Rhodopseudomonas palustris CGA009, complete genome NC_005296 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 39933391 Common hisE phosphoribosyl-ATP pyrophosphatase RPA0314 126 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 39936417 Nonpathogen - hypothetical protein RPA3354 2 None None None 39934381 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase RPA1306 217 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 39936748 Common - NLP/P60 RPA3686 88 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 39935098 Common serB putative phosphoserine phosphatase RPA2029 148 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 39936754 Common - putative peptide ABC transporter, periplasmic peptide-binding protein RPA3692 181 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 39937482 Common - transcriptional regulator, Crp/Fnr family RPA4422 131 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39933397 Common - autoinducer (acylhomoserine lactone) synthase RPA0320 20 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 39936777 Common pimA pimeloyl-CoA ligase RPA3716 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934208 Nonpathogen - hypothetical protein RPA1133 1 COG5373 COG5373, Predicted membrane protein Function unknown 39936912 Common recA recombinase A RPA3851 243 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 39935214 Common - enoyl-CoA hydratase RPA2145 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39935568 Nonpathogen - hypothetical protein RPA2502 3 None None None 39934482 Common - putative ABC transporter protein RPA1408 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39935510 Nonpathogen - hypothetical protein RPA2444 1 None None None 39935360 Common - putative Adenylate/Guanylate cyclase RPA2291 88 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 39937529 Common - hypothetical protein RPA4469 13 None None None 39937709 Common - possible glutaconate CoA-transferase, subunit A RPA4651 40 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 39936541 Common - putative hydroxylase RPA3479 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 39935083 Common - ABC transporter, polyamine transport protein RPA2014 128 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 39934621 Nonpathogen - hypothetical protein RPA1551 7 None None None 39936105 Common mao malic enzyme RPA3042 214 COG0281 SfcA, Malic enzyme Energy production and conversion 39933687 Common - putative glyoxalase II RPA0610 197 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39937787 Common rocF putative arginase RPA4729 99 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 39934442 Common - hypothetical protein RPA1368 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936849 Common - putative ABC transporter, ATP-binding protein RPA3788 151 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 39936091 Common - hypothetical protein RPA3028 83 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 39937702 Common cbbP phosphoribulokinase (phosphopentokinase) (PRK) RPA4644 52 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 39936783 Common ilvM putative branched-chain amino acid transport system permease protein RPA3722 157 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39933784 Common cutA putative periplasmic divalent cation resistance protein CutA RPA0707 121 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 39935482 Common - Acetamidase/Formamidase RPA2415 64 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 39935506 Common - Cation efflux protein RPA2440 26 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 39934054 Common hoxA two component sigma-54-dependent hydrogenase transcriptional regulator hoxA, Fis family RPA0979 187 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39935297 Common trbK probable trbK RPA2228 10 None None None 39935900 Common - possible ATPase family protein RPA2833 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 39937408 Nonpathogen - hypothetical protein RPA4348 2 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 39934905 Common - DUF636 RPA1836 66 COG3791 COG3791, Uncharacterized conserved protein Function unknown 39933983 Common - putative N-formylglutamate amidohydrolase RPA0906 58 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 39933489 Common CPS1 hypothetical protein RPA0412 147 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 39934950 Common - hypothetical protein RPA1881 35 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 39936351 Common - Tyrosine protein kinase:Aminoglycoside phosphotransferase RPA3288 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 39933996 Common - ABC transporter, ATP-binding protein RPA0919 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 39936814 Common - DUF404 RPA3753 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 39937780 Common - putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase RPA4722 214 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 39934332 Common cobS possible cobalamin (5`-phosphate) synthase RPA1257 102 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 39933356 Common - possible FtsK/SpoIIIE family RPA0279 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 39937715 Common kduD putative 2-keto-3-deoxygluconate dehydrogenase RPA4657 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936136 Common acpP acyl carrier protein RPA3073 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934652 Common cyaA Ferredoxin:Adenylate/Guanylate cyclase RPA1582 82 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 39934711 Common - possible transcriptional regulator, AraC family RPA1641 46 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39934067 Common - probable transcriptional regulator, Crp/Fnr family RPA0992 40 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39934505 Nonpathogen draT1 putative NAD+ ADP-ribosyltransferase RPA1431 11 None None None 39936593 Common ftsW putative cell division protein ftsW RPA3531 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 39935756 Common - possible uracil-DNA glycosylase RPA2690 90 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 39933882 Common - possible outer membrane protein RPA0805 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39937234 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit RPA4174 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 39933440 Nonpathogen - Endonuclease/Exonuclease/phosphatase family RPA0363 10 COG1754 COG1754, Uncharacterized C-terminal domain of topoisomerase IA General function prediction only 39937178 Common - conjugal transfer protein trbL RPA4118 24 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 39936302 Common rplX 50S ribosomal protein L24 RPA3239 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 39937093 Common hemD Uroporphyrinogen III synthase HEM4 RPA4033 49 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 39936129 Common ksgA dimethyladenosine transferase RPA3066 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 39933247 Common - hypothetical protein RPA0170 59 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 39937039 Common wpbE putative aminotransferase (aminosugar biosynthesis) RPA3978 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 39936823 Common - putative 2-oxo-3-ene-1,7-dioic acid hydratase RPA3762 174 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 39936765 Nonpathogen - hypothetical protein RPA3703 1 None None None 39934896 Nonpathogen - hypothetical protein RPA1827 2 None None None 39935497 Common - hypothetical protein RPA2431 35 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 39937202 Common - PilT protein, N-terminal RPA4142 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 39936141 Common rpsR 30S ribosomal protein S18 RPA3078 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 39934417 Common - hypothetical protein RPA1343 38 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39935282 Common - hypothetical protein RPA2213 9 None None None 39933192 Common betB putative betaine aldehyde dehydrogenase RPA0112 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39933438 Nonpathogen - hypothetical protein RPA0361 3 None None None 39937560 Common - putative outer membrane protein RPA4502 72 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 39935649 Common valS valyl-tRNA synthetase RPA2583 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39937474 Common - putative RND efflux transporter RPA4414 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39933680 Common ubiG 3-demethylubiquinone-9 3-methyltransferase RPA0603 143 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 39936466 Common - possible transcriptional regulator, TetR family RPA3403 59 COG1309 AcrR, Transcriptional regulator Transcription 39933520 Common - possible transcriptional regulator, XRE family RPA0443 40 COG1396 HipB, Predicted transcriptional regulators Transcription 39934489 Common - possible branched-chain amino acid transport system substrate-binding protein RPA1415 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39937249 Common - hypothetical protein RPA4189 61 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 39936842 Common yihV possible sugar kinase RPA3781 95 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 39936667 Common - trans-aconitate methyltransferase RPA3605 62 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 39933282 Common cycZ heme exporter protein C (ABC transporter permease component) RPA0205 125 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 39933492 Common - Family of unknown function YGGT RPA0415 13 COG0762 COG0762, Predicted integral membrane protein Function unknown 39934464 Common - hypothetical protein RPA1390 34 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 39935597 Nonpathogen - hypothetical protein RPA2531 1 None None None 39936284 Common - heat shock protein HtrA like RPA3221 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39935454 Common - putative ABC transporter, periplasmic Fe+3 siderophore binding protein RPA2385 53 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 39935823 Nonpathogen - hypothetical protein RPA2756 6 None None None 39934640 Common - putative aminopeptidase RPA1570 106 COG1770 PtrB, Protease II Amino acid transport and metabolism 39933423 Common - CysZ-like protein RPA0346 26 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 39937469 Common - ATP-binding protein of sugar ABC transporter RPA4409 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 39937155 Common - putative multidrug-efflux transport protein mexF RPA4095 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39934823 Common ragC putative cation efflux system protein RPA1754 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39936446 Common - possible taurine transport system permease protein RPA3383 94 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39935289 Common - hypothetical protein RPA2220 41 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 39937517 Common - putative sulfide dehydrogenase RPA4457 86 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 39935642 Common - hypothetical protein RPA2576 34 COG3148 COG3148, Uncharacterized conserved protein Function unknown 39935140 Nonpathogen - hypothetical protein RPA2071 4 COG2155 COG2155, Uncharacterized conserved protein Function unknown 39937497 Common metX homoserine O-acetyltransferase RPA4437 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 39935834 Common rplM 50S ribosomal protein L13 RPA2767 223 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 39933360 Common - two-component transcriptional regulator, winged helix family RPA0283 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39934855 Common - enoyl-CoA hydratase RPA1786 156 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39937503 Common - acyl-CoA synthetase RPA4443 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39933287 Common - Pseudouridine synthase:Pseudouridine synthase, Rlu RPA0210 213 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 39936650 Common - hypothetical protein RPA3588 76 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 39933484 Common - possible TonB-dependent receptor (outer membrane siderophore receptor) RPA0407 117 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 39933371 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA RPA0294 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 39934189 Common - hypothetical protein RPA1114 19 None None None 39933555 Common - hypothetical protein RPA0478 45 COG2261 COG2261, Predicted membrane protein Function unknown 39933862 Common - possible cytochrome P450 family proteins RPA0785 79 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 39935950 Nonpathogen - hypothetical protein RPA2885 1 None None None 39937777 Common - molybdo-pterin binding protein RPA4719 70 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 39934813 Common serA possible phosphoglycerate dehydrogenase (serA), Nter fragment RPA1744 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 39934010 Common - putative protease, putative RPA0933 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 39934141 Nonpathogen - hypothetical protein RPA1066 1 None None None 39934937 Common - hypothetical protein RPA1868 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 39933291 Nonpathogen - hypothetical protein RPA0214 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 39937750 Nonpathogen - hypothetical protein RPA4692 2 None None None 39934987 Nonpathogen - hypothetical protein RPA1918 5 None None None 39933265 Common sucB dihydrolipoamide acetyltransferase RPA0188 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 39936704 Common - putative alpha-amylase RPA3642 88 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 39937509 Common - pmethyl-accepting chemotaxis receptor/sensory transducer RPA4449 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39935996 Common - DUF461 RPA2931 81 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 39937336 Nonpathogen - hypothetical protein RPA4276 1 None None None 39935131 Common nosD putative periplasmic ABC transport copper binding protein RPA2062 50 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 39934513 Common anfA Sigma-54 dependent, Iron nitrogenase transcriptional regulator, AnfA RPA1439 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 39935490 Common - hypothetical protein RPA2424 11 None None None 39937106 Common - putative branched-chain amino acid ABC transport system ATP-binding protein RPA4046 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936023 Common - putative DNA-binding protein RPA2958 61 COG3943 COG3943, Virulence protein General function prediction only 39936119 Common - nucleoside-diphosphate-kinase RPA3056 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 39934688 Common ilvX hypothetical protein RPA1618 49 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39934948 Common - Choloylglycine hydrolase RPA1879 52 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 161610777 Common thrC threonine synthase RPA0839 153 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 39936803 Common - putative poly-isoprenyl transferase RPA3742 107 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 39935802 Common mexC2 putative RND multidrug efflux membrane fusion protein MexC precursor RPA2735 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39936057 Common - hypothetical protein RPA2992 27 COG3652 COG3652, Predicted outer membrane protein Function unknown 39933570 Common rpmB 50S ribosomal protein L28 RPA0493 146 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 39933211 Common hydC hydrogenase gamma-fused hydrogenase large and small subunit RPA0134 182 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 39936491 Common - hypothetical protein RPA3428 19 None None None 39937813 Common - possible DNA-3-methyladenine glycosidase II RPA4755 43 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 39934889 Nonpathogen - hypothetical protein RPA1820 3 None None None 39933833 Common - putative amidase RPA0756 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39935302 Common trbB1 conjugal transfer protein trbB RPA2233 222 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 39935899 Common yajC putative membrane protein, possible preprotein translocase RPA2832 168 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 39936879 Common purL phosphoribosylformylglycinamidine synthase I RPA3818 226 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 39933917 Common mpp putative protease RPA0840 202 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 39936326 Common phnB hypothetical protein RPA3263 60 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 39935928 Common - dihydrolipoamide dehydrogenase RPA2863 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 39936328 Common - putative ABC transporter RPA3265 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 39936297 Common rplR 50S ribosomal protein L18 RPA3234 217 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 39937088 Common - possible ABC transport system permease protein RPA4028 145 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39935488 Common - Family of unknown function ThiJ/PfpI RPA2422 80 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39935313 Common - hypothetical protein RPA2244 27 COG5489 COG5489, Uncharacterized conserved protein Function unknown 39933514 Common - hypothetical protein RPA0437 40 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 39933461 Common - hypothetical protein RPA0384 8 None None None 39935626 Common aapJ-1 ABC transporter, periplasmic amino acid binding protein aapJ-1 RPA2560 125 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 39934884 Nonpathogen - hypothetical protein RPA1815 1 None None None 39935058 Nonpathogen - hypothetical protein RPA1989 1 None None None 39935447 Common - putative tonB-dependent receptor protein RPA2378 85 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39934199 Common - hypothetical protein RPA1124 64 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 39936154 Common purF amidophosphoribosyltransferase RPA3091 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 39937343 Common - transcriptional regulator, LysR family RPA4283 114 COG0583 LysR, Transcriptional regulator Transcription 39937384 Nonpathogen - hypothetical protein RPA4324 1 None None None 39934618 Nonpathogen puhA H subunit of photosynthetic reaction center complex RPA1548 9 None None None 39935801 Common - possible epoxide hydrolase-related protein RPA2734 147 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39936001 Common birA biotin--protein ligase RPA2936 207 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 39937646 Common - hypothetical protein RPA4588 10 None None None 39934203 Common - hypothetical protein RPA1128 8 COG4541 COG4541, Predicted membrane protein Function unknown 39934457 Common - putative transcriptional regulator, ModE family RPA1383 91 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 39935309 Common - possible replication protein A RPA2240 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 39933205 Common - possible permease protein of sugar ABC transporter RPA0128 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 39935007 Common - sensor histidine kinase, possible pleC RPA1938 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39934345 Nonpathogen - hypothetical protein RPA1270 2 None None None 39934455 Nonpathogen - hypothetical protein RPA1381 1 None None None 39936197 Common - hypothetical protein RPA3134 22 None None None 39936728 Common - possible ATP-binding component of ABC transporter RPA3666 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 39933306 Nonpathogen - hypothetical protein RPA0229 2 None None None 39934570 Common mexD2 RND multidrug efflux transporter MexD RPA1498 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39937285 Common - RNA polymerase sigma factor RPA4225 168 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39934702 Common ctrA two-component cell cycle transcriptional regulator ctrA, winged helix family RPA1632 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39934865 Common - putative Adenylate/Guanylate cyclase RPA1796 86 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 39936683 Common vanB putative vanillate O-demethylase oxidoreductase RPA3621 104 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 39937887 Common caiC putative crotonobetaine/carnitine-CoA ligase RPA4829 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936037 Common bioF 8-amino-7-oxononanoate synthase RPA2972 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 39933083 Common recF recombination protein F RPA0003 114 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 39936882 Common purC2 phosphoribosylaminoimidazole-succinocarboxamide synthase RPA3821 161 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 39935608 Common - possible TrapT family, dctQ subunit, C4-dicarboxylate transport RPA2542 29 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 39933938 Common - possible CobW protein involved in cobalamin synthesis RPA0861 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 39936890 Common - transcription elongation factor regulatory protein RPA3829 108 COG0782 GreA, Transcription elongation factor Transcription 39935684 Common - putative sulfonate transport system substrate-binding protein RPA2618 79 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39933750 Common hbaR Hydroxybenzoate anaerobic degradation regulatory protein HbaR, Crp/Fnr family RPA0673 118 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39935890 Common - hypothetical protein RPA2823 38 COG2388 COG2388, Predicted acetyltransferase General function prediction only 39936455 Common - possible nifU homolog RPA3392 82 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 39935674 Common - possible sulfonate binding protein RPA2608 97 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39933699 Common fmt methionyl-tRNA formyltransferase RPA0622 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 39937542 Common - putative sensor (PAS) domain for methyl-accepting chemotaxis sensory transducer RPA4482 91 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 39933095 Common fixG 4Fe-4S ferredoxin, iron-sulfur binding domain RPA0015 82 COG0348 NapH, Polyferredoxin Energy production and conversion 39937612 Common dctM2 TrapT family, dctM subunit, C4-dicarboxylate transport RPA4554 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 39934135 Common - hypothetical protein RPA1060 5 None None None 39935808 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III RPA2741 227 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 39935152 Common cobB cobyrinic acid a,c-diamide synthase RPA2083 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 39937185 Common - hypothetical protein RPA4125 10 None None None 39937803 Nonpathogen - hypothetical protein RPA4745 2 None None None 39934190 Common - hypothetical protein RPA1115 80 COG2128 COG2128, Uncharacterized conserved protein Function unknown 39935770 Common - possible Na+/? antiporter RPA2704 28 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 39935369 Common - Bacterial regulatory protein, LuxR family RPA2300 9 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 39934673 Common - putative fatty acid desaturase RPA1603 38 COG3239 DesA, Fatty acid desaturase Lipid metabolism 39937721 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4663 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39937101 Common - putative branched-chain amino acid ABC transport system ATP-binding protein RPA4041 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935267 Common - possible multidrug efflux protein RPA2198 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39935657 Common nifR3 putative nitrogen regulation protein nifR3 RPA2591 205 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 39933692 Common dnaX DNA polymerase III subunits gamma and tau RPA0615 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 39936653 Common - Endoribonuclease L-PSP RPA3591 139 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 39933883 Common - possible high-affinity branched-chain amino acid transport system substrate-binding protein RPA0806 104 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935206 Common - probable acyl-CoA dehydrogenase RPA2137 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934089 Nonpathogen - hypothetical protein RPA1014 3 None None None 39937277 Common - hypothetical protein RPA4217 56 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 39935636 Common - hypothetical protein RPA2570 62 COG3496 COG3496, Uncharacterized conserved protein Function unknown 39933183 Common - Cobalamin synthesis protein/P47K RPA0103 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 39937269 Common glnA glutamine synthetase II RPA4209 75 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 39933968 Common gltB glutamate synthase, large subunit RPA0891 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 39937579 Common - Thioesterase superfamily RPA4521 23 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39937609 Common - hypothetical protein RPA4551 12 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 39935105 Common - possible transcriptional regulator, GntR family RPA2036 125 COG2186 FadR, Transcriptional regulators Transcription 39936022 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) RPA2957 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39937132 Common greA transcription elongation factor GreA RPA4072 204 COG0782 GreA, Transcription elongation factor Transcription 39936423 Common pssN putative capsule polysaccharide export outer membrane protein RPA3360 97 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 39937676 Common nifK nitrogenase molybdenum-iron protein beta chain, nifK RPA4618 51 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39936730 Common - putative ABC transporter system permease component, possible fused protein RPA3668 164 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39935244 Common - Transglutaminase-like domain RPA2175 109 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 39935877 Common - possible exsB protein RPA2810 154 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 39935223 Common - putative acyltransferase RPA2154 19 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 39937230 Common - possible branched-chain amino acid ABC transport system substrate-binding protein RPA4170 98 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39937463 Common - morphinone reductase RPA4403 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 39936826 Common paaD putative phenylacetic acid degradation protein PaaD RPA3765 43 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 39934259 Common - DUF58 RPA1184 56 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 39933850 Nonpathogen - hypothetical protein RPA0773 1 None None None 39937350 Common - hypothetical protein RPA4290 14 COG3223 COG3223, Predicted membrane protein Function unknown 39936336 Common rplK 50S ribosomal protein L11 RPA3273 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 39934564 Nonpathogen pucAe light harvesting protein B-800-850, alpha chain E (antenna pigment protein, alpha chain E) (LH II-E alpha) RPA1492 7 None None None 39934124 Common - hypothetical protein RPA1049 54 COG3174 COG3174, Predicted membrane protein Function unknown 39935113 Common - hypothetical protein RPA2044 11 None None None 39936621 Common arsR3 transcriptional regulator, ArsR family, ArsR3 RPA3559 136 COG0640 ArsR, Predicted transcriptional regulators Transcription 39935730 Nonpathogen - hypothetical protein RPA2664 4 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39933102 Common - DSBA oxidoreductase RPA0022 36 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 39933169 Nonpathogen - hypothetical protein RPA0089 4 COG5490 COG5490, Uncharacterized conserved protein Function unknown 39936212 Common - hypothetical protein RPA3149 24 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39936414 Common - possible glycosyl transferase RPA3351 14 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 39935815 Common - possible short-chain dehydrogenase RPA2748 229 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 39934044 Common hupH hydrogenase expression/formation protein hupH RPA0969 20 None None None 39937654 Common fabG5 putative 3-oxoacyl-acyl carrier protein reductase RPA4596 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 39936759 Common emrA putative multidrug resistance protein RPA3697 115 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39934317 Common fadD1 putative long-chain-fatty-acid CoA ligase RPA1242 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39935388 Common - hypothetical protein RPA2319 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 39935397 Common - putative ABC transporter permease protein RPA2328 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39933926 Common - hypothetical protein RPA0849 10 None None None 39935402 Common ctpC putative cation transport ATPase, possible copper transporter RPA2333 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 39936424 Nonpathogen - hypothetical protein RPA3361 1 None None None 39936219 Common - hypothetical protein RPA3156 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 39933501 Common - transcriptional regulator, FUR family; probable iron response regulator IRR RPA0424 112 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 39934487 Common - transcriptional regulator, IclR family RPA1413 92 COG1414 IclR, Transcriptional regulator Transcription 39934163 Nonpathogen - hypothetical protein RPA1088 1 None None None 39934668 Common - Peptidylprolyl isomerase, FKBP-type:Acyltransferase 3 family RPA1598 15 None None None 39937502 Common - ErfK/YbiS/YcfS/YnhG RPA4442 80 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39933385 Common hslV ATP-dependent protease peptidase subunit RPA0308 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 39936992 Common flgK2 possible flagellar hook-associated protein 1 FlgK RPA3931 128 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 39936636 Common thiS putative thiamin biosynthesis ThiS RPA3574 21 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 39934981 Common - homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg15 RPA1912 26 None None None 39933458 Common glgC glucose-1-phosphate adenylyltransferase RPA0381 172 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 39935129 Common nosR regulatory protein NosR RPA2060 84 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 39933633 Common - HNH endonuclease:HNH nuclease RPA0556 102 COG1403 McrA, Restriction endonuclease Defense mechanisms 39935270 Common - quinone oxidoreductase RPA2201 85 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 39935481 Common - putative urea/short-chain amide transport system ATP-binding protein RPA2414 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936697 Common gnd 6-phosphogluconate dehydrogenase-like protein RPA3635 183 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 39937258 Common - Amidohydrolase 2 RPA4198 57 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 39934850 Common phbH 4-hydroxybenzoate 3-monooxygenase RPA1781 72 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 39934153 Common - probable transcriptional regulator, AraC family RPA1078 145 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39936628 Nonpathogen - hypothetical protein RPA3566 1 None None None 39936610 Common - possible serine protease/outer membrane autotransporter RPA3548 71 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 39934646 Common - putative glutathione S-transferase RPA1576 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39935346 Common - possible ABC transporter, permease protein RPA2277 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39933319 Common trmD putative tRNA (guanine-N1)-methyltransferase RPA0242 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 39934793 Common paaK phenylacetyl-CoA ligase RPA1723 117 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 39933529 Common - Glycoprotease (M22) metalloprotease RPA0452 156 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 39937566 Common - hypothetical protein RPA4508 11 COG4729 COG4729, Uncharacterized conserved protein Function unknown 39936603 Nonpathogen - hypothetical protein RPA3541 1 None None None 39935337 Common - Flavin reductase-like RPA2268 70 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 39933148 Common trpF N-(5'-phosphoribosyl)anthranilate isomerase RPA0068 194 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 39935723 Common - putative beta (1-6) glucans synthase RPA2657 16 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 39933742 Common hbaH putative ABC transporter subunit, ATP-binding component RPA0665 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936583 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase RPA3521 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 39936015 Common nuoC NADH dehydrogenase subunit C RPA2950 177 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 39933876 Common - putative carbonic anhydrase RPA0799 149 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 39935041 Common - sensor histidine kinase RPA1972 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39933950 Common - hypothetical protein RPA0873 34 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 39935813 Nonpathogen - hypothetical protein RPA2746 2 None None None 39935079 Common motB1 putative chemotaxis protein motB1 RPA2010 107 COG1360 MotB, Flagellar motor protein Cell motility and secretion 39936543 Nonpathogen - hypothetical protein RPA3481 3 None None None 39936085 Common - putative diguanylate cyclase (GGDEF) RPA3022 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39936458 Common - hypothetical protein RPA3395 16 None None None 39934327 Common - putative high-affinity branched-chain amino acid transport system permease protein RPA1252 119 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934270 Common fixR1 short-chain dehydrogenase RPA1195 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934186 Nonpathogen - hypothetical protein RPA1111 1 None None None 39937310 Common fixK transcriptional regulator FixK RPA4250 142 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39937549 Common - putative chromosome segregation SMC protein RPA4489 177 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 39937841 Nonpathogen - hypothetical protein RPA4783 3 None None None 39937332 Common - hypothetical protein RPA4272 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 39934126 Common - pyruvate phosphate dikinase RPA1051 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 39937190 Common - hypothetical protein RPA4130 22 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 39935060 Common - hypothetical protein RPA1991 23 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 39935315 Nonpathogen - hypothetical protein RPA2246 1 None None None 39935010 Common - possible 2-nitropropane dioxygenase RPA1941 110 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 39936248 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA3185 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39935226 Common - hypothetical protein RPA2157 11 None None None 39934744 Common cheY3 response regulator receiver, CheY3 RPA1674 14 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39933406 Common rph ribonuclease PH RPA0329 182 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 39933540 Common - transcriptional regulator, TetR family RPA0463 44 COG1309 AcrR, Transcriptional regulator Transcription 39936237 Common - hypothetical protein RPA3174 102 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 39936619 Common - Thiol-disulfide isomerase and thioredoxins RPA3557 62 None None None 39934028 Common - Nucleoside 2-deoxyribosyltransferase RPA0951 19 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 39935019 Common pqqE pyrroloquinoline quinone biosynthesis protein PqqE RPA1950 155 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 39933300 Common - hypothetical protein RPA0223 27 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 39935265 Common - hypothetical protein RPA2196 9 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 39934544 Common - putative dipeptide transport permease protein RPA1472 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39933954 Common - hypothetical protein RPA0877 34 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 39935581 Common kamA putative L-lysine 2,3-aminomutase RPA2515 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 39934020 Common pgk phosphoglycerate kinase RPA0943 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 39933108 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase RPA0028 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 39934240 Common - Pseudouridine synthase, Rsu:RNA-binding S4:Pseudouridine synthase RPA1165 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 39936601 Common - Putative peptidoglycan binding domain 1:N-acetylmuramoyl-L-alanine amidase, family 2 RPA3539 109 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 39937153 Nonpathogen - hypothetical protein RPA4093 1 None None None 39937010 Common wbpX possible glycosyltransferase WbpX RPA3949 96 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39937013 Common - possible oxidoreductase Rmd RPA3952 138 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39934069 Common - hypothetical protein RPA0994 5 COG2158 COG2158, Uncharacterized protein containing a Zn-finger-like domain General function prediction only 39936907 Common - GCN5-related N-acetyltransferase RPA3846 34 COG0456 RimI, Acetyltransferases General function prediction only 39935888 Common - possible ion transporter RPA2821 80 None None None 39937060 Common - possible coenzyme PQQ synthesis protein E RPA3999 130 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 39933924 Common atpI FoF1 ATP synthase, subunit I RPA0847 13 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 39934008 Common ubiD Carboxylyase-related protein RPA0931 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 39936743 Common - secretory protein kinase, cpaF RPA3681 165 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 39933781 Common - hypothetical protein RPA0704 70 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 39934361 Nonpathogen - hypothetical protein RPA1286 1 None None None 39935781 Common - acyl-CoA synthetase RPA2714 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936356 Common - putative branched-chain amino acid transport system ATP-binding protein RPA3293 248 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39937587 Common arsC4 putative arsenate reductase RPA4529 96 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 39935798 Common hppA membrane-bound proton-translocating pyrophosphatase RPA2731 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 39934639 Common - O-acetylhomoserine aminocarboxypropyltransferase RPA1569 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 39935307 Common - hypothetical protein RPA2238 23 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 39937424 Common - hypothetical protein RPA4364 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 39936334 Common - putative D-isomer specific 2-hydroxyacid dehydrogenase RPA3271 222 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 39935934 Common - possible flavin-dependent oxidoreductase RPA2869 104 COG0431 COG0431, Predicted flavoprotein General function prediction only 39934777 Common fcs1 acyl-CoA synthetase RPA1707 181 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 39935000 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA1931 163 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39936908 Common alaS alanyl-tRNA synthetase RPA3847 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39933468 Common - possible alkaline phosphatase RPA0391 84 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 39934098 Nonpathogen - hypothetical protein RPA1023 2 None None None 39934910 Common - hypothetical protein RPA1841 12 None None None 39935912 Common tatC putative sec-independent protein translocase component TatC RPA2847 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 39937364 Common - hypothetical protein RPA4304 29 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 39934917 Common - Uncharacterized iron-regulated membrane protein DUF337 RPA1848 46 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 39933278 Common - hypothetical protein RPA0201 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 39934384 Common - possible transposase RPA1309 5 None None None 39933583 Common - site-specific integrase/recombinase XerD RPA0506 221 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 39936346 Common tuf elongation factor Tu RPA3283 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 39936726 Common ureD possible urease accessory protein D RPA3664 74 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 39933897 Common gst2 putative glutathionine S-transferase RPA0820 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39934326 Common - putative branched-chain amino acid transport system permease protein RPA1251 161 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39936954 Common - putative carboxylesterase RPA3893 58 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 39933678 Common - probable DMT superfamily transporter RPA0601 44 COG2510 COG2510, Predicted membrane protein Function unknown 39936362 Common - putative long-chain-fatty-acid CoA ligase RPA3299 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936068 Common kdpB potassium-transporting ATPase subunit B RPA3003 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 39935777 Common - arginyl-tRNA-protein transferase RPA2710 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 39933442 Common - Beta-lactamase-like RPA0365 212 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39934993 Common - Cobalamin synthesis protein/P47K RPA1924 59 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 39937368 Common serA2 putative phosphoglycerate dehydrogenase RPA4308 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 39934355 Common - hypothetical protein RPA1280 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 39937199 Nonpathogen - hypothetical protein RPA4139 1 None None None 39936230 Common - hypothetical protein RPA3167 31 COG5654 COG5654, Uncharacterized conserved protein Function unknown 39934415 Common - hypothetical protein RPA1341 71 None None None 39935739 Common - possibly involved in transport RPA2673 94 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 39936577 Common - aminopeptidase P RPA3515 227 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 39937684 Common - Protein of unknown function from Deinococcus and Synechococcus RPA4626 13 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 39936049 Common - putative diguanylate cyclase (GGDEF) RPA2984 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39937556 Common trpG anthranilate synthase RPA4498 233 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 39933894 Common - acetyl-CoA acetyltransferase RPA0817 178 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39934924 Common - hypothetical protein RPA1855 21 None None None 39937583 Nonpathogen - hypothetical protein RPA4525 2 None None None 39936279 Common - sensor histidine kinase with multiple PAS and a response regulator receiver domain RPA3216 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39935026 Common - alkanal monooxygenase (LuxA-like protein) RPA1957 85 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 39934877 Common czcA1 putative RND divalent metal cation efflux transporter CzcA RPA1808 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 39934517 Common - transcriptional regulator, GntR family RPA1443 58 COG1802 GntR, Transcriptional regulators Transcription 39934536 Common - possible glutamine amidotransferase RPA1464 116 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 39934052 Common hypD hydrogenase expression/formation protein hypD RPA0977 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 39933150 Common trpA tryptophan synthase subunit alpha RPA0070 213 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 39936515 Common - Phenylacetic acid degradation-related protein RPA3452 36 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39936121 Nonpathogen - hypothetical protein RPA3058 3 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 39937386 Common sulP sulfate transporter family protein RPA4326 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 39937222 Common - putative taurine ABC transport system permease protein RPA4162 201 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39933326 Common - hypothetical protein RPA0249 9 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 39933621 Nonpathogen - LrgA family holin protein RPA0544 4 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 39936694 Common - DUF24, predicted transcriptional regulator, related to MarR family RPA3632 102 COG1733 COG1733, Predicted transcriptional regulators Transcription 39933844 Common - putative diguanylate cyclase (GGDEF) with PAS/PAC domain RPA0767 181 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39937512 Common - putative aromatic-L-amino-acid decarboxylase RPA4452 110 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 39934749 Nonpathogen - hypothetical protein RPA1679 3 None None None 39937785 Common glgA2 glycogen phosphorylase RPA4727 142 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 39935411 Common - putative transmembrane transport protein RPA2342 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936990 Common - flagellin RPA3929 104 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 39934063 Common - putative branched-chain amino acid ABC transporter, ATP-binding protein RPA0988 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936520 Common - possible TrapT family, dctP subunit, C4-dicarboxylate periplasmic binding protein RPA3458 35 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 39937734 Common - probable transcriptional regulator, MarR family RPA4676 60 COG1846 MarR, Transcriptional regulators Transcription 39936533 Common - ABC transporter, ATP-binding protein RPA3471 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 39933811 Common fdsA NAD-dependent formate dehydrogenase alpha subunit RPA0734 215 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 39936937 Common fumA fumarate hydratase, class I RPA3876 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 39937353 Nonpathogen - hypothetical protein RPA4293 2 None None None 39937704 Common - putative carboxylesterase RPA4646 94 COG1647 COG1647, Esterase/lipase General function prediction only 39933249 Nonpathogen - hypothetical protein RPA0172 3 None None None 39937018 Nonpathogen - Hpt domain RPA3957 3 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 39934250 Common - response regulator receiver (CheY-like protein) RPA1175 218 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39936631 Nonpathogen - hypothetical protein RPA3569 2 None None None 39937123 Nonpathogen - hypothetical protein RPA4063 1 None None None 39933512 Common rbfA ribosome-binding factor A RPA0435 135 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 39937868 Common - predicted permease RPA4810 43 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 39937356 Nonpathogen - hypothetical protein RPA4296 3 None None None 39933721 Common flgD possible basal-body rod modification protein flgD RPA0644 88 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 39936014 Common nuoD NADH dehydrogenase subunit D RPA2949 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 39936983 Common - putative acetoin dehydrogenase (TPP-dependent) beta chain RPA3922 208 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 39933101 Common - possible short chain dehydrogenase RPA0021 125 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 39937046 Common - ADP-L-glycero-D-mannoheptose-6-epimerase RPA3985 223 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39935867 Common - hypothetical protein RPA2800 9 None None None 39937642 Common - possible endoglucanase RPA4584 13 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 39937744 Common - possible ABC transporter, periplasmic amino acid-binding protein RPA4686 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 39933085 Common hpd 4-hydroxyphenylpyruvate dioxygenase RPA0005 77 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 39937732 Common - hypothetical protein RPA4674 8 None None None 39936866 Nonpathogen - hypothetical protein RPA3805 3 None None None 39933749 Common hbaD 4-hydroxybenzoyl-CoA reductase, third of three subunits RPA0672 94 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 39937164 Nonpathogen - hypothetical protein RPA4104 2 None None None 39937728 Common fahA fumarylacetoacetate hydrolase RPA4670 60 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 39934767 Common - Competence-damaged protein RPA1697 67 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 39934627 Common - response regulator receiver with duplicated domains RPA1557 173 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39933594 Common - transcriptional regulator, Fur family; probable zinc uptake regulator ZUR RPA0517 117 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 39936178 Common - probable acyl-CoA dehydrogenase RPA3115 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39936523 Common - hypothetical protein RPA3461 23 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 39933222 Common - Metal dependent phosphohydrolase with a response regulator receiver domain RPA0145 218 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 39935579 Common efp elongation factor P RPA2513 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 39935572 Common - possible acetyltransferase RPA2506 51 COG0456 RimI, Acetyltransferases General function prediction only 39933711 Common rpmH 50S ribosomal protein L34 RPA0634 25 None None None 39933685 Common - hypothetical protein RPA0608 31 None None None 39937218 Common potI ABC transporter, polyamine transport protein, permease protein RPA4158 179 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 39934221 Common - hypothetical protein RPA1146 24 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 39933656 Nonpathogen - hypothetical protein RPA0579 1 None None None 39934104 Common - possible CoA transferase, subunit A RPA1029 40 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 39937300 Common - GCN5-related N-acetyltransferase:CoA Binding Domain RPA4240 157 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 39937211 Common - transcriptional regulator, LysR family RPA4151 172 COG0583 LysR, Transcriptional regulator Transcription 39934111 Common polN possible phage DNA polymerase RPA1036 155 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 39933642 Common - putative polyhydroxybutyrate depolymerase RPA0565 32 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 39934598 Nonpathogen pufA light-harvesting complex 1 alpha chain RPA1526 5 None None None 39937456 Common - possible transglycolase RPA4396 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 39936848 Nonpathogen - hypothetical protein RPA3787 3 None None None 39934249 Common - hypothetical protein RPA1174 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 39934674 Common - hypothetical protein RPA1604 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 39933708 Common - GTPase EngB RPA0631 185 COG0218 COG0218, Predicted GTPase General function prediction only 39935691 Common - putative cystathionine or methionine gamma-lyase RPA2625 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 39935326 Common arsC1 arsenate reductase pump modifier RPA2257 111 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 39937439 Common ribF putative riboflavin kinase ribF RPA4379 211 COG0196 RibF, FAD synthase Coenzyme metabolism 39936942 Common - hypothetical protein RPA3881 22 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 39933253 Common atpD F0F1 ATP synthase subunit beta RPA0176 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 39935476 Nonpathogen - possible AmiR antitermination protein RPA2409 3 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 39937141 Common - possible pilus assembly protein cpaB RPA4081 57 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 39933534 Common - possible cabohydrate kinase RPA0457 191 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 39934559 Common - hypothetical protein RPA1487 24 COG4309 COG4309, Uncharacterized conserved protein Function unknown 39936055 Common - hypothetical protein RPA2990 33 None None None 39934402 Common - sensor histidine kinase with a GAF and an unknown domain RPA1328 224 COG3899 COG3899, Predicted ATPase General function prediction only 39933828 Common cysH phosphoadenosine phosphosulfate reductase RPA0751 144 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 39936681 Common vanA putative vanillate O-demethylase oxygenase, iron-sulfur subunit RPA3619 74 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 39935024 Common - glutathione dependent formaldehyde dehydrogenase RPA1955 205 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 39934239 Common - possible cytidine and deoxycytidylate deaminase RPA1164 213 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 39937693 Common feoB ferrous iron transport protein B RPA4635 175 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 39936767 Common glpK glycerol kinase RPA3705 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 39934583 Common - Alpha/beta hydrolase fold RPA1511 122 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39933218 Common cheW1-1 chemotaxis signal transduction/oligomerization protein CheW1-1 RPA0141 119 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 39934038 Common hupL hydrogenase large chain RPA0963 103 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 39933973 Common - putative 3-oxoacyl-acyl carrier protein reductase RPA0896 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935072 Common - probable cytochrome c precursor RPA2003 77 COG3258 COG3258, Cytochrome c Energy production and conversion 39935156 Common cobK cobalt-precorrin-6x reductase RPA2087 74 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 39934575 Common - hypothetical protein RPA1503 16 COG2267 PldB, Lysophospholipase Lipid metabolism 39934566 Nonpathogen - hypothetical protein RPA1494 2 None None None 39933889 Common - putative transmembrane protein RPA0812 28 None None None 39933826 Common cysT putative sulfate ABC transporter, permease component RPA0749 222 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 39934750 Common - putative response regulator and cylclic diguanylate phosphodiesterase (EAL) RPA1680 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 39935511 Common - hypothetical protein RPA2445 97 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 39933766 Common phnM1 possible phosphonate utilization (C-P lyase) component RPA0689 54 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 39936927 Common - hypothetical protein RPA3866 21 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 39934440 Nonpathogen soxZ1 putative sulfur oxidation protein RPA1366 22 None None None 39933733 Common badC putative alcohol dehydrogenase RPA0656 205 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39933860 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) RPA0783 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39933561 Common paaG1 enoyl-CoA hydratase RPA0484 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39935173 Common - hypothetical protein RPA2104 23 None None None 39937806 Common hbdA 3-hydroxybutyryl-CoA dehydrogenase RPA4748 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 39934872 Common dnaE2 error-prone DNA polymerase RPA1803 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 39933373 Common rho transcription termination factor Rho RPA0296 205 COG1158 Rho, Transcription termination factor Transcription 39937451 Common - Metallo-phosphoesterase RPA4391 35 COG1409 Icc, Predicted phosphohydrolases General function prediction only 39937623 Common - putative diguanylate cyclase (GGDEF) RPA4565 173 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39935435 Nonpathogen - hypothetical protein RPA2366 1 None None None 39934751 Common - sensor histidine kinase with a response regulator receiver domain RPA1681 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39935425 Common - putative cystathionine beta-synthase RPA2356 218 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 39937206 Common - DUF323 RPA4146 84 COG1262 COG1262, Uncharacterized conserved protein Function unknown 39934946 Common - hypothetical protein RPA1877 15 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 39936381 Common - transcriptional regulator, Crp/Fnr family RPA3318 101 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39936253 Common - possible dihydrodipicoline synthase related protein RPA3190 142 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 39935144 Common - putative signal transduction histidine kinase with GAF and PAS/PAC domains RPA2075 128 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39933777 Common phnC PhnC protein, phosphonate ABC transporter, ATP-binding component RPA0700 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 39933602 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase RPA0525 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 39935416 Common - possible vanadium nitrogenase associated protein N (U51863) RPA2347 64 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39935183 Common nrtC1 putative nitrate transport system ATP-binding protein RPA2114 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39937558 Nonpathogen - hypothetical protein RPA4500 1 None None None 39935920 Common - dGTP triphosphohydrolase RPA2855 165 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 39937651 Common - aminotransferase RPA4593 200 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 39936262 Nonpathogen - hypothetical protein RPA3199 2 None None None 39933317 Common leuC isopropylmalate isomerase large subunit RPA0240 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 39934330 Common fmdA formamide amidohydrolase RPA1255 63 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 39936171 Common - hypothetical protein RPA3108 7 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 39937445 Common PA0781 putative outer membrane hemin/siderophore receptor protein RPA4385 89 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39934603 Common - possible Bch2, light harvesting pigment Major Facilitator Family (MFS) transporter RPA1531 24 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 39934630 Common cbbS ribulose-bisphosphate carboxylase small chain RPA1560 29 COG4451 RbcS, Ribulose bisphosphate carboxylase small subunit Energy production and conversion 39933229 Common - hypothetical protein RPA0152 85 COG1720 COG1720, Uncharacterized conserved protein Function unknown 39936679 Common - hypothetical protein RPA3617 9 COG2261 COG2261, Predicted membrane protein Function unknown 39936079 Common phyB1 Bacteriophytochrome (light-regulated signal transduction histidine kinase), PhyB1 RPA3015 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 39937861 Common - putative outer membrane hemin/siderophore receptor protein RPA4803 119 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 39933270 Common - AFG1-like ATPase RPA0193 100 COG1485 COG1485, Predicted ATPase General function prediction only 39935059 Common - possible sulfatase RPA1990 68 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 39936556 Common - possible TctC subunit of the Tripartite Tricarboxylate Transport(TTT) Family RPA3494 62 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 39937852 Common qxtB putative cytochrome bd-quinol oxidase subunit II RPA4794 146 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 39933472 Common - Metal dependent phosphohydrolase RPA0395 52 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 39933589 Common mutS DNA mismatch repair protein RPA0512 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 39933965 Common - putative lysophospholipase L2 RPA0888 77 COG2267 PldB, Lysophospholipase Lipid metabolism 39933728 Common aliA cyclohexanecarboxylate-CoA ligase RPA0651 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936007 Common nuoI1 NADH dehydrogenase subunit I RPA2942 195 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 39935445 Common - hypothetical protein RPA2375 20 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39937379 Nonpathogen - hypothetical protein RPA4319 1 None None None 39935321 Common - putative ardC antirestriction protein RPA2252 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 39934840 Nonpathogen - hypothetical protein RPA1771 3 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 39936274 Common - TPR repeat RPA3211 24 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 39936986 Common - putative dTDP-glucose 4,6-dehydratase RPA3925 229 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 39936997 Common - hypothetical protein RPA3936 24 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39936595 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase RPA3533 212 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 39935542 Common - putative diguanylate cyclase (GGDEF) RPA2476 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39935353 Common - SugE homolog, probable drug efflux protein RPA2284 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 39935734 Nonpathogen - hypothetical protein RPA2668 1 None None None 39936893 Common - putative diguanylate cyclase (GGDEF) with PAS/PAC domain RPA3832 187 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39934709 Common - possible oxalate/formate Major Facilitator Family (MFS) antiporter RPA1639 96 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 39935956 Common trpC indole-3-glycerol phosphate synthase RPA2891 218 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 39934952 Nonpathogen - hypothetical protein RPA1883 1 None None None 39936419 Nonpathogen - hypothetical protein RPA3356 2 None None None 39934842 Common - putative DMT superfamily multidrug-efflux transporter RPA1773 139 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 39933479 Common - possible transcriptional regulator, TetR family RPA0402 84 COG1309 AcrR, Transcriptional regulator Transcription 39934849 Common - Phenylacetic acid degradation-related protein RPA1780 10 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39934350 Common - hypothetical protein RPA1275 20 COG4297 COG4297, Uncharacterized protein containing double-stranded beta helix domain Function unknown 39933382 Common - possible DNA mismatch repair protein (MutS) RPA0305 80 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 39933139 Common - L-carnitine dehydratase/bile acid-inducible protein F RPA0059 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39936319 Nonpathogen - hypothetical protein RPA3256 2 None None None 39933607 Common - hypothetical protein RPA0530 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 39934279 Common - hypothetical protein RPA1204 17 None None None 39933116 Common - hypothetical protein RPA0036 47 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 39934230 Common - putative pmbA protein, maturation of antibiotic MccB17 RPA1155 160 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 39934263 Common - possible poly(A) polymerase RPA1188 189 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 39936797 Common pstS2 putative phosphate transport system substrate-binding protein RPA3736 104 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 39933160 Common dut putative deoxyuridine 5'triphosphate nucleotidohydrolase RPA0080 183 COG0756 Dut, dUTPase Nucleotide transport and metabolism 39937753 Common ligR transcriptional regulator ligR, LysR family RPA4695 192 COG0583 LysR, Transcriptional regulator Transcription 39934012 Common - hypothetical protein RPA0935 37 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 39936715 Common - hypothetical protein RPA3653 70 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 39934929 Common - hypothetical protein RPA1860 26 COG5447 COG5447, Uncharacterized conserved protein Function unknown 39935036 Common - putative component of multidrug efflux system RPA1967 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39934614 Common bchH magnesium chelatase subunit H RPA1544 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 39937135 Common trxB thioredoxin reductase RPA4075 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 39934070 Common - probable acyl-CoA dehydrogenase RPA0995 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39937533 Nonpathogen - hypothetical protein RPA4473 9 None None None 39937306 Common - CBS domain:Transport-associated domain RPA4246 162 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 39937054 Common - hypothetical protein RPA3993 46 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39936167 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B RPA3104 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 39935538 Common - hypothetical protein RPA2472 8 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 39937009 Common - hypothetical protein RPA3948 3 None None None 39934661 Nonpathogen - hypothetical protein RPA1591 13 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 39936800 Common - hypothetical protein RPA3739 17 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 39933413 Common - NADPH-dependent FMN reductase RPA0336 87 COG0431 COG0431, Predicted flavoprotein General function prediction only 39935229 Common - short chain dehydrogenase RPA2160 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935838 Common - possible transport protein/permease RPA2771 134 COG0628 PerM, Predicted permease General function prediction only 39934109 Common rnh2 possible ribonuclease HII RPA1034 206 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 39937373 Common - putative acetyltransfersase RPA4313 44 COG0456 RimI, Acetyltransferases General function prediction only 39933796 Common cobD putative cobalamin biosynthetic protein cobD RPA0719 146 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 39934019 Common - hypothetical protein RPA0942 12 None None None 39936435 Nonpathogen - hypothetical protein RPA3372 3 None None None 39935125 Common czcA2 RND divalent metal cation efflux transporter CzcA RPA2056 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 39935162 Common - tricarballylate dehydrogenase RPA2093 43 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 39936483 Common - hypothetical protein RPA3420 12 None None None 39936873 Common - putative holocytochrome c synthase RPA3812 99 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 39935252 Common - DSBA oxidoreductase RPA2183 47 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 39937513 Common - Metallo-phosphoesterase:Conserved hypothetical protein 282 RPA4453 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 39935874 Nonpathogen - hypothetical protein RPA2807 9 None None None 39937472 Common - hypothetical protein RPA4412 90 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 39933664 Common - putative cationic amino acid transporter RPA0587 161 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 39933644 Common - probable transcriptional regulator, AraC family RPA0567 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39934906 Common - possible methylmalonyl-CoA small subunit RPA1837 107 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 39937069 Common - putative signal transduction histidine kinase with GAF domain RPA4009 102 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39933556 Common fabG1 possible 3-oxoacyl-acyl carrier protein reductase RPA0479 221 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934310 Common - possible Leucine-Binding Protein (LBP) RPA1235 141 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39936081 Common rphyB response regulator receiver (CheY-like protein) RPA3017 135 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 39937315 Common nuoK2 NADH-ubiquinone dehydrogenase chain K RPA4255 28 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 39933564 Common - hypothetical protein RPA0487 128 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 39934247 Common - possible outer membrane protein RPA1172 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39933362 Common - hypothetical protein RPA0285 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 39933421 Common - hypothetical protein RPA0344 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 39935589 Common - putative lactoylglutathione lyase RPA2523 123 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 39933682 Common ptsP nitrogen regulatory protein PTSI(NTR) RPA0605 232 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 39933194 Nonpathogen - hypothetical protein RPA0114 2 None None None 39934466 Common - nitroreductase family proteins RPA1392 70 COG0778 NfnB, Nitroreductase Energy production and conversion 39933185 Common - transcriptional regulator, GntR family with aminotransferase domain RPA0105 162 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 39935647 Common - putative outer membrane protein RPA2581 142 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39937275 Common cysG putative siroheme synthase RPA4215 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 39935280 Common - DEAD/DEAH box helicase:Helicase, C-terminal RPA2211 10 None None None 39934460 Common ptxA putative ATP-binding component of ABC phosphonate transporter RPA1386 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 39935376 Common - possible tonB-dependent receptor precursor RPA2307 127 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 39937479 Common ggt3 putative gamma-glutamyltranspeptidase RPA4419 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 39933390 Common hisF imidazole glycerol phosphate synthase subunit HisF RPA0313 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 39934100 Nonpathogen - possible Ectothiorhodospira Vacuolata Cytochrome RPA1025 2 COG5274 CYB5, Cytochrome b involved in lipid metabolism Energy production and conversion / Lipid metabolism 39933482 Common - hypothetical protein RPA0405 17 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 39934968 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg9 (56% identity) RPA1899 19 COG5437 COG5437, Predicted secreted protein Function unknown 39935923 Common - hypothetical protein RPA2858 3 None None None 39937051 Common galE1 UDP-galactose 4-epimerase RPA3990 231 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 39935358 Common - hypothetical protein RPA2289 10 COG4105 ComL, DNA uptake lipoprotein General function prediction only 39936740 Common - putative exporter protein, cpaC RPA3678 137 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 39934170 Common - Beta-lactamase-like RPA1095 157 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39936820 Common hpcD putative 5-carboxymethyl-2-hydroxymuconate isomerase RPA3759 30 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 39937435 Nonpathogen - hypothetical protein RPA4375 5 None None None 39935499 Common - response regulator receiver (CheY-like protein) RPA2433 96 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39934292 Common - carboxypeptidase RPA1217 124 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 39935696 Common aapM-2 polar amino acid ABC transport system protein, aapM-2 RPA2630 180 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 39935157 Common cobJ precorrin 3 methylase RPA2088 119 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 39937551 Common - hypothetical protein RPA4491 81 None None None 39934394 Common - probable transcriptional regulator, AraC family RPA1321 144 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39934821 Common - branched-chain amino acid transport system ATP-binding protein RPA1752 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935103 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA2034 121 None None None 39936844 Common - Glycosyl transferase, family 39 RPA3783 36 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39933494 Nonpathogen - hypothetical protein RPA0417 4 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 39933284 Nonpathogen - hypothetical protein RPA0207 9 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 39936100 Common - hypothetical protein RPA3037 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 39936685 Common - GCN5-related N-acetyltransferase RPA3623 92 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 39937341 Nonpathogen - hypothetical protein RPA4281 16 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39933240 Common proB gamma-glutamyl kinase RPA0163 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 39936795 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase RPA3734 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 39937491 Common - Peptidase M23/M37 RPA4431 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 39935474 Nonpathogen - hypothetical protein RPA2407 3 None None None 39936925 Nonpathogen - hypothetical protein RPA3864 3 None None None 39933289 Common - ErfK/YbiS/YcfS/YnhG RPA0212 93 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39935712 Common - putative ABC transporter oligopeptide-binding protein RPA2646 190 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39935612 Common - FKBP-type peptidyl-prolyl cis-trans isomerase RPA2546 144 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 39933207 Common - transcriptional regulator, LysR family RPA0130 172 COG0583 LysR, Transcriptional regulator Transcription 39934450 Common nifH nitrogenase reductase RPA1376 73 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39934724 Common - putative oxido-reductase RPA1654 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 39936664 Nonpathogen - hypothetical protein RPA3602 2 None None None 39937821 Common - possible cation efflux pump RPA4763 163 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 39937026 Common - putative phenylpropionate transporter RPA3965 81 None None None 39933367 Nonpathogen - hypothetical protein RPA0290 1 None None None 39937409 Nonpathogen - hypothetical protein RPA4349 3 None None None 39937040 Common - putative NADH-dependent dehydrogenase RPA3979 186 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 39933200 Common - possible KTN NAD-binding domain involved with K+ transport RPA0123 77 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 39933756 Common - hypothetical protein RPA0679 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 39933345 Common - putative Lon family ATP-dependent protease RPA0268 113 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 39935536 Common - Protein of unknown function, HesB/YadR/YfhF RPA2470 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 39935906 Common - response regulator receiver (CheY-like protein) RPA2839 55 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 39934337 Nonpathogen - hypothetical protein RPA1262 2 None None None 39936117 Common - possible transcriptional regulator, Crp/Fnr family RPA3054 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39935456 Common - hypothetical protein RPA2387 5 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39935578 Common - putative lipid kinase RPA2512 121 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 39934839 Common - hypothetical protein RPA1770 118 COG2855 COG2855, Predicted membrane protein Function unknown 39934815 Common - transcriptional regulator, LysR family RPA1746 190 COG0583 LysR, Transcriptional regulator Transcription 39933140 Common - hypothetical protein RPA0060 24 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 39934408 Common - RNA polymerase ECF-type sigma factor, possible FecI RPA1334 59 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39934606 Nonpathogen - hypothetical protein RPA1534 2 None None None 39933531 Common - hypothetical protein RPA0454 26 None None None 39937338 Nonpathogen - hypothetical protein RPA4278 1 None None None 39934138 Common - hypothetical protein RPA1063 22 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 39936300 Common rpsN 30S ribosomal protein S14 RPA3237 163 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 39933436 Common - hypothetical protein RPA0359 44 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 39935517 Common - putative N-acetylmuramoyl-L-alanine amidase RPA2451 176 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 39937700 Common cbbA fructose-1,6-bisphosphate aldolase RPA4642 174 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 39937104 Common - putative branched-chain amino acid transport system permease protein RPA4044 143 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39933447 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS domains RPA0370 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39934503 Common - putative coenzyme F390 synthetase RPA1429 121 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 39934935 Common - hypothetical protein RPA1866 25 COG5402 COG5402, Uncharacterized conserved protein Function unknown 39933415 Common - hypothetical protein RPA0338 34 COG5470 COG5470, Uncharacterized conserved protein Function unknown 39936110 Common - putative exopolyphosphatase RPA3047 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 39933090 Common - possible glutamate uptake transcriptional regulator, AsnC family RPA0010 152 COG1522 Lrp, Transcriptional regulators Transcription 39935952 Common secG preprotein translocase subunit SecG RPA2887 40 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 39937288 Nonpathogen - hypothetical protein RPA4228 1 None None None 39934985 Common feuQ two-component sensor histidine kinase, FeuQ RPA1916 203 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39936509 Common - 3-hydroxyisobutyrate dehydrogenase RPA3446 174 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 39936310 Common rplB 50S ribosomal protein L2 RPA3247 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 39937420 Common - DUF152 RPA4360 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 39934378 Common - putative transglycolase RPA1303 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 39933354 Common - hypothetical protein RPA0277 9 COG2361 COG2361, Uncharacterized conserved protein Function unknown 39933778 Common - putative acetyltransferase (virginiamycin, streptogramin A, chloramphenicol) RPA0701 73 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 39935865 Common BenE probable Benzoate membrane transport protein RPA2798 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 39936107 Common - hypothetical protein RPA3044 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 39936364 Common - lipid-transfer protein RPA3301 157 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39936756 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase RPA3694 138 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 39936093 Nonpathogen - hypothetical protein RPA3030 3 None None None 39934927 Common - sensor histidine kinase with a PAS domain RPA1858 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39935085 Common - possible methyltransferase related protein RPA2016 38 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 39937000 Common - hypothetical protein RPA3939 65 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 39936152 Common RadA DNA repair protein RadA RPA3089 216 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 39935257 Nonpathogen - hypothetical protein RPA2188 4 None None None 39936785 Common ilvK possible high-affinity leucine-isoleucine-valine transport system; periplasmic binding protein RPA3724 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39933164 Common mutM formamidopyrimidine-DNA glycosylase RPA0084 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 39936864 Common - carbon-monoxide dehydrogenase small subunit RPA3803 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 39935127 Common - hypothetical protein RPA2058 22 COG4309 COG4309, Uncharacterized conserved protein Function unknown 39936702 Common - Glycoside hydrolase, family 15 RPA3640 71 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 39937484 Common - Beta-lactamase-like RPA4424 79 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39934180 Common - possible OpgC protein, require for succinylation of osmoregulated periplasmic glucans RPA1105 36 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 39936779 Common - transcriptional regulator, IclR family RPA3718 88 COG1414 IclR, Transcriptional regulator Transcription 39933395 Common - putative Mg(2+) chelatase family protein RPA0318 198 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 39935295 Common trbF1 putative conjugal transfer protein trbF RPA2226 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 39937490 Common - putative TonB-dependent receptor RPA4430 109 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 39936096 Common argE acetylornithine deacetylase RPA3033 213 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 39936324 Common hmrR heavy metal resistance transcriptional regulator Hmrr, MerR family RPA3261 141 COG0789 SoxR, Predicted transcriptional regulators Transcription 39936644 Common - hypothetical protein RPA3582 46 None None None 39934527 Common norE putative denitrification protein NorE RPA1453 36 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 39937281 Common - putative permease RPA4221 136 COG0628 PerM, Predicted permease General function prediction only 39933635 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase RPA0558 176 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 39936772 Common nirA ferredoxin-nitrite reductase RPA3710 160 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 39933867 Common - hypothetical protein RPA0790 14 None None None 39936266 Common pccB propionyl-CoA carboxylase beta chain RPA3203 212 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 39935959 Nonpathogen - hypothetical protein RPA2894 8 None None None 39935484 Common - putative 3-ketoacyl-CoA reductase RPA2417 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935319 Common - hypothetical protein RPA2250 9 None None None 39935971 Common gltX glutamyl-tRNA synthetase RPA2906 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 39933858 Nonpathogen - putative cytochrome c552 precursor RPA0781 3 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 39937713 Common fucA L-fuculose phosphate aldolase RPA4655 141 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 39936816 Common hpcH putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase RPA3755 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 39937058 Nonpathogen - hypothetical protein RPA3997 1 None None None 39934687 Common - ErfK/YbiS/YcfS/YnhG RPA1617 75 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39937037 Common - putative nodulation protein RPA3976 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 39937324 Common nuoA2 NADH-ubiquinone dehydrogenase chain A RPA4264 89 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 39934056 Common - sensor histidine kinase with multiple PAS and a response regulator receiver domain RPA0981 215 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39936138 Common fabD acyl-carrier-protein S-malonyltransferase RPA3075 207 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 39935377 Common - possible periplasmic iron siderophore binding protein of ABC transporter RPA2308 108 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 39937391 Common aatA aspartate aminotransferase RPA4331 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 39936978 Common - possible acetolactate synthase large subunit RPA3917 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39935937 Nonpathogen - hypothetical protein RPA2872 1 None None None 39937846 Common ugpB2 putative sn-glycerol 3-phosphate transport system; periplasmic binding protein RPA4788 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 39933998 Common - hypothetical protein RPA0921 160 COG1360 MotB, Flagellar motor protein Cell motility and secretion 39936401 Common - possible Condensation domain, peptide synthetase RPA3338 63 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39934804 Common - putative amidotransferase, subunit A RPA1734 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39934531 Common norQ regulatory protein NorQ, probable ATPase RPA1457 79 COG0714 COG0714, MoxR-like ATPases General function prediction only 39937311 Common oahs O-acetylhomoserine sulfhydrylase RPA4251 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 39936131 Nonpathogen - hypothetical protein RPA3068 3 None None None 39934832 Common - acyl-CoA synthetase RPA1763 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936486 Common - hypothetical protein RPA3423 16 None None None 39934650 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase RPA1580 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 39937412 Common - hypothetical protein RPA4352 58 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39933759 Common - possible ABC transporter ATP-binding component, membrane bound RPA0682 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 39935758 Common rnpO DNA-directed RNA polymerase subunit omega RPA2692 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 39934484 Common - possible taurine transport system protein RPA1410 60 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39935524 Common - putative cytochrome b561 RPA2458 89 COG3038 CybB, Cytochrome B561 Energy production and conversion 39935566 Common - possible amidase RPA2500 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39934177 Common ruvB Holliday junction DNA helicase B RPA1102 232 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 39935013 Common oxlT possible oxalate/formate antiporter RPA1944 81 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936353 Common - possible transcriptional regulator, TetR family RPA3290 38 COG1309 AcrR, Transcriptional regulator Transcription 39934847 Common - amidase RPA1778 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39936614 Common - putative short-chain dehydrogenase/reductase RPA3552 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39937214 Nonpathogen - hypothetical protein RPA4154 3 None None None 39933740 Common badM putative transcriptional regulator, badM RPA0663 124 COG1959 COG1959, Predicted transcriptional regulator Transcription 39937876 Nonpathogen - hypothetical protein RPA4818 16 COG3212 COG3212, Predicted membrane protein Function unknown 39935409 Common - hypothetical protein RPA2340 31 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 39936030 Common yjeF hypothetical protein RPA2965 213 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 39937656 Common - possible acyl-CoA dehydrogenase RPA4598 43 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934319 Nonpathogen - hypothetical protein RPA1244 12 None None None 39936828 Common paaB phenylacetic acid degradation protein paaB RPA3767 36 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 39935034 Common - putative Adenylate/Guanylate cyclase RPA1965 86 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 39933449 Common - transcriptional regulators, AsnC family RPA0372 153 COG1522 Lrp, Transcriptional regulators Transcription 39935138 Nonpathogen - hypothetical protein RPA2069 7 None None None 39934042 Common hupF hydrogenase expression/formation protein hupF RPA0967 17 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 39935462 Common prpB putative carboxyphosphonoenolpyruvate phosphonomutase RPA2395 131 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 39935381 Common - hypothetical protein RPA2312 4 None None None 39936338 Common secE preprotein translocase subunit SecE RPA3275 49 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 39935142 Common - putative oxidoreductase RPA2073 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39933855 Nonpathogen - hypothetical protein RPA0778 1 None None None 39936210 Common clpA endopeptidase Clp: ATP-binding chain A RPA3147 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 39933504 Common - enoyl-(acyl carrier protein) reductase RPA0427 225 COG0623 FabI, Enoyl- acyl-carrier-protein 39934980 Nonpathogen - Nickel-dependent hydrogenase b-type cytochrome subunit RPA1911 2 COG3038 CybB, Cytochrome B561 Energy production and conversion 39935825 Common - possible cytochrome c oxidase assembly protein RPA2758 45 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 39934433 Common - possible transglycosylase RPA1359 125 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 39933402 Common - hypothetical protein RPA0325 31 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935246 Common - DUF404 RPA2177 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 39936052 Common - hypothetical protein RPA2987 60 COG0657 Aes, Esterase/lipase Lipid metabolism 39933456 Common pfkB putative 6-phosphofructokinase RPA0379 122 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 39936732 Common - putative ATP-dependent RNA helicase RPA3670 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 39936892 Common - hypothetical protein RPA3831 24 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 39937507 Nonpathogen - hypothetical protein RPA4447 1 None None None 39935916 Common - DUF173 RPA2851 128 COG1354 COG1354, Uncharacterized conserved protein Function unknown 39933293 Common sdhB succinate dehydrogenase iron-sulfur subunit RPA0216 196 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 39934733 Common hpaD putative 3,4-dihydroxyphenylacetate 2,3-dioxygenase RPA1663 29 COG3384 COG3384, Uncharacterized conserved protein Function unknown 39935855 Common - possible methyltransferase RPA2788 40 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 39933383 Common hslU ATP-dependent protease ATP-binding subunit RPA0306 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 39934284 Common - hypothetical protein RPA1209 26 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 39934691 Common - hypothetical protein RPA1621 5 None None None 39934421 Common - RNA polymerase ECF-type sigma factor, possible FecI RPA1347 50 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39935221 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS domain RPA2152 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39935650 Common - possible glyoxalase RPA2584 65 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 39934123 Nonpathogen - hypothetical protein RPA1048 2 None None None 39934758 Common - GCN5-related N-acetyltransferase RPA1688 44 COG3153 COG3153, Predicted acetyltransferase General function prediction only 39934999 Common - two-component transcriptional regulator, winged helix family RPA1930 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39933606 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) RPA0529 176 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 39935508 Common - putative outer membrane protein RPA2442 82 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 39935548 Common - probable epimerase/dehydratase RPA2482 135 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39936605 Common - possible multidrug resistance efflux pump RPA3543 160 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39937564 Common - putative short-chain alcohol dehydrogenase RPA4506 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934193 Common TolR putative tolR protein, uptake of enterochelin; tonB-dependent uptake of B colicins RPA1118 130 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 39936722 Common ureC urease subunit alpha RPA3660 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 39936217 Common - possible chromosome partitioning protein ParA RPA3154 106 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 39936661 Nonpathogen - hypothetical protein RPA3599 1 None None None 39934002 Nonpathogen - hypothetical protein RPA0925 1 None None None 39936146 Nonpathogen - hypothetical protein RPA3083 1 None None None 39933911 Nonpathogen CoxF putative CoxF RPA0834 1 None None None 39935211 Common - putative fatty-acid--CoA ligase RPA2142 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936497 Common - Universal stress protein (Usp) RPA3434 100 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39935601 Common waaG putative UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase RPA2535 123 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39937253 Common pyk pyruvate kinase RPA4193 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 39936031 Common glnB nitrogen regulatory protein P-II RPA2966 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 39937422 Common ribP ribose-phosphate pyrophosphokinase RPA4362 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 39935745 Common - putative transport system ATP-binding protein RPA2679 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39934644 Common - DUF477 RPA1574 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 39933127 Common - hypothetical protein RPA0047 22 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 39933527 Common - transcriptional regulator, FUR family; probable FUR protein RPA0450 188 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 39935096 Common - ATPase:Protein of unknown function DUF87 RPA2027 81 COG0433 COG0433, Predicted ATPase General function prediction only 39936299 Common rpsH 30S ribosomal protein S8 RPA3236 235 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 39934533 Common - hypothetical protein RPA1461 8 None None None 39937389 Common - hypothetical protein RPA4329 11 None None None 39934409 Common - probable FecR, iron siderophore sensor protein RPA1335 46 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 161610768 Common - glutamyl-Q tRNA(Asp) synthetase RPA4754 243 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 39936563 Common - hypothetical protein RPA3501 32 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 39935400 Common ggt2 possible gamma-glutamyltranspeptidase RPA2331 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 39933649 Common regS two component sensor histidine kinase, RegS RPA0572 188 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39936762 Common - Bacterial luciferase RPA3700 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 39937695 Nonpathogen - hypothetical protein RPA4637 1 None None None 39934084 Common - possible cytochrome P450 RPA1009 70 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 39935064 Common - hypothetical protein RPA1995 10 None None None 39936204 Common - possible VirR protein RPA3141 95 COG1720 COG1720, Uncharacterized conserved protein Function unknown 39935816 Nonpathogen - hypothetical protein RPA2749 12 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 39935624 Common - hypothetical protein RPA2558 24 COG3952 COG3952, Predicted membrane protein Function unknown 39935948 Nonpathogen - hypothetical protein RPA2883 1 None None None 39933487 Common - GCN5-related N-acetyltransferase RPA0410 27 COG0456 RimI, Acetyltransferases General function prediction only 39934991 Common cycL CycL cytochrome C-type biogenesis protein RPA1922 87 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 39937272 Common - hypothetical protein RPA4212 52 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 39937382 Common - response regulator receiver (CheY-like protein) RPA4322 51 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39936836 Common - putative RND efflux transporter RPA3775 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39936690 Common - amidase RPA3628 215 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39936290 Common rpsK 30S ribosomal protein S11 RPA3227 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 39937644 Common - possible Glycosyl transferase group 1 RPA4586 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39933146 Common ihfB integration host factor subunit beta RPA0066 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 39934459 Common ptxB putative phosphonate transport system substrate-binding protein RPA1385 95 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 39933213 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA0136 79 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39937455 Common - transcriptional regulator, XRE family RPA4395 54 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 39935312 Common - possible transcriptional regulator, XRE family RPA2243 35 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 39936851 Common - putative efflux protein RPA3790 127 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39937402 Common - hypothetical protein RPA4342 13 None None None 39934143 Common - Glycine cleavage T protein (aminomethyl transferase) RPA1068 124 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 39937266 Common - D-beta-hydroxybutyrate dehydrogenase RPA4206 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935216 Nonpathogen - hypothetical protein RPA2147 12 None None None 39936191 Common - putative transport protein RPA3128 64 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39934266 Common - putative RNA methyltransferase RPA1191 159 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 39935556 Common - hypothetical protein RPA2490 53 COG2808 PaiB, Transcriptional regulator Transcription 39934572 Nonpathogen - hypothetical protein RPA1500 8 None None None 39934215 Common groEL chaperonin GroEL RPA1140 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 39935303 Common - hypothetical protein RPA2234 23 None None None 39935842 Common - thymidylate kinase RPA2775 207 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 39937885 Common - hypothetical protein RPA4827 9 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 39937485 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase RPA4425 174 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 39933830 Common cysN putative CysN/CysC bifunctional enzyme, ATP-sulfurylase large subunit and adenylyl sulfate kinase RPA0753 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 39935686 Common - hypothetical protein RPA2620 6 None None None 39933577 Common - Heat shock protein DnaJ, N-terminal RPA0500 48 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 39935640 Common - possible RND efflux transporter RPA2574 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39936471 Common - Nitroreductase family RPA3408 79 COG0778 NfnB, Nitroreductase Energy production and conversion 39936859 Common - hypothetical protein RPA3798 113 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 39935804 Common - hypothetical protein RPA2737 28 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 39935449 Common - probable tonB dependent iron siderophore receptor RPA2380 36 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39936935 Common - hypothetical protein RPA3874 6 None None None 39934780 Common - putative acyl-CoA dehydrogenase RPA1710 153 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934076 Common - hypothetical protein RPA1001 19 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 39936537 Common - putative transposase RPA3475 47 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 39936221 Nonpathogen - hypothetical protein RPA3158 4 None None None 39937086 Common - possible ABC transporter,ATP binding protein RPA4026 248 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39937600 Nonpathogen - hypothetical protein RPA4542 1 None None None 39933966 Common hspD small heat shock protein RPA0889 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 39934708 Common flhA flagellar biosynthesis protein A RPA1638 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 39934873 Common - hypothetical protein RPA1804 46 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39937287 Common ureG urease accessory protein UreG RPA4227 150 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 39933985 Nonpathogen - hypothetical protein RPA0908 1 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 39934671 Common - possible transcriptional regulator, MarR family RPA1601 16 COG1846 MarR, Transcriptional regulators Transcription 39935396 Common - putative ABC transporter oligopeptide-binding protein RPA2327 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39933835 Common - putative oligopeptide ABC transporter, ATP-binding component RPA0758 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 39935201 Nonpathogen - hypothetical protein RPA2132 6 None None None 161610773 Common psd phosphatidylserine decarboxylase RPA2006 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 39933312 Common leuD isopropylmalate isomerase small subunit RPA0235 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 39933718 Common fliD possible flagellar hook-associated protein 2 (FliD, filament cap protein) RPA0641 79 COG1345 FliD, Flagellar capping protein Cell motility and secretion 39935367 Nonpathogen - hypothetical protein RPA2298 7 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 39937815 Common - possible outer membrane receptor for iron transport RPA4757 40 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39933689 Common - possible sugar kinase RPA0612 88 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 39934894 Nonpathogen - hypothetical protein RPA1825 6 None None None 39933936 Common - ABC transporter, permease protein RPA0859 183 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 39933849 Common - Pentapeptide repeat RPA0772 78 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 39937772 Common - hypothetical protein RPA4714 14 None None None 39935218 Common - putative hydroxyquinol 1,2-dioxygenase RPA2149 52 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 39934882 Common - RNA polymerase sigma factor RPA1813 105 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39936341 Common exbB putative exbB, uptake of enterochelin; tonB-dependent uptake of B colicins RPA3278 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39933837 Common - putative oligopeptide ABC transporter, permease component RPA0760 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39937791 Common plsC putative 1-acyl-SN-glycerol-3-phosphate acyltransferase RPA4733 125 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 39935208 Common - possible glutathione S-transferase RPA2139 83 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39937636 Common - Basic membrane lipoprotein RPA4578 95 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 39935917 Common - putative sugar hydrolase RPA2852 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 39937290 Nonpathogen - hypothetical protein RPA4230 3 None None None 39935936 Common - probable RhtB family transporter, amino acid efflux RPA2871 111 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 39936535 Common ucpA putative oxidoreductase RPA3473 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936010 Common nuoF1 NADH-ubiquinone dehydrogenase chain F RPA2945 165 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 39934268 Common - cytochrome b/c1 precursor RPA1193 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 161610775 Common fliF flagellar MS-ring protein RPA1264 127 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 39933309 Common - putative carbonic anhydrase RPA0232 152 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 39936286 Common - putative alginate lyase RPA3223 160 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39935394 Common - acetylornithine deacetylase RPA2325 208 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 39937736 Common - possible outer membrane protein precursor OprF RPA4678 120 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 39937859 Common - MFS permease family RPA4801 53 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936460 Nonpathogen - hypothetical protein RPA3397 2 None None None 39937121 Common - putative glycosyltransferase RPA4061 93 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39937774 Common modB molybdate transport system permease protein RPA4716 210 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 39935591 Common cspA2 cold shock DNA binding protein RPA2525 158 COG1278 CspC, Cold shock proteins Transcription 39936224 Common yafB putative aldose reductase RPA3161 174 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 39936272 Nonpathogen - hypothetical protein RPA3209 1 None None None 39933600 Common - hypothetical protein RPA0523 40 COG4291 COG4291, Predicted membrane protein Function unknown 39935922 Common - hypothetical protein RPA2857 17 None None None 39934091 Common petA ubiquinol-cytochrome-c reductase, Rieske iron-sulfur protein RPA1016 112 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 39937255 Common - putative hydrolase RPA4195 116 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39933276 Common - putative phosphinothricin acetyltransferase RPA0199 100 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 39936875 Nonpathogen - Calcium-binding EF-hand RPA3814 2 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 39935185 Common - hypothetical protein RPA2116 9 None None None 39933251 Common invA2 dinucleoside polyphosphate hydrolase RPA0174 114 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 39937162 Common - transcriptional regulator, MarR family RPA4102 125 COG1846 MarR, Transcriptional regulators Transcription 39934261 Common - hypothetical protein RPA1186 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 39934082 Common mhpB possible 2,3-dihydroxyphenylpropionate 1,2-dioxygenase RPA1007 32 COG3384 COG3384, Uncharacterized conserved protein Function unknown 39934538 Common - amidase RPA1466 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39936388 Nonpathogen - hypothetical protein RPA3325 1 None None None 39935175 Common - hypothetical protein RPA2106 46 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39934252 Common - 4-oxalocrotonate tautomerase RPA1177 4 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 39936525 Common - hypothetical protein RPA3463 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39933723 Nonpathogen - hypothetical protein RPA0646 1 None None None 39937465 Common - hypothetical protein RPA4405 25 COG5477 COG5477, Predicted small integral membrane protein Function unknown 39934765 Common - CUPIN domain:transcriptional regulator, AraC family RPA1695 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39934795 Common - bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase RPA1725 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39937850 Common - RNA polymerase sigma factor RPA4792 170 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39936469 Common thrS threonyl-tRNA synthetase RPA3406 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39933323 Common - PilT protein, N-terminal RPA0246 15 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 39934493 Common - possible transport system permease protein RPA1419 68 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39933731 Common badH 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase RPA0654 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 39933610 Common - possible transmembrane protein RPA0533 33 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 39935761 Common acpS 4'-phosphopantetheinyl transferase RPA2695 136 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 39937640 Common galE2 UDP-galactose 4-epimerase RPA4582 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 39933713 Nonpathogen - hypothetical protein RPA0636 3 None None None 39937500 Common tyrC cyclohexadienyl dehydrogenase RPA4440 178 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 39934800 Common - possible hydrolase RPA1730 59 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 39933549 Common - OmpA-like transmembrane domain RPA0472 27 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39935420 Common - transcriptional regulator, AsnC family RPA2351 157 COG1522 Lrp, Transcriptional regulators Transcription 39936186 Nonpathogen - hypothetical protein RPA3123 1 None None None 39937216 Common - 3-oxoadipate CoA-transferase subunit A RPA4156 107 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 39933197 Common rmlA glucose-1-phosphate thymidylyltransferase RPA0120 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 39933806 Common - hypothetical protein RPA0729 17 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39937437 Common ileS isoleucyl-tRNA synthetase RPA4377 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39933224 Common - transcriptional regulator, ModE family RPA0147 90 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 39936933 Nonpathogen - hypothetical protein RPA3872 5 None None None 39933324 Common romA putative outer membrane protein RPA0247 93 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 39937875 Common - two-component transcriptional regulator, winged helix family RPA4817 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39937317 Common nuoI2 NADH dehydrogenase subunit I RPA4257 190 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 39937262 Common - methyl-accepting chemotaxis sensory transducer RPA4202 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39937634 Common - putative permease protein of sugar ABC transporter RPA4576 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 39935052 Common gor putative glutathione reductase RPA1983 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 39934944 Common - possible uncharacterized iron-regulated membrane protein RPA1875 25 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 39937067 Nonpathogen - hypothetical protein RPA4007 2 None None None 39937128 Nonpathogen - hypothetical protein RPA4068 4 None None None 39933532 Common trpS tryptophanyl-tRNA synthetase RPA0455 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39934074 Common PA5115 hypothetical protein RPA0999 55 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 39937322 Common nuoCD bifunctional NADH:ubiquinone oxidoreductase subunit C/D RPA4262 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 39935067 Nonpathogen - hypothetical protein RPA1998 2 None None None 39934857 Common - possible 4-hydroxybenzoyl-CoA thioesterase RPA1788 25 COG0824 FcbC, Predicted thioesterase General function prediction only 39933654 Common - possible penicillin-binding protein RPA0577 203 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 39934106 Common - transcriptional regulator, MarR family; N-acetyltransferase RPA1031 69 COG1846 MarR, Transcriptional regulators Transcription 39937614 Common - possible TrapT family, dctP subunit, C4-dicarboxylate periplasmic binding protein RPA4556 86 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 39933242 Common nadD nicotinic acid mononucleotide adenyltransferase RPA0165 112 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 39936449 Common - possible amidohydrolase RPA3386 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 39933896 Common - hypothetical protein RPA0819 21 None None None 39934272 Common - hypothetical protein RPA1197 16 None None None 39935348 Nonpathogen - hypothetical protein RPA2279 1 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 39935963 Common - Haloacid dehalogenase-like hydrolase RPA2898 69 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 39934093 Common - hypothetical protein RPA1018 39 None None None 39935423 Common nifB2 putative nitrogenase iron-molybdenum cofactor biosynthesis protein NifB RPA2354 65 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 39936895 Common idh isocitrate dehydrogenase RPA3834 61 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 39937686 Common hesB Protein of unknown function, HesB/YadR/YfhF RPA4628 108 COG0316 IscA, Uncharacterized conserved protein Function unknown 39936956 Common - hypothetical protein RPA3895 14 COG3334 COG3334, Uncharacterized conserved protein Function unknown 39934908 Common folB putative dihydroneopterin aldolase RPA1839 83 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 39935721 Common - beta-(1-3)-glucosyl transferase RPA2655 138 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39937025 Common - putative muconate cycloisomerase RPA3964 103 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 39933899 Common gshA gamma-glutamylcysteine synthetase RPA0822 55 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 39935009 Common - putative quinone oxidoreductase RPA1940 197 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39935043 Common - MRP protein(ATP/GTP-binding protein) homolog RPA1974 230 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 39933970 Common - hypothetical protein RPA0893 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 39933506 Common katG catalase/peroxidase RPA0429 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 39937169 Nonpathogen - hypothetical protein RPA4109 4 None None None 39935775 Nonpathogen - hypothetical membrane protein RPA2708a 2 None None None 39936949 Common flgB flagellar basal body rod protein FlgB RPA3888 42 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 39937334 Common - hypothetical protein RPA4274 7 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 39934663 Common - Thioesterase superfamily RPA1593 21 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39933404 Common hemN2 coproporphyrinogen III oxidase RPA0327 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 39935910 Common serS seryl-tRNA synthetase RPA2845 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 39937366 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4306 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39934161 Common csgG possible curli production assembly/transport component csgg precursor RPA1086 14 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 39933463 Common - Ku domain RPA0386 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 39934234 Common lpxK putative tetraacyldisaccharide 4'-kinase RPA1159 128 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 39934320 Nonpathogen - hypothetical protein RPA1245 5 None None None 39936201 Common - putative glycerophosphoryl diester phosphodiesterase RPA3138 78 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 39936901 Common - putative hydroxamate-type ferrisiderophore receptor RPA3840 121 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39936017 Common nuoA1 NADH dehydrogenase subunit A RPA2952 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 39934867 Common - putative periplasmic binding protein for ABC transporter for branched chain amino acids RPA1798 114 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39936358 Common - possible branched-chain amino acid ABC transporter, permease protein RPA3295 146 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934961 Common - probable large terminase, Rhodobacter capsulatus GTA orfg2 homologue RPA1892 25 COG5323 COG5323, Uncharacterized conserved protein Function unknown 39936517 Common - putative transmembrane transport protein, MFS family RPA3454 92 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 39934501 Common - putative ABC transporter, permease protein RPA1427 143 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 39936277 Nonpathogen - hypothetical protein RPA3214 1 None None None 39933454 Common - hypothetical protein RPA0377 51 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39934731 Common - DUF156 RPA1661 102 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 39937589 Common hisD histidinol dehydrogenase RPA4531 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 39933585 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha RPA0508 178 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 39934274 Common - enoyl-(acyl carrier protein) reductase RPA1199 229 COG0623 FabI, Enoyl- acyl-carrier-protein 39935672 Common tgt queuine tRNA-ribosyltransferase RPA2606 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 39933353 Common - PAP/25A core domain:DNA polymerase, beta-like region RPA0276 35 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 39933640 Nonpathogen - hypothetical protein RPA0563 8 COG1289 COG1289, Predicted membrane protein Function unknown 39937197 Nonpathogen - hypothetical protein RPA4137 11 COG5490 COG5490, Uncharacterized conserved protein Function unknown 39935851 Common - possible nodulin-related protein RPA2784 74 COG1814 COG1814, Uncharacterized membrane protein Function unknown 39934742 Common - hypothetical protein RPA1672 35 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 39935634 Common - cysteine synthase A RPA2568 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 39937577 Nonpathogen - hypothetical protein RPA4519 3 None None None 39935740 Common - quinone oxidoreductase RPA2674 179 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39936160 Common - hypothetical protein RPA3097 19 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 39937362 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4302 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39936440 Common - 3-oxoacyl-acyl carrier protein reductase RPA3377 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936857 Common - transcriptional regulator, LysR family RPA3796 177 COG0583 LysR, Transcriptional regulator Transcription 39933106 Common - Major Facilitator Superfamily (MFS) transporter RPA0026 73 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 39934026 Common matE2 putative multidrug efflux protein (NorM) RPA0949 171 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 39936581 Common recN putative DNA repair protein RecN RPA3519 193 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 39933647 Common - hypothetical protein RPA0570 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 39934375 Common - possible restriction system protein RPA1300 25 COG1715 Mrr, Restriction endonuclease Defense mechanisms 39934313 Common - enoyl-CoA hydratase RPA1238 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936050 Common - conserved unknownl protein RPA2985 76 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39937580 Common cbbY Haloacid dehalogenase-like hydrolase RPA4522 163 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 39936009 Common nuoG1 NADH dehydrogenase subunit G RPA2944 193 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 39936246 Nonpathogen - hypothetical protein RPA3183 3 None None None 39937585 Common maf Maf-like protein RPA4527 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 39937299 Nonpathogen - hypothetical protein RPA4239 9 None None None 39936368 Common paaG2 enoyl-CoA hydratase/isomerase family RPA3305 139 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39933922 Common atpE F0F1 ATP synthase subunit C RPA0845 7 None None None 39937095 Common - possible ABC transport system permease protein RPA4035 109 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39933903 Common - DUF433 RPA0826 24 COG2442 COG2442, Uncharacterized conserved protein Function unknown 39934035 Common - putative acyl-CoA dehydrogenase RPA0958 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934837 Nonpathogen - hypothetical protein RPA1768 1 None None None 39935119 Nonpathogen - hypothetical protein RPA2050 5 None None None 39936433 Nonpathogen - hypothetical protein RPA3370 1 None None None 39937229 Common - Bacterial regulatory protein, GntR family RPA4169 98 COG1802 GntR, Transcriptional regulators Transcription 39934529 Common norC nitric-oxide reductase subunit C RPA1455 36 None None None 39933558 Common - putative acyl-CoA dehydrogenase RPA0481 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934228 Common ubiA prenyltransferase RPA1153 168 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 39933376 Common maf1 putative maf protein RPA0299 178 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 39934118 Common - possible protease SohB RPA1043 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 39937554 Common - hypothetical protein RPA4494 8 None None None 39935981 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase RPA2916 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 39935255 Common - possible 3-oxo-(acyl) acyl carrier protein reductase RPA2186 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39937664 Common nifW nitrogenase stabilizing/protective protein RPA4606 22 None None None 39933380 Common - hypothetical protein RPA0303 46 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 39934312 Common - possible acyl-CoA dehydrogenase RPA1237 132 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39933802 Common sugE possible chaperone RPA0725 146 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 39933842 Common - putative outer membrane receptor for iron transport RPA0765 82 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39934439 Common - putative sulfatase RPA1365 90 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 39935074 Common - ABC transporter, fused ATPase and permease domain RPA2005 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 39936919 Nonpathogen - hypothetical protein RPA3858 2 None None None 39936988 Common - possible phosphoheptose isomerase RPA3927 117 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 39935736 Common - probable transporter RPA2670 90 COG0679 COG0679, Predicted permeases General function prediction only 39936745 Common - hypothetical protein RPA3683 67 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 39935276 Common - putative recombinase RPA2207 53 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 39937723 Common leuA 2-isopropylmalate synthase RPA4665 209 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 39937052 Common - putative ABC transporter ATP-binding protein RPA3991 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 39936717 Common - probable alcohol dehydrogenase RPA3655 196 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 39933111 Nonpathogen - hypothetical protein RPA0031 3 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 39933952 Common hemH ferrochelatase RPA0875 160 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 39937746 Common - possible inner mitochondrial membrane protein Sco1p RPA4688 106 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 39934879 Common - putative outer membrane protein RPA1810 133 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39934845 Common - possible lipid transfer protein RPA1776 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39933790 Common - hypothetical protein RPA0713 19 COG5469 COG5469, Predicted metal-binding protein Function unknown 39934616 Common bchM Mg-protoporphyrin IX methyl transferase RPA1546 77 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 39934232 Common - hypothetical protein RPA1157 24 None None None 39935796 Common nusB transcription antitermination protein NusB RPA2729 171 COG0781 NusB, Transcription termination factor Transcription 39934915 Common - hypothetical protein RPA1846 12 None None None 39936642 Common - Integrase, catalytic domain RPA3580 126 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 39935957 Common moaC molybdenum cofactor biosynthesis protein C RPA2892 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 39937838 Common pstS1 periplasmic phosphate-binding protein, (PBP) RPA4780 132 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 39934087 Common - possible integral membrane protein RPA1012 31 COG0730 COG0730, Predicted permeases General function prediction only 39936597 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase RPA3535 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 39934990 Common cycK CycK cytochrome c-type synthesis protein RPA1921 133 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 39934365 Common - possible plasmid maintenance system antidote protein RPA1290 66 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 39937171 Nonpathogen - hypothetical protein RPA4111 1 None None None 39935123 Common - possible outer membrane protein precursor CzcC RPA2054 89 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39934294 Nonpathogen - hypothetical protein RPA1219 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 39937539 Common czcA3 putative heavy metal cation efflux system protein RPA4479 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 39933668 Common glnD PII uridylyl-transferase RPA0591 126 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 39934017 Common - fructose-bisphosphate aldolase RPA0940 44 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 39935086 Common - lipid A biosynthesis lauroyl acyltransferase RPA2017 101 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 39934329 Common - putative ATP-binding component of ABC transporter RPA1254 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39937515 Nonpathogen - hypothetical protein RPA4455 3 None None None 39937670 Common fdxB ferredoxin 2[4Fe-4S] III, fdxB RPA4612 30 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 39934245 Common pgsA possible CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase RPA1170 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 39937755 Common ligJ 4-oxalomesaconate hydratase RPA4697 35 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 39934809 Common - possible branched-chain amino acid transport system permease protein RPA1740 143 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39936659 Common - hypothetical protein RPA3597 48 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 39934747 Common cheW3 chemotaxis signal transduction/oligomerization protein CheW3 RPA1677 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 39935836 Common - putative diguanylate cyclase (GGDEF) RPA2769 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39935872 Common nthA nitrile hydratase alpha subunit RPA2805 21 None None None 39935112 Common - putative ABC transporter, periplasmic substrate-binding protein RPA2043 47 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39933310 Common - putative Citrate lyase beta chain (acyl lyase subunit) (citE) RPA0233 112 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 39934790 Common - hypothetical protein RPA1720 50 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 39935583 Common - hypothetical protein RPA2517 37 COG3247 HdeD, Uncharacterized conserved protein Function unknown 39935355 Nonpathogen - hypothetical protein RPA2286 1 None None None 39934072 Common - possible transcriptional regulator, ArsR family RPA0997 155 COG0640 ArsR, Predicted transcriptional regulators Transcription 39935751 Common - hypothetical protein RPA2685 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 39935160 Nonpathogen - hypothetical protein RPA2091 3 None None None 39934257 Common - hypothetical protein RPA1182 34 COG5426 COG5426, Uncharacterized membrane protein Function unknown 39936484 Common - hypothetical protein RPA3421 23 COG3672 COG3672, Predicted periplasmic protein Function unknown 39934308 Common - putative branched-chain amino acid transport system ATP-binding protein RPA1233 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936112 Common - hypothetical protein RPA3049 55 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 39937679 Common - hypothetical protein RPA4621 18 None None None 39936557 Common - possible TctA subunit of the Tripartite Tricarboxylate Transport(TTT) Family RPA3495 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 39937143 Common - hypothetical protein RPA4083 3 None None None 39933934 Common - possible outer membrane protein RPA0857 31 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39937308 Common fixJ response regulator FixJ RPA4248 222 COG4566 TtrR, Response regulator Signal transduction mechanisms 39937220 Common - polyamine ABC transporter, ATP-binding protein RPA4160 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 39934448 Common vnfA Sigma-54 dependent, Vanadium nitrogenase transcriptional regulator, VnfA RPA1374 173 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 39936403 Common - peptide synthetase (fragment) RPA3340 207 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39933173 Common - transcriptional regulator, TetR family RPA0093 123 COG1309 AcrR, Transcriptional regulator Transcription 39933259 Common xerC site-specific tyrosine recombinase XerC RPA0182 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 39934625 Common cbbR cbb operon transcriptional regulator CbbR, LysR family RPA1555 193 COG0583 LysR, Transcriptional regulator Transcription 39936910 Common - glycine cleavage system protein H RPA3849 184 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 39934802 Common - possible cytochrome P450 RPA1732 86 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 39935978 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase RPA2913 161 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 39934561 Common - two-component transcriptional regulator, LuxR family RPA1489 206 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 39937016 Common - hypothetical protein RPA3955 6 COG0824 FcbC, Predicted thioesterase General function prediction only 39934568 Common - possible monooxygenase RPA1496 61 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 39934830 Common - enoyl-CoA hydratase RPA1761 185 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39937596 Common - hypothetical protein RPA4538 2 None None None 39933666 Common - possible acyl-CoA dehydrogenase RPA0589 128 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934204 Common - possible transcriptional regulator, TetR family RPA1129 13 COG1309 AcrR, Transcriptional regulator Transcription 39935328 Common arsH possible arsH protein RPA2259 55 COG0431 COG0431, Predicted flavoprotein General function prediction only 39936025 Common clpX ATP-dependent protease ATP-binding subunit RPA2960 230 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 39933659 Common - hypothetical protein RPA0582 21 COG5470 COG5470, Uncharacterized conserved protein Function unknown 39934471 Common - putative sugar ABC transporter, permease protein RPA1397 152 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 39935882 Common - possible outer membrane protein RPA2815 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39937532 Common - putative c-type cytochrome biogenesis protein RPA4472 89 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 39933979 Common - Glyoxalase/Bleomycin resistance protein/dioxygenase domain RPA0902 28 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 39937443 Nonpathogen - hypothetical protein RPA4383 6 None None None 39936083 Common mexE RND multidrug efflux membrane fusion protein MexE precursor RPA3020 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39937843 Common - Polysaccharide deacetylase RPA4785 38 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 39937327 Common - acyl-CoA synthetase RPA4267 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39937527 Common soxY2 sulfur oxidation protein SoxY RPA4467 39 COG5501 COG5501, Predicted secreted protein Function unknown 39934922 Common - putative short-chain dehydrogenase RPA1853 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935181 Common nrtA putative nitrate transporter component, nrtA RPA2112 98 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39936670 Common - PilT protein, N-terminal RPA3608 16 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 39934891 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA1822 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39935989 Common dnaE DNA polymerase III subunit alpha RPA2924 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 39937866 Common - possible hexuronate transporter RPA4808 84 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39937547 Common - DSBA oxidoreductase:Tat pathway signal RPA4487 92 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 39935663 Common hfq RNA-binding protein Hfq RPA2597 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 39937007 Nonpathogen - hypothetical protein RPA3946 1 None None None 39934557 Common nnrU putative NnrU protein RPA1485 25 COG4094 COG4094, Predicted membrane protein Function unknown 39935668 Common - peptidyl prolyl cis-trans isomerase RPA2602 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 39935335 Common gst1 putative glutathione S-transferase RPA2266 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39937808 Common etfB electron transfer flavoprotein beta chain, (ETFSS) RPA4750 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 39934577 Common - putative porphobilinogen deaminase RPA1505 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 39935146 Common - probable transcriptional regulator, Crp/Fnr family RPA2077 61 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39935193 Common - tonB dependent iron siderophore receptor RPA2124 123 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39937390 Common - hypothetical protein RPA4330 11 None None None 39936801 Common sqhC squalene-hopene-cyclase RPA3740 39 COG1657 SqhC, Squalene cyclase Lipid metabolism 39934542 Common - putative dipeptide ABC transporter RPA1470 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 39936255 Common - MaoC-like dehydratase:Asparaginase/glutaminase RPA3192 32 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39937625 Common pta bifunctional enoyl-CoA hydratase/phosphate acetyltransferase RPA4567 155 COG0280 Pta, Phosphotransacetylase Energy production and conversion 39933616 Common - transcriptional regulator, MarR family RPA0539 19 COG1846 MarR, Transcriptional regulators Transcription 39935893 Common - hypothetical protein RPA2826 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 39933775 Common phnE2 possible PhnE protein, phosphonate ABC transporter, permease component RPA0698 74 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 39933944 Common - Endoribonuclease L-PSP RPA0867 166 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 39935437 Common - pseudogene-two-component transcriptional regulator, winged helix family RPA2368 124 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39934353 Common - GatB/Yqey RPA1278 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 39936305 Common rpmC 50S ribosomal protein L29 RPA3242 174 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 39936888 Nonpathogen - hypothetical protein RPA3827 14 COG4006 COG4006, Uncharacterized protein conserved in archaea Function unknown 39933235 Common rplU 50S ribosomal protein L21 RPA0158 130 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 39936964 Common mexD3 RND multidrug efflux transporter MexD RPA3903 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39934518 Common - putative oligopeptide binding protein precursor RPA1444 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 39936264 Common - formate/nitrate transporter RPA3201 94 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 39934770 Common - amidase RPA1700 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39935414 Nonpathogen - hypothetical protein RPA2345 1 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 39937096 Common - possible branched-chain amino acid ABC transporter, permease protein RPA4036 136 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934391 Nonpathogen - hypothetical protein RPA1316 1 None None None 39934413 Common - RNA polymerase ECF-type sigma factor, possible FecI RPA1339 51 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39935299 Common trbE1 conjugal transfer protein trbE RPA2230 61 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 39936869 Common livG ATP-binding component of ABC transporter (putative for high-affinity branched-chain amino acid transport) RPA3808 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936349 Common - possible phosphoglycerate mutase RPA3286 43 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 39936076 Nonpathogen pucAd light harvesting protein B-800-850, alpha chain D (antenna pigment protein, alpha chain D) (LH II-D alpha) RPA3012 7 None None None 39937762 Nonpathogen - hypothetical protein RPA4704 1 None None None 39934782 Common - putative enoyl-CoA hydratase RPA1712 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39933347 Common ubiH 2-octaprenyl-6-methoxyphenyl hydroxylase RPA0270 126 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 39937074 Nonpathogen - hypothetical protein RPA4014 3 None None None 39935022 Common - possible FusB/FusC Fusaric Acid resistance pump RPA1953 53 COG1289 COG1289, Predicted membrane protein Function unknown 39933474 Common - hypothetical protein RPA0397 32 None None None 39934604 Common bchP geranylgeranyl reductase RPA1532 50 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 39933130 Common rpoN RNA polymerase factor sigma-54 RPA0050 143 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 39936159 Nonpathogen - hypothetical protein RPA3096 3 None None None 39936181 Common pyr dihydroorotase RPA3118 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 39936507 Common - transcriptional regulator, GntR family RPA3444 124 COG1802 GntR, Transcriptional regulators Transcription 39933551 Nonpathogen - hypothetical protein RPA0474 2 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 39935090 Common - 3-hydroxymyristoyl-acyl carrier protein dehydratase RPA2021 184 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 39936383 Nonpathogen - hypothetical protein RPA3320 2 None None None 39933567 Common - hypothetical protein RPA0490 24 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 39934717 Common - putative esterase RPA1647 96 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39934525 Nonpathogen - hypothetical protein RPA1451 3 None None None 39936018 Common hupA possible DNA-binding protein hu-alpha (NS2) (HU-2) RPA2953 195 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 39935509 Common - probable antioxidant protein RPA2443 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 39933238 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA0161 80 COG2962 RarD, Predicted permeases General function prediction only 39934718 Common - membrane permeases, predicted cation efflux pumps RPA1648 169 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39933574 Common - GCN5-related N-acetyltransferase RPA0497 31 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 39935673 Common - possible transcriptional regulator, XRE family, CUPIN domain RPA2607 126 COG1396 HipB, Predicted transcriptional regulators Transcription 39933913 Common coxC cytochrome c oxidase subunit III RPA0836 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 39934314 Common exbB1 putative biopolymer transport protein ExbB RPA1239 120 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39935826 Common - possible transcriptional regulator, TetR family RPA2759 12 COG1309 AcrR, Transcriptional regulator Transcription 39935863 Common glyA2 serine hydroxymethyltransferase RPA2796 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 39936862 Common - MoxR-like ATPase RPA3801 102 COG0714 COG0714, MoxR-like ATPases General function prediction only 39937638 Common - hypothetical protein RPA4580 71 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 39937347 Common - hypothetical protein RPA4287 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39935850 Nonpathogen - hypothetical protein RPA2783 1 None None None 39937800 Nonpathogen - hypothetical protein RPA4742 3 None None None 39936407 Common - possible oxidoreductase RPA3344 63 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 39936995 Common - sensor histidine kinase with a PAC motif and a response regulator receiver domain RPA3934 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39934195 Common tolB translocation protein TolB RPA1120 161 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 39933648 Common regR two-component transcriptional regulator RegR, Fis family RPA0571 199 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 39935857 Common phaC putative monovalent cation/H+ antiporter subunit C RPA2790 82 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 39936662 Common bfr bacterioferritin RPA3600 110 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 39934130 Common nadA quinolinate synthetase RPA1055 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 39935614 Common - hypothetical protein RPA2548 29 COG2966 COG2966, Uncharacterized conserved protein Function unknown 39936686 Common - possible gluconolactonase precursor RPA3624 74 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 39936480 Common - Lipocalin-related protein and Bos/Can/Equ allergen:Rhomboid-like protein RPA3417 15 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 39934414 Common - probable FecR, iron siderophore sensor protein RPA1340 45 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 39935738 Common - possible phosphatidylcholine synthase RPA2672 23 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 39936448 Common nrtC2 putative nitrate transport system ATP-binding protein RPA3385 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39933389 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase RPA0312 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 39936974 Nonpathogen flaF flagellar biosynthesis regulatory protein FlaF RPA3913 8 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 39935515 Nonpathogen - hypothetical protein RPA2449 2 None None None 39934452 Common vnfD nitrogenase vanadium-iron protein alpha chain RPA1378 57 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39936289 Common rpoA DNA-directed RNA polymerase subunit alpha RPA3226 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 39937072 Common - hypothetical protein RPA4012 83 COG2378 COG2378, Predicted transcriptional regulator Transcription 39936169 Common - putative signal transduction histidine kinase with PAS/PAC domain RPA3106 97 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39936472 Common - possible metal-dependent hydrolase RPA3409 96 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 39937817 Common - glycosyl hydrolase, family 13 RPA4759 171 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 39935047 Common moaA molybdenum cofactor biosynthesis protein A RPA1978 199 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 39936457 Common - hypothetical protein RPA3394 181 COG0759 COG0759, Uncharacterized conserved protein Function unknown 39934885 Common - putative outer membrane receptor for iron transport RPA1816 117 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39934806 Common - short chain dehydrogenase RPA1737 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 39935998 Common - hypothetical protein RPA2933 21 COG5454 COG5454, Predicted secreted protein Function unknown 39935501 Common accC acetyl-CoA carboxylase biotin carboxylase subunit RPA2435 230 COG0439 AccC, Biotin carboxylase Lipid metabolism 39937325 Common ndvA putative beta-1,2-glucan ABC export system ATP-binding protein ndvA RPA4265 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 39936495 Common - hypothetical protein RPA3432 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 39937548 Common - Excinuclease ABC, C subunit, N-terminal RPA4488 43 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 39934683 Common - putative cytochrome P-450 RPA1613 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 39936116 Common cspA3 cold shock DNA binding protein RPA3053 176 COG1278 CspC, Cold shock proteins Transcription 39937871 Common - possible branched chain amino acid periplasmic binding protein of ABC transporter RPA4813 90 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935847 Common - acyl-CoA synthetase RPA2780 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39933956 Common kpsF CBS domain:Sugar isomerase (SIS):KpsF/GutQ family protein RPA0879 155 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 39934732 Nonpathogen - hypothetical protein RPA1662 3 None None None 39936003 Common nuoM1 NADH dehydrogenase subunit M RPA2938 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 39936292 Common adk adenylate kinase RPA3229 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 39935154 Nonpathogen CbiG cobalamin biosynthesis protein G; CbiG RPA2085 6 None None None 39937146 Common - probable permease of ABC transporter RPA4086 107 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 39936764 Common metH B12-dependent methionine synthase RPA3702 175 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 39935895 Common - hypothetical protein RPA2828 39 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 39937856 Common - putative acyl-CoA dehydrogenase RPA4798 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39935551 Common aqpZ aquaporin Z RPA2485 125 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 39937649 Common metY homocysteine synthase RPA4591 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 39936451 Common - hypothetical protein RPA3388 16 None None None 39933722 Common flgE flagellar hook protein FlgE RPA0645 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 39933819 Common - hypothetical protein RPA0742 46 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 39934941 Common thcC Rhodocoxin RPA1872 98 COG0633 Fdx, Ferredoxin Energy production and conversion 39934962 Nonpathogen - hypothetical protein RPA1893 1 None None None 39937878 Common mtnA methylthioribose-1-phosphate isomerase RPA4820 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 39936410 Common - putative glycosyltransferase RPA3347 10 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 39933209 Common - ABC sulfonate transport system, permease protein RPA0132 98 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39934347 Common - Transglutaminase-like domain RPA1272 84 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 39935707 Common - putative ABC transporter oligopeptide-binding protein RPA2641 205 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39936427 Common rrm1 putative rRNA methylase RPA3364 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 39934196 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) RPA1121 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39933638 Common - hypothetical protein RPA0561 13 None None None 39937810 Common rbn1 putative ribonuclease RNAse BN (RBN) transmembrane protein RPA4752 93 COG1295 Rbn, Predicted membrane protein Function unknown 39934698 Common cheW2 chemotaxis signal transduction/oligomerization protein CheW2 RPA1628 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 39936735 Common - hypothetical protein RPA3673 15 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39934167 Common - Carboxymuconolactone decarboxylase RPA1092 75 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 39934423 Common - Hemolysin activation/secretion protein RPA1349 29 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 39934624 Common hemA 5-aminolevulinate synthase RPA1554 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 39933502 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase RPA0425 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 39934431 Common - hypothetical protein RPA1357 4 None None None 39933499 Common - 2-hydroxyacid dehydrogenase RPA0422 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 39935464 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase RPA2397 137 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 39937212 Common fbpA periplasmic iron binding protein FbpA precursor RPA4152 118 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 39936162 Common - hypothetical protein RPA3099 34 COG4094 COG4094, Predicted membrane protein Function unknown 39935365 Nonpathogen - hypothetical protein RPA2296 3 None None None 39936192 Common rpmG 50S ribosomal protein L33 RPA3129 123 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 39933202 Common - possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA RPA0125 79 COG1409 Icc, Predicted phosphohydrolases General function prediction only 39935240 Nonpathogen - hypothetical protein RPA2171 1 None None None 39937414 Common - translation-associated GTPase RPA4354 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 39934560 Common - L-carnitine dehydratase/bile acid-inducible protein F RPA1488 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39935719 Nonpathogen pucAa light harvesting protein B-800-850, alpha chain A (antenna pigment protein, alpha chain A) (LH II-A alpha) RPA2653 7 None None None 39935988 Common - hypothetical protein RPA2923 14 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 39934117 Common - hypothetical protein RPA1042 50 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 39936632 Common - two-component transcriptional regulator, winged helix family RPA3570 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39937250 Common - hypothetical protein RPA4190 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 39933092 Nonpathogen rdxS possible fixS RPA0012 1 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 39937630 Common htrA/degQ/degS putative serine protease htrA/degQ/degS family RPA4572 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39935383 Common - cytochrome c556 RPA2314 16 COG3909 COG3909, Cytochrome c556 Energy production and conversion 39936917 Nonpathogen - hypothetical protein RPA3856 1 None None None 39933453 Common pimt1 putative L-isoaspartyl protein carboxyl methyltransferase RPA0376 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 39933792 Common cobW putative cobalamin synthesis protein cobW RPA0715 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 39935702 Common NifD2 possible nitrogenase molybdenum-iron protein alpha chain (nitrogenase component I) (dinitrogenase) RPA2636 61 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39937567 Common - possible TrapT family, fused dctQ-M subunits, C4-dicarboxylate transport RPA4509 126 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 39937071 Common - possible serine protease/outer membrane autotransporter RPA4011 116 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 39935370 Common - probable transcriptional regulator, AraC family RPA2301 69 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39935442 Common mexB RND multidrug efflux transporter MexB RPA2372 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39934901 Nonpathogen - hypothetical protein RPA1832 3 None None None 39937085 Common - putative branched-chain amino acid ABC transport system ATP-binding protein RPA4025 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936938 Nonpathogen - hypothetical protein RPA3877 1 None None None 39935382 Nonpathogen - hypothetical protein RPA2313 2 None None None 39935969 Common - possible DNA uptake protein, ComEC RPA2904 81 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 39933935 Common - ABC transporter, ATP-binding protein RPA0858 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 39935040 Common - hypothetical protein RPA1971 35 COG3313 COG3313, Predicted Fe-S protein General function prediction only 39936461 Common - possible arsenite permease RPA3398 121 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 39933525 Common miaB tRNA-i(6)A37 modification enzyme MiaB RPA0448 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 39937672 Common - DUF269 RPA4614 25 None None None 39936033 Common - probable transcriptional regulator, TetR family RPA2968 87 COG1309 AcrR, Transcriptional regulator Transcription 39936607 Common - hypothetical protein RPA3545 41 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 39936568 Common uvrD DNA helicase II RPA3506 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 39936565 Common - putative D-lactate dehydrogenase, oxidoreductase RPA3503 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 39935982 Common cdsA Phosphatidate cytidylyltransferase RPA2917 213 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 39935710 Common - putative ABC transporter permease protein RPA2644 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39934081 Common - possible protocatechuate 4,5-dioxygenase small subunit (AB035121) RPA1006 13 None None None 39935962 Common motB2 possible chemotaxis protein MotB2 RPA2897 92 COG1360 MotB, Flagellar motor protein Cell motility and secretion 39937254 Common osmC osmotically inducible protein OsmC RPA4194 83 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 39936693 Common - putative glucose dehydrogenase RPA3631 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934265 Common - hypothetical protein RPA1190 151 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 39934535 Common ilvD2 dihydroxy-acid dehydratase RPA1463 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 39935171 Common - hypothetical protein RPA2102 16 COG2259 COG2259, Predicted membrane protein Function unknown 39937270 Nonpathogen - hypothetical protein RPA4210 1 None None None 39936098 Nonpathogen - hypothetical protein RPA3035 1 None None None 39934182 Common - possible transcriptional regulator, TetR family RPA1107 26 COG1309 AcrR, Transcriptional regulator Transcription 39937705 Common kdgR probable transcriptional regulator KdgR, IclR family RPA4647 123 COG1414 IclR, Transcriptional regulator Transcription 39936099 Nonpathogen - hypothetical protein RPA3036 1 None None None 39935094 Common - possible MgtC Mg2+ transport protein RPA2025 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 39935941 Common mdoG glucan biosynthesis protein G RPA2876 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 39936832 Nonpathogen - hypothetical protein RPA3771 3 None None None 39937796 Common - response regulator receiver (CheY-like protein) RPA4738 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39935087 Common - alcohol dehydrogenase RPA2018 215 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39936306 Common rplP 50S ribosomal protein L16 RPA3243 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 39937118 Common - Glycosyl transferase, family 2:Mitochondrial substrate carrier RPA4058 16 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39937487 Common ogt1 putative methylated-DNA-protein-cystein methyltransferase RPA4427 216 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 39933417 Common pgm1 phosphoglyceromutase RPA0340 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 39937688 Common nifB nitrogen fixation protein nifB RPA4630 69 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 39933269 Common mdh malate dehydrogenase RPA0192 200 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 39937283 Common - two-component response regulator RPA4223 91 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 39937159 Nonpathogen - hypothetical protein RPA4099 1 None None None 39934521 Common - putative oligopeptide ABC transporter (permease) RPA1447 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 45429962 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg10 RPA1900 9 None None None 39935754 Common smpB SsrA-binding protein RPA2688 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 39937024 Common - putative permease of ABC transporter RPA3963 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 39934810 Common - possible branched-chain amino acid transport system substrate-binding protein RPA1741 132 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934144 Common pyrC dihydroorotase RPA1069 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 39934058 Common - possible phthalate dioxygenase RPA0983 73 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 39937522 Common - Lipocalin-related protein and Bos/Can/Equ allergen RPA4462 21 None None None 39937478 Common - hypothetical protein RPA4418 31 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 39936312 Common rplD 50S ribosomal protein L4 RPA3249 217 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 39934178 Common - Thioesterase superfamily:4-hydroxybenzoyl-CoA thioesterase RPA1103 119 COG0824 FcbC, Predicted thioesterase General function prediction only 39933992 Common - putative NADPH quinone oxidoreductase RPA0915 200 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39934159 Common csgB possible minor curlin subunit precursor (fimbrin sef17 minor subunit). RPA1084 12 None None None 39937616 Common - possible dehydratase, MaoC family RPA4558 93 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39937393 Common - hypothetical protein RPA4333 125 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 39937293 Common - Cyclic nucleotide regulated K+ channel RPA4233 153 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39936280 Common - possible branched-chain amino acid transport system substrate-binding protein RPA3217 82 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39936773 Common - sulfite reductase RPA3711 99 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 39933683 Common prfA peptide chain release factor 1 RPA0606 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 39934078 Common - putative acyl-CoA synthase RPA1003 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936780 Common ilvG putative high-affinity branched-chain amino acid transport system ATP-binding protein RPA3719 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39937572 Common - possible alkaline phosphatase D precursor RPA4514 58 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 39933296 Common sdhC succinate dehydrogenase membrane anchor/cytochrome b subunit RPA0219 72 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 39933243 Common - Iojap-related protein RPA0166 199 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 39936818 Common - transcriptional regulator, MarR family RPA3757 57 COG1846 MarR, Transcriptional regulators Transcription 39933694 Common recR recombination protein RecR RPA0617 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 39936101 Common - hypothetical protein RPA3038 33 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39936374 Common - glycosyl hydrolase RPA3311 170 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 39935080 Common - puative potassium uptake protein Kup RPA2011 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 39934892 Common - TonB dependent receptor RPA1823 49 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39935379 Common - putative iron ABC transporter ATP-binding protein RPA2310 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 39934552 Common cpdA putative ICC protein RPA1480 102 COG1409 Icc, Predicted phosphohydrolases General function prediction only 39937416 Common ctc 50S ribosomal protein L25/general stress protein Ctc RPA4356 167 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 39934656 Common - putative short-chain dehydrogenase/reductase RPA1586 211 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935645 Nonpathogen - hypothetical protein RPA2579 2 None None None 39937238 Common - hypothetical protein RPA4178 12 None None None 39933546 Common AtsC putative sulfate ester transporter; ATP-binding component. RPA0469 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39933886 Common - transcriptional regulator, LysR family RPA0809 175 COG0583 LysR, Transcriptional regulator Transcription 39933485 Common bipA conserved GTPase RPA0408 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 39937830 Common argF ornithine carbamoyltransferase RPA4772 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 39937770 Common - TPR repeat RPA4712 41 COG5616 COG5616, Predicted integral membrane protein Function unknown 39933419 Common - hypothetical protein RPA0342 21 COG5488 COG5488, Integral membrane protein Function unknown 39935860 Common phaF putative monovalent cation/H+ antiporter subunit F RPA2793 73 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 39936810 Common eutB ethanolamine ammonia-lyase large subunit RPA3749 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 39937183 Common trbC2 conjugal transfer protein trbC RPA4123 22 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 39934386 Common - possible 4-carboxymuconolactone decarboxylase RPA1311 77 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 39934934 Common - hypothetical protein RPA1865 10 COG5436 COG5436, Predicted integral membrane protein Function unknown 39935407 Nonpathogen - hypothetical protein RPA2338 2 None None None 39936769 Common - possible nitrate transporter component, nrtA RPA3707 81 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39937745 Common - possible Glycosyl transferase RPA4687 98 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39935249 Common - hypothetical protein RPA2180 12 None None None 161610767 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein RPA4773 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 39936144 Nonpathogen - hypothetical protein RPA3081 3 COG5373 COG5373, Predicted membrane protein Function unknown 39935564 Common - possible ABC transporter, permease protein RPA2498 178 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39937404 Nonpathogen - hypothetical protein RPA4344 2 None None None 39933604 Nonpathogen - hypothetical protein RPA0527 6 None None None 39934543 Common - putative dipeptide ABC transporter (permease) RPA1471 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39933176 Common - putative multidrug-efflux transport protein RPA0096 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39937097 Common - putative ABC transport system ATP-binding protein RPA4037 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935286 Common - hypothetical protein RPA2217 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 39935234 Common groES co-chaperonin GroES RPA2165 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 39936876 Common cbbE ribulose-5-phosphate-3-epimerase RPA3815 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 39935576 Common - hypothetical protein RPA2510 16 COG1289 COG1289, Predicted membrane protein Function unknown 39933412 Common - putative phospholipid N-methyltransferase RPA0335 42 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 39933866 Common - putative serine-glyoxylate aminotransferase RPA0789 154 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 39936530 Common - putative permease protein of sugar ABC transporter RPA3468 198 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 39933445 Common rluD possible pseudouridine synthase RPA0368 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 39937387 Nonpathogen - transcriptional regulator, XRE family RPA4327 12 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 39935466 Common cobN cobaltochelatase RPA2399 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 39935111 Common - putative ABC transporter, permease protein RPA2042 150 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39936175 Common - 2-nitropropane dioxygenase RPA3112 99 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 39933407 Common hrcA heat-inducible transcription repressor RPA0330 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 39934508 Nonpathogen - hypothetical protein RPA1434 7 None None None 39936720 Common ureF possible urease accessory protein UreF RPA3658 75 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 39936478 Common - probable transcriptional regulator, TetR family RPA3415 79 COG1309 AcrR, Transcriptional regulator Transcription 39935493 Common - Serine protease, trypsin family RPA2427 220 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39937710 Common - possible CoA transferase, subunit B RPA4652 25 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 39935693 Common - putative carboxylesterase RPA2627 63 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 39937525 Common soxB sulfur/thiosulfate oxidation protein SoxB RPA4465 130 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 39935471 Common - probable transcriptional regulator, AraC family RPA2404 94 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39934172 Common - hypothetical protein RPA1097 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 39933286 Common ftsY putative cell division protein FtsY RPA0209 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 39935698 Common - ABC transport permease protein, possibly for nitrate RPA2632 181 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39935135 Common nosX putative nosX RPA2066 132 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 39937245 Common - putative oligoendopeptidase F RPA4185 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 39934846 Common - DUF35 RPA1777 61 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 39934225 Common hisZ ATP phosphoribosyltransferase regulatory subunit RPA1150 98 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 39934899 Common - hypothetical protein RPA1830 21 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 39937105 Common - possible branched-chain amino acid ABC transport system substrate-binding protein RPA4045 52 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39933788 Common - Nitroreductase family RPA0711 96 COG0778 NfnB, Nitroreductase Energy production and conversion 39936151 Nonpathogen - hypothetical protein RPA3088 12 COG1433 COG1433, Uncharacterized conserved protein Function unknown 39934336 Common - FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal RPA1261 151 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 39936133 Common - hypothetical protein RPA3070 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 39934833 Common - putative 2, 4-dienoyl-CoA reductase (NADPH) RPA1764 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935820 Common - hypothetical protein RPA2753 15 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 39936623 Common - transcriptional regulator, ArsR family RPA3561 94 COG0640 ArsR, Predicted transcriptional regulators Transcription 39936590 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase RPA3528 201 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 39933337 Nonpathogen - possible photosynthesis gene regulator, AppA/PpaA family RPA0260 5 None None None 39937339 Nonpathogen - hypothetical protein RPA4279 1 None None None 39933375 Common - hypothetical protein RPA0298 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 39933409 Nonpathogen - hypothetical protein RPA0332 7 None None None 39936701 Common cof Cof-subfamily: Cof-like hydrolase RPA3639 91 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 39934473 Common - putative transport system ATP-binding protein RPA1399 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 39934396 Nonpathogen - hypothetical protein RPA1323 1 None None None 39937516 Nonpathogen - hypothetical protein RPA4456 1 None None None 39935251 Common - putative glutathione S-transferase RPA2182 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39933874 Common uraI dihydroorotate dehydrogenase 2 RPA0797 229 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 39934467 Common - hypothetical protein RPA1393 34 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 39933612 Common hrpB putative ATP-dependent helicase RPA0535 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 39936853 Common - putative diguanylate cyclase (GGDEF) RPA3792 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39936213 Common - possible D-alanyl-D-alanine carboxypeptidase RPA3150 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 39934150 Common - DUF159 RPA1075 107 COG2135 COG2135, Uncharacterized conserved protein Function unknown 39935976 Common lpxA UDP-N-acetylglucosamine acyltransferase RPA2911 143 COG1043 LpxA, Acyl- acyl carrier protein 39936708 Common - putative maltooligosyltrehalose trehalohydrolase RPA3646 164 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 39934859 Common - putative diguanylate cyclase (GGDEF) RPA1790 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39935604 Common - putative acyl-CoA carboxylase, beta chain RPA2538 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 39937784 Nonpathogen - hypothetical protein RPA4726 2 None None None 39935953 Common cbbJ triose-phosphate isomerase RPA2888 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 39937719 Common otsB putative trehalose-6-phosphate phophatase, biosynthetic RPA4661 81 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 39936545 Common - RND efflux transporter RPA3483 183 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39933129 Common - possible ABC transporter ATP-binding protein (in rpoN upstream) RPA0049 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 39936506 Common - possible isomerase/decarboxylase RPA3443 174 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 39936750 Common - peptide ABC transporter, ATP-binding protein RPA3688 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 39936846 Common - DUF72 RPA3785 85 COG1801 COG1801, Uncharacterized conserved protein Function unknown 39936672 Nonpathogen - hypothetical protein RPA3610 3 None None None 39935359 Common - hypothetical protein RPA2290 20 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 39933660 Common - sensor histidine kinase with PAS/PAC and Response regulator receiver domains RPA0583 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39937828 Common apaG ApaG RPA4770 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 39935352 Common - putative proteic killer suppression protein {plasmid Rts1) RPA2283 29 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 39934678 Common - Beta-lactamase RPA1608 149 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 39933480 Common - hypothetical protein RPA0403 44 COG3339 COG3339, Uncharacterized conserved protein Function unknown 39933120 Common infC translation initiation factor IF-3 RPA0040 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 39934469 Common - possible trehalose/maltose binding protein RPA1395 28 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 39936646 Nonpathogen - hypothetical protein RPA3584 1 None None None 39936787 Common - hypothetical protein RPA3726 37 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 39934827 Common - enoyl-CoA hydratase RPA1758 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39935652 Common 3mg 3-methyladenine DNA glycosylase RPA2586 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 39933262 Common dldH dihydrolipoamide dehydrogenase RPA0185 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 39936321 Common - hypothetical protein RPA3258 44 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 39934406 Common - possible phage integrase/recombinase RPA1332 72 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 39934817 Common - putative branched-chain amino acid transport system substrate-binding protein RPA1748 124 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39937150 Common - hypothetical protein RPA4090 7 COG4803 COG4803, Predicted membrane protein Function unknown 39933772 Common phnG PhnG protein, phosphonate metabolism, function unknown RPA0695 31 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 39934293 Common - putative ABC transporter periplasmic protein RPA1218 182 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39935292 Common - hypothetical protein RPA2223 15 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 39934562 Common phyB4 Bacteriophytochrome (light-regulated signal transduction histidine kinase), PhyB4 RPA1490 139 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 39937127 Nonpathogen - hypothetical protein RPA4067 1 None None None 39933257 Common rlpA1 Rare lipoprotein A RPA0180 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 39935550 Nonpathogen - hypothetical protein RPA2484 3 None None None 39934787 Nonpathogen - hypothetical protein RPA1717 2 None None None 39937372 Common - putative sensor (PAS) domain for methyl-accepting chemotaxis sensory transducer RPA4312 76 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 39937227 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS domains RPA4167 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39935440 Nonpathogen - hypothetical protein RPA2370 1 None None None 39935003 Nonpathogen - hypothetical protein RPA1934 1 None None None 39934034 Common - putative enoyl-CoA hydratase RPA0957 166 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936236 Common - hypothetical protein RPA3173 99 COG1254 AcyP, Acylphosphatases Energy production and conversion 39934217 Nonpathogen - hypothetical protein RPA1142 5 None None None 39936699 Common pgl putative 6-phosphogluconolactonase RPA3637 121 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 39933701 Common dapE succinyl-diaminopimelate desuccinylase RPA0624 205 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 39936870 Common livF ATP-binding component of ABC transporter (putatively for branched chain amino acids) RPA3809 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935844 Common metG methionyl-tRNA synthetase RPA2777 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39934301 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit alpha RPA1226 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 39937536 Nonpathogen - hypothetical protein RPA4476 9 COG1416 COG1416, Uncharacterized conserved protein Function unknown 39935148 Nonpathogen - hypothetical protein RPA2079 1 None None None 39933155 Common - hypothetical protein RPA0075 56 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 39936897 Common - Integrase, catalytic domain RPA3836 126 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 39937441 Common - hypothetical protein RPA4381 9 None None None 39936538 Common - possible energy transducer TonB RPA3476 31 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 39935870 Common - hypothetical protein RPA2803 6 None None None 39933226 Common - possible ABC-type iron-siderophore transport system ATP-binding protein RPA0149 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 39937546 Common - hypothetical protein RPA4486 29 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 39936963 Common flgH flagellar basal body L-ring protein RPA3902 102 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 39934772 Common - acyl-CoA synthetase RPA1702 217 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936833 Common - hypothetical protein RPA3772 17 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39937530 Common - DUF336 RPA4470 34 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 39936592 Common murG N-acetylglucosaminyl transferase RPA3530 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 39936158 Common engA GTP-binding protein EngA RPA3095 232 COG1160 COG1160, Predicted GTPases General function prediction only 39934483 Common - possible taurine transport system permease protein RPA1409 186 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39937446 Nonpathogen - hypothetical protein RPA4386 3 None None None 39937375 Common - hypothetical protein RPA4315 13 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39933511 Common truB tRNA pseudouridine synthase B RPA0434 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 39937627 Common - DUF344 RPA4569 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 39935666 Nonpathogen - hypothetical protein RPA2600 1 None None None 39933974 Common - hypothetical protein RPA0897 23 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 39936385 Common manC putative mannose-1-phosphate guanylyltransferase (GDP) (GDP-mannose pyrophosphorylase) (GMP) RPA3322 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 39935357 Common - Streptomyces cyclase/dehydrase RPA2288 4 COG3832 COG3832, Uncharacterized conserved protein Function unknown 39933800 Common - possible hemin ABC transporter, permease component RPA0723 187 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 39933273 Common - putative ABC transporter, ATP-binding protein RPA0196 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 39933597 Common nha possible sodium/hydrogen antiporter RPA0520 131 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 39937620 Common apbA/panE putative 2-dehydropantoate 2-reductase RPA4562 136 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 39935661 Common ntrX nitrogen assimilation regulatory protein ntrX-Response regulator RPA2595 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39937865 Common - possible branched-chain amino acid transport system substrate-binding protein RPA4807 85 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39933159 Common - sensor histidine kinase with multiple PAS domains RPA0079 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 39937099 Common - hypothetical protein RPA4039 6 None None None 39937045 Common rfaE putative ADP-heptose synthase RPA3984 112 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 39935306 Common - possible lytic transglycosylase RPA2237 143 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 39934861 Common - putative branched-chain amino acid transport system ATP-binding protein RPA1792 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39933475 Common - putative 2, 4-dienoyl-CoA reductase (NADPH) precursor RPA0398 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936711 Nonpathogen - hypothetical protein RPA3649 1 None None None 39937761 Common ligC 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase RPA4703 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 39936725 Common ureA urease subunit gamma RPA3663 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 39935195 Common - hypothetical protein RPA2126 18 COG3721 HugX, Putative heme iron utilization protein Inorganic ion transport and metabolism 39937059 Nonpathogen - hypothetical protein RPA3998 1 None None None 39936378 Common - protease RPA3315 76 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 39933977 Common - probable Rht family transporter, amino acid efflux RPA0900 108 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 39936061 Common - hypothetical protein RPA2996 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 39933919 Common - hypothetical protein RPA0842 12 None None None 39936108 Common rnd ribonuclease D RPA3045 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 39937768 Nonpathogen - hypothetical protein RPA4710 3 None None None 39934819 Common - putative branched-chain amino acid transport system permease protein RPA1750 154 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934363 Common rpoD RNA polymerase sigma factor RpoD RPA1288 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 39933905 Common - transcriptional regulator, MarR family RPA0828 75 COG1846 MarR, Transcriptional regulators Transcription 39937629 Nonpathogen - hypothetical protein RPA4571 7 None None None 39933119 Common rpmI 50S ribosomal protein L35 RPA0039 120 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 39935191 Common - coproporphyrinogen III oxidase RPA2122 202 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 39935810 Common - bacterial regulatory protein, MerR family RPA2743 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 39936182 Common - hypothetical protein RPA3119 170 COG0344 COG0344, Predicted membrane protein Function unknown 39935915 Common - hypothetical protein RPA2850 138 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 39936309 Common rpsS 30S ribosomal protein S19 RPA3246 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 39935330 Common - GMP synthetase: N-terminal fragment RPA2261 219 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 39933669 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein RPA0592 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 39934609 Common - putative heme oxygenase RPA1539 23 COG5398 COG5398, Heme oxygenase Inorganic ion transport and metabolism 39935065 Nonpathogen - hypothetical protein RPA1996 5 None None None 39936793 Common argD1 putative N-acetylornithine aminotransferase RPA3732 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 39934579 Common bchD magnesium chelatase subunit D RPA1507 57 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 39936396 Common csgG putative curli production assembly/transport component csgg precursor RPA3333 14 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 39934373 Common - 3-oxoacyl-(acyl carrier protein) synthase III RPA1298 200 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 39934016 Common - possible thiamine-phosphate pyrophosphorylase RPA0939 33 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 39933651 Common - possible ABC transporter RPA0574 18 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 39935748 Common uahA Urea amidolyase-related RPA2682 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 39934706 Common - hypothetical protein RPA1636 18 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 39937756 Common FldZ hypothetical protein RPA4698 60 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 39934497 Common - hypothetical protein RPA1423 25 None None None 39937241 Common pntA nicotinamide nucleotide transhydrogenase, subunit alpha2 RPA4181 116 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 39934812 Nonpathogen - hypothetical protein RPA1743 1 None None None 39933331 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase RPA0254 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 39933431 Common - PTS system phosphocarrier protein HPr, nitrogen regulation RPA0354 151 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 39934831 Common - putative acyl-CoA dehydrogenase RPA1762 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39933738 Common badA benzoate-CoA ligase RPA0661 223 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 39934973 Common - DUF262 RPA1904 31 COG1479 COG1479, Uncharacterized conserved protein Function unknown 39936431 Nonpathogen - hypothetical protein RPA3368 2 None None None 39934581 Common hemE uroporphyrinogen decarboxylase RPA1509 179 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 39935187 Common - putative ATP-binding protein of ABC transporter RPA2118 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 39933727 Common badK cyclohex-1-ene-1-carboxyl-CoA hydratase RPA0650 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39935350 Common - putative low-affinity phosphate transport protein RPA2281 167 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 39934636 Common - possible branched-chain amino acid transport system ATP-binding protein RPA1566 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935033 Nonpathogen - hypothetical protein RPA1964 2 COG3212 COG3212, Predicted membrane protein Function unknown 39934146 Common - hypothetical protein RPA1071 12 None None None 39935121 Common - putative phophinothricin N-acetyltransferase RPA2052 118 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 39937661 Common fixC nitrogen fixation protein,fixC RPA4603 140 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 39937201 Common - hypothetical protein RPA4141 12 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 39934003 Nonpathogen - hypothetical protein RPA0926 1 None None None 39933619 Common - hypothetical protein RPA0542 45 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 39936080 Common phyB2 Bacteriophytochrome (light-regulated signal transduction histidine kinase), PhyB2 RPA3016 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 39937537 Common - Possible membrane protein with ATP/GTP-binding site motif A (P-loop) RPA4477 19 None None None 39934168 Common ribB possible GTP cyclohydrolase II, riboflavin biosynthesis RPA1093 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 39933338 Nonpathogen - hypothetical protein RPA0261 2 None None None 39933568 Common - possible MgpS, ATP-dependent helicase RPA0491 56 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 39934255 Common - putative cylclic diguanylate phosphodiesterase (EAL) RPA1180 95 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 39933853 Common - possible gamma-glutamyltranspeptidase precursor RPA0776 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 39937725 Common coxL putative carbon-monoxide dehydrogenase large subunit RPA4667 112 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 39933545 Common - putative ATP-binding protein of ABC transporter RPA0468 111 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39935708 Common - transcriptional regulator, LysR family RPA2642 105 COG0583 LysR, Transcriptional regulator Transcription 39934610 Nonpathogen - Coenzyme B12-binding RPA1540 10 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 39935439 Nonpathogen - hypothetical protein RPA2369a 1 None None None 39933931 Common hemO 5-aminolevulinate synthase RPA0854 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 39935546 Common - hypothetical protein RPA2480 27 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 39936599 Common - hypothetical protein RPA3537 21 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 39937893 Nonpathogen - hypothetical protein RPA4835 3 None None None 39936432 Nonpathogen - hypothetical protein RPA3369 1 None None None 39937801 Common argH argininosuccinate lyase RPA4743 226 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 39937835 Common pstB phosphate ABC transporter ATP-binding protein, PstB RPA4777 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 39935166 Common cobF precorrin 6A synthase RPA2097 31 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 39933184 Common - Amidohydrolase RPA0104 93 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 39936877 Nonpathogen - hypothetical protein RPA3816 1 None None None 39937696 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4638 99 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39934541 Common gatA1 amidase RPA1469 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39936920 Nonpathogen - hypothetical protein RPA3859 1 None None None 39935741 Common - hypothetical protein RPA2675 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 39933657 Common - possible branched-chain amino acid binding protein, ABC transport system RPA0580 92 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39933958 Common - hypothetical protein RPA0881 4 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 39936588 Nonpathogen - hypothetical protein RPA3526 3 None None None 39934956 Common - possible phage protease, R. capsulatus GTA orfg4 homologue RPA1887 37 COG3740 COG3740, Phage head maturation protease General function prediction only 39936931 Common - hypothetical protein RPA3870 9 None None None 39937594 Common - cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase RPA4536 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 39935534 Common - DUF59 RPA2468 133 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 39937195 Common - GCN5-related N-acetyltransferase RPA4135 46 COG3153 COG3153, Predicted acetyltransferase General function prediction only 39935128 Nonpathogen - hypothetical protein RPA2059 3 None None None 39934065 Common phyB5 Bacteriophytochrome (light-regulated signal transduction histidine kinase), PhyB5 RPA0990 72 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 39936902 Nonpathogen - hypothetical protein RPA3841 1 None None None 39934387 Nonpathogen - hypothetical protein RPA1312 4 None None None 39933590 Common pcaF beta-ketoadipyl CoA thiolase RPA0513 168 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39937193 Common - hypothetical protein RPA4133 13 None None None 39936516 Common - enoyl-CoA hydratase RPA3453 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39934122 Common glyS glycyl-tRNA synthetase subunit beta RPA1047 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 39934024 Common - hypothetical protein RPA0947 13 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 39936044 Common - hypothetical protein RPA2979 20 None None None 39934322 Common rbn2 Ribonuclease BN RPA1247 69 COG1295 Rbn, Predicted membrane protein Function unknown 39937065 Nonpathogen - hypothetical protein RPA4004 2 None None None 39935727 Common - DUF502 RPA2661 79 COG2928 COG2928, Uncharacterized conserved protein Function unknown 161610772 Common gyrA DNA gyrase subunit A RPA2599 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 39935602 Common - putative opgC protein RPA2536 36 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 39934797 Nonpathogen - hypothetical protein RPA1727 1 None None None 39937601 Nonpathogen - hypothetical protein RPA4543 1 None None None 39936366 Common - MaoC-like dehydratase RPA3303 57 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39937157 Common - transcriptional regulator, TetR family RPA4097 46 COG1309 AcrR, Transcriptional regulator Transcription 39934323 Common - two-component transcriptional regulator, LuxR family RPA1248 223 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39935586 Nonpathogen - hypothetical protein RPA2520 1 None None None 39933947 Common - putative ornithine decarboxylase RPA0870 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 39937737 Common - possible component of multidrug efflux system RPA4679 101 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39933081 Common dnaA chromosomal replication initiation protein RPA0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 39937030 Common - Metallo-phosphoesterase RPA3969 69 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 39936243 Nonpathogen - hypothetical protein RPA3180 1 None None None 39937773 Common modC molybdate transport system ATP-binding protein RPA4715 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 39936972 Nonpathogen - hypothetical protein RPA3911 5 None None None 39934296 Nonpathogen - hypothetical protein RPA1221 1 None None None 39937360 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA4300 180 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 39933516 Common - hypothetical protein RPA0439 167 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 39934094 Common - possible NolR/HlyU transcriptional regulator, ArsR family RPA1019 165 COG0640 ArsR, Predicted transcriptional regulators Transcription 39934997 Nonpathogen - ferredoxin-like protein [2Fe-2S] RPA1928 14 COG0633 Fdx, Ferredoxin Energy production and conversion 39936526 Common - hypothetical protein RPA3464 23 None None None 39933231 Common - possible MotA/TolQ/ExbB proton channel family RPA0154 117 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39936392 Common - hypothetical protein RPA3329 63 None None None 39936975 Common flbT flagellar biosynthesis repressor FlbT RPA3914 18 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 39936269 Common - hypothetical protein RPA3206 6 None None None 39937301 Common - CBS domain RPA4241 73 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 39937582 Common - sensor histidine kinase RPA4524 197 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39936941 Common - possible glutathione S-transferase P subunit RPA3880 17 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39933204 Common - putative permease protein of sugar ABC transporter RPA0127 152 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 39933890 Common - possible permease RPA0813 51 COG0730 COG0730, Predicted permeases General function prediction only 39933340 Common - hypothetical protein RPA0263 133 COG0432 COG0432, Uncharacterized conserved protein Function unknown 39933920 Common atpF1 putative Fo ATP synthase B chain RPA0843 22 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 39937267 Common - Patatin-like phospholipase domain RPA4207 46 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 39937598 Nonpathogen - hypothetical protein RPA4540 1 None None None 39936074 Nonpathogen pucBc light harvesting protein B-800-850, beta chain C (antenna pigment protein, beta chain C) (LH II-C beta) RPA3009 7 None None None 39934380 Nonpathogen - possible flagellar hook length determination protein RPA1305 9 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 39935817 Common - probable glycosyl transferase RPA2750 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 39935055 Common nadE NAD synthetase RPA1986 233 COG0171 NadE, NAD synthase Coenzyme metabolism 39936950 Common - hypothetical protein RPA3889 4 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 39934737 Nonpathogen bchJ putative 4-vinyl protochlorophyllide reductase RPA1667 14 None None None 39934628 Common - sensor histidine kinase with multiple PAS/PAC and a response regulator receiver domain RPA1558 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39936959 Common fliL flagellar basal body-associated protein FliL RPA3898 19 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 39935459 Common - possible Rhizobactin siderophore biosynthesis protein rhbC RPA2390 41 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 39936505 Common - Putative cyclase RPA3442 63 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 39937168 Common - probable transcriptional regulator, TetR family RPA4108 81 COG1309 AcrR, Transcriptional regulator Transcription 39935938 Common - possible NADH oxidoreductase RPA2873 84 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39934267 Common - cytochrome b6-F complex iron-sulfur subunit RPA1192 105 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 39935773 Common - probable transcriptional regulator, AraC family RPA2707 75 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39935787 Common - putative glutathione S-transferase YghU RPA2720 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39935274 Common - hypothetical protein RPA2205 22 COG3311 AlpA, Predicted transcriptional regulator Transcription 39933113 Nonpathogen - hypothetical protein RPA0033 9 None None None 39937357 Common - putative aldose reductase RPA4297 196 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 39933821 Nonpathogen - putative high potential iron sulfur protein (HiPIP) RPA0744 1 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 39934210 Common - probable ABC transporter with fused ATPase and permease domains for long chain FA substrate RPA1135 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 39934419 Common - hypothetical protein RPA1345 8 None None None 39936511 Common - acyl-CoA dehydrogenase RPA3448 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39937256 Common - TPR repeat RPA4196 28 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 39935391 Common - transcriptional regulator, LysR family RPA2322 113 COG0583 LysR, Transcriptional regulator Transcription 39937748 Nonpathogen - hypothetical protein RPA4690 1 None None None 39936684 Nonpathogen - hypothetical protein RPA3622 1 None None None 39933671 Common mutT putative mutator protein mutT RPA0594 155 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 39933105 Common ggt1 gamma-glutamyltranspeptidase RPA0025 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 39934114 Common ispE possible isopentenyl monophosphate kinase RPA1039 172 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 39936547 Common - putative racemase RPA3485 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39935450 Common fecR4 probable FecR, iron siderophore sensor protein RPA2381 43 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 39935671 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase RPA2605 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 39936993 Common - probable flagellar hook protein flgE RPA3932 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 39934085 Common - Beta-lactamase-like:ATP/GTP-binding site motif A (P-loop) RPA1010 45 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 39934281 Common - aldehyde dehydrogenase RPA1206 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39936463 Nonpathogen - hypothetical protein RPA3400 1 None None None 39934590 Common crtD methoxyneurosporene dehydrogenase RPA1518 92 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39933097 Nonpathogen ccoQ cytochrome oxidase subunit, small membrane protein RPA0017 3 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 39933625 Common - hypothetical protein RPA0548 130 COG0628 PerM, Predicted permease General function prediction only 39935430 Common - putative ABC transporter, permease protein RPA2361 155 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 39937294 Common aadR anaerobic aromatic degradation regulator aadR, Crp/Fnr family RPA4234 136 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39936218 Common panC putative pantoate-beta-alanine ligase RPA3155 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 39936203 Common - probable Hit-like protein involved in cell-cycle regulation RPA3140 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 39934792 Common alkB alkylated DNA repair protein RPA1722 57 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 39933815 Common - possible L-sorbosone dehydrogenase. RPA0738 66 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 39935345 Common - putative branched-chain amino acid transport system ATP-binding protein RPA2276 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39934495 Common - possible efflux protein RPA1421 152 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39936576 Common - hypothetical protein RPA3514 177 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 39936946 Common fliQ flagellar biosynthesis protein FliQ RPA3885 27 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 39933631 Common - ureidoglycolate hydrolase RPA0554 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 39936125 Common - predicted permease RPA3062 106 COG0795 COG0795, Predicted permeases General function prediction only 39934913 Common - hypothetical protein RPA1844 137 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 39933322 Common ffh/ftsY signal recognition particle protein RPA0245 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 39935262 Common - putative ABC transporter, perplasmic binding protein, branched chain amino acids RPA2193 83 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39937872 Common - hypothetical protein RPA4814 21 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39937789 Nonpathogen - hypothetical protein RPA4731 7 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 39937004 Common - hypothetical protein RPA3943 38 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 39933387 Nonpathogen - hypothetical protein RPA0310 7 None None None 39937707 Common - probable ABC transporter permease protein RPA4649 209 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 39933329 Common - hypothetical protein RPA0252 46 COG3897 COG3897, Predicted methyltransferase General function prediction only 39935522 Common - possible bacterioferritin co-migratory protein RPA2456 209 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 39933704 Common - putative haloacid dehalogenase superfamily hydrolase RPA0627 48 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 39936807 Common - possible RND Superfamily transporter RPA3746 75 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 39934722 Common - possible flagellar basal-body rod protein FlgG RPA1652 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 39933369 Common parA chromosome partitioning protein, ParA RPA0292 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 39934745 Common - methyl-accepting chemotaxis receptor/sensory transducer with PAS domain RPA1675 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39933879 Common - ATP-dependent DNA ligase RPA0802 106 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 39933799 Common fecE putative iron(III) dicitrate ABC transporter, ATP-binding component FecE RPA0722 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 39933804 Common - S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase RPA0727 10 COG5379 BtaA, S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase Lipid metabolism 39934684 Common ivd2 isovaleryl-CoA dehydrogenase RPA1614 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934236 Common xseA exodeoxyribonuclease VII large subunit RPA1161 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 39934446 Common vnfN putative nitrogenase cofactor synthesis protein RPA1372 48 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39935428 Common - putative periplasmic protein RPA2359 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 39935322 Nonpathogen - hypothetical protein RPA2253 1 None None None 39936188 Common RNR ribonuclease R RPA3125 192 COG0557 VacB, Exoribonuclease R Transcription 39935014 Common - formyl-coenzyme A transferase RPA1945 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39936969 Nonpathogen fliX flagellar assembly regulator FliX RPA3908 9 None None None 39935763 Common - putative ribonuclease III RPA2697 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 39933906 Common ohr organic hydroperoxide resistance protein RPA0829 95 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 39935904 Common lppB Peptidoglycan-binding LysM:Peptidase M23/M37 RPA2837 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 39935688 Common - putative sulfonate transport system, ATP-binding protein. Subunit of ABC transporter RPA2622 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39933872 Common - Peptidase family S24 RPA0795 45 COG2932 COG2932, Predicted transcriptional regulator Transcription 39935045 Common - possible TrapT family, dctM subunit, glutamate transport RPA1976 129 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 39933509 Common pnp polynucleotide phosphorylase/polyadenylase RPA0432 233 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 39934595 Nonpathogen bchY bacteriochlorophyllide reductase subunit BchY RPA1523 15 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39933715 Common - hypothetical protein RPA0638 16 COG5610 COG5610, Predicted hydrolase (HAD superfamily) General function prediction only 39933175 Common - putative multidrug efflux membrane fusion protein RPA0095 136 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39935054 Nonpathogen - probable diacylglycerol kinase RPA1985 3 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 39937782 Common pyrE orotate phosphoribosyltransferase RPA4724 138 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 39933745 Common hbaE putative ABC transporter subunit, substrate-binding component RPA0668 123 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935991 Common - ATP-binding protein of ABC transporter, possibly involved in lipoprotein release RPA2926 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 39936199 Common - hypothetical protein RPA3136 19 None None None 39933245 Common - putative filament-A precursor RPA0168 153 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 39936843 Common - putative rubredoxin reductase RPA3782 216 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 39937014 Common - putative chloride channel protein RPA3953 164 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 39934412 Common - hypothetical protein RPA1338 14 None None None 39934763 Common sodB superoxide dismutase RPA1693 206 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 39933754 Common - hypothetical protein RPA0677 16 COG3396 COG3396, Uncharacterized conserved protein Function unknown 39936051 Common - probable 5-carboxymethyl-2-hydroxymuconate delta isomerase RPA2986 16 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 39933538 Common gabD1 succinate-semialdehyde dehydrogenase RPA0461 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39935141 Common - possible 3-oxoacyl-acyl carrier protein reductase RPA2072 52 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935984 Common rrf ribosome releasing factor RPA2919 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 39934587 Common - hypothetical protein RPA1515 27 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39934623 Nonpathogen - hypothetical protein RPA1553 11 None None None 39935695 Common aapQ-2 polar amino acid ABC transpor permease protein, aapQ-2 RPA2629 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 39933737 Common badG benzoyl-CoA reductase subunit RPA0660 62 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 39937505 Nonpathogen - hypothetical protein RPA4445 6 None None None 39935405 Nonpathogen - hypothetical protein RPA2336 1 None None None 39933465 Common - potassium/proton antiporter RPA0388 111 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 39933513 Common infB translation initiation factor IF-2 RPA0436 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 39935115 Common leuI 2-isopropylmalate synthase RPA2046 212 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 39933500 Common - hypothetical protein RPA0423 46 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 39935242 Common - GCN5-related N-acetyltransferase RPA2173 22 COG0456 RimI, Acetyltransferases General function prediction only 39934994 Common - putative transmembrane protein RPA1925 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936737 Nonpathogen - Flp/Fap pilin component RPA3675 3 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 39937020 Common - putative amidase RPA3959 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39933216 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA0139 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39933335 Common - hypothetical protein RPA0258 27 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 39937727 Common - putative racemase RPA4669 114 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39936225 Common - transcriptional regulator, XRE family RPA3162 44 COG2944 COG2944, Predicted transcriptional regulator Transcription 39937210 Common - hypothetical protein RPA4150 15 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 39934342 Common fliY flagellar motor switch protein RPA1267 126 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 39933377 Common coaE dephospho-CoA kinase RPA0300 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 39933314 Nonpathogen - hypothetical protein RPA0237 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 39935258 Common - possible transcriptional regulator, TetR family RPA2189 6 COG1309 AcrR, Transcriptional regulator Transcription 39936979 Common - hypothetical protein RPA3918 41 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 39934349 Common - possible Dps protein family starvation-inducible DNA-binding protein RPA1274 136 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 39935681 Common nifH2 putative nitrogenase iron protein (nitrogenase component II) (nitrogenase reductase) RPA2615 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39936041 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA2976 57 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 39933451 Common - putative Zn-containing alcohol dehydrogenase RPA0374 191 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 39937232 Nonpathogen - hypothetical protein RPA4172 1 None None None 39935743 Common - putative substrate-binding protein, subunit of ABC transporter RPA2677 95 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39935038 Common yjbN tRNA-dihydrouridine synthase A RPA1969 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 39934649 Common - L-carnitine dehydratase/bile acid-inducible protein F RPA1579 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39935571 Common glpX fructose 1,6-bisphosphatase II RPA2505 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 39935385 Common - enoyl-CoA hydratase RPA2316 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39937555 Common htpX possible protease htpX homolog RPA4495 179 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 39934485 Common - possible enoyl-CoA hydratase/isomerase RPA1411 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39934304 Common - probable aerobic phenylacetate-CoA ligase RPA1229 128 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 39935967 Common moeA molybdenum cofactor biosynthesis protein A RPA2902 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 39934537 Common - possible chloride channel RPA1465 98 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 39935324 Nonpathogen - hypothetical protein RPA2255 1 None None None 39937570 Common - possible response regulator receiver RPA4512 12 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 39935704 Common - possible oxidoreductase RPA2638 85 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 39935290 Common - hypothetical protein RPA2221 36 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 39936855 Nonpathogen - hypothetical protein RPA3794 2 None None None 39934165 Common - transcriptional regulatorn, Crp/Fnr family RPA1090 38 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39935974 Common lpxB lipid-A-disaccharide synthase RPA2909 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 39934369 Nonpathogen - hypothetical protein RPA1294 1 None None None 39937204 Nonpathogen - hypothetical protein RPA4144 11 None None None 39933942 Common - homospermidine synthase RPA0865 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 39934045 Common hupI putative rubredoxin hupI RPA0970 80 COG1773 COG1773, Rubredoxin Energy production and conversion 39933523 Common - hypothetical protein RPA0446 202 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 39933915 Common - possible surfeit 1 RPA0838 56 COG3346 COG3346, Uncharacterized conserved protein Function unknown 39935831 Common - CoA Binding Domain RPA2764 116 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 39935363 Common - probable transcriptional regulator, TetR family RPA2294 83 COG1309 AcrR, Transcriptional regulator Transcription 39937698 Nonpathogen - hypothetical protein RPA4640 1 None None None 39934633 Common - putative nitrilase RPA1563 106 COG0388 COG0388, Predicted amidohydrolase General function prediction only 39937632 Nonpathogen - hypothetical protein RPA4574 1 None None None 39933662 Common - chromate transporter RPA0585 79 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 39934695 Common cysQ putative CysQ protein RPA1625 164 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 39935654 Common - hypothetical protein RPA2588 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 39937152 Nonpathogen - hypothetical protein RPA4092 3 None None None 39937691 Common fixR2 short-chain dehydrogenase RPA4633 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935582 Nonpathogen - hypothetical protein RPA2516 2 None None None 39936347 Common - possible penicillin binding protein RPA3284 139 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 39937466 Common - sugar ABC transport system, permease component RPA4406 157 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 39933933 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA0856 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39935859 Common phaE putative monovalent cation/H+ antiporter subunit E RPA2792 63 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 39933747 Common hbaB 4-hydroxybenzoyl-CoA reductase, first of three subunits RPA0670 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 39935926 Common xthA2 exodeoxyribonuclease III RPA2861 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 39937450 Common - NUDIX hydrolase RPA4390 42 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 39937083 Common - putative branched-chain amino acid ABC transport system ATP-binding protein RPA4023 248 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936936 Nonpathogen - hypothetical protein RPA3875 10 None None None 39935514 Common dctA2 C4-dicarboxylic acid transport protein RPA2448 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 39936688 Common - hypothetical protein RPA3626 30 None None None 39933123 Common - possible glutathione S-transferase RPA0043 49 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39935807 Common plsX fatty acid/phospholipid synthesis protein RPA2740 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 39937459 Common - possible branched-chain amino acid transport system ATP-binding protein RPA4399 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39933887 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA0810 124 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 39936600 Common - Bacterial methyltransferase RPA3538 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 39933831 Common - putative signal transduction histidine kinase with PAS/PAC domains RPA0754 156 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39935268 Nonpathogen - hypothetical protein RPA2199 4 None None None 39935486 Common - putative soluble lytic murein transglycosylase precursor RPA2420 144 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 39935800 Nonpathogen - hypothetical protein RPA2733 2 None None None 39937576 Nonpathogen - hypothetical protein RPA4518 2 None None None 39937562 Common - acetyl-CoA synthetase RPA4504 218 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 39937798 Common pcaC putative 4-carboxymuconolactone decarboxylase RPA4740 89 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 39936981 Common - possible ADP-heptose synthase RPA3920 111 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 39933706 Common argB acetylglutamate kinase RPA0629 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 39935212 Common - putative acetyl/propionyl-CoA carboxylase RPA2143 145 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 39936739 Common - hypothetical protein RPA3677 20 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 39937476 Common - hypothetical protein RPA4416 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 39936489 Nonpathogen - hypothetical protein RPA3426 4 None None None 161610770 Common rplJ 50S ribosomal protein L10 RPA3270 212 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 39937173 Common - putative conjugal transfer protein trbB RPA4113 148 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 39933909 Common coxA cytochrome c oxidase subunit I RPA0832 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 39934362 Common dnaG DNA primase RPA1287 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 39936405 Common - possible glycosyl hydrolase RPA3342 14 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 39937520 Common dhsU1 putative flavocytochrome C sulfide dehydrogenase, flavoprotein subunit RPA4460 57 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 39934187 Common - DGPF domain RPA1112 45 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 39934438 Common - sulfate ester transport system ATP-binding protein RPA1364 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39934600 Common pufM photosynthetic reaction center M protein RPA1528 21 None None None 39935543 Common - possible ATP-dependent RNA helicase RPA2477 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 39936195 Common pleD response regulator PleD RPA3132 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39936304 Common rpsQ 30S ribosomal protein S17 RPA3241 218 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 39937461 Common - possible branched-chain amino acid ABC transporter, permease protein RPA4401 67 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39933981 Common - putative Mono-phosphatase RPA0904 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 39935828 Common - possible oxidoreductase RPA2761 7 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 39936474 Common - hypothetical protein RPA3411 13 None None None 39937779 Common - possible+E2677 pyruvate-flavodoxin oxidoreductase RPA4721 110 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 39933764 Common - hypothetical protein RPA0687 43 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 39936345 Common - RNA polymerase ECF-type sigma factor, possible FecI RPA3282 77 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39936228 Common - possible polysaccharide deacetylase RPA3165 93 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 39934051 Common hypC putative hypC RPA0976 5 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 39936294 Common rplO 50S ribosomal protein L15 RPA3231 208 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 39934343 Common flbD two-component flagellar transcriptional activator FlbD, Fis-type RPA1268 172 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39935553 Common - possible DedA family. Putative integral membrane protein. RPA2487 75 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 39937703 Common cbbF fructose-1,6-bisphosphatase RPA4645 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 39934454 Common vnfK nitrogenase vanadium-iron protein, VnfK subunit RPA1380 48 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39934665 Common - hypothetical protein RPA1595 19 None None None 39933571 Common - sensor histidine kinase with PAS/PAC and Response regulator receiver domains RPA0494 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39935204 Common - sensor histidine kinase with a response regulator receiver domain RPA2135 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39935503 Common aroQ2 3-dehydroquinate dehydratase RPA2437 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 39933817 Common - possible Acyl-CoA dehydrogenase RPA0740 135 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39937889 Nonpathogen - hypothetical protein RPA4831 3 None None None 39937680 Nonpathogen - hypothetical protein RPA4622 5 None None None 39934206 Common - putative glycolate oxidase subunit GlcE RPA1131 152 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 39935236 Nonpathogen - hypothetical protein RPA2167 1 None None None 39937345 Common - hypothetical protein RPA4285 53 COG0778 NfnB, Nitroreductase Energy production and conversion 39937385 Common aroE putative shikimate 5-dehydrogenase RPA4325 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 39935606 Common hmgL 3-hydroxy-3-methylglutaryl-CoA lyase RPA2540 162 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 39934681 Common - putative dehydratase RPA1611 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39935239 Nonpathogen - hypothetical protein RPA2170 6 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 39937148 Common - probable membrane fusion protein (HlyD family of secretion proteins) linked to ABC efflux pumps RPA4088 123 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39935230 Common - possible transcriptional regulator, arsR family RPA2161 40 COG0640 ArsR, Predicted transcriptional regulators Transcription 39935849 Common dctP2 TrapT family, dctP subunit, C4-dicarboxylate periplasmic binding protein RPA2782 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 39933572 Common - hypothetical protein RPA0495 23 COG4246 COG4246, Uncharacterized protein conserved in bacteria Function unknown 39936609 Nonpathogen - hypothetical protein RPA3547 1 None None None 39937819 Nonpathogen - hypothetical protein RPA4761 1 None None None 39937647 Common - possible membrane protein involved in export of O-antigen RPA4589 20 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 39935765 Nonpathogen - hypothetical protein RPA2699 3 None None None 39936493 Common - possible hydrolase RPA3430 155 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39935031 Nonpathogen - hypothetical protein RPA1962 1 None None None 39933099 Common ccoN cytochrome-c oxidase fixN chain, heme and copper binding subunit RPA0019 136 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 39937411 Common - hypothetical protein RPA4351 59 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39936837 Common - possible RND efflux membrane fusion protein precursor RPA3776 177 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39934964 Common - possible peptidase RPA1895 16 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 39933400 Common - hypothetical protein RPA0323 147 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 39935868 Nonpathogen - Collagen triple helix repeat RPA2801 1 None None None 39934475 Common glnAIII putative glutamine synthetase III RPA1401 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 39934890 Nonpathogen - hypothetical protein RPA1821 3 None None None 39933288 Common - acetyl-CoA synthetase RPA0211 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 39934174 Common ruvC Holliday junction resolvase RPA1099 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 39936476 Common - Uncharacterized iron-regulated membrane protein DUF337 RPA3413 47 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 39934506 Common - putative nitroimidazole resistance protein RPA1432 55 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 39933189 Common - putative 3-oxoacyl-(acyl carrier ptn) reductase RPA0109 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936821 Common hpcC 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase RPA3760 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39937431 Common mutL DNA mismatch repair protein RPA4371 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 39934642 Common - putative carbon-monoxide dehydrogenase large subunit RPA1572 108 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 39935622 Common - PA-phosphatase related phosphoesterase RPA2556 14 None None None 39934511 Common anfD putative nitrogenase molybdenum-iron protein alpha chain (nitrogenase component I) (dinitrogenase) RPA1437 51 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39937078 Common - UDP-glucose-6-dehydrogenase RPA4018 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 39936752 Common - peptide ABC transporter, permease protein RPA3690 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 39934490 Common - putative branched-chain amino acid transport system ATP-binding protein RPA1416 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935643 Common - putative alginate o-acetyltransferase AlgI RPA2577 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 39935495 Common aat leucyl/phenylalanyl-tRNA--protein transferase RPA2429 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 39936156 Common - possible urea/short-chain binding protein of ABC transporter RPA3093 74 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934971 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg11 RPA1902 15 COG5281 COG5281, Phage-related minor tail protein Function unknown 39937034 Common - cytochrome c556 RPA3973 22 COG3909 COG3909, Cytochrome c556 Energy production and conversion 39933823 Common - possible deca-heme c-type cytochrome. RPA0746 26 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 39934808 Common - putative branched-chain amino acid transport system permease protein RPA1739 148 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934677 Common - Appr-1''-p processing enzyme family protein homolog RPA1607 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 39936444 Nonpathogen - Hpt domain RPA3381 4 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 39933864 Common - heat shock protein HtpX RPA0787 193 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 39935955 Common trpD anthranilate phosphoribosyltransferase RPA2890 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 39937523 Common - possible cytochrome RPA4463 27 COG3258 COG3258, Cytochrome c Energy production and conversion 39935253 Common - putative oxidoreductase RPA2184 186 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39937607 Nonpathogen - Phage integrase RPA4549 3 None None None 39937049 Common - putative phosphatase RPA3988 131 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 39934835 Common - acyl-CoA synthetase RPA1766 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39935444 Common - hypothetical protein RPA2374 5 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39934061 Common - possible urea/short-chain amide transport system permease protein RPA0986 138 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39935832 Common - enoyl-CoA hydratase RPA2765 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936757 Common - prephenate dehydratase RPA3695 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 39936867 Common livH permease of ABC transporter,putatively for branched chain amino acuds RPA3806 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39933190 Nonpathogen - probable transcriptional regulator, TetR family RPA0110 5 COG1309 AcrR, Transcriptional regulator Transcription 39937519 Common dhsU2 putative flavocytochrome C sulfide dehydrogenase, flavoprotein subunit RPA4459 52 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 39935468 Common - hypothetical protein RPA2401 11 COG4744 COG4744, Uncharacterized conserved protein Function unknown 39935676 Common ssuB aliphatic sulfonate transport ATP-binding protein, Subunit of ABC transporter RPA2610 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39937495 Common - hypothetical protein RPA4435 6 None None None 39937247 Common - two component sigma-54-dependent transcriptional regulator, Fis family RPA4187 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39936464 Nonpathogen - hypothetical protein RPA3401 1 None None None 39936638 Common thiE thiamin phosphate pyrophosphorylase RPA3576 197 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 39936625 Common - hypothetical protein RPA3563 6 None None None 39934728 Common ptpS putative 6-pyruvol tetrahydrobiopterin synthase RPA1658 127 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 39936648 Nonpathogen - hypothetical protein RPA3586 1 None None None 39937786 Common - hypothetical protein RPA4728 11 None None None 39934334 Common - putative cation-transporting P-type ATPase RPA1259 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 39936668 Nonpathogen - hypothetical protein RPA3606 1 None None None 39935108 Common - possible choline ABC transporter permease and substrate binding protein RPA2039 133 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 39936706 Common glgB glycogen branching enzyme RPA3644 145 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 39936314 Common rpsJ 30S ribosomal protein S10 RPA3251 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 39937108 Common rfbF alpha-D-glucose-1-phosphate cytidylyltransferase RPA4048 145 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 39937438 Common - maltose O-acetyltransferase RPA4378 206 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 39934291 Common - putative ABC transporter, permease protein RPA1216 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39934548 Common - putative periplasmic solute-binding protein RPA1476 76 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 39935284 Common - possible ATP-dependent exodeoxyribonuclease (subunit A) RPA2215 225 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 39937467 Common - permease protein of sugar ABC transporter RPA4407 154 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 39935793 Common ribD putative riboflavin-specific deaminase / reductase RPA2726 226 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 39935133 Common nosY putative NosY protein, possible ABC permease RPA2064 41 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 39936695 Common - hypothetical protein RPA3633 10 None None None 39935679 Common - putative aliphatic sulfonate binding protein, subunit of ABC transporter RPA2613 89 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39934011 Common - hypothetical protein RPA0934 55 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 39933782 Nonpathogen - hypothetical protein RPA0705 1 None None None 39934462 Common - hypothetical protein RPA1388 34 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 39933601 Common - putative geranyltranstransferase (farnesyl-diphosphate synthase) RPA0524 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 39934785 Nonpathogen - hypothetical protein RPA1715 5 None None None 39937880 Common - possible alcohol dehydrogenase RPA4822 170 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 39934825 Common - acetyl-CoA acetyltransferase RPA1756 20 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39934878 Nonpathogen - hypothetical protein RPA1809 2 None None None 39933351 Common glnK2 GlnK, nitrogen regulatory protein P-II RPA0274 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 39935631 Common - O-acetylserine (thiol) lyase C-terminal portion RPA2565 28 None None None 39937405 Nonpathogen - hypothetical protein RPA4345 3 None None None 39935341 Common - hypothetical protein RPA2272 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 39934897 Common - Pyrrolidone-carboxylate/pyroglutamyl peptidase I (C15) RPA1828 28 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 39934716 Nonpathogen - hypothetical protein RPA1646 3 None None None 39937236 Common rpsU 30S ribosomal protein S21 RPA4176 38 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 39937418 Common lgt prolipoprotein diacylglyceryl transferase RPA4358 205 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 39937480 Common - hypothetical protein RPA4420 38 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 39935629 Common aapP-1 amino acid ABC transporter, ATP-binding protein aapP-1 RPA2563 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 39934932 Nonpathogen - hypothetical protein RPA1863 2 None None None 39935089 Common - 3-oxoacyl-(acyl carrier protein) synthase II RPA2020 155 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39933161 Common coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase RPA0081 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 39933358 Common xthA1 possible exodeoxyribonuclease III RPA0281 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 39933180 Common oppC putative ABC transporter permease protein RPA0100 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39935017 Common pqqC pyrroloquinoline quinone biosynthesis protein PqqC RPA1948 36 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 39933298 Common matB malonyl-CoA synthase RPA0221 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934157 Common - hypothetical protein RPA1082 28 None None None 39936231 Common - hypothetical protein RPA3168 30 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 39933302 Common sodC putative superoxide dismutase (Cu/Zn) RPA0225 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 39937243 Nonpathogen - hypothetical protein RPA4183 5 None None None 39935069 Common leuA putative alpha-isopropylmalate/homocitrate synthase family transferase RPA2000 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 39936428 Nonpathogen - hypothetical protein RPA3365 3 None None None 39937826 Common - hypothetical protein RPA4768 11 None None None 39934523 Common - acyl-CoA synthetase RPA1449 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934713 Common - possible high affinity iron permease FTR1 RPA1643 36 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 39936641 Common - possible insertion element ISR1 hypothetical 10 KD protein A3 RPA3579 58 None None None 39935300 Common trbD conjugal transfer protein trbD RPA2231 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 39934316 Common - possible tonB transport protein RPA1241 43 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 39935562 Common - transcriptional regulator, GntR family RPA2496 133 COG1802 GntR, Transcriptional regulators Transcription 39936617 Common arsC3 arsenate reductase RPA3555 121 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 39934238 Common - possible epoxide hydrolase RPA1163 87 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39935372 Common - putative 3-hydroxyacyl-CoA dehydrogenase RPA2303 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935478 Common - putative permease of ABC transporter RPA2411 143 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39935919 Common argS arginyl-tRNA synthetase RPA2854 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39933428 Nonpathogen - hypothetical protein RPA0351 2 None None None 39934903 Common - hypothetical protein RPA1834 11 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 39937860 Common - hypothetical protein RPA4802 49 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 39936482 Common - possible transcriptional regulator, Crp/Fnr family RPA3419 29 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39936775 Common pimC pimeloyl-CoA dehydrogenase (large subunit) RPA3714 142 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39937114 Common - possible acetolactate synthase large subunit RPA4054 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39936899 Common - hypothetical protein RPA3838 66 COG1742 COG1742, Uncharacterized conserved protein Function unknown 39937022 Common - putative periplasmic binding protein for ABC transporter RPA3961 77 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 39934006 Nonpathogen - hypothetical protein RPA0929 2 None None None 39935101 Common ilvH acetolactate synthase 3 regulatory subunit RPA2032 190 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 39936127 Common - hypothetical protein RPA3064 96 None None None 39936103 Nonpathogen - hypothetical protein RPA3040 3 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 39935960 Common - possible small heat shock protein RPA2895 137 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 39936830 Common - probable transcriptional regulator, TetR family RPA3769 95 COG1309 AcrR, Transcriptional regulator Transcription 39934776 Common - putative enoyl-CoA hydratase RPA1706 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936114 Common purM phosphoribosylaminoimidazole synthetase RPA3051 230 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 39936421 Common - hypothetical protein RPA3358 16 COG3672 COG3672, Predicted periplasmic protein Function unknown 39933199 Common phyB3 Bacteriophytochrome (light-regulated signal transduction histidine kinase), PhyB3 RPA0122 217 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 39933696 Common ampG putative MFS transporter and signal transducer AmpG RPA0619 107 None None None 39935362 Nonpathogen - hypothetical protein RPA2293 2 None None None 39933393 Common - hypothetical protein RPA0316 65 COG3176 COG3176, Putative hemolysin General function prediction only 39937103 Common - possible ABC transporter, permease protein RPA4043 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39933761 Nonpathogen - hypothetical protein RPA0684 2 None None None 39936812 Common - hypothetical protein RPA3751 17 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 39936782 Common - possible ABC transporter, permease protein RPA3721 139 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39936142 Nonpathogen - hypothetical protein RPA3079 4 None None None 39934654 Common - hypothetical protein RPA1584 42 COG3106 COG3106, Predicted ATPase General function prediction only 39936092 Common - hypothetical protein RPA3029 10 None None None 39936655 Nonpathogen - Collagen triple helix repeat:Antifreeze protein, type I RPA3593 1 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 39936747 Common - leucine aminopeptidase RPA3685 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 39936713 Common - Ku domain RPA3651 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 39933880 Common - hypothetical protein RPA0803 90 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 39937181 Common trbE2 conjugal transfer protein trbE RPA4121 61 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 39933994 Common - probable transcriptional regulator, AraC family RPA0917 20 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 39937494 Common - MOSC domain RPA4434 32 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 39935638 Common - possible outer membrane efflux protein. RPA2572 132 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39934133 Common - probable transcriptional regulator, AraC family RPA1058 41 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39935174 Common - non-heme chloroperoxidase RPA2105 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39935965 Common - possible rifampin ADP-ribosyl transferase RPA2900 11 None None None 39933363 Common - putative diguanylate cyclase (GGDEF) with HAMP domain RPA0286 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39936459 Nonpathogen - hypothetical protein RPA3396 2 None None None 39933115 Common pheT phenylalanyl-tRNA synthetase subunit beta RPA0035 223 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 39936205 Common - hypothetical protein RPA3142 7 None None None 39934154 Common - probable 4-methylmuconolactone Major Facilitator Family (MFS) transporter RPA1079 174 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39934844 Common - putative dehydrogenase RPA1775 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39933134 Common - putative small heat shock protein RPA0054 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 39935881 Common ssb single-strand DNA-binding protein RPA2814 207 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 39936409 Common - possible mannosyltransferase RPA3346 157 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39937751 Common - putative FMN oxidoreductase RPA4693 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 39934550 Common - putative permease protein RPA1478 181 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 39936184 Common - putative alginate o-acetyltransferase AlgI RPA3121 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 39936554 Common dyr dihydrofolate reductase RPA3492 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 39937540 Common czcB possible RND divalent metal cation efflux membrane fusion protein CzcB precursor RPA4480 116 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39934753 Common - 3-oxoacyl-acyl carrier protein reductase RPA1683 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936437 Common ppnK inorganic polyphosphate/ATP-NAD kinase RPA3374 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 39935168 Common - Putative diterpenoid Major Facilitator Superfamily (MFS) transporter RPA2099 106 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936019 Common pepT peptidase T RPA2954 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 39933617 Common - hypothetical protein RPA0540 13 None None None 39935879 Common - probable HlyC/CorC family of transporters with 2 CBS domains RPA2812 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 39937057 Common - probable transcriptional regulator, Crp/Fnr family RPA3996 167 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39934930 Nonpathogen - hypothetical protein RPA1861 4 None None None 39937840 Common - hypothetical protein RPA4782 56 COG0392 COG0392, Predicted integral membrane protein Function unknown 39934995 Common - possible transcriptional regulator, XRE family RPA1926 41 None None None 39936372 Common - hypothetical protein RPA3309 30 COG3652 COG3652, Predicted outer membrane protein Function unknown 39935532 Common sufD sufD, needed for fhuF Fe-S center production/stability RPA2466 169 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 39937758 Common ligI 2-pyrone-4,6-dicarboxylic acid hydrolase RPA4700 42 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 39934499 Common cysE1 serine acetyltransferase RPA1425 194 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 39934958 Nonpathogen - hypothetical protein RPA1889 4 None None None 39934875 Common - L-carnitine dehydratase/bile acid-inducible protein F RPA1806 111 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39935791 Common glyA serine hydroxymethyltransferase RPA2724 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 39937453 Nonpathogen - hypothetical protein RPA4393 3 None None None 39935373 Common - putative acyl-CoA thiolase RPA2304 178 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39934634 Common - possible urea/short-chain amide transport system substrate-binding protein RPA1564 90 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39933846 Nonpathogen - hypothetical protein RPA0769 2 None None None 39936805 Nonpathogen - hypothetical protein RPA3744 3 None None None 39934288 Common - hypothetical protein RPA1213 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 39936077 Nonpathogen pucBd light harvesting protein B-800-850, beta chain D (antenna pigment protein, beta chain D) (LH II-D beta) RPA3013 7 None None None 39934031 Common - possible histone deacetylase or acetylpolyamine aminohydrolase or acetoin utilization protein RPA0954 159 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 39935853 Nonpathogen - hypothetical protein RPA2786 5 None None None 39934149 Nonpathogen - hypothetical protein RPA1074 6 None None None 39933167 Common - putative Major Facilitator Superfamily (MFS) transporter RPA0087 102 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936380 Nonpathogen - hypothetical protein RPA3317 1 None None None 39934435 Nonpathogen - hypothetical protein RPA1361 1 None None None 39934585 Common crtB CrtB phytoene synthase RPA1513 109 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 39937473 Common - possible transcriptional regulator, TetR family RPA4413 45 COG1309 AcrR, Transcriptional regulator Transcription 39933646 Common - hypothetical protein RPA0569 9 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 39934983 Common - possible glycohydrolase RPA1914 24 COG3179 COG3179, Predicted chitinase General function prediction only 39937663 Common fixA electron trnasfer flavoprotein beta chain fixA RPA4605 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 39937833 Common phoB two-component phosphate transcriptional regulator PhoB RPA4775 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39934612 Common bchN light-independent protochlorophyllide reductase subunit N RPA1542 30 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39936915 Nonpathogen - hypothetical protein RPA3854 1 None None None 39936749 Common - putative MutT/ADP-ribose pyrophosphatase RPA3687 116 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 39933543 Nonpathogen - hypothetical protein RPA0466 7 None None None 39934425 Common exbD2 transport protein ExbD RPA1351 140 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 39936944 Common flhB flagellar biosynthesis protein FlhB RPA3883 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 39933851 Common - hypothetical protein RPA0774 43 COG3304 COG3304, Predicted membrane protein Function unknown 39935819 Common - possible succinoglycan biosynthesis transport protein exoP RPA2752 75 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 39935164 Common - possible cobalamin (5`-phosphate) synthase RPA2095 137 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 39936053 Common yrkN GCN5-related N-acetyltransferase RPA2988 7 None None None 39937668 Common - Protein of unknown function, HesB/YadR/YfhF RPA4610 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 39935641 Common - possible RND efflux transporter RPA2575 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39937717 Common - possible acetyltransferase RPA4659 26 COG3153 COG3153, Predicted acetyltransferase General function prediction only 39935273 Common - integrase RPA2204 115 COG0582 XerC, Integrase DNA replication, recombination, and repair 39937335 Nonpathogen - hypothetical protein RPA4275 1 None None None 39934200 Common - YaeN protein RPA1125 195 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 39934820 Common - putative branched-chain amino acid transport system ATP-binding protein RPA1751 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935413 Common - hypothetical protein RPA2344 8 None None None 39933763 Common - hypothetical protein RPA0686 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 39937534 Common - transcriptional regulator, ArsR family RPA4474 117 COG0640 ArsR, Predicted transcriptional regulators Transcription 39933870 Common - hypothetical protein RPA0793 14 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 39934219 Nonpathogen - hypothetical protein RPA1144 9 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39936260 Nonpathogen - hypothetical protein RPA3197 2 None None None 39937188 Common - hypothetical protein RPA4128 14 None None None 39935224 Common ilvD3 dihydroxy-acid dehydratase RPA2155 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 39937605 Nonpathogen - hypothetical protein RPA4547 1 None None None 39937739 Common - possible asmA protein RPA4681 54 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 39936087 Nonpathogen - hypothetical protein RPA3024 2 None None None 39934298 Nonpathogen - hypothetical protein RPA1223 1 None None None 39934829 Common - hypothetical protein RPA1760 10 None None None 39937043 Common - Glycosyl transferase, family 4 RPA3982 13 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 39935616 Nonpathogen - hypothetical protein RPA2550 1 None None None 39934140 Common - Metal dependent phosphohydrolase RPA1065 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 39936889 Common - transcriptional regulator, XRE family RPA3828 18 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 39936551 Common - hypothetical protein RPA3489 13 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 39933877 Common matE1 putative cation efflux pump, DNA-damage-inducible protein RPA0800 90 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 39935339 Nonpathogen - hypothetical protein RPA2270 1 None None None 39934242 Common yfcB N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase RPA1167 225 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 39936674 Nonpathogen - hypothetical protein RPA3612 1 None None None 39933997 Common - GCN5-related N-acetyltransferase RPA0920 52 COG0456 RimI, Acetyltransferases General function prediction only 39934852 Nonpathogen - possible TrapT family, dctQ subunit, C4-dicarboxylate transport RPA1783 6 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 39937618 Common - transcriptional regulator, IclR family RPA4560 106 COG1414 IclR, Transcriptional regulator Transcription 39933940 Common - possible MgtC-magnesium transport RPA0863 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 39933187 Common - putative Zn-binding dehydrogenase RPA0107 159 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 39933770 Common phnI PhnI protein, phosphonate metabolism, function unknown RPA0693 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 39936872 Common - Excinuclease ABC, C subunit, N-terminal RPA3811 42 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 39934653 Common - hypothetical protein RPA1583 44 COG3768 COG3768, Predicted membrane protein Function unknown 39936928 Common - hypothetical protein RPA3867 14 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 39933153 Common trxA thioredoxin RPA0073 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 39937847 Common - sensor histidine kinase RPA4789 216 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39933255 Common atpA F0F1 ATP synthase subunit alpha RPA0178 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 39935092 Nonpathogen - hypothetical protein RPA2023 3 None None None 39933228 Common - possible iron ABC transporter periplasmic binding protein RPA0151 102 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 39936316 Common fusA elongation factor G RPA3253 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 39937116 Nonpathogen - hypothetical protein RPA4056 2 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 39933960 Common - ABC transporter, ATP-binding protein RPA0883 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39936839 Common - putative cytochrome p450-like enzyme RPA3778 90 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 39934863 Common - transcriptional regulator, MarR family RPA1794 75 COG1846 MarR, Transcriptional regulators Transcription 39933949 Common - putative peptidyl-dipeptidase RPA0872 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 39935070 Common - hypothetical protein RPA2001 121 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39937225 Common - hypothetical protein RPA4165 76 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 39936718 Common - hypothetical protein RPA3656 82 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 39934774 Common - probable transcriptional regulator, TetR family RPA1704 27 COG1309 AcrR, Transcriptional regulator Transcription 39934546 Nonpathogen - hypothetical protein RPA1474 1 None None None 39935716 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA2650 75 COG2510 COG2510, Predicted membrane protein Function unknown 39933552 Common - putative oxidoreductase RPA0475 141 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 39935886 Common - hypothetical protein RPA2819 10 COG4634 COG4634, Uncharacterized protein conserved in bacteria Function unknown 39936063 Common dapA1 putative dihydrodipicolinate synthase RPA2998 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 39936961 Common flgG flagellar basal body rod protein FlgG RPA3900 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 39934703 Common fliI flagellum-specific ATP synthase RPA1633 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 39935150 Common - possible Fe ABC Transporter RPA2081 63 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 39933178 Common oppF oligopeptide ABC transporter (ATP-binding protein) RPA0098 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 39937002 Nonpathogen - hypothetical protein RPA3941 4 None None None 39937622 Common - Phenylacetic acid degradation-related protein:Thioesterase superfamily RPA4564 46 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39936072 Nonpathogen - hypothetical protein RPA3007 1 None None None 39937675 Common nifE nitrogenase molybdenum-cofactor synthesis protein nifE RPA4617 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39937429 Common - transcriptional regulator, MarR family RPA4369 47 COG1846 MarR, Transcriptional regulators Transcription 39936627 Common - ErfK/YbiS/YcfS/YnhG RPA3565 85 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39933271 Common - 2'_5' RNA ligase RPA0194 117 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 39936766 Common - Excinuclease ABC, C subunit, N-terminal RPA3704 42 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 39935931 Common - pyruvate dehydrogenase subunit beta RPA2866 216 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 39933963 Common - putative diguanylate cyclase (GGDEF) RPA0886 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39937766 Common - hypothetical protein RPA4708 86 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 39937137 Common - ATPase, ParA type RPA4077 113 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 39933137 Common ugpA sn-glycerol-3-phosphate transport system permease protein RPA0057 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 39934926 Nonpathogen - hypothetical protein RPA1857 8 None None None 39933813 Common fdsD possible NAD-dependent formate dehydrogenase delta subunit RPA0736 26 None None None 39937863 Nonpathogen - hypothetical protein RPA4805 1 None None None 39936884 Nonpathogen - hypothetical protein RPA3823 2 None None None 39933342 Common algJ possible AlgJ protein, required for O-acetylation of alginate in Pseudomonas aeruginosa. RPA0265 3 COG5038 COG5038, Ca2+-dependent lipid-binding protein, contains C2 domain General function prediction only 39933562 Common - possible urea/short-chain amide ABC transporter RPA0485 57 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935664 Common - GTP binding protein-like RPA2598 222 COG2262 HflX, GTPases General function prediction only 39935418 Common metY putative homocysteine synthase RPA2349 203 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 39933587 Common secA preprotein translocase subunit SecA RPA0510 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 39933305 Nonpathogen - hypothetical protein RPA0228 4 None None None 39933972 Common - putative 3-oxoacyl-[ACP] reductase RPA0895 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936503 Common - amidase RPA3440 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39935432 Common NifD1 possible nitrogenase molybdenum-iron protein alpha chain (nitrogenase component I) (dinitrogenase) RPA2363 59 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39936376 Nonpathogen - hypothetical protein RPA3313 3 None None None 39936532 Common - putative sugar uptake ABC transporter periplasmic solute-binding protein precursor RPA3470 38 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 39937303 Common phaC putative poly-beta-hydroxyalkanoate synthase RPA4243 77 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 39936412 Common - putative exopolysaccharide biosynthesis protein RPA3349 34 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 39936234 Common - hypothetical protein RPA3171 15 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 39937265 Common - possible polysaccharide export protein, PST family RPA4205 30 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 39933470 Common - PA-phosphatase related phosphoesterase RPA0393 17 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 39936258 Common - indolepyruvate ferredoxin oxidoreductase RPA3195 89 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 39933673 Nonpathogen - hypothetical protein RPA0596 2 None None None 39936282 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) RPA3219 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39936791 Common - GMC-type oxidoreductase RPA3730 89 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 39935901 Common - hypothetical protein RPA2834 19 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39933490 Common - putative methylenetetrahydrofolate dehydrogenase RPA0413 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 39933518 Common - hypothetical protein RPA0441 18 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 39933787 Nonpathogen - hypothetical protein RPA0710 1 None None None 39933349 Common glnK1 GlnK, nitrogen regulatory protein P-II RPA0272 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 39933260 Common - hypothetical protein RPA0183 15 None None None 39936276 Nonpathogen - hypothetical protein RPA3213 1 None None None 39935398 Common - putative ABC transporter permease protein RPA2329 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39935913 Common tatB possible sec-independent protein secretion pathway component TatB RPA2848 51 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 39937125 Nonpathogen - hypothetical protein RPA4065 1 None None None 39937351 Nonpathogen pucBb light harvesting protein B-800-850, beta chain B (antenna pigment protein, beta chain B) RPA4291 7 None None None 39933477 Common - possible alcohol dehydrogenase and quinone oxidoreductase RPA0400 182 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39934854 Common - hypothetical protein RPA1785 16 None None None 39936164 Common - hypothetical protein RPA3101 15 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 39936991 Nonpathogen - hypothetical protein RPA3930 8 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 39934120 Common glyQ glycyl-tRNA synthetase subunit alpha RPA1045 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 39937080 Common - possible branched-chain amino acid transport system permease protein RPA4020 131 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39937510 Nonpathogen - hypothetical protein RPA4450 8 None None None 39934198 Common - omp16 protein RPA1123 152 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 39934977 Nonpathogen - hypothetical protein RPA1908 1 None None None 39934136 Common tcmP possible polyketide synthesis protein RPA1061 32 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 39935452 Common - putative iron(III) ABC transporter, permease protein RPA2383 56 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 39936149 Nonpathogen - hypothetical protein RPA3086 1 None None None 39936540 Common exbB5 possible exbB, uptake of enterochelin; tonB-dependent uptake of B colicins RPA3478 151 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39935063 Common - hypothetical protein RPA1994 15 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 39937296 Common - hypothetical protein RPA4236 58 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 39936574 Common - hypothetical protein RPA3512 19 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 39934112 Common - possible electron transfer flavoprotein dehydrogenase RPA1037 107 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 39936123 Common - leucyl aminopeptidase RPA3060 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 39936208 Common - possible transglycosylase SLT domain RPA3145 40 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 39934358 Common - homoserine/homoserine lactone/threonine efflux protein RPA1283 104 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 39933599 Common - possible activator of photopigment and puc with BLUF domain RPA0522 35 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 39937279 Common - hypothetical protein RPA4219 10 None None None 39933157 Nonpathogen - hypothetical protein RPA0077 3 None None None 39933623 Nonpathogen - hypothetical protein RPA0546 1 None None None 39934592 Common crtF hydroxyneurosporene methyltransferase CrtF RPA1520 48 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39933593 Common - transcriptional regulator, MarR family RPA0516 45 COG1846 MarR, Transcriptional regulators Transcription 39935260 Common - hypothetical protein RPA2191 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 39933144 Common rpsA 30S ribosomal protein S1 RPA0064 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 39933149 Common trpB tryptophan synthase subunit beta RPA0069 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 39937653 Common - hypothetical protein RPA4595 160 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39935659 Common ntrC nitrogen assimilation regulatory protein ntrC Response regulator RPA2593 217 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39934352 Common - possible beta-ketoadipate enol-lactone hydrolase RPA1277 116 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39936549 Common - hypothetical protein RPA3487 49 None None None 39934277 Common - putative Adenylate/Guanylate cyclase RPA1202 73 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 39934667 Common purQ phosphoribosylformylglycinamidine synthase II RPA1597 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 39934966 Nonpathogen GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg7 RPA1897 4 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 39934761 Common matE3 probable cation efflux pump (multidrug resistance protein) RPA1691 83 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 39933986 Common wrbA TrpR binding protein WrbA RPA0909 116 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 39933193 Common - putative oxidoreductase RPA0113 121 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 39935993 Common proS prolyl-tRNA synthetase RPA2928 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39935426 Common - cystathionine gamma-lyase RPA2357 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 39935573 Common - possible haloacid dehalogenase RPA2507 45 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 39933869 Nonpathogen - hypothetical protein RPA0792 3 None None None 39933848 Common - possible protein commonly found in insertion elements RPA0771 58 None None None 39937122 Common - hypothetical protein RPA4062 4 None None None 39934129 Common nadB L-aspartate oxidase RPA1054 225 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 39935005 Common - possible serine protease/outer membrane autotransporter RPA1936 147 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 39934515 Nonpathogen - possible uridylate kinase RPA1441 17 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 39935771 Nonpathogen - hypothetical protein RPA2705 1 None None None 39934597 Nonpathogen pufB light-harvesting complex 1 beta chain RPA1525 9 None None None 39933094 Common rdxH hypothetical protein RPA0014 22 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 39935590 Common - Sir2 family, possible ADP ribosyltransferase RPA2524 151 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 39936521 Common - possible TrapT family, fused dctM-Q subunits, C4-dicarboxylate transport RPA3459 77 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 39934410 Common - hypothetical protein RPA1336 49 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 39934619 Nonpathogen - possible photosynthetic complex assembly protein RPA1549 9 None None None 39935595 Nonpathogen - hypothetical protein RPA2529 1 None None None 39937682 Common - hypothetical protein RPA4624 8 None None None 39933634 Common cysK cysteine synthase, cytosolic O-acetylserine(thiol)lyase RPA0557 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 39934102 Common - hypothetical protein RPA1027 85 COG2321 COG2321, Predicted metalloprotease General function prediction only 39934258 Common - hypothetical protein RPA1183 31 None None None 39936620 Common - possible permease RPA3558 60 COG0701 COG0701, Predicted permeases General function prediction only 39933536 Common - possible fatty acid-CoA ligase RPA0459 71 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934223 Common - putative sugar transferase RPA1148 185 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39935986 Common tsf elongation factor Ts RPA2921 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 39936394 Nonpathogen - hypothetical protein RPA3331 1 None None None 39937175 Common trbI2 putative conjugal transfer protein trbI RPA4115 57 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 39933703 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase RPA0626 139 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 39933908 Common coxB cytochrome c oxidase subunit II RPA0831 140 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 39936612 Common - Coenzyme B12-binding:Elongator protein 3/MiaB/NifB RPA3550 79 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 39934022 Common cbbT2 transketolase RPA0945 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 39934397 Common - possible FusB/FusC fusaric acid resistance pump RPA1324 31 COG1289 COG1289, Predicted membrane protein Function unknown 39933735 Common badE benzoyl-CoA reductase subunit RPA0658 18 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 39935588 Nonpathogen - hypothetical protein RPA2522 3 None None None 39935077 Common - hypothetical protein RPA2008 8 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 39937063 Common - putative acyl-CoA dehydrogenase RPA4002 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39937330 Common thrB homoserine kinase RPA4270 65 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 39936398 Nonpathogen - hypothetical protein RPA3335 1 None None None 39937433 Common - possible protease RPA4373 177 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 39937603 Nonpathogen - hypothetical protein RPA4545 1 None None None 39937208 Common prsA phosphoribosylpyrophosphate synthetase RPA4148 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 39933717 Common fliC putative flagellin RPA0640 126 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 39935725 Common glmU UDP-N-acetylglucosamine pyrophosphorylase RPA2659 237 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 39937313 Common nuoM2 NADH-ubiquinone dehydrogenase chain M RPA4253 206 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 39937395 Common - replicative DNA helicase RPA4335 176 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 39934286 Nonpathogen - hypothetical protein RPA1211 2 None None None 39936518 Common - possible methylmalonyl-CoA decarboxylase alpha chain RPA3455 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 39934096 Common - putative transporter, AcrB/D/F family; Cation efflux system protein RPA1021 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39934325 Common - amide-urea binding protein RPA1250 129 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39936501 Nonpathogen - hypothetical protein RPA3438 1 None None None 39933088 Common kaiB circadian clock protein RPA0008 25 None None None 39937369 Common serC phosphoserine aminotransferase RPA4309 64 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 39936905 Common kefB possible glutathione-regulated potassium-efflux system protein kefB RPA3844 175 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 39935925 Common - hypothetical protein RPA2860 4 None None None 39933233 Common - tonB like protein RPA0156 15 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 39937730 Common hmgA homogentisate 1,2-dioxygenase RPA4672 51 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 39937741 Nonpathogen - hypothetical protein RPA4683 3 None None None 39936343 Common hasR possible heme receptor RPA3280 77 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39933892 Common - hypothetical protein RPA0815 21 None None None 39936513 Common - putative malonic semialdehyde oxidative decarboxylase RPA3450 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39933267 Common sucD succinyl-CoA synthetase alpha-subunit RPA0190 209 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 39937166 Common rmrB putative multidrug efflux pump, Major Facilitator Superfamily (MFS) RPA4106 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39933580 Common aroB putative 3-dehydroquinate synthase RPA0503 213 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 39937584 Nonpathogen - hypothetical protein RPA4526 1 None None None 39934779 Common - putative acyl-CoA dehydrogenase RPA1709 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934919 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA1850 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39936241 Common - hypothetical protein RPA3178 28 COG4852 COG4852, Predicted membrane protein Function unknown 39936579 Common dnlJ DNA ligase RPA3517 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 39936046 Common - P2 ISBm2 RPA2981 53 None None None 39934185 Common - putative 3-oxoacyl-acyl carrier protein reductase RPA1110 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934443 Common - hypothetical protein RPA1369 111 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 39935028 Common - putative RND efflux membrane protein RPA1959 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39937089 Common - possible branched-chain amino acid ABC transport system substrate-binding protein RPA4029 139 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934047 Common hupK putative hydrogenase expression/formation protein hupK RPA0972 30 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 39937854 Common - ErfK/YbiS/YcfS/YnhG RPA4796 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39933320 Common rimM putative 16S rRNA processing protein. RPA0243 181 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 39936012 Common nuoE1 NADH dehydrogenase subunit E RPA2947 154 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 39933162 Common ubiB ubiquinone biosynthesis protein AarF, a gene required for the first monooxygenase step in CoQ biosynthesis, recently renamed ubiB RPA0082 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 39935528 Common - hypothetical protein RPA2462 84 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 39935318 Common - putative methylase/helicase RPA2249 21 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 39934911 Common - hypothetical protein RPA1842 8 None None None 39936028 Nonpathogen - hypothetical protein RPA2963 1 COG1846 MarR, Transcriptional regulators Transcription 39935705 Common - probable L-2-amino-thiazoline-4-carboxylic acid hydrolase RPA2639 8 None None None 39934209 Nonpathogen - hypothetical protein RPA1134 19 None None None 39936005 Common nuoK1 NADH dehydrogenase subunit K RPA2940 84 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 39936173 Nonpathogen - hypothetical protein RPA3110 3 None None None 39935944 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase RPA2879 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 39937028 Common - putative threonine dehydratase RPA3967 194 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 39935785 Nonpathogen - hypothetical protein RPA2718 3 None None None 39936952 Nonpathogen - hypothetical protein RPA3891 10 COG5373 COG5373, Predicted membrane protein Function unknown 39936586 Common ftsQ putative cell division protein FtsQ RPA3524 66 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 39935021 Common - hypothetical protein RPA1952 13 None None None 39935783 Nonpathogen - hypothetical protein RPA2716 2 None None None 39934212 Nonpathogen - hypothetical protein RPA1137 3 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 39934735 Nonpathogen - hypothetical protein RPA1665 1 None None None 39934014 Common - extragenic suppressor protein SuhB; Inositol monophosphatase family RPA0937 212 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 39936242 Common - Deoxyribodipyrimidine photolyase RPA3179 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 39933990 Common - hypothetical protein RPA0913 130 COG1678 COG1678, Putative transcriptional regulator Transcription 39935627 Common aapQ-1 polar amino acid ABC transport permease protein aapQ-1 RPA2561 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 39933762 Common - transcriptional regulator, IclR family RPA0685 90 COG1414 IclR, Transcriptional regulator Transcription 39935178 Common - two-component transcriptional regulator, LuxR family RPA2109 215 COG4566 TtrR, Response regulator Signal transduction mechanisms 39934707 Nonpathogen - hypothetical protein RPA1637 3 None None None 39935027 Common - transcriptional regulator, TetR family RPA1958 135 COG1309 AcrR, Transcriptional regulator Transcription 39935176 Common - sensor histidine kinase with a GAF, a Ser/Thr protein kinase, and an unknown domain RPA2107 216 COG3899 COG3899, Predicted ATPase General function prediction only 39937304 Common - hypothetical protein RPA4244 35 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39933457 Common - possible oxidoreductase similar to formate dehydrogenase and cbbBc of R. eutropha. RPA0380 170 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 39937032 Common thiD phosphomethylpyrimidine kinase (hmp-phosphate kinase) RPA3971 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 39934918 Nonpathogen - hypothetical protein RPA1849 1 None None None 39936048 Nonpathogen - hypothetical protein RPA2983 1 None None None 39934794 Common paaI putative phenylacetic acid degredation protein RPA1724 66 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39937425 Common - GCN5-related N-acetyltransferase RPA4365 30 COG0456 RimI, Acetyltransferases General function prediction only 39937834 Common phoU phosphate regulon transcriptional regulator, phoU RPA4776 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 39934660 Nonpathogen - hypothetical protein RPA1590 5 None None None 39933103 Common gstA3 possible glutathione transferase RPA0023 89 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39937011 Common - possible glycosyl transferase RPA3950 77 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39937592 Nonpathogen - hypothetical protein RPA4534 3 None None None 39936561 Common - hypothetical protein RPA3499 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 39937574 Common vieA putative cylclic diguanylate phosphodiesterase (EAL) RPA4516 159 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 39933955 Common - transcriptional regulator, AraC type; possible DNA gyrase inhibitor RPA0878 126 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 39934099 Common - putative oxidoreductase RPA1024 48 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 39935946 Common - hypothetical protein RPA2881 14 None None None 39936887 Common - hypothetical protein RPA3826 41 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 39933277 Common - hypothetical protein RPA0200 30 None None None 39935769 Common parC DNA topoisomerase IV subunit A RPA2703 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 39935782 Common - possible transcriptional regulator, MarR family RPA2715 22 COG1846 MarR, Transcriptional regulators Transcription 39936512 Nonpathogen - PilT protein, N-terminal RPA3449 6 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 39936934 Nonpathogen - hypothetical protein RPA3873 5 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 39937611 Common - putative acyl-CoA dehydrogenase RPA4553 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39937219 Common potH polyamine ABC transporter permease protein RPA4159 182 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 39935635 Common cfa1 cyclopropane-fatty-acyl-phospholipid synthase RPA2569 128 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 39936060 Common nuoL3 possible NADH-Ubiquinone/plastoquinone (complex I) RPA2995 202 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 39937316 Common nuoJ2 NADH-ubiquinone dehydrogenase chain J RPA4256 46 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 39933582 Nonpathogen - hypothetical protein RPA0505 3 None None None 39937298 Common - putative permease of ABC transporter RPA4238 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 39933147 Nonpathogen - hypothetical protein RPA0067 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 39933663 Common - putative PAN2 protein ; short shain alcohol dehydrogenase RPA0586 229 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39937068 Nonpathogen - hypothetical protein RPA4008 1 None None None 39934354 Nonpathogen - hypothetical protein RPA1279 1 None None None 39936361 Common - hypothetical protein RPA3298 14 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 39933301 Common - similar to eukaryotic molybdopterin oxidoreductase:Tat pathway signal RPA0224 130 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 39935011 Common - putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase RPA1942 177 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 39936502 Common - putative hydrolase RPA3439 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 39936611 Common - possible hydrolase RPA3549 51 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 39933677 Common - hypothetical protein RPA0600 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 39936355 Nonpathogen - hypothetical protein RPA3292 1 None None None 39933441 Common - possible permease RPA0364 79 COG0730 COG0730, Predicted permeases General function prediction only 39934841 Common ppc phosphoenolpyruvate carboxylase RPA1772 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 39935731 Common - possible acid-CoA ligase RPA2665 52 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39937112 Common - possible 3-dehydroquinate synthase RPA4052 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 39934778 Common - putative acyl-CoA dehydrogenase RPA1708 142 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39936179 Common ipdC indole-3-pyruvate decarboxylase RPA3116 221 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 39934700 Common cheB2 chemotaxis-specific methylesterase RPA1630 206 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 39934039 Common hupC Ni/Fe-hydrogenase 1 B-type cytochrome subunit RPA0964 45 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 39935964 Common - hypothetical protein RPA2899 21 COG0824 FcbC, Predicted thioesterase General function prediction only 39936120 Common - ABC transporter, duplicated ATPase domains RPA3057 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 39937363 Common - hypothetical protein RPA4303 25 COG1633 COG1633, Uncharacterized conserved protein Function unknown 39934360 Common - hypothetical protein RPA1285 12 COG2105 COG2105, Uncharacterized conserved protein Function unknown 39933951 Common - hypothetical protein RPA0874 39 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 39933460 Common - enoyl-CoA hydratase RPA0383 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936553 Common hflK putative protease subunit hflK RPA3491 178 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 39936584 Common ftsZ cell division protein FtsZ RPA3522 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 39935042 Common - 3-hydroxyisobutyrate dehydrogenase RPA1973 186 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 39937874 Common - two component sensor histidine kinase RPA4816 162 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39933086 Common - transcriptional regulator, AsnC family RPA0006 152 COG1522 Lrp, Transcriptional regulators Transcription 39936000 Common - Beta-lactamase-like RPA2935 150 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 39937142 Common - possible phage-like integrase RPA4082 80 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 39933254 Common atpG F0F1 ATP synthase subunit gamma RPA0177 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 39935347 Common - possible ABC transporter, permease protein RPA2278 153 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934556 Common pgm2 phosphoglucomutase RPA1484 235 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 39934248 Common cspA1 cold shock DNA binding protein RPA1173 181 COG1278 CspC, Cold shock proteins Transcription 39937511 Nonpathogen - hypothetical protein RPA4451 8 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 39933670 Nonpathogen - hypothetical protein RPA0593 1 None None None 39937012 Common gmd GDP-mannose 4,6-dehydratase RPA3951 220 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 39934516 Common - possible uridine monophosphate kinase RPA1442 40 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 39934736 Common hemN1 coproporphyrinogen III oxidase RPA1666 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 39933898 Common - transcriptional regulator, MarR family RPA0821 54 COG1846 MarR, Transcriptional regulators Transcription 39935316 Common - hypothetical protein RPA2247 21 None None None 39935778 Common - hypothetical protein RPA2711 15 COG1714 COG1714, Predicted membrane protein/domain Function unknown 39933820 Common - putative acid-CoA ligase RPA0743 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39937133 Common - DoxD-like family RPA4073 25 COG2259 COG2259, Predicted membrane protein Function unknown 39934743 Common - putative phosphoketolase RPA1673 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 39933710 Common rnpA probable ribonuclease p protein component (protein c5) RPA0633 32 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 39934027 Common tly putative hemolysin RPA0950 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 39934599 Common pufL photosynthetic reaction center L subunit RPA1527 21 None None None 39935883 Common uvrA excinuclease ABC subunit A RPA2816 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 39935061 Common - possible NtrR protein RPA1992 45 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 39935724 Nonpathogen - hypothetical protein RPA2658 3 None None None 39936247 Common - putative cylclic diguanylate phosphodiesterase (EAL) RPA3184 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 39937331 Common lytB2 penicillin tolerance protein (lytB) , control of stringent response RPA4271 186 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 39933109 Common - hypothetical protein RPA0029 44 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 39935840 Common - epoxide hydrolase RPA2773 140 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39937163 Common - possible glutathione S-transferase RPA4103 90 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39934090 Common - transcriptional regulator, PadR family RPA1015 68 COG1695 COG1695, Predicted transcriptional regulators Transcription 39936370 Common xthA3 putative exonuclease III RPA3307 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 39935016 Common pqqB pyrroloquinoline quinone biosynthesis protein PqqB RPA1947 36 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 39936618 Common arsR2 transcriptional regulator, ArsR family, ArsR2 RPA3556 63 COG4189 COG4189, Predicted transcriptional regulator Transcription 39934251 Common - hypothetical protein RPA1176 30 COG5496 COG5496, Predicted thioesterase General function prediction only 39935422 Common nifH1 putative nitrogenase NifH subunit RPA2353 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39934547 Nonpathogen - hypothetical protein RPA1475 1 None None None 39934271 Common pdxH pyridoxamine 5'-phosphate oxidase RPA1196 133 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 39937191 Common - Helix-turn-helix protein, CopG family RPA4131 23 None None None 39933925 Common - hypothetical protein RPA0848 50 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 39933507 Common oxyR hydrogen peroxide-inducible transcriptional regulator OxyR, LysR family RPA0430 182 COG0583 LysR, Transcriptional regulator Transcription 39933405 Common - putative deoxyribonucleotide triphosphate pyrophosphatase RPA0328 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 39934260 Common - putative methanol dehydrogenase regulator RPA1185 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 39936900 Common pchR putative transcriptional regulator PchR, AraC family RPA3839 54 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39935762 Common lepB2 putative signal peptidase I RPA2696 207 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 39934680 Common - hypothetical protein RPA1610 33 COG3777 COG3777, Uncharacterized conserved protein Function unknown 39934866 Common - hypothetical protein RPA1797 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 39935866 Common pdxK putative pyridoxamine kinase RPA2799 120 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 39933748 Common hbaC 4-hydroxybenzoyl-CoA reductase,second of three subunits RPA0671 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 39935356 Common - hypothetical protein RPA2287 3 COG1787 COG1787, Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes Defense mechanisms 39934768 Common - DUF81 RPA1698 31 COG0730 COG0730, Predicted permeases General function prediction only 39936909 Common gcvT2 glycine cleavage system protein T2 RPA3848 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 39937588 Common - hypothetical protein RPA4530 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 39937003 Nonpathogen - hypothetical protein RPA3942 3 None None None 39935792 Common - hypothetical protein RPA2725 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 39937731 Common cphA1 putative beta lactamase precursor RPA4673 77 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39933686 Common - hypothetical protein RPA0609 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39933780 Common - hypothetical protein RPA0703 27 None None None 39933732 Common badR Benzoate anaerobic degradation transcriptional regulator BadR, MarR family RPA0655 52 COG1846 MarR, Transcriptional regulators Transcription 39933316 Nonpathogen - hypothetical protein RPA0239 1 COG4371 COG4371, Predicted membrane protein Function unknown 39933311 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA0234 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39934071 Common - Alpha/beta hydrolase fold RPA0996 178 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39935477 Common - putative urea/short-chain amide transport system substrate-binding protein RPA2410 116 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935620 Common - penicillin binding protein RPA2554 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 39936865 Common - hypothetical protein RPA3804 41 COG3427 COG3427, Uncharacterized conserved protein Function unknown 39933365 Common - hypothetical protein RPA0288 15 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 39937553 Nonpathogen - hypothetical protein RPA4493 3 None None None 39935683 Common - possible vanadium nitrogenase associated protein vnfN (U51863) RPA2617 49 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39936008 Common nuoH1 NADH dehydrogenase subunit H RPA2943 191 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 39934401 Common - Ser/Thr protein kinase RPA1327 123 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 39937720 Common - putative suar transport protein RPA4662 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39937894 Common rpsT 30S ribosomal protein S20 RPA4836 159 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 39936570 Common - ATP-binding component of ABC transporter RPA3508 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 39937094 Common - ABC transporter, periplasmic branched chain amino acid binding protein RPA4034 82 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39937263 Common - putative sensor (PAS) domain for methyl-accepting chemotaxis sensory transducer RPA4203 89 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 39935066 Common cysS cysteinyl-tRNA synthetase RPA1997 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39935327 Common arsB arsenical pump membrane protein RPA2258 110 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 39934858 Common - putative branched-chain amino acid transport system substrate-binding protein RPA1789 97 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934105 Common - possible CoA transferase, subunit B RPA1030 36 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 39937436 Common lspA Signal peptidase II, family A8 RPA4376 25 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39937047 Common - putative ADP-heptose--LPS heptosyltransferase II RPA3986 96 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 39936589 Common - hypothetical protein RPA3527 7 None None None 39933563 Common - Staphylococcus nuclease (SNase-like) RPA0486 10 None None None 39934307 Common - putative branched-chain amino acid transport system ATP-binding protein RPA1232 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936847 Nonpathogen - hypothetical protein RPA3786 1 None None None 39933655 Nonpathogen - hypothetical protein RPA0578 1 None None None 39933709 Common - putative inner membrane protein translocase component YidC RPA0632 210 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 39935690 Common - putative sulfonate transport system substrate-binding protein RPA2624 108 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39935918 Common - Proline-rich region RPA2853 33 None None None 39933893 Common - putative acyl-CoA dehydrogenase RPA0816 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39934675 Common - hypothetical protein RPA1605 91 COG1262 COG1262, Uncharacterized conserved protein Function unknown 39933988 Common - transcriptional regulator, LysR family RPA0911 154 COG0583 LysR, Transcriptional regulator Transcription 39935057 Common - probable transcriptional regulator, AraC family RPA1988 125 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39935529 Common nifS1 putative cysteine desulfurase, nifS homolog RPA2463 229 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 39934726 Nonpathogen - possible urease accessory protein RPA1656 10 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 39936058 Common - hypothetical protein RPA2993 133 COG2860 COG2860, Predicted membrane protein Function unknown 39937733 Common - hypothetical protein RPA4675 90 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 39936528 Common - acetyl-CoA acetyltransferase RPA3466 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39937685 Common - hypothetical protein RPA4627 14 None None None 39934584 Common crtI phytoene dehydrogenase CrtI RPA1512 107 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39935592 Common - DUF192 RPA2526 88 COG1430 COG1430, Uncharacterized conserved protein Function unknown 39935789 Common - possible MutT-like domain RPA2722 49 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 39936202 Common - DUF482 RPA3139 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 39933172 Common - hypothetical protein RPA0092 11 None None None 39937354 Common - hypothetical protein RPA4294 13 None None None 39936676 Common - hypothetical protein RPA3614 63 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 39933675 Common - putative glutaredoxin RPA0598 111 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 39933810 Common fdsB NAD-dependent formate dehydrogenase beta subunit RPA0733 165 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 39936840 Common - hypothetical protein RPA3779 30 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39935584 Nonpathogen - hypothetical protein RPA2518 1 None None None 39937652 Common - hypothetical protein RPA4594 4 None None None 39937120 Nonpathogen - hypothetical protein RPA4060 1 None None None 39935006 Common - possible transposase RPA1937 47 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 39934366 Common - putative proteic killer suppression protein RPA1291 28 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 39935852 Common - possible flavodoxin oxidoreductase RPA2785 88 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 39935656 Common ispD 4-diphosphocytidyl-2C-methyl-D-erythritol synthase:YgbB RPA2590 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 39935921 Common - Protein of unknown function, HesB/YadR/YfhF RPA2856 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 39937154 Common - hypothetical protein RPA4094 42 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39933142 Common - hypothetical protein RPA0062 45 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 39933515 Common nusA transcription elongation factor NusA RPA0438 218 COG0195 NusA, Transcription elongation factor Transcription 39933343 Common - putative alginate o-acetyltransferase AlgI RPA0266 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 39933795 Common cobQ1 cobyric acid synthase RPA0718 152 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 39936271 Common rluC possible ribosomal large subunit pseudouridine synthase C RPA3208 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 39937851 Common QxtA cytochrome bd-quinol oxidase subunit I RPA4793 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 39935760 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ RPA2694 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 39936013 Common fkbM possible methyltransferase, FkbM family RPA2948 23 None None None 39936390 Nonpathogen - hypothetical protein RPA3327 1 None None None 39935461 Common prpC putative 2-methylcitrate synthase RPA2394 194 COG0372 GltA, Citrate synthase Energy production and conversion 39936382 Nonpathogen - hypothetical protein RPA3319 1 None None None 39933581 Common aroK putative shikimate kinase RPA0504 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 39934945 Common - putative TonB-dependent iron siderophore receptor RPA1876 120 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 39933729 Common aliB cyclohexanecarboxyl-CoA dehydrogenase RPA0652 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39935184 Common cynS cyanate hydratase RPA2115 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 39935417 Common - possible nitrogenase molybdenum-iron protein alpha chain (nitrogenase component I) (dinitrogenase) RPA2348 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39935530 Common sufB cysteine desulfurase activator complex subunit SufB RPA2464 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 39936254 Common - putative short-chain dehydrogenase RPA3191 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936860 Common - DUF182 RPA3799 111 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 39933962 Nonpathogen - hypothetical protein RPA0885 4 None None None 39934921 Common mucR putative transcriptional regulator MucR RPA1852 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 39933776 Common phnD putative PhnD protein, phosphonate ABC transporter, periplasmic binding protein precursor RPA0699 96 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 39935554 Common - hypothetical protein RPA2488 66 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39937765 Nonpathogen - hypothetical protein RPA4707 2 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 39936166 Nonpathogen - hypothetical protein RPA3103 1 None None None 39934658 Common - putative L-allo-threonine aldolase RPA1588 114 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 39936804 Common - possible phytoene synthase-related protein RPA3743 63 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 39935189 Common - putative hemin binding protein RPA2120 134 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 39934418 Common - hypothetical protein RPA1344 3 None None None 39935714 Common - hypothetical protein RPA2648 27 None None None 39934602 Common bchG bacteriochlorophyll/chlorophyll a synthase RPA1530 65 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 39936172 Common - hypothetical protein RPA3109 12 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 39937457 Common - possible substrate binding protein of ABC transporter system RPA4397 100 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935137 Nonpathogen - hypothetical protein RPA2068 3 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 39933426 Common dcm possible site-specific DNA-methyltransferase RPA0349 100 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 39933535 Common - acyl-CoA synthetase RPA0458 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936024 Common lon ATP-dependent protease Lon RPA2959 232 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 39935180 Common - PAS domain:sigma-54-dependent transcriptional regulator, Fis family RPA2111 180 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 39933327 Common dapF diaminopimelate epimerase RPA0250 185 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 39934311 Common - putative acyl-CoA dehydrogenase RPA1236 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39935197 Common exbD3 biopolymer transport protein ExbD/TolR RPA2128 136 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 39936967 Nonpathogen - hypothetical protein RPA3906 3 None None None 39936768 Common nasT putative two-component response regulator:antitermination factor NasT RPA3706 98 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 39935155 Common cobL putative precorrin 6y methylase RPA2086 94 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 39933902 Common - TldD protein, suppresses inhibitory activity of CsrA RPA0825 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 39934651 Common - hypothetical protein RPA1581 3 None None None 39933374 Common - hypothetical protein RPA0297 97 COG1981 COG1981, Predicted membrane protein Function unknown 39936926 Common - Thioesterase superfamily RPA3865 29 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39937805 Common - transcriptional regulator, LysR family RPA4747 150 COG0583 LysR, Transcriptional regulator Transcription 39937844 Common rhlG putative beta-ketoacyl reductase RPA4786 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39937248 Common - hypothetical protein RPA4188 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 39937380 Common lldA L-lactate dehydrogenase RPA4320 113 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 39933999 Common - hypothetical protein RPA0922 28 None None None 39935334 Common - hypothetical protein RPA2265 78 COG2378 COG2378, Predicted transcriptional regulator Transcription 39937483 Common - hypothetical protein RPA4423 17 None None None 39936796 Common - hypothetical protein RPA3735 75 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 39935277 Common parB2 possible ParB-like partioning protein RPA2208 136 COG1475 Spo0J, Predicted transcriptional regulators Transcription 39934574 Nonpathogen - hypothetical protein RPA1502 5 None None None 39936251 Common - alcohol dehydrogenase RPA3188 86 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 39935662 Common - D-amino acid aminotransferase RPA2596 162 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 39937329 Common - ribonuclease H RPA4269 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 39933827 Common sbp sulfate ABC transporter, periplasmic binding protein component RPA0750 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 39933767 Common phnL phosphonate ABC transporter, ATP-binding component, PhnL protein RPA0690 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 39936500 Common - hypothetical protein RPA3437 102 COG3177 COG3177, Uncharacterized conserved protein Function unknown 39935071 Common - FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal RPA2002 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 39933217 Common cheW1-3 chemotaxis signal transduction/oligomerization protein CheW1-2 RPA0140 118 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 39936911 Common gcvP glycine dehydrogenase RPA3850 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 39936331 Common rpoB DNA-directed RNA polymerase subunit beta RPA3268 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 39935143 Common - response regulator receiver (CheY-like protein) RPA2074 26 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 39934295 Common - CBS domain RPA1220 121 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 39934871 Common - hypothetical protein RPA1802 54 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 39934427 Common - hypothetical protein RPA1353 9 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 39937671 Common - DUF683 RPA4613 14 COG5420 COG5420, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 39934959 Nonpathogen - hypothetical protein RPA1890 1 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 39937557 Nonpathogen - hypothetical protein RPA4499 1 COG2445 COG2445, Uncharacterized conserved protein Function unknown 39934567 Nonpathogen - hypothetical protein RPA1495 1 None None None 39936075 Nonpathogen - hypothetical protein RPA3011 2 None None None 39934781 Common pnbA putative nitroreductase RPA1711 51 COG0778 NfnB, Nitroreductase Energy production and conversion 39935228 Nonpathogen - hypothetical protein RPA2159 1 None None None 39937008 Common - hypothetical protein RPA3947 24 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 39933629 Common dctA1 C4-dicarboxylate transporter DctA RPA0552 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 39936082 Common - response regulator receiver:histidine kinase RPA3018 176 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 39936945 Common fliR flagellar biosynthesis protein FliR RPA3884 128 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 39934108 Common - DUF85:Elongator protein 3/MiaB/NifB RPA1033 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 39936703 Common malQ putative 4-alpha-glucanotransferase RPA3641 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 39936894 Common rrm2 tRNA/rRNA methyltransferase RPA3833 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 39935875 Common - hypothetical protein RPA2808 8 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 39934472 Common - putative sugar ABC transporter, ATP-binding protein RPA1398 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 39937055 Common - putative diguanylate cyclase (GGDEF) RPA3994 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39934331 Common fmdB putative formamidase regulatory protein FmdB RPA1256 20 None None None 39936416 Common - putative serine/threonine protein phosphatase RPA3353 84 None None None 39935161 Common - hypothetical protein RPA2092 19 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 39937076 Common metK S-adenosylmethionine synthetase RPA4016 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 39936086 Common - aldo/keto reductase RPA3023 196 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 39934246 Common uvrC excinuclease ABC subunit C RPA1171 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 39933643 Nonpathogen - hypothetical protein RPA0566 9 None None None 39936434 Common - putative outer membrane protein RPA3371 30 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39937471 Common glpR glycerol-3-phosphate regulon repressor glpR, DeoR family RPA4411 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 39933615 Common - putative Omp2b porin RPA0538 18 None None None 39934222 Common - hypothetical protein RPA1147 32 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 39933588 Common - PpiC-type peptidyl-prolyl cis-trans isomerase RPA0511 171 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 39935541 Common - TfoX, N-terminal RPA2475 22 COG3070 TfoX, Regulator of competence-specific genes Transcription 39935453 Common - putative ironIII transport permease protein RPA2384 189 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 39934088 Common fixG nitrogen fixation protein fixG, homologous to rdxB of R. sphaeroides RPA1013 82 COG0348 NapH, Polyferredoxin Energy production and conversion 39934631 Common cbbX cbbX protein homolog RPA1561 59 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 39934030 Common xseB exodeoxyribonuclease VII small subunit RPA0953 142 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 39936680 Common - AAA ATPase RPA3618 93 COG0714 COG0714, MoxR-like ATPases General function prediction only 39935537 Common - hypothetical protein RPA2471 11 None None None 39934752 Common - ptwo-component transcriptional regulator, LuxR family RPA1682 224 COG4566 TtrR, Response regulator Signal transduction mechanisms 39935935 Common - L-carnitine dehydratase/bile acid-inducible protein F RPA2870 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39937665 Common nifV putative homocitrate synthase RPA4607 202 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 39934986 Common lipA1 LipA a lipoprotein RPA1917 11 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 39936813 Common - Transglutaminase-like domain RPA3752 92 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 39934951 Common - Flp/Fap pilin component RPA1882 8 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 39933841 Nonpathogen - hypothetical protein RPA0764 6 None None None 39933945 Nonpathogen - hypothetical protein RPA0868 1 None None None 39936955 Common - probable transcriptional regulator, TetR family RPA3894 89 COG1309 AcrR, Transcriptional regulator Transcription 39933381 Common - possible outer membrane lipoprotein GNA33, membrane-bound lytic murein transglycosylase RPA0304 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 39936714 Nonpathogen - hypothetical protein RPA3652 2 None None None 39935001 Common - sensor histidine kinase RPA1932 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39933467 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS domains RPA0390 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39935512 Common - putative aminotransferase RPA2446 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 39933608 Common - acetyl-CoA acetyltransferase RPA0531 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39933344 Common trx possible thioredoxin RPA0267 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 39935744 Common - putative permease protein, subunit of ABC transporter RPA2678 196 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39935797 Common thiL putative thiamine-monophosphate kinase (thiamine-phosphate kinase). RPA2730 194 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 39937839 Common phoR two component sensor histidine kinase phoR RPA4781 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 39937207 Common - thymidine phosphorylase RPA4147 129 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 39935611 Common - possible outer membrane protein RPA2545 23 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39934231 Common - putative myo-inositol monophosphatase 2 family protein RPA1156 196 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 39936985 Common - hypothetical protein RPA3924 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39936470 Nonpathogen - hypothetical protein RPA3407 2 None None None 39933368 Common parB1 chromosome partitioning protein, ParB RPA0291 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 39934723 Nonpathogen - hypothetical protein RPA1653 5 None None None 39935475 Common amiC1 putative aliphatic amidase expression-regulating protein, AmiC RPA2408 84 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39936352 Common - acyl-CoA dehydrogenase RPA3289 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39933765 Common phnN ATP-binding component, PhnN protein, possible kinase RPA0688 48 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 39935091 Common - acyl carrier protein RPA2022 51 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934372 Common - Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase RPA1297 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 39933379 Common secB preprotein translocase subunit SecB RPA0302 109 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 39936135 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II RPA3072 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39933430 Common - hypothetical protein RPA0353 32 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39937716 Common - zinc-binding dehydrogenase (related to alcohol dehydrogenase, NADPH quinone oxidoreductase) RPA4658 125 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39935126 Nonpathogen - hypothetical protein RPA2057 4 None None None 39935908 Common surE stationary phase survival protein SurE RPA2841 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 39935500 Common - sensor histidine kinase RPA2434 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 39937397 Common - putative phosphoglycolate phosphatase RPA4337 198 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 39936705 Common - putative trehalose synthase RPA3643 165 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 39934142 Common tag possible 3-methyladenine DNA glycosylase I RPA1067 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 39936452 Nonpathogen - hypothetical protein RPA3389 1 None None None 39933881 Common - hypothetical protein RPA0804 76 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 39933437 Common pckA phosphoenolpyruvate carboxykinase RPA0360 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 39933171 Nonpathogen - hypothetical protein RPA0091 1 None None None 39934712 Common - putative diguanylate cyclase (GGDEF) RPA1642 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39937177 Common trbF2 conjugal transfer protein trbF RPA4117 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 39934605 Common tspO tryptophan-rich sensory protein RPA1533 62 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 39936070 Nonpathogen - hypothetical protein RPA3005 1 None None None 39937038 Common - putative virulence factor MviN-like protein, possible efflux protein RPA3977 191 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 39937107 Common - Haloacid dehalogenase-like hydrolase RPA4047 72 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 39933557 Common - possible acyl-CoA dehydrogenase RPA0480 41 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39936140 Common rpsF 30S ribosomal protein S6 RPA3077 183 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 39933248 Common invA1 dinucleoside polyphosphate hydrolase RPA0171 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 39934338 Common - putative II.1 protein RPA1263 27 None None None 39936318 Common rpsL 30S ribosomal protein S12 RPA3255 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 39933414 Common pyrF orotidine 5'-phosphate decarboxylase RPA0337 171 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 39934512 Common nifH nitrogenase reductase RPA1438 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39935755 Common - possible thiol-specific antioxidant related protein RPA2689 83 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 39937427 Common - sensor histidine kinase RPA4367 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39934893 Common - hypothetical protein RPA1824 5 None None None 39934399 Common - putative FusE-MFP/HlyD family membrane fusion protein RPA1325 121 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39935496 Nonpathogen - hypothetical protein RPA2430 2 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 39936594 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase RPA3532 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 39937027 Nonpathogen - hypothetical protein RPA3966 5 None None None 39934068 Common - possible alpha-ribazole-5`-phosphate phosphatase CobC (vit B12 synthesis) RPA0993 126 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 39934492 Common - possible transport system permease protein RPA1418 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39937235 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit RPA4175 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 39936153 Common - putative colicin V production protein RPA3090 69 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 39933698 Common def putative N-formylmethionylaminoacyl-tRNA deformylase RPA0621 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 39936094 Nonpathogen - possible Acetyltransferase (GNAT) family RPA3031 8 COG3981 COG3981, Predicted acetyltransferase General function prediction only 39935639 Common - possible membrane protein, permease. RPA2573 164 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39934615 Common chlL protochlorophyllide reductase iron-sulfur ATP-binding protein RPA1545 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39936753 Common - putative ABC transporter, solute-binding protein RPA3691 121 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 39936363 Common - possible transcriptional regulator, TetR family RPA3300 117 COG1309 AcrR, Transcriptional regulator Transcription 39937305 Common - hypothetical protein RPA4245 41 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39937608 Nonpathogen - hypothetical protein RPA4550 2 None None None 39935864 Common - transcriptional regulator, GntR family with aminotransferase domain RPA2797 213 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 39933357 Common - hypothetical protein RPA0280 34 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 39936429 Nonpathogen - hypothetical protein RPA3366 3 None None None 39933861 Common - putative short-chain alcohol dehydrogenase-like protein RPA0784 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 39933473 Common - Cfr family protein RPA0396 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 39934620 Nonpathogen - possible photosynthetic complex assembly protein RPA1550 8 None None None 39936776 Common pimB acetyl-CoA acetyltransferase RPA3715 168 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39936323 Common - putative cation-transporting P-type ATPase RPA3260 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 39936863 Common - carbon monoxide dehydrogenase medium subunit RPA3802 91 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 39935483 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase RPA2416 199 COG0388 COG0388, Predicted amidohydrolase General function prediction only 39933868 Common exoI1 similar to Staphylococcus nuclease (SNase-like) RPA0791 59 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 39936789 Common - hypothetical protein RPA3728 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39933398 Common - two-component transcriptional regulator, LuxR family RPA0321 88 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 39935979 Common - putative outer membrane protein RPA2914 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 39935526 Common tyrS tyrosyl-tRNA synthetase RPA2460 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39937087 Common - possible branched-chain amino acid ABC transport system permease protein RPA4027 78 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934648 Common fpr ferredoxin--NADP+ reductase RPA1578 110 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 39933495 Common - glutamine amidotransferase RPA0418 134 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 39937499 Common hisC histidinol-phosphate aminotransferase RPA4439 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 39935296 Common trbL putative CONJUGAL TRANSFER protein trbL RPA2227 24 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 39936265 Common - hypothetical protein RPA3202 90 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39934465 Common - possible ABC transporter ATP-binding protein RPA1391 208 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 39934441 Common soxY1 sulfur oxidation protein SoxY RPA1367 30 COG5501 COG5501, Predicted secreted protein Function unknown 39936209 Common - hypothetical protein RPA3146 11 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39937297 Common - ATP-binding component of ABC transporter RPA4237 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 39935434 Common - putative L-allo-threonine aldolase RPA2365 115 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 39933554 Common - hypothetical protein RPA0477 31 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 39935720 Nonpathogen pucBa light harvesting protein B-800-850, beta chain A (antenna pigment protein, beta chain A) (LH II-A beta) RPA2654 7 None None None 39937776 Common modE putative molybdate transport system transcriptional regulator, ModE RPA4718 104 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 39937041 Common wbnF nucleotide sugar epimerase RPA3980 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39935455 Common - hypothetical protein RPA2386 15 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 39936542 Common fiu putative outer membrane receptor for iron transport RPA3480 107 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 39937853 Nonpathogen - hypothetical protein RPA4795 1 None None None 39933809 Common fdsG formate dehydrogenase subunit gamma RPA0732 145 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 39937788 Common - ATP-binding protein of ABC transporter, duplicated ATPase domains RPA4730 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 39933825 Common cysW possible sulfate ABC transporter, permease component RPA0748 205 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 39935891 Common - Thioesterase superfamily RPA2824 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39934814 Common - allantoate amidohydrolase RPA1745 86 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 39934967 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg8 (32% identity) RPA1898 11 None None None 39937413 Nonpathogen - hypothetical protein RPA4353 4 None None None 39935995 Common - hypothetical protein RPA2930 25 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 39936402 Common mcyE possible polyketide synthase RPA3339 242 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39935199 Common - DUF81 RPA2130 48 COG0730 COG0730, Predicted permeases General function prediction only 39933294 Common sdhA succinate dehydrogenase flavoprotein subunit RPA0217 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 39935139 Nonpathogen - hypothetical protein RPA2070 3 None None None 39934504 Common - putative outer membrane protein RPA1430 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 39933746 Common hbaA 4-hydroxybenzoate-CoA ligase RPA0669 223 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 39936798 Common - putative phosphonoacetate hydrolase RPA3737 15 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 39934938 Common - DUF81 RPA1869 44 COG0730 COG0730, Predicted permeases General function prediction only 39935099 Common miaA tRNA isopentenyltransferase RPA2030 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 39934507 Common - hypothetical protein RPA1433 11 None None None 39934824 Common ragD possible cation/heavy metal efflux pump, HlyD family secretion protein RPA1755 168 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39934477 Common - possible Glutamine amidotransferase RPA1403 50 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 39937481 Common - putative 4-coumarate:CoA ligase 2 RPA4421 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39933424 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein RPA0347 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 39933888 Common - Putative manganese transp RPA0811 92 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 39935567 Common phbC poly-beta-hydroxybutyrate synthase RPA2501 74 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 39934856 Common fcs2 feruloyl-CoA synthase RPA1787 201 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39935104 Common ilvC ketol-acid reductoisomerase RPA2035 211 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 39937824 Common metZ O-succinylhomoserine sulfhydrylase RPA4766 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 39935375 Common - Nickel-dependent hydrogenase b-type cytochrome subunit RPA2306 93 COG3038 CybB, Cytochrome B561 Energy production and conversion 39934838 Common - transcriptional regulator, LysR family RPA1769 188 COG0583 LysR, Transcriptional regulator Transcription 39934429 Common - hypothetical protein RPA1355 6 None None None 39934470 Common - possible multiple sugar transport system permease protein RPA1396 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 39934641 Common dapA1 putative dihydrodipicolinate synthetase RPA1571 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 39936643 Common - putative 8.8 KD protein Y4HR RPA3581 4 None None None 39936651 Nonpathogen - hypothetical protein RPA3589 1 None None None 39933299 Common - Beta-Ig-H3/Fasciclin domain RPA0222 68 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 39933636 Common - putative pirin RPA0559 138 COG1741 COG1741, Pirin-related protein General function prediction only 39935618 Common - hypothetical protein RPA2552 2 None None None 39937701 Common cbbT1 transketolase RPA4643 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 39935675 Common - possible monooxygenase RPA2609 124 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 39935972 Common gltA type II citrate synthase RPA2907 193 COG0372 GltA, Citrate synthase Energy production and conversion 39934729 Common - hypothetical protein RPA1659 25 COG3945 COG3945, Uncharacterized conserved protein Function unknown 39933483 Common - hypothetical protein RPA0406 18 None None None 39935835 Common rpsI 30S ribosomal protein S9 RPA2768 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 39934801 Common - similar to eukaryotic molybdopterin oxidoreductase RPA1731 116 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 39934528 Nonpathogen - hypothetical protein RPA1454 1 None None None 39937498 Common aro hypothetical protein RPA4438 31 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 39937829 Common hslO Hsp33-like chaperonin RPA4771 130 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 39933195 Common rmlC dTDP-6-deoxy-D-glucose-3,5-epimerase RPA0118 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 39936036 Common bioD dithiobiotin synthetase RPA2971 152 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 39935220 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA2151 90 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 39934422 Common fecR3 probable FecR, iron siderophore sensor protein RPA1348 37 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 39934672 Nonpathogen - hypothetical protein RPA1602 1 None None None 39937501 Common corA putative magnesium/cobalt transport protein RPA4441 153 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 39933125 Common - putative NADH dehydrogenase (ubiquinone) 1 alpha subcomplex RPA0045 100 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39937186 Common - hypothetical protein RPA4126 10 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 39937462 Nonpathogen - hypothetical protein RPA4402 1 None None None 39935947 Common - hypothetical protein RPA2882 19 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 39934669 Common - hypothetical protein RPA1599 49 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 39935685 Common - possible GMC-type oxidoreductase RPA2619 95 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 39934783 Nonpathogen - possible cyclic nucleotide-binding domain RPA1713 5 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39933219 Common cheA1 multidomain chemotaxis histidine kinase CheA1 (Hpt, CheA, & CheW domains) RPA0142 154 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 39933443 Nonpathogen - hypothetical protein RPA0366 3 None None None 39935507 Common - possible transcriptional regulator, TetR family RPA2441 32 COG1309 AcrR, Transcriptional regulator Transcription 39934191 Common - RNA polymerase sigma factor SigJ RPA1116 47 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39936229 Common - hypothetical protein RPA3166 23 COG5642 COG5642, Uncharacterized conserved protein Function unknown 39935361 Common - sensor histidine kinase RPA2292 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39935607 Common - TrapT family, dctM subunit, C4-dicarboxylate transport RPA2541 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 39934571 Nonpathogen - hypothetical protein RPA1499 2 None None None 39937284 Nonpathogen - hypothetical protein RPA4224 4 None None None 39933307 Common asdB aspartate-semialdehyde dehydrogenase RPA0230 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 39937276 Common glcB malate synthase G RPA4216 77 COG2225 AceB, Malate synthase Energy production and conversion 39936065 Common kdpE two-component osmotic transcriptional regulator kdpE, winged helix family RPA3000 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39936498 Common - Glycosyl transferase, family 2 RPA3435 16 None None None 39934403 Common fumC fumarate hydratase RPA1329 218 COG0114 FumC, Fumarase Energy production and conversion 39936534 Common ilvD1 dihydroxy-acid dehydratase RPA3472 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 39933691 Common - hypothetical protein RPA0614 66 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 39933753 Common - enoyl-CoA hydratase RPA0676 14 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39933939 Common - G-protein beta WD-40 repeat RPA0862 46 COG2319 COG2319, FOG: WD40 repeat General function prediction only 39933469 Common argG argininosuccinate synthase RPA0392 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 39933641 Common - hypothetical protein RPA0564 13 COG5528 COG5528, Predicted integral membrane protein Function unknown 39934701 Common cheR2 chemotaxis methyltransferase, CheR2 RPA1631 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 39936881 Common - phosphoribosylformylglycinamidine synthase subunit PurS RPA3820 58 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 39935200 Common - hypothetical protein RPA2131 6 None None None 39933096 Common ccoP cytochrome-c oxidase fixP chain RPA0016 78 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 39935219 Common - putative oxidoreductase RPA2150 184 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 39937804 Common - putative NAD(P)H quinone reductase RPA4746 90 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 39935809 Common himA integration host factor alpha subunit RPA2742 193 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 39937252 Common - hypothetical protein RPA4192 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 39933221 Common - Sulfate transporter/antisigma-factor antagonist domain RPA0144 3 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 39934458 Common ptxC putative phosphate permease component of ATP-dependent phosphate uptake system RPA1384 86 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 39935927 Common exoR putative exopolysaccharide regulatory protein exoR RPA2862 82 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 39937790 Common - uncharacterized cation transport protein chaC RPA4732 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 39935555 Common - hypothetical protein RPA2489 11 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 39935896 Common - hypothetical protein RPA2829 29 COG3737 COG3737, Uncharacterized conserved protein Function unknown 39937149 Common - Patatin-like phospholipase domain RPA4089 10 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 39935767 Common - hypothetical protein RPA2701 79 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39935084 Nonpathogen - hypothetical protein RPA2015 1 None None None 39937645 Common - hypothetical protein RPA4587 16 None None None 39933212 Common - possible oxidoreductase RPA0135 208 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 39935625 Common metC cystathionine beta-lyase RPA2559 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 39935132 Common nosF putative NosF protein (an ABC transporter) RPA2063 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 39936850 Common - putative ATP-binding component of a transport system RPA3789 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 39937344 Common - YceI like family RPA4284 117 COG2353 COG2353, Uncharacterized conserved protein Function unknown 39936467 Common - putative O-methyltransferase RPA3404 77 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 39933834 Nonpathogen - hypothetical protein RPA0757 2 None None None 39937383 Nonpathogen - hypothetical protein RPA4323 1 None None None 39937541 Common - methyl-accepting chemotaxis sensory transducer RPA4481 143 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39933303 Common - Major Facilitator Family (MFS) transporter RPA0226 25 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936490 Common - hypothetical protein RPA3427 9 None None None 39935283 Common - possible helicase RPA2214 65 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 39935232 Common - SEC-C motif RPA2163 91 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 39936858 Common - hypothetical protein RPA3797 142 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 39934456 Common - Nitrogen fixation-related protein RPA1382 20 None None None 39937340 Common - probable transcriptional regulator, AraC family RPA4280 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39937643 Common - Lipopolysaccharide biosynthesis RPA4585 63 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 39935540 Common - possible o-linked GlcNac transferase RPA2474 133 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 39933206 Common - putative sugar binding protein of ABC transporter RPA0129 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 39937869 Common - hypothetical protein RPA4811 51 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 39935489 Common - probable transcriptional regulator, AraC family RPA2423 144 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39935266 Common - cell division protein FtsJ RPA2197 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 39935700 Common nifB1 putative nitrogenase iron-molybdenum cofactor biosynthesis protein NifB RPA2634 106 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 39935803 Common mexD2 RND multidrug efflux transporter MexD RPA2736 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39936729 Common - possible permease of ABC transporter RPA3667 159 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39935217 Common - Beta-lactamase RPA2148 141 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 39936630 Nonpathogen - hypothetical protein RPA3568 3 COG1873 COG1873, Uncharacterized conserved protein Function unknown 39933578 Common - BolA-like protein RPA0501 103 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 39936211 Common clpS ATP-dependent Clp protease adaptor protein ClpS RPA3148 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 39934202 Common - probable branched-chain amino acid transport protein AzlC RPA1127 77 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 39937205 Common nirK2 dissimilatory nitrite reductase RPA4145 58 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 39933386 Common hisB imidazoleglycerol-phosphate dehydratase RPA0309 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 39934162 Common - possible transglycosylase SLT domain RPA1087 78 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 39937590 Common - hypothetical protein RPA4532 20 None None None 39936196 Common - response regulator receiver (CheY-like protein) RPA3133 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 39937814 Common - nickel responsive regulator RPA4756 64 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 39937563 Nonpathogen - TPR repeat RPA4505 4 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 39935547 Common - possible transcriptional regulator, XRE family RPA2481 41 COG1396 HipB, Predicted transcriptional regulators Transcription 39933392 Common coaA pantothenate kinase RPA0315 70 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 39934692 Common - hypothetical protein RPA1622 88 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 39937508 Common - RNA polymerase sigma factor RPA4448 146 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39933785 Nonpathogen - hypothetical protein RPA0708 1 None None None 39937367 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4307 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39935911 Common - hypothetical protein RPA2846 9 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 39936113 Common - CDP-alcohol phosphatidyltransferase RPA3050 93 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 39936222 Common - probable glutathione S-transferase RPA3159 73 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39933462 Common radC DNA repair protein RadC RPA0385 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 39934192 Common TolQ TolQ protein, inner membrane protein, tolerance to group A colicins RPA1117 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39933141 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase RPA0061 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 39935278 Common - ParB-like nuclease RPA2209 28 COG1475 Spo0J, Predicted transcriptional regulators Transcription 39936104 Common - hypothetical protein RPA3041 15 COG2259 COG2259, Predicted membrane protein Function unknown 39935403 Common - hypothetical protein RPA2334 2 None None None 39937662 Common fixB electron transfer flavoprotein alpha chain protein fixB RPA4604 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 161610778 Common gltA putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin domain-containing protein RPA0678 204 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 39934152 Common - Sua5/YciO/YrdC/YwlC protein family:SUA5 domain RPA1077 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 39934436 Common - putative sulfate ester transport system substrate-binding protein RPA1362 72 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39933279 Common acnA aconitate hydratase RPA0202 223 COG1048 AcnA, Aconitase A Energy production and conversion 39934367 Nonpathogen - hypothetical protein RPA1292 1 None None None 39935336 Common - hypothetical protein RPA2267 3 None None None 39935651 Common - hypothetical protein RPA2585 9 None None None 39935713 Common - putative hydrolase RPA2647 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 39934306 Common - possible ABC transporter, permease protein RPA1231 164 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39936640 Nonpathogen - hypothetical protein RPA3578 4 None None None 39936913 Common - hypothetical protein RPA3852 4 None None None 39935271 Common - SUN-family protein, putative RNA methyltransferase RPA2202 203 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 39934379 Common - possible flagellar basal-body rod modification protein FlgD RPA1304 73 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 39934975 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg14 RPA1906 16 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 39936296 Common rpsE 30S ribosomal protein S5 RPA3233 246 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 39934073 Common - hypothetical protein RPA0998 69 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 39937635 Common - putative permease protein of sugar ABC transporter RPA4577 105 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 39935549 Nonpathogen - hypothetical protein RPA2483 4 None None None 39937729 Common maiA putative maleylacetoacetate isomerase RPA4671 90 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39933126 Common - 3'-5' exonuclease RPA0046 116 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 39933901 Common lepB1 signal peptidase I RPA0824 200 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 39936602 Common - putative cell filamentation protein RPA3540 37 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 39936629 Nonpathogen - hypothetical protein RPA3567 5 None None None 39933743 Common hbaG putative ABC transporter subunit, membrane spanning domain + ATP-binding component RPA0666 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39934488 Common - MaoC-like dehydratase RPA1414 33 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39936147 Common dnaB replicative DNA helicase RPA3084 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 39933528 Common rimI putative RimI protein, peptide N-acetyltransferase RPA0451 189 COG0456 RimI, Acetyltransferases General function prediction only 39935207 Common - putative acyl-CoA dehydrogenase RPA2138 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39936564 Common - hypothetical protein RPA3502 15 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 39933967 Nonpathogen - hypothetical protein RPA0890 2 None None None 39936838 Common - possible transcriptional regulator, TetR family RPA3777 66 COG1309 AcrR, Transcriptional regulator Transcription 39935408 Common - transcriptional regulator, FUR family; possible iron response regulator IRR RPA2339 152 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 39935876 Common - Beta-lactamase RPA2809 138 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 39935637 Common - possible NADPH-dependent oxidoreductase RPA2571 69 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 39935446 Common - hypothetical protein RPA2377 18 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 39935729 Common Mfd transcription repair coupling factor RPA2663 217 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 39934647 Nonpathogen - hypothetical protein RPA1577 4 None None None 39937677 Common nifD nitrogenase molybdenum-iron protein alpha chain, nifD RPA4619 51 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39937170 Common mycA myosin-crossreactive antigen RPA4110 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 39937268 Common - SCP-like extracellular protein RPA4208 45 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 39933334 Nonpathogen - hypothetical protein RPA0257 3 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 39937337 Common - hypothetical protein RPA4277 29 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 39934693 Common - hypothetical protein RPA1623 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 39936422 Common - O-antigen polymerase RPA3359 13 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 39936733 Common infA translation initiation factor if-1 (infA) RPA3671 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 39934539 Common - transcriptional regulator, GntR family RPA1467 142 COG1802 GntR, Transcriptional regulators Transcription 39935387 Common gctA possible glutaconate CoA-transferase, subunit A RPA2318 35 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 39936770 Common - Globin-like protein RPA3708 48 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 39934043 Common hupG putative hydrogenase expression/formation protein hupG RPA0968 9 None None None 39936021 Common mexF putative RND multidrug efflux transporter MexF RPA2956 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39934125 Nonpathogen - hypothetical protein RPA1050 1 None None None 39934253 Common hisS histidyl-tRNA synthetase RPA1178 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39933188 Common - Possible benzaldehyde lyase RPA0108 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39934346 Common - hypothetical protein RPA1271 8 None None None 39935386 Common gctB putative CoA transferase, small subunit B RPA2317 74 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 39937657 Nonpathogen - hypothetical protein RPA4599 3 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934053 Common hypE hydrogenase expression/formation protein hypE RPA0978 144 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 39935245 Common - DUF403 RPA2176 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 39937231 Common - hypothetical protein RPA4171 15 COG5570 COG5570, Uncharacterized small protein Function unknown 39935843 Common - DNA polymerase III subunit delta' RPA2776 215 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 39933929 Common - two-component transcriptional regulator, LuxR family RPA0852 203 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 39935814 Nonpathogen - hypothetical protein RPA2747 1 None None None 39933982 Nonpathogen - Flp/Fap pilin component RPA0905 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 39934318 Nonpathogen - hypothetical protein RPA1243 3 None None None 39934309 Common - possible long-chain-fatty-acid--CoA ligase RPA1234 197 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 39935660 Common ntrY nitrogen regulatory signal transduction histidine kinase NtrY RPA2594 207 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 39933730 Common badI 2-ketocyclohexanecarboxyl-CoA hydrolase RPA0653 179 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 39936468 Common - possible transporter RPA3405 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39933627 Common - RNA polymerase sigma factor RpoE RPA0550 114 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39935421 Common - hypothetical protein RPA2352 36 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 39937743 Common lysK lysyl-tRNA synthetase RPA4685 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 39933653 Common - putative metal-dependent hydrolase RPA0576 154 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 39933884 Common - possible ATP dependent DNA helicase RPA0807 125 COG1201 Lhr, Lhr-like helicases General function prediction only 39934107 Common - Glycosyl transferase, family 2 RPA1032 20 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39934235 Common - hypothetical protein RPA1160 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 39935764 Common era GTP-binding protein Era RPA2698 233 COG1159 Era, GTPase General function prediction only 39936544 Common - hypothetical protein RPA3482 141 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39935051 Common - hypothetical protein RPA1982 15 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 39934626 Common - phosphotransfer protein with response regulator receiver and Hpt domains RPA1556 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39933712 Common - sensor histidine kinase RPA0635 133 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39933548 Common - putative creatine amidohydrolase RPA0471 85 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 39937198 Nonpathogen - hypothetical protein RPA4138 9 COG5490 COG5490, Uncharacterized conserved protein Function unknown 39936825 Common - putative 2Fe:2S ferredoxin RPA3764 157 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 39937615 Common - hypothetical protein RPA4557 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 39936026 Common clpP ATP-dependent Clp protease proteolytic subunit RPA2961 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 39933225 Common - hypothetical protein RPA0148 16 None None None 39934799 Common - Fatty acid desaturase family RPA1729 29 COG3239 DesA, Fatty acid desaturase Lipid metabolism 39933807 Common - hypothetical protein RPA0730 14 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39936943 Common cckA sensor histidine kinase with multiple PAS and a response regulator receiver domain RPA3882 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39935287 Common - possible ATP-dependent RNA helicase RPA2218 171 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 39933620 Common - hypothetical protein RPA0543 9 None None None 39934868 Common ung Uracil-DNA glycosylase:Phage SPO1 DNA polymerase-related protein RPA1799 161 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 39934110 Common - hypothetical protein RPA1035 7 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39937138 Common - hypothetical protein RPA4078 12 None None None 39933223 Nonpathogen - hypothetical protein RPA0146 1 None None None 39935599 Nonpathogen - hypothetical protein RPA2533 1 None None None 39933875 Common - Beta-lactamase-like RPA0798 113 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 39935980 Common - Zinc metalloprotease RPA2915 218 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 39934216 Common groES co-chaperonin GroES RPA1141 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 39933533 Common - possible mviN family virulence factors, possible efflux protein RPA0456 165 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 39936335 Common rplA 50S ribosomal protein L1 RPA3272 243 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 39936069 Common kdpA potassium-transporting ATPase subunit A RPA3004 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 39937586 Common - hypothetical protein RPA4528 32 COG4637 COG4637, Predicted ATPase General function prediction only 39936187 Common TopA DNA topoisomerase I RPA3124 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 39933264 Common - hypothetical protein RPA0187 13 COG3686 COG3686, Predicted membrane protein Function unknown 39934269 Common - putative carboxymethylenebutenolidase RPA1194 110 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 39935008 Common - possible cation efflux protein RPA1939 208 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 39934364 Nonpathogen - hypothetical protein RPA1289 1 None None None 39934273 Common - putative heat shock protein DnaJ RPA1198 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 39934860 Common - branched-chain amino acid transport system ATP-binding protein RPA1791 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935431 Common - putative O-acetylhomoserine sulfhydrylase RPA2362 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 39934705 Common - RNA polymerase ECF-type sigma factor RPA1635 123 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39936536 Common fabG4 putative 3-oxoacyl-acyl carrier protein reductase RPA3474 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39937775 Common modA molybdate transport system substrate-binding protein RPA4717 128 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 39936572 Nonpathogen - hypothetical protein RPA3510 1 None None None 39933517 Common - hypothetical protein RPA0440 10 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 39937752 Common - hypothetical protein RPA4694 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 39933797 Common - putative ABC-type cobalamin/Fe3+-siderophores transport systems, periplasmic components RPA0720 23 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 39937884 Common recQ DNA helicase RPA4826 223 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 39933252 Common atpC putative H+-transporting ATP synthase epsilon chain. RPA0175 179 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 39936215 Nonpathogen - hypothetical protein RPA3152 8 None None None 39937333 Nonpathogen - hypothetical protein RPA4273 1 None None None 39933789 Common cobT putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase RPA0712 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 39937599 Common rlgA DNA invertase gene rlgA RPA4541 134 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 39937858 Common - possible transporter RPA4800 43 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39933275 Common - possible acetate transporter, stationary-phase anti-death (SAD) family RPA0198 120 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 39937019 Common - hypothetical protein RPA3958 81 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 39934755 Common - possible serine protease/outer membrane autotransporter RPA1685 52 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 39937641 Common - possible UDP-N-acetyl-D-mannosamine transferase RPA4583 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 39935448 Common - probable acetyltransferase RPA2379 72 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 39933679 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA0602 23 None None None 39936634 Nonpathogen - hypothetical protein RPA3572 14 None None None 39933100 Common panE1 2-dehydropantoate 2-reductase RPA0020 73 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 39934494 Common ybdE putative inner membrane component for iron transport RPA1420 179 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 39935790 Common - hypothetical protein RPA2723 8 None None None 39937161 Common - putative organic hydroperoxide resistance protein RPA4101 85 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 39936387 Nonpathogen - hypothetical protein RPA3324 3 None None None 39935780 Common - hypothetical protein RPA2713 13 None None None 39934328 Common - branched-chain amino acid transport system ATP-binding protein RPA1253 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 39934771 Common - hypothetical protein RPA1701 9 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 39933084 Common gyrB DNA gyrase subunit B RPA0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 39936062 Common - hypothetical protein RPA2997 3 None None None 39937044 Common - putative nucleotide sugar epimerase/dehydratase RPA3983 150 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39934275 Common - possible phosphoglycerate mutase RPA1200 119 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 39933584 Common - possible cytochrome b561 RPA0507 24 COG3038 CybB, Cytochrome B561 Energy production and conversion 39937423 Common ribH riboflavin synthase subunit beta RPA4363 116 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 39936240 Nonpathogen - hypothetical protein RPA3177 3 None None None 39933352 Common amtB2 putative ammonium transporter AmtB RPA0275 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 39934741 Common - putative serine/threonine protein kinase RPA1671 137 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 39935633 Common - possible EA31 gene protein, phage lambda RPA2567 9 None None None 39937110 Common - hypothetical protein RPA4050 6 None None None 39935600 Common - hypothetical protein RPA2534 3 COG0582 XerC, Integrase DNA replication, recombination, and repair 39936441 Nonpathogen - hypothetical protein RPA3378 1 None None None 39934007 Common - possible 3-octaprenyl-4-hydroxybenzoate carboxy-lyase RPA0930 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 39934285 Common - hypothetical protein RPA1210 33 COG0714 COG0714, MoxR-like ATPases General function prediction only 39937361 Nonpathogen - hypothetical protein RPA4301 1 None None None 39934220 Common - ErfK/YbiS/YcfS/YnhG RPA1145 87 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39937066 Nonpathogen - hypothetical protein RPA4006 1 None None None 39934638 Common - possible carboxylesterase RPA1568 180 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39937318 Common nuoH2 NADH-ubiquinone dehydrogenase chain H RPA4258 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 39937613 Common - possible TrapT family, dctQ subunit, C4-dicarboxylate transport RPA4555 10 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 39936932 Common mes-4 Nuclear protein SET RPA3871 24 COG2940 COG2940, Proteins containing SET domain General function prediction only 39936357 Common - putative branched-chain amino acid transport system ATP-binding protein RPA3294 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936170 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A RPA3107 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39935050 Common cbbI ribose-5-phosphate isomerase A RPA1981 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 39936578 Common - possible bcr efflux pump, Major Facilitator Superfamily (MFS) RPA3516 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936278 Common - putative nitroreductase RPA3215 92 COG0778 NfnB, Nitroreductase Energy production and conversion 39936367 Common fabG3 putative 3-oxoacyl-acyl carrier protein reductase RPA3304 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936957 Nonpathogen - hypothetical protein RPA3896 8 None None None 39933904 Common - hypothetical protein RPA0827 9 COG4634 COG4634, Uncharacterized protein conserved in bacteria Function unknown 39936245 Common phzF Phenazine biosynthesis PhzC/PhzF protein RPA3182 122 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 39937794 Common ftsE putative cell division ATP-binding protein FtsE, ABC type transporter RPA4736 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 39936522 Nonpathogen - hypothetical protein RPA3460 3 None None None 39937129 Common - methionine sulfoxide reductase B RPA4069 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 39936161 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase RPA3098 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 39934416 Nonpathogen - hypothetical protein RPA1342 1 None None None 39937144 Common - AAA ATPase RPA4084 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 39934376 Common pfpI putative intracellular protease, PfpI family RPA1301 173 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 39937722 Common - CUPIN domain:transcriptional regulator, AraC family RPA4664 117 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39936514 Common - possible transcriptional regulator, TetR family RPA3451 64 COG1309 AcrR, Transcriptional regulator Transcription 39936287 Common - putative short-chain dehydrogenase RPA3224 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39933741 Nonpathogen badL possible acetyltransferase RPA0664 7 COG0456 RimI, Acetyltransferases General function prediction only 39935320 Common - putative plasmid stabilization protein RPA2251 130 COG1475 Spo0J, Predicted transcriptional regulators Transcription 39934739 Nonpathogen - hypothetical protein RPA1669 2 None None None 39934796 Common - putative oxidoreductase RPA1726 179 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39935329 Common - possible Viral (Superfamily 1) RNA helicase RPA2260 136 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 39937291 Common - putative oxidoreductase RPA4231 177 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 39933325 Common bp26 DUF541 RPA0248 106 COG2968 COG2968, Uncharacterized conserved protein Function unknown 39934297 Common - hypothetical protein RPA1222 23 COG5607 COG5607, Uncharacterized conserved protein Function unknown 39933241 Common proA gamma-glutamyl phosphate reductase RPA0164 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 39934015 Common - hypothetical protein RPA0938 102 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 39934734 Common - Glyoxalase/Bleomycin resistance protein/dioxygenase domain RPA1664 52 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 39934916 Common - hypothetical protein RPA1847 4 None None None 39935722 Nonpathogen - hypothetical protein RPA2656 5 None None None 39935170 Common - hypothetical protein RPA2101 100 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 39933595 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA0518 151 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 39935018 Common pqqD pyrroloquinoline quinone biosynthesis protein D RPA1949 20 None None None 39936587 Common ddlA putative D-alanyl-D-alanine ligase A RPA3525 209 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 39934064 Common - putative ATP-binding component of ABC transporter RPA0989 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39933953 Common - hypothetical protein RPA0876 215 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 39935752 Common dapA dihydrodipicolinate synthase RPA2686 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 39935349 Common - putative low-affinity phosphate transport accessory protein RPA2280 69 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 39934092 Nonpathogen - Nitrogen fixation-related protein RPA1017 12 COG1433 COG1433, Uncharacterized conserved protein Function unknown 39935044 Common - periplasmic mannitol-binding protein, SmoM; possible Trap-T transport system, dctP subunit RPA1975 93 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 39933560 Nonpathogen - hypothetical protein RPA0483 4 None None None 39935776 Common - possible FusE-MFP/HlyD family membrane fusion protein RPA2709 99 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39935332 Common - possible plasmid stabilization protein RPA2263 58 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 39937864 Common - hypothetical protein RPA4806 12 COG0439 AccC, Biotin carboxylase Lipid metabolism 39937365 Nonpathogen - hypothetical protein RPA4305 2 None None None 39936016 Common nuoB1 NADH dehydrogenase subunit B RPA2951 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 39933720 Nonpathogen - hypothetical protein RPA0643 2 None None None 39937131 Common carB carbamoyl phosphate synthase large subunit RPA4071 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 39934979 Common - hypothetical protein RPA1910 8 None None None 39934662 Common murI glutamate racemase RPA1592 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 39933107 Common aroG1 phospho-2-dehydro-3-heoxyheptonate aldolase RPA0027 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 39934025 Common - possible hypothetical RNA methyltransferase RPA0948 189 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 39937355 Common purA adenylosuccinate synthetase RPA4295 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 39933403 Common - DUF24, predicted transcriptional regulator, related to MarR family RPA0326 138 COG1733 COG1733, Predicted transcriptional regulators Transcription 39934569 Common mexC1 putative RND multidrug efflux membrane fusion protein MexC precursor RPA1497 145 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39936658 Common - hypothetical protein RPA3596 47 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 39936874 Common - Peptidase family T4 RPA3813 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936089 Nonpathogen - similar to abortive infection protein RPA3026 8 None None None 39935837 Common - hypothetical protein RPA2770 32 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 39934256 Common - Haloacid dehalogenase-like hydrolase RPA1181 67 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 39934244 Common moaD molybdopterin converting factor, subunit 1 RPA1169 64 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 39937307 Common fixL two component low oxygen sensor histidine kinase with PAS domains, fixL RPA4247 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39933110 Common - Bacterial Sun/eukaryotic nucleolar Nop1/Nop2 RPA0030 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 39933768 Common phnK phosphonates transport ATP-binding protein RPA0691 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 39936073 Common kup2 potassium uptake protein Kup RPA3008 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 39935314 Nonpathogen - hypothetical protein RPA2245 10 None None None 39933333 Common - putative UROPORPHYRINOGEN-III synthase RPA0256 40 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 39933117 Common pheS phenylalanyl-tRNA synthetase subunit alpha RPA0037 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 39933613 Common - Acyltransferase 3 family RPA0536 25 COG4763 COG4763, Predicted membrane protein Function unknown 39937261 Nonpathogen - hypothetical protein RPA4201 2 None None None 39934907 Common folK putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase RPA1838 201 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 39936918 Common - possible esterase/lipase/outer membrane autotransporter RPA3857 32 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 39936558 Nonpathogen - possible TctB subunit of the Tripartite Tricarboxylate Transport(TTT) Family RPA3496 4 None None None 39937712 Common - hypothetical protein RPA4654 66 COG2128 COG2128, Uncharacterized conserved protein Function unknown 39934928 Common - hypothetical protein RPA1859 9 None None None 39937223 Common - putative taurine transport system ATP-binding protein RPA4163 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39935873 Common nthB putative nitrile hydratase beta subunit RPA2806 18 None None None 39936111 Common - polyphosphate kinase RPA3048 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 39934300 Common - possible pyruvate ferredoxin/flavodoxin oxidoreductas 4Fe-4S binding domain RPA1225 75 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 39933131 Common - putative sigma-54 modulation protein RPA0051 97 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 39934594 Common bchX bacteriochlorophyllide reductase subunit BchX RPA1522 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39937673 Common nifX nitrogenase molybdenum-iron protein nifX RPA4615 32 None None None 39933565 Common - possible CarD-like transcriptional regulator RPA0488 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 39934018 Common - hypothetical protein RPA0941 32 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 39937678 Common nifH nitrogenase reductase RPA4620 91 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39933667 Common prc putative carboxyl-terminal protease RPA0590 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 39935701 Common nifH3 putative nitrogenase reductase NifH subunit RPA2635 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 39937624 Common ackA putative acetate kinase RPA4566 161 COG0282 ackA, Acetate kinase Energy production and conversion 39933978 Common - DUF81 RPA0901 24 COG0730 COG0730, Predicted permeases General function prediction only 39934233 Common - putative 3-deoxy-D-manno-octulosonic-acid transferase RPA1158 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 39935254 Common - nodN-like protein RPA2185 70 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39937179 Nonpathogen - hypothetical protein, possible TrbK RPA4119 1 None None None 39934036 Common hupU uptake hydrogenase accessory protein hupU RPA0959 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 39936084 Common - probable transcriptional regulator TetR family RPA3021 90 COG1309 AcrR, Transcriptional regulator Transcription 39936582 Common - hypothetical protein RPA3520 129 COG4105 ComL, DNA uptake lipoprotein General function prediction only 39933132 Common ptsN1 putative nitrogen regulatory IIA protein RPA0052 130 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 39933559 Common - probable short chain 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase RPA0482 169 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936896 Nonpathogen - hypothetical protein RPA3835 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 39936987 Common - putative sugar-nucleotide epimerase/dehydratase RPA3926 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39937569 Common - Major Facilitator Superfamily (MFS) transporter RPA4511 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39933174 Nonpathogen - hypothetical protein RPA0094 4 None None None 39933895 Common - probable 3-hydroxyacyl-CoA dehydrogenase RPA0818 178 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 39934119 Nonpathogen - hypothetical protein RPA1044 1 None None None 39934582 Common - hypothetical protein RPA1510 20 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39934229 Common - hypothetical protein RPA1154 8 None None None 39937845 Common - anaerobic benzoate catabolism transcriptional regulator RPA4787 192 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 39934500 Common - ABC transporter, ATP-binding protein RPA1426 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 39933650 Common - putative ABC transporter (ATP-binding protein) RPA0573 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 39933346 Common - DUF343 RPA0269 104 COG2835 COG2835, Uncharacterized conserved protein Function unknown 39936809 Common - Elongator protein 3/MiaB/NifB RPA3748 84 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 39935613 Nonpathogen - hypothetical protein RPA2547 1 None None None 39937687 Common ferN ferredoxin 2[4Fe-4S], fdxN RPA4629 100 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 39934953 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA1884 164 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39937172 Common - putative diguanylate cyclase (GGDEF) RPA4112 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39937001 Common - Universal stress protein (Usp) RPA3940 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39936742 Common - possible pilus assembly protein cpaE RPA3680 33 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 39935759 Common relA GTP pyrophosphokinase RPA2693 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 39934445 Common vnfX putative vanadium nitrogenase protein RPA1371 26 None None None 39935194 Common - hypothetical protein RPA2125 37 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 39935519 Common prfB translation peptide releasing factor RF-2 RPA2453 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 39937090 Nonpathogen - hypothetical protein RPA4030 3 None None None 39933433 Common - PTS system Hpr Kinase RPA0356 37 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 39937228 Common - NAD binding site:FAD dependent oxidoreductase RPA4168 93 COG0579 COG0579, Predicted dehydrogenase General function prediction only 39936716 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A RPA3654 58 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 39935795 Common ribH riboflavin synthase subunit beta RPA2728 210 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 39937837 Common pstC phosphate ABC transporter, permease protein, PstC RPA4779 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 39937667 Common nifU putative nifU protein RPA4609 131 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 39936965 Common mexC3 putative RND multidrug efflux membrane fusion protein MexC precursor RPA3904 151 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39935186 Common - flavodoxin FldA RPA2117 70 COG0716 FldA, Flavodoxins Energy production and conversion 39935892 Common - hypothetical protein RPA2825 18 None None None 39935521 Common - Peptidase M23/M37 RPA2455 195 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 39937891 Common - possible polysaccharide export protein RPA4833 92 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 39936962 Common flgA flagellar basal body P-ring biosynthesis protein FlgA RPA3901 47 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 39935190 Nonpathogen - hypothetical protein RPA2121 3 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 39934392 Common cioB putative cytochrome bd-I oxidase subunit II RPA1319 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 39933859 Nonpathogen - hypothetical protein RPA0782 3 None None None 39936924 Common - transcriptional regulator, Crp/Fnr family RPA3863 91 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39937763 Common hisE2 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase RPA4705 162 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 39935298 Common trbJ putative conjugal transfer protein trbJ RPA2229 24 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 39935535 Common - putative lactoylglutathione lyase RPA2469 24 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 39936168 Common - Patatin-like phospholipase domain RPA3105 15 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 39935124 Common - possible RND divalent metal cation efflux membrane fusion protein CzcB precursor RPA2055 141 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39933774 Common phnE1 putative PhnE protein, phosphonate ABC transporter, permease component RPA0697 87 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 39936256 Common - DUF35 RPA3193 56 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 39937374 Common gstA2 possible glutathione S-transferase RPA4314 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39935594 Nonpathogen - hypothetical protein RPA2528 1 None None None 39937595 Common - hypothetical protein RPA4537 22 None None None 39937650 Common - acyl-CoA synthetase RPA4592 211 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934037 Common hupS hydrogenase small chain RPA0962 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 39936678 Common - putative diguanylate cyclase (GGDEF) with PAS/PAC domain RPA3616 183 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39933803 Common btaB putative BtaB protein, S-adenosylmethionine:diacylgycerolhomoserine-N-methyltransf erase RPA0726 44 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39936384 Common algC possible phosphomannomutase AlgC RPA3321 195 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 39933822 Common - possible outer membrane protein precursor RPA0745 5 None None None 39933665 Common - transcriptional regulator, TetR family RPA0588 13 COG1309 AcrR, Transcriptional regulator Transcription 39935023 Common - probable transcriptional regulator, TetR family RPA1954 96 COG1309 AcrR, Transcriptional regulator Transcription 39936885 Common - hypothetical protein RPA3824 20 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 39937760 Common ligB Protocatechuate 4,5-dioxygenase, beta chain RPA4702 30 COG3384 COG3384, Uncharacterized conserved protein Function unknown 39936980 Common - possible mannose-1-phosphate guanyltransferase RPA3919 131 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 39933236 Common rpmA 50S ribosomal protein L27 RPA0159 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 39937126 Nonpathogen - hypothetical protein RPA4066 2 None None None 39936439 Common - possible DNA methyltransferase RPA3376 28 COG4889 COG4889, Predicted helicase General function prediction only 39937075 Common ahcY S-adenosyl-L-homocysteine hydrolase RPA4015 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 39933964 Common exoN UTP-glucose-1-phosphate uridylyltransferase RPA0887 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 39936555 Common thyA thymidylate synthase RPA3493 143 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 39934617 Common lhaA photosynthetic complex (LH1) assembly protein LhaA, probable Major Facilitator Superfamily (MFS) transporter RPA1547 23 None None None 39933700 Common truA tRNA pseudouridine synthase A RPA0623 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 39934545 Common - possible peptide transport system substrate-binding protein RPA1473 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39937692 Common - hypothetical protein RPA4634 24 None None None 39935903 Common - possible hydrolase RPA2836 37 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39934943 Nonpathogen - hypothetical protein RPA1874 1 None None None 39936671 Common - putative ABC transporter ATP-binding protein RPA3609 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 39933541 Common - putative long-chain fatty-acid-CoA ligase RPA0464 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39937832 Common - hypothetical protein RPA4774 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 39935733 Common - hypothetical protein RPA2667 14 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 39935073 Common - hypothetical protein RPA2004 107 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 39937442 Nonpathogen - hypothetical protein RPA4382 3 None None None 39935518 Common - putative penicillin-binding protein 1A RPA2452 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 39933672 Common - hypothetical protein RPA0595 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39935885 Nonpathogen - hypothetical protein RPA2818 3 None None None 39934887 Common - putative diguanylate cyclase (GGDEF) RPA1818 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39936106 Common aspS aspartyl-tRNA synthetase RPA3043 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39937867 Common - putative ABC transporter, ATP-binding protein RPA4809 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 39936802 Common - putative oxidoreductase RPA3741 30 COG3349 COG3349, Uncharacterized conserved protein Function unknown 39933089 Common kaiC circadian clock protein KaiC RPA0009 157 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 39934554 Common - hypothetical protein RPA1482 6 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 39936794 Common - hypothetical protein RPA3733 64 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 39934998 Common - htrA-like serine protease RPA1929 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39933829 Common cysD sulfate adenylyltransferase subunit 2 RPA0752 137 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 39936998 Common - methionine sulfoxide reductase B RPA3937 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 39935436 Common - two component sensor histidine kinase, possible AdeS RPA2367 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39937724 Common coxS carbon-monoxide dehydrogenase small subunit RPA4666 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 39936596 Common murF putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- D-alanyl-D-alanine ligase RPA3534 207 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 39937807 Common etfA electron transfer flavoprotein alpha-subunit, (ETFLS) RPA4749 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 39934576 Common - hypothetical protein RPA1504 41 COG4949 COG4949, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 39937006 Nonpathogen - hypothetical protein RPA3945 4 COG5373 COG5373, Predicted membrane protein Function unknown 39935415 Common - hypothetical protein RPA2346 11 COG3391 COG3391, Uncharacterized conserved protein Function unknown 39935182 Common nrtB possible nitrate transport system permease protein RPA2113 196 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39935669 Common - hypothetical protein RPA2603 9 None None None 39935037 Common - RND efflux transporter RPA1968 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39936238 Common - propionyl-CoA carboxylase precursor, biotin carrier protein RPA3175 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 39934451 Common - possible glyoxalase RPA1377 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 39936177 Common - SEC-C motif RPA3114 88 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 39937415 Common pth peptidyl-tRNA hydrolase RPA4355 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 39935905 Common pimt2 putative D-aspartate protein carboxylmethyltransferase type II RPA2838 162 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 39937822 Common - Metallo-phosphoesterase:Tat pathway signal RPA4764 9 None None None 39934502 Common - possible lipoprotein RPA1428 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 39935653 Common lipA2 lipoyl synthase RPA2587 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 39934227 Nonpathogen - hypothetical protein RPA1152 6 None None None 39937400 Common ligE putative lignin beta-ether hydrolase RPA4340 24 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39935560 Nonpathogen - hypothetical protein RPA2494 2 None None None 39934139 Common - hypothetical protein RPA1064 15 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 39935862 Common - hypothetical protein RPA2795 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 39935145 Common - putative signal transduction histidine kinase RPA2076 29 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39937492 Common - NHL repeat RPA4432 29 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 39937377 Common - putative fosmidomycin resistance protein RPA4317 112 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39937816 Common - hypothetical protein RPA4758 32 None None None 39934803 Common fdxA putative ferredoxin RPA1733 15 COG1141 Fer, Ferredoxin Energy production and conversion 39936645 Common - hypothetical protein RPA3583 21 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 39935457 Common - acyl-CoA synthetase RPA2388 201 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39933539 Common - enoyl-CoA hydratase RPA0462 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39937559 Common - phnA-like protein RPA4501 104 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 39934936 Common - putative penicillin-binding protein RPA1867 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 39936400 Common - hypothetical protein RPA3337 2 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 39935130 Common nosZ nitrous-oxide reductase RPA2061 41 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 39935951 Common pyrG CTP synthetase RPA2886 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 39937073 Common - putative ATP-binding component of ABC transporter RPA4013 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 39935516 Common rne putative ribonuclease E RPA2450 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 39934519 Common - putative oligopeptide transport ATP-binding protein RPA1445 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 39937792 Common - hypothetical protein RPA4734 30 COG1434 COG1434, Uncharacterized conserved protein Function unknown 39934816 Common - hypothetical protein RPA1747 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 39936298 Common rplF 50S ribosomal protein L6 RPA3235 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 39937514 Common - Antifreeze protein, type I:5-formyltetrahydrofolate cyclo-ligase RPA4454 180 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 39933128 Common - hypothetical protein RPA0048 36 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 39936665 Common - possible transglycosylase RPA3603 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 39935711 Common - putative ABC transporter permease protein RPA2645 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39937203 Common nnrR putative nitric oxide responsive transcriptional regulator NnrR, Crp/Fnr family RPA4143 174 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39933355 Common - putative N-succinyldiaminopimelate aminotransferase RPA0278 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 39936922 Nonpathogen - hypothetical protein RPA3861 1 None None None 39933481 Common phhB pterin-4-alpha-carbinolamine dehydratase RPA0404 110 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 39934526 Nonpathogen - hypothetical protein RPA1452 1 None None None 39933281 Common cycW putative heme exporter protein B (heme ABC transporter membrane protein), cytochrome c biogenesis RPA0204 82 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 39936508 Common - probable acetyl-CoA synthetase RPA3445 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 39933361 Common - hypothetical protein RPA0284 47 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 39935648 Common - hypothetical protein RPA2582 24 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 39935706 Common - Isochorismatase hydrolase family RPA2640 65 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 39933566 Common - ferredoxin II RPA0489 160 COG1146 COG1146, Ferredoxin Energy production and conversion 39936841 Common - hypothetical protein RPA3780 5 None None None 39935498 Common - putative signal transduction histidine kinase with response regulator receiver domain RPA2432 223 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39934479 Common - putative urea amidolyase RPA1405 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 39936379 Common - possible chemotaxis cheB/cheR fusion protein RPA3316 157 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 39937827 Common opgC putative opgC protein RPA4769 36 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 39934424 Common exbB2 putative transport protein ExbB2 RPA1350 30 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39937528 Common - hypothetical protein RPA4468 28 COG3258 COG3258, Cytochrome c Energy production and conversion 39933182 Common oppA putative ABC transporter oligopeptide-binding protein RPA0102 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39935577 Common - possible membrane-bound lytic transglycosylase RPA2511 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 39933630 Common - hypothetical protein RPA0553 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 39935570 Common HDH homoserine dehydrogenase RPA2504 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 39935158 Common cobI precorrin 2 methylase RPA2089 166 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 39934055 Common - sensor histidine kinase with a PAS domain RPA0980 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39933681 Common lysC aspartate kinase RPA0604 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 39933422 Common - putative protoporphyrin IX magnesium chelatase bchO RPA0345 83 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39934194 Common TolA putative TolA RPA1119 11 COG5373 COG5373, Predicted membrane protein Function unknown 39934393 Common - hypothetical protein RPA1320 23 COG5207 UBP14, Isopeptidase T Posttranslational modification, protein turnover, chaperones 39934822 Common - hypothetical protein RPA1753 78 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 39937434 Common - putative protease RPA4374 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 39937050 Common - putative lipopolysaccharide-heptosyl-transferase RPA3989 80 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 39935288 Nonpathogen - Possible ATPase RPA2219 7 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 39936784 Common - possible leucine/isoleucine/valine-binding protein precursor RPA3723 66 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39936815 Common - Transglutaminase-like domain RPA3754 80 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 39935757 Common - DUF88 RPA2691 62 COG1432 COG1432, Uncharacterized conserved protein Function unknown 39937036 Nonpathogen - hypothetical protein RPA3975 1 None None None 39934690 Nonpathogen - hypothetical protein RPA1620 1 None None None 39933165 Nonpathogen - hypothetical protein RPA0085 9 None None None 39934389 Common - response regulator receiver (CheY-like protein) RPA1314 180 COG4566 TtrR, Response regulator Signal transduction mechanisms 39937392 Common gstA1 possible glutathione S-transferase RPA4332 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39936137 Common fabG2 3-oxoacyl-acyl carrier protein reductase fabG RPA3074 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935697 Common - possible ABC transport substrate-binding periplasmic protein RPA2631 44 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39937319 Common nuoG2 NADH dehydrogenase subunit G RPA4259 183 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 39936977 Common - TPR repeat RPA3916 152 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 39934900 Common - hypothetical protein RPA1831 30 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 39936354 Common - possible membrane transport protein RPA3291 89 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 39933429 Common lepA GTP-binding protein LepA RPA0352 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 39934447 Common vnfE putative nitrogenase cofactor synthesis protein RPA1373 53 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39937399 Common - enoyl-CoA hydratase RPA4339 184 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39937714 Common - possible sugar kinase RPA4656 151 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 39934686 Common - hypothetical protein RPA1616 14 None None None 39935378 Common - putative iron chelatin ABC transporter, permease subunit RPA2309 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 39936485 Common - possible transcriptional regulator, MarR family RPA3422 11 COG1846 MarR, Transcriptional regulators Transcription 39933526 Common - possible hydrolase/phosphatase RPA0449 132 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 39936666 Common - hypothetical protein RPA3604 55 COG2862 COG2862, Predicted membrane protein Function unknown 39935012 Common panE 2-dehydropantoate 2-reductase RPA1943 98 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 39935491 Common - putative lipase/esterase RPA2425 140 COG0657 Aes, Esterase/lipase Lipid metabolism 39935977 Common - possible (3R)-hydroxymyristoyl-acyl carrier protein dehydratase RPA2912 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 39935990 Nonpathogen - hypothetical protein RPA2925 3 None None None 39933416 Common dapB dihydrodipicolinate reductase RPA0339 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 39933201 Common - possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA RPA0124 75 COG1409 Icc, Predicted phosphohydrolases General function prediction only 39934205 Common glcD glycolate oxidase subunit GlcD RPA1130 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 39936130 Common - putative NAD-dependent alcohol dehydrogenase RPA3067 195 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 39937323 Common nuoB2 NADH-ubiquinone dehydrogenase chain B RPA4263 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 39935097 Nonpathogen - hypothetical protein RPA2028 1 None None None 39933448 Common metB putative cystathionine gamma-lyase RPA0371 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 39934848 Common - hypothetical protein RPA1779 18 None None None 39935523 Common - hypothetical protein RPA2457 35 None None None 39936118 Common - Integral membrane protein TerC family RPA3055 50 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 39936615 Common - arsenite efflux pump ACR3 RPA3553 125 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 39935565 Common - possible ABC transporter, periplasmic protein RPA2499 71 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39934377 Nonpathogen - hypothetical protein RPA1302 1 None None None 39935281 Common - hypothetical protein RPA2212 9 None None None 39936340 Common exbD putative exbD, uptake of enterochelin; tonB-dependent uptake of B colicins RPA3277 67 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 39937280 Common - ErfK/YbiS/YcfS/YnhG RPA4220 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39936285 Common - DUF24, predicted transcriptional regulator, related to MarR family RPA3222 149 COG1733 COG1733, Predicted transcriptional regulators Transcription 39934960 Nonpathogen - hypothetical protein RPA1891 2 None None None 39934382 Common - putative phosphatidylethanolamine-N-methyltransferase RPA1307 183 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39934176 Common - hypothetical protein RPA1101 33 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 39935118 Common dctM1 TrapT family, dctM subunit, C4-dicarboxylate transport RPA2049 133 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 39935940 Common - 7-cyano-7-deazaguanine reductase RPA2875 129 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 39935025 Common - hypothetical protein RPA1956 29 COG0433 COG0433, Predicted ATPase General function prediction only 39934481 Common - hypothetical protein RPA1407 52 COG3665 COG3665, Uncharacterized conserved protein Function unknown 39935949 Nonpathogen - hypothetical protein RPA2884 3 COG4104 COG4104, Uncharacterized conserved protein Function unknown 39936755 Common - putative cytochrome c RPA3693 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 39933396 Nonpathogen - hypothetical protein RPA0319 1 None None None 39935750 Common - hypothetical protein RPA2684 67 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 39934607 Common cycA cytochrome c2 RPA1535 52 COG3474 COG3474, Cytochrome c2 Energy production and conversion 39937053 Common - Fumarylacetoacetate (FAA) hydrolase RPA3992 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 39937031 Common - putative phosphatidylethanolamine-N-methyltransferase RPA3970 153 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39936267 Common - hypothetical protein RPA3204 13 None None None 39936656 Common - hypothetical protein RPA3594 20 COG5552 COG5552, Uncharacterized conserved protein Function unknown 39937156 Common - possible multidrug efflux membrane fusion protein mexE RPA4096 120 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39935485 Common - possible outer membrane protein, possible porin RPA2419 17 None None None 39933688 Common - hypothetical protein RPA0611 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 39936365 Common - hypothetical protein RPA3302 29 COG2030 MaoC, Acyl dehydratase Lipid metabolism 39936778 Common pimF enoyl-CoA hydratase RPA3717 183 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 39937407 Nonpathogen - hypothetical protein RPA4347 1 None None None 39934181 Common - hypothetical protein RPA1106 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 39935294 Common trbG1 probable conjugal transfer protein trbG RPA2225 51 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 39936771 Common - possible hemoprotein RPA3709 72 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 39937799 Common lysA diaminopimelate decarboxylase RPA4741 219 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 39935958 Common - putative cation-transporting ATPase RPA2893 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 39936682 Common vanR transcriptional regulator VanR, GntR family RPA3620 106 COG1802 GntR, Transcriptional regulators Transcription 39936622 Common - DUF81 RPA3560 9 COG0730 COG0730, Predicted permeases General function prediction only 39933605 Nonpathogen - hypothetical protein RPA0528 1 None None None 39937115 Common - hypothetical protein RPA4055 5 COG2246 COG2246, Predicted membrane protein Function unknown 39934637 Common - putative branched-chain amino acid transport system ATP-binding protein RPA1567 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39935343 Nonpathogen - hypothetical protein RPA2274 1 None None None 39936038 Nonpathogen - hypothetical protein RPA2973 3 None None None 39934757 Common - putative aldehyde dehydrogenase RPA1687 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39936425 Nonpathogen - hypothetical protein RPA3362 2 None None None 39936891 Common - possible G/U mismatch-specific DNA glycosylase RPA3830 27 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 39933384 Common - hypothetical protein RPA0307 11 None None None 39934075 Common - Nitrogenase-associated protein:Arsenate reductase and related RPA1000 20 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 39935539 Common - possible translation initiation inhibitor RPA2473 48 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 39936443 Common - response regulator receiver (CheY-like protein) RPA3380 222 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 39933497 Common - hypothetical protein RPA0420 37 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 39935822 Common - possible DNA-binding stress protein RPA2755 122 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 39934283 Common - putative dioxygenase RPA1208 35 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 39936337 Common nusG transcription antitermination protein NusG RPA3274 216 COG0250 NusG, Transcription antiterminator Transcription 39935545 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA2479 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39936002 Common nuoN1 NADH dehydrogenase subunit N RPA2937 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 39936095 Common - Phenylacetic acid degradation-related protein RPA3032 94 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39936660 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA3598 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39936637 Common thiG thiazole synthase RPA3575 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 39934645 Common - hypothetical protein RPA1575 53 COG3762 COG3762, Predicted membrane protein Function unknown 39935293 Common trbI1 possible trbI, a component on a type IV secretion system (Y10832) RPA2224 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 39937417 Common - hypothetical protein RPA4357 38 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 39937470 Common glpD glycerol-3-phosphate dehydrogenase RPA4410 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 39933910 Common coxE protoheme IX farnesyltransferase RPA0833 170 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 39933318 Common rplS 50S ribosomal protein L19 RPA0241 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 39935746 Common - hypothetical protein RPA2680 31 COG0657 Aes, Esterase/lipase Lipid metabolism 39933208 Common - ABC sulfate transport system, ATP-binding protein RPA0131 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39934679 Common mdlC benzoylformate decarboxylase RPA1609 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 161610776 Common clpS ATP-dependent Clp protease adaptor RPA1203 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 39937578 Common - NUDIX hydrolase RPA4520 82 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 39936604 Common emrB1 putative multidrug resistance protein B (drug efflux transporter) RPA3542 204 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39935210 Common - hypothetical protein RPA2141 62 COG3246 COG3246, Uncharacterized conserved protein Function unknown 39936696 Common tal bifunctional transaldolase/phosoglucose isomerase RPA3634 211 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 39937694 Nonpathogen - FeoA family RPA4636 6 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 39935406 Common - hypothetical protein RPA2337 6 None None None 39934001 Common - possible cyclopropane-fatty-acyl-phospholipid synthase RPA0924 123 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 39933779 Common phnM2 possible phosphonate ABC transporter, permease component RPA0702 55 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 39935401 Common - Rare lipoprotein A:Staphylococcus nuclease (SNase-like) RPA2332 103 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 39936359 Common - possible ABC transporter subunit (U75364) RPA3296 112 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39934041 Common hupE putative membrane-bound hydrogenase component hupE RPA0966 41 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 39933758 Common - membrane permeases, predicted cation efflux pump RPA0681 119 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39936566 Common - Thioesterase superfamily RPA3504 33 COG0824 FcbC, Predicted thioesterase General function prediction only 39935301 Common trbC1 putative conjugal transfer protein; TrbC RPA2232 22 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 39933622 Common - hypothetical protein RPA0545 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 39937659 Common - hypothetical protein RPA4601 18 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 39936827 Common paaC phenylacetic acid degradation protein paaC RPA3766 42 COG3396 COG3396, Uncharacterized conserved protein Function unknown 39934083 Common - probable transcriptional regulator, AraC family RPA1008 75 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39934699 Common cheY2 chemotaxis response regulator, CheY2 RPA1629 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39936307 Common rpsC 30S ribosomal protein S3 RPA3244 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 39937877 Nonpathogen - hypothetical protein RPA4819 1 None None None 39935463 Common - DUF208 RPA2396 66 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 39933927 Common - hypothetical protein RPA0850 138 COG0432 COG0432, Uncharacterized conserved protein Function unknown 39936948 Common flgC flagellar basal body rod protein FlgC RPA3887 125 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 39935247 Common - possible competence damage protein RPA2178 160 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 39933455 Common melA putative alpha-D-galactoside galactohydrolase RPA0378 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 39934160 Nonpathogen - hypothetical protein RPA1085 1 None None None 39934881 Nonpathogen - hypothetical protein RPA1812 1 None None None 39935609 Common - TrapT family, dctP subunit, C4-dicarboxylate periplasmic binding protein RPA2543 90 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 39934434 Nonpathogen - hypothetical protein RPA1360 2 None None None 39934589 Nonpathogen crtC hydroxyneurosporene dehydrogenase RPA1517 12 None None None 39933464 Common map putative methionine aminopeptidase RPA0387 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 39934151 Common - putative oxidoreductase RPA1076 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 39935380 Common - hypothetical protein RPA2311 4 None None None 39937477 Common - sensor histidine kinase with PAS/PAC and response regulator receiver domains RPA4417 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39935389 Common - possible TctA subunit of the Tripartite Tricarboxylate Transport(TTT) Family RPA2320 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 39933984 Common - response regulator receiver (CheY-like protein) RPA0907 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39934188 Common - probable transcriptional regulator, TetR family RPA1113 68 COG1309 AcrR, Transcriptional regulator Transcription 39936970 Common flgI flagellar basal body P-ring protein RPA3909 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 39933836 Common - putative oligopeptide ABC transporter, permease component RPA0759 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39935473 Common draG dinitrogenase reductase activating glycohydrolase RPA2406 68 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 39933719 Nonpathogen - hypothetical protein RPA0642 4 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 39936454 Common gch1 possible GTP cyclohydrolase I RPA3391 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 39933313 Common - hypothetical protein RPA0236 48 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 39934874 Common - transcriptional regulator, LysR family RPA1805 86 COG0583 LysR, Transcriptional regulator Transcription 39935368 Common - possible two-component transcriptional regulator, LuxR family RPA2299 108 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 39933751 Common - possible alcohol dehydrogenase class III family RPA0674 212 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 39936723 Common - Metal dependent phosphohydrolase RPA3661 186 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 39937286 Common - putative signal transduction histidine kinase with Chase domain RPA4226 29 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39936399 Common - possible lipopeptide antibiotics iturin a biosynthesis protein RPA3336 60 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 39934670 Common - BolA-like protein RPA1600 85 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 39933410 Common dnaK molecular chaperone DnaK RPA0333 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 39937448 Common - GCN5-related N-acetyltransferase RPA4388 82 COG3153 COG3153, Predicted acetyltransferase General function prediction only 39935805 Common - hypothetical protein RPA2738 23 COG5452 COG5452, Uncharacterized conserved protein Function unknown 39937735 Common - Caspase-1, p20:TPR repeat RPA4677 71 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 39934657 Nonpathogen - hypothetical protein RPA1587 1 None None None 39933435 Common chvI two-component transcriptional regulator ChvI, winged helix family RPA0358 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39935202 Common - hypothetical protein RPA2133 14 COG3904 COG3904, Predicted periplasmic protein Function unknown 39935395 Common - hypothetical protein RPA2326 205 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39936145 Common cfa2 cyclopropane-fatty-acyl-phospholipid synthase RPA3082 143 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 39937349 Common - putative dual use protein Tyr:Ser/Thr phosphatase RPA4289 33 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 39935151 Common cobA uroporphyrin-III C-methyltransferase RPA2082 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 39933937 Common - ABC transporter, periplasmic binding protein RPA0860 165 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 39934578 Common bchI putative Mg chelatase subunit Bchl RPA1506 85 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 39937544 Common - putative sensor (PAS) domain for methyl-accepting chemotaxis sensory transducer RPA4484 91 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 39935209 Common - probable transcriptional regulator, AraC family RPA2140 20 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39937637 Common - possible serine protease, htrA-like RPA4579 175 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39937274 Nonpathogen - hypothetical protein RPA4214 4 None None None 39933918 Common - putative ribosomal-protein-alanine N-acetyltransferase RPA0841 116 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 39936761 Common - possible iron-chelator utilization protein RPA3699 41 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 39934340 Common fliG flagellar motor switch protein G RPA1265 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 39937217 Common - possible asmA protein, assembly of outer membrane proteins RPA4157 49 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 39933838 Common - possible oligopeptide ABC transporter, periplasmic binding protein component RPA0761 182 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39934370 Common - putative signal transduction histidine kinase RPA1295 99 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39936067 Common kdpC potassium-transporting atpase c chain, KdpC RPA3002 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 39934214 Nonpathogen - hypothetical protein RPA1139 3 None None None 39933214 Common cheB1 chemotaxis methylesterase, CheB1 RPA0137 214 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 39936852 Common - probable transcriptional regulator, TetR family RPA3791 87 COG1309 AcrR, Transcriptional regulator Transcription 39936835 Common - possible D-amino-acid dehydrogenase RPA3774 137 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 39936691 Nonpathogen - hypothetical protein RPA3629 4 None None None 39937454 Common aceA isocitrate lyase RPA4394 114 COG2224 AceA, Isocitrate lyase Energy production and conversion 39936039 Common - putative 6-aminohexanoate-cyclic-dimer hydrolase RPA2974 216 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 161610774 Common - putative portal protein, R. capsulatus GTA orfg3 homologue RPA1885 58 COG4695 COG4695, Phage-related protein Function unknown 39937381 Common paaG3 putative enoyl-CoA hydratase paaG RPA4321 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39934171 Common - methyl-accepting chemotaxis sensory transducer RPA1096 137 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 161610769 Common msrA1 methionine sulfoxide reductase A RPA4070 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 39935235 Common - hypothetical protein RPA2166 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 39935035 Common - probable transcriptional regulator, TetR family RPA1966 116 COG1309 AcrR, Transcriptional regulator Transcription 39933308 Common - hypothetical protein RPA0231 55 COG2862 COG2862, Predicted membrane protein Function unknown 39937342 Common - possible activator of photopigment and puc with BLUF domain RPA4282 42 None None None 39934992 Common amiF formamidase RPA1923 110 COG0388 COG0388, Predicted amidohydrolase General function prediction only 39933725 Common flgK1 possible flagellar hook-associated protein 1 (HAP1, FlgK protein) RPA0648 56 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 39935623 Common - Glycosyl transferase, family 2 RPA2557 157 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39935311 Common - hypothetical protein RPA2242 13 None None None 39935929 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 RPA2864 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 39933168 Nonpathogen - hypothetical protein RPA0088 3 None None None 39937464 Common - putative periplasmic binding ABC transporter protein, probable sugar binding RPA4404 34 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 39935304 Common traG2 plasmid transfer factor, traG protein RPA2235 77 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 39936223 Common - DUF218 RPA3160 96 COG1434 COG1434, Uncharacterized conserved protein Function unknown 39933576 Common - DedA family RPA0499 69 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 39936496 Common - possible salicylate hydroxylase RPA3433 55 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 39935898 Common secD preprotein translocase subunit SecD RPA2831 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 39935687 Common - hypothetical protein RPA2621 27 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 39934766 Common - hypothetical protein RPA1696 46 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 39937882 Common - hypothetical protein RPA4824 8 None None None 39935557 Common argC N-acetyl-gamma-glutamyl-phosphate reductase RPA2491 213 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 39933575 Common cobS2 cobS protein RPA0498 70 COG0714 COG0714, MoxR-like ATPases General function prediction only 39935619 Common - hypothetical protein RPA2553 79 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 39936190 Common - NUDIX hydrolase RPA3127 23 None None None 39935264 Common - possible exopolyphosphatase RPA2195 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 39935854 Common - putative signal transduction histidine kinase with PAS/PAC domain RPA2787 102 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39935020 Common - possible FusE-MFP/HlyD family membrane fusion protein RPA1951 120 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39934390 Common - two-component transcriptional regulator, LuxR family RPA1315 215 COG4566 TtrR, Response regulator Signal transduction mechanisms 39933158 Common - hypothetical protein RPA0078 196 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 39934925 Common - hypothetical protein RPA1856 98 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 39934869 Common - Elongator protein 3/MiaB/NifB RPA1800 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 39936386 Nonpathogen - hypothetical protein RPA3323 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 39933510 Common rpsO 30S ribosomal protein S15 RPA0433 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 39935527 Common anmK anhydro-N-acetylmuramic acid kinase RPA2461 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 39936673 Common - ErfK/YbiS/YcfS/YnhG RPA3611 82 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39935188 Common - putative permease protein of ABC transporter RPA2119 183 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 39935305 Common - hypothetical protein RPA2236 27 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 39936657 Common - hypothetical protein RPA3595 25 None None None 39937626 Common - enoyl-(acyl carrier protein) reductase RPA4568 228 COG0623 FabI, Enoyl- acyl-carrier-protein 39933136 Common ugpE sn-glycerol 3-phosphate transport system, integral membrane protein RPA0056 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 39936719 Common fadD2 acyl-CoA synthetase RPA3657 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936389 Common - hypothetical protein RPA3326 2 None None None 39935196 Common exbB3 putative exbB, uptake of enterochelin; tonB-dependent uptake of B colicins RPA2127 126 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39935558 Common - hypothetical protein RPA2492 70 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 39935818 Common - possible transferase RPA2751 81 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39935192 Common - hypothetical protein RPA2123 86 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 39933801 Common nxiA putative high-affinity nickel-transport protein RPA0724 37 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 39937660 Common fixX ferredoxin like protein, fixX RPA4602 35 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 39935338 Common - hypothetical protein RPA2269 72 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 39936235 Common - transcriptional regulator, LysR family RPA3172 92 COG0583 LysR, Transcriptional regulator Transcription 39936524 Common - Thiolase RPA3462 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39937628 Nonpathogen - hypothetical protein RPA4570 8 None None None 39935088 Common - 3-oxoacyl-(acyl carrier protein) synthase II RPA2019 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936377 Common degP putative DegP protease precursor RPA3314 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39935310 Common - hypothetical protein RPA2241 18 COG5419 COG5419, Uncharacterized conserved protein Function unknown 39933118 Common rplT 50S ribosomal protein L20 RPA0038 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 39934013 Common - possible transcriptional regulator, TetR family RPA0936 34 COG1309 AcrR, Transcriptional regulator Transcription 39936724 Common ureB urease subunit beta RPA3662 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 39936322 Common - hypothetical protein RPA3259 34 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39936792 Common - Alpha/beta hydrolase fold:Esterase/lipase/thioesterase, active site RPA3731 123 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39934828 Common - Tyrosine protein kinase:Aminoglycoside phosphotransferase RPA1759 59 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 39933258 Common priA primosome assembly protein PriA RPA0181 210 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 39935147 Nonpathogen - hypothetical protein RPA2078 1 None None None 39936700 Common - thermoresistant gluconokinase RPA3638 83 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 39937189 Common - possible transcriptional regulator, XRE family RPA4129 36 COG1396 HipB, Predicted transcriptional regulators Transcription 39937042 Common - hypothetical protein RPA3981 36 COG0392 COG0392, Predicted integral membrane protein Function unknown 39934299 Common iorA putative indolepyruvate ferredoxin oxidoreductase, alpha subunit RPA1224 106 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 39936408 Nonpathogen - hypothetical protein RPA3345 7 None None None 39937371 Common - methyl-accepting chemotaxis sensory transducer RPA4311 159 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39935811 Nonpathogen - hypothetical protein RPA2744 1 None None None 39936176 Common - hypothetical protein RPA3113 152 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 39936438 Nonpathogen - hypothetical protein RPA3375 1 None None None 39936189 Common - hypothetical protein RPA3126 27 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 39934226 Common - hypothetical protein RPA1151 99 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 39937531 Common - hypothetical protein RPA4471 17 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 39935136 Common - hypothetical protein RPA2067 18 COG5615 COG5615, Predicted integral membrane protein Function unknown 39933476 Common - possible transposase RPA0399 96 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 39937890 Common clcD putative dienelactone hydrolase RPA4832 110 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 39935317 Common - hypothetical protein RPA2248 43 None None None 39933941 Nonpathogen - hypothetical protein RPA0864 2 None None None 39933177 Common - putative flagellar basal-body rod protein flgC RPA0097 78 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 39937378 Common mrsA phosphoglucomutase/phosphomannomutase family protein MrsA RPA4318 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 39935845 Common - possible deoxyribonuclease RPA2778 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 39935878 Common mazG nucleoside triphosphate pyrophosphohydrolase RPA2811 155 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 39937449 Common - Small Conductance Mechanosensitive (MscS) Ion Channel RPA4389 75 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 39937056 Nonpathogen - hypothetical protein RPA3995 2 None None None 39936698 Common zwf glucose-6-phosphate 1-dehydrogenase RPA3636 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 39937396 Common - putative oxidoreductase RPA4336 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 39934851 Common - TrapT family, dctP subunit, C4-dicarboxylate periplasmic binding protein RPA1782 78 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 39936315 Common tufA elongation factor Tu RPA3252 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 39933971 Common - putative transposase RPA0894 51 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 39937098 Common - possible ABC transport system ATP-binding protein RPA4038 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39937452 Nonpathogen - hypothetical protein RPA4392 4 None None None 39933652 Common - putative intracellular PHB depolymerase RPA0575 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 39934573 Common - possible coenzyme F420 hydrogenase beta subunit RPA1501 37 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 39937848 Common - response regulator receiver:histidine kinase RPA4790 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 39937809 Common - DUF80 RPA4751 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 39936250 Common - sensor histidine kinase with a PAS/PAC domain RPA3187 210 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39933087 Common - putative signal transduction histidine kinase with PAS/PAC domains RPA0007 55 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39937602 Nonpathogen - hypothetical protein RPA4544 2 None None None 39935331 Common gltS putative glutamate permease RPA2262 51 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 39933154 Common - Possible exonuclease V and helicase activity based on COG assignment RPA0074 200 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 39937428 Common - two-component transcriptional regulator, winged helix family RPA4368 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39933290 Common - possible OmpA family member RPA0213 76 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 39935441 Common mexA putative RND multidrug efflux membrane fusion protein MexA precursor RPA2371 140 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39935930 Nonpathogen - hypothetical protein RPA2865 4 None None None 39936071 Nonpathogen - hypothetical protein RPA3006 1 None None None 39936808 Common eutC ethanolamine ammonia-lyase small subunit RPA3747 52 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 39933695 Nonpathogen - hypothetical protein RPA0618 2 None None None 39933432 Common - PTS system permease (IIAMan), nitrogen regulatory IIA protein RPA0355 94 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 39935438 Common - pseudogene-two-component transcriptional regulator, winged helix family RPA2369 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39933930 Common - sensor histidine kinase, possible proline sensor PrlS RPA0853 218 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 39937538 Nonpathogen - hypothetical protein RPA4478 1 None None None 39933544 Common - glycerate dehydrogenase RPA0467 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 39933603 Common rpmF 50S ribosomal protein L32 RPA0526 91 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 39934996 Nonpathogen - hypothetical protein RPA1927 7 COG1633 COG1633, Uncharacterized conserved protein Function unknown 39937726 Common coxM carbon monoxide dehydrogenase chain C RPA4668 91 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 39936831 Nonpathogen - hypothetical protein RPA3770 6 COG5490 COG5490, Uncharacterized conserved protein Function unknown 39935159 Common cobH precorrin-8X methylmutase RPA2090 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 39934169 Common - glutaryl-CoA dehydrogenase RPA1094 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39935871 Common - hypothetical protein RPA2804 6 None None None 39933133 Common - hypothetical protein RPA0053 14 COG5568 COG5568, Uncharacterized small protein Function unknown 39936710 Nonpathogen - hypothetical protein RPA3648 7 None None None 39935081 Common - hypothetical protein RPA2012 86 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 39933439 Common penP putative class A beta-lactamase precursor (penicillinase) RPA0362 65 COG2367 PenP, Beta-lactamase class A Defense mechanisms 39934611 Nonpathogen bchF possible 2-vinyl bacteriochlorophillide hydratase BchF subunit (AB034704) RPA1541 14 None None None 39935110 Common - ABC-transport protein, ATP-binding protein RPA2041 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39935165 Common cobQ2 cobyric acid synthase RPA2096 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 39934933 Nonpathogen - hypothetical protein RPA1864 4 None None None 39937271 Common glsA glutaminase RPA4211 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 39933959 Common - ABC transporter, permease RPA0882 155 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39934254 Common - beta alanine--pyruvate transaminase RPA1179 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 39937321 Common nuoE2 NADH dehydrogenase subunit E RPA4261 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 39935117 Common dctQ1 possible TrapT family, dctQ subunit, C4-dicarboxylate transport RPA2048 56 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 39937697 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4639 142 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39934553 Common - response regulator receiver (CheY-like protein) RPA1481 63 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39935393 Common gabD2 succinate-semialdehyde dehydrogenase RPA2324 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39934596 Common bchZ bacteriochlorophyllide reductase subunit RPA1524 32 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39935667 Common coaD phosphopantetheine adenylyltransferase RPA2601 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 39934374 Common - hypothetical protein RPA1299 32 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 39934955 Nonpathogen - hypothetical protein RPA1886 3 None None None 39935412 Common - transcriptional regulator, GntR family RPA2343 93 COG1802 GntR, Transcriptional regulators Transcription 39934540 Common - hypothetical protein RPA1468 23 None None None 39936898 Common - possible insertion element ISR1 RPA3837 58 None None None 39935615 Nonpathogen - hypothetical protein RPA2549 2 COG3610 COG3610, Uncharacterized conserved protein Function unknown 39933112 Nonpathogen - possible Staphylococcal nuclease homologues RPA0032 6 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 39934909 Common folP dihydropteroate synthase RPA1840 216 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 39936413 Common - putative aminotransferase RPA3350 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 39934498 Common - possible selenocysteine lyase RPA1424 241 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 39934769 Common - putative acyl-CoA dehydrogenase RPA1699 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39935169 Common - possible hydrolase RPA2100 77 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 39934121 Common - hypothetical protein RPA1046 44 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 39935342 Nonpathogen - hypothetical protein RPA2273 2 None None None 39934302 Common oorB 2-oxoglutarate ferredoxin oxidoreductase subunit beta RPA1227 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 39935433 Common - possible nitrogenase iron-molybdenum cofactor biosynthesis protein NifE homolog RPA2364 63 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39937689 Common fer1 ferredoxin 2[4Fe-4S], fdxN RPA4631 104 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 39937669 Common nifQ putative nitrogen fixation protein nifQ RPA4611 23 None None None 39933946 Common - GCN5-related N-acetyltransferase RPA0869 72 COG3153 COG3153, Predicted acetyltransferase General function prediction only 39934243 Common moaE molybdopterin converting factor, subunit 2 RPA1168 139 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 39934862 Common - branched-chain amino acid transport system permease protein RPA1793 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39936373 Common katE catalase RPA3310 125 COG0753 KatE, Catalase Inorganic ion transport and metabolism 39935747 Common - hypothetical protein RPA2681 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 39936126 Common - organic solvent tolerance protein homolog RPA3063 114 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 39934876 Common - possible heavy metal efflux pump, HlyD family secretion protein RPA1807 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39936430 Common - possible activator of photopigment and puc with BLUF domain RPA3367 43 None None None 39937136 Common - transcriptional regulator, LysR family RPA4076 188 COG0583 LysR, Transcriptional regulator Transcription 39934563 Nonpathogen pucBe light harvesting protein B-800-850, beta chain E (antenna pigment protein, beta chain E) (LH II-E beta) RPA1491 7 None None None 39935533 Common sufS sufS, putative selenosysteine lyase RPA2467 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 39937597 Nonpathogen - hypothetical protein RPA4539 1 None None None 39937440 Common - Ribonuclease T2 RPA4380 46 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 39937757 Common FldX possible dehydrogenase RPA4699 19 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 39936624 Common arsM arsenite S-adenosylmethyltransferase RPA3562 201 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39934057 Common pcaR putativetranscriptional regulator PcaR, IclR family RPA0982 120 COG1414 IclR, Transcriptional regulator Transcription 39936960 Common flgF flagellar basal body rod protein FlgF RPA3899 120 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 39935032 Common - Patatin-like phospholipase domain RPA1963 11 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 39937571 Common - putative signal transduction histidine kinase RPA4513 40 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39933845 Common - possible transposase RPA0768 45 None None None 39934748 Common cheR3 chemotaxis methyltransferase, CheR3 RPA1678 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 39933847 Common - Integrase, catalytic domain RPA0770 126 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 39933993 Nonpathogen - hypothetical protein RPA0916 8 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 39936923 Nonpathogen - hypothetical protein RPA3862 1 None None None 39935122 Nonpathogen - hypothetical protein RPA2053 3 None None None 39936834 Nonpathogen - hypothetical protein RPA3773 14 None None None 39935458 Common - possible Rhizobactin siderophore biosynthesis protein RhsF RPA2389 50 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 39937855 Common - ABC transporter, amino acid binding protein RPA4797 106 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 39937264 Nonpathogen - hypothetical protein RPA4204 1 None None None 39936951 Common fliP flagellar biosynthesis protein FliP RPA3890 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 39934211 Common ictP putative L-lactate permease RPA1136 103 COG1620 LldP, L-lactate permease Energy production and conversion 39937883 Common - transcriptional regulator, MerR family RPA4825 121 COG0789 SoxR, Predicted transcriptional regulators Transcription 39934730 Common - putative cation transporting P-type ATPase RPA1660 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 39936268 Common - Type III secretion proteins, related to flagellar biosynthesis protein FlhB RPA3205 118 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 39933268 Common sucC succinyl-CoA synthetase subunit beta RPA0191 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 39933798 Common cobC putative cobalamin biosynthetic protein CobC RPA0721 188 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 39935909 Common - SCP-like extracellular protein RPA2844 21 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 39934685 Common - putative methyltransferase RPA1615 197 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39936940 Common - hypothetical protein RPA3879 54 COG3791 COG3791, Uncharacterized conserved protein Function unknown 39935015 Common - possible transcriptional regulator, GntR family RPA1946 127 COG1802 GntR, Transcriptional regulators Transcription 39934009 Common - hypothetical protein RPA0932 15 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 39934004 Common - transcriptional regulator, XRE family RPA0927 53 COG3655 COG3655, Predicted transcriptional regulator Transcription 39935323 Nonpathogen - hypothetical protein RPA2254 2 None None None 39937811 Common - histidine kinase with a response regulator receiver domain RPA4753 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39933203 Common - possible sugar binding protein of ABC transporter RPA0126 96 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 39933744 Common hbaF putative membrane spanning subunit of ABC transporter RPA0667 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39934715 Nonpathogen - hypothetical protein RPA1645 1 None None None 39934218 Common - possible Major Facilitator Family (MFS) transporter RPA1143 42 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 39935392 Common goaT 4-aminobutyrate aminotransferase RPA2323 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 39933702 Common - hypothetical protein RPA0625 23 COG3152 COG3152, Predicted membrane protein Function unknown 39937017 Common - ferredoxin RPA3956 54 COG0633 Fdx, Ferredoxin Energy production and conversion 39935779 Common hemB delta-aminolevulinic acid dehydratase RPA2712 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 39935788 Nonpathogen - hypothetical protein RPA2721 1 None None None 39937358 Common - ATP/GTP-binding site motif A (P-loop) RPA4298 104 COG2606 EbsC, Uncharacterized conserved protein Function unknown 39936395 Nonpathogen - hypothetical protein RPA3332 1 None None None 39937593 Nonpathogen - hypothetical protein RPA4535 1 None None None 39933496 Common - possible short chain dehydrogenase/reductase family member RPA0419 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 39937681 Common fixU hypothetical protein RPA4623 20 COG5554 NifU, Nitrogen fixation protein Secondary metabolites biosynthesis, transport, and catabolism 39934264 Nonpathogen - hypothetical protein RPA1189 3 COG5475 COG5475, Uncharacterized small protein Function unknown 39935225 Nonpathogen - hypothetical protein RPA2156 5 None None None 39935774 Common - possible fusaric acid resistance pump RPA2708 52 COG1289 COG1289, Predicted membrane protein Function unknown 39935970 Common glnS glutaminyl-tRNA synthetase RPA2905 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 39933220 Common cheY1 response regulator receiver, CheY1 RPA0143 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39937167 Common oprN putative outer membrane efflux protein OprN precursor RPA4107 114 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39936550 Common - probable serine protease RPA3488 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 39936275 Nonpathogen - hypothetical protein RPA3212 1 None None None 39936539 Common exbD5 exbD, uptake of enterochelin; tonB-dependent uptake of B colicins RPA3477 134 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 39934914 Common - putative tonB-dependent receptor protein RPA1845 78 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 39936930 Common - transcriptional regulator, XRE family RPA3869 31 COG1396 HipB, Predicted transcriptional regulators Transcription 39934798 Common - hypothetical protein RPA1728 10 None None None 39937257 Common rpmJ 50S ribosomal protein L36 RPA4197 54 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 39937124 Nonpathogen - hypothetical protein RPA4064 1 None None None 39934321 Nonpathogen - hypothetical protein RPA1246 6 None None None 39936261 Common - hypothetical protein RPA3198 25 COG3752 COG3752, Predicted membrane protein Function unknown 39934276 Common aroC chorismate synthase RPA1201 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 39936904 Common kefC putative potassium efflux transporter RPA3843 212 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 39936064 Common ptsN2 putative nitrogen regulatory IIA protein RPA2999 128 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 39936163 Common - hypothetical protein RPA3100 68 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 39937312 Common nuoN2 NADH-ubiquinone dehydrogenase chain N RPA4252 185 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 39936442 Nonpathogen - hypothetical protein RPA3379 1 None None None 39937194 Common - transcriptional regulatorf, XRE family RPA4134 20 None None None 39935914 Common tatA twin argininte translocase protein A RPA2849 95 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 39937064 Nonpathogen - hypothetical protein RPA4003 2 None None None 39934664 Common trpB-1 tryptophan synthase subunit beta RPA1594 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 39934023 Common - hypothetical protein RPA0946 10 None None None 39936903 Common - Uncharacterized iron-regulated membrane protein DUF337 RPA3842 20 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 39936606 Common - transcriptional regulator, TetR family RPA3544 128 COG1309 AcrR, Transcriptional regulator Transcription 39934388 Common - sensor histidine kinase with multiple PAS/PAC domains RPA1313 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 39937158 Common - putative RNA polymerase ECF-type sigma factor RPA4098 5 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39937328 Common - peroxiredoxin-like protein RPA4268 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 39936391 Nonpathogen - possible transcriptional regulator, XRE family RPA3328 1 None None None 39937795 Nonpathogen - hypothetical protein RPA4737 15 None None None 39935983 Common uppS undecaprenyl pyrophosphate synthetase RPA2918 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 39937196 Common - possible DNA topoisomerase RPA4136 245 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 39934359 Common - hypothetical protein RPA1284 46 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 39935046 Common - possible TrapT family, dctQ subunit, glutamate transport RPA1977 69 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 39933082 Common dnaN DNA polymerase III subunit beta RPA0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 39935749 Common dur1 DUF213 RPA2683 109 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 39933163 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase RPA0083 207 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39935728 Common recG ATP-dependent DNA helicase RPA2662 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 39937251 Common - hypothetical protein RPA4191 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 39933232 Common - putative tolR/exbD protein RPA0155 139 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 39936976 Common - flagellin RPA3915 115 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 39936598 Common - putative penicillin-binding protein RPA3536 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 39936043 Nonpathogen - hypothetical protein RPA2978 1 None None None 39936180 Common pyrB aspartate carbamoyltransferase catalytic subunit RPA3117 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 39935076 Common pssA possible phosphatidylserine synthase RPA2007 147 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 39934095 Common - possible membrane fusion protein precursor; predicted cation efflux pumps RPA1020 100 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39933714 Nonpathogen - hypothetical protein RPA0637 3 None None None 39936527 Common - putative long-chain-fatty-acid CoA ligase RPA3465 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934303 Common - putative 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit RPA1228 52 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 39933705 Common - hypothetical protein RPA0628 7 COG5480 COG5480, Predicted integral membrane protein Function unknown 39934764 Common ccrB camphor resistance protein CrcB RPA1694 154 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 39937769 Nonpathogen - hypothetical protein RPA4711 3 None None None 39936571 Common - permease, ABC-2-type transport system RPA3509 154 COG1511 COG1511, Predicted membrane protein Function unknown 39934496 Nonpathogen - hypothetical protein RPA1422 8 None None None 39935520 Common - putative dehydrogenase RPA2454 165 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 39935053 Common aroG2 2-dehydro-3-deoxyphosphoheptonate aldolase RPA1984 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 39937160 Nonpathogen - hypothetical protein RPA4100 2 None None None 39936308 Common rplV 50S ribosomal protein L22 RPA3245 214 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 39935364 Nonpathogen - hypothetical protein RPA2295 2 COG3212 COG3212, Predicted membrane protein Function unknown 39936004 Common nuoL1 NADH dehydrogenase subunit L RPA2939 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 39937708 Common potA putative spermidine/putrescine transport system ATP-binding protein RPA4650 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 39933921 Common atpF2 putative FoF1 ATP synthase, subunit B' RPA0844 35 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 39935735 Common - hypothetical protein RPA2669 42 COG3785 COG3785, Uncharacterized conserved protein Function unknown 39935062 Common - possible virulence-associated protein RPA1993 20 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 39935694 Common aapJ-2 polar amino acid ABC transport substrate-binding protein, aapJ-2 RPA2628 131 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 39934588 Nonpathogen - hypothetical protein RPA1516 2 None None None 39936054 Common - putative quinone oxidoreductase RPA2989 189 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39934237 Common garS phosphoribosylamine--glycine ligase RPA1162 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 39935472 Nonpathogen draT2 NAD+ ADP-ribosyltransferase RPA2405 11 None None None 39935580 Common - putative lysyl-tRNA synthetase RPA2514 201 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 39936198 Common dinP DNA polymerase IV RPA3135 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 39936585 Common ftsA putative cell division protein FtsA RPA3523 176 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 39936971 Nonpathogen - chemotactic signal-response protein CheL RPA3910 11 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 39934411 Common - hypothetical protein RPA1337 11 None None None 39937749 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4691 64 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39933805 Common - hypothetical protein RPA0728 6 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39934721 Common - possible leucine/isoleucine/valine-binding protein precursor RPA1651 115 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39937221 Nonpathogen - hypothetical protein RPA4161 6 COG1378 COG1378, Predicted transcriptional regulators Transcription 39934101 Common - possible adenine DNA methyltransferase RPA1026 142 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 39935002 Common glnE putative glutamate-ammonia-ligase adenylyltransferase RPA1933 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 39936575 Common - phytoene dehydrogenase-related protein RPA3513 74 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39936206 Common - hypothetical protein RPA3143 10 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 39936861 Common - hypothetical protein RPA3800 49 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 39933250 Common - putative sugar nucleotide dehydratase RPA0173 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39936462 Common cspA4 cold shock DNA binding protein RPA3399 176 COG1278 CspC, Cold shock proteins Transcription 39934115 Common - octaprenyl-diphosphate synthase RPA1040 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 39936259 Nonpathogen - hypothetical protein RPA3196 3 None None None 39936580 Common - Excinuclease ABC, C subunit, N-terminal RPA3518 42 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 39935263 Common - possible carbon-monoxide dehydrogenase large subunit RPA2194 107 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 39933632 Common - possible methyltransferase RPA0555 111 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39933976 Common - putative transglycolase RPA0899 100 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 39936744 Common - hypothetical protein RPA3682 80 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 39936027 Common tig trigger factor RPA2962 208 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 39937740 Common - possible RND efflux membrane fusion protein precursor RPA4682 52 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39937295 Nonpathogen - putative cytochrome c, class I RPA4235 9 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 39934978 Common - transcriptional regulator, MarR family RPA1909 53 COG1846 MarR, Transcriptional regulators Transcription 39936968 Common dksA DnaK suppressor protein DksA RPA3907 160 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 39933626 Common ChrR sensor protein ChrR, cytochrome cycA regulator RPA0549 28 COG3806 ChrR, Transcriptional activator Transcription 39933736 Common badF benzoyl-CoA reductase subunit RPA0659 63 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 39935924 Common - hypothetical protein RPA2859 4 None None None 39936124 Common - possible permease RPA3061 52 COG0795 COG0795, Predicted permeases General function prediction only 39934282 Common - PAS domain:sigma-54-dependent transcriptional regulator, Fis family RPA1207 176 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 39937432 Common - hypothetical protein RPA4372 98 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 39933596 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase RPA0519 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 39933724 Nonpathogen - hypothetical protein RPA0647 2 None None None 39937552 Common apt adenine phosphoribosyltransferase RPA4492 196 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 39935585 Nonpathogen - hypothetical protein RPA2519 1 None None None 39937139 Nonpathogen - hypothetical protein RPA4079 5 None None None 39933519 Common trmB tRNA (guanine-N(7))-methyltransferase RPA0442 170 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 39933814 Common - putative oxalate/formate Major Facilitator Superfamily (MFS) antiporter RPA0737 80 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 39934351 Common carA carbamoyl phosphate synthase small subunit RPA1276 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 39937543 Common - methyl-accepting chemotaxis sensory transducer RPA4483 138 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39933791 Common cobU bifunctional cobinamide kinase, cobinamide phosphate guanylyltransferase protein RPA0714 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 39935596 Nonpathogen - hypothetical protein RPA2530 1 None None None 39936973 Nonpathogen - hypothetical protein RPA3912 3 None None None 39937754 Common FldA hypothetical protein RPA4696 56 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 39933674 Common - possible competence protein F (COMF) RPA0597 162 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 39933757 Common - possible transcriptional regulator, TetR family RPA0680 19 COG1309 AcrR, Transcriptional regulator Transcription 39935718 Nonpathogen - hypothetical protein RPA2652 2 None None None 39934834 Common - enoyl-CoA hydratase RPA1765 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39934710 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA1640 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39933857 Common - possible acyl-CoA dehydrogenase RPA0780 140 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39933818 Common - hypothetical protein RPA0741 97 COG0714 COG0714, MoxR-like ATPases General function prediction only 39933524 Common - possible phoH-like protein RPA0447 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 39935366 Common - flagellin RPA2297 84 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 39933550 Common PA3602 possible glutamate synthase. RPA0473 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 39936854 Common - hypothetical protein RPA3793 15 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 39935502 Common accB putative biotin carboxyl carrier protein of acetyl-CoA carboxylase RPA2436 192 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 39936473 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS domains RPA3410 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39934341 Nonpathogen fliH flagellar assembly protein H RPA1266 9 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 39935429 Common - ABC transporter, ATP-binding protein RPA2360 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 39935603 Common - possible NADH dehydrogenase (ubiquinone) Fe-S protein 4 (18kD) (NADH-coenzyme Q reductase) RPA2537 37 None None None 39937781 Common polA DNA polymerase I RPA4723 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 39935827 Common - possible benzaldehyde lyase RPA2760 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39934760 Common - hypothetical protein RPA1690 24 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 39935689 Common - possible sulfonate transport system permease protein. Subunit of an ABC transporter RPA2623 173 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39934888 Common - RNA polymerase sigma factor RPA1819 163 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39937888 Common - Metal dependent phosphohydrolase with a response regulator receiver domain RPA4830 92 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 39935992 Common - possible ABC type permease; lipoprotein releasing factor RPA2927 165 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 39937401 Common - Beta-lactamase-like RPA4341 43 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 39933907 Common - hypothetical protein RPA0830 14 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 39936426 Nonpathogen - hypothetical protein RPA3363 1 None None None 39933508 Common - methyl-accepting chemotaxis receptor/sensory transducer with PAS domain RPA0431 159 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39934166 Common - hypothetical protein RPA1091 39 None None None 39934682 Common - putative acyl-CoA dehydrogenase RPA1612 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39933995 Common rpmE 50S ribosomal protein L31 RPA0918 129 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 39934407 Common - hypothetical protein RPA1333 11 None None None 39936348 Common - putative dehydrogenase RPA3285 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936487 Nonpathogen - hypothetical protein RPA3424 2 None None None 39936143 Common rplI 50S ribosomal protein L9 RPA3080 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 39936293 Common secY preprotein translocase subunit SecY RPA3230 235 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 39936763 Common metF putative 5,10-methylenetetrahydrofolate reductase RPA3701 141 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 39935030 Common - RND efflux transporter RPA1961 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39934655 Common - putative hemmolysin III, HlyIII family RPA1585 118 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 39935237 Common - putative H+/nucleoside symporter RPA2168 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 39937145 Common - transcriptional regulator, TetR family RPA4085 40 COG1309 AcrR, Transcriptional regulator Transcription 39934207 Common glcF glycolate oxidase subunit, (Fe-S)protein, GlcF RPA1132 175 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 39933912 Common coxG cytochrome C oxidase assembly protein RPA0835 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 39937419 Common - DUF185 RPA4359 92 COG1565 COG1565, Uncharacterized conserved protein Function unknown 39933098 Common ccoO cytochrome-c oxidase fixO chain RPA0018 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 39937486 Common - Glutathione S-transferase, N-terminal RPA4426 72 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 39933121 Common - hypothetical protein RPA0041 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39935116 Common dctP1 TrapT family, dctP subunit, C4-dicarboxylate periplasmic binding protein RPA2047 109 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 39934586 Common hemF coproporphyrinogen III oxidase RPA1514 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 39935203 Nonpathogen - hypothetical protein RPA2134 1 None None None 39933237 Common - possible acetyltransferase RPA0160 120 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 39937575 Nonpathogen - hypothetical protein RPA4517 2 None None None 39933530 Common - possible NifU-like domain (residues 119-187) RPA0453 96 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 39936741 Common - possible pilus assembly protein cpaD RPA3679 14 COG5461 COG5461, Type IV pili component Cell motility and secretion 39933573 Common cobT2 cobT protein RPA0496 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 39937348 Common - hypothetical protein RPA4288 3 None None None 39934315 Common exbD1 biopolymer transport protein ExbD RPA1240 134 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 39935179 Common - probable transcriptional regulator, AraC family RPA2110 145 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39936654 Nonpathogen - hypothetical protein RPA3592 1 None None None 39933628 Common - transcriptional regulator, LysR family RPA0551 190 COG0583 LysR, Transcriptional regulator Transcription 39936996 Nonpathogen - hypothetical protein RPA3935 2 None None None 39934048 Common hypA hydrogenase formation/expression protein hypA RPA0973 81 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 39933122 Common - possible iron-sulfur cluster binding protein RPA0042 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 39934131 Common - putative dehydrogenase (zinc-binding alcohol dehydrogenase, NADPH quinone oxidoreductase, oxidoreductase) RPA1056 119 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 39937568 Common - hypothetical protein RPA4510 84 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 39936560 Common - possible chromate transport protein similar to chrA RPA3498 69 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 39936687 Common - Excinuclease ABC, C subunit, N-terminal RPA3625 17 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 39934335 Common - Universal stress protein (Usp) RPA1260 89 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 39934086 Common - DSBA oxidoreductase RPA1011 13 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 39935552 Common parE DNA topoisomerase IV subunit B RPA2486 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 39935856 Common phaA putative monovalent cation/H+ antiporter subunit A RPA2789 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 39935742 Common - transcriptional regulator, LysR family RPA2676 192 COG0583 LysR, Transcriptional regulator Transcription 39934040 Common hupD hydrogenase maturation protein hupD RPA0965 81 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 39937244 Nonpathogen - hypothetical protein RPA4184 1 None None None 39935670 Common - peptidyl prolyl cis-trans isomerase RPA2604 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 39934197 Common - hypothetical protein RPA1122 8 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 39933488 Common ppa inorganic pyrophosphatase RPA0411 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 39934132 Nonpathogen - hypothetical protein RPA1057 5 None None None 39937113 Common - possible dTDPglucose 4,6-dehydratase RPA4053 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39935703 Common - possible nitrogenase iron-molybdenum protein subunit nifK homolog RPA2637 63 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39933452 Common chaB putative cation transport regulator RPA0375 19 COG4572 ChaB, Putative cation transport regulator General function prediction only 39935830 Common - O-acetylhomoserine aminocarboxypropyltransferase RPA2763 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 39934077 Common modD putative molybdenum transport system protein RPA1002 116 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 39934989 Common cycJ cytochrome c-type biogenesis protein CcmE RPA1920 97 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 39937818 Nonpathogen - hypothetical protein RPA4760 1 None None None 39934453 Nonpathogen vnfG vanadium dinitrogenase delta subunit RPA1379 5 None None None 39937084 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase RPA4024 48 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 39937699 Common cbbM ribulose-bisphosphate carboxylase form II RPA4641 65 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 39935939 Common eno enolase RPA2874 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 39935968 Common lexA LexA repressor RPA2903 166 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 39937260 Common - YbaK / prolyl-tRNA synthetase associated domain RPA4200 69 COG2606 EbsC, Uncharacterized conserved protein Function unknown 39936339 Common - possible tonB protein RPA3276 22 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 39933793 Common cobN cobaltochelatase RPA0716 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 39937658 Common - hypothetical protein RPA4600 20 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 39936226 Common mgtE putative magnesium transporter RPA3163 169 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 39937292 Nonpathogen - hypothetical protein RPA4232 2 None None None 39935997 Nonpathogen - hypothetical protein RPA2932 2 None None None 39937666 Common nifS2 nitrogenase cofactor synthesis protein nifS RPA4608 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 39934696 Common - hypothetical protein RPA1626 29 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 39937879 Common - 5'-methylthioadenosine phosphorylase RPA4821 137 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 39936032 Common glnA glutamine synthetase I RPA2967 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 39933932 Common - Beta-lactamase-like RPA0855 98 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39933215 Common cheR1 chemotaxis methyltransferase, CheR1 RPA0138 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 39934697 Common cheA2 multidomain chemotaxis histidine kinase CheA2 (Hpt, CheA, CheW, & Resp. Reg. Rec. domains) RPA1627 212 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 39934530 Common norB nitric-oxide reductase subunit B RPA1456 122 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 39937648 Common - homoserine O-succinyltransferase RPA4590 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 39936303 Common rplN 50S ribosomal protein L14 RPA3240 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 39936270 Common - hypothetical protein RPA3207 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 39934789 Common - hypothetical protein RPA1719 21 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 39935231 Common - possible serine protease/outer membrane autotransporter RPA2162 79 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 39936494 Nonpathogen - hypothetical protein RPA3431 7 None None None 39935655 Common cinA possible competence-damaged protein RPA2589 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 39936216 Common - hypothetical protein RPA3153 6 COG2267 PldB, Lysophospholipase Lipid metabolism 39936567 Nonpathogen - hypothetical protein RPA3505 1 None None None 39937289 Nonpathogen - hypothetical protein RPA4229 1 None None None 39935275 Common - hypothetical protein RPA2206 7 None None None 39936822 Common - putative catechol 2,3-dioxygenase RPA3761 41 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 39937506 Nonpathogen - hypothetical protein RPA4446 2 COG5612 COG5612, Predicted integral membrane protein Function unknown 39935806 Common - hypothetical protein RPA2739 24 None None None 39933614 Common - coenzyme A transferase RPA0537 94 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 39934432 Common - hypothetical protein RPA1358 2 None None None 39934756 Common - putative alcohol dehydrogenase RPA1686 89 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 39936406 Common mtfB possible mannosyltransferase B RPA3343 114 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39936734 Common cspA5 cold shock DNA binding protein RPA3672 177 COG1278 CspC, Cold shock proteins Transcription 39933459 Common glgA1 putative glycogen synthase RPA0382 127 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 39937793 Nonpathogen - hypothetical protein RPA4735 1 None None None 39936999 Common - possible oxidoreductase RPA3938 103 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 39935256 Common - hypothetical protein RPA2187 140 COG2081 COG2081, Predicted flavoproteins General function prediction only 39937421 Common - hypothetical protein RPA4361 7 None None None 39936786 Common ilvJ possible leucine/isoleucine/valine-binding protein precursor RPA3725 102 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934420 Common - possible TonB protein, possible colicin J receptor RPA1346 61 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 39935404 Nonpathogen - hypothetical protein RPA2335 1 None None None 39935213 Common - possible biotin carboxylase RPA2144 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 39935846 Common - possible hydrolase RPA2779 79 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 39933230 Common - possible outer membrane receptor for Fe transport RPA0153 92 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39937174 Common - transcriptional regulator, LysR family RPA4114 189 COG0583 LysR, Transcriptional regulator Transcription 39937079 Common - putative branched-chain amino acid ABC transporter system substrate-binding protein RPA4019 150 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935465 Common - iron siderophore uptake receptor family, probable Mg/Co uptake RPA2398 91 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39937475 Common - putative component of multidrug efflux system RPA4415 156 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39935241 Common - putative oxidoreductase RPA2172 232 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 39937639 Common - hypothetical protein RPA4581 12 None None None 39934116 Common - hypothetical protein RPA1041 23 None None None 39935987 Common rpsB 30S ribosomal protein S2 RPA2922 221 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 39936758 Common - transcriptional regulator, TetR family RPA3696 51 COG1309 AcrR, Transcriptional regulator Transcription 39933637 Common MLYCD malonyl-CoA decarboxylase RPA0560 29 None None None 39937521 Common - possible cytochrome subunit of sulfide dehydrogenase RPA4461 37 COG2863 COG2863, Cytochrome c553 Energy production and conversion 39934437 Common - sulfate ester transport system permease protein RPA1363 180 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39933505 Common - hypothetical protein RPA0428 6 None None None 39934942 Common - possible urea/short-chain binding protein of ABC transporter RPA1873 76 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934348 Common - possible deoxyribonuclease RPA1273 102 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 39936411 Common - possible polysaccharide export protein RPA3348 83 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 39937561 Nonpathogen - hypothetical protein RPA4503 3 None None None 39933693 Common - Uncharacterized BCR RPA0616 178 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 39936040 Common serA1 putative phosphoglycerate dehydrogenase RPA2975 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 39936709 Common - putative glycosyl hydrolase RPA3647 109 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 39937200 Common - sensor histidine kinase with a PAS domain RPA4140 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39937102 Common - putative long-chain-fatty-acid--CoA ligase RPA4042 205 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 39935975 Common - hypothetical protein RPA2910 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 39933769 Common phnJ PhnJ protein, phosphonate metabolism, function unknown. RPA0692 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 39936139 Common - putative diguanylate cyclase (GGDEF) RPA3076 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39933923 Common atpB F0F1 ATP synthase subunit A RPA0846 201 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 39935709 Common - putative ABC transporter ATP-binding protein RPA2643 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 39935884 Common - hypothetical protein RPA2817 7 None None None 39933418 Common ogt possible Ada polyprotein (O6-methylguanine-DNA methyltransferase) RPA0341 204 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 39934902 Common - PilT protein, N-terminal RPA1833 14 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 39936817 Common - malate dehydrogenase-like protein RPA3756 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 39934179 Common ndh putative NADH dehydrogenase RPA1104 153 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 39937862 Nonpathogen - hypothetical protein RPA4804 1 None None None 39937184 Common trbB2 conjugal transfer protein trbB RPA4124 211 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 39937468 Common - ATP-binding protein of sugar ABC transporter RPA4408 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 39933295 Common sdhD succinate dehydrogenase cytochrome b small subunit RPA0218 35 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 39933434 Common exoS two component sensor histidine kinase RPA0357 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39934773 Common - acetyl-CoA acetyltransferase RPA1703 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39934811 Common yeaU putative tartrate dehydrogenase RPA1742 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 39936342 Common pigA possible iron-starvation protein RPA3279 9 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 39933350 Common amtB1 ammonium transporter AmtB RPA0273 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 39935861 Common phaG putative pH adaptation potassium efflux system component phaG RPA2794 32 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 39935563 Common - putative anion ABC transporter, ATP-binding protein RPA2497 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39935269 Common guaB inositol-5-monophosphate dehydrogenase RPA2200 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 39935333 Nonpathogen - hypothetical protein RPA2264 4 None None None 39934555 Common - NAD binding site:FAD dependent oxidoreductase RPA1483 64 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 39936233 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS and GAF domains RPA3170 190 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39937604 Common - hypothetical protein RPA4546 21 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 39937493 Common clpB endopeptidase Clp: ATP-binding subunit B, clpB RPA4433 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 39937273 Common - sulfite reductase hemoprotein subunit RPA4213 169 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 39935172 Common - hypothetical protein RPA2103 4 None None None 39936097 Nonpathogen - hypothetical protein RPA3034 3 None None None 39937239 Common - hypothetical protein RPA4179 54 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 39934818 Common - putative branched-chain amino acid transport system permease protein RPA1749 143 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39934385 Common - putative NADH:flavin oxidoreductase RPA1310 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 39934173 Nonpathogen - hypothetical protein RPA1098 1 None None None 39935942 Common - glucosyltransferase MdoH RPA2877 62 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 39937070 Common - response regulator receiver (CheY-like protein) RPA4010 118 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39936183 Common DprA DNA processing chain A RPA3120 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 39934183 Common - DGPF domain RPA1108 17 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 39933244 Common - DUF163 RPA0167 163 COG1576 COG1576, Uncharacterized conserved protein Function unknown 39936329 Common - possible pyridine nucleotide-disulphide oxidored RPA3266 7 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 39936132 Common gmk guanylate kinase RPA3069 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 39936369 Common nirK1 nitrite reductase, major outer membrane copper-containing protein RPA3306 48 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 39935632 Common - putative EA59 gene protein, phage lambda RPA2566 12 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 39937023 Common - ATP-binding component of ABC transporter RPA3962 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 39934974 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg13 (37% identity) RPA1905 29 COG5449 COG5449, Uncharacterized conserved protein Function unknown 39936886 Common - hypothetical protein RPA3825 55 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 39937282 Nonpathogen - hypothetical protein RPA4222 3 None None None 39936090 Common kup1 potassium uptake protein Kup RPA3027 90 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 39934158 Common - hypothetical protein RPA1083 4 None None None 39936445 Common - hypothetical protein RPA3382 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 39936311 Common rplW 50S ribosomal protein L23 RPA3248 229 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 39934920 Common - hypothetical protein RPA1851 106 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 39933339 Common rlp2 ribulose bisphosphate carboxylase-like protein; rubisco-like protein RPA0262 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 39937631 Nonpathogen - hypothetical protein RPA4573 4 None None None 39935717 Common - Endoribonuclease, protein synthesis inhibitor RPA2651 48 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 39937091 Nonpathogen - hypothetical protein RPA4031 2 None None None 39935824 Common - hypothetical protein RPA2757 14 None None None 39934805 Common bglA putative beta-glucosidase RPA1736 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 39934727 Common - putative diguanylate cyclase (GGDEF) RPA1657 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39933401 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase RPA0324 207 COG0313 COG0313, Predicted methyltransferases General function prediction only 39933840 Common - possible methyltransferase RPA0763 86 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 39935291 Common - transcriptional regulator, LysR family RPA2222 175 COG0583 LysR, Transcriptional regulator Transcription 39936591 Common murC UDP-N-acetylmuramate--L-alanine ligase RPA3529 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 39933274 Common - possible ABC transporter permeases RPA0197 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 39935961 Nonpathogen - hypothetical protein RPA2896 2 None None None 39936635 Common thiO thiamine biosynthesis oxidoreductase thiO RPA3573 88 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 39936546 Common - PilT protein, N-terminal RPA3484 25 COG5573 COG5573, Predicted nucleic-acid-binding protein, contains PIN domain General function prediction only 39936157 Common - putative tetracycline-efflux transporter RPA3094 109 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39937035 Common - putative dehydrogenase RPA3974 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 39933661 Common - transcriptional accessory protein RPA0584 145 COG2183 Tex, Transcriptional accessory protein Transcription 39934145 Nonpathogen - hypothetical protein RPA1070 2 None None None 39934520 Common - possible dipeptide ABC transporter (dipeptide-binding protein) RPA1446 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39934468 Common - transcriptional regulator, GntR family with aminotransferase domain RPA1394 207 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 39934532 Common norD dinitrification protein NorD RPA1458 50 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 39936647 Nonpathogen - hypothetical protein RPA3585 1 None None None 39934224 Common hisG ATP phosphoribosyltransferase RPA1149 123 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 39933263 Common - putative short-chain dehydrogenase/reductase RPA0186 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935410 Common ilvD putative dihydroxy-acid dehydratase RPA2341 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 39935109 Common - possible choline ABC transporter ATP-binding subunit RPA2040 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 39933547 Common - perplasmic binding protein of ABC transporter RPA0470 61 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39937820 Common ogt2 putative O-6-methylguanine-DNA methyltransferase RPA4762 205 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 39937857 Common - possible acyl-CoA dehydrogenase RPA4799 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39933196 Common rmlD putative dTDP-6-deoxy-L-mannose-dehydrogenase RPA0119 164 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 39933378 Common dnaQ putative DNA polymerase III epsilon chain RPA0301 195 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 39933885 Common - hypothetical protein RPA0808 34 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 39934461 Common - hypothetical protein RPA1387 26 COG2014 COG2014, Uncharacterized conserved protein Function unknown 39934720 Common - putative ABC transporter, ATP-binding protein RPA1650 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 39936663 Nonpathogen - hypothetical protein RPA3601 3 None None None 39934049 Common hypB hydrogenase expression/formation protein hypB RPA0974 104 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 39933364 Common leuS leucyl-tRNA synthetase RPA0287 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 39933773 Common - possible transcriptional regulator, GntR family RPA0696 80 COG2188 PhnF, Transcriptional regulators Transcription 39935167 Common - Glutamine amidotransferase class-I RPA2098 206 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 39934963 Nonpathogen - hypothetical protein RPA1894 2 None None None 39935095 Common - ferric siderophore receptor RPA2026 86 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39934474 Common - possible Glutamine amidotransferase RPA1400 179 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 39934949 Common - putative membrane transport protein-major facilitator superfamily RPA1880 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39935340 Common - pyruvate kinase RPA2271 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 39937119 Nonpathogen - hypothetical protein RPA4059 1 None None None 39934788 Nonpathogen - hypothetical protein RPA1718 4 None None None 39933446 Common - Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like RPA0369 45 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 39933332 Common gcp O-sialoglycoprotein endopeptidase RPA0255 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 39937825 Common - Lipolytic enzyme, G-D-S-L family RPA4767 12 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 39937215 Common - 3-oxoadipate CoA-transferase subunit B RPA4155 101 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 39934524 Common - putative pyruvate carboxylase RPA1450 232 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 39935492 Common - hypothetical protein RPA2426 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 39936479 Common - protein with 2 CBS domains RPA3416 132 COG0517 COG0517, FOG: CBS domain General function prediction only 39937226 Common - putative nitrilase RPA4166 71 COG0388 COG0388, Predicted amidohydrolase General function prediction only 39935646 Common - possible protein-L-isoaspartate O-methyltransferase RPA2580 151 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 39934426 Nonpathogen - hypothetical protein RPA1352 1 None None None 39936721 Common - DUF176 RPA3659 26 COG1359 COG1359, Uncharacterized conserved protein Function unknown 39935699 Common - putative ATP-binding protein of ABC transporter, possibly for nitrate RPA2633 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 39935470 Common - possible iron-chelator utilization protein RPA2403 55 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 39933856 Nonpathogen - hypothetical protein RPA0779 2 None None None 39937526 Common soxZ2 putative sulfur oxidation protein soxZ RPA4466 34 None None None 39936616 Common arsC2 arsenate reductase RPA3554 101 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 39933865 Common - possible Major Facilitator Superfamily (MFS) efflux pump RPA0788 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39937711 Common bisC biotin sulfoxide reductase RPA4653 160 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 39935467 Common - hypothetical protein RPA2400 21 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 39935371 Common - acyl-CoA synthetase RPA2302 217 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 39935479 Common - possible permease of ABC transporter RPA2412 135 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39936174 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C RPA3111 163 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 39936288 Common rplQ 50S ribosomal protein L17 RPA3225 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 39933420 Common nth endonuclease III DNA-(apurinic or apyrimidinic site) lyase RPA0343 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 39933283 Common cycY putative cytochrome c biogenesis protein, thiol:disulfide interchange protein RPA0206 154 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 39937394 Common - possible acyltransferase RPA4334 98 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 39935102 Common - possible AtsE RPA2033 13 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 39933191 Common - DUF81 RPA0111 22 COG0730 COG0730, Predicted permeases General function prediction only 39933873 Common - hypothetical protein RPA0796 46 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 39933408 Common - possible heat shock protein (HSP-70 COFACTOR), grpE RPA0331 226 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 39935753 Common mscL large-conductance mechanosensitive channel RPA2687 135 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 39936150 Nonpathogen - hypothetical protein RPA3087 5 None None None 39935593 Common - possible DNA-dependent RNA polymerase RPA2527 6 COG5108 RPO41, Mitochondrial DNA-directed RNA polymerase Transcription 39934395 Common - putative signal transduction histidine kinase RPA1322 83 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 39935575 Nonpathogen - hypothetical protein RPA2509 1 None None None 39933928 Common - possible MFS transporter RPA0851 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39934984 Common feuP two-component transcriptional regulator FeuP, winged helix family RPA1915 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39934613 Common bchB light-independent protochlorophyllide reductase subunit B RPA1543 52 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39935163 Common cobT1 putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase RPA2094 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 39937376 Common - hypothetical protein RPA4316 24 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 39933272 Common tesA putative acyl-CoA thioesterase precursor RPA0195 106 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 39934287 Nonpathogen - Alpha/beta hydrolase fold RPA1212 19 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39933739 Common badB ferredoxin RPA0662 103 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 39936994 Common - sensor histidine kinase with multiple PAS and a response regulator receiver domain RPA3933 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39937767 Common - hypothetical protein RPA4709 17 None None None 39933427 Common vsr putative patch repair protein RPA0350 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 39937209 Common - Beta-lactamase-like RPA4149 122 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 39934478 Common - amidase RPA1404 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39936712 Common ligD ATP-dependent DNA ligase RPA3650 80 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 39936878 Common purB adenylosuccinate lyase RPA3817 234 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 39933542 Common - possible transmembrane protein RPA0465 41 COG5361 COG5361, Uncharacterized conserved protein Function unknown 39937535 Common - hypothetical protein RPA4475 32 COG2391 COG2391, Predicted transporter component General function prediction only 39935799 Common - hypothetical protein RPA2732 13 COG3798 COG3798, Uncharacterized protein conserved in bacteria Function unknown 39936273 Common - possible prolyl oligopeptidase family Dienelactone hydrolase family RPA3210 18 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 39933852 Nonpathogen - hypothetical protein RPA0775 2 None None None 39937180 Common - possible conjugal transfer protein trbJ RPA4120 24 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 39937849 Common - two-component transcriptional regulator, winged helix family RPA4791 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 39933645 Common - probable hydrolase RPA0568 217 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 39933948 Nonpathogen - hypothetical protein RPA0871 3 None None None 39936020 Common mex possible RND efflux membrane fusion protein precursor RPA2955 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39935451 Common - putative iron(III) ABC transporter, ATP-binding protein RPA2382 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 39937565 Common - Elongator protein 3/MiaB/NifB RPA4507 75 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 39936035 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase RPA2970 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 39936056 Nonpathogen - hypothetical protein RPA2991 1 None None None 39936185 Common - hypothetical protein RPA3122 2 None None None 39933114 Common - possible flavin containing amine oxidase RPA0034 25 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 39935561 Common - possible translation initiation inhibitor RPA2495 66 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 39937224 Common - possible aliphatic sulfonate binding protein of ABC transporter system RPA4164 72 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39936088 Nonpathogen - hypothetical protein RPA3025 2 None None None 39935880 Nonpathogen - hypothetical protein RPA2813 1 None None None 39935272 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein RPA2203 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 39936371 Common - ycfI, putative structural proteins RPA3308 38 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 39934551 Common - putative transport system ATP-binding protein RPA1479 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 39936799 Common - transcriptional regulator, LysR family RPA3738 155 COG0583 LysR, Transcriptional regulator Transcription 39934127 Common - hypothetical protein RPA1052 41 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 39933297 Common czcD putative cation efflux system protein RPA0220 171 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 39933138 Common ugpB1 putative sn-glycerol 3-phosphate transport system; periplasmic binding protein RPA0058 89 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 39933135 Common ugpC ATP-binding component of sn-glycerol 3-phosphate transport system RPA0055 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 39934155 Common - possible 2-pyrone-4,6-dicarboxylate hydrolase RPA1080 44 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 39937545 Common mutY adenine glycosylase mutY RPA4485 217 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 39937005 Common - hypothetical protein RPA3944 56 COG0392 COG0392, Predicted integral membrane protein Function unknown 39933618 Common - hypothetical protein RPA0541 29 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 39934148 Common - possible ADP-RIBOSE PHOSPHOHYDROLASE RPA1073 184 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 39936552 Common hflC putative hflC protein RPA3490 213 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 39934280 Common - putative alcohol dehydrogenase RPA1205 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 39936626 Common tnaA tryptophanase RPA3564 44 COG3033 TnaA, Tryptophanase Amino acid transport and metabolism 39934976 Common - hypothetical protein RPA1907 53 COG3791 COG3791, Uncharacterized conserved protein Function unknown 39935351 Common - hypothetical protein RPA2282 52 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 39934754 Common - putative 3-ketoacyl-acyl carrier protein reductase RPA1684 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935610 Nonpathogen - hypothetical protein RPA2544 1 None None None 39935120 Common - putative ornithine decarboxylase RPA2051 85 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 39936415 Common - glycosyltransferase RPA3352 132 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39933166 Common moeB putative molybdenum cofactor biosynthesis protein RPA0086 214 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 39936984 Common - putative acetoin dehydrogenase (TPP-dependent) alpha chain RPA3923 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 39934923 Common - possible transcriptional regulator, TetR family RPA1854 83 COG1309 AcrR, Transcriptional regulator Transcription 39936675 Common - putative thiosulfate sulfurtransferase RPA3613 146 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 39937759 Common ligA Protocatechuate 4,5-dioxygenase, alpha chain RPA4701 15 None None None 39934289 Common - putative ABC transporter ATP-binding protein RPA1214 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 39933170 Nonpathogen - hypothetical protein RPA0090 1 None None None 39934032 Common - putative 5`-nucleotidase family protein RPA0955 137 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 39934565 Common pucC PucC, possible chlorophyll Major Facilitator Superfamily (MFS) exporter RPA1493 23 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39933569 Common - hypothetical protein RPA0492 15 None None None 39934635 Common - putative urea/short-chain amide transport system permease protein RPA1565 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39935812 Common - possible ferric siderophore receptor protein RPA2745 82 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39935531 Common sufC sufC, related to ABC transporter ATP-binding protein RPA2465 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 39936078 Common - two-component transcriptional regulator, LuxR family RPA3014 204 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 39937674 Common nifN nitrogenase reductase-associated ferredoxin, nifN RPA4616 48 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39933156 Common - Nucleotidyl transferase RPA0076 209 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 39933975 Common dapA dihydrodipicolinate synthase RPA0898 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 39935419 Common metC putative O-acetylhomoserine sulfhydrylase RPA2350 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 39936806 Nonpathogen - hypothetical protein RPA3745 4 None None None 39936914 Nonpathogen - hypothetical protein RPA3853 3 None None None 39935889 Nonpathogen - hypothetical protein RPA2822 2 None None None 39935897 Common secF preprotein translocase subunit SecF RPA2830 209 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 39935049 Common cbbZ phosphoglycolate phosphatase RPA1980 155 COG0546 Gph, Predicted phosphatases General function prediction only 39937302 Common - hypothetical protein RPA4242 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 39937621 Common exoI2 Staphylococcus nuclease (SNase-like) RPA4563 24 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 39933179 Common oppD putative oligopeptide ABC transporter (ATP-binding protein) RPA0099 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 39936639 Common thiC thiamine biosynthesis protein ThiC RPA3577 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 39935525 Common - putative permease RPA2459 86 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39935308 Common - putative partition protein RPA2239 202 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 39934491 Common - putative branched-chain amino acid transport system ATP-binding protein RPA1417 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39933961 Common - ABC transporter, substrate-binding protein RPA0884 47 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39936375 Common - Transglutaminase-like domain RPA3312 77 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 39936966 Common - possible transcriptional regulator, TetR family RPA3905 17 COG1309 AcrR, Transcriptional regulator Transcription 39936559 Common - possible Chromate transporter related to ChrA RPA3497 54 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 39936727 Common - possible ATP-binding component of ABC transporter RPA3665 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936929 Common - putatively similar to frnE protein RPA3868 80 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 39935907 Common - hypothetical protein RPA2840 3 COG2320 GrpB, Uncharacterized conserved protein Function unknown 39934356 Common - hypothetical protein RPA1281 22 COG3832 COG3832, Uncharacterized conserved protein Function unknown 39936531 Common - probable permease protein of sugar ABC transporter RPA3469 177 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 39933093 Common rdxI putative cation (heavy metal) transporting ATPase RPA0013 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 39933304 Common leuB 3-isopropylmalate dehydrogenase RPA0227 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 39935933 Common - Septum formation initiator RPA2868 9 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 39936921 Nonpathogen - hypothetical protein RPA3860 1 None None None 39937802 Common - possible thioredoxin-like protein RPA4744 136 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 39937370 Nonpathogen - hypothetical protein RPA4310 2 COG4907 COG4907, Predicted membrane protein Function unknown 39937764 Common - DedA family RPA4706 51 COG1238 COG1238, Predicted membrane protein Function unknown 39934843 Common - OmpA/MotB domain, possible porin RPA1774 161 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 39933341 Common - possible O-antigen acetylase RPA0264 101 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 39936790 Common - hippurate hydrolase RPA3729 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 39935227 Nonpathogen - hypothetical protein RPA2158 5 None None None 39936029 Common - Multicopper oxidase, type 1 RPA2964 26 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 39933186 Common - possible branched-chain amino acid transport system substrate-binding protein RPA0106 89 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935902 Common - hypothetical protein RPA2835 16 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 39934558 Common - hypothetical protein RPA1486 58 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 39936330 Common rpoC DNA-directed RNA polymerase subunit beta' RPA3267 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 39933586 Common - hypothetical protein RPA0509 54 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 39937398 Common - transcriptional regulator, TetR family RPA4338 85 COG1309 AcrR, Transcriptional regulator Transcription 39937447 Common - possible ferrichrome-iron receptor RPA4387 50 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39933478 Common - NAD binding site:Amine oxidase RPA0401 80 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39934704 Common - hypothetical protein RPA1634 16 None None None 39934033 Nonpathogen - hypothetical protein RPA0956 4 None None None 39934784 Common - hypothetical protein RPA1714 6 None None None 39935399 Common - putative ABC transporter ATP-binding protein RPA2330 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 39937187 Common - hypothetical protein RPA4127 14 None None None 39933808 Common - transcriptional regulator, LysR family RPA0731 178 COG0583 LysR, Transcriptional regulator Transcription 39934449 Nonpathogen - hypothetical protein RPA1375 1 None None None 39934514 Nonpathogen - hypothetical protein RPA1440 7 None None None 39934883 Nonpathogen - hypothetical protein RPA1814 3 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 39936252 Common - NUDIX hydrolase RPA3189 44 None None None 39934957 Common - putative major capsid protein, R. capsulatus GTA orfg5 homologue RPA1888 52 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 39933227 Common - putative ABC transporter, iron, hemin permease homolog RPA0150 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 39937836 Common pstA phosphate transport system permease protein PstA RPA4778 222 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 39935149 Common - zinc-containing dehydrogenase RPA2080 207 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 39936436 Nonpathogen - hypothetical protein RPA3373 1 None None None 39934175 Common ruvA Holliday junction DNA helicase motor protein RPA1100 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 39936194 Common - hypothetical protein RPA3131 34 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 39933726 Nonpathogen flgL flagellar hook-associated protein FlgL RPA0649 10 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 39937892 Common msrA2 methionine sulfoxide reductase A RPA4834 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 39933690 Common - NUDIX hydrolase RPA0613 105 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 39934371 Common - putative diguanylate cyclase (GGDEF) with HAMP domain RPA1296 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39933697 Common - Uncharacterized BCR:Protein of unknown function DUF195 RPA0620 123 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 39935424 Common - possible nitrogenase NifB RPA2355 22 COG1433 COG1433, Uncharacterized conserved protein Function unknown 39933256 Common atpH F0F1 ATP synthase subunit delta RPA0179 188 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 39933152 Common folC putative folylpolyglutamate synthase / dihydrofolate synthase RPA0072 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 39934965 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg6 (21% idenity) RPA1896 18 None None None 39935768 Common - DUF24, predicted transcriptional regulator, related to MarR family RPA2702 143 COG1733 COG1733, Predicted transcriptional regulators Transcription 39936011 Nonpathogen - hypothetical protein RPA2946 2 None None None 39935574 Common recJ putative single-strand DNA-specific exonuclease RPA2508 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 39935985 Common pyrH uridylate kinase RPA2920 246 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 39933707 Nonpathogen - DUF423 RPA0630 3 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 39937151 Common - transcriptional regulator, TetR family RPA4091 11 COG1309 AcrR, Transcriptional regulator Transcription 39937797 Common - hypothetical protein RPA4739 28 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 39936207 Nonpathogen - hypothetical protein RPA3144 5 None None None 39937309 Common - response regulator receiver (CheY-like protein) RPA4249 205 COG4566 TtrR, Response regulator Signal transduction mechanisms 39933871 Common acaP a-type carbonic anhydrase RPA0794 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 39934762 Common - putative transmembrane transport protein RPA1692 88 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39933812 Common fdsC formate dehydrogenase accessory protein RPA0735 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 39935994 Common - hypothetical protein RPA2929 19 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 39934305 Common - putative ABC transporter, permease protein RPA1230 157 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39933987 Common - DUF209:Cupin domain RPA0910 147 COG1741 COG1741, Pirin-related protein General function prediction only 39934050 Common hypF hydrogenase maturation protein hypF RPA0975 113 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 39936249 Nonpathogen - hypothetical protein RPA3186 3 None None None 39936006 Common nuoJ1 NADH dehydrogenase subunit J RPA2941 148 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 39934103 Common moaB molybdopterin biosynthesis, protein B RPA1028 121 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 39934128 Common nadC nicotinate-mononucleotide pyrophosphorylase RPA1053 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 39937619 Common - guanosine 5'-monophosphate oxidoreductase RPA4561 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 39936504 Common - enoyl-CoA hydratase RPA3441 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936958 Common fliM flagellar motor switch protein FliM RPA3897 110 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 39936689 Common - putative glutathione peroxidase RPA3627 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 39936257 Common - acetyl-CoA acetyltransferase RPA3194 91 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39933658 Common - hypothetical protein RPA0581 27 COG3759 COG3759, Predicted membrane protein Function unknown 39934060 Common - putative branched-chain amino acid transport system substrate-binding protein RPA0985 101 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935004 Common - possible transcriptional regulator, AraC family RPA1935 46 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39933104 Common - short chain dehydrogenase RPA0024 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39935261 Nonpathogen - hypothetical protein RPA2192 2 None None None 39934864 Common - possible potassium-efflux system protein RPA1795 205 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 39933491 Common - hypothetical protein RPA0414 37 COG1872 COG1872, Uncharacterized conserved protein Function unknown 39933521 Common lnt apolipoprotein N-acyltransferase RPA0444 162 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 39934791 Common - transcriptional regulator, LysR family RPA1721 125 COG0583 LysR, Transcriptional regulator Transcription 39934137 Common - hypothetical protein RPA1062 19 COG5373 COG5373, Predicted membrane protein Function unknown 39933843 Common - transcriptional regulator, Crp/Fnr family RPA0766 161 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39936122 Common - DNA polymerase III subunit chi RPA3059 44 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 39934853 Common - TrapT family, dctM subunit, C4-dicarboxylate transport RPA1784 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 39937352 Nonpathogen pucAb light harvesting protein B-800-850, alpha chain B (antenna pigment protein, alpha chain B) (LH II-B alpha) RPA4292 1 None None None 39935617 Nonpathogen - hypothetical protein RPA2551 7 None None None 39933878 Common - hypothetical protein RPA0801 15 None None None 39935598 Nonpathogen - hypothetical protein RPA2532 1 None None None 39933348 Common tesB acyl-CoA thioesterase II RPA0271 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 39933734 Common badD benzoyl-CoA reductase subunit RPA0657 29 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 39937240 Common pntB nicotinamide nucleotide transhydrogenase, subunit beta RPA4180 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 39933151 Common accD acetyl-CoA carboxylase subunit beta RPA0071 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 39935354 Common prfC peptide chain release factor 3 RPA2285 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 39937359 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA4299 143 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 39934580 Common - hypothetical protein RPA1508 12 None None None 39937550 Common - hypothetical protein RPA4490 17 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 39936519 Nonpathogen - Biotin/lipoyl attachment:Biotin-requiring enzyme, attachment site RPA3457 3 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 39933676 Common - possible nitrilase RPA0599 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 39933553 Nonpathogen - hypothetical protein RPA0476 10 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39934404 Common - hypothetical protein RPA1330 52 COG2966 COG2966, Uncharacterized conserved protein Function unknown 39933624 Common - hypothetical protein RPA0547 30 COG0400 COG0400, Predicted esterase General function prediction only 39934759 Common - hypothetical protein RPA1689 14 None None None 39934080 Common - NUDIX hydrolase RPA1005 36 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 39934113 Common - TPR repeat RPA1038 135 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 39936283 Common - recombination factor protein RarA RPA3220 222 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 39936404 Common - putative acetyltransferase RPA3341 28 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 39936880 Nonpathogen - hypothetical protein RPA3819 2 None None None 39933598 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) RPA0521 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39936548 Common - putative branched-chain amino acid transport system substrate-binding protein RPA3486 89 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39933498 Common - possible cytochrome P450 hydroxylase superfamily proteins RPA0421 78 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 39935344 Common - putative branched-chain amino acid transport system ATP-binding protein RPA2275 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39937134 Common - putative leucine responsive transcriptional regulator LRP/BkdR, AsnC family RPA4074 149 COG1522 Lrp, Transcriptional regulators Transcription 39933266 Common kgd alpha-ketoglutarate decarboxylase RPA0189 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 39936529 Common - probable UDP-glucose 4-epimerase RPA3467 109 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39933145 Common sppA putative protease IV RPA0065 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 39934368 Common - putative IS5 transposase RPA1293 52 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 39936947 Nonpathogen fliE flagellar hook-basal body protein FliE RPA3886 6 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 39936573 Common - ErfK/YbiS/YcfS/YnhG RPA3511 27 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 39934746 Common cheA3 multidomain chemotaxis histidine kinase CheA3 (Hpt, CheA, CheW, & Resp. Reg. Rec. domains) RPA1676 212 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 39934444 Common - Nitrogen-fixing NifU, C-terminal RPA1370 12 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 39935737 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase RPA2671 153 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 39934029 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase RPA0952 222 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 39933891 Common - hypothetical protein RPA0814 103 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 39937015 Common - thioredoxin reductase RPA3954 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 39935048 Nonpathogen - hypothetical protein RPA1979 3 None None None 39935056 Nonpathogen - hypothetical protein RPA1987 1 None None None 39937140 Nonpathogen - hypothetical protein RPA4080 1 None None None 39934213 Common - Amine oxidase RPA1138 8 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 39934666 Common - possible tryptophan synthase beta chain RPA1596 70 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 39935784 Nonpathogen - hypothetical protein RPA2717 2 None None None 39937165 Common rmrA putative hlyD family multidrug secretion protein RPA4105 153 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39935427 Common - 2OG-Fe(II) oxygenase superfamily RPA2358 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 39935325 Common - transcriptional regulator, ArsR family, ArsR1 RPA2256 67 COG0640 ArsR, Predicted transcriptional regulators Transcription 39933246 Common ctpA putative periplasmic carboxyl-terminal processing protease RPA0169 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 39934740 Common - Metallo-phosphoesterase RPA1670 71 COG0622 COG0622, Predicted phosphoesterase General function prediction only 39936244 Common - Permeases of the drug/metabolite transporter (DMT) superfamily RPA3181 62 None None None 39937683 Common nifZ NifZ domain RPA4625 26 None None None 39937581 Common - response regulator receiver (CheY-like protein) RPA4523 25 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39934184 Common - RNA polymerase ECF-type sigma factor RPA1109 42 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 39933752 Common - possible hydrolase (alpha/beta hydrolase superfamily) RPA0675 28 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39933639 Common - MmgE/PrpD family RPA0562 59 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 39933522 Common - possible HlyC/CorC family of transporters with CBS domains RPA0445 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 39933537 Common - putative esterase RPA0460 112 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 39935772 Common - manganese transport protein MntH RPA2706 106 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 39933957 Common - hypothetical protein RPA0880 19 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 39934066 Common - possible transcriptional regulator, Crp/Fnr family RPA0991 29 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39933444 Common rpoH RNA polymerase factor sigma-32 RPA0367 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 39937081 Common - putative branched-chain amino acid ABC transport system permease protein livm (liv-I protein m) RPA4021 147 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39934912 Common - hypothetical protein RPA1843 79 COG0433 COG0433, Predicted ATPase General function prediction only 39936165 Common - hypothetical protein RPA3102 24 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 39935243 Common - hypothetical protein RPA2174 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 39937029 Common - putative glycosyl transferase 1 RPA3968 181 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 39933450 Common trxC thioredoxin RPA0373 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 39935943 Common - possible MDR related permease RPA2878 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39936953 Nonpathogen - hypothetical protein RPA3892 3 None None None 39936510 Common - enoyl-CoA hydratase RPA3447 135 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39935786 Common - hypothetical protein RPA2719 46 COG2346 COG2346, Truncated hemoglobins General function prediction only 39935390 Common - possible TctB subunit of the Tripartite Tricarboxylate Transporter(TTT) Family RPA2321 6 None None None 39933900 Nonpathogen - Apple domain:N/apple PAN RPA0823 7 None None None 39934201 Common ftsH metalloprotease (cell division protein) FtsH RPA1126 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 39936397 Nonpathogen - hypothetical protein RPA3334 1 None None None 39934398 Nonpathogen - hypothetical protein RPA1324a 2 None None None 39936453 Common hisI phosphoribosyl-AMP cyclohydrolase RPA3390 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 39935279 Common - hypothetical protein RPA2210 67 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 39934400 Common - probable transcriptional regulator, AraC family RPA1326 147 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39933234 Common - hypothetical protein RPA0157 8 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 39933321 Common rpsP 30S ribosomal protein S16 RPA0244 208 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 39933328 Common - MiaB-like tRNA modifying enzyme RPA0251 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 39935078 Common - possible chemotaxis protein motA RPA2009 84 COG1291 MotA, Flagellar motor component Cell motility and secretion 39936344 Common - probable FecR, iron siderophore sensor protein RPA3281 48 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 39934738 Common bchE Mg-protoporphyrin IX monomethyl ester oxidative cyclase 66kD subunit RPA1668 100 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 39934629 Common rbcL ribulose bisophosphate carboxylase RPA1559 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 39934622 Common - hypothetical protein RPA1552 19 COG1633 COG1633, Uncharacterized conserved protein Function unknown 39937842 Common - OmpA/MotB domain RPA4784 155 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 39937192 Common traG1 plasmid transfer factor, traG RPA4132 76 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 39937747 Nonpathogen - hypothetical protein RPA4689 3 None None None 39934593 Common bchC 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase RPA1521 49 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 39937738 Common - putative efflux transporter RPA4680 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 39936418 Common - putative exopolysaccharide polymerization protein RPA3355 144 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 39937062 Common - putative DEAD-box protein, ATP-independent RNA helicase RPA4001 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 39936613 Common - short chain dehydrogenase RPA3551 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 39937176 Common trbG2 conjugal transfer protein trbG RPA4116 50 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 39933471 Common - hypothetical protein RPA0394 7 None None None 39936317 Common rpsG 30S ribosomal protein S7 RPA3254 248 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 39933786 Common - hypothetical protein RPA0709 116 COG1881 COG1881, Phospholipid-binding protein General function prediction only 39933591 Common FarB putative efflux pump protein FarB RPA0514 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39934324 Common - sensor histidine kinase with a response regulator receiver domain RPA1249 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39933716 Common sigE RNA polymerase sigma factor RPA0639 172 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39935726 Common glmS D-fructose-6-phosphate amidotransferase RPA2660 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 39936045 Common - integrase RPA2980 105 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 39936263 Common - putative dual serine/threonine-protein kinase/phosphatase RPA3200 151 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 39937326 Common - possible D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein) RPA4266 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 39936393 Common - hypothetical protein RPA3330 3 None None None 39937320 Common nuoF2 NADH-ubiquinone dehydrogenase chain F RPA4260 159 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 39935680 Common - hypothetical protein RPA2614 30 COG2516 COG2516, Biotin synthase-related enzyme General function prediction only 39937021 Common - hypothetical protein RPA3960 66 COG1432 COG1432, Uncharacterized conserved protein Function unknown 39937314 Common nuoL2 NADH-ubiquinone dehydrogenase chain L RPA4254 205 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 39937426 Common proC pyrroline-5-carboxylate reductase RPA4366 210 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 39934262 Common - NUDIX hydrolase RPA1187 123 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 39934097 Common - possible outer membrane protein RPA1022 89 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 39936066 Common kdpD two component osmosensitive K+channel and sensor histidine kinase, KdpD RPA3001 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 39937061 Common - Adenylate/Guanylate cyclase RPA4000 109 COG3899 COG3899, Predicted ATPase General function prediction only 39936906 Common - possible membrane transport protein RPA3845 176 COG0628 PerM, Predicted permease General function prediction only 39934021 Common cbbG glyceraldehyde-3-phosphate dehydrogenase RPA0944 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 39937873 Common htpG heat shock protein 90 RPA4815 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 39935250 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase RPA2181 125 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 39936214 Common - Heat shock protein DnaJ, N-terminal RPA3151 23 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 39936301 Common rplE 50S ribosomal protein L5 RPA3238 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 39937633 Common - putative ATP-binding protein of sugar ABC transporter RPA4575 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 39936633 Common - two component sensor histidine kinase RPA3571 206 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39933091 Nonpathogen - hypothetical protein RPA0011 1 None None None 39933943 Common rnk putative nucleoside diphosphate kinase regulator RPA0866 93 COG0782 GreA, Transcription elongation factor Transcription 39934988 Common cycH cytochrome c-type biogenesis protein cycH RPA1919 66 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 39935443 Common - possible outer membrane protein RPA2373 111 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 39934079 Nonpathogen - hypothetical protein RPA1004 2 None None None 39934632 Common - transcriptional regulator, LysR family RPA1562 128 COG0583 LysR, Transcriptional regulator Transcription 39935999 Common - hypothetical protein RPA2934 88 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 39933914 Common - conserved hypothetical protein in cyt c oxidase gene clusters RPA0837 26 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 39935682 Common - possible nitrogenase iron-molybdenum cofactor biosynthesis protein NifE homolog RPA2616 39 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39936115 Common purN phosphoribosylglycinamide formyltransferase RPA3052 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 39936034 Nonpathogen - hypothetical protein RPA2969 3 None None None 39934689 Nonpathogen - hypothetical protein RPA1619 2 None None None 39935954 Common - putative peptidyl-prolyl cis-trans isomerse D RPA2889 137 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 39934694 Common - hypothetical protein RPA1624 19 None None None 39933292 Common - possible general stress protein 26 RPA0215 33 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 39936569 Nonpathogen - hypothetical protein RPA3507 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 39936608 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA3546 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39937388 Common - elongation factor G RPA4328 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 39933609 Common - beta-ketothiolase, acetoacetyl-CoA reductase RPA0532 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934164 Nonpathogen - hypothetical protein RPA1089 3 None None None 39934486 Common - putative fatty-acid--CoA ligase RPA1412 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39936562 Common fumC fumarate hydratase RPA3500 202 COG0114 FumC, Fumarase Energy production and conversion 39937033 Common - putative diheme cytochrome c-553 RPA3972 55 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 39935894 Common gid tRNA (uracil-5-)-methyltransferase Gid RPA2827 80 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 39937690 Common nifA Mo/Fe nitrogenase specific transcriptional regulator, NifA RPA4632 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 39933794 Common cobO cob(I)yrinic acid a,c-diamide adenosyltransferase RPA0717 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 39936692 Common - putative prolyl aminopeptidase RPA3630 109 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39937778 Common - hypothetical protein RPA4720 19 None None None 39937742 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA4684 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39935177 Common - response regulator receiver (CheY-like protein) RPA2108 173 COG4566 TtrR, Response regulator Signal transduction mechanisms 39935587 Nonpathogen - hypothetical protein RPA2521 1 None None None 39936824 Common ilvB hypothetical protein RPA3763 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39934430 Common - PpiC-type peptidyl-prolyl cis-trans isomerase RPA1356 62 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 39934591 Common crtE geranylgeranyl pyrophosphate synthase RPA1519 235 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 39933503 Common fabB 3-oxoacyl-(acyl carrier protein) synthase I RPA0426 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934405 Common mqoB malate:quinone oxidoreductase RPA1331 53 COG0579 COG0579, Predicted dehydrogenase General function prediction only 39934870 Common - hypothetical protein RPA1801 20 COG4544 COG4544, Uncharacterized conserved protein Function unknown 39937233 Common - putative diguanylate cyclase (GGDEF) RPA4173 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 39936736 Common - hypothetical protein RPA3674 21 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 39935039 Common - hypothetical protein RPA1970 42 COG3577 COG3577, Predicted aspartyl protease General function prediction only 39933388 Common hisH imidazole glycerol phosphate synthase subunit HisH RPA0311 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 39936193 Common - transcriptional regulator, XRE family RPA3130 31 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 39935821 Common - Polysaccharide deacetylase RPA2754 35 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 39935839 Common rlpA2 rare lipoprotein A RPA2772 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 39936481 Common - hypothetical protein RPA3418 14 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 39935259 Common - ABC transporter, with duplicated ATPase domains RPA2190 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 39937518 Common - hypothetical protein RPA4458 23 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 39936059 Common - transcriptional regulator, LysR family RPA2994 178 COG0583 LysR, Transcriptional regulator Transcription 39935384 Common - putative nickel-dependent hydrogenase, b-type cytochrome subunit RPA2315 44 COG3658 COG3658, Cytochrome b Energy production and conversion 39933969 Common gltD glutamate synthase subunit beta RPA0892 189 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 39933839 Common - possible oligopeptide ABC transporter, periplasmic binding protein component RPA0762 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 39937655 Common - hypothetical protein RPA4597 18 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 39935544 Common - probable transcriptional regulator, AraC family RPA2478 125 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 39935841 Common - penicillin binding protein RPA2774 152 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 39935082 Common - hypothetical protein RPA2013 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 39935100 Common ilvI acetolactate synthase 3 catalytic subunit RPA2031 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 39935658 Common ntrB nitrogen regulatory signal transduction histidine kinase NtrB RPA2592 219 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 39937147 Common - ABC-2 type transport system permease and double ATP-binding protein fusion RPA4087 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 39933399 Common gshB glutathione synthetase RPA0322 130 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 39934344 Nonpathogen - hypothetical protein RPA1269 2 None None None 39937109 Common rfbG cdp-glucose 4,6-dehydratase RPA4049 214 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 39937886 Nonpathogen - hypothetical protein RPA4828 3 None None None 39934940 Common - putative cytochrome P450 RPA1871 65 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 39936295 Common rpmD 50S ribosomal protein L30 RPA3232 89 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 39936677 Common - hypothetical protein RPA3615 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 39934886 Common - hypothetical protein RPA1817 11 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 39935829 Common - hypothetical protein RPA2762 9 COG3548 COG3548, Predicted integral membrane protein Function unknown 39936227 Common - possible chitooligosaccharide deacetylase RPA3164 55 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 39935238 Common rlp1 ribulose-bisphosphate carboxylase-like protein; rubisco-like protein RPA2169 49 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 39936738 Common - putative type IV prepilin peptidase, cpaA RPA3676 12 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 39933315 Nonpathogen - hypothetical protein RPA0238 2 None None None 39933592 Common - possible efflux pump protein FarA RPA0515 118 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 39936707 Common glgX probable glycosyl hydrolase RPA3645 158 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 39936456 Nonpathogen - hypothetical protein RPA3393 8 COG3904 COG3904, Predicted periplasmic protein Function unknown 39936731 Common - putative urea short-chain amide or branched-chain amino acid uptake ABC transporter periplasmic solute-binding protein precursor RPA3669 106 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934947 Common - putative 6-aminohexanoate-dimer hydrolase RPA1878 85 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 39935766 Common recO DNA repair protein RecO RPA2700 55 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 39934880 Common - enoyl CoA hydratase RPA1811 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39937444 Nonpathogen - hypothetical protein RPA4384 1 None None None 39935504 Nonpathogen - hypothetical protein RPA2438 6 None None None 39937881 Common - acyl-CoA synthetase RPA4823 213 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39934510 Nonpathogen anfG dinitrogenase 3 delta subunit RPA1436 5 None None None 39937771 Common - hypothetical protein RPA4713 4 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 39933816 Common cyc putative cytochrome c RPA0739 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 39935205 Nonpathogen - possible cytochrome C precursor RPA2136 5 COG2863 COG2863, Cytochrome c553 Energy production and conversion 39935153 Common cobM precorrin 3 or 4 methylase RPA2084 197 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 39935605 Common - putative acyl-CoA carboxylase biotin-carrying subunit RPA2539 224 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 39937460 Common - possible branched-chain amino acid ABC transport system permease RPA4400 142 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 39937100 Nonpathogen - hypothetical protein RPA4040 1 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39937870 Nonpathogen - possible glutathione S-transferase RPA4812 10 None None None 39935628 Common aapM-1 polar amino acid ABC transport permease protein aapM-1 RPA2562 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 39936450 Common - transcriptional regulator, LysR family RPA3387 168 COG0583 LysR, Transcriptional regulator Transcription 39937111 Common - possible oxo-acyl acyl carrier protein dehydrogenase RPA4051 226 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936109 Common - hypothetical protein RPA3046 56 COG3781 COG3781, Predicted membrane protein Function unknown 39935513 Common - possible biotin synthase RPA2447 73 COG1268 BioY, Uncharacterized conserved protein General function prediction only 39936475 Common - Patatin-like phospholipase domain RPA3412 124 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 39937346 Common - Catalytic LigB subunit of aromatic ring-opening dioxygenase RPA4286 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 39934895 Common - hypothetical protein RPA1826 15 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 39933466 Common mepA penicillin-insensitive murein endopeptidase RPA0389 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 39933143 Common cmk cytidylate monophosphate kinase RPA0063 207 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 39937092 Common purU formyltetrahydrofolate deformylase RPA4032 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 39937278 Nonpathogen - hypothetical protein RPA4218 1 None None None 39933989 Common - hypothetical protein RPA0912 59 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 39933980 Common - possible transcriptional regulator, TetR family RPA0903 29 COG1309 AcrR, Transcriptional regulator Transcription 39935858 Common phaD putative monovalent cation/H+ antiporter subunit D RPA2791 172 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 39933832 Common - putative oligopeptide ABC transporter, ATP-binding component RPA0755 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 39933579 Common - probable HlyC/CorC family of transporters with 2 CBS domains RPA0502 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 39935106 Common - possible periplasmic binding protein RPA2037 114 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935559 Common - possible P-methylase RPA2493 76 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 39935945 Common - hypothetical protein RPA2880 15 None None None 39937610 Common - possible 4-hydroxybutyrate-CoA transferase/hydrolase RPA4552 101 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 39937082 Common - putative branched-chain amino acid ABC transport system, ATP-binding protein RPA4022 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39936148 Common - putative alanine racemase RPA3085 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 39935487 Common - NADH dehydrogenase RPA2421 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 39937591 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase RPA4533 212 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 39933372 Common trmE tRNA modification GTPase TrmE RPA0295 219 COG0486 ThdF, Predicted GTPase General function prediction only 39936751 Common - peptide ABC transporter, permease protein RPA3689 213 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 39936327 Common - Bacterial regulatory protein, MarR family RPA3264 44 COG1846 MarR, Transcriptional regulators Transcription 39935732 Common - possible binding protein component of ABC transporter RPA2666 151 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 39936916 Nonpathogen - hypothetical protein RPA3855 1 None None None 39936155 Common - putative oxidoreductase RPA3092 226 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39936492 Common cysE2 serine acetyltransferase RPA3429 206 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 39935233 Common groEL chaperonin GroEL RPA2164 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 39937458 Common - putative branched-chain amino acid ABC transporter, ATP-binding protein RPA4398 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39933124 Common uppP undecaprenyl pyrophosphate phosphatase RPA0044 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 39933493 Common - enoyl-CoA hydratase RPA0416 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39934608 Nonpathogen ppsR2 transcriptional regulator PpsR2; Fis family RPA1536 9 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 39933239 Common obgE GTPase ObgE RPA0162 249 COG0536 Obg, Predicted GTPase General function prediction only 39933210 Common - ABC sulfate transport system, periplasmic binding protein RPA0133 30 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39936325 Common - putative transporter RPA3262 162 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39934046 Common hupJ putative hydrogenase expression/formation protein hupJ RPA0971 21 None None None 39935248 Common - xanthine-guanine phosphoribosyltransferase RPA2179 48 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 39934601 Common ppsR1 transcriptional regulator PpsR1; Fis family RPA1529 13 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 39936982 Common - possible acetoin dehydrogenase (TPP-dependent) beta chain RPA3921 169 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 39934357 Common - possible transcriptional regulator, ArsR family RPA1282 55 COG0640 ArsR, Predicted transcriptional regulators Transcription 39936856 Common - putative enoyl-CoA hydratase RPA3795 185 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 39936488 Common - Bacterial transferase hexapeptide repeat RPA3425 188 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 39936499 Common - GCN5-related N-acetyltransferase RPA3436 14 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 39936447 Common - possible ABC related periplasmic binding protein RPA3384 7 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 39936465 Common - hypothetical protein RPA3402 18 None None None 39934534 Common - hypothetical protein RPA1462 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 39934719 Common - predicted ABC-type transport systems, involved in lipoprotein release, permease components RPA1649 203 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 39935932 Common - pyruvate dehydrogenase E1 alpha subunit RPA2867 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 39935794 Common ribC riboflavin synthase subunit alpha RPA2727 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 161610771 Common rpsM 30S ribosomal protein S13 RPA3228 239 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 39933198 Nonpathogen - hypothetical protein RPA0121 2 None None None 39936220 Nonpathogen - hypothetical protein RPA3157 4 None None None 39934333 Nonpathogen - hypothetical protein RPA1258 1 None None None 39935887 Common - DUF433 RPA2820 26 COG2442 COG2442, Uncharacterized conserved protein Function unknown 39937823 Common - 2'-deoxycytidine 5'-triphosphate deaminase RPA4765 29 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 39934725 Common - possible urea/short-chain binding protein of ABC transporter RPA1655 54 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39933394 Common - sensor histidine kinase with a response regulator receiver domain RPA0317 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 39936669 Common - transcriptional regulator AbrB/SpoVT family RPA3607 6 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 39936829 Common paaA phenylacetic acid degradation protein paaA RPA3768 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 39937259 Common - putative 2-haloacid halidohydrolase Iva RPA4199 56 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 39936102 Common - possible polysaccharide deacetylase RPA3039 92 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 39937246 Common - Integral membrane protein TerC family RPA4186 75 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 39936760 Common emrB2 putative drug efflux pump, Major Facilitator Superfamily (MFS) RPA3698 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 39934786 Common - putative diguanylate cyclase (GGDEF) RPA1716 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 39933285 Common ispZ intracellular septation protein A RPA0208 87 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 39936774 Common pimD pimeloyl-CoA dehydrogenase (small subunit) RPA3713 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39933181 Common oppB putative dipeptide transport system permease protein 1 RPA0101 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39936788 Common - CorA Metal Ion (Mg2+/Co2+) transporter (MIT) family protein RPA3727 45 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 39936989 Nonpathogen - hypothetical protein RPA3928 1 None None None 39934463 Common - hypothetical protein RPA1389 11 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 39936649 Nonpathogen - hypothetical protein RPA3587 1 None None None 39934549 Common - putative permease protein RPA1477 158 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 39936939 Nonpathogen - hypothetical protein RPA3878 3 None None None 39934898 Common argK arginine/ornithine transport system ATPase RPA1829 101 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 39935107 Common - putative oxidoreductase RPA2038 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 39934931 Common - possible polysaccharide deacetylase RPA1862 91 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 39937406 Common - acetyl-CoA acetyltransferase RPA4346 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 39937237 Nonpathogen - hypothetical protein RPA4177 4 COG5373 COG5373, Predicted membrane protein Function unknown 39936652 Nonpathogen - hypothetical protein RPA3590 5 None None None 39934428 Common - hypothetical protein RPA1354 13 None None None 39936239 Nonpathogen - hypothetical protein RPA3176 2 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 39935569 Common - aminotransferase RPA2503 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 39935677 Common - putative aliphatic sulfonate transport membrane component. Permease subunit of an ABC transporter RPA2611 193 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 39934522 Common - putative oligopeptide ABC transporter (permease) RPA1448 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39937048 Common lpcA possible phosphoheptose isomerase RPA3987 125 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 39934476 Common - putative Glu-tRNA amidotransferase, subunit A RPA1402 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 39935621 Common - Glycosyl transferase, family 39 RPA2555 58 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 39935692 Common - possible hydrolase RPA2626 22 COG2267 PldB, Lysophospholipase Lipid metabolism 39935678 Common msuD alkanesulfonate monooxygenase RPA2612 81 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 39933411 Common dnaJ heat shock protein DnaJ (40) RPA0334 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 39934826 Common - possible oxoacyl carrier protein reductase RPA1757 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39937410 Nonpathogen - hypothetical protein RPA4350 3 None None None 39937430 Common ilvE branched-chain amino acid aminotransferase RPA4370 211 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 39933863 Common - putative Adenylate/Guanylate cyclase RPA0786 79 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 39935093 Common - hypothetical protein RPA2024 16 COG4318 COG4318, Uncharacterized protein conserved in bacteria Function unknown 39936883 Common - hypothetical protein RPA3822 26 COG5467 COG5467, Uncharacterized conserved protein Function unknown 39935285 Nonpathogen - hypothetical protein RPA2216 5 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 39934643 Common - LemA family RPA1573 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 39933771 Common phnH carbon-phosphorus lyase complex subunit RPA0694 37 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 39933783 Nonpathogen - possible endonuclease III RPA0706 34 COG1833 COG1833, Uncharacterized conserved protein Function unknown 39933330 Common - DUF589 RPA0253 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 39934714 Common - hypothetical protein RPA1644 11 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 39936200 Common - Endoribonuclease L-PSP RPA3137 91 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 39934939 Common - possible transcriptional regulator, MarR/EmrR family RPA1870 77 COG1846 MarR, Transcriptional regulators Transcription 39934062 Common - possible branched-chain amino acid ABC transporter, permease protein RPA0987 146 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39937077 Nonpathogen - hypothetical protein RPA4017 3 None None None 39937213 Common fpbB putative iron transport system permease protein RPA4153 154 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 39933366 Common holA DNA polymerase III subunit delta RPA0289 58 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 39935494 Nonpathogen - hypothetical protein RPA2428 1 None None None 39936350 Common - putative 3-oxoacyl-acyl carrier protein reductase RPA3287 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934509 Common anfK alternative nitrogenase 3 beta chain RPA1435 53 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 39934147 Common - hypothetical protein RPA1072 16 COG5451 COG5451, Predicted secreted protein Function unknown 39937403 Common uvrB excinuclease ABC subunit B RPA4343 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 39935114 Common bioB biotin synthetase RPA2045 179 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 39937489 Common - Uncharacterized iron-regulated membrane protein DUF337 RPA4429 14 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 39937524 Common soxC sulfite dehydrogenase RPA4464 90 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 39937117 Common - possible dolichol phosphate mannose synthase RPA4057 166 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39933611 Common - hypothetical protein RPA0534 53 COG3577 COG3577, Predicted aspartyl protease General function prediction only 39935644 Common - possible alginate o-acetyltransferase AlgJ RPA2578 13 None None None 39936845 Common - putative dolichol-phosphate mannosyltransferase RPA3784 144 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 39933824 Common cysA putative sulfate ABC transporter, ATP-binding component RPA0747 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 39936477 Common - putative hydroxamate-type ferrisiderophore receptor RPA3414 117 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39936871 Common livK putative periplasmic binding protein of ABC transporter RPA3810 136 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39935869 Common - ATP-dependent DNA helicase RPA2802 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 39933854 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS domain RPA0777 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39934676 Common - hypothetical protein RPA1606 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 39934807 Common - putative branched-chain amino acid transport system ATPase RPA1738 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 39935833 Common - Phenylacetic acid degradation-related protein:Thioesterase superfamily RPA2766 38 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 39933280 Common cycV heme exporter protein A (heme ABC transporter ATP-binding protein), cytochrome c biogenesis RPA0203 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 39934982 Common - hypothetical protein RPA1913 19 None None None 39935469 Nonpathogen - hypothetical protein RPA2402 2 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39935848 Common dctQ2 TrapT dctQ-M fusion permease, dicarboxylate transport RPA2781 124 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 39934836 Common - sensor histidine kinase with a PAC motif and a response regulator receiver domain RPA1767 213 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 39933336 Nonpathogen - HTransmembrane sensor and HAMP domains RPA0259 2 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39936868 Common livM putative permease of ABC transporter (high-affinity branched-chain amino acid transport) RPA3807 145 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 39937504 Common - hypothetical protein RPA4444 31 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 39937496 Common - hypothetical protein RPA4436 69 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 39937783 Common - hypothetical protein RPA4725 8 None None None 39936128 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase RPA3065 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 39935222 Common - aldehyde dehydrogenase RPA2153 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 39934290 Common - putative ABC transporter, permease protein RPA1215 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 39936420 Common - putative glycosyltransferase RPA3357 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 39934775 Common - possible 3-hydroxyacyl-CoA dehydrogenase type II RPA1705 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 39934480 Common - hypothetical protein RPA1406 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 39934059 Common glnA4 putative glutamine synthetase-like protein RPA0984 222 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 39934972 Common GTA homologue of Rhodobacter capsulatus gene transfer agent (GTA) orfg12 RPA1903 25 COG5448 COG5448, Uncharacterized conserved protein Function unknown 39935198 Common - possible energy transducer TonB, C-terminal region RPA2129 48 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 39937718 Common otsA putative alpha,alpha-trehalose-phosphate synthase (UDP-forming) (trehalose-6-phosphate synthase) RPA4660 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 39936781 Common ilvF putative branched-chain amino acid transport system ATP-binding protein RPA3720 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 39937182 Common - Conjugal transfer protein TrbD RPA4122 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 39935480 Common - putative urea/short-chain amide transport system ATP-binding protein RPA2413 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 39935029 Common - putative RND efflux membrane protein RPA1960 116 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 39937606 Nonpathogen - hypothetical protein RPA4548 1 None None None 39936320 Common - probable transcriptional regulator, AraC family RPA3257 68 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 39936746 Common - TPR repeat RPA3684 33 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 39936819 Common hpcG 2-oxo-hepta-3-ene-1,7-dioate hydratase RPA3758 64 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 39935630 Nonpathogen - hypothetical protein RPA2564 1 None None None 39934134 Common - probable outer membrane protein, TonB-dependent receptor RPA1059 106 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 39936281 Common - hypothetical protein RPA3218 124 COG0432 COG0432, Uncharacterized conserved protein Function unknown 39933359 Common - Cyclic nucleotide binding protein RPA0282 52 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 39935068 Common - GCN5-related N-acetyltransferase:Aminotransferase, class-II RPA1999 31 COG0456 RimI, Acetyltransferases General function prediction only 39935966 Nonpathogen - hypothetical protein RPA2901 1 COG4128 Zot, Zonula occludens toxin General function prediction only 39935460 Common - RNA polymerase ECF-type sigma factor, possible FecI RPA2391 49 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 39937706 Common - possible ABC transporter binding protein component RPA4648 71 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 39937488 Common - putative glucosyltransferase I; lipopolysaccharide core biosynthesis RPA4428 11 None None None 39936232 Common lipB lipoyltransferase RPA3169 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 39936047 Common - possible insertion element ISR1 hypothetical 10 KD protein A3 RPA2982 58 None None None 39934156 Nonpathogen - hypothetical protein RPA1081 1 None None None 39936360 Common - possible branched-chain amino acid transport system substrate-binding protein RPA3297 114 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 39934000 Common - hypothetical protein RPA0923 35 COG3752 COG3752, Predicted membrane protein Function unknown 39933991 Common - putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL) with PAS domain RPA0914 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 39937573 Common - hypothetical protein RPA4515 60 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 39934383 Nonpathogen - hypothetical protein RPA1308 2 None None None 39933760 Common - possible ABC transporter permease component RPA0683 138 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 39936811 Common - methyl-accepting chemotaxis receptor/sensory transducer RPA3750 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 39933486 Common - NAD binding site:Amine oxidase RPA0409 30 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 39936332 Common rplL 50S ribosomal protein L7/L12 RPA3269 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 39936042 Common nrd ribonucleotide-diphosphate reductase subunit alpha RPA2977 158 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 39937242 Common pntA nicotinamide nucleotide transhydrogenase, subunit alpha1 RPA4182 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 39935505 Nonpathogen - hypothetical protein RPA2439 3 None None None 39933370 Common gidB putative glucose inhibited division protein B (GidB) RPA0293 184 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 39935134 Common nosL putative nosL (possibly a disulfide isomerase) RPA2065 26 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 39933425 Common - possible hydrolase RPA0348 149 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 39935215 Common - putative long-chain-fatty-acid--CoA ligase RPA2146 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 39935715 Common - hypothetical protein RPA2649 15 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 39936313 Common rplC 50S ribosomal protein L3 RPA3250 235 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 39934659 Common rpsD 30S ribosomal protein S4 RPA1589 243 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 39933261 Common - hypothetical protein RPA0184 12 None None None 39934241 Common - N-6 Adenine-specific DNA methylase:Conserved hypothetical protein 95 RPA1166 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 39935374 Common - acyl-CoA dehydrogenase RPA2305 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 39935973 Common - Cytidine/deoxycytidylate deaminase:Tat pathway signal RPA2908 186 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 39937617 Common - putative citrate lyase beta chain RPA4559 109 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 39934005 Nonpathogen - hypothetical protein RPA0928 4 None None None 39933684 Common hemK putative protoporphyrinogen oxidase, hemK protein RPA0607 212 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 39936134 Common - DUF175 RPA3071 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 39934904 Common mutB methylmalonyl-CoA mutase RPA1835 111 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism