Wolinella succinogenes DSM 1740, complete genome NC_005090 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 34558483 Common tig trigger factor WS2209 203 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 34557781 Common - PUTATIVE PERIPLASMIC BINDING PROTEIN WS1435 104 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 34557228 Common FRDC FUMARATE REDUCTASE CYTOCHROME B SUBUNIT WS0832 10 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 34558300 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase WS2013 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 34557171 Common - PUTATIVE OUTER MEMBRANE CHANNEL PROTEIN WS0771 135 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 34556808 Common - PUTATIVE PERIPLASMIC PROTEIN WS0375 27 COG2859 COG2859, Uncharacterized protein conserved in bacteria Function unknown 34556611 Common - PUTATIVE FLAVOPROTEIN WS0163 91 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 34557639 Common - phosphatidylserine decarboxylase WS1275 86 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 34557855 Common RACS TWO-COMPONENT SENSOR HISTIDINE KINASE WS1522 188 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34557632 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS1268 58 COG1971 COG1971, Predicted membrane protein Function unknown 34557491 Common - hypothetical protein WS1114 55 COG3665 COG3665, Uncharacterized conserved protein Function unknown 34556908 Common NUOJ NADH dehydrogenase subunit J WS0483 145 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 34556993 Common - hypothetical protein WS0574 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 34557920 Common - hypothetical protein WS1599 9 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 34558413 Common porD pyruvate flavodoxin oxidoreductase subunit delta WS2131 51 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 34558082 Common - LIPOPROTEIN WS1775 45 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 34557094 Common GMHA PHOSPHOHEPTOSE ISOMERASE WS0681 124 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 34558390 Common - hypothetical protein WS2107 14 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 34557662 Common proA GAMMA-GLUTAMYL PHOSPHATE REDUCTASE WS1300 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 34557212 Common - hypothetical protein WS0814 37 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 34556574 Common - GGDEF FAMILY PROTEIN WS0125 161 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 34557946 Common - RESPONSE REGULATOR PROTEIN-CheY-like nd an HD-GYP domain WS1630 126 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 34556564 Common - coproporphyrinogen III oxidase WS0113 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 34558472 Common - hypothetical protein WS2197 5 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 34557382 Nonpathogen fumC hypothetical protein WS0994 6 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 34556757 Common - COMPETENCE PROETIN 1 WS0322 111 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 34557203 Common - hypothetical protein WS0805 2 None None None 34557316 Common - hypothetical protein WS0927 22 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 34557292 Common MEXC MEMBRANE FUSION PROTEIN MEXC RND MULTIDRUG EFFLUX MEMBRANE FUSIONPROTEIN MEXC WS0902 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 34557451 Common oorA 2-oxoglutarate-acceptor oxidoreductase subunit OorA WS1068 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 34556942 Common - hypothetical protein WS0520 5 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 34558200 Common WAAQ PUTATIVE HEPTOSYLTRANSFERASE III WAAQ WS1906 79 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 34557824 Common - hypothetical protein WS1485 4 None None None 34558321 Nonpathogen - hypothetical protein WS2035 1 None None None 34558315 Nonpathogen - hypothetical protein WS2029 1 None None None 34558432 Common CYTB UBIQUINOL CYTOCHROME C OXIDOREDUCTASE, CYTOCHROME B SUBUNIT (FBCH) WS2153 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 34557416 Common pgk phosphoglycerate kinase WS1030 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 34556668 Common RECJ PUTATIVE SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE WS0225 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 34557745 Common NIFH DINITROGENASE REDUCTASE SUBUNIT WS1394 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 34557213 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA WS0815 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 34556834 Common NIMA hypothetical protein WS0404 19 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 34557275 Common EXBB BIOPOLYMER TRANSPORT PROTEIN EXBB WS0885 120 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 34556531 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0077 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34558338 Nonpathogen - hypothetical protein WS2053 1 None None None 34557062 Common - cobalt transport protein CbiM WS0646 24 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 34558256 Common - hypothetical protein WS1968 21 None None None 34557299 Nonpathogen - hypothetical protein WS0909 1 None None None 34558265 Common - PUTATIVE HEMOLYSIN WS1977 50 COG3176 COG3176, Putative hemolysin General function prediction only 34558243 Common - conserved hypothetical protein-Outer membrane receptor protein WS1953 82 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 34557956 Common - hypothetical protein WS1640 4 None None None 34557057 Common - TRANSCRIPTIONAL ACTIVATOR PROTEIN COPR WS0641 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34558261 Common - conserved hypothetical protein-TPR repeat containing protein WS1973 12 COG4105 ComL, DNA uptake lipoprotein General function prediction only 34557943 Common - INTEGRAL MEMBRANE PROTEIN-Predicted permeases WS1626 110 COG0730 COG0730, Predicted permeases General function prediction only 34557478 Common - hypothetical protein WS1100 3 None None None 34557164 Common DSRP hypothetical protein WS0763 9 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 34557230 Common - hypothetical protein WS0834 13 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 34556948 Common - acyl-carrier-protein S-malonyltransferase WS0527 207 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 34557812 Common LIVH ABC TRANSPORT SYSTEM PERMEASE PROTEIN WS1470 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 34557508 Common HSDS-3 PROBABLE TYPE I RESTRICTION ENZYME S PROTEIN WS1134 36 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 34557563 Common ribA GTP cyclohydrolase II WS1194 176 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 34557359 Common MREB PUTATIVE ROD SHAPE-DETERMINING PROTEIN (FRAGMENT) WS0971 219 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 34557335 Common PSTA PHOSPHATE TRANSPORT PERMEASE WS0946 224 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 34556510 Common - PUTATIVE PERIPLASMIC PROTEIN WS0056 11 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 34557180 Common - DNA-3-METHYLADENINE GLYCOSYLASE I WS0781 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 34558318 Nonpathogen - hypothetical protein WS2032 1 None None None 34557729 Common - hypothetical protein WS1377 6 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 34558428 Common coaE dephospho-CoA kinase WS2149 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 34557819 Common PYRC2 dihydroorotase WS1479 203 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 34557375 Common OPP-1D PUTATIVE OLIGOPEPTIDE TRANSPORTER WS0987 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 34558343 Common UPPS PUTATIVE UNDECAPRENYL DIPHOSPHATE SYNTHASE WS2058 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 34558128 Common FADE16 PUTATIVE ACYL-CoA DEHYDROGENASE WS1829 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 34557111 Common - hypothetical protein WS0700 21 COG2863 COG2863, Cytochrome c553 Energy production and conversion 34557280 Common - hypothetical protein WS0890 79 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 34556546 Common - LIN1802 PROTEIN WS0093 121 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 34557045 Common FABB 3-oxoacyl-(acyl carrier protein) synthase II WS0629 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 34556477 Common PLDA OUTER MEMBRANE PHOSPHOLIPASE A PRECURSOR WS0018 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 34557123 Common - FERREDOXIN OXIDOREDUCTASE WS0713 77 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 34557498 Common - ABC-TYPE IRON (III) TRANSPORT SYSTEM WS1123 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 34558465 Common WBPI PUTATIVE UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE WBPI WS2189 151 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 34558118 Common - HISTIDINE KINASE SENSOR PROTEIN WS1818 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34558353 Common - conserved hypothetical protein-PREDICTED HAD SUPEFAMILY PROTEINS WS2069 103 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 34557183 Common aspB PUTATIVE AMINOTRANSFERASE PROTEIN WS0784 161 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 34557282 Common - hypothetical protein WS0892 2 COG2863 COG2863, Cytochrome c553 Energy production and conversion 34558132 Common - hypothetical protein WS1833 21 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 34556538 Common glyA serine hydroxymethyltransferase WS0085 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 34558224 Common - hypothetical protein WS1930 51 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 34557629 Common YBTQ YBTQ PROTEIN WS1265 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 34557024 Common - PROTEASE WS0608 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 34557568 Common mogA molybdenum cofactor biosynthesis protein WS1199 187 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 34556626 Common CCOO CB-TYPE CYTOCHROME C OXIDASE SUBUNIT II WS0179 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 34558207 Common - conserved hypothetical protein-TPR repeat-containing WS1913 55 None None None 34557600 Common - hypothetical protein WS1235 6 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 34556679 Common pyrH uridylate kinase WS0238 239 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 34558029 Common rnhB RIBONUCLEASE HII RNASE HII WS1718 221 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 34558169 Common - DNA polymerase III subunit delta WS1874 7 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 34557134 Nonpathogen - hypothetical protein WS0729 1 None None None 34557959 Common FOLK PYROPHOSPHOKINASE-7,8-dihydro-6- hydroxymethylpterin-pyrophosphokinase WS1643 174 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 34557803 Common - hypothetical protein WS1459 46 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 34556690 Common - PROBABLE GALACTOSYLTRANSFERASE WS0250 224 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 34556517 Common - hypothetical protein WS0063 7 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 34557350 Common - hypothetical protein WS0962 3 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 34556850 Common - CATION-TRANSPORTING ATPASE (P-TYPE) WS0421 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 34557895 Common - hypothetical protein WS1569 3 None None None 34557972 Common - conserved hypothetical protein-Organic radical activating enzyme WS1656 169 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 34556519 Common ksgA dimethyladenosine transferase WS0065 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 34556893 Common rpsL 30S ribosomal protein S12 WS0468 227 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 34558378 Common - hypothetical protein WS2095 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 34557341 Common - hypothetical protein WS0953 207 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 34558376 Common fliP flagellar biosynthesis protein FliP WS2093 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 34558431 Common PETA PUTATIVE UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT WS2152 111 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 34556541 Common CAC3163 ANTHRANILATE SYNTHASE COMPONENT I WS0088 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 34558162 Nonpathogen - hypothetical protein WS1867 2 COG1434 COG1434, Uncharacterized conserved protein Function unknown 34556604 Common - hypothetical protein WS0156 148 COG1576 COG1576, Uncharacterized conserved protein Function unknown 34558066 Common flgE flagellar hook protein FlgE WS1759 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 34556985 Common xseA exodeoxyribonuclease VII large subunit WS0566 198 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 34557196 Common lpxB lipid-A-disaccharide synthase WS0798 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 34558271 Common dnaE DNA polymerase III subunit alpha WS1983 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 34557767 Common - PERIPLASMIC COMPONENT OF EFFLUX SYSTEM WS1419 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 34557036 Common prmA ribosomal protein L11 methyltransferase WS0620 172 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 34557907 Common - POLYPRENYL SYNTHETASE ) WS1582 237 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 34557367 Common - OLIGOPEPTIDE ABC TRANSPORTER PERMEASE WS0979 184 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 34556675 Common - hypothetical protein WS0233 94 None None None 34558299 Common minC septum formation inhibitor WS2012 11 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 34557155 Common - hypothetical protein WS0754 94 COG0701 COG0701, Predicted permeases General function prediction only 34557070 Common mtnK methylthioribose kinase WS0654 28 COG4857 COG4857, Predicted kinase General function prediction only 34557243 Common - hypothetical protein WS0847 80 COG1846 MarR, Transcriptional regulators Transcription 34556796 Common PPIA PEPTIDYL-PROLYL CIS-TRANS ISOMERASE WS0363 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 34557673 Common - hypothetical protein WS1312 4 None None None 34557880 Common - hypothetical protein WS1552 31 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 34557940 Common - conserved hypothetical protein-Predicted kinase WS1623 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 34557005 Common - succinyl-diaminopimelate desuccinylase WS0588 205 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 34557888 Common - INTEGRAL MEMBRANE PROTEIN-Permease Component, involved in lipoprotein release WS1560 32 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 34558142 Common fdhB HYDROGENASE-3 SMALL SUBUNIT WS1843 142 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 34558034 Common - hypothetical protein WS1724 66 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 34558043 Common glyS hypothetical protein WS1733 2 None None None 34558054 Common - PROTEIN DISULPHIDE ISOMERASE WS1747 3 None None None 34557487 Common - ABC TRANSPORTER, PERIPLASMIC SUBSTRATE-BINDING PROTEIN WS1110 65 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 34558122 Common - hypothetical protein WS1822 34 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 34557441 Common FLIN flagellar motor switch protein WS1058 117 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 34558111 Common MODA MOLYBDATE-BINDING LIPOPROTEIN WS1810 148 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 34556911 Common - NADH dehydrogenase subunit M WS0487 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 34556859 Common - PUTATIVE MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN WS0432 64 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556738 Common argD SUCCINYLORNITHINE TRANSAMINASE WS0302 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 34557690 Common - hypothetical protein WS1330 5 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 34557634 Common - PUTATIVE EFFLUX TRANSPORTER WS1270 115 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 34558053 Common AHPC1 ALKYL HYDROPEROXIDE REDUCTASE WS1744 212 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 34556555 Common ILVI acetolactate synthase 3 catalytic subunit WS0103 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 34556930 Common BIRA biotin--protein ligase WS0508 87 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 34557072 Common RHPR TWO COMPONENT RESPONSE REGULATOR WS0657 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34556710 Common - LYTIC MUREIN TRANSGLYCOSYLASE WS0272 133 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 34558081 Common - hypothetical protein WS1774 2 None None None 34556964 Common - MSHA BIOGENESIS PROTEIN MSHG WS0544 149 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 34558443 Common - hypothetical protein WS2166 5 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 34557315 Common - hypothetical protein WS0926 36 None None None 34556922 Common HU PUTATIVE DNA-BINDING PROTEIN II (HB) WS0499 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 34558424 Common - hypothetical protein WS2144 2 None None None 34558137 Common nuoD HYDROGENASE 4 SUBUNIT WS1838 191 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 34556877 Common HOM homoserine dehydrogenase WS0450 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 34557101 Common - hypothetical protein WS0690 14 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 34558006 Common RPSK 30S ribosomal protein S11 WS1694 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 34557605 Common - hypothetical protein WS1240 37 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 34556820 Common - hypothetical protein WS0389 9 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 34558383 Common RPON RNA polymerase factor sigma-54 WS2100 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 34556865 Common ddl D-alanyl-alanine synthetase A WS0438 206 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 34557434 Common PURN PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE WS1050 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 34556472 Common - hypothetical protein WS0013 23 None None None 34557758 Common thrS hypothetical protein WS1408 12 None None None 34557079 Common - hypothetical protein WS0665 24 COG0456 RimI, Acetyltransferases General function prediction only 34557914 Common - PUTATIVE HISTIDINE KINASE SENSOR PROTEIN WS1590 172 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34556593 Common trmB tRNA (guanine-N(7))-methyltransferase WS0145 174 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 34558290 Common - tRNA 2-selenouridine synthase WS2003 65 COG2603 COG2603, Predicted ATPase General function prediction only 34557001 Common - hypothetical protein WS0584 4 None None None 34557983 Common - AMIDASE-Related to nicotinamidase WS1670 88 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 34557861 Common - tartrate dehydratase subunit alpha WS1530 140 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 34558033 Common - ALPHA-D-MANNOSE-ALPHA(1-6)PHOSPHATIDYL MYO-INOSITO WS1723 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 34558147 Common - DIMETHYL SULFOXIDE REDUCTASE PRECURSOR DMSO REDUCTASEDMSOR WS1849 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34557991 Common ISPA GERANYLGERANYL PYROPHOSPHATE SYNTHASE WS1679 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 34557424 Common - hypothetical protein WS1039 7 None None None 34556719 Common TNPA TRANSPOSASE WS0282 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557656 Common hslU ATP-dependent protease ATP-binding subunit WS1293 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 34558453 Common - hypothetical protein WS2177 83 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 34557589 Common - SCAFFOLDING PROTEIN FOR MUREIN-SYNTHESIZING HOLOENZYME PUTATIVE OUTERMEMBRANE PROTEIN WS1223 32 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 34558386 Common uvrA hypothetical protein WS2103 13 None None None 34557695 Common - PUTATIVE MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN WS1337 39 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557357 Common nrfA cytochrome c nitrite reductase WS0969 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 34557480 Common - ATP-BINDING PROTEIN WS1102 101 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 34558501 Common thyX FAD-dependent thymidylate synthase WS2228 51 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 34556652 Common glyS glycyl-tRNA synthetase subunit beta WS0209 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 34557573 Common - SENSORY BOX/GGDEF FAMILY PROTEIN WS1205 193 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34557368 Nonpathogen - hypothetical protein WS0980 1 None None None 34557873 Common - hypothetical protein WS1545 60 COG1683 COG1683, Uncharacterized conserved protein Function unknown 34557129 Common - PENICILLIN-BINDING PROTEIN WS0721 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 34557939 Common recN DNA REPAIR PROTEIN-ATPASE WS1622 210 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 34556493 Common PGLF PUTATIVE SUGAR EPIMERASE/DEHYDRATASE WS0036 139 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 34558174 Common MIND SEPTUM SITE-DETERMINING PROTEIN MIND CELL DIVISION INHIBITOR MIND WS1879 162 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 34558061 Common - endonuclease IV WS1754 100 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 34556745 Common groES co-chaperonin GroES WS0309 210 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 34556633 Common - hypothetical protein WS0187 6 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 34557325 Common TTRB TTRB WS0936 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34558088 Common aspS aspartyl-tRNA synthetase WS1781 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34556634 Common gmk guanylate kinase WS0188 212 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 34556505 Common - WLAC PROTEIN WS0050 200 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 34558100 Common - hypothetical protein WS1797 17 None None None 34558213 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR WS1919 191 COG0583 LysR, Transcriptional regulator Transcription 34558105 Common MODC MOLYBDENUM TRANSPORT ATP-BINDING PROTEIN WS1803 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 34557251 Common ectC L-ectoine synthase WS0856 35 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 34558402 Common - hypothetical protein WS2119 40 COG1578 COG1578, Uncharacterized conserved protein Function unknown 34557545 Common NAPB PERIPLASMIC NITRATE REDUCTASE SMALL SUBUNIT CYTOCHROME C-TYPEPROTEIN WS1174 29 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 34556609 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase WS0161 129 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 34557064 Common - hypothetical protein WS0648 11 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 34556827 Common - hypothetical protein WS0396 13 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 34557514 Nonpathogen - hypothetical protein WS1142 1 None None None 34558484 Common clpP ATP-dependent Clp protease proteolytic subunit WS2210 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 34557253 Common MCPG PUTATIVE CHEMOTAXIS CHEMORECEPTOR MCPG WS0859 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557835 Nonpathogen - hypothetical protein WS1498 1 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 34556666 Common - PUTATIVE ZINC-METALLO PROTEASE WS0223 65 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 34558234 Common - ABC TRANSPORT ATP-BINDING PROTEIN WS1943 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 34557361 Common - hypothetical protein WS0973 65 COG1971 COG1971, Predicted membrane protein Function unknown 34557999 Common HYDA NI/FE-HYDROGENASE SMALL SUBUNIT WS1687 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 34557967 Common - flagellar assembly protein FliW WS1651 15 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 34558167 Common SSB single-strand DNA-binding protein WS1872 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 34556725 Common fecA FERRICHROME-IRON RECEPTOR WS0289 106 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 34557730 Common KTRA PUTATIVE K+ UPTAKE PROTEIN WS1378 131 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 34557697 Common - hypothetical protein WS1339 221 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 34558070 Common TYPA GTP-BINDING PROTEIN-GTPase involved in stress response WS1763 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 34558364 Common - transaldolase WS2080 135 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 34557736 Common hydA hypothetical protein WS1384 9 None None None 34558307 Nonpathogen - hypothetical protein WS2020 1 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 34556768 Common lysA DIAMINOPIMELATE DECARBOXYLASE DAP DECARBOXYLASE WS0333 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 34557239 Common - PUTATIVE SIGNAL TRANSDUCTION PROTEIN WS0843 107 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557398 Common - hypothetical protein WS1011 9 COG3205 COG3205, Predicted membrane protein Function unknown 34558185 Common RPOD RNA polymerase sigma factor RpoD WS1890 217 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 34557265 Nonpathogen - hypothetical protein WS0871 1 None None None 34557190 Common hypC HYDROGENASE EXPRESSION/FORMATION PROTEIN WS0792 91 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 34557376 Common - OLIGOPEPTIDE ABC TRANSPORTER ATP-BINDING PROTEIN WS0988 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 34556588 Common - hypothetical protein WS0140 27 COG3875 COG3875, Uncharacterized conserved protein Function unknown 161760547 Common - hydroxylamine reductase WS1183 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 34556903 Common - NADH dehydrogenase subunit G WS0478 184 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 34558283 Common - 1-deoxy-D-xylulose-5-phosphate synthase WS1996 210 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 34557448 Common SUCC SUCCINYL-COA SYNTHETASE BETA CHAIN WS1065 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 34556752 Common - hypothetical protein WS0316 7 COG1714 COG1714, Predicted membrane protein/domain Function unknown 34557034 Common hisA PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDEISOMERASE WS0618 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 34558160 Common DCTM LARGE INTEGRAL C4-DICARBOXYLATE MEMBRANE TRANSPORT PROTEIN,PUTATIVE WS1865 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 34557011 Common YLNA hypothetical protein WS0594 5 None None None 34556659 Common - hypothetical protein WS0216 7 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 34558490 Common gltX glutamyl-tRNA synthetase WS2217 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 34557380 Common - hypothetical protein WS0992 8 None None None 34558090 Common - CINA-RELATED PROTEIN WS1783 128 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 34557703 Common - hypothetical protein WS1347 81 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 34556975 Common - hypothetical protein WS0556 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 34558322 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase WS2037 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 34557927 Common uvrC excinuclease ABC subunit C WS1607 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 34557658 Common rplI 50S ribosomal protein L9 WS1295 214 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 34557646 Nonpathogen - hypothetical protein WS1282 1 None None None 34556503 Nonpathogen - hypothetical protein WS0048 2 COG3233 COG3233, Predicted deacetylase General function prediction only 34556782 Common - hypothetical protein WS0347 20 None None None 34558295 Nonpathogen - hypothetical protein WS2008 3 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 34557617 Common - CO-CHAPERONE-CURVED DNA BINDING PROTEIN A (CBPA) WS1253 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 161760543 Common moaA molybdenum cofactor biosynthesis protein A WS2006 203 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 34558275 Common - conserved hypothetical protein-MOXR LIKE ATPASES WS1987 179 COG0714 COG0714, MoxR-like ATPases General function prediction only 34557766 Common - PROBABLE TRANSMEMBRANE ATP-BINDING ABC TRANSPORTER PROTEIN WS1418 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 34556644 Common - hypothetical protein WS0200 120 COG0398 COG0398, Uncharacterized conserved protein Function unknown 34556763 Common rpmB 50S ribosomal protein L28 WS0328 148 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 34556731 Common ribH riboflavin synthase subunit beta WS0295 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 34557822 Common - hypothetical protein WS1483 234 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 34557911 Common HISD HISTIDINOL DEHYDROGENASE WS1587 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 34556527 Common - PUTATIVE LIPOPROTEIN THIREDOXIN WS0073 119 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 34556802 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0369 25 COG2862 COG2862, Predicted membrane protein Function unknown 34556934 Common ATPF F0F1 ATP synthase subunit B WS0512 7 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 34556683 Common - hypothetical protein WS0242 125 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 34557389 Common - CHEMOTAXIS PROTEIN (TLPB) WS1002 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557041 Nonpathogen - hypothetical protein WS0625 1 None None None 34557201 Common - pantothenate kinase WS0803 22 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 34558328 Common FUR FERRIC UPTAKE REGULATION PROTEIN FERRIC UPTAKE REGULATOR WS2043 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 34557814 Common - PUTATIVE RNA METHYLASE WS1472 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 34557485 Common TNPA PUTATIVE TRANSPOSASE WS1108 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34558254 Common - conserved hypothetical protein-N6-adenine-specific methylase WS1966 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 34557791 Common - hypothetical protein WS1446 2 None None None 34556792 Common - hypothetical protein WS0358 4 None None None 34557778 Common mraY hypothetical protein WS1432 2 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 34557114 Common - hypothetical protein WS0703 77 None None None 34556832 Common PATB AMINOTRANSFERASE WS0402 235 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 34556988 Common - PUTATIVE PERMEASE OF ABC TRANSPORTER WS0569 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 34558248 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS1958 105 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557162 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCP WS0761 134 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34558267 Common - PUTATIVE RIBOSOMAL PSEUDOURIDINE SYNTHASE WS1979 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 34557401 Common - PUTATIVE EFFLUX PROTEIN WS1014 223 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 34558263 Common PROC pyrroline-5-carboxylate reductase WS1975 210 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 34556906 Common NUOH NADH dehydrogenase subunit H WS0481 191 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 34556781 Common - hypothetical protein WS0346 129 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 34558241 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS1951 106 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557476 Common - hypothetical protein WS1098 2 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 34556602 Common - hypothetical protein WS0154 7 None None None 34558456 Common - hypothetical protein WS2180 11 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 34558336 Common - hypothetical protein WS2051 10 COG2952 COG2952, Uncharacterized protein conserved in bacteria Function unknown 34556784 Common - PUTATIVE OUTER MEMBRANE PROTEIN WS0350 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 34557435 Common - hypothetical protein WS1051 3 None None None 34557219 Common infC translation initiation factor IF-3 WS0821 210 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 34557015 Common actP acetate permease WS0598 185 COG4147 DhlC, Predicted symporter General function prediction only 34557923 Common hemD uroporphyrinogen-III synthase WS1602 9 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 34558415 Common - PUTATIVE HYDROLASE WS2133 186 COG0546 Gph, Predicted phosphatases General function prediction only 34557226 Common sdhB succinate dehydrogenase iron-sulfur subunit WS0830 198 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 34556512 Common clpX ATP-dependent protease ATP-binding subunit WS0058 218 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 34557344 Common FEOB FERROUS IRON TRANSPORT PROTEIN WS0956 188 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 34557808 Common - hypothetical protein WS1465 147 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 34557727 Common - TWO-COMPONENT HYBRID SENSOR AND REGULATOR WS1375 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34556576 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0127 44 None None None 34557493 Common - PROBABLE TRANSMEMBRANE PROTEIN WS1117 34 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 34557521 Common fdhD formate dehydrogenase accessory protein WS1149 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 34557833 Common - hypothetical protein WS1496 4 None None None 34556613 Common - GLPM PROTEIN WS0165 14 COG3136 GlpM, Uncharacterized membrane protein required for alginate biosynthesis General function prediction only 34558392 Common - SIALIC ACID SYNTHASE WS2109 79 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 34557630 Common - hypothetical protein WS1266 89 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 34558355 Common - RARE LIPOPROTEIN A RLPA WS2071 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 34556940 Common EXBB3 EXBB\TOLQ FAMILY TRANSPORT PROTEIN WS0518 137 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 34557391 Common - hypothetical protein WS1004 166 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 34556929 Common fmt methionyl-tRNA formyltransferase WS0507 214 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 34557232 Common NIFS NIFS PROTEIN (FRAGMENT) WS0836 22 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 34557877 Common - PHOSPHATE-BINDING PROTEIN OF PHOSPHONATE ABC TRANSPORTER WS1549 76 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 34558397 Common - MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN WS2114 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556951 Common PILT Pilin biogenesis WS0530 167 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 34557853 Common - HYPOTHETICAL PROTEIN-Methyl-accepting chemotaxis protein WS1520 94 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556839 Common - AMMONIUM TRANSPORTER, AMTB WS0410 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 34557318 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS0929 104 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557641 Common - MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE C WS1277 153 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 34556677 Common - hypothetical protein WS0236 74 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 34557392 Common - hypothetical protein WS1005 58 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 34556619 Common - MALIC ENZYME WS0171 193 COG0281 SfcA, Malic enzyme Energy production and conversion 34557043 Common - hypothetical protein WS0627 9 None None None 34556915 Common - hypothetical protein WS0492 4 None None None 34557743 Common NIFD NIFD WS1392 50 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 34556771 Common - hypothetical protein WS0336 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 34557152 Common - hypothetical protein WS0751 158 COG0640 ArsR, Predicted transcriptional regulators Transcription 34556759 Common alaS alanyl-tRNA synthetase WS0324 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557701 Common FOLD METHYLENETETRAHYDROFOLATE DEHYDROGENASE/METHENYLTETRAHYDROFOLATECYCLOHYDROLASE WS1345 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 34557897 Common fdhA hypothetical protein WS1572 5 None None None 34558438 Common - CYTOCHROME C BIOGENESIS PROTEIN (YCF5) WS2159 112 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 34557506 Common - hypothetical protein WS1132 31 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 34557722 Common - PUTATIVE PERIPLASMIC PROTEIN WS1370 61 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 34557970 Common - hypothetical protein WS1654 2 None None None 34557200 Common - hypothetical protein WS0802 7 None None None 34557762 Common - hypothetical protein WS1413 11 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 34556958 Common tlpA hypothetical protein WS0538 5 None None None 34557979 Common fliE flagellar hook-basal body protein FliE WS1664 43 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 34557909 Nonpathogen - hypothetical protein WS1584 1 None None None 34557304 Common NOSZ NITROUS OXIDE REDUCTASE SUBUNIT WS0914 39 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 34558068 Common - hypothetical protein WS1761 4 None None None 34558098 Common - conserved hypothetical protein-Xanthosine triphosphate pyrophosphatase WS1795 233 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 34558151 Common CYDA CYTOCHROME BD OXIDASE SUBUNIT I WS1853 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 34558018 Common rplN 50S ribosomal protein L14 WS1706 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 34556991 Common hisS hypothetical protein WS0572 9 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 34557408 Common TNPA PUTATIVE TRANSPOSASE WS1022 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34558209 Common - conserved hypothetical protein-SAM dependent methyltransferase WS1915 48 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 34557843 Common - PEPTIDASE-Di-tripeptidase WS1509 54 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 34557075 Common ansB PERIPLASMIC L-ASPARAGINASE II WS0660 133 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 34556987 Common - PUTATIVE PERMEASE OF ABC TRANSPORTER WS0568 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 34557194 Common hypA hydrogenase nickel incorporation protein WS0796 55 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 34556692 Common - PUTATIVE LIPOPOLYSACCHARIDE BIOSYNTHESIS PROTEIN WS0252 226 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 34557637 Common NADC nicotinate-nucleotide pyrophosphorylase WS1273 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 34556840 Common CZCB2 CATION EFFLUX SYSTEM (CZCB-LIKE) WS0411 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 34556798 Common gyrA DNA gyrase subunit A WS0365 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 34557003 Common RIBF bifunctional riboflavin kinase/FMN adenylyltransferase WS0586 207 COG0196 RibF, FAD synthase Coenzyme metabolism 34558144 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS1845 100 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34558229 Common - SULFATE ADENYLYLTRANSFERASE WS1938 52 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 34557693 Common - hypothetical protein WS1335 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 34556791 Common ubiA prenyltransferase WS0357 129 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 34557136 Common - hypothetical protein WS0731 13 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 34557142 Common - HYDROXY-DEHYDRATASE ACTIVATOR WS0738 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 34558374 Common - MOTILITY PROTEIN A-FLAGELLAR MOTOR COMPONENT WS2090 104 COG1291 MotA, Flagellar motor component Cell motility and secretion 34558020 Common rplP 50S ribosomal protein L16 WS1709 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 34558302 Common - homoserine kinase WS2015 117 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 34557234 Common FDHD formate dehydrogenase accessory protein WS0838 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 34558183 Nonpathogen - hypothetical protein WS1888 1 None None None 34557950 Common - CYCLOPHILIN-TYPE PEPTIDYL-PROLYL ISOMERASE WS1634 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 34557083 Common - hypothetical protein WS0670 154 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 34557571 Common - GLUTAMATE SYNTHASE, LARGE SUBUNIT WS1202 204 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 34556709 Common - hypothetical protein WS0271 26 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 34556747 Common - tryptophanyl-tRNA synthetase WS0311 237 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34558280 Nonpathogen - hypothetical protein WS1993 1 None None None 34556625 Common FIXN CYTOCHROME OXIDASE (CBB3-TYPE) WS0178 154 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 34558316 Common - HYPOTHETICAL PROTEIN-PUTATIVE INTEGRASE WS2030 86 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 34557294 Common ARPC OUTER MEMBRANE CHANNEL PROTEIN WS0904 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 34558126 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase WS1826 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 34557333 Common pstS PHOSPHATE-BINDING PERIPLASMIC PROTEIN WS0944 99 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 34558222 Nonpathogen - hypothetical protein WS1928 2 None None None 34558250 Common UVRB excinuclease ABC subunit B WS1960 230 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 34557427 Common - hypothetical protein WS1042 2 None None None 34557450 Common oorD 2-oxoglutarate-acceptor oxidoreductase subunit OorD WS1067 60 COG1146 COG1146, Ferredoxin Energy production and conversion 34557714 Common TNPA PUTATIVE TRANSPOSASE WS1361 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557622 Common secA preprotein translocase subunit SecA WS1258 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 34557210 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase WS0812 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 34556544 Common - hypothetical protein WS0091 62 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 34556551 Common - LIN0826 PROTEIN WS0099 89 COG0679 COG0679, Predicted permeases General function prediction only 34558285 Common fliG flagellar motor switch protein G WS1998 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 34558467 Common CAPI CAPSULAR POLYSACCHARIDE SYNTHESIS ENZYME CAP5I WS2191 19 None None None 34557284 Common PURD phosphoribosylamine--glycine ligase WS0894 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 34557105 Common - hypothetical protein WS0694 13 None None None 34557026 Common flgA flagellar basal body P-ring biosynthesis protein FlgA WS0610 3 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 34557457 Common FLA FLAGELLIN WS1075 93 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 34556660 Common metG methionyl-tRNA synthetase WS0217 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557590 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR WS1224 89 COG1309 AcrR, Transcriptional regulator Transcription 34556891 Common rplL 50S ribosomal protein L7/L12 WS0466 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 34558205 Common - FERREDOXIN WS1911 148 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 34556847 Common pcm protein-L-isoaspartate O-methyltransferase WS0418 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 34557418 Common - hypothetical protein WS1033 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 34557916 Common flgI flagellar basal body P-ring protein WS1592 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 34557125 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0715 130 COG0679 COG0679, Predicted permeases General function prediction only 34557550 Common - hypothetical protein WS1180 16 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 34558149 Common - SIGNAL TRANSDUCTION RESPONSE REGULATOR-CheY like receiver and GGDEF domain WS1851 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34556852 Common FABI enoyl-(acyl carrier protein) reductase WS0423 231 COG0623 FabI, Enoyl- acyl-carrier-protein 34557077 Common aspA aspartate ammonia-lyase WS0662 235 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 34557597 Nonpathogen - hypothetical protein WS1231 3 None None None 34557607 Common FOLC FOLYLPOLYGLUTAMATE SYNTHASE WS1242 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 34558356 Common - REGULATORY PROTEIN DNIR WS2072 148 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 34556566 Common fdhA THIOSULFATE REDUCTASE .-.- WS0116 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34557085 Nonpathogen - hypothetical protein WS0672 1 None None None 34556957 Nonpathogen - hypothetical protein WS0537 1 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 34556623 Common - hypothetical protein WS0175 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 34556470 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0011 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34558059 Common - hypothetical protein WS1752 4 None None None 34557185 Common DAPD PUTATIVE SUCCINYL-TRANSFERASE WS0786 56 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 34557575 Common RHPR RESPONSE REGULATOR OF TWO-COMPONENT SYSTEM WS1208 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34558027 Common rplC 50S ribosomal protein L3 WS1716 216 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 34557371 Common - hypothetical protein WS0983 6 None None None 34557306 Common NOSZ NOSZ PROTEIN WS0916 47 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 34557260 Common - hypothetical protein WS0866 4 None None None 34557654 Common - hypothetical protein WS1291 22 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 34558381 Common - hypothetical protein WS2098 26 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 34557113 Common - SERINE/THREONINE PROTEIN PHOSPHATASE WS0702 89 None None None 34558455 Common - hypothetical protein WS2179 42 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 34558297 Common - hypothetical protein WS2010 78 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 34556463 Common - hypothetical protein WS0004 158 COG0344 COG0344, Predicted membrane protein Function unknown 34557103 Common - hypothetical protein WS0692 34 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 34556837 Common - hypothetical protein WS0408 148 COG0679 COG0679, Predicted permeases General function prediction only 34558492 Common PYRD dihydroorotate dehydrogenase 2 WS2219 233 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 34557875 Nonpathogen - hypothetical protein WS1547 10 None None None 34556491 Common - hypothetical protein WS0033 129 COG0456 RimI, Acetyltransferases General function prediction only 34557327 Common TTRA TTRA WS0938 79 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34557277 Nonpathogen bacA hypothetical protein WS0887 1 None None None 34557059 Common - hypothetical protein WS0643 62 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 34557788 Common - hypothetical protein WS1443 20 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 34556830 Common - hypothetical protein WS0399 20 COG3787 COG3787, Uncharacterized protein conserved in bacteria Function unknown 34556809 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0376 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 34556672 Common - hypothetical protein WS0230 9 COG3608 COG3608, Predicted deacylase General function prediction only 34556650 Common CADF CADF PRECURSOR WS0207 170 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 34556864 Common - 2-HYDROXY-6-OXOHEPTA-2,4-DIENOATE HYDROLASE WS0437 124 COG1254 AcyP, Acylphosphatases Energy production and conversion 34556936 Common ATPA F0F1 ATP synthase subunit alpha WS0514 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 34556636 Common - PUTATIVE ENDONUCLEASE WS0190 48 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 34558008 Common infA translation initiation factor IF-1 WS1696 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 34558400 Common - hypothetical protein WS2117 107 COG0327 COG0327, Uncharacterized conserved protein Function unknown 34556686 Common - hypothetical protein WS0245 13 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 34556966 Common FFH SIGNAL RECOGNITION PARTICLE PROTEIN WS0547 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 34558441 Common ARGG argininosuccinate synthase WS2164 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 34558416 Common - hypothetical protein WS2134 87 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 34556592 Common - PUTATIVE FIBRONECTIN DOMAIN-CONTAINING LIPOPROTEIN WS0144 21 COG3401 COG3401, Fibronectin type 3 domain-containing protein General function prediction only 34558046 Common htpG heat shock protein 90 WS1737 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 34556842 Common - hypothetical protein WS0413 71 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 34557534 Nonpathogen - hypothetical protein WS1162 1 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 34557886 Common - THIOREDOXIN WS1558 122 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 34558139 Common hyfE hydrogenase 4 membrane subunit WS1840 35 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 34557354 Nonpathogen - hypothetical protein WS0966 1 None None None 34557667 Common - HIT-FAMILY PROTEIN WS1306 219 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 34556875 Common - hypothetical protein WS0448 6 None None None 34558045 Nonpathogen rpoN hypothetical protein WS1735 1 None None None 34557177 Common - hypothetical protein WS0777 3 None None None 34556932 Common - STAGE 0 SPORULATION PROTEIN J WS0510 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 34558051 Common - potassium/proton antiporter WS1742 132 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 34557580 Common - PROTEIN-GLUTAMATE METHYLESTERASE WS1213 151 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 34557681 Common - hypothetical protein WS1320 86 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 34556599 Common fliS flagellar protein FliS WS0151 81 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 34556825 Common - hypothetical protein WS0394 74 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 34557267 Common - PUTATIVE TRANSMEMBRANE PROTEIN WS0873 5 None None None 34556804 Common - hypothetical protein WS0371 68 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 34556553 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase WS0101 154 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 34557346 Common - hypothetical protein WS0958 3 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 34558172 Common clpA PHOSPHOENOLPYRUVATE CARBOXYLASE PEPCASE PEPC WS1877 119 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 34556680 Common - DNA-directed RNA polymerase subunit omega WS0239 6 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 34557985 Common - MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN WS1672 127 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557523 Common - hypothetical protein WS1151 6 None None None 34557925 Common - ASPARTATE OXIDASE WS1604 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 34557118 Common - MOLYBDOPTERIN OXIDOREDUCTASE, IRON-SULFUR BINDING SUBUNIT WS0708 168 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34556889 Common rplA 50S ribosomal protein L1 WS0464 236 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 34556882 Common dapB dihydrodipicolinate reductase WS0455 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 34557619 Nonpathogen - hypothetical protein WS1255 1 None None None 34557245 Common - TWO-COMPONENT HYBRID SENSOR AND REGULATOR WS0849 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34558165 Common MODD MOLYBDENUM TRANSPORT SYSTEM PROTEIN WS1870 189 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 34556754 Common ATPB F0F1 ATP synthase subunit A WS0318 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 34557032 Common - hypothetical protein WS0616 14 None None None 34558289 Common PYRC dihydroorotase WS2002 86 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 34557798 Common - PUTATIVE ISOCITRATE DEHYDROGENASE WS1454 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 34557960 Common PEPQ PROLINE AMINOPEPTIDASE WS1644 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 34556589 Common pstA PUTATIVE NA+-DEPENDENT TRANSPORTER WS0141 91 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 34557670 Common - 3-phosphoshikimate 1-carboxyvinyltransferase WS1309 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 34557868 Common - 3-POLYPRENYL-4HYDROXYBENZOATE DECARBOXYLASE WS1540 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 34558394 Common LGT prolipoprotein diacylglyceryl transferase WS2111 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 34557913 Common NAPA NEUTROPHIL-ACTIVATING PROTEIN (NEUTROPHIL ACTIVATING PROTEIN NAPA)(FRAGMENT) WS1589 127 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 34558211 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase WS1917 139 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 34556899 Common NUOC NADH dehydrogenase subunit C WS0474 171 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 34558115 Common - hypothetical protein WS1814 4 None None None 34558426 Common carB carbamoyl phosphate synthase large subunit WS2147 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 34557552 Common - hypothetical protein WS1182 7 COG2863 COG2863, Cytochrome c553 Energy production and conversion 34557051 Common mviN SIMILARITY TO mviN PROTEIN WS0635 48 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 34556501 Common glmS GALACTOSYL TRANSFERASE, GDP-MANNOSE PYROPHOSPHORYLASE,PHOSPHOMANNOMUTASE, UDP-GALACTOSE 4-EPIMERASE, GALACTOSYL TRANSFERASE,NUCLEOTIDE SUGAR DEHYDROGENASE, NUCLEOTIDE SUGAR EPIMERASE, ANDPUTATIVE EPIMERASE/DEHYDRATASE GENES; AND UNKNOWN GENES WS0046 161 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 34557675 Nonpathogen - hypothetical protein WS1314 1 None None None 34557412 Common GAP_2 glyceraldehyde-3-phosphate dehydrogenase WS1026 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 34557986 Common - SIGNAL-TRANSDUCTION SENSOR PROTEIN-PAS/PAC domain WS1673 90 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 34558366 Common - PURINE-BINDING CHEMOTAXIS PROTEIN CHEW WS2082 135 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 34557066 Common - hypothetical protein WS0650 48 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 34557139 Common FDHB FORMATE DEHYDROGENASE SUBUNIT WS0735 181 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34557549 Common - hypothetical protein WS1179 149 COG0730 COG0730, Predicted permeases General function prediction only 34556913 Common PFLA FLAGELLAR FUNCTIONAL PROTEIN WS0490 6 None None None 34556607 Common - hypothetical protein WS0159 7 None None None 34557677 Common - ABC TRANSPORTER WS1316 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 34557013 Common - DNA polymerase III subunit epsilon WS0596 114 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 34557258 Common - PUTATIVE MCP-TYPE SIGNAL TRANSDUCTION PROTEIN WS0864 138 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557419 Common - PUTATIVE TWO-COMPONENT SENSOR WS1034 196 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34557737 Nonpathogen - hypothetical protein WS1385 13 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 34557565 Common MOAD hypothetical protein WS1196 7 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 34557512 Common - hypothetical protein WS1139 10 COG1993 COG1993, Uncharacterized conserved protein Function unknown 34557542 Common napD HYPOTHETICAL PROTEIN , NapD domain WS1170 7 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 34557732 Nonpathogen - hypothetical protein WS1380 1 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 34557378 Common VCA1001 TRANSCRIPTIONAL REGULATOR, ARAC/XYLS FAMILY WS0990 94 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 34556924 Common - TRANSLATION INITIATION INHIBITOR WS0502 195 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 161760545 Common trmE tRNA modification GTPase TrmE WS1284 229 COG0486 ThdF, Predicted GTPase General function prediction only 34557426 Common - hypothetical protein WS1041 2 None None None 34558409 Common - S-ribosylhomocysteinase WS2126 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 34558195 Common - hypothetical protein WS1901 7 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 34557464 Nonpathogen - hypothetical protein WS1083 1 None None None 34556732 Common nusB transcription antitermination protein NusB WS0296 189 COG0781 NusB, Transcription termination factor Transcription 34557969 Common - URACIL PHOSPHORIBOSYLTRANSFERASE WS1653 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 34558474 Common - hypothetical protein WS2199 18 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 34556901 Common NUOE PUTATIVE NADH OXIDOREDUCTASE I WS0476 6 None None None 34557338 Common - MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN WS0949 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34558309 Common - ABC TRANSPORTER, ATP-BINDING PROTEIN WS2022 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 34558313 Nonpathogen - hypothetical protein WS2027 1 None None None 34558218 Common gdhA glutamate dehydrogenase WS1924 169 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 34558179 Common - Holliday junction resolvase-like protein WS1884 7 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 34557236 Common selA selenocysteine synthase WS0840 69 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 34557625 Common - hypothetical protein WS1261 109 COG0824 FcbC, Predicted thioesterase General function prediction only 34556890 Common rplJ 50S ribosomal protein L10 WS0465 209 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 34557268 Common LYSR1 TRANSCRIPTIONAL REGULATOR (LYSR FAMILY) WS0874 183 COG0583 LysR, Transcriptional regulator Transcription 34556826 Common glnH ALDEHYDE OXIDOREDUCTASE WS0395 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 34557192 Common - hypothetical protein WS0794 9 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 34556996 Common FDXI hypothetical protein WS0579 33 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 34556721 Common - hypothetical protein WS0285 26 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34558155 Common - hypothetical protein WS1858 8 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 34557379 Nonpathogen - hypothetical protein WS0991 1 None None None 34557285 Common - hypothetical protein WS0895 7 COG1714 COG1714, Predicted membrane protein/domain Function unknown 34557168 Common - Transcription Regulator Protein WS0767 97 COG1309 AcrR, Transcriptional regulator Transcription 34557882 Common - hypothetical protein WS1554 68 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 34558252 Common PRIA primosome assembly protein PriA WS1964 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 34558002 Common - conserved hypothetical protein-Thioredoxin-like proteins and domains WS1690 101 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 34557161 Common - PUTATIVE ARSENATE REDUCTASE WS0760 129 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 34558062 Common - hypothetical protein WS1755 6 None None None 34556514 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase WS0060 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 34556498 Common WBPS WBPS WS0042 149 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 34557503 Common - hypothetical protein WS1128 22 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 34557764 Common HUGA HUGA WS1416 74 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 34557008 Common chuA OUTER MEMBRANE RECEPTOR FOR FE(III)-COPROGEN WS0591 101 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 34557394 Nonpathogen - hypothetical protein WS1007 3 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 34557567 Common - PUTATIVE ATP/GTP BINDING PROTEIN WS1198 48 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 34556483 Common WCFX PUTATIVE UDP-GLUCURONIC ACID EPIMERASE WS0025 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 34556698 Common - hypothetical protein WS0258 22 None None None 34558259 Common acpS 4'-phosphopantetheinyl transferase WS1971 134 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 34557751 Nonpathogen - hypothetical protein WS1400 4 COG5554 NifU, Nitrogen fixation protein Secondary metabolites biosynthesis, transport, and catabolism 34557028 Common coaD phosphopantetheine adenylyltransferase WS0612 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 34558393 Common THRC threonine synthase WS2110 133 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 34558016 Common rplE 50S ribosomal protein L5 WS1704 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 34558340 Common - hypothetical protein WS2055 4 None None None 34557403 Common - hypothetical protein WS1016 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 34557726 Common - NON-HAEM IRON PROTEIN WS1374 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 34556773 Common aat leucyl/phenylalanyl-tRNA--protein transferase WS0338 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 34557130 Common - PROTON/GLUTAMATE SYMPORTER WS0722 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 34558486 Common def peptide deformylase WS2212 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 34557116 Nonpathogen - hypothetical protein WS0706 1 COG2863 COG2863, Cytochrome c553 Energy production and conversion 34557977 Common fliD hypothetical protein WS1662 5 None None None 34556981 Common - hypothetical protein WS0562 13 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 34557720 Common - PUTATIVE ATP /GTP BINDING PROTEIN WS1367 47 COG1159 Era, GTPase General function prediction only 34558095 Common ligA NAD-dependent DNA ligase LigA WS1790 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 34556816 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0384 69 COG1981 COG1981, Predicted membrane protein Function unknown 34556919 Common - heat-inducible transcription repressor WS0496 135 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 34557845 Common - hypothetical protein WS1512 11 None None None 34556641 Common BCP BACTERIOFERRITIN COMIGRATORY PROTEIN WS0196 225 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 34558326 Nonpathogen - hypothetical protein WS2041 1 None None None 34557867 Common - HYPOTHETICAL PROTEIN-Methylated DNA-protein cysteine methyltransferase WS1539 180 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 34556694 Common WAAQ PUTATIVE HEPTOSYLIII TRANSFERASE WS0254 88 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 34558030 Common - hypothetical protein WS1719 3 None None None 34557929 Common PDT RECEPTOR PRECURSOR-Mostly Fe transport WS1610 125 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 34557336 Common PSTC PHOSPHATE TRANSPORT PERMEASE WS0947 223 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 34558447 Common - PUTATIVE CATION-TRANSPORTING ATPASE WS2171 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 34557355 Common NRFJ NRFJ WS0967 9 None None None 34556600 Nonpathogen - hypothetical protein WS0152 1 None None None 34557705 Common - hypothetical protein WS1349 4 None None None 34557073 Common RHPS TWO COMPONENT SENSOR KINASE WS0658 194 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 34558372 Common - PUTATIVE TWO-COMPONENT REGULATOR WS2088 223 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 34557039 Common PSSA PHOSPHATIDYLTRANSFERASE WS0623 153 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 34557144 Common TRP1400B PUTATIVE TRANSPOSASE WS0741 117 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557223 Common purL phosphoribosylformylglycinamidine synthase II WS0827 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 34557653 Common BACA PUTATIVE UNDECAPRENOL KINASE BACITRACIN RESISTANCE PROTEIN WS1290 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 34557479 Nonpathogen - hypothetical protein WS1101 1 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 34556570 Common RHPS SENSOR KINASE OF TWO-COMPONENT REGULATORY SYSTEM WS0120 168 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34558334 Common - PENICILLIN-BINDING PROTEIN 1A PBP-1A WS2049 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 34557296 Common - hypothetical protein WS0906 50 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 34558427 Common speE spermidine synthase WS2148 35 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 34556578 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0129 29 COG2056 COG2056, Predicted permease General function prediction only 34556703 Common - hypothetical protein WS0264 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 34556465 Common - PUTATIVE CHOLINE TRANSPORTER WS0006 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 34557098 Common - PUTATIVE RADICAL-ACTIVATING ENZYME WS0687 62 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 34557386 Common - hypothetical protein WS0998 3 None None None 34557636 Common THIL thiamine monophosphate kinase WS1272 181 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 34557018 Common - hypothetical protein WS0602 46 COG4327 COG4327, Predicted membrane protein Function unknown 34557660 Common - hypothetical protein WS1298 146 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 34558469 Common - hypothetical protein WS2193 32 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 34557522 Common - hypothetical protein WS1150 37 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 34556769 Nonpathogen - hypothetical protein WS0334 2 None None None 34558086 Common - hypothetical protein WS1779 3 None None None 34556841 Common ACRD ACRIFLAVIN RESISTANCE PROTEIN D WS0412 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 34557107 Common - PUTATIVE SIGNAL-TRANSDUCTION SENSOR PROTEIN WS0696 92 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 34558073 Common - fumarate hydratase WS1766 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 34556978 Common - 3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUBUNIT WS0559 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 34556947 Common NIFR1 hypothetical protein WS0526 10 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 34556689 Nonpathogen - hypothetical protein WS0249 1 None None None 34556536 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0083 9 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 34556568 Common NRFD NRFD WS0118 21 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 34557127 Common trpB tryptophan synthase subunit beta WS0719 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 34557851 Common - hypothetical protein WS1518 10 COG3400 COG3400, Uncharacterized protein conserved in bacteria Function unknown 34558227 Nonpathogen - hypothetical protein WS1936 1 None None None 34557599 Common - S-METHYLTRANSFERASE WS1234 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 34558325 Common engA GTP-binding protein EngA WS2040 238 COG1160 COG1160, Predicted GTPases General function prediction only 34558220 Common YDAA HYPOTHETICAL PROTEIN-Putative Site-specific recombinase WS1926 120 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 34556794 Common - hypothetical protein WS0361 104 COG1738 COG1738, Uncharacterized conserved protein Function unknown 34557858 Common - HYPOTHETICAL PROTEIN-HEMERYTHRIN WS1527 47 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 34558476 Common - TRANSCRIPTIONAL REGULATOR (PHOB-LIKE) WS2201 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557776 Common DMSA DMSA WS1430 179 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34556481 Common - hypothetical protein WS0023 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34557207 Common MURI glutamate racemase WS0809 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 34557839 Common FLAG flagellin WS1503 115 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 34557816 Common - PROTEASE IV (PSPA) WS1476 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 34558247 Common TNPA PUTATIVE TRANSPOSASE WS1957 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557474 Common COMB2 COMB2 WS1095 16 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 34558460 Common - hypothetical protein WS2184 21 COG1817 COG1817, Uncharacterized protein conserved in archaea Function unknown 34557900 Common rfaJ ALR4513 PROTEIN WS1575 9 COG4902 COG4902, Uncharacterized protein conserved in archaea Function unknown 34557246 Common - SENSORY TRANSDUCTION HISTIDINE KINASE WS0850 231 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34558418 Common rplM 50S ribosomal protein L13 WS2138 227 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 34557691 Common - hypothetical protein WS1332 3 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 34558177 Common - hypothetical protein WS1882 21 COG2319 COG2319, FOG: WD40 repeat General function prediction only 34558210 Common - METHYL ACCEPTING CHEMOTAXIS PROTEIN WS1916 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556603 Common - DKSA-LIKE PROTEIN WS0155 156 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 34557365 Common dppF OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN APPF WS0977 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 34557068 Common moaD hypothetical protein WS0652 2 None None None 34558238 Common - HYPOTHETICAL PROTEIN-Predicted membrane protein WS1947 128 COG2860 COG2860, Predicted membrane protein Function unknown 34558001 Common - hypothetical protein WS1689 7 None None None 34556522 Common INT hypothetical protein WS0068 2 None None None 34557468 Nonpathogen - hypothetical protein WS1088 1 None None None 34558368 Common CHEV CHEMOTAXIS PROTEIN WS2084 151 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 34557037 Common FTSH ZINC METALLOPEPTIDASE WS0621 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 34558074 Common - FUMARATE HYDRATASE B, BETA SUBUNIT WS1767 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 34557570 Common gltD glutamate synthase subunit beta WS1201 197 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 34556786 Common - PUTATIVE PROCESSING PROTEASE WS0352 129 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 34557016 Common secY hypothetical protein WS0599 49 COG3162 COG3162, Predicted membrane protein Function unknown 34556896 Common - PUTATIVE HISTIDINOL PHOSPHATASE WS0471 38 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 34557739 Common NIFX NIFX WS1387 32 None None None 34557518 Common FDHA FORMATE DEHYDROGENASE LARGE SUBUNIT PRECURSOR WS1146 191 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 34557585 Common - hypothetical protein WS1219 12 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 34556646 Common dctA URACIL PERMEASE WS0203 121 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 34556549 Common FTSK SEPTUM FORMATION PROTEIN WS0096 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 34556524 Common PAB1098 hypothetical protein WS0070 144 COG0456 RimI, Acetyltransferases General function prediction only 34557716 Nonpathogen - hypothetical protein WS1363 1 None None None 34557257 Nonpathogen - hypothetical protein WS0863 1 None None None 34557373 Common NIKB NICKEL TRANSPORT SYSTEM PERMEASE WS0985 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 34558480 Common - NIFU-LIKE PROTEIN WS2205 117 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 34558164 Common - CHEMOTAXIS PROTEIN CHEV-CheY like receiver domain WS1869 133 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 34557683 Common - hypothetical protein WS1322 131 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 34558193 Common rnc ribonuclease III WS1899 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 34558305 Common - hypothetical protein WS2018 156 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 34558150 Common CYDB CYTOCHROME BD OXIDASE SUBUNIT II WS1852 138 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 34558380 Common - ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE WS2097 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 34557612 Common secF preprotein translocase subunit SecF WS1247 217 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 34557462 Common CHEA hypothetical protein WS1080 118 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 34556542 Nonpathogen - hypothetical protein WS0089 1 None None None 34557988 Common - HYDROLASE-Predicted amidohydrolase WS1675 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 34557557 Common - CYSTEINE SYNTHASE/CYSTATHIONINE BETA-SYNTHASE WS1188 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 34557930 Common - HYPOTHETICAL PROTEIN-Predicted flavin-nucleotide-binding WS1611 40 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 34557807 Common - SIGNAL-TRANSDUCING PROTEIN, HISTIDINE KINASE WS1464 89 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 34556735 Common - DEOXYGUANOSINE TRIPHOSPHATE TRIPHOSPHOHYDROLASE WS0299 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 34556856 Nonpathogen - hypothetical protein WS0428 1 None None None 34557151 Nonpathogen - hypothetical protein WS0750 3 None None None 34557702 Common LEPP SIGNAL PEPTIDASE I WS1346 180 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 34558292 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B WS2005 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 34557642 Common thiJ MONOPHOSPHATE SYNTHESISPROTEIN WS1278 92 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 34558406 Common - hypothetical protein WS2123 5 None None None 34557540 Common - hypothetical protein WS1168 149 COG1733 COG1733, Predicted transcriptional regulators Transcription 34558421 Common - hypothetical protein WS2141 48 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 34557087 Common - TYPE IV PREPILIN PEPTIDASE WS0674 121 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 34557707 Common - tryptophan synthase subunit beta WS1351 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 34557030 Common - hypothetical protein WS0614 7 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 34556776 Common - hypothetical protein WS0341 2 None None None 34557826 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase WS1488 149 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 34558010 Common secY preprotein translocase subunit SecY WS1698 237 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 34557270 Nonpathogen ileS hypothetical protein WS0877 1 None None None 34557760 Common - hypothetical protein WS1411 5 None None None 34558489 Common - hypothetical protein WS2216 117 COG2353 COG2353, Uncharacterized conserved protein Function unknown 34557800 Nonpathogen - hypothetical protein WS1456 1 None None None 34557197 Common greA transcription elongation factor GreA WS0799 204 COG0782 GreA, Transcription elongation factor Transcription 34557511 Common ccrB camphor resistance protein CrcB WS1138 45 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 34556629 Nonpathogen - hypothetical protein WS0182 1 None None None 34556767 Common PHEA CHORISMATE MUTASE\PREPHENATE DEHYDRATASE WS0332 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 34557050 Common - FERREDOXIN DOMAIN INTEGRAL MEMBRANE WS0634 91 COG0348 NapH, Polyferredoxin Energy production and conversion 34556884 Common AQ_632 hypothetical protein WS0457 98 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 34558039 Common LYSC aspartate kinase WS1729 237 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 34557611 Common - hypothetical protein WS1246 7 None None None 34556952 Nonpathogen - hypothetical protein WS0531 2 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 34558497 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS2224 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 34556928 Common PROB gamma-glutamyl kinase WS0506 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 34557821 Common - ATP-DEPENDENT RNA HELICASE, DEAD-BOX FAMILY DEAD WS1482 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 34556590 Common MRDB RODA PROTEIN HOMOLOG WS0142 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 34556581 Common ILVA threonine dehydratase WS0132 230 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 34557445 Common - hypothetical protein WS1062 10 None None None 34556970 Common trmD tRNA (guanine-N(1)-)-methyltransferase WS0551 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 34556905 Common - NADH-UBIQUINONE OXIDOREDUCTASE, NQO3 SUBUNIT NQO3 WS0480 6 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 34558103 Common - FLAGELLAR BASAL-BODY ROD PROTEIN FLGG WS1801 124 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 34557753 Common clpX ATP-dependent protease ATP-binding subunit WS1403 224 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 34558041 Common - DNA polymerase III subunit delta' WS1731 7 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 34557669 Common pheT phenylalanyl-tRNA synthetase subunit beta WS1308 224 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 34557963 Common - FLAVOPROTEIN WS1647 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 34558133 Common - hypothetical protein WS1834 25 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 34557996 Common HYAD HYDROGENASE EXPRESSION/FORMATION PROTEIN WS1684 63 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 34558050 Common - PREDICTED PEMEASE WS1741 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 34556873 Common - hypothetical protein WS0446 209 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 34557879 Common oppB hypothetical protein WS1551 35 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 34556476 Common - hypothetical protein WS0017 146 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 34557884 Common DGC2 DIGUANYLATE CYCLASE WS1556 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 34557311 Common - hypothetical protein WS0922 7 COG2863 COG2863, Cytochrome c553 Energy production and conversion 34557080 Common - hypothetical protein WS0667 2 None None None 34557539 Common CAC2934 PREDICTED TRANSCRIPTIONAL REGULATOR WS1167 141 COG1733 COG1733, Predicted transcriptional regulators Transcription 34556714 Common - AMINO ACID PERMEASE ATP-BINDING PROTEIN WS0277 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 34556597 Common - flagellar protein FlaG WS0149 12 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 34556854 Common - hypothetical protein WS0426 31 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 34558387 Common - hypothetical protein WS2104 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 34556960 Nonpathogen - hypothetical protein WS0540 1 None None None 34557582 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS1216 97 COG1981 COG1981, Predicted membrane protein Function unknown 34556726 Common - PROX PROTEIN WS0290 26 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 34556552 Common - hypothetical protein WS0100 6 None None None 34557428 Common thrS hypothetical protein WS1043 91 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 34556468 Common CYTA CYTA PROTEIN PRECURSOR WS0009 35 COG3258 COG3258, Cytochrome c Energy production and conversion 34557430 Common ZURR hypothetical protein WS1045 23 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 34556748 Common - PUTATIVE METHYL TRANSFERASE WS0312 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 34557577 Common - hypothetical protein WS1210 70 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 34557749 Common - hypothetical protein WS1398 31 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 34556990 Nonpathogen purH hypothetical protein WS0571 1 None None None 34557935 Common - HYPOTHETICAL PROTEIN-RecB family exonuclease WS1617 18 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 34556657 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0214 180 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 34557279 Common - hypothetical protein WS0889 19 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 34558099 Common - HYPOTHETICAL PROTEIN-Signal transduction histidine kinase WS1796 31 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34557870 Common - hypothetical protein WS1542 29 COG2259 COG2259, Predicted membrane protein Function unknown 34556824 Common - hypothetical protein WS0393 5 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 34557302 Common - hypothetical protein WS0912 11 COG2319 COG2319, FOG: WD40 repeat General function prediction only 34557601 Common - hypothetical protein WS1236 109 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 34556741 Common - PUTATIVE TWO-COMPONENT SENSOR WS0305 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34558113 Common LEUD-1 3-ISOPROPYLMALATE DEHYDRATASE, SMALL SUBUNIT LEUD-1 WS1812 211 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 34558170 Common - RIBONUCLEASE WS1875 192 COG0557 VacB, Exoribonuclease R Transcription 34556959 Nonpathogen - hypothetical protein WS0539 1 None None None 34556630 Common - hypothetical protein WS0184 6 None None None 34558048 Common TNPA PUTATIVE TRANSPOSASE WS1739 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557898 Common - hypothetical protein WS1573 2 None None None 34557771 Nonpathogen - hypothetical protein WS1424 1 None None None 34557525 Nonpathogen - hypothetical protein WS1153 1 None None None 34557331 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0942 75 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 34557305 Common TNPA PUTATIVE TRANSPOSASE WS0915 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557053 Common - hypothetical protein WS0637 9 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 34557437 Common flhA flagellar biosynthesis protein A WS1053 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 34556861 Common - hypothetical protein WS0434 20 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 34557071 Common - hypothetical protein WS0656 131 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 34557300 Common - hypothetical protein WS0910 31 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 34556885 Common - hypothetical protein WS0458 61 COG4121 COG4121, Uncharacterized conserved protein Function unknown 34557109 Common dnaJ CHAPERONE WITH DNAK, HEAT SHOCK PROTEIN DNAJ PROTEIN WS0698 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 34557975 Common - AAA FAMILY ATPASE WS1660 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 34557724 Common - PUTATIVE ABC-TRANSPORT SYSTEM ATP-BINDING PROTEIN WS1372 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 34556701 Nonpathogen - hypothetical protein WS0261 1 None None None 34557048 Common rpsU 30S ribosomal protein S21 WS0632 7 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 34557261 Common gidB glucose-inhibited division protein B WS0867 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 34558225 Common TRP1400B PUTATIVE TRANSPOSASE WS1931 132 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557159 Nonpathogen - hypothetical protein WS0758 6 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 34557865 Common - conserved hypothetical protein-Zn-dependent protease with chaperone function WS1536 122 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 34557981 Common flgB flagellar basal body rod protein FlgB WS1667 88 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 34558119 Common - RNA NUCLEOTIDYLTRANSFERASE WS1819 211 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 34556775 Common GALU UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE WS0340 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 34557309 Common NAPG IRON-SULFUR PROTEIN WS0920 41 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 34557805 Common - hypothetical protein WS1462 47 COG3150 COG3150, Predicted esterase General function prediction only 34558121 Common HEMB delta-aminolevulinic acid dehydratase WS1821 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 34557241 Common - hypothetical protein WS0845 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 34556994 Common - hypothetical protein WS0575 6 None None None 34557651 Common - hypothetical protein WS1287 134 COG0759 COG0759, Uncharacterized conserved protein Function unknown 34556983 Common - hypothetical protein WS0564 18 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 34557530 Common - hypothetical protein WS1158 22 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 34557132 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0725 18 COG2510 COG2510, Predicted membrane protein Function unknown 34557343 Common - hypothetical protein WS0955 4 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 34557362 Common - TWO-COMPONENT HYBRID PROTEIN WS0974 225 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 34557431 Common - ADHESION PROTEIN WS1046 168 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 34558153 Common - hypothetical protein WS1855 4 COG1433 COG1433, Uncharacterized conserved protein Function unknown 34556705 Common - hypothetical protein WS0266 7 None None None 34556722 Common - hypothetical protein WS0286 23 COG3461 COG3461, Uncharacterized conserved protein Function unknown 34557954 Common fliM flagellar motor switch protein FliM WS1638 107 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 34558462 Common WLBC WLBC PROTEIN WS2186 207 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 34557205 Nonpathogen czcA hypothetical protein WS0807 1 None None None 34558191 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A WS1896 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 34557384 Common - hypothetical protein WS0996 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 34557830 Common recA recombinase A WS1493 220 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 34558478 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR (LYSR FAMILY) WS2203 185 COG0583 LysR, Transcriptional regulator Transcription 34556485 Common FDHC FORMATE DEHYDROGENASE SUBUNIT C PRECURSOR WS0027 68 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 34557092 Common GMHD GLYCERO-MANNOHEPTOSE-EPIMERASE WS0679 229 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 34557405 Nonpathogen - hypothetical protein WS1018 4 None None None 34558231 Common ispDF bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein WS1940 190 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 34558331 Common RHPS SENSOR KINASE OF TWO-COMPONENT REGULATORY SYSTEM WS2046 196 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34557166 Common HMOA MOLYBDOPTERIN OXIDOREDUCTASE WS0765 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34556938 Common ATPD F0F1 ATP synthase subunit beta WS0516 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 34556843 Common - hypothetical protein WS0414 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34557021 Common purQ phosphoribosylformylglycinamidine synthase subunit I WS0605 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 34557747 Common NIFV1 HOMOCITRATE SYTHASE 1 WS1396 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 34557414 Common ftsI PFK PROTEIN WS1028 153 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 34558201 Common - GLYCOSYLTRANSFERASE WS1907 109 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 34558281 Common metX S-adenosylmethionine synthetase WS1994 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 34557120 Common dnaJ hypothetical protein WS0710 3 None None None 34557496 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR WS1120 180 COG0640 ArsR, Predicted transcriptional regulators Transcription 34557501 Common PRRA TONB-DEPENDENT OUTER MEMBRANE RECEPTOR WS1126 127 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 34557627 Common chuA hypothetical protein WS1263 2 None None None 34558395 Nonpathogen - hypothetical protein WS2112 2 None None None 34557774 Common EXBD2 BIOPOLYMER TRANSPORT EXBD PROTEIN WS1427 126 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 34557932 Common - hypothetical protein WS1613 4 None None None 34556696 Common - MULTIDRUG RESISTANCE PROTEIN MSBA WS0256 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 34557559 Common - hypothetical protein WS1190 18 COG3945 COG3945, Uncharacterized conserved protein Function unknown 34558323 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase WS2038 224 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 34558276 Common - 3-oxoacyl-(acyl carrier protein) synthase III WS1988 230 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 34557348 Common HECB HECB PRECURSOR WS0960 58 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 34557818 Common - hypothetical protein WS1478 219 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 34557055 Common TETAJ hypothetical protein WS0639 9 None None None 34557269 Common - ATP-DEPENDENT DNA HELICASE WS0876 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 34557369 Common - OLIGOPEPTIDE ABC TRANSPORTER PERMEASE WS0981 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 34558296 Common flhB flagellar biosynthesis protein FlhB WS2009 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 34557856 Common - RESPONSE REGULATOR OMPR-CheY-like and winged-helix DNA-binding domain WS1523 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34556614 Common - CARBOXYNORSPERMIDINE DECARBOXYLASE (NSPC) WS0166 54 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 34557810 Common LIVG ABC TRANSPORT SYSTEM ATP-BINDING PROTEIN WS1467 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 34557823 Common murC UDP-N-acetylmuramate--L-alanine ligase WS1484 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 34557100 Common - para-aminobenzoate synthase component I WS0689 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 34558452 Common - hypothetical protein WS2176 135 COG2252 COG2252, Permeases General function prediction only 34558146 Common - HYPOTHETICAL PROTEIN-Putative Protein-disulfide isomerase WS1847 3 None None None 34557287 Common - hypothetical protein WS0897 67 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 34557221 Common rplT 50S ribosomal protein L20 WS0823 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 34557140 Common fdhC FORMATE DEHYDROGENASE PRECURSOR WS0736 68 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 34558245 Common - SIGNAL TRANSDUCTION HISTIDINE KINASE WS1955 88 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 34557837 Common BIOB biotin synthase WS1500 176 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 34557665 Common DGC3 DIGUANYLATE CYCLASE (FRAGMENT) WS1304 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 34558358 Nonpathogen - hypothetical protein WS2074 1 None None None 34557966 Common - ATP-DEPENDENT HELICASE WS1650 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 34556572 Common FCCB FLAVOCYTOCHROME C HEME SUBUNIT WS0122 6 None None None 34557784 Nonpathogen - hypothetical protein WS1439 1 None None None 34557312 Common NAPH NAPH WS0923 73 COG0348 NapH, Polyferredoxin Energy production and conversion 34557248 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0853 204 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557353 Common - GGDEF FAMILY PROTEIN WS0965 171 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34557215 Common rpsT 30S ribosomal protein S20 WS0817 191 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 34557220 Common rpmI 50S ribosomal protein L35 WS0822 98 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 34557840 Common - conserved hypothetical protein-TPR-repeat-containing WS1505 35 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 34558064 Common - hypothetical protein WS1757 15 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 34557099 Common - hypothetical protein WS0688 21 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 34558411 Common - ferrodoxin oxidoreductase beta subunit WS2128 129 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 34556812 Common - PEPTIDYL-PROLYL CIS-TRANS ISOMERASE WS0380 125 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 34556835 Nonpathogen - hypothetical protein WS0406 1 None None None 34556670 Nonpathogen - hypothetical protein WS0227 1 None None None 34558257 Common - ABC TRANSPORTER, PERMEASE PROTEIN WS1969 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 34556945 Common - hypothetical protein WS0523 17 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 34558412 Common porA pyruvate flavodoxin oxidoreductase subunit alpha WS2130 111 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 34556955 Nonpathogen - hypothetical protein WS0535 1 None None None 34556534 Common cute apolipoprotein N-acyltransferase WS0080 53 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 34558448 Common - ANTHRANILATE SYNTHASE COMPONENT II WS2172 241 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 34557527 Common YBFI YBFI PROTEIN WS1155 92 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 34558347 Common - PENICILLIN-BINDING PROTEIN WS2062 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 34557644 Common - fructose-bisphosphate aldolase WS1280 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 34556474 Common - hypothetical protein WS0015 19 None None None 34556561 Common TTG2A TOLUENE TOLERANCE PROTEIN TTG2A WS0110 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 34558092 Common NUON NADH DEHYDROGENASE SUBUNIT WS1785 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 34557147 Common - TRANSMEMBRANE TRANSPORT PROTEIN WS0746 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 34558351 Common - hypothetical protein WS2067 7 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 34558361 Common - conserved hypothetical protein-PREDICTED PEMEASE WS2077 17 COG0795 COG0795, Predicted permeases General function prediction only 34558404 Common PURE phosphoribosylaminoimidazole carboxylase catalytic subunit WS2121 231 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 34556778 Common thiF THIF, MOEB, HESA FAMILIY PROTEIN WS0343 150 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 34557199 Common - hypothetical protein WS0801 7 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 34556743 Common hemH hypothetical protein WS0307 49 COG2932 COG2932, Predicted transcriptional regulator Transcription 34556761 Common FIXS hypothetical protein WS0326 6 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 34556858 Common - hypothetical protein WS0431 12 None None None 34558423 Common - 2-hydroxyacid dehydrogenase WS2143 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 34556765 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein WS0330 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 34557847 Common - ATP-dependent Zn protease WS1514 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 34557157 Common - hypothetical protein WS0756 8 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 34557768 Common FAUA FERRIC ALCALIGIN SIDEROPHORE RECEPTOR WS1421 95 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 34557477 Common - VIRB4 HOMOLOG WS1099 55 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 34556845 Common PURB adenylosuccinate lyase WS0416 238 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 34558012 Common rpsE 30S ribosomal protein S5 WS1700 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 34558471 Common - hypothetical protein WS2196 2 None None None 34556642 Common cstA CONSERED HYPOTHETICAL PROTEIN WS0198 70 COG0398 COG0398, Uncharacterized conserved protein Function unknown 34556487 Common FDHA FORMATE DEHYDROGENASE PRECURSOR WS0029 191 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 34558107 Common - hypothetical protein WS1805 22 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 34556532 Common - PUTATIVE TWO-COMPONENT SENSOR WS0078 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34556917 Common dnaK molecular chaperone DnaK WS0494 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 34557272 Common csrA carbon storage regulator WS0879 44 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 34558215 Common SDHB SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN WS1921 200 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 34556898 Common NUOB NADH dehydrogenase subunit B WS0473 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 34558344 Common - hypothetical protein WS2059 3 None None None 34558332 Common - PUTATIVE TWO-COMPONENT REGULATOR WS2047 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557415 Common - hypothetical protein WS1029 148 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 34557671 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase WS1310 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 34557942 Common - conserved hypothetical protein-Molecular chaperones WS1625 5 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 34557965 Common - DNA METHYLASE-TYPE I RESTRICTION-MODIFICATION SYSTEM WS1649 111 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 34557383 Common - hypothetical protein WS0995 2 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 34556520 Common - hypothetical protein WS0066 165 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 34558278 Common - hypothetical protein WS1990 7 None None None 34558130 Common metE 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEI NE METHYLTRANSFERASE (METHIONINE SYNTHASE, VITAMIN-B12 INDEPENDENT ISOZYME)(COBALAMIN-INDEPENDENT METHIONINE SYNTHASE) WS1831 135 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 34557461 Nonpathogen - hypothetical protein WS1079 1 None None None 34557717 Common TNPA PUTATIVE TRANSPOSASE WS1364 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34558236 Common - ABC-TRANSPORT PERIPLASMIC PROTEIN WS1945 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 34557472 Nonpathogen - hypothetical protein WS1093 1 None None None 34557516 Common - hypothetical protein WS1144 11 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 34557828 Common - PUTATIVE CYTOCHROME C551 PEROXIDASE WS1491 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 34556736 Nonpathogen - hypothetical protein WS0300 3 None None None 34558294 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A WS2007 17 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 34557466 Common - hypothetical protein WS1085 13 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 34556479 Common - POSSIBLE NUCLEOTIDYLTRANSFERASE WS0021 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 34558180 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase WS1885 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 34557893 Common - hypothetical protein WS1567 9 None None None 34557733 Common RPON RNA polymerase factor sigma-54 WS1381 143 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 34556669 Common - hypothetical protein WS0226 116 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 34557255 Common - CELL DIVISION CYCLE PROTEIN 48-RELATED PROTEIN WS0861 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 34556539 Common - hypothetical protein WS0086 5 COG4951 COG4951, Uncharacterized protein conserved in bacteria Function unknown 34556547 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN II WS0094 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556685 Common - hypothetical protein WS0244 2 None None None 34557795 Common - hypothetical protein WS1451 6 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 34556620 Common - PUTATIVE OUTER MEMBRANE PROTEIN WS0172 6 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 34556920 Common - hypothetical protein WS0497 8 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 34556972 Common CYSE SERINE ACETYLTRANSFERASE WS0553 211 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 34557700 Common - hypothetical protein WS1344 7 None None None 34558187 Common - hypothetical protein WS1892 7 None None None 34556998 Common metE hypothetical protein WS0581 24 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 34557289 Common PNP polynucleotide phosphorylase/polyadenylase WS0899 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 161760549 Common nrdF ribonucleotide-diphosphate reductase subunit beta WS0420 157 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 34556818 Common - hypothetical protein WS0387 24 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 34558198 Common - hypothetical protein WS1904 31 None None None 34556639 Common tsf elongation factor Ts WS0193 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 34556984 Common - pyruvate carboxylase subunit B WS0565 208 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 34557710 Common - translation-associated GTPase WS1354 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 34556860 Common - hypothetical protein WS0433 10 COG3287 COG3287, Uncharacterized conserved protein Function unknown 34558379 Common DNAX DNA polymerase III subunits gamma and tau WS2096 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 34556822 Common - hypothetical protein WS0391 9 None None None 34558004 Common RPOA DNA-directed RNA polymerase subunit alpha WS1692 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 34556655 Common - HYBRID SENSORY HISTIDINE KINASE WS0212 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34557421 Common - hypothetical protein WS1036 16 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 34556867 Common ruvA Holliday junction DNA helicase motor protein WS0440 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 34557937 Common - hypothetical protein WS1620 2 None None None 34558352 Common - hypothetical protein WS2068 3 None None None 34556632 Common argS arginyl-tRNA synthetase WS0186 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557863 Common - hypothetical protein WS1534 42 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 34556648 Common WBGX WBGX PROTEIN WS0205 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 34557482 Common - hypothetical protein WS1104 3 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 34557453 Common oorC 2-oxoglutarate-acceptor oxidoreductase subunit OorC WS1070 65 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 34557489 Common - ABC TRANSPORTER, ATP-BINDING PROTEIN WS1112 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 34556879 Common TRXA THIOREDOXIN WS0452 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 34557298 Common ABCB ABCB PROTEIN WS0908 153 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 34557593 Common truD tRNA pseudouridine synthase D WS1227 87 COG0585 COG0585, Uncharacterized conserved protein Function unknown 34558203 Common WAAC LIPOPOLYSACCHARIDE HEPTOSYLTRANSFERASE-1 WS1909 58 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 34558024 Common rplB 50S ribosomal protein L2 WS1713 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 34556558 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase WS0106 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 34556788 Common DNAB replicative DNA helicase WS0354 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 34557902 Common - hypothetical protein WS1577 4 None None None 34558085 Common nusA transcription elongation factor NusA WS1778 219 COG0195 NusA, Transcription elongation factor Transcription 34556507 Common WLAB WLAB PROTEIN WS0052 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 34557178 Common FLDA flavodoxin FldA WS0778 72 COG0716 FldA, Flavodoxins Energy production and conversion 34556833 Common - PUTATIVE MFS TRANSPORTER WS0403 123 None None None 34556664 Common - DNA polymerase III subunit epsilon WS0221 186 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 34558036 Common - SIGNAL TRANSDUCTION RESPONSE REGULATOR WS1726 222 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 34558434 Common - hypothetical protein WS2155 41 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 34556529 Common RADA DNA repair protein RadA WS0075 201 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 34557949 Common gidA ADENYLATE CYCLASE WS1633 90 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 34558078 Common - hypothetical protein WS1771 3 None None None 34557603 Common - hypothetical protein WS1238 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 34558135 Common nuoB HYDROGENASE-Ni,Fe-hydrogenase III small subunit WS1836 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 34557035 Common CHEY RESPONSE REGULATOR WS0619 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557173 Common - hypothetical protein WS0773 16 None None None 34557579 Common cheR RESPONSE REGULATOR FOR CHEMOTAXIS, PROTEIN GLUTAMATEMETHYLTRANSFERASE WS1212 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 34557614 Common yajC preprotein translocase subunit YajC WS1249 165 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 34556829 Common YKOW YKOW PROTEIN WS0398 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34557263 Common TATC TRANSLOCASE PROTEIN TATC HOMOLOG WS0869 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 34557320 Common - hypothetical protein WS0931 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 34557023 Common PURC phosphoribosylaminoimidazole-succinocarboxamide synthase WS0607 198 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 34558310 Common - conserved hypothetical protein-ABC-type toluene export system, permease component WS2023 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 34557443 Common NTH ENDONUCLEASE III WS1060 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 34556806 Common - EXTRACELLULAR SOLUTE-BINDING PROTEIN, PUTATIVE WS0373 111 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 34558101 Common - TWO-COMPONENT RESPONSE REGULATOR WS1798 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557742 Common NIFK NITROGENASE BETA SUBUNIT WS1391 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 34558445 Common aroE shikimate 5-dehydrogenase WS2168 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 34558499 Common HTRA PROTEASE DO WS2226 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 34556627 Common - HYPOTHETICAL PROTEIN , PART OF CYTOCHROME OXIDASE? WS0180 7 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 34557089 Common truA tRNA pseudouridine synthase A WS0676 232 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 34558056 Common - putative sulfite oxidase subunit YedZ WS1749 71 COG2717 COG2717, Predicted membrane protein Function unknown 34558042 Common FOLP DIHYDROPTEROATE SYNTHASE WS1732 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 34558482 Common fliI flagellum-specific ATP synthase WS2207 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 34556871 Common rpmE 50S ribosomal protein L31 WS0444 179 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 34557628 Common YBTP YBTP PROTEIN WS1264 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 34557994 Common panD aspartate alpha-decarboxylase WS1682 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 34557992 Common - hypothetical protein WS1680 4 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 34557082 Common - hypothetical protein WS0669 10 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 34557329 Common - hypothetical protein WS0940 181 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 34556583 Common - hypothetical protein WS0134 6 None None None 34557186 Common - PHOSPHOMETHYLPYRIMIDINE KINASE WS0787 216 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 34557663 Common - PUTATIVE SODIUM/ALANINE SYMPORTER WS1301 117 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 34558076 Common - conserved hypothetical protein-2-methylthioadenine synthetase WS1769 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 34557755 Common - METHYLTRANSFERASE WS1405 86 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 34556962 Common - hypothetical protein WS0542 5 None None None 34556969 Common rimM PUTATIVE 16S RRNA PROCESSING PROTEIN WS0550 25 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 34556728 Common MOTB MOTB PROTEIN WS0292 146 COG1360 MotB, Flagellar motor protein Cell motility and secretion 34556596 Common - hypothetical protein WS0148 41 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 34557537 Nonpathogen - hypothetical protein WS1165 1 None None None 34557921 Common - O-sialoglycoprotein endopeptidase WS1600 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 34556586 Common - ATP-UTILIZING ENZYME OF THE PP-LOOP SUPERFAMILY WS0138 65 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 34556712 Common gltX glutamyl-tRNA synthetase WS0274 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 34556550 Common - hypothetical protein WS0098 3 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 34558123 Common - TRANSPORTER TRANSMEMBRANE PROTEIN-Putative threonine efflux protein WS1823 126 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 34557685 Common - HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN WS1325 98 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 34557780 Common - PUTATIVE TWO-COMPONENT REGULATOR WS1434 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34558458 Common CYSC adenylylsulfate kinase WS2182 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 34556490 Common FDXA hypothetical protein WS0032 77 COG1145 NapF, Ferredoxin Energy production and conversion 34557633 Common - PUTATIVE OUTER MEMBRANE COMPONENT OF EFFLUX SYSTEM WS1269 7 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 34557314 Common - hypothetical protein WS0925 10 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 34557176 Common - malate:quinone oxidoreductase WS0776 55 COG0579 COG0579, Predicted dehydrogenase General function prediction only 34556713 Common - hypothetical protein WS0276 86 None None None 34558196 Common dnaG DNA primase WS1902 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 34557892 Common - conserved hypothetical protein-High-affinity Fe2+/Pb2+ permease WS1566 83 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 34556556 Common - POSSIBLE PHOSPHATASE WS0104 148 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 34556674 Common FTSA CELL DIVISION PROTEIN FTSA WS0232 186 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 34556973 Common - arginine decarboxylase WS0554 146 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 34556935 Common ATPH F0F1 ATP synthase subunit delta WS0513 18 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 34556878 Common - hypothetical protein WS0451 86 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 34557740 Common NIFEN2 NIFEN2 WS1388 48 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 34556658 Nonpathogen - hypothetical protein WS0215 1 None None None 34558035 Common - hypothetical protein WS1725 20 COG1723 COG1723, Uncharacterized conserved protein Function unknown 34557938 Common - FIBRONECTIN/FIBRINOGEN-BINDING PROTEIN WS1621 47 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 34556671 Common - hypothetical protein WS0228 3 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 34556965 Common PERR PEROXIDE STRESS REGULATOR WS0545 194 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 34557615 Common NHAA NA(+)/H(+) ANTIPORTER 1 WS1251 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 34557786 Common - METHYLENETETRAHYDROFOLATE REDUCTASE WS1441 53 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 34558184 Common NIFR2 hypothetical protein WS1889 5 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 34557889 Common - ABC TRANSPORT PERMEASE PROTEIN-Involved in lipoprotein release WS1561 18 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 34556730 Common KDSA 2-dehydro-3-deoxyphosphooctonate aldolase WS0294 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 34557025 Common CLPB CLP PROTEASE ATP-BINDING SUBUNIT WS0609 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 34557982 Common - CELL DIVISION / PEPTIDOGLYCAN BIOSYNTHESIS PROTEIN WS1669 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 34558021 Common rpsC 30S ribosomal protein S3 WS1710 247 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 34557135 Common - PUTATIVE FERREDOXIN WS0730 78 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 34557606 Common - hypothetical protein WS1241 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 34558502 Common ruvC Holliday junction resolvase WS2229 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 34556585 Common - NCAIR MUTASE (PURE)-RELATED PROTEIN WS0137 66 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 34556718 Common - PUTATIVE METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS0281 57 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556819 Common - hypothetical protein WS0388 2 None None None 34558112 Common - MOLYBDENUM-PTERIN-BINDING PROTEIN WS1811 114 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 34557442 Common - hypothetical protein WS1059 2 None None None 34557425 Common - hypothetical protein WS1040 6 None None None 34558091 Common PPA inorganic pyrophosphatase WS1784 187 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 34557084 Common - nickel responsive regulator WS0671 53 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 34558028 Common - conserved hypothetical protein-Uncharacterized ATPase WS1717 14 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 34557596 Common TNPA PUTATIVE TRANSPOSASE WS1230 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34558175 Common minE cell division topological specificity factor MinE WS1880 48 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 34557182 Common - PUTATIVE PERIPLASMIC PROTEIN WS0783 9 COG3608 COG3608, Predicted deacylase General function prediction only 34556464 Common - hypothetical protein WS0005 7 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 34556931 Common - PARA FAMILY PROTEIN WS0509 232 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 34558493 Common - PUTATIVE ZINC PROTEASE WS2220 190 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 34556742 Common - TWO-COMPONENT REGULATOR WS0306 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34556651 Common - hypothetical protein WS0208 4 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 34556863 Common MURF D-ALANYL-D-ALANINE-ADDING ENZYME WS0436 191 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 34556986 Common - hypothetical protein WS0567 153 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 34558060 Common ARGF ORNITHINE CARBAMOYLTRANSFERASE WS1753 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 34558079 Common - hypothetical protein WS1772 4 None None None 34556565 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR WS0114 82 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 34556635 Common - hypothetical protein WS0189 4 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 34558138 Common nuoN HYDROGENASE 4 MEMBRANE SUBUNIT WS1839 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 34558223 Nonpathogen - hypothetical protein WS1929 2 None None None 34557526 Common - hypothetical protein WS1154 45 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 34556790 Common - hypothetical protein WS0356 18 COG2928 COG2928, Uncharacterized conserved protein Function unknown 34557904 Common - hypothetical protein WS1579 5 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 34556662 Common REP ribulose-phosphate 3-epimerase WS0219 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 34557324 Common - PUTATIVE TWO-COMPONENT SENSOR WS0935 150 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34556504 Nonpathogen - hypothetical protein WS0049 1 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 34558385 Nonpathogen - hypothetical protein WS2102 7 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 34557759 Common - hypothetical protein WS1409 45 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 34558080 Common - hypothetical protein WS1773 4 None None None 34557119 Common fdhA THIOSULFATE REDUCTASE .-.- WS0709 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34556956 Nonpathogen - hypothetical protein WS0536 3 None None None 34557433 Nonpathogen - hypothetical protein WS1049 1 None None None 34557696 Common - PUTATIVE SIGNAL-TRANSDUCTION SENSOR PROTEIN WS1338 93 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 34556866 Common - hypothetical protein WS0439 44 COG1944 COG1944, Uncharacterized conserved protein Function unknown 34557588 Common RIBA bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein WS1222 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 34558148 Common - PUTATIVE CYTOCHROME C-TYPE HAEM-BINDING PERIPLASMIC PROTEIN WS1850 23 None None None 34556870 Common cysS cysteinyl-tRNA synthetase WS0443 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34558454 Common - PUTATIVE SUGAR NUCLEOTIDYLTRANSFERASE WS2178 141 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 34557470 Common - CONJUGAL TRANSFER PROTEIN (TRAG) WS1091 60 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 34558117 Common - RESPONSE REGULATOR OMPR WS1817 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557735 Common fliM PUTATIVE NITROGEN FIXATION PROTEIN WS1383 26 None None None 34558298 Common - PUTATIVE PERIPLASMIC PROTEIN WS2011 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 34557449 Common SUCD SUCCINYL-COA SYNTHETASE ALPHA CHAIN WS1066 206 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 34556925 Common rplU 50S ribosomal protein L21 WS0503 168 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 34557581 Common - hypothetical protein WS1215 90 COG1739 COG1739, Uncharacterized conserved protein Function unknown 34557360 Common - hypothetical protein WS0972 174 COG1496 COG1496, Uncharacterized conserved protein Function unknown 34557738 Common flgK hypothetical protein WS1386 25 None None None 34556606 Common - SUHB-LIKE PROTEIN WS0158 22 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 34556681 Common SPOT GUANOSINE-PYROPHOSPHOHYDROLASE WS0240 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 34557399 Common - O-ACETYLHOMOSERINE SULFHYDRYLASE WS1012 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 34558154 Common - hypothetical protein WS1857 21 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 34556783 Common tyrA prephenate dehydrogenase WS0348 158 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 34556733 Common pyrF orotidine 5'-phosphate decarboxylase WS0297 163 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 34557682 Common - TRANSPORTER, NADC FAMILY WS1321 147 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 34557165 Common - MOLYBDOPTERIN OXIDOREDUCTASE, MOLYBDOPTERIN BINDING SUBUNIT WS0764 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34558314 Nonpathogen - hypothetical protein WS2028 1 None None None 34557676 Common - ABC TRANSPORTER INTEGRAL MEMBRANE PROTEIN WS1315 191 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 34557910 Common SODB SUPEROXIDE DISMUTASE WS1585 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 34556528 Common FTSY SIGNAL RECOGNITION PARTICLE PROTEIN WS0074 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 34556803 Common hemE uroporphyrinogen decarboxylase WS0370 176 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 34558007 Common rpsM 30S ribosomal protein S13 WS1695 246 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 34556724 Common - AraC-type DNA-binding proteins WS0288 126 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 34557546 Common napH quinol dehydrogenase membrane component WS1176 55 COG0348 NapH, Polyferredoxin Energy production and conversion 34556902 Common FDHB FORMATE DEHYDROGENASE, BETA SUBUNIT (FORMATEDEHYDROGENASE [NADP+]) WS0477 215 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 161760548 Common thrS threonyl-tRNA synthetase WS0820 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557033 Common hisH imidazole glycerol phosphate synthase subunit HisH WS0617 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 34557252 Common - hypothetical protein WS0858 9 None None None 34556667 Common PYRG CTP synthetase WS0224 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 34558106 Common MODB MOLYBDENUM TRANSPORT SYSTEM PERMEASE WS1804 227 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 34557390 Common CYSG SIROHEME SYNTHASE WS1003 202 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 34557012 Common ACS acetyl-CoA synthetase WS0595 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 34557121 Common - hypothetical protein WS0711 36 COG4747 COG4747, ACT domain-containing protein General function prediction only 34557998 Common - NI/FE HYDROGENASE WS1686 99 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 34557616 Common - HELICASE WS1252 176 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 34557515 Common - PUTATIVE FERREDOXIN WS1143 78 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 34557535 Common - hypothetical protein WS1163 26 COG4104 COG4104, Uncharacterized conserved protein Function unknown 34557254 Common - hypothetical protein WS0860 16 COG2962 RarD, Predicted permeases General function prediction only 34558363 Common - 50S ribosomal protein L25/general stress protein Ctc WS2079 156 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 34557678 Common - hypothetical protein WS1317 24 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 34558255 Common - hypothetical protein WS1967 15 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 34557061 Common - hypothetical protein WS0645 17 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 34557081 Common - hypothetical protein WS0668 54 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 34558235 Common CAC0985 ABC TRANSPORTER PERMEASE COMPONENT WS1944 166 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 34558077 Common - conserved hypothetical protein-Predicted ATPase of the PP-loop superfamily implicated in cell cycle control WS1770 145 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 34558168 Common rpsF 30S ribosomal protein S6 WS1873 207 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 34556645 Common flhB hypothetical protein WS0201 5 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 34556682 Common TYRS tyrosyl-tRNA synthetase WS0241 241 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557274 Common smpB SsrA-binding protein WS0883 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 34556762 Common TRXB_2 PUTATIVE THIOREDOXIN REDUCTASE WS0327 102 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 34557647 Nonpathogen - hypothetical protein WS1283 1 None None None 161760544 Common uvrA excinuclease ABC subunit A WS1628 241 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 34557475 Common COMB1 COMB1 WS1096 15 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 34558212 Common - hypothetical protein WS1918 3 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34556910 Common NUOL NADH dehydrogenase subunit L WS0485 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 34557777 Common fdhB PUTATIVE OXIDOREDUCTASE, FE-S SUBUNIT WS1431 161 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34556616 Common ACRD CATION EFFLUX (ACRB/ACRD/ACRF FAMILY) WS0168 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 34556502 Common - PUTATIVE GLYCOSYLTRANSFERASE PROTEIN WS0047 158 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 34558349 Common - acetyltransferase WS2064 86 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 34558401 Common glyQ glycyl-tRNA synthetase subunit alpha WS2118 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 34558442 Common PURM phosphoribosylaminoimidazole synthetase WS2165 228 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 34557227 Common FRDA fumarate reductase WS0831 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 34557264 Common - sec-independent translocase WS0870 8 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 34557849 Common - INTEGRAL MEMBRANE PROTEIN-Small-conductance mechanosensitive channel WS1516 17 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 34557063 Nonpathogen - hypothetical protein WS0647 1 None None None 34557149 Common - IMMUNOGENIC PROTEIN WS0748 83 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 34556814 Common - PUTATIVE NITRATE REDUCTASE, FORMATE DEPENDENT WS0382 41 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 34557799 Common - hypothetical protein WS1455 4 None None None 34556753 Common - PUTATIVE MFS METABOLITE TRANSPORTER WS0317 71 None None None 34557862 Common rpoB TRANSCRIPTIONAL REGULATOR WS1533 135 COG1802 GntR, Transcriptional regulators Transcription 34558055 Common - putative sulfite oxidase subunit YedY WS1748 125 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 34557704 Common lacA ribose-5-phosphate isomerase B WS1348 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 34558360 Common - hypothetical protein WS2076 11 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 34556943 Common tolB translocation protein TolB WS0521 124 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 34557499 Common - ABC-TYPE IRON (III) TRANSPORT SYSTEM WS1124 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 34557381 Common - TONB-DEPENDENT RECEPTOR WS0993 77 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 34558330 Common - PUTATIVE PERIPLASMIC PROTEIN-TRXB WS2045 8 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 34557661 Common - hypothetical protein WS1299 143 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 34556573 Common FCCA FLAVOCYTOCHROME C FLAVIN SUBUNIT WS0124 211 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 34558262 Common - flagellar assembly protein FliW WS1974 12 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 34557249 Common - PUTATIVE DIAMINOBUTYRIC ACID ACETYLTRANSFERASE WS0854 29 COG0456 RimI, Acetyltransferases General function prediction only 34558398 Common - PUTATIVE RIBOSOMAL PSEUDOURIDINE SYNTHASE WS2115 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 34557968 Common valS valyl-tRNA synthetase WS1652 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557397 Common CYSH APS REDUCTASE WS1010 160 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 34557779 Common - hypothetical protein WS1433 8 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 34556751 Common pyrE orotate phosphoribosyltransferase WS0315 113 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 34556974 Common - hypothetical protein WS0555 208 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 34558414 Common - pyruvate flavodoxin oxidoreductase subunit gamma WS2132 56 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 34557458 Common - PUTATIVE AMINOTRANSFERASE (DEGT FAMILY) WS1076 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 34556661 Common FBP fructose-1,6-bisphosphatase WS0218 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 34556610 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR WS0162 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 34557170 Common - MULTIDRUG RESISTANCE PROTEIN MEXB WS0770 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 34557238 Common plsC hypothetical protein WS0842 7 None None None 34556909 Common NUOK NADH dehydrogenase subunit K WS0484 165 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 34558491 Common - hypothetical protein WS2218 5 None None None 34557659 Common - hypothetical protein WS1296 13 COG4802 FtrB, Ferredoxin-thioredoxin reductase, catalytic subunit Energy production and conversion 34557793 Common hisS histidyl-tRNA synthetase WS1449 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557091 Common - hypothetical protein WS0678 131 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 34558083 Common - conserved hypothetical protein-2-methylthioadenine synthetase WS1776 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 34558240 Common - polyphosphate kinase WS1949 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 34558354 Common hisB IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE WS2070 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 34557204 Common - hypothetical protein WS0806 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34557288 Common - hypothetical protein WS0898 70 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 34557649 Common - hypothetical protein WS1285 8 COG1847 Jag, Predicted RNA-binding protein General function prediction only 34557507 Common ciaB CiaB PROTEIN WS1133 5 None None None 34558274 Common - hypothetical protein WS1986 21 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 34557317 Common - hypothetical protein WS0928 8 None None None 34557587 Common - INTEGRASE-RECOMBINASE PROTEIN XERCD FAMILY WS1221 222 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 34557595 Common - PUTATIVE MCP-TYPE SIGNAL TRANSDUCTION PROTEIN WS1229 111 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34558451 Common - PUTATIVE NUCLEOTIDE PHOSPHORIBOSYLTRANSFERASE WS2175 79 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 34557825 Common MUTS recombination and DNA strand exchange inhibitor protein WS1486 120 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 34558463 Common WBPD PUTATIVE ACETYLTRANSFERASE WS2187 215 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 34557689 Common - PUTATIVE PERIPLASMIC PROTEIN WS1329 4 None None None 34557276 Common EXBD hypothetical protein WS0886 54 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 34558473 Common FLAB flagellin WS2198 115 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 34557834 Common aroK shikimate kinase WS1497 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 34556831 Common DCTA PUTATIVE C4-DICARBOXYLATE TRANSPORT PROTEIN WS0400 157 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 34557698 Common - PUTATIVE TWO-COMPONENT SENSOR WS1340 200 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34558339 Common PDP PDP PROTEIN WS2054 7 COG3334 COG3334, Uncharacterized conserved protein Function unknown 34557400 Common - hypothetical protein WS1013 46 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 34556489 Common - hypothetical protein WS0031 37 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 34556545 Common ILVE branched-chain amino acid aminotransferase WS0092 216 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 34556580 Common - hypothetical protein WS0131 127 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 34557122 Common MTH1855 COENZYME F390 SYNTHETASE II WS0712 130 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 34558173 Common ilvC ketol-acid reductoisomerase WS1878 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 34557110 Common recR recombination protein RecR WS0699 203 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 34557188 Common HYPF TRANSCRIPTIONAL REGULATORY PROTEIN HYPF WS0790 111 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 34556894 Common rps7 30S ribosomal protein S7 WS0469 247 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 34557058 Common DGKA DIACYLGLYCEROL KINASE WS0642 82 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 34557746 Nonpathogen - hypothetical protein WS1395 1 None None None 34557569 Common moaC molybdenum cofactor biosynthesis protein C WS1200 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 34558244 Common - SIGNAL TRANSDUCTION REGULATORY PROTEIN-CheY like receiver domain WS1954 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557719 Common - PUTATIVE ATP /GTP BINDING PROTEIN WS1366 36 COG3596 COG3596, Predicted GTPase General function prediction only 34556744 Common groEL chaperonin GroEL WS0308 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 34557572 Nonpathogen ftsA hypothetical protein WS1204 1 None None None 34556797 Nonpathogen - hypothetical protein WS0364 1 None None None 34557842 Common - NAD(P)H-FLAVIN OXIDOREDUCTASE WS1508 120 COG0778 NfnB, Nitroreductase Energy production and conversion 34556530 Common - hypothetical protein WS0076 2 None None None 34557410 Common - hypothetical protein WS1024 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34556478 Common - hypothetical protein WS0020 16 COG4887 COG4887, Uncharacterized metal-binding protein conserved in archaea General function prediction only 34557621 Common lolA outer-membrane lipoprotein carrier protein WS1257 11 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 34557811 Common LIVM ABC TRANSPORT SYSTEM PERMEASE PROTEIN WS1468 146 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 34558464 Common WBPB PUTATIVE OXIDOREDUCTASE WS2188 68 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 34557322 Common - ACETOLACTATE SYNTHASE WS0933 36 COG4747 COG4747, ACT domain-containing protein General function prediction only 34557872 Common - DEOXYRIBODIPYRIMIDINE PHOTOLYASE DNA PHOTOLYASEPHOTOREACTIVATING ENZYME WS1544 132 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 34557915 Common - hypothetical protein WS1591 4 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 34556537 Common lysS lysyl-tRNA synthetase WS0084 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 34557281 Nonpathogen - hypothetical protein WS0891 1 None None None 34557417 Common - MAGNESIUM AND COBALT TRANSPORT PROTEIN WS1032 164 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 34556618 Common mraW S-adenosyl-methyltransferase MraW WS0170 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 34558319 Common - hypothetical protein WS2033 3 None None None 34557560 Nonpathogen - hypothetical protein WS1191 7 None None None 34557356 Common NRFI NRFI PROTEIN WS0968 81 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 34557349 Nonpathogen - hypothetical protein WS0961 1 None None None 34557334 Common pstB PHOSPHATE ABC TRANSPORTER WS0945 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 34558127 Common TRPA TRYPTOPHAN SYNTHASE ALPHA CHAIN WS1827 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 34558286 Common fliF flagellar MS-ring protein WS1999 127 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 34557804 Common - PUTATIVE TAUTOMERASE WS1461 42 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 34556848 Common - hypothetical protein WS0419 101 COG0388 COG0388, Predicted amidohydrolase General function prediction only 34558159 Common DCTQ SMALL INTEGRAL C4-DICARBOXYLATE MEMBRANE TRANSPORT PROTEIN,PUTATIVE WS1864 52 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 34558377 Common TRMA tRNA (uracil-5-)-methyltransferase WS2094 188 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 34557046 Common ACPP ACYL CARRIER PROTEIN (ACP) WS0630 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 34557102 Common LIN LIN1550 PROTEIN WS0691 170 COG1959 COG1959, Predicted transcriptional regulator Transcription 34558430 Common - PUTATIVE PERIPLASMIC PROTEIN WS2151 33 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 34558067 Common flgD flagellar basal body rod modification protein WS1760 24 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 34557195 Nonpathogen - hypothetical protein WS0797 1 None None None 34557407 Common DGC3 DIGUANYLATE CYCLASE (FRAGMENT) WS1021 225 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 34557340 Common - SENSORY TRASNDUCTION HISTIDINE KINASE WS0951 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 34558375 Common MOTB HYPOTHETICAL PROTEIN-PUTATIVE FLAGELLAR MOTOR PROTEIN WS2092 128 COG1360 MotB, Flagellar motor protein Cell motility and secretion 34556880 Common - hypothetical protein WS0453 3 None None None 34557244 Common - hypothetical protein WS0848 171 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 34556494 Common wlaK AMINOTRANSFERASE HOMOLOG WS0037 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 34556887 Common nusG transcription antitermination protein NusG WS0462 215 COG0250 NusG, Transcription antiterminator Transcription 34557712 Nonpathogen - hypothetical protein WS1356 1 None None None 34557906 Common hemA glutamyl-tRNA reductase WS1581 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 34558161 Common - hypothetical protein WS1866 88 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 34557211 Common CDSA PHOSPHATIDATE CYTIDYLYLTRANSFERASE WS0813 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 34557181 Nonpathogen clpA hypothetical protein WS0782 1 None None None 34558141 Common nuoL HYDROGENASE 4 MEMBRANE SUBUNIT WS1842 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 34556923 Nonpathogen FTSI hypothetical protein WS0500 1 None None None 34557958 Common flhF flagellar biosynthesis regulator FlhF WS1642 245 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 34558370 Common argC N-acetyl-gamma-glutamyl-phosphate reductase WS2086 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 34556563 Common panC pantoate--beta-alanine ligase WS0112 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 34556678 Common - acyl-CoA synthetase WS0237 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 34558022 Common rplV 50S ribosomal protein L22 WS1711 222 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 34558429 Common dapF diaminopimelate epimerase WS2150 186 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 34557680 Common - hypothetical protein WS1319 13 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 34556756 Common thiB hypothetical protein WS0320 23 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 34557351 Common BDHA BUTANOL DEHYDROGENASE WS0963 169 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 34557591 Common folE GTP cyclohydrolase I WS1225 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 34557782 Common - PUTATIVE TWO-COMPONENT SENSOR WS1436 184 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34556691 Nonpathogen - hypothetical protein WS0251 2 None None None 34557006 Common - hypothetical protein WS0589 56 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 34556516 Common - hypothetical protein WS0062 195 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 34557894 Common MLL1446 MLL1446 PROTEIN WS1568 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34557947 Common - hypothetical protein WS1631 16 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 34556706 Common GLCD GLYCOLATE OXIDASE SUBUNIT GLCD WS0267 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 34556518 Common HISF CYCLASE HISF WS0064 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 34558342 Common hisZ ATP phosphoribosyltransferase regulatory subunit WS2057 42 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34556461 Common gyrB DNA gyrase subunit B WS0002 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 34558439 Common - hypothetical protein WS2160 33 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 34557971 Common LEPA GTP-binding protein LepA WS1655 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 34558208 Common - conserved hypothetical protein-Predicted Fe-S-cluster oxidoreductase WS1914 19 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 34557687 Common - hypothetical protein WS1327 6 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 34556480 Common GLMS D-fructose-6-phosphate amidotransferase WS0022 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 34557871 Common - conserved hypothetical protein-Acetyltransferase, including N-acetylase of ribosomal proteins WS1543 66 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 34556637 Common fliR flagellar biosynthesis protein FliR WS0191 113 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 34557326 Common nuoM hypothetical protein WS0937 43 COG5557 COG5557, Polysulphide reductase Energy production and conversion 34557827 Common fliQ flagellar biosynthesis protein FliQ WS1489 118 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 34558044 Common - hypothetical protein WS1734 5 None None None 34557715 Nonpathogen - hypothetical protein WS1362 1 None None None 34558089 Common adk adenylate kinase WS1782 230 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 34558189 Common METY O-ACETYLHOMOSERINE (THIOL)-LYASE WS1894 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 34558500 Common - hypothetical protein WS2227 5 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 34558389 Common - PUTATIVE POLYSACCHARIDE BIOSYNTHESIS PROTEIN WS2106 83 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 34557065 Common - COBALT TRANSPORT ATP-BINDING PROTEIN O WS0649 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 34557096 Common - anaerobic ribonucleoside triphosphate reductase WS0684 105 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 34557919 Common - hypothetical protein WS1598 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 34557990 Common surE stationary phase survival protein SurE WS1678 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 34556594 Common - CELL DIVISION PROTEIN FTSE WS0146 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 34558032 Common - coproporphyrinogen III oxidase WS1722 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 34558425 Common - hypothetical protein WS2146 7 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 34557293 Common MEXD MULTIDRUG EFFLUX TRANSPORTER WS0903 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 34557078 Nonpathogen - hypothetical protein WS0663 1 None None None 34557951 Common PRSA ribose-phosphate pyrophosphokinase WS1635 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 34558384 Nonpathogen - hypothetical protein WS2101 1 None None None 34557184 Common - hypothetical protein WS0785 133 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 34557574 Common - PUTATIVE HISTIDINE KINASE (FRAGMENT) WS1207 121 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34557307 Common - hypothetical protein WS0918 13 None None None 34556673 Common FTSZ cell division protein FtsZ WS0231 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 34557684 Common PT PHOSPHOTYROSINE PROTEIN PHOSPHATASE WS1323 140 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 34558194 Common rnhA ribonuclease H WS1900 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 34557874 Common - ARSENICAL PUMP-DRIVING ATPASE WS1546 87 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 34556711 Common - hypothetical protein WS0273 68 COG0762 COG0762, Predicted integral membrane protein Function unknown 34556876 Common - aspartate aminotransferase WS0449 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 34557174 Common - hypothetical protein WS0774 78 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 34558182 Common - hypothetical protein WS1887 7 None None None 34558052 Nonpathogen - hypothetical protein WS1743 4 None None None 34557447 Common CITH MALATE DEHYDROGENASE WS1064 174 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 34557266 Common SERS seryl-tRNA synthetase WS0872 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 34558009 Common MAP methionine aminopeptidase WS1697 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 34556554 Common ilvH acetolactate synthase 3 regulatory subunit WS0102 190 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 34557984 Common - hypothetical protein WS1671 12 None None None 34558440 Common - PUTATIVE METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS2163 88 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556799 Common - hypothetical protein WS0366 2 None None None 34556687 Nonpathogen trmU hypothetical protein WS0247 2 None None None 34556716 Common - BINDING COMPONENT OF ABC TRANSPORTER WS0279 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 34557962 Common purT phosphoribosylglycinamide formyltransferase 2 WS1646 194 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 34556927 Common obgE GTPase ObgE WS0505 249 COG0536 Obg, Predicted GTPase General function prediction only 34556937 Common ATPG F0F1 ATP synthase subunit gamma WS0515 207 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 34557086 Common - hypothetical protein WS0673 17 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 34558131 Nonpathogen - hypothetical protein WS1832 2 None None None 34556591 Common - PUTATIVE RIBOSOMAL PSEUDOURIDINE SYNTHASE WS0143 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 34558000 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase WS1688 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 34558026 Common rplD 50S ribosomal protein L4 WS1715 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 34556828 Common - PUTATIVE THIF PROTEIN WS0397 220 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 34557533 Nonpathogen - hypothetical protein WS1161 1 COG4872 COG4872, Predicted membrane protein Function unknown 34558110 Common MODA MOLYBDATE PERIPLASMIC BINDING PROTEIN WS1809 93 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 34556933 Common ATPF' F0F1 ATP synthase subunit B' WS0511 13 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 34558058 Common HEMN coproporphyrinogen III oxidase WS1751 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 34556509 Common RHPR PUTATIVE TWO-COMPONENT REGULATOR WS0055 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34556612 Common - hypothetical protein WS0164 53 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 34558495 Common - 7-alpha-hydroxysteroid dehydrogenase WS2222 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 34557869 Common - ACYL-COA HYDROLASE WS1541 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 34556500 Common WLAE WLAE PROTEIN WS0044 170 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 34557912 Common - hypothetical protein WS1588 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 34557440 Common - hypothetical protein WS1057 4 None None None 34557887 Common - ABC TRANSPORT PROTEIN WS1559 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 34557797 Common gltA type II citrate synthase WS1453 191 COG0372 GltA, Citrate synthase Energy production and conversion 34557809 Common LIVF ABC TRANSPORT SYSTEM ATP-BINDING PROTEIN WS1466 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 34556755 Nonpathogen - hypothetical protein WS0319 1 None None None 34557860 Common accA L(+)-tartrate dehydratase subunit beta WS1529 146 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 34556881 Common TRXB THIOREDOXIN REDUCTASE WS0454 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 34558013 Common rplR 50S ribosomal protein L18 WS1701 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 34556912 Common - NADH dehydrogenase subunit N WS0488 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 34557655 Common era GTP-binding protein Era WS1292 218 COG1159 Era, GTPase General function prediction only 34557138 Common FDHA FORMATE DEHYDROGENASE PRECURSOR WS0733 193 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34557347 Common TNPA PUTATIVE TRANSPOSASE WS0959 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557802 Common - hypothetical protein WS1458 70 COG1432 COG1432, Uncharacterized conserved protein Function unknown 34558266 Common - hypothetical protein WS1978 17 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 34557640 Common - arginyl-tRNA-protein transferase WS1276 86 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 34558408 Common - PUTATIVE SHORT-CHAIN DEHYDROGENASE WS2125 235 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 34557926 Common - hypothetical protein WS1606 7 None None None 34558166 Common rpsR 30S ribosomal protein S18 WS1871 211 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 34558301 Common - hypothetical protein WS2014 7 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 34556785 Common - hypothetical protein WS0351 82 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 34557209 Common - hypothetical protein WS0811 19 None None None 34557731 Common KTRB PUTATIVE K+ UPTAKE PROTEIN WS1379 87 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 34557961 Common AROQ 3-dehydroquinate dehydratase WS1645 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 34556727 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN DEDA HOMOLOG WS0291 143 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 34558341 Common PURA adenylosuccinate synthetase WS2056 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 161760546 Common - recombination factor protein RarA WS1256 248 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 34557765 Common - PROBABLE OUTER MEMBRANE PROTEIN WS1417 127 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 34558308 Common - conserved hypothetical protein-Permease component of an ABC-transporter WS2021 66 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 34556492 Nonpathogen - hypothetical protein WS0035 1 None None None 34558217 Common - PUTATIVE METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS1923 134 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34558312 Common ileS hypothetical protein WS2026 51 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 34557484 Nonpathogen - hypothetical protein WS1106 1 None None None 34557583 Common - PUTATIVE MCP-TYPE SIGNAL TRANSDUCTION PROTEIN WS1217 125 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557543 Common - PUTATIVE PERIPLASMIC PROTEIN WS1171 12 COG2319 COG2319, FOG: WD40 repeat General function prediction only 34556484 Common FDHD formate dehydrogenase accessory protein WS0026 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 34556587 Common - hypothetical protein WS0139 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 34557339 Common - SENSORY TRANSDUCTION REGULATOR WS0950 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34558485 Common - hypothetical protein WS2211 22 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34556851 Common tagE hypothetical protein WS0422 22 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 34557465 Common - hypothetical protein WS1084 2 None None None 34557555 Common - INTEGRAL MEMBRANE PROTEIN WS1186 40 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 34556900 Common NUOD NADH dehydrogenase subunit D WS0475 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 34557941 Common - hypothetical protein WS1624 2 None None None 34557377 Common - DNA-DAMAGE-INDUCIBLE PROTEIN WS0989 172 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 34557411 Common - hypothetical protein WS1025 11 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 34557486 Common - PROBABLE TRANSCRIPTIONAL REGULATOR WS1109 30 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 34557790 Common - hypothetical protein WS1445 25 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 34557250 Common - diaminobutyrate--2-oxoglutarate aminotransferase WS0855 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 34557544 Common NAPF HYPOTHETICAL PROTEIN , NapF domain WS1172 51 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 34558270 Common - hypothetical protein WS1982 58 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 34556526 Common - hypothetical protein WS0072 11 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 34558233 Common MRP PUTATIVE ATP/GTP-BINDING PROTEIN (MRP HOMOLOG) WS1942 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 34556976 Common UNG uracil-DNA glycosylase WS0557 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 34557492 Common UAHA UREA AMIDOLYASE-RELATED PROTEIN WS1115 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 34558116 Common - hypothetical protein WS1815 3 None None None 34557370 Common NIKA PUTATIVE NIKA PROTEIN WS0982 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 34557997 Common HYAC NI/FE-HYDROGENASE CYTOCHROME B WS1685 49 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 34558071 Common NRDA ribonucleotide-diphosphate reductase subunit alpha WS1764 219 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 34557259 Common - hypothetical protein WS0865 6 None None None 34557388 Common - hypothetical protein WS1001 27 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 34557513 Common - hypothetical protein WS1140 5 None None None 34557014 Common - hypothetical protein WS0597 66 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 34558365 Common SERB PUTATIVE PHOSPHOSERINE PHOSPHATASE WS2081 154 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 34557409 Nonpathogen - hypothetical protein WS1023 1 None None None 34556496 Common WCGN PUTATIVE PHOSPHATE TRANSFERASE WS0039 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 34557231 Common MOEA MOEA PROTEIN WS0835 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 34558288 Common - PHOSPHOMANNOMUTASE WS2001 235 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 34557832 Common - hypothetical protein WS1495 7 None None None 34558475 Common - PUTATIVE TWO-COMPONENT SENSOR WS2200 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34558242 Common - TRANSMEMBRANE TRANSPORT PROTEIN-PERMEASE WS1952 60 None None None 34558337 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein WS2052 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 34556992 Common - hypothetical protein WS0573 20 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 34557291 Common - GGDEF FAMILY PROTEIN WS0901 91 COG3287 COG3287, Uncharacterized conserved protein Function unknown 34557202 Common hisG ATP phosphoribosyltransferase catalytic subunit WS0804 211 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 34557792 Nonpathogen - hypothetical protein WS1447 1 None None None 34556746 Common ASPB aspartate aminotransferase WS0310 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 34556989 Common - ATP-BINDING COMPONENT OF ABC TRANSPORTER WS0570 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 34557494 Common gatA amidase WS1118 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 34557624 Common - hypothetical protein WS1260 5 COG2921 COG2921, Uncharacterized conserved protein Function unknown 34557049 Nonpathogen ksgA hypothetical protein WS0633 4 None None None 34558249 Nonpathogen - hypothetical protein WS1959 1 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34557844 Common - MCP-SIGNAL TRANSDUCTION PROTEIN WS1510 60 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34558228 Common PGPA PHOSPHATIDYLGLYCEROPHOSPHATASE A WS1937 56 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 34557657 Common hslV ATP-dependent protease peptidase subunit WS1294 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 34557163 Common pstS PUTATIVE PHOSPHATE ABC TRANSPORTER WS0762 121 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 34557529 Common - ATP-BINDING PROTEIN WS1157 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 34556780 Common GAPA GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE WS0345 218 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 34556941 Common EXBD3 EXBD\TOLR FAMILY TRANSPORT PROTEIN WS0519 126 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 34556907 Common NUOI NADH dehydrogenase subunit I WS0482 185 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 34557854 Common - hypothetical protein WS1521 9 None None None 34557813 Common LIVK ABC TRANSPORT SYSTEM PERIPLASMIC BINDING PROTEIN WS1471 144 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 34557562 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR WS1193 144 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 34557638 Common NADA quinolinate synthetase WS1274 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 34558329 Common - hypothetical protein WS2044 17 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 34557042 Common STRA SULFUR TRANSFERASE PRECURSOR WS0626 28 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 34557520 Common FDHC FORMATE DEHYDROGENASE SUBUNIT C PRECURSOR WS1148 68 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 34557225 Common FRDC2 FRDC2 PROTEIN WS0829 10 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 34557027 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase WS0611 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 34556977 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C WS0558 67 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 34556575 Common FLPF PUTATIVE FORMATE DEHYDROGENASE, ALPHA SUBUNIT WS0126 189 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 34557319 Common - hypothetical protein WS0930 23 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 34556793 Common - hypothetical protein WS0360 4 None None None 34557631 Common - PUTATIVE MFS TRANSPORTER WS1267 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 34557922 Common - PUTATIVE THIOL PEROXIDASE-SCAVENGASE P20 OXIDOREDU WS1601 98 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 34556980 Common - transketolase WS0561 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 34557436 Common - hypothetical protein WS1052 9 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 34558120 Nonpathogen - hypothetical protein WS1820 1 None None None 34557618 Common - PUTATIVE TRANSCRIPTIONAL REGULATOR WS1254 87 COG0789 SoxR, Predicted transcriptional regulators Transcription 34558391 Common - FLAGELLAR PROTEIN G FLAG WS2108 67 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 34558268 Common - ABC TRANSPORTER, ATP-BINDING PROTEIN WS1980 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 34557891 Common - PERIPLASMIC PROTEIN-probably involved in high-affinity Fe2+ transport WS1564 25 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 34557031 Common - hypothetical protein WS0615 30 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 34557908 Common - hypothetical protein WS1583 4 None None None 34558019 Common rpsQ 30S ribosomal protein S17 WS1707 216 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 34558069 Nonpathogen - hypothetical protein WS1762 1 None None None 34557153 Common ARSB ARSENIC EFFLUX PUMP PROTEIN WS0752 130 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 34558437 Common - hypothetical protein WS2158 15 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 34558272 Nonpathogen - hypothetical protein WS1984 1 None None None 34557709 Common PEPA leucyl aminopeptidase WS1353 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 34557978 Common - PENICILLIN-BINDING PROTEIN / CELL DIVISION PROTEIN WS1663 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 34557002 Common HLYA PUTATIVE HEMOLYSIN WS0585 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 34557224 Common grpE hypothetical protein WS0828 2 None None None 34557104 Common - TWO-COMPONENT RESPONSE REGULATOR WS0693 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 34556949 Common PFS 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase WS0528 101 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 34557193 Common HYPE HYDROGENASE EXPRESSION/FORMATION PROTEIN WS0795 143 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 34557044 Common ACCA acetyl-CoA carboxylase carboxyltransferase subunit alpha WS0628 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 34557551 Common - hypothetical protein WS1181 51 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 34558143 Common - ALDEHYDE FERREDOXIN OXIDOREDUCTASE WS1844 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 34557004 Common - hypothetical protein WS0587 66 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 34557901 Common - hypothetical protein WS1576 7 None None None 34558373 Common - UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE GLMU WS2089 226 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 34557143 Common - ORF7 PROTEIN WS0739 38 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 34557137 Nonpathogen - hypothetical protein WS0732 1 None None None 34557668 Common pheS phenylalanyl-tRNA synthetase subunit alpha WS1307 248 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 34556708 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase WS0269 140 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 34557721 Nonpathogen - hypothetical protein WS1368 1 None None None 34558206 Common TRPC INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE WS1912 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 34556758 Common murG N-acetylglucosaminyl transferase WS0323 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 34558320 Nonpathogen - hypothetical protein WS2034 1 None None None 34556950 Common - MLL7959 PROTEIN WS0529 68 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 34556676 Common BIOA adenosylmethionine--8-amino-7-oxononanoate transaminase WS0234 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 34557761 Common feoB PUTATIVE FERROUS IRON TRANSPORT PROTEIN B WS1412 206 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 34557896 Common MTAA METAL TRANSPORTING ATPASE MTA72 WS1571 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 34558264 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase WS1976 212 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 34557713 Common serA CYTOSINE DEAMINASE WS1357 205 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 34558466 Common - hypothetical protein WS2190 13 None None None 34557112 Common alr alanine racemase WS0701 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 34558152 Nonpathogen - hypothetical protein WS1854 1 None None None 34557366 Common OPP-1D PUTATIVE OLIGOPEPTIDE TRANSPORTER WS0978 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 34557387 Common - hypothetical protein WS1000 4 None None None 34556892 Common RPOB DNA-directed RNA polymerase subunit beta/beta' WS0467 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 34557456 Common - biotin carboxylase WS1074 238 COG0439 AccC, Biotin carboxylase Lipid metabolism 34557283 Nonpathogen - hypothetical protein WS0893 1 None None None 34557917 Nonpathogen - hypothetical protein WS1593 2 None None None 34557744 Nonpathogen - hypothetical protein WS1393 1 None None None 34557124 Common - INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA .-.-IORINDOLEPYRUVATE FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT WS0714 106 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 34556543 Common - PUTATIVE PHOSPHOHYDROLASE WS0090 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 34556693 Common - hypothetical protein WS0253 4 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 34557623 Common - hypothetical protein WS1259 146 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 34558253 Common - hypothetical protein WS1965 4 None None None 34556605 Common ACCD acetyl-CoA carboxylase subunit beta WS0157 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 34557233 Common - hypothetical protein WS0837 96 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 34557953 Common fliY flagellar motor switch protein FliY WS1637 119 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 34556624 Common ileS isoleucyl-tRNA synthetase WS0176 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34558303 Common infB translation initiation factor IF-2 WS2016 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 34557881 Common - ALKYLPHOSPHONATE ABC TRANPORTER (PERMEASE) WS1553 102 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 34556511 Common MREB PUTATIVE ROD SHAPE-DETERMINING PROTEIN WS0057 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 34558317 Nonpathogen - hypothetical protein WS2031 1 None None None 34557160 Nonpathogen - hypothetical protein WS0759 3 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 34558125 Common ruvB Holliday junction DNA helicase B WS1825 220 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 34558221 Common - HYPOTHETICAL PROTEIN-Signal transduction histidine kinase WS1927 196 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34556770 Common bioD Putative Dethiobiotin synthetase WS0335 154 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 34558014 Common rplF 50S ribosomal protein L6 WS1702 233 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 34557332 Common - hypothetical protein WS0943 98 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34558157 Common RHPS SENSOR KINASE OF TWO-COMPONENT REGULATORY SYSTEM WS1861 215 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34558097 Common - MULTIDRUG-EFFLUX TRANSPORTER WS1793 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 34557093 Common WAAE PUTATIVE ADP-HEPTOSE SYNTHASE WS0680 154 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 34557505 Common - hypothetical protein WS1130 8 None None None 34557402 Common - O-ACETYLHOMOSERINE SULFHYDRYLASE WS1015 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 34557734 Common - hypothetical protein WS1382 23 COG0633 Fdx, Ferredoxin Energy production and conversion 34557463 Common TNPA PUTATIVE TRANSPOSASE WS1081 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34558291 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase WS2004 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 34557541 Common - MULTIMERIC FLAVODOXIN WRBA FAMILY PROTEIN WS1169 52 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 34558158 Common DCTP C4-DICARBOXYLATE-BINDING PERIPLASMIC PROTEIN PRECURSOR WS1863 114 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 34558304 Common rbfA ribosome-binding factor A WS2017 12 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 34557815 Common purU formyltetrahydrofolate deformylase WS1475 216 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 34557473 Common COMB3 COMB3 WS1094 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 34557460 Common CHEW PUTATIVE CHEMOTAXIS PROTEIN CHEW WS1078 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 34557556 Common ACNB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase WS1187 221 COG1049 AcnB, Aconitase B Energy production and conversion 34557672 Common rpsA 30S ribosomal protein S1 WS1311 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 34557890 Common - INTEGRAL MEMBRANE PROTEIN WS1562 18 COG4393 COG4393, Predicted membrane protein Function unknown 34557964 Common - hypothetical protein WS1648 110 COG2606 EbsC, Uncharacterized conserved protein Function unknown 34558239 Common - ACETYLTRANSFERASE WS1948 207 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 34558311 Common - PUTATIVE SIGNAL-TRANSDUCTION SENSOR PROTEIN WS2025 91 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 34558369 Common - hypothetical protein WS2085 22 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 34558287 Common HISC histidinol-phosphate aminotransferase WS2000 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 34558367 Common CHEA HISTIDINE KINASE WS2083 222 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 34557372 Common NIKA PUTATIVE NIKA PROTEIN WS0984 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 34556921 Common flgL flagellar hook-associated protein FlgL WS0498 46 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 34556482 Common - ASPARTATE AMINOTRANSFERASE WS0024 160 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 34558417 Common rpsI 30S ribosomal protein S9 WS2137 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 34557469 Common - hypothetical protein WS1089 4 None None None 34556787 Common RECG ATP-DEPENDENT DNA HELICASE WS0353 211 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 34557548 Common NAPA PERIPLASMIC NITRATE REDUCTASE WS1178 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 34557519 Common FDHB PUTATIVE FORMATE DEHYDROGENASE IRON-SULFUR SUBUNIT WS1147 181 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34558232 Common thiC thiamine biosynthesis protein ThiC WS1941 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 34558399 Common - 3-deoxy-D-manno-octulosonic-acid transferase WS2116 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 34558038 Common YFFD NUCLEOSIDE POLYPHOSPHATE HYDROLASE WS1728 36 None None None 34558114 Common - ISOPROPYLMALATE DEHYDROGENASE WS1813 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 34556525 Common - hypothetical protein WS0071 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 34558350 Common - GTPase EngB WS2065 182 COG0218 COG0218, Predicted GTPase General function prediction only 34557187 Common - THIAMIN-PHOSPHATE PYROPHOSPHORYLASE WS0788 195 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 34556523 Common - hypothetical protein WS0069 22 COG4866 COG4866, Uncharacterized conserved protein Function unknown 34556777 Common MURA UDP-N-acetylglucosamine 1-carboxyvinyltransferase WS0342 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 34556895 Common EFG elongation factor G WS0470 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 34558488 Common - PUTATIVE ABC TRANSPORTER, ATP-BINDING PROTEIN WS2214 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 34556647 Common lpxK tetraacyldisaccharide 4'-kinase WS0204 121 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 34558087 Common - hypothetical protein WS1780 3 None None None 34557198 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase WS0800 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 34557278 Common - hypothetical protein WS0888 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 34558072 Common - conserved hypothetical protein-Predicted ATPase related to phosphate starvation-inducible protein PhoH WS1765 192 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 34557610 Common leuS leucyl-tRNA synthetase WS1245 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34557796 Common - PUTATIVE ALDOLASE WS1452 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 34557247 Common - TWO-COMPONENT HYBRID SENSOR AND REGULATOR WS0852 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34558025 Common rplW 50S ribosomal protein L23 WS1714 56 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 34556766 Common - hypothetical protein WS0331 13 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 34558216 Common sdhC SUCCINATE DEHYDROGENASE SUBUNIT C WS1922 50 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 34556622 Common - hypothetical protein WS0174 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 34557150 Common - hypothetical protein WS0749 6 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 34557708 Common - hypothetical protein WS1352 124 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 34557067 Common YCHM SULFATE TRANSPORTER SULFATE TRANSPORTER FAMILY PROTEIN WS0651 164 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 34556904 Common NUOG NADH OXIDOREDUCTASE I WS0479 184 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 34557528 Nonpathogen - hypothetical protein WS1156 8 COG2014 COG2014, Uncharacterized conserved protein Function unknown 34557643 Common EFP elongation factor P WS1279 224 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 34558362 Common PTH peptidyl-tRNA hydrolase WS2078 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 34556855 Nonpathogen - hypothetical protein WS0427 7 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 34557787 Common HSDM_2 TYPE I RESTRICTION ENZYME (MODIFICATION SUBUNIT) WS1442 124 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 34556737 Common - hypothetical protein WS0301 7 None None None 34557097 Common - hypothetical protein WS0686 21 None None None 34556914 Nonpathogen - hypothetical protein WS0491 1 None None None 34558405 Common - PUTATIVE PROTEASE WS2122 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 34556883 Common PURF amidophosphoribosyltransferase WS0456 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 34556475 Common - PUTATIVE TWO-COMPONENT SENSOR WS0016 186 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34556467 Nonpathogen CYTB CYTB PROTEIN WS0008 1 None None None 34557878 Common - PHOSPHONATES TRANSPORT SYSTEM WS1550 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 34557310 Common - hypothetical protein WS0921 5 COG2863 COG2863, Cytochrome c553 Energy production and conversion 34556717 Common - PERMEASE OF ABC TRANSPORTER WS0280 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 34558192 Common aroC chorismate synthase WS1897 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 34558487 Common - SIGMA-54 INTERACTING PROTEIN WS2213 190 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 34557829 Common - hypothetical protein WS1492 38 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 34558031 Common - hypothetical protein WS1720 6 None None None 34558188 Common pyrB HOMOSERINE O-ACETYLTRANSFERASE PROTEIN WS1893 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 34557538 Common - NADP(H) OXIDOREDUCTASE WS1166 73 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 34556939 Common atpC F0F1 ATP synthase subunit epsilon WS0517 161 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 34557934 Common - hypothetical protein WS1616 4 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 34557429 Common - LUCIFERASE-ALPHA SUBUNIT WS1044 130 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 34557952 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase WS1636 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 34556968 Common - hypothetical protein WS0549 8 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 34557179 Nonpathogen - hypothetical protein WS0780 19 None None None 34557699 Common - PUTATIVE NA+/H+ ANTIPORTER WS1342 42 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 34556638 Common - ABC TRANSPORTER, ATP-BINDING PROTEIN WS0192 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 34558047 Common - UNDECAPRENYL PHOSPHATE N-ACETYLGLUCOSAMINYLTRANSFERASETRANSMEMBRANE PROTEIN WS1738 222 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 34556953 Nonpathogen - hypothetical protein WS0532 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 34558096 Common - conserved hypothetical protein-Predicted ATPase of the PP-loop superfamily implicated in cell cycle control WS1792 156 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 34558496 Common PGSA CDP-DIACYLGLYCEROL--PHOSPHATIDYLTRANSFERASE WS2223 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 34557321 Common - COENZYME F390 SYNTHETASE (FTSA-3) WS0932 122 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 34557420 Common livJ POTENTIAL LEU/ILE/VAL-BINDING PROTEIN PRECURSOR WS1035 109 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 34557172 Common - SENSORY PROTEIN, CONTAINING EAL-DOMAIN WS0772 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34556460 Common DNAN DNA polymerase III subunit beta WS0001 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 34556805 Common - hypothetical protein WS0372 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 34557899 Nonpathogen tonB hypothetical protein WS1574 1 None None None 34558104 Common flgG flagellar basal body rod protein FlgG WS1802 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 34557924 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein WS1603 241 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 34558040 Common - hypothetical protein WS1730 7 None None None 34557303 Common - DNR WS0913 117 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 34557088 Common - hypothetical protein WS0675 8 COG0795 COG0795, Predicted permeases General function prediction only 34556810 Common - PUTATIVE TWO-COMPONENT SENSOR WS0378 195 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34557455 Common ACCB PUTATIVE BIOTIN CARBOXYL CARRIER PROTEIN OF ACETYL-COA CARBOXYLASE WS1072 178 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 34556815 Common NRFI NRFI PROTEIN WS0383 83 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 34557885 Common - hypothetical protein WS1557 8 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 34558134 Common - hypothetical protein WS1835 2 None None None 34556582 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0133 7 None None None 34557754 Common NIFA TRANSCRIPTIONAL REGULATOR (NIFA FAMILY) WS1404 173 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 34557602 Common - hypothetical protein WS1237 3 None None None 34557609 Common - hypothetical protein WS1244 7 None None None 34556631 Common - hypothetical protein WS0185 7 None None None 34557592 Common HTPX heat shock protein HtpX WS1226 193 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 34557446 Common - hypothetical protein WS1063 184 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 34557652 Common PYCA acetyl-CoA carboxylase WS1289 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 34558171 Common - hypothetical protein WS1876 52 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 34558457 Common - hypothetical protein WS2181 40 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 34556853 Common tpiA triosephosphate isomerase WS0424 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 34557504 Common HSDR HSDR PROTEIN PROBABLE TYPE I RESTRICTION ENZYME RESTRICTIONCHAIN WS1129 145 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 34558015 Common rpsH 30S ribosomal protein S8 WS1703 227 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 34558178 Common - conserved hypothetical protein-Nucleotide binding protein WS1883 79 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 34557987 Common - NA-DRIVEN MULTIDRUG EFFLUX PROTEIN WS1674 180 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 34558436 Common hemH ferrochelatase WS2157 171 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 34556749 Common secG preprotein translocase subunit SecG WS0313 16 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 34558199 Common - XYLANASE/CHITIN DEACETYLASE WS1905 97 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 34556869 Common - INTEGRAL MEMBRANE PROTEIN (MVIN HOMOLOG) WS0442 190 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 34556961 Common - PUTATIVE TYPE II SECRETION SYSTEM D WS0541 143 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 34558449 Common - hypothetical protein WS2173 105 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 34556495 Common PGLB PGLB (PILIN GLYCOSYLATION PROTEIN PGLB) WS0038 134 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 34556569 Common RHPR RESPONSE TWO-COMPONENT REGULATOR WS0119 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34556656 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0213 191 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557576 Common - PUTATIVE MCP-TYPE SIGNAL TRANSDUCTION PROTEIN WS1209 103 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557820 Common - CYTOCHROME C BIOGENESIS PROTEIN (CCDA) WS1481 119 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 34558382 Common - PUTATIVE ABC TRANSPORTER, ATP-BINDING PROTEIN WS2099 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 34556862 Common - HIT FAMILY PROTEIN WS0435 106 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 34558003 Common rplQ 50S ribosomal protein L17 WS1691 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 34556874 Common - hypothetical protein WS0447 6 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 34557554 Common - hypothetical protein WS1185 37 COG2128 COG2128, Uncharacterized conserved protein Function unknown 34556729 Common CYNT CARBONIC ANYHYDRASE WS0293 149 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 34556497 Common WLAG PUTATIVE GALACTOSYLTRANSFERASE WS0040 214 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 34557852 Common tgt queuine tRNA-ribosyltransferase WS1519 228 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 34557564 Common MOEA2 PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN WS1195 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 34556486 Common FDHB PUTATIVE FORMATE DEHYDROGENASE IRON-SULFUR SUBUNIT WS0028 181 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34557763 Common - hypothetical protein WS1415 12 None None None 34556844 Common RHPS SENSOR KINASE OF TWO-COMPONENT REGULATORY SYSTEM WS0415 226 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34557444 Common - hypothetical protein WS1061 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 34557752 Common - hypothetical protein WS1402 21 None None None 34557330 Common - hypothetical protein WS0941 7 None None None 34556699 Common flgK flagellar hook-associated protein FlgK WS0259 112 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 34557020 Common - hypothetical protein WS0604 7 None None None 34557413 Common - glucose-6-phosphate isomerase WS1027 206 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 34557502 Common - ORF2 WS1127 41 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 34557191 Common HYPD HYDROGENASE PROTEIN WS0793 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 34558017 Common rplX 50S ribosomal protein L24 WS1705 203 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 34558156 Common MTH1856 SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) WS1860 164 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 34558282 Common AHPC ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT C WS1995 220 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 34557352 Common - hypothetical protein WS0964 200 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34557404 Nonpathogen topA hypothetical protein WS1017 3 None None None 34558251 Nonpathogen - hypothetical protein WS1963 1 None None None 34557995 Common HYDE HYDE PROTEIN WS1683 7 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 34556997 Common pyrB aspartate carbamoyltransferase catalytic subunit WS0580 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 34556795 Nonpathogen - hypothetical protein WS0362 1 None None None 34557235 Common SELB PUTATIVE SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR WS0839 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 34557876 Common CSTA CARBON STARVATION PROTEIN-Predicted membrane protein WS1548 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 34558181 Common hemL glutamate-1-semialdehyde aminotransferase WS1886 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 34556823 Common - hypothetical protein WS0392 6 None None None 34557831 Common eno phosphopyruvate hydratase WS1494 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 34558204 Common - GUANOSINE PENTAPHOSPHATE PHOSPHOHYDROLASE GPPA WS1910 184 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 34557903 Common hemC porphobilinogen deaminase WS1578 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 34556926 Common rpmA 50S ribosomal protein L27 WS0504 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 34558494 Common dapA dihydrodipicolinate synthase WS2221 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 34558407 Common GLNA GLUTAMINE SYNTHETASE WS2124 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 34557955 Common fliA flagellar biosynthesis sigma factor WS1639 103 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 34558371 Common - hypothetical protein WS2087 17 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 34557976 Common - TRANSMEMBRANE TRANSPORT PROTEIN-Predicted Co/Zn/Cd cation transport WS1661 203 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 34557495 Common - ALLOPHANATE HYDROLASE WS1119 46 None None None 34558435 Common - hypothetical protein WS2156 3 None None None 34557106 Nonpathogen - hypothetical protein WS0695 1 None None None 34557145 Common TNPA PUTATIVE TRANSPOSASE WS0742 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34557115 Common hydC hypothetical protein WS0705 30 COG3658 COG3658, Cytochrome b Energy production and conversion 34557052 Nonpathogen - hypothetical protein WS0636 1 None None None 34558094 Common CHEV_1 CHEMOTAXIS PROTEIN WS1787 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 34557532 Common - OLIGOPEPTIDE BINDING PROTEIN WS1160 193 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 34557725 Common - hypothetical protein WS1373 2 None None None 34556577 Common - PUTATIVE MCP-TYPE SIGNAL TRANSDUCTION PROTEIN WS0128 124 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556702 Nonpathogen - hypothetical protein WS0262 1 None None None 34557385 Common SELD1 SELENOPHOSPHATE SYNTHETASE WS0997 100 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 34558279 Common - NUCLEOSIDE DIPHOSPHATE KINASE WS1991 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 34558226 Common - hypothetical protein WS1934 59 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 34557928 Common - HYPOTHETICAL PROTEIN-AraC-type DNA-binding domain-containing WS1608 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 34556695 Common wlaE PUTATIVE GLYCOSYLTRANSFERASE WS0255 194 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 34558063 Common - hypothetical protein WS1756 5 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 34557866 Common - TRANSMEMBRANE PROTEIN WS1538 35 COG4269 COG4269, Predicted membrane protein Function unknown 34557217 Common lspA lipoprotein signal peptidase WS0819 126 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 34557017 Common - SODIUM/SOLUTE SYMPORTER, PUTATIVE WS0601 166 COG4147 DhlC, Predicted symporter General function prediction only 34558258 Common fliL flagellar basal body-associated protein FliL WS1970 11 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 34556540 Common - hypothetical protein WS0087 7 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 34556615 Common - conserved hypothetical protein CJ0172C WS0167 54 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 34557694 Common - hypothetical protein WS1336 20 None None None 34557009 Common - hypothetical protein WS0592 2 None None None 34556688 Common - ABC TRANSPORT SYSTEM ATP-BINDING PROTEIN WS0248 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 34557626 Common TNPA PUTATIVE TRANSPOSASE WS1262 150 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 34556946 Common SLYD PEPTIDYL-PROLYL ISOMERASE WS0525 138 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 34556979 Common GLNB P2-LIKE SIGNAL TRANSMITTER PROTEIN GLNB WS0560 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 34558327 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN-DRUG METABOLITE TRANSPORTER SUPERFAMILY WS2042 90 COG2510 COG2510, Predicted membrane protein Function unknown 34557801 Common - hypothetical protein WS1457 2 None None None 34556811 Common - hypothetical protein WS0379 4 None None None 34557679 Common - hypothetical protein WS1318 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 34556567 Common NRFC NRFC WS0117 167 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34557789 Common - hypothetical protein WS1444 25 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 34557483 Common - PARA PROTEIN WS1105 190 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 34556734 Common - hypothetical protein WS0298 161 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 34557131 Common - hypothetical protein WS0724 35 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 34557029 Common tdk thymidylate kinase WS0613 219 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 34558396 Common - hypothetical protein WS2113 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 34557728 Common CHEY CHEY AND CHEB GENES (CHEMOTAXIS PROTEIN) WS1376 222 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 34557175 Common NIFL NITROGEN FIXATION POSITIVE PROTEIN WS0775 183 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34556513 Common lpxA UDP-N-acetylglucosamine acyltransferase WS0059 169 COG1043 LpxA, Acyl- acyl carrier protein 34557095 Common - hypothetical protein WS0682 2 None None None 34557931 Common - PUTATIVE TRANSCRIPTION REGULATOR WS1612 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 34556967 Common rpsP 30S ribosomal protein S16 WS0548 208 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 34556772 Common - ENDOPEPTIDASE CLP ATP-BINDING CHAIN A WS0337 241 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 34558420 Common ARGB ACETYLGLUTAMATE KINASE WS2140 220 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 34556466 Common - hypothetical protein WS0007 42 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 34557393 Common MOEB MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEB WS1006 218 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 34557216 Common - PUTATIVE PHOSPHO-SUGAR MUTASE WS0818 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 34558410 Common - PUTATIVE TWO-COMPONENT SENSOR WS2127 192 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34557208 Common rho transcription termination factor Rho WS0810 209 COG1158 Rho, Transcription termination factor Transcription 34557146 Common MUTY A/G-SPECIFIC ADENINE GLYCOSYLASE WS0745 216 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 34558219 Nonpathogen - hypothetical protein WS1925 1 None None None 34556838 Common - NITROGEN REGULATORY PROTEIN P-II WS0409 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 34557222 Common - phosphoenolpyruvate synthase WS0826 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 34556508 Common WBGT PUTATIVE UDP-GLUCOSE 6-DEHYDROGENASE WS0054 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 34557156 Common - hypothetical protein WS0755 67 None None None 34558269 Common - sensor kinase of two-component regulatory system WS1981 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34557918 Common - hypothetical protein WS1597 31 COG3340 PepE, Peptidase E Amino acid transport and metabolism 34556982 Common - hypothetical protein WS0563 6 None None None 34558357 Common - conserved hypothetical protein-PUTATIVE Mg DEPENDENT DNase WS2073 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 34558335 Common CARA carbamoyl phosphate synthase small subunit WS2050 232 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 34558419 Common - hypothetical protein WS2139 2 None None None 34557838 Common TOPA DNA topoisomerase I WS1501 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 34557666 Common - hypothetical protein WS1305 22 COG2319 COG2319, FOG: WD40 repeat General function prediction only 34557040 Common LEUA 2-ISOPROPYLMALATE SYNTHASE WS0624 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 34556535 Common - nucleotide-binding protein WS0081 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 34557364 Common - hypothetical protein WS0976 13 COG3153 COG3153, Predicted acetyltransferase General function prediction only 34557126 Common - hypothetical protein WS0716 72 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 34557598 Common - PUTATIVE TONB-DEPENDENT RECEPTOR WS1232 99 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 34557859 Nonpathogen - hypothetical protein WS1528 1 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 34557608 Common - hypothetical protein WS1243 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34557169 Common - ACRIFLAVIN RESISTANCE A PRECURSOR WS0768 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 34557775 Common EXBB2 BIOPOLYMER TRANSPORT EXBB PROTEIN WS1429 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 34558477 Nonpathogen - hypothetical protein WS2202 7 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 34557076 Common - anaerobic C4-dicarboxylate transporter WS0661 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 34556779 Common - GGDEF DOMAIN PROTEIN WS0344 225 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 34557047 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase WS0631 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 34558093 Common - hypothetical protein WS1786 39 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 34557846 Common - hypothetical protein WS1513 6 None None None 34556740 Common - hypothetical protein WS0304 61 COG1565 COG1565, Uncharacterized conserved protein Function unknown 34556684 Common AMIA N-ACETYLMURAMOYL-L-ALANINE AMIDASE WS0243 180 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 34557328 Common - METHYL-ACC. CHEMOTAXIS SIGNAL TRANSDUCTION WS0939 106 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557769 Common - PUTATIVE TRANSMEMBRANE SENSOR WS1422 49 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 34558163 Common - TRANSPORT TRANSMEMBRANE PROTEIN-Phosphate/sulphate permeases WS1868 139 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 34556462 Common - 7-cyano-7-deazaguanine reductase WS0003 90 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 34557256 Nonpathogen - hypothetical protein WS0862 1 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 34558011 Common rplO 50S ribosomal protein L15 WS1699 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 34557757 Common - hypothetical protein WS1407 21 COG3603 COG3603, Uncharacterized conserved protein Function unknown 34558136 Common nuoI formate hydrogenlyase complex iron-sulfur subunit WS1837 196 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 34556760 Common maf Maf-like protein WS0325 73 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 34556488 Common - hypothetical protein WS0030 3 None None None 34556916 Common CREC hypothetical protein WS0493 14 COG2319 COG2319, FOG: WD40 repeat General function prediction only 34556643 Common glpC PUTATIVE IRON-SULFUR BINDING REDUCTASE WS0199 99 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 34558324 Common PGM phosphoglyceromutase WS2039 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 34557794 Common - ADP-HEPTOSE-LPS HEPTOSYLTRANSFERASE II (RFAF) WS1450 108 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 34557060 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCP WS0644 117 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557850 Common aroB 3-dehydroquinate synthase WS1517 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 34556533 Nonpathogen CYTB hypothetical protein WS0079 7 None None None 34556548 Common cheV hypothetical protein WS0095 88 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 34557271 Common truB tRNA pseudouridine synthase B WS0878 229 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 34556764 Common - POTASSIUM CHANNEL PROTEIN WS0329 55 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 34558345 Common DFP bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase WS2060 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 34557524 Nonpathogen - hypothetical protein WS1152 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 34557989 Common - conserved hypothetical protein-Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family WS1677 80 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 34557488 Common - ABC TRANSPORTER, PERMEASE PROTEIN WS1111 169 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 34556846 Common - PUTATIVE RIBOSOMAL PSEUDOURIDINE SYNTHASE WS0417 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 34556872 Common - PUTATIVE METHYLASE WS0445 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 34556800 Common - SIGNAL-TRANSDUCTION REGULATORY PROTEIN WS0367 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 34558346 Common - FLAA1 PROTEIN WS2061 193 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 34557586 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase WS1220 221 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 34556571 Common FCCC PUTATIVE TETRAHEME CYTOCHROME C WS0121 43 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 34558403 Common - hypothetical protein WS2120 4 None None None 34558481 Common - cysteine desulfurase WS2206 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 34557374 Common - OLIGOPEPTIDE ABC TRANSPORTER PERMEASE WS0986 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 34556653 Nonpathogen - hypothetical protein WS0210 1 None None None 34558260 Common - PUTATIVE ATP-DEPENDENT PROTEASE LA PROTEIN WS1972 218 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 34557510 Common hsdM TYPE I SITE-SPECIFIC DEOXYRIBONUCLEASE WS1136 162 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 34556857 Common POLA DNA polymerase I WS0430 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 34556789 Common COMEC DNA TRANSFER PROTEIN WS0355 18 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 34557290 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0900 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557038 Common - hypothetical protein WS0622 8 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 34557547 Common napG quinol dehydrogenase periplasmic component WS1177 63 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34556621 Nonpathogen - hypothetical protein WS0173 1 None None None 34557613 Common secD preprotein translocase subunit SecD WS1248 214 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 34557237 Common - COMPONENTS OF SENSORY TRANSDUCTION SYSTEM WS0841 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34557936 Nonpathogen - hypothetical protein WS1619 1 None None None 34556999 Common RESA CYTOCHROME C BIOGENESIS THIOREDOXIN WS0582 120 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 34558470 Common - HYPOTHETICAL PROTEIN-PROBABLE METHYL TRANSFERASE WS2195 42 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 34558108 Common MODD MOLYBDENUM TRANSPORT SYSTEM PROTEIN WS1807 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 34556521 Common - hypothetical protein WS0067 149 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 34557558 Common - PUTATIVE AMINOTRANSFERASE WS1189 205 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 34557396 Common - sulfate adenylyltransferase subunit 2 WS1009 152 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 34556897 Common NUOA NADH dehydrogenase subunit A WS0472 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 34557010 Common - hypothetical protein WS0593 15 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 34557718 Common - PUTATIVE TRANSPORT PROTEIN WS1365 108 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 34557467 Nonpathogen - hypothetical protein WS1087 2 None None None 34556562 Common prfB peptide chain release factor 2 WS0111 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 34556649 Common NADE NH(3)-DEPENDENT NAD(+) SYNTHETASE WS0206 229 COG0171 NadE, NAD synthase Coenzyme metabolism 34558422 Common - hypothetical protein WS2142 13 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 34557481 Common - hypothetical protein WS1103 5 None None None 34557594 Nonpathogen - hypothetical protein WS1228 1 None None None 34558075 Common DCUB anaerobic C4-dicarboxylate transporter WS1768 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 34557471 Common VIRB11 VIRB11 WS1092 228 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 34557423 Common - OLIGOENDOPEPTIDASE F (PEPF) WS1038 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 34558237 Common - hypothetical protein WS1946 23 None None None 34558023 Common rpsS 30S ribosomal protein S19 WS1712 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 34558214 Common SDHA SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT WS1920 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 34558388 Common flgH flagellar basal body L-ring protein WS2105 100 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 34557297 Common YTLC PUTATIVE TRANSPORTER WS0907 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 34556557 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ WS0105 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 34556506 Common WBCL TRSC WS0051 143 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 34557604 Common MFD TRANSCRIPTION-REPAIR COUPLING FACTOR WS1239 222 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 34556665 Common HEMG PROTOPORPHYRINOGEN OXIDASE WS0222 219 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 34557438 Common rpsO 30S ribosomal protein S15 WS1054 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 34558459 Common - hypothetical protein WS2183 15 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 34558450 Common - hypothetical protein WS2174 144 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34557578 Common - CIAB PROTEIN WS1211 6 None None None 34557770 Common - PUTATIVE RNA POLYMERASE SIGMA FACTOR WS1423 78 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 34557000 Common - UDP-GLUCOSE DEHYDROGENASE WS0583 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 34556971 Common rplS 50S ribosomal protein L19 WS0552 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 34558273 Nonpathogen - hypothetical protein WS1985 3 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 34556654 Common - hypothetical protein WS0211 3 None None None 34556628 Common CCOP CB-TYPE CYTOCHROME C OXIDASE SUBUNIT III WS0181 59 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 34558444 Common - hypothetical protein WS2167 10 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 34556868 Common - hypothetical protein WS0441 4 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 34557323 Common - PUTATIVE TWO-COMPONENT REGULATOR WS0934 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557650 Common - putative inner membrane protein translocase component YidC WS1286 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 34557454 Common dcd deoxycytidine triphosphate deaminase WS1071 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 34557561 Common - hypothetical protein WS1192 15 None None None 34557688 Common - PUTATIVE TWO-COMPONENT SENSOR WS1328 206 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 34558190 Common GUAB inositol-5-monophosphate dehydrogenase WS1895 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 34558057 Common - FERREDOXIN-TYPE OXIDOREDUCTASE WS1750 177 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 34556963 Common - PUTATIVE TYPE II PROTEIN SECRETION E WS0543 217 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 34557723 Common - PUTATIVE ABC-TRANSPORT SYSTEM PERMEASE PROTEIN WS1371 193 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 34558084 Common - hypothetical protein WS1777 7 None None None 34557536 Nonpathogen - hypothetical protein WS1164 4 None None None 34558049 Common - zinc transporter ZupT WS1740 102 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 34558186 Common - conserved hypothetical protein-Predicted amidohydrolase WS1891 24 COG0388 COG0388, Predicted amidohydrolase General function prediction only 34558197 Common - TRNA METHYLTRANSFERASE WS1903 32 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 34556801 Common - aspartate-semialdehyde dehydrogenase WS0368 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 34557019 Common PLSC PUTATIVE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE WS0603 175 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 34558124 Common AMAA MEMBRANE PROTEIN-Predicted permease WS1824 60 COG0628 PerM, Predicted permease General function prediction only 34556715 Common - BINDING PROTEIN COMPONENT ABC TRANSPORTER WS0278 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 34556739 Common - hypothetical protein WS0303 5 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 34557674 Common SERA D-3-PHOSPHOGLYCERATE DEHYDROGENASE WS1313 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 34558037 Common - SENSOR/RESPONSE REGULATOR HYBRID WS1727 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34557948 Common - hypothetical protein WS1632 17 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 34557741 Common NIFEN2 NIFEN2 WS1390 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 34557711 Common - hypothetical protein WS1355 11 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 34556700 Common - hypothetical protein WS0260 4 None None None 34558102 Common - INTEGRAL MEMBRANE PROTEIN WS1799 91 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 34556817 Common - hypothetical protein WS0385 106 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 34558005 Common rpsD 30S ribosomal protein S4 WS1693 246 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 34556821 Common - ABC-TYPE TRANSPORTER, ATPASE COMPONENT WS0390 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 34558498 Common - hypothetical protein WS2225 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 34556720 Common - PUTATIVE MCP-TYPE SIGNAL TRANSDUCTION PROTEIN WS0283 111 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557883 Common - S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE WS1555 140 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 34556469 Common - hypothetical protein WS0010 10 None None None 34556598 Common fliD flagellar capping protein WS0150 127 COG1345 FliD, Flagellar capping protein Cell motility and secretion 34556750 Common frr ribosome recycling factor WS0314 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 34556888 Common rplK 50S ribosomal protein L11 WS0463 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 34557664 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase WS1302 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 34556584 Common - hypothetical protein WS0136 111 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 34557980 Common flgC flagellar basal body rod protein FlgC WS1666 123 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 34557189 Common HYPB HYDROGENASE PROTEIN B WS0791 107 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 34556807 Common - hypothetical protein WS0374 56 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 34557993 Common - hypothetical protein WS1681 14 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 34557301 Common cfrA IRON-REGULATED COLICIN RECEPTOR WS0911 114 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 34556473 Common kpsF hypothetical protein WS0014 81 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 34558230 Common - PUTATIVE TWO-COMPONENT REGULATOR-CheY like receiver domain WS1939 126 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 34558109 Common modB PUTATIVE TRANSMEMBRANE PROTEIN WS1808 193 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 34557342 Common thiG thiazole synthase WS0954 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 34557756 Common PCTA TRANSDUCER (CHEMOTACTIC TRANSDUCER PCTA) WS1406 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556515 Common - hypothetical protein WS0061 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 34558461 Common WBFR WBFR PROTEIN WS2185 152 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 34557308 Common NOSD Nitrous oxidase accessory protein WS0919 50 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 34556774 Common - PUTATIVE ATP/GTP-BINDING PROTEIN WS0339 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 34557706 Common APT adenine phosphoribosyltransferase WS1350 171 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 34556595 Common - hypothetical protein WS0147 8 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 34557645 Common - CELL BINDING FACTOR 2 PRECURSOR MAJOR ANTIGEN PEB4A WS1281 160 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 34557957 Common - ATP-BINDING PROTEIN-ATPase involved in chromosome partitioning WS1641 237 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 34557054 Common - ABC TRANSPORTER (ATP-BINDING PROTEIN) WS0638 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 34558433 Common PETC UBIQUINOL CYTOCHROME C OXIDOREDUCTASE, CYTOCHROME C1 SUBUNIT WS2154 14 COG2857 CYT1, Cytochrome c1 Energy production and conversion 34557772 Common chuA OUTER MEMBRANE RECEPTOR FOR IRON-REGULATED COLICIN I RECEPTOR, PORIN,REQUIRES TONB GENE PRODUCT COLICIN I RECEPTOR WS1425 115 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 34557242 Nonpathogen - hypothetical protein WS0846 1 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 34558202 Common WAAM lipid A biosynthesis lauroyl acyltransferase WS1908 130 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 34557337 Common PSTS PERIPLASMIC PHOSPHATE BINDING PROTEIN WS0948 129 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 34556707 Nonpathogen - hypothetical protein WS0268 2 None None None 34556704 Common - hypothetical protein WS0265 68 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 34557531 Common - PUTATIVE ABC TRANSPORTER, PERMEASE PROTEIN WS1159 208 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 34557686 Nonpathogen - hypothetical protein WS1326 1 None None None 34556886 Common secE preprotein translocase subunit SecE WS0461 6 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 34557509 Common - hypothetical protein WS1135 17 None None None 34557459 Common - PUTATIVE TWO-COMPONENT RESPONSE REGULATOR WS1077 188 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 34556918 Common GRPE GRPE PROTEIN (HSP-70 COFACTOR) WS0495 228 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 34557108 Common - MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN WS0697 110 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557974 Common - hypothetical protein WS1659 15 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 34557864 Common - ZN-RIBBON-CONTAINING PROTEIN-Involved in phosphonate metabolism WS1535 104 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 34557133 Common - PUTATIVE INTEGRAL MEMBRANE PROTEIN WS0726 7 None None None 34557262 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase WS0868 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 34556663 Common TRPF ANTHRANILATE ISOMERASE WS0220 196 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 34557286 Common IMP OUTERMEMBRANE PERMEABILITY PROTEIN WS0896 106 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 34558065 Common flgE flagellar hook protein FlgE WS1758 128 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 34557158 Nonpathogen - hypothetical protein WS0757 12 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 34556813 Common fdhB PUTATIVE NITRITE REDUCTASE, FORMATE-DEPENDENT, FE-S CENTERS WS0381 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34556559 Nonpathogen MYO-1 hypothetical protein WS0107 1 None None None 34558176 Common - PUTATIVE PERIPLASMIC PROTEIN WS1881 55 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 34557566 Common MOAE POSSIBLE MOLYBDOPTERIN CONVERTING FACTOR, SUBUNIT 2 WS1197 16 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 34557167 Common - hypothetical protein WS0766 107 COG0640 ArsR, Predicted transcriptional regulators Transcription 34557500 Common - ORF2 PROTEIN WS1125 118 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 34557022 Common - hypothetical protein WS0606 105 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 34557007 Common - PUTATIVE TRANSMEMBRANE SENSOR WS0590 47 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 34557497 Common YVGW YVGW PROTEIN WS1121 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 34557406 Common - hypothetical protein WS1019 176 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 34558140 Common NQO8 HYDROGENASE-4 COMPONENT C .-.- WS1841 188 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 34557439 Common TONB_1 hypothetical protein WS1055 10 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 34556601 Common - hypothetical protein WS0153 25 COG4866 COG4866, Uncharacterized conserved protein Function unknown 34557973 Common - ATPASE-PP-loop superfamily WS1657 174 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 34557750 Common FRDA FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT WS1399 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 34557363 Common cheA HYBRID HISTIDINE KINASE WS0975 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34556608 Common - hypothetical protein WS0160 11 None None None 34557748 Common NIFB NIFB WS1397 95 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 34556723 Common - LINOCIN M18 WS0287 21 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 161760550 Common rpsB 30S ribosomal protein S2 WS0194 233 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 34558284 Common fliH flagellar assembly protein H WS1997 49 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 34557422 Common KEFB POTASSIUM-EFFLUX PROTEIN WS1037 203 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 34556697 Common CHEV_1 PUTATIVE CHEMOTAXIS PROTEIN WS0257 85 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 34558129 Common - hypothetical protein WS1830 44 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 34556459 Common dnaA chromosomal replication initiation protein WS0000 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 34557905 Common PROS prolyl-tRNA synthetase WS1580 243 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 34558446 Common - hypothetical protein WS2170 60 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 34556499 Common WLAF PUTATIVE INTEGRAL MEMBRANE PROTEIN POSSIBLE OLIGOSACCHARYLTRANSFERASE WS0043 7 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 34557452 Common oorB 2-oxoglutarate-acceptor oxidoreductase subunit OorB WS1069 111 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 34556995 Common fdhB IRON-SULFUR PROTEIN PRECURSOR WS0578 148 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 34558306 Common RIBD PUTATIVE RIBOFLAVIN-SPECIFIC DEAMINASE WS2019 199 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 34557841 Common - ENDONUCLEASE III WS1507 55 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 34558145 Common - SUPEROXIDE DISMUTASE WS1846 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 34557148 Common - hypothetical protein WS0747 72 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 34557074 Nonpathogen - hypothetical protein WS0659 1 None None None 34558479 Common - hypothetical protein WS2204 119 COG2855 COG2855, Predicted membrane protein Function unknown 34557128 Common - hypothetical protein WS0720 96 COG0778 NfnB, Nitroreductase Energy production and conversion 34557517 Common - hypothetical protein WS1145 3 None None None 34557154 Common ARSC ARSC WS0753 126 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 34556836 Common - ABC TRANSPORTER WS0407 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 34557836 Common RBN PUTATIVE RIBONUCLEASE BN WS1499 73 COG1295 Rbn, Predicted membrane protein Function unknown 34558359 Common RIBA riboflavin synthase subunit alpha WS2075 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 34556471 Common - PUTATIVE TWO-COMPONENT SENSOR WS0012 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34558333 Common BIOF 7-KETO-8-AMINOPELARGONIC ACID SYNTHETASE PUTATIVE 8-AMINO-7-OXONONANOATE SYNTHASE WS2048 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 34557273 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase WS0881 9 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 34558277 Common PLSX fatty acid/phospholipid synthesis protein WS1989 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 34557090 Common - hypothetical protein WS0677 61 COG2836 COG2836, Uncharacterized conserved protein Function unknown 34557490 Common - hypothetical protein WS1113 46 COG3665 COG3665, Uncharacterized conserved protein Function unknown 34557773 Common TONB2 hypothetical protein WS1426 19 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 34557117 Common - MOLYBDOPTERIN OXIDOREDUCTASE, MEMBRANE SUBUNIT WS0707 33 COG5557 COG5557, Polysulphide reductase Energy production and conversion 34556617 Common - hypothetical protein WS0169 6 None None None 34557817 Common - chlorohydrolase WS1477 16 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 34557857 Nonpathogen - hypothetical protein WS1525 6 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 34557069 Common - ALL5102 PROTEIN WS0653 47 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 34556560 Common - GGDEF FAMILY PROTEIN WS0108 225 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 34557206 Common - hypothetical protein WS0808 54 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 34558468 Common PAB1605 PUTATIVE ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZ WS2192 150 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 34557945 Common SUD SULFIDE DEHYDROGENASE PRECURSOR WS1629 90 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 34557056 Common - SENSOR KINASE CUSS WS0640 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 34557229 Nonpathogen uvrC hypothetical protein WS0833 1 None None None 34557395 Common - GTPASE, SULFATE ADENYLATE TRANSFERASE SUBUNIT 1 WS1008 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 34558246 Common - METHYL-ACCEPTING CHEMOTAXIS PROTEIN WS1956 75 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557240 Common PUTP SODIUM/PROLINE SYMPORTER WS0844 188 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 34556944 Common OMP18 LIPOPROTEIN PRECURSOR WS0522 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 34556579 Common ILVD dihydroxy-acid dehydratase WS0130 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 34557692 Common - CHEMOTAXIS SIGNAL TRANSDUCTION PROTEIN WS1333 121 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34557432 Common - MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN WS1047 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 34556954 Common PILT TWITCHING MOTILITY PROTEIN WS0533 216 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 34557848 Common - conserved hypothetical protein-2-methylthioadenine synthetase WS1515 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 34557313 Common - ABC TRANSPORTER, ATP-BINDING PROTEIN WS0924 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 34557933 Common - hypothetical protein WS1615 100 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 34557358 Common NRFH SMALL SUBUNIT OF CYTOCHROME C NITRITE REDUCTASE WS0970 39 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 34557141 Common - adenosine deaminase WS0737 103 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 34557295 Common - hypothetical protein WS0905 39 COG1309 AcrR, Transcriptional regulator Transcription 34557783 Nonpathogen - hypothetical protein WS1437 1 None None None 34558348 Common - hypothetical protein WS2063 5 None None None 34557214 Common prfA peptide chain release factor 1 WS0816 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 34557806 Common - PUTATIVE TWO-COMPONENT REGULATOR WS1463 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 34557635 Common HEFC RND PUMP PROTEIN WS1271 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 34557584 Common argH argininosuccinate lyase WS1218 234 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism