Enterococcus faecalis V583, complete genome NC_004668 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 29374836 Common - iron compound ABC transporter, substrate-binding protein EF0188 73 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 29376260 Common - hypothetical protein EF1708 19 COG3538 COG3538, Uncharacterized conserved protein Function unknown 29375930 Common - hydroxymethylglutaryl-CoA synthase EF1363 75 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 29375545 Common - transcriptional regulator, AraC family EF0962 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 29375984 Common - site-specific recombinase, phage integrase family EF1417 122 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29375692 Common pheT phenylalanyl-tRNA synthetase subunit beta EF1116 238 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 29376047 Common - hypothetical protein EF1480 4 None None None 29376725 Common - DNA-binding response regulator, AraC family EF2218 216 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 29377381 Common - UDP-N-acetylglucosamine 2-epimerase EF2917 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 29374838 Common - ferrichrome ABC transporter, permease protein EF0192 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 29376268 Common carB carbamoyl phosphate synthase large subunit EF1716 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 29377773 Common rnpA ribonuclease P EF3332 55 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 29377559 Pathogen - hypothetical protein EF3103 1 None None None 29376646 Pathogen - hypothetical protein EF2137 1 None None None 29377079 Common - ABC transporter, ATP-binding/permease protein EF2592 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29377436 Common phoZ alkaline phosphatase EF2973 85 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 29376852 Pathogen - hypothetical protein EF2351 1 None None None 29374878 Common rplQ 50S ribosomal protein L17 EF0234 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 29376779 Common - hypothetical protein EF2276 10 COG1289 COG1289, Predicted membrane protein Function unknown 29375382 Common - permease domain protein EF0792 18 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 29376877 Common - membrane-associated zinc metalloprotease, putative EF2380 215 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 29375336 Common - hypothetical protein EF0742 5 COG4835 COG4835, Uncharacterized protein conserved in bacteria Function unknown 29375220 Common - ornithine cyclodeaminase EF0616 100 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 29376113 Common hup DNA-binding protein HU EF1550 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 29375263 Common - hypothetical protein EF0664 12 None None None 29377552 Common - hydrolase, haloacid dehalogenase-like family EF3095 144 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 29377674 Common - hypothetical protein EF3227 4 None None None 29376521 Common - major tail protein, putative EF2005 8 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 29377415 Common - hypothetical protein EF2951 9 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 29374937 Common - copper-translocating P-type ATPase EF0298 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 29377341 Common accA acetyl-CoA carboxylase subunit alpha EF2875 174 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 29377181 Common - acetyltransferase, GNAT family EF2701 18 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 29377361 Pathogen - hypothetical protein EF2896 1 None None None 29376537 Pathogen - hypothetical protein EF2022 2 None None None 29375924 Common - transcriptional regulator, AraC family EF1357 123 COG4936 PocR, Predicted sensor domain Signal transduction mechanisms / Transcription 29376749 Pathogen - hypothetical protein EF2243 1 None None None 29377358 Common - hypothetical protein EF2893 2 None None None 29376351 Common lacD-2 tagatose 1,6-diphosphate aldolase EF1807 26 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 29377271 Common - ISEf1, transposase EF2800 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29375023 Common arcC-2 carbamate kinase EF0386 74 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 29375939 Common - CBS domain protein EF1372 31 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 29376759 Common - hypothetical protein EF2254 3 None None None 29375092 Common - PTS system, IIA component EF0461 68 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29376085 Common - cation-transporting ATPase, E1-E2 family EF1519 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 29376024 Common - minor head protein EF1457 20 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 29376039 Common - hypothetical protein EF1472 2 None None None 29375359 Common - hypothetical protein EF0766 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 29376149 Common - MutT/nudix family protein EF1587 42 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 29377269 Pathogen - hypothetical protein EF2797 1 None None None 29376415 Common - transcriptional regulator, Cro/CI family EF1886 8 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 29376859 Common purB adenylosuccinate lyase EF2361 240 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 29376752 Pathogen - transcriptional regulator EF2247 1 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29377545 Pathogen - hypothetical protein EF3088 1 None None None 29376785 Common - hypothetical protein EF2282 2 None None None 29374855 Common rpsS 30S ribosomal protein S19 EF0210 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 29376830 Common - hypothetical protein EF2329 5 None None None 29375840 Common nusA transcription elongation factor NusA EF1271 224 COG0195 NusA, Transcription elongation factor Transcription 29377601 Common - hypothetical protein EF3149 73 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 29374824 Common deoC deoxyribose-phosphate aldolase EF0174 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 29374732 Common - gls24 protein EF0079 32 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 29377354 Common glxR 2-hydroxy-3-oxopropionate reductase EF2889 193 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 29376015 Pathogen - hypothetical protein EF1448 1 None None None 29377284 Pathogen - major tail protein, phi13 family EF2815 2 None None None 29375227 Pathogen - hypothetical protein EF0625 1 None None None 29377688 Pathogen - hypothetical protein EF3244 1 None None None 29376992 Common - GcvH family protein EF2500 177 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 29376934 Common - celC-related protein EF2440 32 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 29375835 Pathogen - hypothetical protein EF1266 1 None None None 29377721 Common - hypothetical protein EF3278 15 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 29376403 Common - transposase, IS256 family EF1874 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29375006 Common - aspartate kinase EF0368 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 29376626 Pathogen - hypothetical protein EF2117 1 None None None 29375232 Common - glyoxalase family protein EF0630 37 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 29377021 Pathogen - hypothetical protein EF2532 1 None None None 29377590 Common - PTS system, IIA component EF3136 93 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29374992 Common - holin, putative EF0353 3 None None None 29375312 Common - hypothetical protein EF0716 10 None None None 29375426 Common - pyridoxal phosphate-dependent enzyme, putative EF0838 47 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 29377472 Common - hypothetical protein EF3011 17 None None None 29375813 Common - sugar-binding transcriptional regulator, LacI family EF1240 128 COG1609 PurR, Transcriptional regulators Transcription 29376512 Common cspC cold shock protein CspC EF1991 181 COG1278 CspC, Cold shock proteins Transcription 29374741 Common - diacylglycerol kinase catalytic domain protein EF0090 105 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 29376515 Pathogen - hypothetical protein EF1994 1 None None None 29374662 Common dnaA chromosomal replication initiator protein DnaA EF0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 29377754 Pathogen - hypothetical protein EF3313 1 None None None 29375680 Pathogen - hypothetical protein EF1104 1 None None None 29374721 Common - bacterial luciferase family protein EF0065 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 29375179 Pathogen - hypothetical protein EF0566 1 None None None 29376142 Common lexA LexA repressor EF1579 170 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 29375436 Common acpS holo-(acyl-carrier-protein) synthase EF0848 144 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 29377654 Common - adhesion lipoprotein EF3206 175 COG3443 COG3443, Predicted periplasmic or secreted protein General function prediction only 29377770 Common - DNA-binding response regulator EF3329 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376258 Common - aromatic amino acid aminotransferase EF1706 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 29375323 Common - putative lipid kinase EF0727 114 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 29375066 Common rhaA L-rhamnose isomerase EF0434 24 COG4806 RhaA, L-rhamnose isomerase Carbohydrate transport and metabolism 29376333 Common purK-1 phosphoribosylaminoimidazole carboxylase, ATPase subunit EF1786 202 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 29377748 Common - PTS system, sorbitol-specific IIC component EF3307 22 COG3730 SrlA, Phosphotransferase system sorbitol-specific component IIC Carbohydrate transport and metabolism 29377498 Pathogen - hypothetical protein EF3040 1 None None None 29376573 Common topB-1 DNA topoisomerase III EF2064 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 29376467 Common - hypothetical protein EF1941 6 None None None 29375117 Pathogen - hypothetical protein EF0489 1 None None None 29376465 Common - hypothetical protein EF1939 7 COG2364 COG2364, Predicted membrane protein Function unknown 29376960 Common - hypothetical protein EF2466 12 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29374689 Common - hypothetical protein EF0031 46 COG2898 COG2898, Uncharacterized conserved protein Function unknown 29376886 Pathogen - hypothetical protein EF2389 1 None None None 29377486 Common htrA serine protease DO EF3027 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 29375279 Common - DNA repair exonuclease family protein EF0682 86 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 29376291 Common ccpA catabolite control protein A EF1741 130 COG1609 PurR, Transcriptional regulators Transcription 29376899 Pathogen - hypothetical protein EF2404 1 None None None 29376072 Common - hypothetical protein EF1505 32 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 29376999 Common - transcriptional regulator, Cro/CI family EF2508 123 COG1396 HipB, Predicted transcriptional regulators Transcription 29375564 Common tlyA hemolysin A EF0982 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 29375610 Common - phosphorylase family protein EF1031 73 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 29375867 Common - hypothetical protein EF1299 15 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 29377188 Common - membran protein, putative EF2708 11 COG2261 COG2261, Predicted membrane protein Function unknown 29376437 Pathogen - hypothetical protein EF1909 1 None None None 29375515 Pathogen - hypothetical protein EF0931 1 None None None 29376050 Pathogen - hypothetical protein EF1483 1 None None None 29377330 Common - hypothetical protein EF2862 77 COG1434 COG1434, Uncharacterized conserved protein Function unknown 29374718 Common - 5'-nucleotidase family protein EF0062 141 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 29374980 Common - hypothetical protein EF0341 2 None None None 29376423 Common - hypothetical protein EF1895 5 None None None 29376363 Common - histidine kinase, putative EF1820 9 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 29376489 Common - hypothetical protein EF1967 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 29377405 Pathogen - hypothetical protein EF2941 1 None None None 29375591 Common - sigma-54 interaction domain protein EF1010 158 COG3933 COG3933, Transcriptional antiterminator Transcription 29375343 Pathogen - cell wall surface anchor family protein EF0750 1 None None None 29377584 Common - hypothetical protein EF3130 2 None None None 29376132 Common psr transcriptional regulator, PSR protein EF1569 62 COG1316 LytR, Transcriptional regulator Transcription 29376396 Common - sensor histidine kinase EF1863 155 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 29375145 Pathogen - hypothetical protein EF0519 1 None None None 29376639 Common - DnaD domain protein EF2130 7 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 29376815 Pathogen - hypothetical protein EF2313 2 None None None 29376744 Pathogen - lipoprotein, putative EF2237 1 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 29375664 Common - hypothetical protein EF1088 27 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 29375722 Common - DNA-directed RNA polymerase, delta subunit, putative EF1146 14 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 29375297 Common - hemolysin EF0700 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 29376188 Common - sensor histidine kinase EF1632 101 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 29376382 Common - polysaccharide deacetylase family protein EF1843 83 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 29377140 Common - phosphopantothenoylcysteine decarboxylase EF2656 235 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 29375917 Common - hypothetical protein EF1350 27 COG3548 COG3548, Predicted integral membrane protein Function unknown 29377019 Pathogen - hypothetical protein EF2530 1 None None None 29375496 Common - peptide ABC transporter, ATP-binding protein EF0912 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 29376566 Common - heptaprenyl diphosphate synthase, component II, putative EF2057 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 29375787 Common budA alpha-acetolactate decarboxylase EF1214 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 29375622 Common - hypothetical protein EF1043 4 None None None 29376170 Common ppaC putative manganese-dependent inorganic pyrophosphatase EF1611 59 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 29376528 Pathogen - hypothetical protein EF2013 1 None None None 29375742 Common - YitT family protein EF1166 56 COG1284 COG1284, Uncharacterized conserved protein Function unknown 29375665 Common - hypothetical protein EF1089 31 COG3152 COG3152, Predicted membrane protein Function unknown 29375729 Common - thermostable carboxypeptidase 1 EF1153 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 29376767 Common - gluconate 5-dehydrogenase EF2263 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29376734 Common - ABC transporter, ATP-binding/permease protein EF2227 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375775 Common - hypothetical protein EF1200 21 COG3610 COG3610, Uncharacterized conserved protein Function unknown 29376310 Common ftsE cell division ATP-binding protein FtsE EF1761 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 29375406 Common - PTS system, IID component EF0817 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29377086 Common - acyl carrier protein, putative EF2601 96 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 29377389 Common - cold-shock domain family protein EF2925 182 COG1278 CspC, Cold shock proteins Transcription 29377621 Common recA recombinase A EF3171 238 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 29377560 Common - ABC transporter, ATP-binding protein EF3104 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 29375563 Common ispA geranyltranstransferase EF0981 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 29376892 Common frr ribosome recycling factor EF2395 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 29377036 Common - hypothetical protein EF2547 2 None None None 29376909 Common phoH phoH-like protein EF2414 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 29374764 Pathogen - hypothetical protein EF0113 1 COG1475 Spo0J, Predicted transcriptional regulators Transcription 29377626 Common - hypothetical protein EF3176 42 COG3304 COG3304, Predicted membrane protein Function unknown 29374786 Pathogen - hypothetical protein EF0135 1 None None None 29375646 Common galM aldose 1-epimerase EF1068 90 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 29377173 Common - hypothetical protein EF2693 69 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 29376843 Common - hypothetical protein EF2342 3 None None None 29375078 Common - menaquinone-specific isochorismate synthase EF0447 222 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29375086 Common - PTS system, IIC component EF0455 38 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29377507 Common - phosphosugar-binding transcriptional regulator, RpiR family, putative EF3049 57 COG1737 RpiR, Transcriptional regulators Transcription 29376559 Common - conserved hypothetical protein TIGR00048 EF2048 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 29377466 Common - choloylglycine hydrolase family protein EF3005 50 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 29376399 Common - ABC transporter, ATP-binding protein EF1868 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29376179 Common - hypothetical protein EF1620 2 None None None 29375954 Common - hypothetical protein EF1387 4 None None None 29375286 Common - hypothetical protein EF0689 12 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 29377574 Common rpe ribulose-phosphate 3-epimerase EF3118 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 29376154 Common - ABC transporter, ATP-binding/permease protein EF1593 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29377319 Common - hypothetical protein EF2851 3 None None None 29377656 Common - ABC transporter, permease protein EF3208 155 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 29376682 Common - hypothetical protein EF2174 21 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 29376276 Common fhs formate--tetrahydrofolate ligase EF1725 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 29374948 Common - excisionase, putative EF0309 3 None None None 29377134 Common - spermidine/putrescine ABC transporter, permease protein EF2650 229 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 29376674 Pathogen - hypothetical protein EF2166 4 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 29376147 Common - transcriptional regulator, Fur family EF1585 208 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 29375026 Common - hypothetical protein EF0389 12 COG2056 COG2056, Predicted permease General function prediction only 29376329 Common purL phosphoribosylformylglycinamidine synthase II EF1782 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 29376360 Common - hypothetical protein EF1816 25 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 29376215 Common bkdD branched-chain alpha-keto acid dehydrogenase, E3 component, dihydrolipoamide dehydrogenase EF1661 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 29377216 Common - O-methyltransferase family protein EF2740 108 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 29375777 Common - hypothetical protein EF1202 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 29375063 Common - TRAP dicarboxylate transporter, DctM subunit EF0431 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 29375745 Common murAB UDP-N-acetylglucosamine 1-carboxyvinyltransferase EF1169 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 29375143 Common - 2-dehydropantoate 2-reductase EF0517 106 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 29375042 Common - PTS system, IIBC component EF0406 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 29374770 Common - phenazine biosynthesis protein PhzF family EF0119 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 29375017 Pathogen - hypothetical protein EF0380 1 None None None 29377312 Pathogen - hypothetical protein EF2844 1 None None None 29375069 Common - transcriptional regulator, AraC family EF0437 51 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 29375280 Common - hypothetical protein EF0683 25 COG4717 COG4717, Uncharacterized conserved protein Function unknown 29375946 Common alaS alanyl-tRNA synthetase EF1379 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29374956 Pathogen - transcriptional regulator, Cro/CI family EF0317 1 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 29376118 Common - YitT family protein EF1555 47 COG1284 COG1284, Uncharacterized conserved protein Function unknown 29377531 Common - signal peptidase I EF3073 171 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 29374796 Pathogen - hypothetical protein EF0145 1 None None None 29377320 Common - transcriptional regulator, Cro/CI family EF2852 22 COG1396 HipB, Predicted transcriptional regulators Transcription 29375831 Pathogen - hypothetical protein EF1262 1 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 29377695 Pathogen - hypothetical protein EF3252 1 None None None 29375208 Pathogen - hypothetical protein EF0603 1 None None None 29375624 Common pfk 6-phosphofructokinase EF1045 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 29374924 Common pyrD-1 dihydroorotate dehydrogenase 1A EF0285 124 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 29375770 Common - hypothetical protein EF1195 9 COG4863 COG4863, Uncharacterized protein conserved in bacteria Function unknown 29377727 Common - cystathionine gamma-synthase, putative EF3284 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 29376256 Common - sensory box histidine kinase EF1704 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 29377442 Common - PTS system, IIB component EF2979 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29376761 Common - PTS system, IIC component, putative EF2257 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29377703 Common - heptaprenyl diphosphate synthase, component II, putative EF3260 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 29374966 Common - hypothetical protein EF0327 2 None None None 29374873 Common infA translation initiation factor IF-1 EF0229 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 29374762 Common - oxidoreductase, zinc-binding EF0111 210 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 29374969 Common - SNF2 domain protein EF0330 107 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 29376166 Common - glycosyl hydrolase, family 1 EF1606 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 29375752 Common - hypothetical protein EF1176 8 None None None 29377154 Common - hypothetical protein EF2672 9 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 29375450 Common - glycine betaine/carnitine/choline ABC transporter, permease protein EF0862 167 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 29377646 Common - lipoprotein, YaeC family EF3198 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 29377152 Common ppnK inorganic polyphosphate/ATP-NAD kinase EF2670 232 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 29377295 Pathogen - hypothetical protein EF2826 2 None None None 29377235 Common - hypothetical protein EF2761 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 29377515 Pathogen - hypothetical protein EF3057 1 None None None 29375159 Common - N-acetylmannosamine-6-phosphate 2-epimerase EF0540 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 29376927 Common - phosphoglycerate mutase family protein EF2433 104 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 29377125 Common - glycine betaine/L-proline ABC transporter, ATP-binding subunit EF2641 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 29376322 Common - hypothetical protein EF1775 5 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 29376001 Common - DnaD domain protein EF1434 21 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 29375605 Common - CBS domain protein EF1025 38 COG0517 COG0517, FOG: CBS domain General function prediction only 29375793 Common - spermidine/putrescine ABC transporter, ATP-binding protein EF1220 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 29375505 Common - sulfate transporter family protein EF0921 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 29375629 Common - DNA-binding response regulator EF1050 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29375442 Common - signal peptidase I EF0854 162 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 29375898 Common - ABC transporter, ATP-binding protein EF1331 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 29375851 Pathogen - hypothetical protein EF1282 1 None None None 29374753 Common - transcriptional regulator, ArgR family EF0102 54 COG1438 ArgR, Arginine repressor Transcription 29377186 Common - RNA methyltransferase, TrmA family EF2706 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 29377452 Common - coenzyme A disulfide reductase EF2989 245 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 29374959 Pathogen - hypothetical protein EF0320 1 None None None 29376435 Common - maoC family protein EF1907 65 COG2030 MaoC, Acyl dehydratase Lipid metabolism 29375020 Common - protein FdrA/conserved hypothetical protein EF0383 24 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 29375367 Pathogen - gram positive anchor protein, putative EF0775 4 None None None 29375122 Pathogen - hypothetical protein EF0494 1 None None None 29376286 Common nfo endonuclease IV EF1736 104 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 29377146 Common - helicase, putative, RecD/TraA family EF2663 146 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 29376209 Common - 2-dehydropantoate 2-reductase EF1655 125 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 29375047 Common mltF PTS system, mannitol-specific IIA component EF0412 64 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 29377128 Common - diacylglycerol kinase catalytic domain protein EF2644 115 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 29377257 Common - hypothetical protein EF2785 17 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 29376920 Common - transcriptional regulator, GntR family EF2426 209 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 29375635 Pathogen - hypothetical protein EF1056 1 None None None 29377240 Common recR recombination protein RecR EF2766 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 29375875 Common grpE heat shock protein GrpE EF1307 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 29377613 Common prsA-2 ribose-phosphate pyrophosphokinase EF3163 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 29374692 Common - hypothetical protein EF0034 23 COG4283 COG4283, Uncharacterized conserved protein Function unknown 29377175 Pathogen - hypothetical protein EF2695 1 COG5116 RPN2, 26S proteasome regulatory complex component Posttranslational modification, protein turnover, chaperones 29376240 Pathogen - hypothetical protein EF1686 1 None None None 29376700 Common rfbB dTDP-glucose 4,6-dehydratase EF2192 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 29376871 Common - hypothetical protein EF2373 8 COG5353 COG5353, Uncharacterized protein conserved in bacteria Function unknown 29376694 Pathogen - hypothetical protein EF2186 1 None None None 29375887 Common - hypothetical protein EF1319 6 None None None 29377249 Common thiE thiamine-phosphate pyrophosphorylase EF2776 185 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 29375975 Common - ABC transporter, ATP-binding protein EF1408 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 29375172 Common - PTS system, IIA component EF0555 74 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29376820 Common - peptidase, M23/M37 family EF2318 201 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 29376411 Common - hypothetical protein EF1882 18 COG4734 ArdA, Antirestriction protein General function prediction only 29376618 Pathogen - hypothetical protein EF2109 1 None None None 29377306 Common - DNA replication protein DnaC, putative EF2838 39 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 29377372 Common - glycosyl transferase, group 2 family protein EF2908 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29377429 Common - hypothetical protein EF2965 30 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 29376026 Common - hypothetical protein EF1459 3 None None None 29376867 Pathogen - hypothetical protein EF2369 1 None None None 29374709 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase EF0051 211 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 29375575 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase EF0993 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 29376956 Common - hypothetical protein EF2462 11 COG4476 COG4476, Uncharacterized protein conserved in bacteria Function unknown 29375292 Common - PTS system, IIA component EF0695 64 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 29375716 Common gloA lactoylglutathione lyase EF1140 129 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 29376388 Pathogen - hypothetical protein EF1850 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29375873 Common - coproporphyrinogen III oxidase EF1305 211 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 29374845 Common rpsG 30S ribosomal protein S7 EF0199 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 29376247 Common - KH domain protein EF1693 50 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 29375375 Common metK S-adenosylmethionine synthetase EF0784 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 29376236 Common - hypothetical protein EF1682 11 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 29376319 Common - hypothetical protein EF1772 6 None None None 29374998 Common sugE-1 sugE protein EF0359 83 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 29375465 Common - dephospho-CoA kinase, putative EF0880 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 29375730 Common - DNA replication protein DnaD, putative EF1154 22 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 29376883 Common - hypothetical protein EF2386 2 None None None 29374947 Common - hypothetical protein EF0308 2 None None None 29374791 Pathogen - hypothetical protein EF0140 1 None None None 29376063 Common - V-type ATPase, subunit C EF1496 11 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 29376552 Pathogen - hypothetical protein EF2041 1 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 29375895 Common - transcriptional regulator, GntR family EF1328 151 COG2188 PhnF, Transcriptional regulators Transcription 29376832 Pathogen - hypothetical protein EF2331 1 None None None 29376104 Common - hypothetical protein EF1541 24 COG3601 COG3601, Predicted membrane protein Function unknown 29377228 Common nrdD anaerobic ribonucleoside triphosphate reductase EF2754 101 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 29375528 Common - extracellular protein, putative EF0944 23 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 29376707 Common - ribonuclease BN, putative EF2199 101 COG1295 Rbn, Predicted membrane protein Function unknown 29375175 Common - polysaccharide biosynthesis family protein EF0559 32 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 29377069 Common - putative chlorohydrolase/aminohydrolase EF2582 149 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 29375247 Common - NAD-dependent epimerase/dehydratase family protein EF0646 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 29376601 Pathogen - hypothetical protein EF2092 1 None None None 29374894 Common - N-acetylmuramoyl-L-alanine amidase EF0252 66 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 29377045 Common - cation transporter EF2558 96 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 29376676 Common - licD1 protein, putative EF2168 14 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 29376059 Pathogen - V-type ATPase, subunit F EF1492 1 None None None 29376509 Pathogen - hypothetical protein EF1988 1 None None None 29376718 Common - conserved hypothetical protein TIGR01655 EF2211 7 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 29377457 Common - hypothetical protein EF2995 41 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 29376101 Common - integrase/recombinase XerD, putative EF1537 232 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29375481 Common - preprotein translocase, YajC subunit, putative EF0897 12 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 29374742 Common - hypothetical protein EF0091 7 COG3711 BglG, Transcriptional antiterminator Transcription 29376978 Common - ABC transporter, ATP-binding protein EF2486 248 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 29377508 Common tag-2 DNA-3-methyladenine glycosylase I EF3050 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 29374726 Common - lipoprotein, putative EF0071 32 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 29375214 Common - hypothetical protein EF0609 19 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 29375540 Common - glycosyl hydrolase, family 65 EF0957 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 29376971 Common - hypothetical protein EF2478 19 None None None 29375129 Pathogen - lipoprotein, putative EF0501 1 None None None 29376589 Common - lipoprotein, YaeC family EF2080 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 29375169 Common - PTS system, IIC component EF0552 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29375494 Common - peptide ABC transporter, permease protein EF0910 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 29375137 Common - hypothetical protein EF0509 8 None None None 29376941 Common - DNA internalization-related competence protein ComEC/Rec2 EF2447 127 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 29376210 Common - transcriptional regulator, LysR family EF1656 187 COG0583 LysR, Transcriptional regulator Transcription 29376739 Common - ABC transporter, permease protein EF2232 149 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 29375698 Common rph ribonuclease PH/Ham1 protein EF1122 243 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 29377112 Common - teichoic acid glycosylation protein, putative EF2627 13 COG2246 COG2246, Predicted membrane protein Function unknown 29375983 Common pgi glucose-6-phosphate isomerase EF1416 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 29377229 Common nrdG anaerobic ribonucleoside-triphosphate reductase activating protein EF2755 56 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 29375768 Common vicR DNA-binding response regulator VicR EF1193 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29377095 Common atpA F0F1 ATP synthase subunit alpha EF2610 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 29376531 Common - portal protein EF2016 8 None None None 29376167 Common - cardiolipin synthetase, putative EF1608 152 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 29376306 Common - phosphate ABC transporter, permease protein EF1757 229 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 29377324 Common rpmG-3 ribosomal protein L33 EF2856 83 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 29376827 Common - group II intron reverse transcriptase maturase EF2326 89 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 29377062 Common arcC-4 carbamate kinase EF2575 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 29375167 Common - xylose repressor, putative EF0550 151 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 29377564 Common - peptide ABC transporter, permease protein EF3108 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 29375900 Common - ABC transporter, ATP-binding protein EF1333 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 29376582 Common prsA-1 ribose-phosphate pyrophosphokinase EF2073 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 29376986 Common cdsA phosphatidate cytidylyltransferase EF2494 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 29376596 Pathogen - holin EF2087 1 None None None 29376120 Common dapB dihydrodipicolinate reductase EF1557 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 29377160 Common trpS tryptophanyl-tRNA synthetase EF2679 223 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375105 Common feoA ferrous iron transport protein A EF0475 58 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 29375470 Common - hypothetical protein EF0885 6 COG1289 COG1289, Predicted membrane protein Function unknown 29376710 Common - tspO protein, putative EF2202 42 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 29377477 Common - hypothetical protein EF3016 53 None None None 29376929 Common - PTS system, IIBC components EF2435 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29377103 Common - carboxylesterase precursor, putative EF2618 22 COG1647 COG1647, Esterase/lipase General function prediction only 29375139 Common nuc-1 thermonuclease precursor EF0511 58 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 29376458 Common - oxidoreductase, pyridine nucleotide-disulfide family EF1932 220 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 29376948 Common - hypothetical protein EF2454 8 COG3679 COG3679, Uncharacterized conserved protein Function unknown 29375412 Common - acetyltransferase, GNAT family EF0824 25 COG0456 RimI, Acetyltransferases General function prediction only 29376663 Common - hypothetical protein EF2154 12 COG4720 COG4720, Predicted membrane protein Function unknown 29374915 Common - ada regulatory protein, putative EF0275 149 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 29377422 Common - transcriptional regulator, LysR family EF2958 162 COG0583 LysR, Transcriptional regulator Transcription 29377117 Common - IS256, transposase EF2632 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29376722 Common - hypothetical protein EF2215 5 COG3832 COG3832, Uncharacterized conserved protein Function unknown 29377667 Common - hypothetical protein EF3220 4 None None None 29375731 Common nth endonuclease III EF1155 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 29375602 Pathogen - hypothetical protein EF1022 1 None None None 29376453 Common - hypothetical protein EF1926 3 COG4915 XpaC, 5-bromo-4-chloroindolyl phosphate hydrolysis protein General function prediction only 29377076 Common manA mannose-6-phosphate isomerase, class I EF2589 50 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 29375673 Pathogen - hypothetical protein EF1097 1 None None None 29376444 Common - GTPase EngB EF1916 188 COG0218 COG0218, Predicted GTPase General function prediction only 29374779 Pathogen - hypothetical protein EF0128 1 None None None 29376390 Pathogen - hypothetical protein EF1853 1 None None None 29375357 Pathogen - hypothetical protein EF0764 1 None None None 29375474 Common - hypothetical protein EF0889 5 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 29375008 Common - septation ring formation regulator EzrA EF0370 18 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 29377611 Pathogen - hypothetical protein EF3160 1 None None None 29375225 Pathogen - hypothetical protein EF0622 1 None None None 29376087 Common sigA RNA polymerase sigma factor RpoD EF1522 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 29376125 Common - 3-deoxy-7-phosphoheptulonate synthase EF1562 187 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 29375258 Common - phage SPO1 DNA polymerase-related protein, putative EF0659 144 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 29375371 Pathogen - MutT/nudix family protein EF0780 1 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 29377183 Common - transcriptional regulator EF2703 62 COG1316 LytR, Transcriptional regulator Transcription 29377356 Common - glycosyl transferase, group 1 family protein EF2891 142 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 29375502 Common - hypothetical protein EF0918 30 COG3759 COG3759, Predicted membrane protein Function unknown 29376962 Common - transcriptional regulator, Cro/CI family EF2469 5 COG1396 HipB, Predicted transcriptional regulators Transcription 29375094 Common sodA superoxide dismutase, Mn EF0463 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 29376836 Common - hypothetical protein EF2335 17 None None None 29377213 Common - exonuclease EF2736 138 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 29375050 Common - hypothetical protein EF0415 45 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 29375057 Common - 2-dehydro-3-deoxygluconokinase, putative EF0424 122 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 29377041 Common hemK hemK protein EF2553 224 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 29376750 Pathogen - hypothetical protein EF2244 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29376932 Common - PTS system, IIA component EF2438 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 29376724 Common - alpha-1,2-mannosidase, putative EF2217 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 29375237 Common nhaC-2 Na+/H+ antiporter EF0636 51 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 29376476 Common - phosphosugar-binding protein EF1951 214 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 29376578 Pathogen - hypothetical protein EF2069 1 None None None 29376017 Common - positive control factor, putative EF1450 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29377084 Common - PTS system, beta-glucoside-specific IIABC component EF2598 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29374853 Common rplW ribosomal protein L23 EF0208 212 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 29375230 Common - PTS system, IIA component, putative EF0628 30 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29377597 Common - phosphosugar-binding transcriptional regulator, RpiR family EF3144 89 COG1737 RpiR, Transcriptional regulators Transcription 29375880 Common - S1 RNA binding domain protein EF1312 150 COG2183 Tex, Transcriptional accessory protein Transcription 29376037 Common - hypothetical protein EF1470 4 None None None 29375500 Common rplT 50S ribosomal protein L20 EF0916 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 29377599 Pathogen - hypothetical protein EF3146 1 None None None 29375961 Common - hypothetical protein EF1394 44 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 29376564 Common - oxidoreductase, pyridine nucleotide-disulfide family EF2055 203 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 29376538 Pathogen - hypothetical protein EF2023 1 None None None 29376571 Pathogen - hypothetical protein EF2062 1 None None None 29377742 Common - hypothetical protein EF3301 4 None None None 29376323 Pathogen - hypothetical protein EF1776 1 None None None 29377522 Common pnpA polynucleotide phosphorylase/polyadenylase EF3064 239 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 29377642 Common - antiholin-like protein LrgB EF3193 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 29374935 Common napA Na+/H+ antiporter EF0296 216 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 29375256 Common - transcriptional regulator, DeoR family EF0657 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 29374834 Common deoD-1 purine nucleoside phosphorylase EF0186 143 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 29374806 Pathogen - hypothetical protein EF0156 2 None None None 29374722 Common ruvA Holliday junction DNA helicase RuvA EF0066 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 29375547 Common - hypothetical protein EF0964 43 COG1694 MazG, Predicted pyrophosphatase General function prediction only 29376692 Pathogen - hypothetical protein EF2184 1 None None None 29375306 Common ptsH phosphocarrier protein HPr EF0709 143 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 29377310 Pathogen - hypothetical protein EF2842 1 None None None 29377474 Pathogen - hypothetical protein EF3013 2 COG3711 BglG, Transcriptional antiterminator Transcription 29376358 Common - drug resistance transporter, EmrB/QacA family protein EF1814 227 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29377569 Common recG ATP-dependent DNA helicase RecG EF3113 226 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 29376045 Common - hypothetical protein EF1478 4 None None None 29375033 Common - hypothetical protein EF0397 7 COG3247 HdeD, Uncharacterized conserved protein Function unknown 29377368 Common - hypothetical protein EF2904 38 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 29377676 Pathogen - hypothetical protein EF3232 1 None None None 29376954 Common - GTP-binding protein TypA EF2460 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 29376939 Common - 2-dehydropantoate 2-reductase EF2445 121 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 29377394 Common - hypothetical protein EF2930 9 COG0398 COG0398, Uncharacterized conserved protein Function unknown 29376969 Common - penicillin-binding protein 4 EF2476 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 29377691 Pathogen - hypothetical protein EF3248 1 None None None 29377698 Common - thiamin biosynthesis lipoprotein ApbE, putative EF3255 133 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 29376777 Common - transcriptional regulator, GntR family EF2273 56 COG2188 PhnF, Transcriptional regulators Transcription 29375538 Common - aldose 1-epimerase, putative EF0955 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 29377438 Common - hypothetical protein EF2975 15 None None None 29375338 Common - sodium/dicarboxylate symporter family protein EF0744 151 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 29377162 Common - hydrolase, haloacid dehalogenase-like family EF2681 104 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 29377226 Common - permease protein, putative EF2751 19 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 29375331 Common - amidase EF0737 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 29377339 Common - GTPase of unknown function EF2873 46 COG1161 COG1161, Predicted GTPases General function prediction only 29375687 Common - signal peptidase I EF1111 182 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 29377399 Common - xanthine/uracil permeases family protein EF2935 135 COG2252 COG2252, Permeases General function prediction only 29376772 Common - hypothetical protein EF2268 8 None None None 29375727 Common - cell division protein DivIVA, putative EF1151 20 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 29376737 Pathogen - hypothetical protein EF2230 1 None None None 29376091 Common gap-1 glyceraldehyde 3-phosphate dehydrogenase EF1526 218 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 29377713 Common gor glutathione reductase EF3270 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 29375345 Common - hypothetical protein EF0752 7 None None None 29377739 Common - chromosome partitioning protein ParB family EF3298 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 29376787 Pathogen - hypothetical protein EF2284 1 None None None 29377024 Common - nucleotidyltransferase domain protein EF2535 6 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 29377554 Common rnc ribonuclease III EF3097 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 29376912 Common - transcriptional regulator, Fur family EF2417 140 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 29377346 Common fabF-2 3-oxoacyl-(acyl carrier protein) synthase II EF2880 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29374982 Common - conserved hypothetical protein TIGR01725 EF0343 4 None None None 29376780 Pathogen - hypothetical protein EF2277 5 None None None 29376524 Pathogen - ribosomal protein L23, putative EF2008 1 None None None 29377322 Common - ion transporter, putative EF2854 123 None None None 29376523 Pathogen - hypothetical protein EF2007 1 None None None 29376262 Common - transcriptional regulator, LysR family EF1710 187 COG0583 LysR, Transcriptional regulator Transcription 29376140 Common folA dihydrofolate reductase EF1577 145 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 29376806 Common - transcriptional regulator, Cro/CI family EF2304 2 COG1396 HipB, Predicted transcriptional regulators Transcription 29377017 Common - transcriptional regulator, Cro/CI family EF2528 8 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 29375199 Common - hypothetical protein EF0587 2 None None None 29376860 Common purK-2 phosphoribosylaminoimidazole carboxylase, ATPase subunit EF2362 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 29375662 Pathogen - hypothetical protein EF1085 1 None None None 29376130 Common aroK shikimate kinase EF1567 205 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 29375184 Common - DNA-binding response regulator EF0571 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376630 Pathogen - hypothetical protein EF2121 1 None None None 29375720 Common - lipoate-protein ligase A family protein, putative EF1144 12 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 29376384 Pathogen - hypothetical protein EF1846 1 None None None 29375299 Common - hypothetical protein EF0702 6 None None None 29375498 Common infC translation initiation factor IF-3 EF0914 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 29376430 Common - glyoxylase family protein EF1902 14 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 29377142 Common - FemAB family protein EF2658 23 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 29377741 Common gidB glucose-inhibited division protein B EF3300 200 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 29375791 Common - spermidine/putrescine ABC transporter, permease protein EF1218 216 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 29375765 Common - hypothetical protein EF1190 8 None None None 29375518 Common - hydrolase, TatD family EF0934 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 29375554 Common - phosphate-starvation-inducible protein PsiE EF0971 2 COG3223 COG3223, Predicted membrane protein Function unknown 29375915 Common - glucan 1,6-alpha-glucosidase, putative EF1348 154 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 29374811 Pathogen - hypothetical protein EF0161 1 None None None 29376312 Common yfiA ribosomal subunit interface protein EF1764 174 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 29376668 Common glnR regulatory protein GlnR EF2160 64 COG0789 SoxR, Predicted transcriptional regulators Transcription 29376875 Common - DNA polymerase III, alpha subunit, Gram-positive type EF2378 218 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 29374918 Common - HD domain protein EF0279 61 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 29376689 Common - glycosyl transferase, group 2 family protein EF2181 168 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29374971 Common - hypothetical protein EF0332 10 None None None 29377547 Common - isochorismatase family protein EF3090 90 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 29377197 Common rplK ribosomal protein L11 EF2719 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 29375923 Common lpdA dihydrolipoamide dehydrogenase EF1356 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 29374788 Common - nucleotidyltransferase domain protein EF0137 10 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 29377769 Common - transcriptional regulator, GntR family EF3328 121 COG1802 GntR, Transcriptional regulators Transcription 29374911 Common arb 6-phospho-beta-glucosidase EF0271 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 29375273 Common - glycine betaine/carnitine/choline ABC transporter, glycine betaine/carnitine/choline-binding protein EF0675 101 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 29376010 Common - hypothetical protein EF1443 2 None None None 29374861 Common rplN ribosomal protein L14 EF0216 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 29374987 Common - tail protein EF0348 56 COG5412 COG5412, Phage-related protein Function unknown 29377387 Common - hypothetical protein EF2923 11 COG5503 COG5503, Uncharacterized conserved small protein Function unknown 29374712 Pathogen - hypothetical protein EF0054 1 None None None 29376727 Common - hypothetical protein EF2220 6 COG5578 COG5578, Predicted integral membrane protein Function unknown 29377608 Common - transcriptional regulator, GntR family EF3156 112 COG2188 PhnF, Transcriptional regulators Transcription 29374903 Common - hypothetical protein EF0262 224 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 29375229 Pathogen - hypothetical protein EF0627 1 None None None 29375001 Common - chitin binding protein, putative EF0362 28 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 29375404 Common - PTS system, IIAB components EF0815 74 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29377760 Common citF citrate lyase, alpha subunit EF3319 28 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 29377055 Common - aminotransferase, class V EF2568 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 29375329 Common - hypothetical protein EF0734 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 29376164 Common scrR-1 sucrose operon repressor ScrR EF1604 128 COG1609 PurR, Transcriptional regulators Transcription 29376782 Common - hypothetical protein EF2279 6 None None None 29375414 Common - transcriptional regulator, PemK family EF0826 48 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 29375434 Common - ATP-dependent RNA helicase, DEAD/DEAH box family EF0846 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 29375115 Pathogen - hypothetical protein EF0487 1 None None None 29375869 Common - cell division protein, FtsW/RodA/SpovE family EF1301 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 29376976 Common - hypothetical protein EF2484 43 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 29376219 Common - hypothetical protein EF1665 9 None None None 29376177 Common eutH ethanolamine utilization protein EutH EF1618 18 COG3192 EutH, Ethanolamine utilization protein Amino acid transport and metabolism 29375318 Common ligA DNA ligase, NAD-dependent EF0722 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 29376888 Common - NifU family protein EF2391 181 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 29376510 Common hemH ferrochelatase EF1989 166 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 29377011 Pathogen - hypothetical protein EF2522 1 None None None 29375036 Common - hypothetical protein EF0400 27 COG3817 COG3817, Predicted membrane protein Function unknown 29374669 Common ssb-1 single-strand binding protein EF0008 215 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 29377413 Pathogen - hypothetical protein EF2949 1 None None None 29376906 Common dgkA diacylglycerol kinase EF2411 47 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 29376335 Common - SPFH domain/Band 7 family protein EF1789 103 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 29376890 Common - hypothetical protein EF2393 182 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 29376405 Common - lipoprotein, NLP/P60 family EF1876 131 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 29376253 Common - hypothetical protein EF1701 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 29375535 Common - acetyltransferase, GNAT family EF0951 64 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 29375320 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C EF0724 162 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 29377119 Common groES chaperonin, 10 kDa EF2634 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 29377317 Common - hypothetical protein EF2849 4 None None None 29377070 Common - hypothetical protein EF2583 46 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 29375424 Common - hypothetical protein EF0836 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 29376338 Common - hypothetical protein EF1792 3 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 29375216 Pathogen - hypothetical protein EF0611 1 None None None 29375993 Pathogen - vrlI protein, putative EF1426 1 None None None 29377586 Common - hypothetical protein EF3132 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 29375147 Pathogen - hypothetical protein EF0523 1 None None None 29375507 Common - transcriptional regulator, LysR family EF0923 184 COG0583 LysR, Transcriptional regulator Transcription 29377652 Common - cobalamin synthesis protein/P47K family protein EF3204 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 29375509 Pathogen - hypothetical protein EF0925 1 None None None 29376115 Pathogen - hypothetical protein EF1552 1 None None None 29377277 Pathogen - hypothetical protein EF2806 1 None None None 29376637 Common - hypothetical protein EF2128 12 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 29375882 Common - aminotransferase AlaT EF1314 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 29375572 Common - cell division protein EF0990 3 COG4839 FtsL, Protein required for the initiation of cell division Cell division and chromosome partitioning 29374960 Pathogen - hypothetical protein EF0321 1 None None None 29377488 Common - PTS system, IID component EF3029 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29376709 Common - flavodoxin EF2201 88 COG0716 FldA, Flavodoxins Energy production and conversion 29376487 Common - transcriptional regulator, SorC family EF1965 22 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 29375579 Common ftsZ cell division protein FtsZ EF0997 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 29375588 Common - hypothetical protein EF1006 3 None None None 29375468 Common dnaI primosomal protein DnaI EF0883 36 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 29376810 Pathogen - hypothetical protein EF2308 1 None None None 29375932 Common - hypothetical protein EF1365 164 COG0628 PerM, Predicted permease General function prediction only 29376021 Common - terminase, small subunit, internal deletion EF1454 6 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 29376590 Common - ABC transporter, permease protein EF2081 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 29376817 Common - hypothetical protein EF2315 2 None None None 29377156 Common pepF oligoendopeptidase F,plasmid EF2674 85 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 29375972 Common trx thioredoxin EF1405 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 29376742 Common - glucuronyl hydrolase, putative EF2235 21 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 29376653 Pathogen - lipoprotein, putative EF2144 1 None None None 29376925 Common - chlorohydrolase family protein EF2431 153 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 29375402 Common - glycosyl hydrolase, family 35 EF0813 27 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 29377706 Pathogen - hypothetical protein EF3263 1 None None None 29377058 Common - hypothetical protein EF2571 117 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 29375953 Common - formate/nitrite transporter family protein EF1386 94 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 29376345 Common - PTS system, IIA component EF1801 64 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29377123 Common - ABC transporter, ATP-binding protein EF2639 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 29377632 Pathogen - hypothetical protein EF3182 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 29376763 Common - phosphosugar-binding transcriptional regulator, putative EF2259 24 COG1737 RpiR, Transcriptional regulators Transcription 29376577 Common - multidrug resistance protein, putative EF2068 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29375245 Common - transcriptional regulator, LysR family EF0644 185 COG0583 LysR, Transcriptional regulator Transcription 29376917 Common - transcriptional regulator, ArsR family EF2423 191 COG0640 ArsR, Predicted transcriptional regulators Transcription 29377517 Common - transcriptional regulator, TetR family EF3059 17 COG1309 AcrR, Transcriptional regulator Transcription 29377237 Common - hypothetical protein EF2763 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 161511184 Common - peptidase EF2578 185 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 29377644 Common - response regulator EF3196 211 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 29376469 Pathogen - hypothetical protein EF1944 1 None None None 29375858 Common - tail protein, putative EF1289 4 COG4722 COG4722, Phage-related protein Function unknown 29375654 Common - streptomycin 3''-adenylyltransferase, putative EF1076 14 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 29376441 Common - conserved hypothetical protein TIGR00278 EF1913 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 29375754 Common cscK fructokinase EF1179 120 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 29376197 Common - conserved hypothetical protein TIGR00023 EF1643 170 COG0344 COG0344, Predicted membrane protein Function unknown 29374875 Common rpsM 30S ribosomal protein S13 EF0231 245 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 29376003 Pathogen - hypothetical protein EF1436 1 None None None 29376550 Common - hypothetical protein EF2039 2 None None None 29377280 Common - minor structural protein EF2811 6 COG4926 PblB, Phage-related protein Function unknown 29375671 Pathogen - hypothetical protein EF1095 1 None None None 29375877 Pathogen - hypothetical protein EF1309 1 None None None 29375611 Common drrC daunorubicin resistance protein EF1032 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 29375763 Common - hydrolase, haloacid dehalogenase family EF1188 109 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 29377720 Common - cytosine permease, putative EF3277 68 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 29377297 Pathogen - hypothetical protein EF2829 1 None None None 29377255 Common galE-2 UDP-glucose 4-epimerase EF2783 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 29375373 Common rpoN RNA polymerase factor sigma-54 EF0782 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 29376284 Common - hypothetical protein EF1734 15 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 29375045 Pathogen - hypothetical protein EF0409 1 None None None 29375051 Common - hypothetical protein EF0417 50 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 29374973 Common - portal protein EF0334 6 None None None 29377149 Common - ribosomal RNA large subunit methyltransferase A, putative EF2666 61 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 29374755 Common arcA arginine deiminase EF0104 56 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 29376672 Common - hypothetical protein EF2164 8 None None None 29375637 Common - universal stress protein family EF1058 22 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 29377329 Common aadK aminoglycoside 6-adenylyltransferase EF2861 10 None None None 29377265 Common - hypothetical protein EF2793 8 COG3152 COG3152, Predicted membrane protein Function unknown 29375809 Common - acetyl xylan esterase, putative EF1236 19 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 29374773 Pathogen - hypothetical protein EF0122 1 None None None 29377136 Common - spermidine/putrescine ABC transporter, ATP-binding subunit EF2652 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 29376274 Common lspA lipoprotein signal peptidase EF1723 169 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 29375708 Common - CBS domain protein EF1132 26 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 29377081 Common - transcriptional regulator, TetR family EF2594 25 COG1309 AcrR, Transcriptional regulator Transcription 29375643 Pathogen - hypothetical protein EF1065 1 None None None 29375648 Common galE-1 UDP-glucose 4-epimerase EF1070 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 29375107 Pathogen - hypothetical protein EF0477 1 None None None 29375219 Common - transposase, IS200 family EF0615 68 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 29375597 Common - PTS system, IIB component EF1017 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 29376563 Common - cell division protein, FtsK/SpoIIIE family EF2052 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 29377130 Common - glycerate kinase, putative EF2646 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 29377206 Common nusG transcription antitermination protein NusG EF2729 215 COG0250 NusG, Transcription antiterminator Transcription 29374863 Common rplE 50S ribosomal protein L5 EF0218 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 29377501 Common - PTS system, IIC component EF3043 40 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29374950 Pathogen - hypothetical protein EF0311 1 None None None 29377006 Common - conjugal transfer protein, putative EF2517 12 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 29376217 Common ptb branched-chain phosphotransacylase EF1663 139 COG0280 Pta, Phosphotransacetylase Energy production and conversion 29376549 Pathogen - hypothetical protein EF2038 1 None None None 29376943 Common comEA competence protein comEA EF2449 133 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 29376446 Common - hypothetical protein EF1918 57 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 29375566 Common recN DNA repair protein RecN EF0984 207 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 29377139 Common - phosphopantothenate--cysteine ligase EF2655 151 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 29376680 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EF2172 190 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 29376702 Common rfbA glucose-1-phosphate thymidylyltransferase EF2194 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 29375206 Common - transcriptional regulator, TetR family EF0600 12 COG1309 AcrR, Transcriptional regulator Transcription 29377199 Common sdhB-2 L-serine dehydratase, iron-sulfur-dependent, beta subunit EF2721 128 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 29376220 Pathogen - hypothetical protein EF1666 1 None None None 29375670 Common - sortase family protein EF1094 17 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 29375150 Pathogen - cylL-S protein EF0526 1 None None None 29375991 Pathogen - hypothetical protein EF1424 1 None None None 29376849 Common - hypothetical protein EF2348 71 COG0433 COG0433, Predicted ATPase General function prediction only 29375649 Common galT galactose-1-phosphate uridylyltransferase EF1071 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 29376196 Common - iron compound ABC transporter, iron compound-binding protein EF1641 156 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 29375327 Common argF-2 putrescine carbamoyltransferase EF0732 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 29376191 Common - propanol dehydrogenase PduQ, putative EF1635 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 29376152 Common - transcriptional regulator, AraC family EF1591 156 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 29375944 Common - ATP-dependent RNA helicase, DEAD/DEAH box family EF1377 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 29374728 Common - transcriptional regulator, Crp/Fnr family EF0074 19 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 29375409 Common rplY 50S ribosomal protein L25/general stress protein Ctc EF0820 171 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 29375351 Common - cadmium-translocating P-type ATPase EF0758 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 29376457 Common - hypothetical protein EF1931 7 None None None 29375428 Common - carbohydrate kinase, pfkB family EF0840 63 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 29376304 Common - phosphate ABC transporter, ATP-binding protein EF1755 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 29376451 Pathogen - hypothetical protein EF1923 1 None None None 29376506 Pathogen - hypothetical protein EF1985 1 None None None 29377424 Common - ribose transporter protein RbsD EF2960 45 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 29375774 Common - hypothetical protein EF1199 6 COG3689 COG3689, Predicted membrane protein Function unknown 29377603 Common - hypothetical protein EF3151 94 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 29374798 Pathogen - hypothetical protein EF0147 1 None None None 29375981 Common - hypothetical protein EF1414 145 COG2081 COG2081, Predicted flavoproteins General function prediction only 29376074 Pathogen - hypothetical protein EF1507 1 None None None 29376792 Pathogen - hypothetical protein EF2289 1 None None None 29375135 Pathogen - hypothetical protein EF0507 1 None None None 29376712 Common - hypothetical protein EF2205 29 None None None 29376984 Common - glycosyl transferase, group 2 family protein EF2492 150 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29377462 Common - protease synthase and sporulation negative regulatory protein pai 1 EF3001 48 COG0456 RimI, Acetyltransferases General function prediction only 29375797 Common - transcriptional regulator, Cro/CI family EF1224 9 None None None 29374822 Common - sugar-binding transcriptional regulator, LacI family EF0172 129 COG1609 PurR, Transcriptional regulators Transcription 29376428 Common rimM 16S rRNA processing protein RimM EF1900 183 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 29376829 Common - TraG family protein EF2328 64 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 29376421 Pathogen - hypothetical protein EF1893 1 None None None 29374734 Common - hypothetical protein EF0081 12 COG2261 COG2261, Predicted membrane protein Function unknown 29376498 Common prmA ribosomal protein L11 methyltransferase EF1976 179 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 29376661 Common - cobalt transport family protein EF2152 57 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 29374867 Common rplR 50S ribosomal protein L18 EF0223 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 29377101 Common smpB SsrA-binding protein EF2616 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 29377469 Common - hypothetical protein EF3008 39 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 29377445 Common - phosphoglycerate mutase family protein EF2982 168 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 29376381 Common - HD domain protein EF1841 39 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 29375076 Common menB naphthoate synthase EF0445 180 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 29375120 Common - hypothetical protein EF0492 2 None None None 29375630 Common - sensor histidine kinase EF1051 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 29376227 Common - ABC transporter, ATP-binding protein EF1673 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29374674 Common purA adenylosuccinate synthetase EF0014 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 29375284 Common - HIT family protein EF0687 228 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 29375472 Common - glycosyl transferase, group 2 family protein EF0887 202 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29374917 Common tag-1 DNA-3-methyladenine glycosylase I EF0278 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 29375391 Pathogen - hypothetical protein EF0802 1 None None None 29376348 Common - PTS system, IIB component EF1804 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29375444 Common - aldo/keto reductase family protein EF0856 49 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 29377662 Common - ATP-dependent helicase, DEAH-box family, putative EF3214 160 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 29375099 Common - LemA family protein EF0468 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 29377535 Common - hypothetical protein EF3078 8 COG4493 COG4493, Uncharacterized protein conserved in bacteria Function unknown 29375418 Common - hypothetical protein EF0830 11 None None None 29376206 Common - DNA processing protein DprA, putative EF1652 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 29376533 Common - hypothetical protein EF2018 10 None None None 29375909 Common - transcriptional regulator, Mar family EF1342 12 COG1846 MarR, Transcriptional regulators Transcription 29377292 Common - terminase, large subunit, putative EF2823 43 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 29376008 Pathogen - hypothetical protein EF1441 1 None None None 29375604 Common ppdK pyruvate phosphate dikinase EF1024 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 29377254 Common - galactose-1-phosphate uridylyltransferase EF2782 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 29375170 Common - PTS system, IID component EF0553 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29377407 Pathogen - hypothetical protein EF2943 1 None None None 29376127 Common aroC chorismate synthase EF1564 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 29376808 Common - hypothetical protein EF2306 5 None None None 29377246 Common - major facilitator family transporter EF2773 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29377370 Common - ABC transporter, permease protein EF2906 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 29377455 Common - major facilitator family transporter EF2992 151 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 29374843 Common rpiA ribose-5-phosphate isomerase A EF0197 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 29377177 Common - hypothetical protein EF2697 9 COG4915 XpaC, 5-bromo-4-chloroindolyl phosphate hydrolysis protein General function prediction only 29375573 Common pbpC penicillin-binding protein C EF0991 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 29376994 Common - cell division protein, FtsW/RodA/SpoVE family EF2502 205 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 29376616 Pathogen - hypothetical protein EF2107 1 None None None 29376139 Common thyA thymidylate synthase EF1576 144 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 29376896 Common - acetyltransferase, GNAT family EF2399 51 COG0456 RimI, Acetyltransferases General function prediction only 29375889 Common - permease domain protein EF1321 79 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 29376885 Pathogen - hypothetical protein EF2388 1 None None None 29375718 Common - hydrolase, haloacid dehalogenase-like family EF1142 150 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 29374703 Common cysS cysteinyl-tRNA synthetase EF0045 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376317 Pathogen - hypothetical protein EF1770 1 None None None 29376103 Common - conserved hypothetical protein TIGR00281 EF1539 143 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 29377335 Common - hypothetical protein EF2868 91 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 29375587 Common - iron-dependent repressor EF1005 101 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 29375822 Pathogen - hypothetical protein EF1250 1 None None None 29375463 Common polA DNA polymerase I EF0878 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 29375526 Common - ABC transporter, ATP-binding/permease protein EF0942 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375483 Common - hypothetical protein EF0899 2 None None None 29376605 Common - tail protein EF2096 19 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 29377737 Common - translation-associated GTPase EF3296 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 29376800 Common vanYB D-alanyl-D-alanine carboxypeptidase EF2297 45 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 29376238 Common - DegV family protein, putative EF1684 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 29377529 Pathogen - hypothetical protein EF3071 1 None None None 29376065 Common - V-type ATP synthase subunit A EF1498 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 29375455 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase EF0868 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 29374885 Common brnQ branched-chain amino acid transport system II carrier protein EF0243 51 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 29376603 Pathogen - hypothetical protein EF2094 1 None None None 29377043 Common tdK thymidine kinase EF2555 96 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 29377615 Common maf maf protein EF3165 196 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 29377639 Pathogen - hypothetical protein EF3189 1 None None None 29377628 Common - succinyl-diaminopimelate desuccinylase EF3178 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 29374744 Pathogen - cell wall surface anchor family protein EF0093 2 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 29376376 Common lacA galactose-6-phosphate isomerase subunit LacA EF1835 124 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 29374904 Common - hypothetical protein EF0263 215 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 29374804 Common - hypothetical protein EF0154 5 None None None 29375755 Common - hypothetical protein EF1180 10 None None None 29374699 Common - PIN domain protein EF0041 47 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 29376614 Pathogen - hypothetical protein EF2105 1 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 29375786 Common - acetolactate synthase EF1213 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 29376106 Common fer ferredoxin EF1543 9 COG1141 Fer, Ferredoxin Energy production and conversion 29376057 Pathogen - hypothetical protein EF1490 1 None None None 29376230 Common - transcriptional regulator, GntR family EF1676 85 COG1725 COG1725, Predicted transcriptional regulators Transcription 29374926 Common efp elongation factor P EF0287 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 29377493 Common - transcriptional regulator, GntR family EF3034 141 COG2188 PhnF, Transcriptional regulators Transcription 29376246 Common - hypothetical protein EF1692 2 COG4803 COG4803, Predicted membrane protein Function unknown 29377468 Common - hypothetical protein EF3007 9 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 29376542 Pathogen - hypothetical protein EF2028 1 None None None 29377308 Common - hypothetical protein EF2840 5 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 29375802 Common - hypothetical protein EF1229 5 None None None 29375380 Common - ABC transporter, ATP-binding/permease protein EF0790 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375398 Common - hypothetical protein EF0809 5 COG2261 COG2261, Predicted membrane protein Function unknown 29377520 Common mreC rod shape-determining protein MreC EF3062 149 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 29375893 Common - transcriptional regulator, TetR family EF1326 48 COG1309 AcrR, Transcriptional regulator Transcription 29376176 Common - hypothetical protein EF1617 17 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 29374858 Common rplP 50S ribosomal protein L16 EF0213 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 29374921 Common fabI enoyl-(acyl carrier protein) reductase EF0282 218 COG0623 FabI, Enoyl- acyl-carrier-protein 29377533 Pathogen - hypothetical protein EF3075 2 None None None 29377685 Common - abortive phage resistance protein, putative EF3241 6 None None None 29375421 Common - hypothetical protein EF0833 11 None None None 29375544 Common - pyrroline-5-carboxylate reductase, putative EF0961 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 29376485 Common pgk phosphoglycerate kinase EF1963 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 29377567 Common acpP acyl carrier protein EF3111 207 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29375301 Common - lipoprotein, putative EF0704 3 None None None 161511185 Common obgE GTPase ObgE EF1527 249 COG0536 Obg, Predicted GTPase General function prediction only 29375995 Pathogen - hypothetical protein EF1428 1 None None None 29377541 Common - iron compound ABC transporter, permease protein EF3084 141 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 29375862 Common ply-1 endolysin EF1293 8 COG5632 COG5632, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 29376023 Common - conserved hypothetical protein TIGR01555 EF1456 19 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 29376080 Common - pheromone binding protein EF1513 193 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29375979 Pathogen - hypothetical protein EF1412 1 None None None 29377757 Common - malic enzyme family protein EF3316 202 COG0281 SfcA, Malic enzyme Energy production and conversion 29375803 Pathogen - hypothetical protein EF1230 1 None None None 29377159 Common - hypothetical protein EF2678 20 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 29375218 Pathogen - hypothetical protein EF0613 1 None None None 29375037 Common pcp pyrrolidone-carboxylate peptidase EF0401 56 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 29376548 Common - antirepressor, putative EF2037 26 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 29376213 Common bkdB branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit EF1659 174 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 29375684 Common - oxidoreductase, putative EF1108 168 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 29376643 Pathogen - hypothetical protein EF2134 1 None None None 29377244 Common - hypothetical protein EF2770 16 COG4721 COG4721, Predicted membrane protein Function unknown 29376705 Common - glycosyl transferase, group 2 family protein EF2197 116 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 29375368 Pathogen - hypothetical protein EF0776 2 None None None 29376819 Pathogen - hypothetical protein EF2317 1 None None None 29377750 Common srlM putative transcriptional activator SrlM EF3309 32 COG3711 BglG, Transcriptional antiterminator Transcription 29375757 Common luxS S-ribosylhomocysteinase EF1182 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 29376838 Pathogen - hypothetical protein EF2337 1 None None None 29376784 Pathogen - hypothetical protein EF2281 6 None None None 29374996 Common - hypothetical protein EF0357 68 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 29377344 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase EF2878 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 29374783 Common - hypothetical protein EF0132 2 None None None 29376002 Common - recombination protein U, putative EF1435 15 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 29377201 Common - hypothetical protein EF2723 35 COG2362 DppA, D-aminopeptidase Amino acid transport and metabolism 29375295 Common - acetyltransferase, GNAT family EF0698 84 COG2153 ElaA, Predicted acyltransferase General function prediction only 29376278 Common ebsa ebsA protein EF1727 2 None None None 29376387 Pathogen - hypothetical protein EF1849 5 None None None 29376556 Common comG2 competence protein EF2045 19 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 29375149 Pathogen - cylL-L protein EF0525 1 None None None 29375891 Common - hypothetical protein EF1324 2 None None None 29374697 Common - deoxyuridine 5`-triphosphate nucleotidohydrolase, putative EF0039 144 COG0756 Dut, dUTPase Nucleotide transport and metabolism 29375552 Common - hypothetical protein EF0969 17 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 29376251 Common - transcriptional regulator, MerR family EF1699 134 COG0789 SoxR, Predicted transcriptional regulators Transcription 29377231 Common - conserved hypothetical protein TIGR00245 EF2757 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 29377482 Common - sodium:dicarboxylate symporter family protein EF3022 156 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 29377556 Common - IS256, transposase EF3100 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29376635 Common - hypothetical protein EF2126 2 None None None 29377120 Pathogen - hypothetical protein EF2636 1 None None None 29374717 Common glmU UDP-N-acetylglucosamine pyrophosphorylase EF0059 238 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 29375970 Common - hypothetical protein EF1403 9 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 29376412 Pathogen - hypothetical protein EF1883 5 None None None 29376511 Pathogen - hypothetical protein EF1990 1 None None None 29376895 Common rpsB 30S ribosomal protein S2 EF2398 247 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 29376747 Common - site-specific recombinase, phage integrase family EF2240 111 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29374831 Common - hypothetical protein EF0183 17 COG3548 COG3548, Predicted integral membrane protein Function unknown 29375701 Common - putative L-ascorbate 6-phosphate lactonase EF1125 62 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 29375060 Common - hypothetical protein EF0428 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 29375726 Common - hypothetical protein EF1150 11 COG4474 COG4474, Uncharacterized protein conserved in bacteria Function unknown 29376633 Common - methyltransferase, putative EF2124 10 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 29375379 Common - ABC transporter, ATP-binding/permease protein EF0789 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29376562 Common - transcriptional regulator, GntR family EF2051 83 COG2188 PhnF, Transcriptional regulators Transcription 29375276 Common - acetyltransferase, GNAT family EF0678 115 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 29375806 Common - ABC transporter, permease protein EF1233 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 29375504 Common - hypothetical protein EF0920 40 COG2320 GrpB, Uncharacterized conserved protein Function unknown 29375814 Pathogen - hypothetical protein EF1241 1 None None None 29376479 Common - sigma-54 dependent DNA-binding response regulator EF1955 160 COG3933 COG3933, Transcriptional antiterminator Transcription 29376111 Common rpsA 30S ribosomal protein S1 EF1548 227 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 29374736 Pathogen - hypothetical protein EF0083 1 None None None 29375568 Common - cation transporter EF0986 86 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 29376123 Common - hypothetical protein EF1560 2 None None None 29375668 Common - cell wall surface anchor family protein EF1092 9 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29375193 Common - ABC transporter, ATP-binding protein EF0581 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 29374942 Common - phage integrase EF0303 85 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29375669 Common - cell wall surface anchor family protein EF1093 12 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29377446 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit, putative EF2983 210 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 29377145 Common - choline binding protein EF2662 11 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 29377609 Common - glycosyl hydrolase, family 65 EF3157 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 29376138 Common - ABC transporter, ATP-binding protein EF1575 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 29375310 Common - hypothetical protein EF0714 4 None None None 29375401 Common - glucuronyl hydrolase, putative EF0812 20 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 29374965 Pathogen - hypothetical protein EF0326 1 None None None 29375189 Common - adhesion lipoprotein EF0577 174 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 29375197 Common rpsN 30S ribosomal protein S14 EF0585 200 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 29377016 Pathogen - hypothetical protein EF2527 1 None None None 29374666 Common gyrB DNA gyrase, B subunit EF0005 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 29376541 Common - hypothetical protein EF2027 5 None None None 29375943 Common - hypothetical protein EF1376 7 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 29376433 Pathogen - hypothetical protein EF1905 1 None None None 29376035 Common - hypothetical protein EF1468 3 None None None 29375638 Common - hypothetical protein EF1059 47 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 29377060 Common - xanthine/uracil permease family protein EF2573 128 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 29377082 Common gmk-1 guanylate kinase EF2595 201 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 29376470 Common - hypothetical protein EF1945 42 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 29374972 Pathogen - conserved hypothetical protein TIGR01630 EF0333 1 None None None 29374876 Common rpsK 30S ribosomal protein S11 EF0232 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 29377138 Common - alcohol dehydrogenase, zinc-containing EF2654 154 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 29375084 Common - OsmC/Ohr family protein EF0453 104 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 29377067 Common - dihydropyrimidinase EF2580 207 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 29376624 Common - transcriptional regulator, ArpU family EF2115 3 None None None 29377606 Common - hypothetical protein EF3154 4 None None None 29375251 Common - hypothetical protein EF0652 2 None None None 29376303 Common - PhoU family protein EF1754 194 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 29375783 Common - response regulator EF1210 211 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 29375362 Common - hypothetical protein EF0769 12 None None None 29375003 Common - hypothetical protein EF0365 23 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 29375818 Common - hypothetical protein EF1246 28 COG2707 COG2707, Predicted membrane protein Function unknown 29375696 Common - amino acid ABC transporter, ATP-binding protein EF1120 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 29375386 Common - type 2 phosphatidic acid phosphatase family protein EF0796 105 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 29375211 Common - Dps family protein EF0606 114 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 29377432 Pathogen - cell wall surface anchor family protein EF2968 1 None None None 29375967 Common - cadmium-translocating P-type ATPase EF1400 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 29374673 Common dnaB replicative DNA helicase EF0013 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 29376847 Common - hypothetical protein EF2346 5 None None None 29375253 Common - sugar-binding transcriptional regulator, LacI family EF0654 125 COG1609 PurR, Transcriptional regulators Transcription 29377336 Common - HD domain protein EF2870 42 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 29375586 Common zwf glucose-6-phosphate 1-dehydrogenase EF1004 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 29376264 Common pyrE orotate phosphoribosyltransferase EF1712 118 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 29375950 Common - hypothetical protein EF1383 4 COG3326 COG3326, Predicted membrane protein Function unknown 29376904 Common - DNA repair protein RecO, putative EF2409 56 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 29374807 Pathogen - hypothetical protein EF0157 1 None None None 29376937 Common rpsT ribosomal protein S20 EF2443 154 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 29376775 Common - PTS system, IIB component EF2271 39 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29376222 Common - transcriptional regulator, MarR family EF1668 91 COG1846 MarR, Transcriptional regulators Transcription 29375531 Common - hydrolase, haloacid dehalogenase-like family EF0947 119 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 29376731 Common - cell wall surface anchor family protein EF2224 24 None None None 29376190 Common - propanediol utilization protein PduU EF1634 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 29375707 Common araD L-ribulose-5-phosphate 4-epimerase EF1131 97 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 29374857 Common rpsC 30S ribosomal protein S3 EF0212 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 29375935 Common - hypothetical protein EF1368 21 None None None 29374813 Pathogen - lipoprotein, putative EF0163 1 None None None 29377583 Common - D-alanyl-D-alanine carboxypeptidase EF3129 148 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 29377008 Pathogen - hypothetical protein EF2519 2 None None None 29377732 Common - sensor histidine kinase EF3290 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 29376855 Common - hypothetical protein EF2354 8 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 29377211 Common - oxidoreductase, Gfo/Idh/MocA family EF2734 155 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 29377392 Common - FolC family protein EF2928 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 29377677 Common - Dps family protein EF3233 127 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 29376812 Pathogen - hypothetical protein EF2310 1 None None None 29376492 Common aspS aspartyl-tRNA synthetase EF1970 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375685 Common - iron-sulfur cluster binding protein EF1109 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 29377384 Common - ABC transporter, ATP-binding/permease protein EF2920 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29377411 Pathogen - hypothetical protein EF2947 1 None None None 29377670 Pathogen - hypothetical protein EF3223 3 None None None 29374864 Common rpsN 30S ribosomal protein S14 EF0219 198 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 29377627 Common - hypothetical protein EF3177 4 None None None 29374800 Pathogen - hypothetical protein EF0150 1 None None None 29374928 Common - cysteine synthase B, putative EF0289 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 29375014 Pathogen - hypothetical protein EF0376 2 None None None 29376714 Common - DNA-binding protein, Fis family EF2207 16 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 29377711 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EF3268 186 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 29375551 Common rplU 50S ribosomal protein L21 EF0968 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 29377351 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III EF2885 211 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 29375223 Pathogen - hypothetical protein EF0619 1 None None None 29374852 Common rplD 50S ribosomal protein L4 EF0207 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 29377708 Common folP dihydropteroate synthase EF3265 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 29374890 Pathogen - hypothetical protein EF0248 1 None None None 29375476 Common - aspartate aminotransferase EF0891 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 29377266 Common - hypothetical protein EF2794 7 None None None 29376019 Common - adenine methyltransferase, putative EF1452 90 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 29376232 Common - signal peptidase I EF1678 189 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 29377037 Common - hypothetical protein EF2548 10 None None None 29375844 Common rbfA ribosome-binding factor A EF1275 169 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 29374714 Common - ABC transporter, ATP-binding protein EF0056 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 29376145 Common - N-acetylmuramoyl-L-alanine amidase, family 4 EF1583 67 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 29376686 Pathogen - hypothetical protein EF2178 1 None None None 29375268 Common - polysaccharide biosynthesis family protein EF0669 37 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 29375028 Pathogen - hypothetical protein EF0392 1 None None None 29376298 Common hprK HPr kinase/phosphorylase EF1749 64 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 29377595 Common - D-isomer specific 2-hydroxyacid dehydrogenase family protein EF3141 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 29375236 Common - amino acid permease family protein EF0635 145 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 29376758 Common - hypothetical protein EF2253 8 None None None 29375127 Common ssb-2 single-strand binding protein EF0499 212 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 29376756 Pathogen - hypothetical protein EF2251 1 None None None 29375614 Common - lipoprotein, putative EF1035 4 None None None 29375408 Common - hypothetical protein EF0819 4 None None None 29376028 Common - hypothetical protein EF1461 19 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 29375355 Common uvrB excinuclease ABC subunit B EF0762 233 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 29375346 Common - hypothetical protein EF0753 7 None None None 29377285 Common - conserved hypothetical protein TIGR01725 EF2816 3 None None None 29377402 Pathogen - hypothetical protein EF2938 1 None None None 29376368 Pathogen - hypothetical protein EF1825 1 None None None 29377744 Common - hypothetical protein EF3303 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 29376229 Common - ABC transporter, ATP-binding protein EF1675 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 29376042 Common - hypothetical protein EF1475 4 None None None 29375103 Common nrdI ribonucleotide reductase stimulatory protein EF0472 38 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 29376495 Common - D-tyrosyl-tRNA deacylase EF1973 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 29377763 Common citC citrate lyase ligase EF3322 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 29374680 Common - PTS system, mannose-specific IIC component EF0021 35 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29374899 Common - polysaccharide biosynthesis family protein EF0258 27 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 29376930 Common murQ N-acetylmuramic acid-6-phosphate etherase EF2436 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 29375061 Common - TRAP dicarboxylate transporter, DctP subunit EF0429 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 29376012 Pathogen - replicase domain protein EF1445 1 None None None 29377725 Common clpC ATP-dependent Clp protease, ATP-binding subunit ClpC EF3282 242 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 29375270 Common - hypothetical protein EF0672 2 None None None 29377528 Common rpsD 30S ribosomal protein S4 EF3070 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 29376824 Common - hypothetical protein EF2322 2 None None None 29374882 Common - ABC transporter, ATP-binding protein EF0238 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 29376289 Common tryS-2 tyrosyl-tRNA synthetase EF1739 217 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29377047 Common gltA putative oxidoreductase EF2560 225 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 29376690 Common - ABC transporter, ATP-binding protein EF2182 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 29374841 Common gpm phosphoglycerate mutase 1 EF0195 154 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 29375176 Pathogen - hypothetical protein EF0562 1 None None None 29377290 Common - prohead protease EF2821 33 COG3740 COG3740, Phage head maturation protease General function prediction only 29375632 Common - ABC transporter, ATP-binding protein EF1053 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 29376611 Pathogen - hypothetical protein EF2102 1 None None None 29377327 Common - 4-oxalocrotonate tautomerase EF2859 25 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 29375735 Common - PTS system, cellobiose-specific IIB component EF1159 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 29375486 Common - phosphomevalonate kinase EF0902 27 COG1577 ERG12, Mevalonate kinase Lipid metabolism 29376840 Pathogen - hypothetical protein EF2339 1 None None None 29375339 Common - glyoxalase family protein EF0745 7 None None None 29375615 Common - nucleoside diphosphate kinase EF1036 229 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 29377731 Common - DNA-binding response regulator EF3289 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376703 Common - glycosyl transferase, group 2 family protein EF2195 138 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29376802 Common vanRB DNA-binding response regulator VanRB EF2299 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29377379 Common - conserved hypothetical protein TIGR00247 EF2915 186 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 29375364 Common clpP ATP-dependent Clp protease proteolytic subunit EF0771 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 29374869 Common rpmD ribosomal protein L30 EF0225 104 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 29374981 Common - hypothetical protein EF0342 2 None None None 29375838 Common - cell wall surface anchor family protein EF1269 12 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29377005 Pathogen - hypothetical protein EF2516 2 COG5644 COG5644, Uncharacterized conserved protein Function unknown 29374805 Pathogen - hypothetical protein EF0155 1 None None None 29374685 Common - phosphosugar-binding transcriptional regulator, putative EF0027 89 COG1737 RpiR, Transcriptional regulators Transcription 29377275 Common - hypothetical protein EF2804 3 None None None 29377302 Pathogen - hypothetical protein EF2834 1 None None None 29375987 Pathogen - hypothetical protein EF1420 1 None None None 29377179 Pathogen - hypothetical protein EF2699 1 None None None 29377078 Common - glyoxalase family protein EF2591 13 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 29375878 Common dnaJ dnaJ protein EF1310 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 29375848 Common - DNA replication protein, putative EF1279 9 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 29374993 Common - holin, putative EF0354 2 None None None 29375101 Common nrdF ribonucleotide-diphosphate reductase subunit beta EF0470 113 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 29376964 Common argS arginyl-tRNA synthetase EF2471 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375581 Common - hypothetical protein EF0999 53 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 29376480 Pathogen - hypothetical protein EF1956 1 None None None 29376049 Pathogen - hypothetical protein EF1482 1 None None None 29375243 Pathogen - hypothetical protein EF0642 1 None None None 29376989 Common - ABC transporter, permease protein EF2497 115 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 29376102 Common scpA segregation and condensation protein A EF1538 144 COG1354 COG1354, Uncharacterized conserved protein Function unknown 29376201 Common hslV ATP-dependent protease peptidase subunit EF1647 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 29376600 Pathogen - hypothetical protein EF2091 1 None None None 29376040 Common - hypothetical protein EF1473 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 29375693 Common - amino acid ABC transporter, permease protein EF1117 186 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 29375423 Pathogen - hypothetical protein EF0835 1 None None None 29374883 Common - cobalt transport family protein EF0239 98 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 29377224 Common - D-alanine--D-alanyl carrier protein ligase EF2749 215 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 29377494 Common - universal stress protein family EF3035 117 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 29377409 Pathogen - hypothetical protein EF2945 1 None None None 29376315 Common - ABC transporter, ATP-binding protein EF1768 40 COG3910 COG3910, Predicted ATPase General function prediction only 29376067 Common - V-type ATP synthase subunit D EF1500 44 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 29375779 Common - hypothetical protein EF1204 14 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 29375019 Common - hypothetical protein EF0382 18 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 29376607 Pathogen - hypothetical protein EF2098 1 None None None 29376651 Common - transcriptional regulator, Cro/CI family EF2142 20 COG1476 COG1476, Predicted transcriptional regulators Transcription 29376766 Common - hypothetical protein EF2262 4 None None None 29376945 Common coaD pantetheine-phosphate adenylyltransferase EF2451 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 29375447 Common - cation efflux family protein EF0859 219 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 29374749 Common sdhB-1 L-serine dehydratase, iron-sulfur-dependent, beta subunit EF0098 24 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 29375289 Common - phosphosugar-binding transcriptional regulator, RpiR family, putative EF0692 49 COG1737 RpiR, Transcriptional regulators Transcription 29375584 Common divIVA cell division protein DivIVA EF1002 50 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 29375772 Common - metallo-beta-lactamase YycJ EF1197 61 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 29375511 Common - sensor histidine kinase EF0927 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 29375782 Common - sensory box histidine kinase EF1209 41 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 29375108 Pathogen - hypothetical protein EF0478 1 None None None 29375460 Common - copper-translocating P-type ATPase EF0875 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 29377449 Common - ABC transporter, ATP-binding protein EF2986 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29376592 Pathogen - hypothetical protein EF2083 1 None None None 29377426 Common - sugar-binding transcriptional regulator, LacI family EF2962 130 COG1609 PurR, Transcriptional regulators Transcription 29374910 Common - PTS system, beta-glucoside-specific IIABC component EF0270 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29377294 Common - hypothetical protein EF2825 8 COG1403 McrA, Restriction endonuclease Defense mechanisms 29376586 Common - ABC transporter, ATP-binding protein EF2077 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 29376982 Common - hypothetical protein EF2490 4 None None None 29376497 Common - conserved hypothetical protein TIGR00046 EF1975 196 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 29376374 Pathogen - hypothetical protein EF1833 1 None None None 29376864 Common - hypothetical protein EF2366 8 None None None 29376379 Common - PTS system, IIC component EF1838 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 29377164 Common - hypothetical protein EF2683 7 None None None 29375921 Common pdhB pyruvate dehydrogenase complex, E1 component, beta subunit EF1354 220 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 29375186 Pathogen - hypothetical protein EF0574 1 None None None 29375395 Common - amino acid ABC transporter, permease protein EF0806 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 29376599 Common - hypothetical protein EF2090 34 None None None 29377066 Common - diaminopropionate ammonia-lyase EF2579 163 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 29377054 Common selD selenide, water dikinase EF2567 101 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 29376455 Common - alpha-glycerophosphate oxidase EF1928 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 29374900 Common - S4 RNA-binding domain protein EF0259 67 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 29375937 Common - drug resistance transporter, EmrB/QacA family protein EF1370 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29375163 Common - hypothetical protein EF0545 2 None None None 29375719 Common - HD domain protein EF1143 88 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 29376174 Common parE DNA topoisomerase IV subunit B EF1615 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 29374678 Common - PTS system, IIB component EF0019 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29377032 Pathogen - transcriptional regulator, putative EF2543 2 None None None 29377196 Common rplA 50S ribosomal protein L1 EF2718 244 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 29375132 Pathogen - hypothetical protein EF0504 1 None None None 29374923 Common fabZ-1 (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase EF0284 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 29377072 Common - mur ligase family protein EF2585 63 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 29376077 Common - hypothetical protein EF1510 149 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 29376062 Common - V-type ATPase, subunit E EF1495 3 None None None 29377663 Common - IS256, transposase EF3215 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29375734 Common - N4-(beta-N-acetylglucosaminyl)-L-asparaginase, putative EF1158 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 29377629 Common - hypothetical protein EF3179 9 None None None 29375073 Pathogen - hypothetical protein EF0441 1 None None None 29377463 Common - transcriptional regulator, MarR family EF3002 83 COG1846 MarR, Transcriptional regulators Transcription 29374849 Common cfa cyclopropane-fatty-acyl-phospholipid synthase EF0203 128 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 29374704 Common - hypothetical protein EF0046 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 29375988 Common - hypothetical protein EF1421 7 None None None 29376880 Common - hypothetical protein EF2383 28 COG2364 COG2364, Predicted membrane protein Function unknown 29377100 Pathogen - hypothetical protein EF2615 1 None None None 29377192 Pathogen - hypothetical protein EF2712 1 None None None 29376394 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase EF1860 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 29377107 Common - hypothetical protein EF2622 19 COG3592 COG3592, Uncharacterized conserved protein Function unknown 29375712 Pathogen - hypothetical protein EF1136 1 None None None 29375204 Common - ISEf1, transposase EF0595 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29377118 Common groEL chaperonin, 60 kDa EF2633 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 29375658 Pathogen - hypothetical protein EF1081 1 None None None 29377511 Common - hypothetical protein EF3053 13 COG3859 COG3859, Predicted membrane protein Function unknown 29377572 Common rpmB 50S ribosomal protein L28 EF3116 98 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 29376158 Common katA catalase/peroxidase EF1597 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 29374940 Common - transcriptional regulator, GntR family EF0301 121 COG1725 COG1725, Predicted transcriptional regulators Transcription 29375641 Common - deaminase EF1062 63 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 29377527 Common - formate/nitrite transporter family protein EF3069 56 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 29377098 Common atpE ATP synthase F0, C subunit EF2613 24 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 29374952 Pathogen - hypothetical protein EF0313 1 None None None 29375678 Common - conserved hypothetical protein TIGR01655 EF1102 5 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 29375453 Common - glycine betaine/carnitine/choline transporter, ATP-binding protein EF0865 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 29375523 Common mgsA methylglyoxal synthase EF0939 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 29377366 Common - 2',3'-cyclic-nucleotide 2'-phosphodiesterase, putative EF2902 137 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 29376745 Common - sugar-binding transcriptional regulator, LacI family EF2238 121 COG1609 PurR, Transcriptional regulators Transcription 29376913 Common - hypothetical protein EF2419 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 29375855 Common - hypothetical protein EF1286 6 None None None 29375599 Common - PTS system, IIC component EF1019 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29377637 Pathogen - cell wall surface anchor family protein EF3187 1 None None None 29375929 Common - hypothetical protein EF1362 2 None None None 29376162 Common - glycosyl hydrolase, family 13 EF1602 165 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 29375824 Common - hypothetical protein EF1253 57 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 29376547 Common - hypothetical protein EF2036 2 COG3422 COG3422, Uncharacterized conserved protein Function unknown 29374780 Common - transcriptional regulator, Cro/CI family EF0129 15 None None None 29375089 Common - phosphosugar-binding transcriptional regulator, putative EF0458 94 COG1737 RpiR, Transcriptional regulators Transcription 29374774 Common - hypothetical protein EF0123 9 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 29375035 Common - hypothetical protein EF0399 28 COG3819 COG3819, Predicted membrane protein Function unknown 29377080 Common - ABC transporter, ATP-binding/permease protein EF2593 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375384 Common - hypothetical protein EF0794 30 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 29375992 Pathogen - hypothetical protein EF1425 1 None None None 29375652 Pathogen - hypothetical protein EF1074 1 None None None 29375022 Common - major facilitator family transporter EF0385 200 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 29377252 Common - conserved hypothetical protein TIGR00103 EF2780 67 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 29375433 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase EF0845 210 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 29376194 Common - iron compound ABC transporter, ATP-binding protein EF1639 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 29375396 Common - pheromone binding protein, putative EF0807 171 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29376560 Common - ABC transporter, permease protein, putative EF2049 21 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 29374792 Pathogen - hypothetical protein EF0141 1 None None None 29376534 Pathogen - hypothetical protein EF2019 1 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 29377238 Common tmk thymidylate kinase EF2764 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 29375152 Common - IS256, transposase EF0529 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29374664 Common - hypothetical protein EF0003 34 COG2501 COG2501, Uncharacterized conserved protein Function unknown 29376272 Common - uracil permease EF1720 120 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 29376658 Pathogen - hypothetical protein EF2149 1 None None None 29377648 Common - ABC transporter, ATP-binding protein EF3200 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 29375154 Pathogen - hypothetical protein EF0531 1 None None None 29375324 Common - RNA methyltransferase, TrmA family EF0728 203 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 29376343 Common - hypothetical protein EF1798 163 COG0628 PerM, Predicted permease General function prediction only 29375067 Common rhaD rhamnulose-1-phosphate aldolase EF0435 27 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 29375659 Pathogen - hypothetical protein EF1082 1 None None None 29376055 Pathogen - hypothetical protein EF1488 1 None None None 29377042 Common prfA peptide chain release factor 1 EF2554 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 29375114 Pathogen - hypothetical protein EF0486 1 None None None 29376185 Common eutL ethanolamine utilization protein EutL EF1626 16 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 29377651 Common rpmG 50S ribosomal protein L33 EF3203 52 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 29377630 Common - RNA polymerase sigma-70 factor, ECF subfamily EF3180 145 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29376504 Common - universal stress protein family EF1982 137 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 29374767 Common - hypothetical protein EF0116 14 COG4815 COG4815, Uncharacterized protein conserved in bacteria Function unknown 29377270 Pathogen - hypothetical protein EF2798 2 None None None 29376439 Common - hypothetical protein EF1911 6 COG4129 COG4129, Predicted membrane protein Function unknown 29377299 Pathogen - hypothetical protein EF2831 1 None None None 29375458 Common - potassium uptake protein EF0872 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 29376089 Common - hypothetical protein EF1524 43 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 29377502 Common nagA-2 N-acetylglucosamine-6-phosphate deacetylase EF3044 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 29376699 Common - dTDP-4-dehydrorhamnose reductase EF2191 185 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 29377091 Common - hypothetical protein EF2606 8 COG4836 COG4836, Predicted membrane protein Function unknown 29374757 Common arcC-1 carbamate kinase EF0106 73 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 29377133 Common - spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein EF2649 134 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 29375029 Pathogen - hypothetical protein EF0393 1 None None None 29377641 Common - isochorismatase family protein EF3192 110 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 29376211 Common - hypothetical protein EF1657 15 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 29376795 Common - hypothetical protein EF2292 3 None None None 29376182 Common - microcompartment protein EF1623 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 29375625 Common pyk pyruvate kinase EF1046 234 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 29376629 Pathogen - hypothetical protein EF2120 2 None None None 29376004 Pathogen - hypothetical protein EF1437 1 None None None 29377537 Common pepT-2 peptidase T EF3080 58 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 29375761 Common - Ser/Thr protein phosphatase family protein EF1186 98 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 29377025 Pathogen - hypothetical protein EF2536 1 None None None 29375926 Common - hypothetical protein EF1359 41 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 29376835 Common - hypothetical protein EF2334 9 None None None 29377519 Common mreD rod shape-determining protein MreD EF3061 11 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 29377260 Common glcK glucokinase EF2788 156 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 29375058 Common kduI-1 5-keto-4-deoxyuronate isomerase EF0425 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 29376874 Common - amino acid permease family protein EF2377 40 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 29376277 Common - cold-shock domain family protein EF1726 172 COG1278 CspC, Cold shock proteins Transcription 29375609 Common - endonuclease/exonuclease/phosphatase family protein EF1030 10 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 29377660 Common - PTS system, IIC component EF3212 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29375639 Common - pheromone binding protein EF1060 186 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29376923 Common guaC guanosine 5'-monophosphate oxidoreductase EF2429 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 29375594 Common - hypothetical protein EF1014 4 None None None 29376096 Pathogen - hypothetical protein EF1532 1 None None None 29375748 Common - teichoic acid biosynthesis protein B, putative EF1172 19 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 29377718 Common - hydantoinase/oxoprolinase EF3275 115 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29374975 Pathogen - hypothetical protein EF0336 1 None None None 29376393 Common panC pantoate--beta-alanine ligase EF1859 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 29376622 Pathogen - hypothetical protein EF2113 2 None None None 29374785 Pathogen - hypothetical protein EF0134 1 None None None 29376082 Common - PTS system, IIABC components EF1516 59 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29374730 Common - hypothetical protein EF0077 5 None None None 29375778 Common - Holliday junction resolvase-like protein EF1203 152 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 29377147 Common - phosphoglycerate mutase family protein EF2664 124 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 29375191 Common - transcriptional regulator, putative EF0579 7 COG1309 AcrR, Transcriptional regulator Transcription 29376398 Common - permease, putative EF1867 15 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 29376136 Pathogen - hypothetical protein EF1573 1 None None None 29375899 Common - hypothetical protein EF1332 4 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 29375832 Pathogen - hypothetical protein EF1263 1 None None None 29375119 Common - hypothetical protein EF0491 9 COG3942 COG3942, Surface antigen General function prediction only 29376308 Common - phosphate ABC transporter, phosphate-binding protein EF1759 173 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 29375704 Common sgaB phosphotransferase enzyme II, B compnent SgaB EF1128 8 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 29376409 Pathogen - hypothetical protein EF1880 2 None None None 29374906 Common ftsH cell division protein FtsH EF0265 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 29375941 Common phnA phnA protein EF1374 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 29376463 Common - hypothetical protein EF1937 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 29376664 Common - hypothetical protein EF2156 17 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 29377624 Common - hypothetical protein EF3174 56 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 29376301 Common - hypothetical protein EF1752 25 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 29377034 Common - hypothetical protein EF2545 9 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 29375277 Common - penicillin-binding protein 2A EF0680 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 29376223 Common - glyoxylase family protein EF1669 36 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 29375816 Common - glycosyl hydrolase, family 1 EF1243 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 29377296 Common - transcriptional regulator, ArpU family EF2828 2 None None None 29375272 Common - glycine betaine/carnitine/choline ABC transporter, ATP-binding protein EF0674 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 29376150 Common - acetyltransferase, GNAT family EF1589 8 COG0456 RimI, Acetyltransferases General function prediction only 29376442 Pathogen - hypothetical protein EF1914 1 None None None 29377765 Common - sodium ion-translocating decarboxylase, beta subunit EF3324 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 29375997 Common - hypothetical protein EF1430 52 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 29376250 Common - NADPH-dependent FMN reductase domain protein EF1698 98 COG0431 COG0431, Predicted flavoprotein General function prediction only 29376483 Common eno enolase EF1961 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 29376958 Common - hypothetical protein EF2464 41 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29375576 Common murG N-acetylglucosaminyl transferase EF0994 210 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 29375303 Common clpE ATP-dependent Clp protease, ATP-binding subunit ClpE EF0706 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 29374897 Common pth peptidyl-tRNA hydrolase EF0256 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 29377543 Common - hypothetical protein EF3086 10 COG5506 COG5506, Uncharacterized conserved protein Function unknown 29376119 Common - hypothetical protein EF1556 26 COG1694 MazG, Predicted pyrophosphatase General function prediction only 29375561 Common xseA exodeoxyribonuclease VII large subunit EF0979 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 29377753 Common trmE tRNA modification GTPase TrmE EF3312 226 COG0486 ThdF, Predicted GTPase General function prediction only 29374719 Common - pheromone binding protein, putative EF0063 191 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29374866 Common rplF 50S ribosomal protein L6 EF0221 245 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 29375314 Common fruK-2 1-phosphofructokinase EF0718 96 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 29375864 Common - acetyltransferase, GNAT family EF1296 68 COG3153 COG3153, Predicted acetyltransferase General function prediction only 29375438 Common - transcriptional regulator, PemK family EF0850 54 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 29374938 Common copZ copper transport protein CopZ EF0299 12 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 29375886 Pathogen - hypothetical protein EF1318 1 None None None 29375317 Common pcrA ATP-dependent DNA helicase PcrA EF0721 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 29375682 Pathogen - hypothetical protein EF1106 1 None None None 29376631 Pathogen - hypothetical protein EF2122 1 None None None 29376490 Common - hypothetical protein EF1968 15 COG4720 COG4720, Predicted membrane protein Function unknown 29374695 Common proA gamma-glutamyl phosphate reductase EF0037 190 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 29376569 Common cydB cytochrome d ubiquinol oxidase, subunit II EF2060 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 29376234 Common - hypothetical protein EF1680 12 COG4479 COG4479, Uncharacterized protein conserved in bacteria Function unknown 29376878 Pathogen - hypothetical protein EF2381 1 None None None 29376349 Common - glycosyl hydrolase, family 35 EF1805 25 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 29376401 Common - thioredoxin family protein EF1871 51 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 29375580 Common - conserved hypothetical protein TIGR00044 EF0998 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 29374797 Common - surface exclusion protein, putative EF0146 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 29374711 Common dnaQ DNA polymerase III, epsilon subunit EF0053 130 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 29377428 Common ulaA ascorbate-specific PTS system enzyme IIC EF2964 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 29377203 Common - pheromone binding protein EF2725 194 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29374738 Common - hypothetical protein EF0085 5 COG3711 BglG, Transcriptional antiterminator Transcription 29376389 Common - glycosyl hydrolase, family 35 EF1851 26 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 29376517 Common - minor structural protein EF2001 6 COG4926 PblB, Phage-related protein Function unknown 29377301 Common - hypothetical protein EF2833 7 None None None 29376580 Common - hypothetical protein EF2071 7 None None None 29377001 Pathogen - lipoprotein, putative EF2512 1 None None None 29375374 Common - acyltransferase, putative EF0783 97 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 29377484 Pathogen - hypothetical protein EF3024 1 None None None 29374896 Common ldh L-lactate dehydrogenase EF0255 174 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 29375912 Common - sugar ABC transporter, sugar-binding protein EF1345 74 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 29375811 Common - glycosyl hydrolase, family 3 EF1238 136 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 29377382 Common - bacterial transferase, putative EF2918 209 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 29375241 Pathogen - hypothetical protein EF0640 1 None None None 29376798 Common - D-specific alpha-keto acid dehydrogenase EF2295 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 29375335 Common - hypothetical protein EF0741 4 None None None 29376058 Common - hypothetical protein EF1491 33 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 29375053 Common - drug resistance transporter, EmrB/QacA family protein EF0420 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29375125 Pathogen - hypothetical protein EF0497 1 None None None 29376472 Pathogen - hypothetical protein EF1947 1 None None None 29376070 Common - fructose-1,6-bisphosphatase, putative EF1503 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 29376966 Common - ribosomal-protein-alanine acetyltransferase, putative EF2473 175 COG0456 RimI, Acetyltransferases General function prediction only 29377418 Common - transcriptional regulator, Cro/CI family EF2954 17 COG1395 COG1395, Predicted transcriptional regulator Transcription 29377539 Common - iron compound ABC transporter, substrate-binding protein EF3082 94 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 29375918 Pathogen - hypothetical protein EF1351 1 None None None 29376754 Pathogen - hypothetical protein EF2249 1 None None None 29374850 Common rpsJ 30S ribosomal protein S10 EF0205 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 29377693 Pathogen - hypothetical protein EF3250 1 None None None 29376203 Common gid tRNA (uracil-5-)-methyltransferase Gid EF1649 194 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 29376296 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase EF1747 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 29376527 Pathogen - hypothetical protein EF2012 1 None None None 29374682 Common - hypothetical protein EF0024 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 29375221 Common - hypothetical protein EF0617 11 COG0730 COG0730, Predicted permeases General function prediction only 29377593 Common - PTS system, IIC component EF3139 27 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29375449 Common - acetyltransferase, GNAT family EF0861 12 None None None 29375842 Common - ribosomal protein L7A family EF1273 27 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 29376684 Common - glycosyl transferase, group 2 family protein EF2176 163 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29374690 Common - hypothetical protein EF0032 11 COG4485 COG4485, Predicted membrane protein Function unknown 29375234 Common tryS-1 tyrosyl-tRNA synthetase EF0633 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375956 Common - NAD-dependent formate dehydrogenase, beta subunit, putative EF1389 162 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 29376038 Common - hypothetical protein EF1471 3 None None None 29376641 Common - recT protein, putative EF2132 15 COG3723 RecT, Recombinational DNA repair protein (RecE pathway) DNA replication, recombination, and repair 29375348 Common - hypothetical protein EF0755 8 None None None 29376736 Common - hypothetical protein EF2229 14 None None None 29377635 Common - hypothetical protein EF3185 7 None None None 29377400 Pathogen - hypothetical protein EF2936 1 None None None 29377391 Common - hydrolase, haloacid dehalogenase-like family EF2927 184 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 29377682 Common rpoB DNA-directed RNA polymerase subunit beta EF3238 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 29375965 Common - molybdenum ABC transporter, permease protein EF1398 200 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 29376033 Common - hypothetical protein EF1466 7 None None None 29374931 Common - PTS system, IIC component EF0292 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29376935 Common - hypothetical protein EF2441 69 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 29377702 Common - hypothetical protein EF3259 12 COG4769 COG4769, Predicted membrane protein Function unknown 29376990 Common - ABC transporter, ATP-binding protein EF2498 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 29377565 Common - peptide ABC transporter, ATP-binding protein EF3109 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 29376720 Common - PTS system, IIBC components EF2213 43 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29376079 Common - hypothetical protein EF1512 27 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 29375366 Common - hypothetical protein EF0774 27 COG4828 COG4828, Predicted membrane protein Function unknown 29375853 Common - structural protein, putative EF1284 3 None None None 29376121 Common papS poly A polymerase EF1558 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 29377039 Common glyA serine hydroxymethyltransferase EF2550 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 29377287 Pathogen - minor structural protein, putative EF2818 2 None None None 29376418 Common - hypothetical protein EF1889 5 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 29375353 Common - amino acid ABC transporter, ATP-binding protein EF0760 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 29377434 Common - hypothetical protein EF2970 4 None None None 29375104 Common nrdH ribonucleoside-diphosphate reductase 2, NrdH-redoxin EF0473 38 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 29374847 Common tuf elongation factor Tu EF0201 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 29375608 Common - hypothetical protein EF1029 4 None None None 29377332 Pathogen - hypothetical protein EF2864 2 None None None 29377734 Common guaB inositol-5-monophosphate dehydrogenase EF3293 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 29377683 Common - hypothetical protein EF3239 13 COG3478 COG3478, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 29376475 Common - mocD family protein, putative EF1950 19 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 29376575 Common - transcriptional regulator, TetR family EF2066 30 COG1309 AcrR, Transcriptional regulator Transcription 29377478 Common - hypothetical protein EF3018 7 None None None 29377689 Common - cell-envelope associated acid phosphatase EF3245 67 COG1316 LytR, Transcriptional regulator Transcription 29374826 Common - basic membrane protein family EF0176 100 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 29374986 Pathogen - peptide methionine sulfoxide reductase domain protein EF0347 1 None None None 29375388 Common - hypothetical protein EF0798 6 COG4709 COG4709, Predicted membrane protein Function unknown 29375095 Common dapF diaminopimelate epimerase EF0464 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 29375213 Pathogen - hypothetical protein EF0608 1 None None None 29375969 Common - hypothetical protein EF1402 10 None None None 29377314 Common - hypothetical protein EF2846 2 None None None 29375195 Common - ABC transporter, ATP-binding protein/permease protein EF0583 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29376410 Common - hypothetical protein EF1881 5 None None None 29376997 Common - cell wall surface anchor family protein EF2505 8 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29375087 Common - PTS system, IID component EF0456 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29376266 Common pyrD-2 dihydroorotate dehydrogenase EF1714 237 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 29376128 Common - prephenate dehydrogenase EF1565 150 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 29374809 Pathogen - hypothetical protein EF0159 2 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 29375341 Common - hypothetical protein EF0747 42 COG4420 COG4420, Predicted membrane protein Function unknown 29376356 Pathogen - hypothetical protein EF1812 1 None None None 29377679 Common - gluconate kinase, putative EF3235 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 29374828 Common - ABC transporter, ATP-binding protein EF0178 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 29375261 Common - hypothetical protein EF0662 9 COG5652 COG5652, Predicted integral membrane protein Function unknown 29377672 Pathogen - hypothetical protein EF3225 1 None None None 29375478 Common - amino acid ABC transporter, amino acid-binding/permease protein EF0893 187 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 29375826 Common - ABC transporter, ATP-binding protein EF1255 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 29374802 Pathogen - hypothetical protein EF0152 1 None None None 29377342 Common accD acetyl-CoA carboxylase subunit beta EF2876 220 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 29376134 Pathogen - hypothetical protein EF1571 1 None None None 29376773 Common - PTS system, IID component EF2269 39 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29377617 Common hexA DNA mismatch repair protein EF3167 203 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 29376951 Common - cell division protein, FtsW/RodA/SpoVE family EF2457 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 29374815 Common - hypothetical protein EF0165 6 None None None 29376169 Common - hypothetical protein EF1610 3 None None None 29377109 Pathogen - hypothetical protein EF2624 1 None None None 29374676 Common - ABC transporter, ATP-binding protein EF0017 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 29374912 Common - glycosyl hydrolase, family 1 EF0272 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 29375491 Common - peptide ABC transporter, peptide-binding protein EF0907 191 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29376716 Pathogen - hypothetical protein EF2209 1 None None None 29377110 Common nadE NAD synthetase EF2625 119 COG0171 NadE, NAD synthase Coenzyme metabolism 29374909 Common lysS lysyl-tRNA synthetase EF0268 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 29377040 Common - Sua5/YciO/YrdC/YwlC family protein EF2552 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 29377476 Common - sodium:dicarboxylate symporter family protein EF3015 89 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 29375821 Common - fibronectin/fibrinogen-binding protein, putative EF1249 80 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 29376980 Pathogen - lipoprotein, putative EF2488 1 None None None 29377454 Common - hypothetical protein EF2991 113 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 29377396 Common - AhpC/TSA family protein EF2932 152 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 29375780 Common - malate dehydrogenase, decarboxylating EF1206 202 COG0281 SfcA, Malic enzyme Energy production and conversion 29375044 Common - PTS system, IIA component EF0408 51 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 29375239 Common - hypothetical protein EF0638 8 COG4808 COG4808, Uncharacterized protein conserved in bacteria Function unknown 29375902 Common - sensor histidine kinase, putative EF1335 24 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 29374984 Common - hypothetical protein EF0345 2 None None None 29375165 Common - ammonium transporter family protein EF0547 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 29376697 Common - hypothetical protein EF2189 3 COG2456 COG2456, Uncharacterized conserved protein Function unknown 29377421 Common - hexapeptide-repeat containing-acetyltransferase EF2957 195 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 29376025 Pathogen - hypothetical protein EF1458 1 None None None 29375789 Pathogen - hypothetical protein EF1216 1 None None None 29375287 Common - hypothetical protein EF0690 9 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 29375393 Common - amino acid ABC transporter, amino acid-binding protein EF0804 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 29377064 Common - hypothetical protein EF2577 225 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 29376377 Common - PTS system, IIA component, putative EF1836 14 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 29377440 Common - PTS system, IID component EF2977 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29376536 Pathogen - hypothetical protein EF2021 1 None None None 29377525 Common - hydrolase, haloacid dehalogenase-like family EF3067 133 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 29375440 Common - hypothetical protein EF0852 40 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 29376862 Common - xanthine permease EF2364 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 29376940 Common holA DNA polymerase III subunit delta EF2446 71 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 29375071 Pathogen - immunity protein PlnM, putative EF0439 1 None None None 29375884 Common - transcriptional regulator, Cro/CI family EF1316 10 None None None 29375577 Common ftsQ cell division protein FtsQ EF0995 13 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 29376160 Common - TPR domain transcriptional regulator, Cro/CI family EF1599 10 None None None 29376452 Pathogen - hypothetical protein EF1925 1 None None None 29377665 Common - helicase, putative EF3217 159 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 29377184 Common mutY A/G-specific adenine glycosylase EF2704 232 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 29374962 Pathogen - hypothetical protein EF0323 1 None None None 29374707 Common - sigma-70 factor family protien EF0049 33 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29377105 Common secG preprotein translocase, SecG subunit EF2620 12 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 29377619 Common - conserved hypothetical protein TIGR00282 EF3169 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 29375180 Common kdpA potassium-transporting ATPase subunit A EF0567 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 29375714 Common - oxidoreductase, aldo/keto reductase family EF1138 193 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 29376060 Common - V-type ATP synthase subunit I EF1493 48 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 29375596 Common - hypothetical protein EF1016 4 None None None 29377190 Common - amino acid permease family protein EF2710 63 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 29376354 Common gspA-1 general stress protein A EF1810 36 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 29375558 Common - hypothetical protein EF0976 27 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 29376425 Pathogen - hypothetical protein EF1897 1 None None None 29374978 Common - major capsid protein, putative EF0339 2 None None None 29377349 Common fabK enoyl-(acyl-carrier-protein) reductase II EF2883 150 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 29377051 Common - hypothetical protein EF2564 20 None None None 29375342 Common - hypothetical protein EF0748 111 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 29377375 Common - DNA-binding response regulator, LuxR family EF2911 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 29376287 Common - hypothetical protein EF1737 7 None None None 29375333 Common - nicotinamide mononucleotide transporter PnuC, putative EF0739 46 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 29375410 Common - hydrolase, haloacid dehalogenase-like family EF0822 64 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 29376249 Common - acetyltransferase, GNAT family EF1695 11 COG0456 RimI, Acetyltransferases General function prediction only 29375617 Common - lipoprotein, putative EF1038 3 None None None 29376327 Common purM phosphoribosylaminoimidazole synthetase EF1780 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 29375174 Common xylB D-xylulose kinase EF0557 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 29376342 Common - hypothetical protein EF1797 2 None None None 29374880 Common - peptidase, M20/M25/M40 family EF0236 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 29375290 Common fruK-1 1-phosphofructokinase EF0693 97 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 29374671 Common - DHH family protein EF0011 76 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 29375836 Common rnhC ribonuclease HIII EF1267 27 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 29377416 Pathogen - hypothetical protein EF2952 1 None None None 29376242 Common recJ single-stranded-DNA-specific exonuclease RecJ EF1688 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 29375737 Common - hypothetical protein EF1161 8 None None None 29377003 Pathogen - hypothetical protein EF2514 1 None None None 29375514 Common metG methionyl-tRNA synthetase EF0930 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375570 Common - hypothetical protein EF0988 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 29376678 Common - glycosyl transferase, group 2 family protein EF2170 219 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29375634 Common - tunicamycin resistance protein, putative EF1055 13 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 29377495 Common - thioredoxin family protein EF3036 80 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 29374889 Common - amino acid ABC transporter, amino acid-binding/permease protein EF0247 178 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 29377759 Common citX 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase EF3318 24 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 29375010 Common - DNA-binding response regulator EF0372 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376666 Common - pyruvate ferredoxin/flavodoxin oxidoreductase family protein EF2158 119 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 29376804 Pathogen - hypothetical protein EF2302 1 None None None 29375861 Common - holin, putative EF1292 14 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 29377094 Common atpG F0F1 ATP synthase subunit gamma EF2609 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 29374991 Pathogen - hypothetical protein EF0352 1 None None None 29377377 Common - hypothetical protein EF2913 9 COG4758 COG4758, Predicted membrane protein Function unknown 29374740 Common - hypothetical protein EF0089 20 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29375904 Common - hypothetical protein EF1337 2 None None None 29375931 Common - acetyl-CoA acetyltransferase/hydroxymethylglutaryl-CoA reductase, degradative EF1364 188 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 29376313 Common comFC competence protein F EF1765 81 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 29375065 Common - rhamnulokinase, putative EF0433 108 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 29376508 Pathogen - hypothetical protein EF1987 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 29375024 Common - sodium/dicarboxylate symporter family protein EF0387 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 29374747 Common - hypothetical protein EF0096 49 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 29375620 Common - xanthine/uracil permeases family protein EF1041 134 COG2252 COG2252, Permeases General function prediction only 29374933 Common - hypothetical protein EF0294 68 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 29376857 Common - hypothetical protein EF2357 3 COG2259 COG2259, Predicted membrane protein Function unknown 29377492 Common - PTS system, IIA component EF3033 11 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29376786 Common - site-specific recombinase, resolvase family, putative EF2283 96 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 29375123 Pathogen - hypothetical protein EF0495 1 None None None 29375846 Common - transcriptional regulator, Cro/CI family EF1277 8 None None None 29375110 Common - excisionase, putative EF0480 3 None None None 29376503 Pathogen - hypothetical protein EF1981 1 None None None 29377766 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit EF3325 164 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 29374760 Common - ThiJ/PfpI family protein EF0109 86 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 29376609 Pathogen - hypothetical protein EF2100 1 None None None 29375488 Common mvk mevalonate kinase EF0904 54 COG1577 ERG12, Mevalonate kinase Lipid metabolism 29376973 Common - hypothetical protein EF2480 3 None None None 29376069 Common - beta-lactamase, putative EF1502 27 COG2367 PenP, Beta-lactamase class A Defense mechanisms 29375282 Common - rotamase family protein EF0685 85 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 29375549 Common - transcriptional regulator, MerR family EF0966 52 COG0789 SoxR, Predicted transcriptional regulators Transcription 29374871 Common secY preprotein translocase subunit SecY EF0227 238 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 29377028 Pathogen - hypothetical protein EF2539 1 None None None 29377724 Common - hypothetical protein EF3281 30 COG1289 COG1289, Predicted membrane protein Function unknown 29374967 Common - hypothetical protein EF0328 32 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 29375140 Common - DNA-damage-inducible protein J, putative EF0512 21 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 29377127 Common - hypothetical protein EF2643 14 COG3597 COG3597, Uncharacterized protein/domain associated with GTPases Function unknown 29375866 Common - hypothetical protein EF1298 7 COG4817 COG4817, Uncharacterized protein conserved in bacteria Function unknown 29375031 Common - methionine synthase, putative EF0395 46 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 29376793 Common - RNA polymerase sigma-70 factor, ECF subfamily EF2290 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29375808 Pathogen - hypothetical protein EF1235 1 None None None 29377579 Common fmt methionyl-tRNA formyltransferase EF3123 223 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 29376180 Common - hypothetical protein EF1621 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 29377729 Common - phosphosugar-binding transcriptional regulator, putative EF3286 94 COG1737 RpiR, Transcriptional regulators Transcription 29374958 Common - hypothetical protein EF0319 15 None None None 29377150 Common - copper homeostasis protein, putative EF2667 58 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 29376918 Common - pyrroline-5-carboxylate reductase, putative EF2424 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 29376183 Common - aldehyde dehydrogenase, putative EF1624 183 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 29374769 Common - ornithine cyclodeaminase, putative EF0118 101 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 29374955 Pathogen - hypothetical protein EF0316 1 None None None 29377304 Common - hypothetical protein EF2836 5 None None None 29376554 Common - site-specific recombinase, phage integrase family EF2043 146 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29376627 Common - hypothetical protein EF2118 11 None None None 29375949 Common pepT-1 peptidase T EF1382 59 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 29377716 Common - hypothetical protein EF3273 2 None None None 29376648 Pathogen - hypothetical protein EF2139 1 None None None 29376117 Common - hypothetical protein EF1554 5 COG5582 COG5582, Uncharacterized conserved protein Function unknown 29374977 Common - scaffold protein EF0338 6 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375627 Common rpmF-3 50S ribosomal protein L32 EF1048 30 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 29376143 Common - hypothetical protein EF1580 15 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 29377262 Common - small hydrophobic molecule transporter protein, putative EF2790 153 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 29377588 Common eda-2 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase EF3134 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 29376921 Common - hypothetical protein EF2427 7 None None None 29375056 Common eda-1 keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase EF0423 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 29376294 Common - hypothetical protein EF1745 7 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 29376873 Pathogen - hypothetical protein EF2376 1 None None None 29374687 Common - aminotransferase, class II EF0029 225 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 29375741 Common - nucleotide-binding protein EF1165 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 29375621 Common - multidrug resistance protein, putative EF1042 181 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29376098 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type EF1534 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 29375082 Common - putative 6-phosphogluconolactonase EF0451 98 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 29376006 Pathogen - hypothetical protein EF1439 1 None None None 29376361 Common - serine proteinase, V8 family EF1817 20 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 29374759 Common - C4-dicarboxylate transporter, putative EF0108 42 COG1288 COG1288, Predicted membrane protein Function unknown 29374777 Pathogen - hypothetical protein EF0126 1 None None None 29377194 Common rplL ribosomal protein L7/L12 EF2715 210 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 29377658 Common - PTS system, IIA component, putative EF3210 7 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29375521 Common - hypothetical protein EF0937 7 None None None 29374750 Common sdhA-1 L-serine dehydratase, iron-sulfur-dependent, alpha subunit EF0099 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 29377364 Pathogen - hypothetical protein EF2900 1 None None None 29376620 Pathogen - hypothetical protein EF2111 1 None None None 29377576 Common - serine/threonine protein kinase EF3120 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 29377505 Common - hypothetical protein EF3047 14 None None None 29376743 Common - hypothetical protein EF2236 19 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 29377548 Common - YitT family protein EF3091 80 COG1284 COG1284, Uncharacterized conserved protein Function unknown 29376156 Common - MutT/nudix family protein EF1595 31 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 29377115 Common - transcriptional regulator EF2630 149 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29377259 Common - rhodanese family protein EF2787 96 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 29375534 Common - conserved hypothetical protein TIGR00150 EF0950 205 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 29376208 Common - GTPase of unknown function EF1654 130 COG1161 COG1161, Predicted GTPases General function prediction only 29375656 Common - multidrug resistance protein, putative EF1078 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29377570 Common - DAK2 domain protein EF3114 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 29377014 Pathogen - cell wall surface anchor family protein EF2525 4 None None None 29375676 Common - ABC transporter, ATP-binding/permease protein EF1100 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375691 Common pheS phenylalanyl-tRNA synthetase subunit alpha EF1115 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 29375871 Common - transcriptional regulator, LysR family EF1303 185 COG0583 LysR, Transcriptional regulator Transcription 29376911 Common rpsU 30S ribosomal protein S21 EF2416 95 None None None 29377166 Pathogen - cell wall surface anchor family protein EF2685 1 None None None 29375130 Common - hypothetical protein EF0502 15 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 29375750 Pathogen - hypothetical protein EF1174 1 None None None 29377233 Common - tetrapyrrole methylase family protein EF2759 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 29375431 Common - D-alanine--D-alanine ligase EF0843 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 29377210 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase EF2733 208 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 29376545 Pathogen - hypothetical protein EF2033 1 None None None 29374700 Common ispF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase EF0042 188 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 29376320 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase EF1773 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29376407 Common - ATP/GTP-binding protein, putative EF1878 15 COG0433 COG0433, Predicted ATPase General function prediction only 29377513 Common - hypothetical protein EF3055 5 None None None 29376270 Common pyrC dihydroorotase EF1718 214 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 29376903 Pathogen - hypothetical protein EF2408 1 None None None 29376257 Common - phosphate-binding protein EF1705 102 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 29377222 Common dltC D-alanine--poly(phosphoribitol) ligase subunit 2 EF2747 12 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29375015 Common - ankyrin repeat family protein EF0377 89 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 29374945 Common - transcriptional regulator, Cro/CI family EF0306 25 COG1395 COG1395, Predicted transcriptional regulator Transcription 29375202 Common - polysaccharide deacetylase family protein EF0590 119 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 29375156 Pathogen - hypothetical protein EF0533 1 None None None 29375322 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B EF0726 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 29374794 Common - transcriptional regulator, Cro/CI family EF0143 8 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 29376656 Pathogen - hypothetical protein EF2147 1 None None None 29376768 Common kduI-2 5-keto-4-deoxyuronate isomerase EF2264 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 29375018 Pathogen - hypothetical protein EF0381 2 COG0657 Aes, Esterase/lipase Lipid metabolism 29376165 Pathogen - hypothetical protein EF1605 1 None None None 29377696 Pathogen - cell wall surface anchor family protein EF3253 1 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29375131 Common - hypothetical protein EF0503 25 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 29377313 Pathogen - hypothetical protein EF2845 1 None None None 29377321 Pathogen - hypothetical protein EF2853 2 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 29375947 Common - hypothetical protein EF1380 30 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 29376486 Common gap-2 glyceraldehyde-3-phosphate dehydrogenase EF1964 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 29376774 Common - PTS system, IIC component EF2270 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29375623 Common dnaE DNA polymerase III, alpha subunit EF1044 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 29377052 Pathogen - hypothetical protein EF2565 1 None None None 29376216 Common buk butyrate kinase EF1662 138 COG3426 COG3426, Butyrate kinase Energy production and conversion 29374979 Pathogen - hypothetical protein EF0340 1 None None None 29376654 Common - site-specific recombinase, phage integrase family EF2145 70 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29376916 Common hom homoserine dehydrogenase EF2422 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 29375200 Common rpmG 50S ribosomal protein L33 EF0588 60 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 29375590 Common - ATP-dependent RNA helicase, DEAD/DEAH box family EF1009 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 29377704 Pathogen - transcriptional regulator, AbrB family EF3261 1 COG2336 MazE, Growth regulator Signal transduction mechanisms 29375689 Common rexA exonuclease RexA EF1113 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 29377404 Pathogen - hypothetical protein EF2940 1 None None None 29375830 Common - sensor histidine kinase EF1261 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 29377456 Common - aminotransferase, class V EF2994 154 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 29375645 Pathogen - hypothetical protein EF1067 1 None None None 29375085 Common - hypothetical protein EF0454 25 COG0730 COG0730, Predicted permeases General function prediction only 29376275 Common - CBS domain protein EF1724 7 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 29375077 Common - O-succinylbenzoic acid--CoA ligase EF0446 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29375823 Pathogen - hypothetical protein EF1251 1 None None None 29377506 Common - hypothetical protein EF3048 51 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 29376673 Common - NAD-dependent epimerase/dehydratase family protein EF2165 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 29377575 Common - conserved hypothetical protein TIGR00157 EF3119 163 COG1162 COG1162, Predicted GTPases General function prediction only 29377007 Pathogen - hypothetical protein EF2518 1 None None None 29375381 Common - transcriptional regulator, TetR family EF0791 137 COG1309 AcrR, Transcriptional regulator Transcription 29377135 Common - spermidine/putrescine ABC transporter, permease protein EF2651 196 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 29376155 Pathogen - hypothetical protein EF1594 1 None None None 29377655 Common - dihydrouridine synthase family protein EF3207 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 29375527 Common - hypothetical protein EF0943 12 COG4905 COG4905, Predicted membrane protein Function unknown 29374949 Pathogen - hypothetical protein EF0310 1 None None None 29377073 Common - cobyric acid synthase, putative EF2586 47 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 29374772 Pathogen - hypothetical protein EF0121 1 None None None 29376553 Common - hypothetical protein EF2042 4 None None None 29375874 Common hrcA heat-inducible transcription repressor EF1306 149 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 29376814 Common topB-2 DNA topoisomerase III EF2312 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 29376064 Common - V-type ATP synthase subunit F EF1497 5 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 29375072 Common - di-/tripeptide transporter EF0440 83 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 29375896 Common - HesA/MoeB/ThiF family protein EF1329 100 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 29375672 Pathogen - hypothetical protein EF1096 1 COG2155 COG2155, Uncharacterized conserved protein Function unknown 29375766 Common - DegV family protein EF1191 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 29377129 Common - hypothetical protein EF2645 36 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 29375054 Common - transcriptional regulator, MerR family EF0421 7 COG0789 SoxR, Predicted transcriptional regulators Transcription 29377243 Common - ABC transporter, ATP-binding protein EF2769 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 29375372 Common - cold shock domain family protein EF0781 181 COG1278 CspC, Cold shock proteins Transcription 29377116 Pathogen - hypothetical protein EF2631 1 None None None 29375328 Common - amino acid permease family protein EF0733 55 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 29375207 Common - transcriptional regulator, TetR family EF0601 23 COG1309 AcrR, Transcriptional regulator Transcription 29375520 Common ksgA dimethyladenosine transferase EF0936 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 29377258 Common - hypothetical protein EF2786 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 29375751 Common gct glycerol-3-phosphate cytidylyltransferase EF1175 106 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 29377524 Common def peptide deformylase EF3066 210 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 29376595 Common - endolysin EF2086 34 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 29375030 Common - secreted antigen, putative EF0394 18 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 29376617 Pathogen - hypothetical protein EF2108 1 None None None 29376499 Common - hypothetical protein EF1977 4 None None None 29375198 Common rpmF 50S ribosomal protein L32 EF0586 78 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 29376321 Common - hypothetical protein EF1774 17 COG4708 COG4708, Predicted membrane protein Function unknown 29375451 Common - glycine betaine/carnitine/choline ABC transporter, glycine betaine/carnitine/choline-binding protein EF0863 88 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 29374763 Pathogen - hypothetical protein EF0112 1 COG1475 Spo0J, Predicted transcriptional regulators Transcription 29376926 Common - metallo-beta-lactamase superfamily protein EF2432 192 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 29377059 Common - molybdenum transport domain protein EF2572 88 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 29377749 Common srlR transcriptional regulator SrlR EF3308 15 COG4578 GutM, Glucitol operon activator Transcription 29376364 Common agrBfs agrBfs protein EF1821 7 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 29376171 Common pflA pyruvate formate-lyase activating enzyme EF1612 104 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 29377514 Common - sortase family protein EF3056 17 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 29377645 Common - sensor histidine kinase EF3197 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 29377740 Common - ATPase, ParA family EF3299 212 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 29377155 Common - hypothetical protein EF2673 9 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 29377124 Common - transcriptional regulator, GntR family EF2640 42 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 29377485 Common - conserved hypothetical protein TIGR00246 EF3025 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 29375429 Common - hypothetical protein EF0841 225 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 29377205 Common - lipoprotein, putative EF2728 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 29375606 Common - hypothetical protein EF1026 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 29377153 Common - hypothetical protein EF2671 71 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 29376198 Common - lacX protein, putative EF1644 43 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 29377234 Common - hypothetical protein EF2760 14 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 29374688 Common - endoribonuclease L-PSP, putative EF0030 179 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 29376791 Pathogen - hypothetical protein EF2288 1 None None None 29375744 Pathogen - hypothetical protein EF1168 1 None None None 29374701 Common gltX glutamyl-tRNA synthetase EF0043 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 29375248 Common - hypothetical protein EF0647 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 29374886 Common - acetyltransferase, GNAT family EF0244 55 COG0456 RimI, Acetyltransferases General function prediction only 29377666 Common - mutator MutT protein, putative EF3218 163 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 29374790 Common - FtsK/SpoIIIE family protein EF0139 17 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 29377687 Pathogen - hypothetical protein EF3243 1 None None None 29375417 Common - hypothetical protein EF0829 11 None None None 29376708 Common map methionine aminopeptidase EF2200 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 29377227 Common - ABC transporter, ATP-binding protein EF2752 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29374893 Common - transcriptional regulator, putative EF0251 15 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 29376056 Common - hypothetical protein EF1489 2 None None None 29374887 Common - decarboxylase family protein EF0245 112 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 29375283 Pathogen - hypothetical protein EF0686 1 COG4980 GvpP, Gas vesicle protein General function prediction only 29375106 Common feoB ferrous iron transport protein B EF0476 162 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 29376014 Pathogen - hypothetical protein EF1447 1 None None None 29376340 Common - hypothetical protein EF1794 10 COG4876 COG4876, Uncharacterized protein conserved in bacteria Function unknown 29376588 Common - peptidase, M20/M25/M40 family EF2079 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 29376544 Pathogen - hypothetical protein EF2032 1 None None None 29377467 Common - hypothetical protein EF3006 6 None None None 29375128 Common - hypothetical protein EF0500 13 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 29374729 Common - oxidoreductase, short chain dehydrogenase/reductase family EF0076 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29376359 Common - transcriptional regulator, LysR family, putative EF1815 149 COG0583 LysR, Transcriptional regulator Transcription 29375487 Common mvaD mevalonate diphosphate decarboxylase EF0903 31 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 29377490 Common - PTS system, IIB component EF3031 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29376245 Common - metallo-beta-lactamase, AtsA/ElaC family EF1691 123 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 29375619 Common - hypothetical protein EF1040 17 COG4330 COG4330, Predicted membrane protein Function unknown 29377180 Common - MutT/nudix family protein EF2700 120 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 29376235 Common msrA peptide methionine sulfoxide reductase EF1681 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 29377602 Common - peptidase, M16 family EF3150 191 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 29376602 Common - endolysin domain protein EF2093 4 None None None 29375493 Common - peptide ABC transporter, permease protein EF0909 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 29376807 Common - toprim domain protein EF2305 11 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 29375291 Common - PTS system, fructose-specific family, IIBC components EF0694 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 29377248 Common thiD phosphomethylpyrimidine kinase EF2775 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 29375888 Common - ABC transporter, ATP-binding protein EF1320 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29377774 Common rpmH 50S ribosomal protein L34 EF3333 191 None None None 29376501 Common - recombination factor protein RarA EF1979 247 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 29375738 Common - helicase, putative EF1162 92 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 29374968 Common - hypothetical protein EF0329 13 None None None 29376844 Common - FtsK/SpoIIIE family protein EF2343 77 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 29374799 Common - aggregation substance, putative EF0149 9 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376870 Common aspB aspartate aminotransferase EF2372 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 29374693 Common - hypothetical protein EF0035 4 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 29376009 Pathogen - DNA topoisomerase domain protein EF1442 1 None None None 29377027 Pathogen - hypothetical protein EF2538 1 None None None 29377614 Common - methionine sulfoxide reductase B EF3164 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 29377168 Common - Snf2 family protein EF2688 152 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 29375574 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase EF0992 218 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 29375466 Common - hypothetical protein EF0881 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 29376610 Pathogen - hypothetical protein EF2101 1 None None None 29376788 Common - hypothetical protein EF2285 4 None None None 29376882 Pathogen - hypothetical protein EF2385 1 None None None 29376248 Common rpsP ribosomal protein S16 EF1694 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 29377461 Common - allantoin permease EF3000 65 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 29376447 Common - acetyltransferase, GNAT family EF1919 8 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 29374997 Common - glyoxalase family protein EF0358 37 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 29377450 Common - hypothetical protein EF2987 24 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 29375798 Common - thiamin biosynthesis ApbE, putative EF1225 133 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 29375598 Common - PTS system, IIA component EF1018 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 29375715 Common - glutamine amidotransferase, class I EF1139 120 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 29376662 Common - ABC transporter, ATP-binding protein EF2153 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 29374976 Pathogen - hypothetical protein EF0337 1 None None None 29376868 Common - oxidoreductase, Gfo/Idh/MocA family EF2370 170 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 29377102 Common vacB ribonuclease R EF2617 194 COG0557 VacB, Exoribonuclease R Transcription 29376107 Common - hypothetical protein EF1544 8 COG4955 COG4955, Uncharacterized protein conserved in bacteria Function unknown 29374751 Common serS-1 seryl-tRNA synthetase EF0100 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376375 Common lacB galactose-6-phosphate isomerase subunit LacB EF1834 108 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 29376391 Common - transposase, IS256 family EF1855 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29377460 Common - allantoinase EF2999 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 29375443 Common - hypothetical protein EF0855 4 None None None 29375556 Common pepQ-1 proline dipeptidase EF0973 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 29375046 Common - PTS system, mannitol-specfic IIBC components EF0411 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 29375007 Common - hydrolase, haloacid dehalogenase-like family EF0369 194 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 29375910 Common - sugar ABC transporter, permease protein EF1343 152 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 29376675 Common - glycosyl transferase, group 2 family protein EF2167 65 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29377709 Common - Ham1 family protein, putative EF3266 231 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 29376947 Common - hypothetical protein EF2453 11 COG4471 COG4471, Uncharacterized protein conserved in bacteria Function unknown 29376717 Common - hypothetical protein EF2210 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 29376928 Common - phosphosugar-binding transcriptional regulator, RpiR family EF2434 129 COG1737 RpiR, Transcriptional regulators Transcription 29375769 Common vicK sensory box histidine kinase VicK EF1194 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 29375399 Common - hypothetical protein EF0810 18 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 29376225 Common - oxidoreductase, zinc-binding EF1671 202 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 29375138 Common ssb-3 single-strand binding protein EF0510 204 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 29374925 Common - fibronectin-binding protein, putative EF0286 7 None None None 29376073 Pathogen - hypothetical protein EF1506 1 None None None 29376693 Common - ISEf1, transposase EF2185 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29377307 Common - DnaD domain protein EF2839 8 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 29377340 Common - hydrolase, HAD subfamily IIIA EF2874 45 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 29376205 Common - abortive infection protein EF1651 25 None None None 29375121 Common - hypothetical protein EF0493 3 None None None 29374914 Common - hypothetical protein EF0274 13 COG2267 PldB, Lysophospholipase Lipid metabolism 29376347 Common - PTS system, IIC component EF1803 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29375601 Common - hypothetical protein EF1021 26 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 29375739 Common - L-asparaginase, putative EF1163 139 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 29376970 Common - hypothetical protein EF2477 25 COG4260 COG4260, Putative virion core protein (lumpy skin disease virus) Function unknown 29377523 Common rpsO ribosomal protein S15 EF3065 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 29376372 Common - PTS system, IID component EF1829 39 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29377612 Common - hypothetical protein EF3161 2 None None None 29374872 Common adk adenylate kinase EF0228 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 29377360 Common - aminotransferase, class II EF2895 233 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 29375482 Pathogen - hypothetical protein EF0898 1 None None None 29375097 Common nagB glucosamine-6-phosphate isomerase EF0466 89 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 29375697 Common murI glutamate racemase EF1121 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 29375908 Common - ABC transporter, ATP-binding/permease protein EF1341 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29376031 Common - hypothetical protein EF1464 2 None None None 29377423 Common - ribose uptake protein, putative EF2959 11 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 29376100 Common - hypothetical protein EF1536 80 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 29375173 Common xylA xylose isomerase EF0556 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 29375985 Pathogen - hypothetical protein EF1418 1 None None None 29377096 Common atpH ATP synthase F1, delta subunit EF2611 156 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 29377325 Common - penicillin-binding protein 2B EF2857 192 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 29375136 Common - hypothetical protein EF0508 5 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 29375164 Common - hypothetical protein EF0546 13 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 29374708 Common - hypothetical protein EF0050 19 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 29377161 Common - ABC transporter, ATP-binding/permease protein EF2680 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375000 Common - chitinase, family 2 EF0361 22 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 29376826 Pathogen - hypothetical protein EF2325 1 None None None 29377061 Common - endoribonuclease L-PSP, putative EF2574 180 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 29375080 Common - hydrolase, alpha/beta hydrolase fold family EF0449 110 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 29374771 Common - hypothetical protein EF0120 6 COG2096 COG2096, Uncharacterized conserved protein Function unknown 29377714 Pathogen - hypothetical protein EF3271 1 None None None 29376429 Common - Mn2+/Fe2+ transporter, NRAMP family EF1901 97 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 29375901 Pathogen - AgrC domain protein EF1334 3 None None None 29376987 Common uppS undecaprenyl diphosphate synthase EF2495 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 29374907 Common - chaperonin, 33 kDa EF0266 137 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 29375872 Common - magnesium-translocating P-type ATPase EF1304 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 29377113 Common - N-acetylmuramoyl-L-alanine amidase, family 4 EF2628 74 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 29376459 Pathogen - hypothetical protein EF1933 1 None None None 29374823 Common pyn pyrimidine-nucleoside phosphorylase EF0173 129 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 29375118 Pathogen - cell wall surface anchor family protein EF0490 2 COG5373 COG5373, Predicted membrane protein Function unknown 29374879 Common - hypothetical protein EF0235 7 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 29374817 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein EF0167 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 29376721 Common - glyoxylase family protein EF2214 47 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 29376751 Pathogen - hypothetical protein EF2245 1 None None None 29377430 Common - transcriptional antiterminator, bglG family EF2966 47 COG3711 BglG, Transcriptional antiterminator Transcription 29376741 Common - sugar ABC transporter, sugar-binding protein, putative EF2234 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 29377347 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase EF2881 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29376036 Common - hypothetical protein EF1469 13 None None None 29377083 Common - glycosyl hydrolase, family 1 EF2597 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 29376529 Pathogen - coenzyme F420 hydrogenase domain protein EF2014 1 None None None 29375344 Common - hypothetical protein EF0751 7 None None None 29375962 Common - molybdenum cofactor biosynthesis family protein EF1395 183 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 29375005 Common - hypothetical protein EF0367 5 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 29377622 Common cinA competence/damage-inducible protein CinA EF3172 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 29376299 Common - endo/excinuclease amino terminal domain protein EF1750 222 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 29376434 Common - hypothetical protein EF1906 126 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 29375264 Pathogen - hypothetical protein EF0665 1 None None None 29374936 Common copY transcriptional repressor CopY EF0297 39 COG3682 COG3682, Predicted transcriptional regulator Transcription 29374668 Common rpsF 30S ribosomal protein S6 EF0007 183 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 29375700 Common - transcriptional regulator, DeoR family EF1124 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 29375589 Common - oxidoreductase, Gfo/Idh/MocA family EF1008 101 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 29375976 Common - hypothetical protein EF1409 36 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 29377680 Common - type III leader peptidase family EF3236 96 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 29377383 Common - ABC transporter, ATP-binding/permease protein EF2919 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29376141 Common - iron-sulfur cluster-binding protein, putative EF1578 142 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 29376522 Pathogen - hypothetical protein EF2006 1 None None None 29375828 Common - hydrolase, haloacid dehalogenase-like family EF1259 113 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 29376908 Common - HD domain protein EF2413 56 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 29374835 Common deoD-2 purine nucleoside phosphorylase EF0187 99 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 29377414 Pathogen - hypothetical protein EF2950 1 None None None 29375546 Pathogen - hypothetical protein EF0963 1 None None None 29374733 Common - gls24 protein EF0080 34 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 29374784 Common - hypothetical protein EF0133 2 None None None 29376530 Common - minor head protein, putative EF2015 8 None None None 29375767 Common - aquaporin Z EF1192 135 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 29377311 Pathogen - hypothetical protein EF2843 1 None None None 29375933 Common - hypothetical protein EF1366 39 COG1434 COG1434, Uncharacterized conserved protein Function unknown 29375437 Common alr alanine racemase EF0849 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 29375868 Common - cell division protein, FtsW/RodA/SpovE family EF1300 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 29376352 Common - agaS protein EF1808 27 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 29374939 Common - hypothetical protein EF0300 2 COG4194 COG4194, Predicted membrane protein General function prediction only 29377558 Pathogen - hypothetical protein EF3102 1 None None None 29376771 Common - PTS system, IIA component EF2267 32 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29377736 Common - hypothetical protein EF3295 8 COG4858 COG4858, Uncharacterized membrane-bound protein conserved in bacteria Function unknown 29376851 Common - transcriptional regulator, Cro/CI family EF2350 5 None None None 29375996 Pathogen - hypothetical protein EF1429 1 None None None 29376053 Common ply-2 endolysin EF1486 7 COG5632 COG5632, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 29375383 Common - ABC transporter, ATP-binding protein EF0793 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29377437 Common - MutS2 family protein EF2974 201 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 29374837 Common - ferrichrome ABC transporter, ATP-binding protein EF0191 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 29377692 Pathogen - hypothetical protein EF3249 1 None None None 29377263 Common - 5-formyltetrahydrofolate cyclo-ligase family protein EF2791 110 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 29377281 Common - hypothetical protein EF2812 2 COG4722 COG4722, Phage-related protein Function unknown 29377355 Common - glycosyl transferase, group 1 family protein EF2890 198 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 29375228 Pathogen - hypothetical protein EF0626 1 None None None 29376993 Common - arsenate reductase, putative EF2501 90 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 29377046 Common - pyruvate flavodoxin/ferredoxin oxidoreductase family protein EF2559 123 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 29377029 Common - hypothetical protein EF2540 3 None None None 29377596 Common - 6-phosphogluconate dehydrogenase-like protein EF3142 192 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 29377722 Common - peptidase, U32 family EF3279 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 29376695 Common - IS256, transposase EF2187 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29377480 Common - hypothetical protein EF3020 67 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29377598 Pathogen - hypothetical protein EF3145 1 None None None 29376919 Common - phosphoglucomutase/phosphomannomutase family protein EF2425 229 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 29376579 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase EF2070 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 29376027 Pathogen - LysM domain protein EF1460 1 None None None 29375255 Common - glyoxalase family protein EF0656 42 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 29376090 Common - transcriptional regulator, Fur family EF1525 197 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 29375361 Common - hypothetical protein EF0768 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 29377591 Common - PTS system, IIB component EF3137 35 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29374723 Common ruvB Holliday junction DNA helicase B EF0067 220 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 29374720 Common - hypothetical protein EF0064 12 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 29374895 Common - aldehyde dehydrogenase EF0253 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 29375233 Common - cardiolipin synthetase, putative EF0631 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 29377033 Common - transcriptional regulator, Cro/CI family EF2544 25 COG1476 COG1476, Predicted transcriptional regulators Transcription 29376309 Common - cell division ABC transporter, permease protein FtsX, putative EF1760 116 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 29376625 Pathogen - hypothetical protein EF2116 1 None None None 29375257 Common - hypothetical protein EF0658 8 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 29375358 Pathogen - hypothetical protein EF0765 1 None None None 29377274 Common - holin EF2803 2 None None None 29377633 Common - cell wall surface anchor family protein, putative EF3183 8 None None None 29376858 Pathogen - hypothetical protein EF2360 1 None None None 29377170 Common sbcD exonuclease SbcD EF2690 145 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 29374846 Common fusA elongation factor G EF0200 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 29375938 Common - hypothetical protein EF1371 105 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 29377479 Common - hypothetical protein EF3019 8 None None None 29376640 Common - hypothetical protein EF2131 5 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 29376728 Common - ABC transporter, substrate-binding protein EF2221 8 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 29377610 Common - hydrolase, haloacid dehalogenase-like family EF3158 179 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 29375091 Common - hypothetical protein EF0460 83 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 29376292 Common pepQ-2 proline dipeptidase EF1743 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 29377359 Common - general stress protein 13, putative EF2894 240 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 29377673 Common - Rep protein EF3226 5 None None None 29377362 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type EF2898 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 29376279 Common ebsB EbsB protein EF1728 34 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 29376955 Common - inositol monophosphatase protein family EF2461 191 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 29376831 Pathogen - hypothetical protein EF2330 1 None None None 29375555 Common - DNA repair exonuclease family protein EF0972 105 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 29377600 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase EF3148 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 29376148 Common nox NADH oxidase EF1586 225 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 29375841 Common - hypothetical protein EF1272 40 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 29376477 Common - PTS system, IID component EF1952 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29376267 Common pyrDII dihydroorotate dehydrogenase electron transfer subunit EF1715 106 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 29376572 Common - transcriptional regulator, AraC family EF2063 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 29374854 Common rplB 50S ribosomal protein L2 EF0209 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 29376683 Common - licD-related protein EF2175 14 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 29376153 Common - ABC transporter, ATP-binding/permease protein EF1592 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29376811 Pathogen - hypothetical protein EF2309 1 None None None 29375506 Common - hypothetical protein EF0922 119 COG2855 COG2855, Predicted membrane protein Function unknown 29375688 Common rexB exonuclease RexB EF1112 24 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 29374985 Pathogen - hypothetical protein EF0346 1 None None None 29374801 Pathogen - hypothetical protein EF0151 1 None None None 29375441 Pathogen - hypothetical protein EF0853 1 None None None 29377217 Common lplA-2 lipoate-protein ligase A EF2741 83 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 29376331 Common purS phosphoribosylformylglycinamidine synthase, PurS protein EF1784 100 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 29375516 Pathogen - hypothetical protein EF0932 1 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 29376255 Common phoP alkaline phosphatase synthesis transcriptional regulatory protein PhoP EF1703 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376898 Common acyP acylphosphatase EF2401 89 COG1254 AcyP, Acylphosphatases Energy production and conversion 29377012 Pathogen - hypothetical protein EF2523 1 None None None 29375469 Common - hypothetical protein EF0884 6 None None None 29377204 Common - phosphosugar-binding transcriptional regulator, putative EF2727 11 COG1737 RpiR, Transcriptional regulators Transcription 29374752 Common - hydrolase, alpha/beta hydrolase fold family EF0101 69 COG2267 PldB, Lysophospholipase Lipid metabolism 29377406 Pathogen - hypothetical protein EF2942 1 None None None 29375350 Common - hypothetical protein EF0757 5 None None None 29376762 Common - hypothetical protein EF2258 8 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 29375810 Common - hypothetical protein EF1237 26 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 29377585 Common - hypothetical protein EF3131 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 29374830 Common - ABC transporter, permease protein EF0180 136 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 29376901 Common glyS glycyl-tRNA synthetase, beta subunit EF2406 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 29374663 Common dnaN DNA polymerase III, beta subunit EF0002 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 29375305 Pathogen - hypothetical protein EF0708 1 None None None 29375834 Common - hypothetical protein EF1265 127 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 29375794 Common - spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein EF1221 102 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 29376366 Common - N-acetylmuramoyl-L-alanine amidase EF1823 62 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 29376514 Common - holin EF1993 6 COG5546 COG5546, Small integral membrane protein Function unknown 29376044 Common - hypothetical protein EF1477 3 None None None 29377544 Pathogen - hypothetical protein EF3087 1 None None None 29375313 Common - PTS system, fructose-specific family, IIABC components EF0717 142 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 29377735 Common - hypothetical protein EF3294 6 COG5617 COG5617, Predicted integral membrane protein Function unknown 29376402 Pathogen - hypothetical protein EF1872 2 None None None 29375530 Common - hypothetical protein EF0946 6 COG4894 COG4894, Uncharacterized conserved protein Function unknown 29377551 Common ftsY signal recognition particle-docking protein FtsY EF3094 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 29375536 Pathogen - hypothetical protein EF0953 1 None None None 29376466 Common - cyclic AMP receptor protein, putative EF1940 50 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 29376887 Common - hypothetical protein EF2390 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 29376968 Common - hypothetical protein EF2475 151 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 29377497 Common - hypothetical protein EF3039 7 COG5584 COG5584, Predicted small secreted protein Function unknown 29375112 Pathogen - hypothetical protein EF0482 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 29377747 Common - PTS system, sorbitol-specific IIBC components EF3306 22 COG3732 SrlE, Phosphotransferase system sorbitol-specific component IIBC Carbohydrate transport and metabolism 29376464 Common - cation-transporting ATPase, E1-E2 family EF1938 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 29376334 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit EF1787 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 29375405 Common - PTS system, IIC component EF0816 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29375776 Common - hypothetical protein EF1201 31 COG2966 COG2966, Uncharacterized conserved protein Function unknown 29375565 Common - transcriptional regulator, ArgR family EF0983 55 COG1438 ArgR, Arginine repressor Transcription 29376891 Common - ABC transporter, ATP-binding protein EF2394 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 29375271 Common - hypothetical protein EF0673 11 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 29377768 Common - citrate transporter EF3327 35 COG2851 CitM, H+/citrate symporter Energy production and conversion 29377563 Common - peptide ABC transporter, permease protein EF3107 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 29374860 Common rpsQ 30S ribosomal protein S17 EF0215 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 29376133 Common - DegV family protein EF1570 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 29377625 Common - rrf2 family protein EF3175 62 COG1959 COG1959, Predicted transcriptional regulator Transcription 29374957 Pathogen - hypothetical protein EF0318 1 None None None 29375178 Pathogen - hypothetical protein EF0564 1 None None None 29377050 Common - hypothetical protein EF2563 25 None None None 29374787 Pathogen - hypothetical protein EF0136 1 None None None 29377388 Common - metallo-beta-lactamase superfamily protein EF2924 159 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 29376084 Common - hypothetical protein EF1518 8 None None None 29376011 Common - hypothetical protein EF1444 5 None None None 29375298 Common prfC peptide chain release factor 3 EF0701 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 29376424 Common - cell wall surface anchor family protein EF1896 10 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29375721 Common - hypothetical protein EF1145 13 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 29376565 Common ubiA prenyltransferase EF2056 25 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 29376189 Common - response regulator EF1633 223 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 29376416 Pathogen - hypothetical protein EF1887 2 None None None 29375182 Common kdpC potassium-transporting ATPase, subunit C EF0569 94 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 29375916 Common - glycosyl hydrolase, family 13 EF1349 172 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 29376488 Common - YitT family protein EF1966 49 COG1284 COG1284, Uncharacterized conserved protein Function unknown 29377141 Common - hypothetical protein EF2657 11 COG4684 COG4684, Predicted membrane protein Function unknown 29374810 Common - hypothetical protein EF0160 6 None None None 29374713 Common - adhesion lipoprotein EF0055 181 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 29377298 Pathogen - hypothetical protein EF2830 1 None None None 29377318 Common - hypothetical protein EF2850 4 None None None 29375724 Common - penicillin-binding protein 1A EF1148 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 29376383 Pathogen - hypothetical protein EF1844 1 None None None 29375666 Common - hypothetical protein EF1090 4 None None None 29376961 Pathogen - hypothetical protein EF2467 1 None None None 29375796 Common - chlorohydrolase family protein EF1223 173 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 29377256 Common - hypothetical protein EF2784 5 None None None 29374951 Pathogen - aspartate 1-decarboxylase domain protein EF0312 1 None None None 29375158 Common - phosphosugar-binding transcriptional regulator, RpiR family EF0539 132 COG1737 RpiR, Transcriptional regulators Transcription 29375612 Common - 6-aminohexanoate-cyclic-dimer hydrolase, putative EF1033 216 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 29376606 Pathogen - hypothetical protein EF2097 1 None None None 29375025 Common allD ureidoglycolate dehydrogenase EF0388 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 29375445 Common - hypothetical protein EF0857 3 None None None 29376688 Common - glycosyl transferase, group 2 family protein EF2180 187 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 29375764 Common - hypothetical protein EF1189 9 COG4478 COG4478, Predicted membrane protein Function unknown 29375151 Common cylM cylM protein EF0527 16 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 29376659 Common - FemAB family protein EF2150 15 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 29377264 Common - hypothetical protein EF2792 19 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 29375052 Common - hypothetical protein EF0419 7 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 29377148 Common - RNA methyltransferase, TrmH family EF2665 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 29375456 Common - transcriptional regulator, Cro/CI family EF0869 58 COG1476 COG1476, Predicted transcriptional regulators Transcription 29376283 Common - ABC transporter, ATP-binding/permease protein, MDR family EF1733 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375876 Common dnaK dnak protein EF1308 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 29375326 Common - transcriptional regulator, luxR family EF0731 61 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 29377200 Common sdhA-2 L-serine dehydratase, iron-sulfur-dependent, alpha subunit EF2722 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 29376075 Common - hypothetical protein EF1508 2 None None None 29377719 Common - hypothetical protein EF3276 33 COG3535 COG3535, Uncharacterized conserved protein Function unknown 29377728 Common - PTS system, IIC component EF3285 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29376346 Common - PTS system, IID component EF1802 39 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29376764 Pathogen - hypothetical protein EF2260 2 None None None 29377516 Common - phosphotyrosine protein phosphatase EF3058 137 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 29376297 Common lgt prolipoprotein diacylglyceryl transferase EF1748 188 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 29376914 Common thrB homoserine kinase EF2420 124 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 29377122 Common - redox-sensing transcriptional repressor Rex EF2638 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 29374765 Common - glycosyl hydrolase, family 20 EF0114 11 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 29377631 Common - hypothetical protein EF3181 4 COG3711 BglG, Transcriptional antiterminator Transcription 29375415 Common - oxidoreductase, Gfo/Idh/MocA family EF0827 165 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 29377236 Common holB DNA polymerase III subunit delta' EF2762 223 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 29375497 Common - transposase, putative EF0913 64 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 29375920 Common pdhA pyruvate dehydrogenase complex E1 component, alpha subunit EF1353 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 29375753 Pathogen - hypothetical protein EF1177 1 None None None 29377157 Common - competence protein, putative EF2675 11 COG4469 CoiA, Competence protein General function prediction only 29376178 Common - carbon dioxide concentrating mechanism protein CcmL, putative EF1619 39 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 29376551 Common - transcriptional regulator, Cro/CI family EF2040 17 None None None 29375859 Common - structural protein, putative EF1290 7 None None None 29377643 Common - murein hydrolase regulator LrgA EF3194 20 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 29375640 Common - deaminase EF1061 61 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 29376186 Common eutC ethanolamine ammonia-lyase small subunit EF1627 52 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 29377207 Common secE preprotein translocase, SecE subunit EF2730 10 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 29375512 Common - glucose uptake protein EF0928 16 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 29377057 Common - aldehyde oxidoreductase, putative EF2570 123 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 29376187 Common eutB ethanolamine ammonia-lyase large subunit EF1629 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 29375945 Common - transcriptional regulator, putative EF1378 2 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376440 Common - ROK family protein EF1912 155 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 29377089 Pathogen - hypothetical protein EF2604 1 None None None 29374754 Common - transcriptional regulator, ArgR family EF0103 53 COG1438 ArgR, Arginine repressor Transcription 29377090 Common murAA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 EF2605 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 29376163 Common scrB-1 sucrose-6-phosphate dehydrogenase EF1603 52 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 29376146 Common cysK cysteine synthase A EF1584 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 29376449 Common - ribonucleoside hydrolase RihC EF1921 86 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 29375142 Common - hypothetical protein EF0516 15 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 29375064 Common - transcriptional regulator, AraC family EF0432 93 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 29375850 Pathogen - hypothetical protein EF1281 1 None None None 29376436 Common murC UDP-N-acetylmuramate--L-alanine ligase EF1908 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 29375100 Common - hypothetical protein EF0469 78 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 29375990 Common - transcriptional regulator, Cro/CI family EF1423 6 COG1476 COG1476, Predicted transcriptional regulators Transcription 29375999 Pathogen - hypothetical protein EF1432 1 None None None 29376195 Common - iron compound ABC transporter, permease protein EF1640 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 29376652 Common - hypothetical protein EF2143 7 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29377198 Common - ABC transporter, ATP-binding protein EF2720 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 29376671 Common - glycerophosphoryl diester phosphodiesterase, putative EF2163 171 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 29376975 Pathogen - hypothetical protein EF2483 1 None None None 29376192 Common - ATP:cob(I)alamin adenosyltransferase, putative EF1637 128 COG2096 COG2096, Uncharacterized conserved protein Function unknown 29376218 Common - hypothetical protein EF1664 52 COG1434 COG1434, Uncharacterized conserved protein Function unknown 29375679 Common - amino acid permease family protein EF1103 106 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 29375144 Pathogen - cell wall surface anchor family protein EF0518 2 None None None 29377425 Common rbsK ribokinase EF2961 216 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 29377500 Common - PTS system, IID component EF3042 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29376273 Common pyrR pyrimidine regulatory protein PyrR EF1721 127 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 29375647 Common galK galactokinase EF1069 96 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 29377433 Common - hypothetical protein EF2969 8 None None None 29377581 Common rpoZ DNA-directed RNA polymerase subunit omega EF3126 18 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 29377444 Common - sigma-54 dependent DNA-binding response regulator EF2981 159 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 29375592 Common - PTS system, IIB component EF1012 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 29377530 Common - BioY family protein EF3072 92 COG1268 BioY, Uncharacterized conserved protein General function prediction only 29376558 Common - amino acid permease family protein EF2047 194 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 29377131 Common - permease, GntP family EF2647 71 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 29377137 Common - transcriptional regulator, Cro/CI family EF2653 110 COG1396 HipB, Predicted transcriptional regulators Transcription 29375709 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase EF1133 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 29375397 Pathogen - hypothetical protein EF0808 1 None None None 29377097 Common atpF ATP synthase F0, B subunit EF2612 175 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 29375644 Common - hexapeptide-repeat containing-acetyltransferase EF1066 202 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 29377653 Common - hypothetical protein EF3205 7 None None None 29375653 Common - acetyltransferase, GNAT family EF1075 6 COG0456 RimI, Acetyltransferases General function prediction only 29375377 Common - tributyrin esterase, putative EF0786 19 COG0627 COG0627, Predicted esterase General function prediction only 29377009 Pathogen - hypothetical protein EF2520 1 None None None 29376866 Pathogen - hypothetical protein EF2368 1 None None None 29376380 Common lacR lactose phosphotransferase system repressor LacR EF1839 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 29376066 Common - V-type ATP synthase subunit B EF1499 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 29375825 Common - ABC transporter, permease protein EF1254 107 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 29377373 Common - hypothetical protein EF2909 7 COG4841 COG4841, Uncharacterized protein conserved in bacteria Function unknown 29377225 Common - hypothetical protein EF2750 5 None None None 29375075 Common - LysM domain protein EF0443 8 None None None 29377163 Common - hypothetical protein EF2682 8 None None None 29374905 Common hpt hypoxanthine-guanine phosphoribosyltransferase EF0264 157 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 29376711 Common - transcriptional regulator, TetR family EF2203 13 COG1309 AcrR, Transcriptional regulator Transcription 29377638 Common - hypothetical protein EF3188 83 None None None 29375894 Common - BadF/BadG/BcrA/BcrD ATPase family protein EF1327 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 29376228 Pathogen - hypothetical protein EF1674 1 None None None 29374781 Pathogen - hypothetical protein EF0130 1 None None None 29375471 Common - hypothetical protein EF0886 5 COG5298 COG5298, Uncharacterized protein conserved in bacteria Function unknown 29376456 Common glpK glycerol kinase EF1929 180 COG0554 GlpK, Glycerol kinase Energy production and conversion 29377030 Common - hypothetical protein EF2541 2 None None None 29375695 Common - amino acid ABC transporter, amino acid-binding protein EF1119 174 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 29377241 Common - transcriptional regulator EF2767 77 COG0819 TenA, Putative transcription activator Transcription 29376370 Common - hypothetical protein EF1827 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 29376000 Common - hypothetical protein EF1433 55 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 29375161 Common - hypothetical protein EF0543 16 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 29376691 Common - ABC transporter, permease protein EF2183 124 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 29376669 Common - GTP-binding protein EF2161 216 COG2262 HflX, GTPases General function prediction only 29375390 Common leuS leucyl-tRNA synthetase EF0801 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376450 Common - transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein EF1922 176 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 29375603 Common - hypothetical protein EF1023 5 COG1359 COG1359, Uncharacterized conserved protein Function unknown 29377323 Common - site-specific recombinase, phage integrase family EF2855 115 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29376949 Common - hypothetical protein EF2455 7 None None None 29376532 Common - terminase, large subunit, putative EF2017 25 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 29377075 Common - hypothetical protein EF2588 18 None None None 29374916 Common ogt methylated-DNA--protein-cysteine S-methyltransferase EF0277 219 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 29375593 Common - PTS system, IIC component EF1013 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29377661 Common - PTS system, IID component EF3213 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29375690 Common - hypothetical protein EF1114 140 COG1733 COG1733, Predicted transcriptional regulators Transcription 29375427 Common - hypothetical protein EF0839 15 None None None 29376269 Common pyraA carbamoyl phosphate synthase small subunit EF1717 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 29374766 Common - endoribonuclease L-PSP, putative EF0115 170 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 29375710 Common - peptidase, M20/M25/M40 family EF1134 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 29375134 Pathogen - hypothetical protein EF0506 1 None None None 29375773 Common - hypothetical protein EF1198 96 COG0701 COG0701, Predicted permeases General function prediction only 29374844 Common rpsL 30S ribosomal protein S12 EF0198 235 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 29376318 Common - conserved hypothetical protein TIGR00257 EF1771 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 29375906 Common - hypothetical protein EF1339 9 None None None 29375166 Common - hypothetical protein EF0548 15 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 29377521 Pathogen - immunity protein, putative EF3063 1 None None None 29377675 Common rpsI 30S ribosomal protein S9 EF3230 245 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 29376305 Common - phosphate ABC transporter, ATP-binding protein EF1756 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 29374874 Common rpmJ 50S ribosomal protein L36 EF0230 139 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 29376427 Common trmD tRNA (guanine-N1)-methyltransferase EF1899 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 29377489 Common - PTS system, IIC component EF3030 39 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29376985 Common - teichoic acid biosynthesis protein, putative EF2493 34 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 29376615 Pathogen - hypothetical protein EF2106 1 None None None 29376420 Common - FtsK/SpoIIIE family protein EF1892 7 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 29375746 Common rho transcription termination factor Rho EF1170 202 COG1158 Rho, Transcription termination factor Transcription 29375168 Common - glycosyl hydrolase, family 31 EF0551 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 29377367 Common - ABC transporter, substrate-binding protein EF2903 106 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 29374927 Pathogen - hypothetical protein EF0288 1 None None None 29377509 Common - hypothetical protein EF3051 3 None None None 29376373 Common - PTS system, IIC component EF1830 32 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29376583 Common - ABC transporter, ATP-binding protein EF2074 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 29376597 Pathogen - hypothetical protein EF2088 1 None None None 29377338 Common - conserved hypothetical protein TIGR00253 EF2872 94 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 29375785 Common - transcriptional regulator EF1212 63 COG1316 LytR, Transcriptional regulator Transcription 29376828 Common - hypothetical protein EF2327 3 None None None 29374995 Pathogen - hypothetical protein EF0356 1 None None None 29374675 Common - DegV family protein EF0016 57 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 29374884 Common - hypothetical protein EF0241 106 COG0393 COG0393, Uncharacterized conserved protein Function unknown 29375542 Pathogen - hypothetical protein EF0959 1 None None None 29375246 Common - exfoliative toxin A, putative EF0645 32 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 29375489 Common - pentapeptide repeat family protein EF0905 36 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 29375732 Common - transcriptional regulator, GntR family EF1156 129 COG2188 PhnF, Transcriptional regulators Transcription 29376200 Common hslU ATP-dependent protease ATP-binding subunit EF1646 210 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 29375959 Common moaC molybdenum cofactor biosynthesis protein MoaC EF1392 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 29377291 Pathogen - portal protein EF2822 3 None None None 29376543 Common - hypothetical protein EF2031 4 None None None 29376539 Common - transcriptional regulator, ArpU family EF2024 4 None None None 29376243 Pathogen - hypothetical protein EF1689 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 29375952 Common - molybdopterin-guanine dinucleotide biosynthesis protein A, putative EF1385 96 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 29376613 Pathogen - hypothetical protein EF2104 1 None None None 29377176 Common - MutT/nudix family protein EF2696 183 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 29377668 Common - transcriptional regulator, Cro/CI family EF3221 4 COG3655 COG3655, Predicted transcriptional regulator Transcription 29376924 Common - xanthine/uracil permease family protein EF2430 137 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 29374859 Common rpmC ribosomal protein L29 EF0214 169 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 29376326 Common purN phosphoribosylglycinamide formyltransferase EF1779 227 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 29374743 Pathogen - hypothetical protein EF0092 1 None None None 29374793 Pathogen - hypothetical protein EF0142 1 None None None 29375982 Common gdhA glutamate dehydrogenase EF1415 169 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 29376507 Common comG6 competence protein EF1986 4 COG4940 ComGF, Competence protein ComGF Intracellular trafficking and secretion 29376897 Common - RNA methyltransferase, TrmH family EF2400 211 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 29375495 Common - peptide ABC transporter, ATP-binding protein EF0911 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 29375171 Common - PTS system, IIB component EF0554 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29377499 Common - pheromone binding protein EF3041 194 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29376821 Common - hypothetical protein EF2319 2 None None None 29376942 Common - comE operon protein 2, putative EF2448 88 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 29375459 Common - transcriptional regulator, Cro/CI family EF0873 6 COG1396 HipB, Predicted transcriptional regulators Transcription 29376357 Common - sulfatase domain protein EF1813 54 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 29377182 Pathogen - hypothetical protein EF2702 1 None None None 29375801 Common - hypothetical protein EF1228 4 None None None 29376809 Common - hypothetical protein EF2307 34 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 29374892 Common - maltose O-acetyltransferase, putative EF0250 79 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 29375717 Common - MutT/nudix family protein EF1141 6 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 29374702 Common cysE serine O-acetyltransferase EF0044 208 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 29376842 Common - hypothetical protein EF2341 3 None None None 29375484 Common adhE aldehyde-alcohol dehydrogenase EF0900 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 29375464 Common fpg formamidopyrimidine-DNA glycosylase EF0879 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 29376884 Common - chromosome partitioning ATPase, ParA family EF2387 205 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 29376126 Common aroB 3-dehydroquinate synthase EF1563 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 29375525 Common - ABC transporter, ATP-binding/permease protein EF0941 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375881 Common - hypothetical protein EF1313 13 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 29374990 Common - structural protein, putative EF0351 4 None None None 29377616 Common mutL DNA mismatch repair protein EF3166 192 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 29376604 Pathogen - hypothetical protein EF2095 1 None None None 29376109 Pathogen - LysM domain protein EF1546 1 COG5028 COG5028, Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 Intracellular trafficking and secretion 29376237 Common - Lipase/Acylhydrolase, putative EF1683 12 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 29374803 Pathogen - cell wall surface anchor family protein EF0153 2 COG5373 COG5373, Predicted membrane protein Function unknown 29377044 Common - fumarate reductase flavoprotein subunit EF2556 225 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 29376801 Common vanSB sensor histidine kinase VanSB EF2298 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 29375231 Common - oxidoreductase, aldo/keto reductase family EF0629 191 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 29375703 Common ulaA ascorbate-specific PTS system enzyme IIC EF1127 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 29376584 Common - ABC transporter, permease protein EF2075 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 29376837 Pathogen - hypothetical protein EF2336 5 None None None 29377283 Pathogen - hypothetical protein EF2814 2 None None None 29375215 Pathogen - hypothetical protein EF0610 1 None None None 29374725 Common - N-acetylmannosamine-6-phosphate 2-epimerase EF0069 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 29375553 Common rpmA 50S ribosomal protein L27 EF0970 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 29377553 Common - chromosome partition protein SMC EF3096 206 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 29376369 Common - alcohol dehydrogenase EF1826 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 29376876 Common proS prolyl-tRNA synthetase EF2379 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376034 Common - hypothetical protein EF1467 2 None None None 29375238 Common - hypothetical protein EF0637 2 None None None 29375249 Common - nitroreductase family protein EF0648 63 COG0778 NfnB, Nitroreductase Energy production and conversion 29376933 Common uppP undecaprenyl pyrophosphate phosphatase EF2439 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 29376013 Pathogen - hypothetical protein EF1446 1 None None None 29375925 Common gldA glycerol dehydrogenase EF1358 94 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 29376324 Common purD phosphoribosylamine--glycine ligase EF1777 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 29374833 Common deoB phosphopentomutase EF0185 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 29376307 Common - phosphate ABC transporter, permease protein EF1758 230 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 29376719 Common - hypothetical protein EF2212 6 None None None 29377309 Common - recT protein, putative EF2841 13 COG3723 RecT, Recombinational DNA repair protein (RecE pathway) DNA replication, recombination, and repair 29376570 Common cydA cytochrome d ubiquinol oxidase, subunit I EF2061 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 29377172 Common - hypothetical protein EF2692 85 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 29377686 Common - abortive phage resistance protein, putative EF3242 28 COG1106 COG1106, Predicted ATPases General function prediction only 29377357 Pathogen - hypothetical protein EF2892 1 None None None 29375475 Pathogen - hypothetical protein EF0890 1 None None None 29375356 Common uvrA excinuclease ABC, subunit A EF0763 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 29376963 Common - HD domain protein EF2470 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 29376995 Common - hypothetical protein EF2503 6 None None None 29376094 Common - PTS system, IIC component, putative EF1529 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29376953 Common recQ-2 ATP-dependent DNA helicase RecQ EF2459 235 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 29375070 Common - hypothetical protein EF0438 11 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 29377035 Common - site-specific recombinase, phage integrase family EF2546 102 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29376281 Common aroD 3-dehydroquinate dehydratase EF1731 55 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 29376414 Pathogen - hypothetical protein EF1885 1 None None None 29377561 Pathogen - hypothetical protein EF3105 1 None None None 29375266 Common - hypothetical protein EF0667 21 COG0400 COG0400, Predicted esterase General function prediction only 29377334 Common - hypothetical protein EF2867 26 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 29375370 Common - glycerophosphoryl diester phosphodiesterase family protein EF0779 53 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 29377353 Common - hypothetical protein EF2888 8 COG4703 COG4703, Uncharacterized protein conserved in bacteria Function unknown 29375093 Common - hypothetical protein EF0462 2 COG5521 COG5521, Predicted integral membrane protein Function unknown 29375462 Common - oxidoreductase, aldo/keto reductase 2 family EF0877 191 COG4989 COG4989, Predicted oxidoreductase General function prediction only 29377398 Common thiI thiazole biosynthesis protein ThiI EF2934 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 29375532 Common ung uracil-DNA glycosylase EF0948 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 29376016 Pathogen - hypothetical protein EF1449 1 None None None 29375209 Common - gls24 protein EF0604 34 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 29377738 Common - hypothetical protein EF3297 28 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 29376723 Pathogen - hypothetical protein EF2216 2 COG1289 COG1289, Predicted membrane protein Function unknown 29374819 Common - lipase/acylhydrolase EF0169 63 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 29377712 Common folB dihydroneopterin aldolase EF3269 104 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 29375330 Common arcC-3 carbamate kinase EF0735 67 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 29376813 Pathogen - hypothetical protein EF2311 1 None None None 29377380 Common - hydrolase, haloacid dehalogenase-like family EF2916 176 COG0546 Gph, Predicted phosphatases General function prediction only 29375974 Pathogen - hypothetical protein EF1407 2 None None None 29376261 Common - sugar-binding transcriptional regulator, GntR family EF1709 146 COG1609 PurR, Transcriptional regulators Transcription 29377010 Common - hypothetical protein EF2521 6 None None None 29376738 Common - hypothetical protein EF2231 2 None None None 29377395 Common valS valyl-tRNA synthetase EF2931 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375960 Common - molybdopterin cofactor biosynthesis protein A, putative EF1393 202 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 29374934 Common - V-type ATPase, subunit J EF0295 110 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 29376525 Pathogen - hypothetical protein EF2010 1 None None None 29377439 Common - pyridoxal phosphate-dependent enzyme, putative EF2976 48 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 29374735 Common - major facilitator family transporter EF0082 184 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29375548 Common - hypothetical protein EF0965 4 None None None 29376350 Common lacC tagatose-6-phosphate kinase EF1806 105 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 29377697 Common ubiA prenyltransferase EF3254 79 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 29375040 Common - nitroreductase family protein EF0404 93 COG0778 NfnB, Nitroreductase Energy production and conversion 29376645 Pathogen - hypothetical protein EF2136 1 None None None 29377279 Common - hypothetical protein EF2810 2 None None None 29376778 Pathogen - hypothetical protein EF2275 1 None None None 29375435 Pathogen - hypothetical protein EF0847 1 None None None 29377174 Common pfs MTA/SAH nucleosidase EF2694 111 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 29374821 Common adD adenosine deaminase EF0171 112 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 29377369 Common - ABC transporter, permease protein EF2905 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 29377214 Common - thioredoxin reductase/glutathione-related protein EF2738 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 29376822 Common - traE protein, putative EF2320 40 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 29375385 Common - conserved hypothetical protein TIGR01212 EF0795 78 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 29375012 Pathogen - lipoprotein, putative EF0374 2 None None None 29375116 Pathogen - hypothetical protein EF0488 1 None None None 29377087 Common - hypothetical protein EF2602 215 COG0628 PerM, Predicted permease General function prediction only 29376701 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase EF2193 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 29377699 Common - pheromone cAD1 precursor lipoprotein EF3256 10 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 29374789 Common - hypothetical protein EF0138 3 COG2361 COG2361, Uncharacterized conserved protein Function unknown 29375274 Common argR arginine repressor EF0676 74 COG1438 ArgR, Arginine repressor Transcription 29376816 Common - bacteriocin, putative EF2314 2 COG5373 COG5373, Predicted membrane protein Function unknown 29376029 Common - hypothetical protein EF1462 3 None None None 29377386 Common - hypothetical protein EF2922 47 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 29377604 Common mscL large conductance mechanosensitive channel protein EF3152 144 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 29375567 Pathogen - hypothetical protein EF0985 1 None None None 29374988 Common - tail protein, putative EF0349 4 None None None 29376131 Common - prephenate dehydratase EF1568 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 29374902 Pathogen - hypothetical protein EF0261 1 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 29377607 Common - hypothetical protein EF3155 2 None None None 29375403 Common - transcriptional regulator, GntR family EF0814 104 COG2188 PhnF, Transcriptional regulators Transcription 29375146 Common - choloylglycine hydrolase family protein EF0521 28 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 29376769 Common - carbohydrate kinase, pfkB family EF2265 108 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 29377018 Pathogen - hypothetical protein EF2529 1 None None None 29375663 Common - spermine/spermidine acetyltransferase, putative EF1086 18 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 29376660 Common glmS D-fructose-6-phosphate amidotransferase EF2151 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 29376781 Common - lipoprotein, NLP/P60 family EF2278 132 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 29376385 Common - site-specific recombinase, phage integrase family EF1847 101 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29377471 Common - hypothetical protein EF3010 53 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 29377056 Common - hypothetical protein EF2569 77 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 29375185 Common - hypothetical protein EF0573 6 None None None 29376861 Pathogen - hypothetical protein EF2363 1 None None None 29376471 Pathogen - hypothetical protein EF1946 1 None None None 29376086 Common dnaG DNA primase EF1521 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 29377023 Common - hypothetical protein EF2534 10 COG2361 COG2361, Uncharacterized conserved protein Function unknown 29375636 Common - Mn2+/Fe2+ transporter, NRAMP family EF1057 86 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 29377272 Common - hypothetical protein EF2801 6 None None None 29377143 Common - hypothetical protein EF2659 17 COG4708 COG4708, Predicted membrane protein Function unknown 29377487 Common - putative tRNA-binding domain protein EF3028 198 COG0073 ARC1, EMAP domain General function prediction only 29377316 Pathogen - hypothetical protein EF2848 1 None None None 29374812 Pathogen - hypothetical protein EF0162 1 None None None 29375914 Common - glycosyl hydrolase, family 13 EF1347 173 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 29375300 Common - hypothetical protein EF0703 29 COG2323 COG2323, Predicted membrane protein Function unknown 29375537 Common - sugar-binding transcriptional regulator, LacI family EF0954 128 COG1609 PurR, Transcriptional regulators Transcription 29374970 Pathogen - hypothetical protein EF0331 2 None None None 29374919 Common - cation efflux family protein EF0280 66 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 29376431 Common - hypothetical protein EF1903 18 COG0398 COG0398, Uncharacterized conserved protein Function unknown 29376518 Common - tail protein, putative EF2002 6 COG4722 COG4722, Phage-related protein Function unknown 29376051 Common - hypothetical protein EF1484 2 COG2966 COG2966, Uncharacterized conserved protein Function unknown 29377004 Common - hypothetical protein EF2515 7 None None None 29375508 Common - hypothetical protein EF0924 68 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 29375857 Common - hypothetical protein EF1288 14 COG5412 COG5412, Phage-related protein Function unknown 29377546 Common - bifunctional glutamate--cysteine ligase/glutathione synthetase EF3089 96 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 29375467 Common - replication initiation and membrane attachment protein DnaB, putative EF0882 16 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 29375337 Pathogen - hypothetical protein EF0743 1 None None None 29377215 Common ahpC alkyl hydroperoxide reductase, C subunit EF2739 217 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 29375792 Common - spermidine/putrescine ABC transporter, permease protein EF1219 223 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 29375812 Common - hypothetical protein EF1239 35 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 29377345 Common accB acetyl-CoA carboxylase, biotin carboxyl carrier protein EF2879 183 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 29376311 Common secA preprotein translocase subunit SecA EF1763 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 29376422 Common - hypothetical protein EF1894 6 None None None 29375686 Common - YkgG family protein EF1110 43 COG1556 COG1556, Uncharacterized conserved protein Function unknown 29376397 Common - DNA-binding response regulator EF1864 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376681 Common - ISEf1, transposase EF2173 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29376591 Common - ABC transporter, ATP-binding protein EF2082 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 29376290 Common - penicillin-binding protein 1B, putative EF1740 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 29377762 Common citD citrate lyase subunit gamma EF3321 25 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 29377761 Common citE citrate lyase, beta subunit EF3320 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 29375583 Common - S4 domain protein EF1001 33 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 29377049 Common - flavodoxin EF2562 9 COG0716 FldA, Flavodoxins Energy production and conversion 29377412 Common - DNA primase domain protein EF2948 37 COG3378 COG3378, Predicted ATPase General function prediction only 29374715 Common - ABC transporter, permease protein EF0057 191 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 29375973 Common uvrC excinuclease ABC subunit C EF1406 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 29376638 Common - DNA replication protein, putative EF2129 27 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 29377587 Common - hypothetical protein EF3133 35 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 29376513 Common - endolysin EF1992 36 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 29376977 Common - ABC transporter, permease protein EF2485 160 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 29376889 Common - aminotransferase, class V EF2392 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 29376020 Common - hypothetical protein EF1453 3 None None None 29375425 Common - dihydroorotase EF0837 25 COG3964 COG3964, Predicted amidohydrolase General function prediction only 29375226 Pathogen - hypothetical protein EF0624 1 None None None 29374862 Common rplX 50S ribosomal protein L24 EF0217 214 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 29375293 Common lacD-1 tagatose 1,6-diphosphate aldolase EF0696 26 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 29375499 Common rpmI 50S ribosomal protein L35 EF0915 16 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 29376254 Common - hypothetical protein EF1702 76 COG1683 COG1683, Uncharacterized conserved protein Function unknown 29375319 Pathogen - hypothetical protein EF0723 1 None None None 29375413 Common udk uridine kinase EF0825 68 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 29377700 Common - oxidoreductase, pyridine nucleotide-disulfide family EF3257 182 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 29375307 Common ptsI phosphoenolpyruvate-protein phosphotransferase enzyme I EF0710 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 29376404 Common - hypothetical protein EF1875 6 None None None 29374961 Common - hypothetical protein EF0322 13 None None None 29376468 Common - drug resistance transporter, Bcr/CflA family protein EF1943 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29377594 Common - alcohol dehydrogenase, iron-containing EF3140 60 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 29377755 Common - cell wall surface anchor family protein EF3314 46 None None None 29376336 Common - YjeF-related protein EF1790 196 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 29375321 Common gatA glutamyl-tRNA(Gln) amidotransferase, A subunit EF0725 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 29376853 Common lepA GTP-binding protein LepA EF2352 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 29375510 Common - DNA-binding response regulator EF0926 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376461 Pathogen - hypothetical protein EF1935 1 None None None 29376112 Common engA GTP-binding protein EngA EF1549 221 COG1160 COG1160, Predicted GTPases General function prediction only 29375519 Common - primase-related protein EF0935 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 29375267 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase EF0668 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 29376078 Common - mandelate racemase/muconate lactonizing enzyme family protein EF1511 139 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 29375856 Common - hypothetical protein EF1287 4 None None None 29375849 Common - DNA replication protein, putative EF1280 43 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 29375043 Common - transcriptional regulator, putative EF0407 25 COG3711 BglG, Transcriptional antiterminator Transcription 29375883 Pathogen - hypothetical protein EF1315 1 None None None 29377303 Common - hypothetical protein EF2835 3 None None None 29375578 Common ftsA cell division protein FtsA EF0996 185 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 29375571 Common mraW S-adenosyl-methyltransferase MraW EF0989 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 29376244 Common - oxidoreductase, short-chain dehydrogenase/reductase family EF1690 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 29374756 Common argF-1 ornithine carbamoyltransferase EF0105 232 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 29375102 Common nrdE ribonucleotide-diphosphate reductase subunit alpha EF0471 217 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 29376316 Common - PTS system, IIB component, putative EF1769 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 29375457 Common - cation-transporting ATPase, E1-E2 family EF0871 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 29375011 Common - sensor histidine kinase EF0373 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 29376502 Pathogen - hypothetical protein EF1980 1 None None None 29375631 Pathogen - hypothetical protein EF1052 1 None None None 29377178 Common - tellurite resistance protein, putative EF2698 43 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 29376848 Common - cell wall surface anchor family protein EF2347 11 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29377276 Pathogen - hypothetical protein EF2805 1 None None None 29374670 Common rpsR 30S ribosomal protein S18 EF0009 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 29376202 Common - site-specific recombinase, phage integrase family EF1648 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29377532 Pathogen - hypothetical protein EF3074 1 None None None 29376355 Common gspA-2 general stress protein A EF1811 37 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 29376505 Common ackA acetate kinase EF1983 161 COG0282 ackA, Acetate kinase Energy production and conversion 29375244 Pathogen - hypothetical protein EF0643 1 None None None 29375109 Common - site-specific recombinase, phage integrase family EF0479 168 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29376108 Common recQ-1 ATP-dependent DNA helicase RecQ EF1545 237 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 29376068 Pathogen - hypothetical protein EF1501 1 None None None 29376902 Common glyQ glycyl-tRNA synthetase subunit alpha EF2407 168 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 29374881 Common - ABC transporter, ATP-binding protein EF0237 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 29375616 Common - aspartate aminotransferase EF1037 100 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 29377618 Common - hypothetical protein EF3168 8 COG4550 COG4550, Predicted membrane protein Function unknown 29377048 Common - ferredoxin--NADP(+) reductase subunit alpha EF2561 85 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 29377337 Common nadD nicotinic acid mononucleotide adenyltransferase EF2871 188 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 29377193 Pathogen - cell wall surface anchor family protein EF2713 1 None None None 29376841 Common - C-5 cytosine-specific DNA methylase EF2340 123 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 29375448 Common - hypothetical protein EF0860 63 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 29376598 Pathogen - hypothetical protein EF2089 1 None None None 29376704 Common - glycosyl transferase, group 2 family protein EF2196 5 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 29375733 Common - peptidase, M20/M25/M40 family EF1157 142 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 29377669 Pathogen - hypothetical protein EF3222 1 None None None 29377099 Common atpB F0F1 ATP synthase subunit A EF2614 207 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 29377002 Pathogen - lipoprotein, putative EF2513 1 None None None 29377705 Common - transcriptional regulator, PemK family EF3262 23 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 29377371 Common - ABC transporter, ATP-binding protein EF2907 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 29376803 Common - streptomycin resistance protein, putative EF2300 5 None None None 29377093 Common atpD F0F1 ATP synthase subunit beta EF2608 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 29377420 Common - oxidoreductase, short-chain dehydrogenase/reductase family EF2956 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 29374929 Common metC cystathionine gamma-synthase/cystathionine beta-lyase EF0290 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 29375907 Pathogen - pheromone cAM373 precursor lipoprotein EF1340 1 None None None 29376454 Common glpF glycerol uptake facilitator protein EF1927 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 29377106 Common - hypothetical protein EF2621 36 COG2388 COG2388, Predicted acetyltransferase General function prediction only 29376608 Pathogen - hypothetical protein EF2099 1 None None None 29376061 Common - V-type ATP synthase subunit K EF1494 24 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 29374963 Pathogen - hypothetical protein EF0324 1 None None None 29375928 Common - dihydroxyacetone kinase family protein EF1361 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 29377185 Common recX recombination regulator RecX EF2705 38 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 29374908 Common - zinc-binding TIM-barrel protein, nifR3 family, putative EF0267 214 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 29377448 Common - permease, putative EF2985 157 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 29376713 Common - cytidine/deoxycytidylate deaminase family protein EF2206 218 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 29375600 Common - glycosyl hydrolase, family 1 EF1020 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 29375111 Pathogen - hypothetical protein EF0481 4 None None None 29375352 Common - sapB protein, putative EF0759 116 COG1285 SapB, Uncharacterized membrane protein Function unknown 29375153 Common - transcriptional regulator, AraC family EF0530 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 29377534 Pathogen - cell wall surface anchor family protein EF3076 1 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29375473 Common - hypothetical protein EF0888 6 None None None 29376657 Common - hypothetical protein EF2148 4 None None None 29376496 Common relA GTP pyrophosphokinase EF1974 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 29376823 Common - hypothetical protein EF2321 4 None None None 29375461 Pathogen - hypothetical protein EF0876 1 COG3711 BglG, Transcriptional antiterminator Transcription 29375281 Common - cmp-binding protein, putative EF0684 48 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 29375711 Common - hypothetical protein EF1135 123 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 29377092 Common atpC F0F1 ATP synthase subunit epsilon EF2607 154 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 29375177 Pathogen - hypothetical protein EF0563 1 None None None 29374913 Common - phosphoglycerate mutase family protein EF0273 105 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 29375771 Common - hypothetical protein EF1196 7 COG4853 COG4853, Uncharacterized protein conserved in bacteria Function unknown 29376341 Common - lipoprotein, putative EF1796 2 None None None 29376670 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase EF2162 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 29375585 Common ileS isoleucyl-tRNA synthetase EF1003 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376241 Common apt adenine phosphoribosyltransferase EF1687 178 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 29374679 Common - PTS system, mannose-specific IIAB components EF0020 91 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29377328 Common - ErfK/YbiS/YcfS/YnhG family protein, putative EF2860 5 None None None 29377223 Common dtlB basic membrane protein DtlB EF2748 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 29375781 Common - citrate carrier protein, CCS family EF1207 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 29376983 Common - glycosyl transferase, group 2 family protein EF2491 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29377053 Common - hypothetical protein EF2566 25 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 29375394 Common - amino acid ABC transporter, ATP-binding protein EF0805 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 29376698 Common - glycosyl transferase, group 2 family protein EF2190 171 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 29377410 Pathogen - hypothetical protein EF2946 1 None None None 29377165 Common - hypothetical protein EF2684 7 None None None 29374901 Pathogen - hypothetical protein EF0260 1 None None None 29375160 Common - hypothetical protein EF0542 29 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 29374768 Common - transcriptional regulator, GntR family EF0117 176 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 29376865 Common - N-acetylmuramoyl-L-alanine amidase, family 4 EF2367 68 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 29375254 Common - nitroreductase family protein, putative EF0655 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 29374748 Common - regulatory protein pfoR, putative EF0097 9 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 29376667 Common glnA glutamine synthetase, type I EF2159 231 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 29375922 Common aceF dihydrolipoamide acetyltransferase EF1355 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 29377031 Pathogen - hypothetical protein EF2542 1 None None None 29376905 Common era GTP-binding protein Era EF2410 228 COG1159 Era, GTPase General function prediction only 29375948 Common - conserved hypothetical protein TIGR00486 EF1381 93 COG0327 COG0327, Uncharacterized conserved protein Function unknown 29376944 Common - PDZ domain protein EF2450 46 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 29374775 Pathogen - hypothetical protein EF0124 1 None None None 29375651 Common - hypothetical protein EF1073 12 COG0645 COG0645, Predicted kinase General function prediction only 29376161 Common - PTS system, IIABC components EF1601 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29374944 Common - hypothetical protein EF0305 2 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 29376212 Common bkdC branched-chain alpha-keto acid, E2 component, dihydrolipoamide acetyltransferase EF1658 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 29377518 Common - secreted lipase, putative EF3060 12 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 29375650 Common galR galactose operon repressor galR EF1072 123 COG1609 PurR, Transcriptional regulators Transcription 29375980 Common - msrC protein, putative EF1413 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 29377026 Pathogen - hypothetical protein EF2537 1 None None None 29377647 Common - ABC transporter, permease protein EF3199 102 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 29375308 Common - hypothetical protein EF0711 8 None None None 29377589 Common - mannonate dehydratase EF3135 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 29376175 Common - CoA-binding domain protein EF1616 121 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 29375805 Common - ABC transporter, permease protein EF1232 150 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 29376922 Common - transcriptional regulator, PadR family EF2428 41 COG1695 COG1695, Predicted transcriptional regulators Transcription 29375083 Common - AMP-binding family protein EF0452 131 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 29374920 Pathogen - hypothetical protein EF0281 1 None None None 29376650 Common - transcriptional regulator, Cro/CI family EF2141 9 COG1476 COG1476, Predicted transcriptional regulators Transcription 29377293 Pathogen - hypothetical protein EF2824 2 None None None 29377253 Common dnaX DNA polymerase III, gamma and tau subunits EF2781 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 29376561 Common - ABC transporter, ATP-binding protein EF2050 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 29377573 Common - thiamin pyrophosphokinase family protein EF3117 39 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 29376770 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase EF2266 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 29376328 Common purF amidophosphoribosyltransferase EF1781 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 29375203 Pathogen - hypothetical protein EF0594 1 None None None 29377088 Common - PTS system, IIA component EF2603 9 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 29377121 Common - abortive infection protein EF2637 13 None None None 29374989 Common - hypothetical protein EF0350 4 None None None 29376910 Common - hypothetical protein EF2415 150 COG1610 COG1610, Uncharacterized conserved protein Function unknown 29376159 Common phrB deoxyribodipyrimidine photolyase EF1598 134 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 29376207 Common rnhB ribonuclease HII EF1653 228 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 29375524 Common - hypothetical protein EF0940 9 None None None 29375626 Common - hypothetical protein EF1047 14 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 29374698 Common radA DNA repair protein RadA EF0040 202 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 29377408 Pathogen - hypothetical protein EF2944 1 None None None 29377659 Common - PTS system, IIB component EF3211 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29375989 Common - transcriptional regulator, Cro/CI family EF1422 34 COG1476 COG1476, Predicted transcriptional regulators Transcription 29375642 Common - hypothetical protein EF1063 80 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 29374868 Common rpsE ribosomal protein S5 EF0224 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 29375657 Common - ImpB/MucB/SamB family protein EF1080 177 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 29375892 Pathogen - hypothetical protein EF1325 1 None None None 29374776 Common - IS256, transposase EF0125 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29377717 Common - hypothetical protein EF3274 2 None None None 29374684 Pathogen - hypothetical protein EF0026 1 None None None 29376005 Pathogen - hypothetical protein EF1438 1 None None None 29374953 Pathogen - hypothetical protein EF0314 1 None None None 29375294 Common - hypothetical protein EF0697 16 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 29376095 Common - transcriptional regulator, TetR family EF1531 11 COG1309 AcrR, Transcriptional regulator Transcription 29377230 Common dinP DNA-damage-inducible protein P EF2756 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 29376557 Common comG1 competence protein EF2046 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 29375927 Common - dihydroxyacetone kinase family protein EF1360 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 29375181 Common kdpB potassium-transporting ATPase subunit B EF0568 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 29377378 Common greA transcription elongation factor GreA EF2914 201 COG0782 GreA, Transcription elongation factor Transcription 29375747 Common rpmE ribosomal protein L31 EF1171 160 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 29375055 Common - transcriptional regulator, IclR family EF0422 120 COG1414 IclR, Transcriptional regulator Transcription 29376282 Common - ABC transporter, ATP-binding/permease protein, MDR family EF1732 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29377239 Pathogen - hypothetical protein EF2765 1 None None None 29376271 Common pyrB aspartate carbamoyltransferase catalytic subunit EF1719 239 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 29376834 Pathogen - hypothetical protein EF2333 1 None None None 29375762 Common - hypothetical protein EF1187 11 COG4470 COG4470, Uncharacterized protein conserved in bacteria Function unknown 29375155 Pathogen - hypothetical protein EF0532 1 None None None 29375595 Pathogen - hypothetical protein EF1015 1 None None None 29377195 Common rplJ 50S ribosomal protein L10 EF2716 216 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 29376151 Common - protease synthase and sporulation negative regulatory protein pai 1, putative EF1590 25 COG0456 RimI, Acetyltransferases General function prediction only 29376184 Common - microcompartment protein family EF1625 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 29377650 Common rpsN 30S ribosomal protein S14 EF3202 203 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 29376344 Common - hypothetical protein EF1800 8 None None None 29376796 Common vanX D-alanyl-D-alanine dipeptidase EF2293 55 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 29374941 Common pepC aminopeptidase C EF0302 16 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 29374842 Common - site-specific recombinase, resolvase family EF0196 102 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 29377453 Common - rhodanese family protein EF2990 120 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 29377365 Common - D-isomer specific 2-hydroxyacid dehydrogenase family protein EF2901 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 29377510 Pathogen - hypothetical protein EF3052 1 None None None 29376193 Common - propanediol utilization protein PduV EF1638 19 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 29374954 Common - hypothetical protein EF0315 2 None None None 29377578 Common sun Sun protein EF3122 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 29377640 Common - lipase, putative EF3191 112 COG0657 Aes, Esterase/lipase Lipid metabolism 29376181 Pathogen - hypothetical protein EF1622 1 None None None 29375582 Common - hypothetical protein EF1000 13 COG0762 COG0762, Predicted integral membrane protein Function unknown 29375756 Common - nitroreductase family protein EF1181 75 COG0778 NfnB, Nitroreductase Energy production and conversion 29375454 Common - glyoxalase family protein EF0867 36 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 29376585 Common - endocarditis specific antigen EF2076 171 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 29377247 Common - hypothetical protein EF2774 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 29376300 Common - hypothetical protein EF1751 71 COG1950 COG1950, Predicted membrane protein Function unknown 29376783 Common - hypothetical protein EF2280 14 COG0433 COG0433, Predicted ATPase General function prediction only 29376460 Common - hypothetical protein EF1934 3 None None None 29376224 Common - phospholipase/carboxylesterase family protein EF1670 43 COG0400 COG0400, Predicted esterase General function prediction only 29374667 Common gyrA DNA gyrase, A subunit EF0006 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 29376406 Common - hypothetical protein EF1877 7 None None None 29376974 Common - hydrolase, haloacid dehalogenase-like family EF2481 34 COG0546 Gph, Predicted phosphatases General function prediction only 29374716 Common purR purine operon repressor EF0058 138 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 29375560 Common folD methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase EF0978 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 29375296 Common - hypothetical protein EF0699 165 COG0628 PerM, Predicted permease General function prediction only 29374745 Common - formate/nitrite transporter family protein EF0094 101 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 29374696 Common proB gamma-glutamyl kinase EF0038 191 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 29375790 Pathogen - lipoprotein, putative EF1217 1 None None None 29374865 Common rpsH 30S ribosomal protein S8 EF0220 249 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 29375432 Pathogen - hypothetical protein EF0844 1 None None None 29376540 Pathogen - hypothetical protein EF2025 1 None None None 29377580 Common priA primosomal protein n' EF3125 216 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 29377208 Common rpmG-2 ribosomal protein L33 EF2731 34 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 29375038 Common nhaC-1 Na+/H+ antiporter EF0402 62 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 29376018 Pathogen - hypothetical protein EF1451 1 None None None 29375879 Common - hypothetical protein EF1311 70 None None None 29376330 Common purQ phosphoribosylformylglycinamidine synthetase I EF1783 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 29374710 Pathogen - hypothetical protein EF0052 1 None None None 29376252 Common ffh signal recognition particle protein EF1700 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 29375971 Common - MutS2 family protein EF1404 201 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 29375913 Pathogen - hypothetical protein EF1346 1 None None None 29376748 Common - hypothetical protein EF2241 5 None None None 29376634 Pathogen - hypothetical protein EF2125 1 None None None 29377764 Pathogen - hypothetical protein EF3323 1 None None None 29375034 Pathogen - hypothetical protein EF0398 1 None None None 29375422 Common - PTS system, IIC component EF0834 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29376022 Common - terminase, large subunit, putative EF1455 31 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 29376519 Common - tape measure protein, putative EF2003 53 COG5412 COG5412, Phage-related protein Function unknown 29376337 Common - pheromone binding protein EF1791 180 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 29376448 Common - C4-dicarboxylate anaerobic carrier EF1920 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 29376959 Pathogen - hypothetical protein EF2465 1 None None None 29377756 Common - triphosphoribosyl-dephospho-CoA synthase EF3315 45 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 29375539 Common pgmB beta-phosphoglucomutase EF0956 173 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 29375804 Common - hypothetical protein EF1231 107 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 29375863 Common ribF riboflavin biosynthesis protein RibF EF1295 211 COG0196 RibF, FAD synthase Coenzyme metabolism 29375096 Common - transcriptional regulator EF0465 61 COG1316 LytR, Transcriptional regulator Transcription 29375187 Common - cationic ABC transporter, ATP-binding protein EF0575 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 29376839 Common - transcriptional regulator, Cro/CI family EF2338 8 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 29377245 Common - hypothetical protein EF2771 9 None None None 29376124 Common aroE shikimate 5-dehydrogenase EF1561 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 29375998 Pathogen - hypothetical protein EF1431 1 None None None 29376076 Common - hypothetical protein EF1509 8 None None None 29376259 Common - glycosyl hydrolase, family 38 EF1707 46 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 29375758 Common asd aspartate-semialdehyde dehydrogenase EF1183 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 29374795 Pathogen - hypothetical protein EF0144 1 None None None 29375407 Common - polysaccharide lyase, family 8 EF0818 13 None None None 29376790 Pathogen - hypothetical protein EF2287 1 None None None 29377015 Pathogen - hypothetical protein EF2526 1 None None None 29375311 Common tig trigger factor EF0715 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 29376679 Common - epimerase/dehydratase, putative EF2171 216 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 29375217 Pathogen - hypothetical protein EF0612 1 None None None 29375942 Pathogen - hypothetical protein EF1375 1 None None None 29377068 Common - oxidoreductase, pyridine nucleotide-disulfide family EF2581 198 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 29374808 Common - conjugal transfer protein, putative EF0158 13 COG0433 COG0433, Predicted ATPase General function prediction only 29375210 Common - hypothetical protein EF0605 4 None None None 29377555 Pathogen - transporter accessory protein, putative EF3099 1 None None None 29374672 Common rplI 50S ribosomal protein L9 EF0012 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 29375728 Common - hypothetical protein EF1152 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 29377605 Common - hypothetical protein EF3153 4 None None None 29376302 Common - hypothetical protein EF1753 13 COG3595 COG3595, Uncharacterized conserved protein Function unknown 29375725 Common recU Holliday junction-specific endonuclease EF1149 17 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 29376623 Common - adenine methyltransferase, putative EF2114 90 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 29377743 Pathogen - hypothetical protein EF3302 1 None None None 29375784 Common npr NADH peroxidase EF1211 229 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 29375419 Common - hypothetical protein EF0831 11 None None None 29377649 Common - OsmC/Ohr family protein EF3201 4 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 29376054 Pathogen - hypothetical protein EF1487 1 None None None 29374737 Pathogen - hypothetical protein EF0084 1 None None None 29375192 Common - hypothetical protein EF0580 30 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 29377447 Pathogen - transcriptional regulator, putative EF2984 1 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376894 Common tsf elongation factor Ts EF2397 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 29376687 Common - hypothetical protein EF2179 3 None None None 29375815 Common - transcriptional regulator, GntR family EF1242 114 COG2188 PhnF, Transcriptional regulators Transcription 29375661 Common - universal stress protein family EF1084 119 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 29377473 Common - hypothetical protein EF3012 3 None None None 29376484 Common tpiA triosephosphate isomerase EF1962 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 29375569 Common - lipoprotein, putative EF0987 5 None None None 29377568 Common plsX fatty acid/phospholipid synthesis protein EF3112 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 29376493 Common hisS histidyl-tRNA synthetase EF1971 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376426 Common rplS 50S ribosomal protein L19 EF1898 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 29377393 Common - hypothetical protein EF2929 8 COG4485 COG4485, Predicted membrane protein Function unknown 29375196 Common - ABC transporter, ATP-binding/permease protein EF0584 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29376088 Common - conserved domainl protein EF1523 3 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 29375416 Common - hypothetical protein EF0828 30 COG3711 BglG, Transcriptional antiterminator Transcription 29375660 Pathogen - hypothetical protein EF1083 1 None None None 29375677 Common - hypothetical protein EF1101 7 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 29375316 Common - voltage-gated chloride channel family protein EF0720 155 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 29376325 Common purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase EF1778 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 29376526 Common - hypothetical protein EF2011 6 None None None 29376757 Pathogen - hypothetical protein EF2252 1 None None None 29374814 Pathogen - lipoprotein, putative EF0164 1 None None None 29374829 Common - ABC transporter, permease protein EF0179 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 29375205 Pathogen - hypothetical protein EF0599 1 None None None 29377212 Common exoA exodeoxyribonuclease EF2735 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 29375340 Common - penicillin-binding protein, putative EF0746 104 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 29374932 Common - phosphosugar-binding transcriptional regulator, putative EF0293 96 COG1737 RpiR, Transcriptional regulators Transcription 29375958 Common - molybdenum cofactor biosynthesis family protein EF1391 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 29374891 Common - NAD-dependent deacetylase EF0249 149 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 29376740 Common - ABC transporter, permease protein EF2233 168 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 29376043 Common - hypothetical protein EF1476 8 None None None 29375966 Common - molybdenum ABC transporter, ATP-binding protein, putative EF1399 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 29377710 Common folE GTP cyclohydrolase I EF3267 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 29375260 Common - oligoendopeptidase F, putative EF0661 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 29377684 Common birA BirA bifunctional protein EF3240 187 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 29376395 Common - hypothetical protein EF1861 52 COG5495 COG5495, Uncharacterized conserved protein Function unknown 29377038 Common upp uracil phosphoribosyltransferase EF2549 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 29375332 Pathogen - hypothetical protein EF0738 1 None None None 29377333 Common - hypothetical protein EF2866 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 29375354 Common - amino acid ABC transporter, amino acid-binding/permease protein EF0761 198 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 29377343 Common accC acetyl-CoA carboxylase biotin carboxylase subunit EF2877 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 29375376 Common - drug resistance transporter, EmrB/QacA family protein EF0785 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29375477 Common - amino acid ABC transporter, ATP-binding protein EF0892 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 29375819 Common - hypothetical protein EF1247 3 None None None 29376093 Pathogen - hypothetical protein EF1528 1 None None None 29375224 Pathogen - hypothetical protein EF0621 1 None None None 29377315 Common - hypothetical protein EF2847 7 None None None 29375387 Common - hypothetical protein EF0797 10 None None None 29375968 Pathogen - hypothetical protein EF1401 1 None None None 29376907 Common - hypothetical protein EF2412 203 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 29376478 Common - PTS system, IIC component EF1953 37 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29376938 Common - acyl-CoA thioester hydrolase EF2444 98 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 29376263 Common - carbonic anhydrase, putative EF1711 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 29377464 Pathogen - lipoprotein, putative EF3003 1 None None None 29376735 Common - tryptophanyl-tRNA synthetase II EF2228 248 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29375541 Common - PTS system, IIABC components EF0958 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29376776 Common - glucuronyl hydrolase, putative EF2272 20 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 29377592 Common - PTS system, IID component EF3138 36 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29376114 Pathogen - hypothetical protein EF1551 1 None None None 29377278 Pathogen - hypothetical protein EF2807 1 None None None 29377286 Pathogen - hypothetical protein EF2817 2 COG1609 PurR, Transcriptional regulators Transcription 29374848 Common - phosphomethylpyrimidine kinase, putative EF0202 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 29376367 Common - glycosyl hydrolase, family 31/fibronectin type III domain protein EF1824 86 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 29374820 Common - hypothetical protein EF0170 83 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 29375027 Common - N-acyl-D-amino-acid deacylase family protein EF0390 88 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 29375148 Common - transcriptional regulator, Cro/CI family EF0524 67 COG1476 COG1476, Predicted transcriptional regulators Transcription 29376965 Common gcp O-sialoglycoprotein endopeptidase EF2472 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 29376818 Common - hypothetical protein EF2316 7 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 29376915 Common thrC threonine synthase EF2421 156 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 29375002 Common - ISEf1, transposase EF0363 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 29376799 Common vanW vancomycin B-type resistance protein VanW EF2296 35 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 29377390 Common radC DNA repair protein RadC EF2926 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 29376048 Common - hypothetical protein EF1481 7 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 29375347 Common - hypothetical protein EF0754 7 None None None 29376952 Common - hypothetical protein EF2458 7 COG4838 COG4838, Uncharacterized protein conserved in bacteria Function unknown 29375400 Common - hypothetical protein EF0811 4 None None None 29376996 Common - hypothetical protein EF2504 4 None None None 29374681 Common - PTS system, mannose-specific IID component EF0022 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 29377726 Common ctsR transcriptional regulator CtsR EF3283 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 29376931 Common - hypothetical protein EF2437 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 29376239 Common hlyIII hemolysin III EF1685 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 29375265 Common - glyoxalase family protein EF0666 36 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 29377707 Pathogen - hypothetical protein EF3264 1 None None None 29376473 Common - hypothetical protein EF1948 16 COG5646 COG5646, Uncharacterized conserved protein Function unknown 29375501 Common - hypothetical protein EF0917 13 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 29375550 Common - hypothetical protein EF0967 72 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 29377419 Common - site-specific recombinase, phage integrase family EF2955 140 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29376636 Pathogen - hypothetical protein EF2127 1 None None None 29377730 Pathogen - hypothetical protein EF3287 1 None None None 29375845 Common - hypothetical protein EF1276 7 None None None 29375559 Common nusB transcription antitermination protein NusB EF0977 183 COG0781 NusB, Transcription termination factor Transcription 29375365 Common - hypothetical protein EF0773 2 None None None 29376755 Common - hypothetical protein EF2250 33 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 29375446 Common pip phage infection protein EF0858 33 COG1511 COG1511, Predicted membrane protein Function unknown 29375613 Common - hypothetical protein EF1034 13 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 29375795 Common ade adenine deaminase EF1222 72 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 29377220 Common - peptidase, M42 family EF2744 82 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 29377267 Pathogen - LysM domain lipoprotein EF2795 1 None None None 29376231 Pathogen - lipoprotein, putative EF1677 1 None None None 29377352 Common - transcriptional regulator, MarR family EF2886 20 COG1846 MarR, Transcriptional regulators Transcription 29374724 Pathogen - hypothetical protein EF0068 1 None None None 29375009 Common - aminotransferase, class V EF0371 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 29376729 Common - ABC transporter, permease protein EF2222 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 29375126 Pathogen - hypothetical protein EF0498 1 None None None 29376576 Common - conserved hypothetical protein TIGR00481 EF2067 14 COG1881 COG1881, Phospholipid-binding protein General function prediction only 29375706 Common - putative L-xylulose 5-phosphate 3-epimerase EF1130 26 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 29375062 Common - TRAP dicarboxylate transporter, DctQ subunit EF0430 69 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 29375951 Common - hypothetical protein EF1384 11 COG0392 COG0392, Predicted integral membrane protein Function unknown 29376732 Common - transcriptional regulator, MerR family EF2225 35 COG0789 SoxR, Predicted transcriptional regulators Transcription 29376644 Pathogen - hypothetical protein EF2135 1 None None None 29377694 Pathogen - hypothetical protein EF3251 1 None None None 29377481 Common - hypothetical protein EF3021 13 None None None 29376144 Common - major facilitator family transporter EF1582 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 29375517 Common - hypothetical protein EF0933 32 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 29376295 Common galU UTP-glucose-1-phosphate uridylyltransferase EF1746 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 29376854 Common - acetyltransferase, GNAT family EF2353 23 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 29375934 Common - cold-shock domain family protein EF1367 184 COG1278 CspC, Cold shock proteins Transcription 29374851 Common rplC 50S ribosomal protein L3 EF0206 249 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 29376863 Common xpt xanthine phosphoribosyltransferase EF2365 117 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 29376071 Common lysA diaminopimelate decarboxylase EF1504 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 29375905 Common trxB thioredoxin reductase EF1338 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 29377376 Common - sensor histidine kinase, putative EF2912 158 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 29377104 Pathogen - hypothetical protein EF2619 1 None None None 29374778 Common - hypothetical protein EF0127 2 None None None 29375674 Common - hypothetical protein EF1098 8 COG4269 COG4269, Predicted membrane protein Function unknown 29375829 Common - DNA-binding response regulator EF1260 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 29376417 Pathogen - hypothetical protein EF1888 2 None None None 29377071 Pathogen - hypothetical protein EF2584 1 None None None 29377363 Common - oxidoreductase, pyridine nucleotide-disulfide family EF2899 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 29374706 Common - hypothetical protein EF0048 29 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 29375048 Common mtlD mannitol-1-phosphate 5-dehydrogenase EF0413 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 29376988 Common - pheromone cOB1 precursor/lipoprotein, YaeC family EF2496 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 29377504 Common - PTS system, IIA component EF3046 79 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29375529 Common - acetyltransferase, GNAT family EF0945 32 COG0456 RimI, Acetyltransferases General function prediction only 29376765 Pathogen - hypothetical protein EF2261 1 None None None 29374974 Common - minor head protein EF0335 9 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 29375713 Pathogen - hypothetical protein EF1137 1 None None None 29374705 Common - RNA methyltransferase, TrmH family EF0047 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 29375201 Common - hypothetical protein EF0589 100 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 29377191 Common - transcriptional regulator, AraC family EF2711 33 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 29376371 Common - glycerol uptake facilitator protein, putative EF1828 122 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 29377221 Common dltD dltD protein EF2746 13 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 29375870 Common - transcriptional regulator, putative EF1302 166 COG0583 LysR, Transcriptional regulator Transcription 29376494 Pathogen - hypothetical protein EF1972 1 None None None 29376052 Pathogen - hypothetical protein EF1485 1 None None None 29377273 Common - endolysin EF2802 42 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 29375837 Common - cation-transporting ATPase, E1-E2 family EF1268 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 29376378 Common - PTS system, IIB component, putative EF1837 4 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 29376730 Common - ABC transporter, permease protein EF2223 137 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 29376593 Common - hypothetical protein EF2084 2 None None None 29377063 Pathogen - hypothetical protein EF2576 1 None None None 29376715 Common - phenazine biosynthesis protein PhzF family EF2208 112 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 29377465 Common - sulfate transporter family/STAS domain protein EF3004 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 29374677 Common - sigma-54 interaction domain protein EF0018 155 COG3933 COG3933, Transcriptional antiterminator Transcription 29376665 Common - conserved hypothetical protein TIGR00159 EF2157 69 COG1624 COG1624, Uncharacterized conserved protein Function unknown 29375288 Common trmB tRNA (guanine-N(7))-methyltransferase EF0691 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 29376981 Common - MurB family protein EF2489 160 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 29377108 Common cadA cadmium-translocating P-type ATPase EF2623 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 29377475 Common - cation-transporting ATPase, E1-E2 family EF3014 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 29375363 Common - hypothetical protein EF0770 6 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 29377431 Pathogen - hypothetical protein EF2967 1 None None None 29375820 Pathogen - hypothetical protein EF1248 1 None None None 29374840 Common - NADH-dependent butanol dehydrogenase, putative EF0194 171 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 29376612 Pathogen - hypothetical protein EF2103 1 None None None 29375392 Common - hypothetical protein EF0803 8 None None None 29374746 Common - lipoprotein, putative EF0095 5 None None None 29377496 Common pepA glutamyl-aminopeptidase EF3037 88 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 29375162 Common rpmF 50S ribosomal protein L32 EF0544 5 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 29376587 Pathogen - hypothetical protein EF2078 1 None None None 29375360 Common - hypothetical protein EF0767 96 COG0391 COG0391, Uncharacterized conserved protein Function unknown 29376893 Common pyrH uridylate kinase EF2396 243 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 29375788 Pathogen - hypothetical protein EF1215 1 None None None 29375039 Common - transcriptional regulator, MarR family EF0403 60 COG1846 MarR, Transcriptional regulators Transcription 29374983 Common - hypothetical protein EF0344 2 None None None 29375699 Common - hypothetical protein EF1123 42 COG0622 COG0622, Predicted phosphoesterase General function prediction only 29375903 Common - response regulator EF1336 141 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 29375694 Common - amino acid ABC transporter, permease protein EF1118 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 29377167 Common - hypothetical protein EF2687 2 None None None 29377111 Common - nicotinate phosphoribosyltransferase EF2626 119 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 29377443 Common - PTS system, IIA component EF2980 43 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 29377171 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative EF2691 77 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 29377634 Common - hypothetical protein EF3184 7 None None None 29374946 Common - transcriptional regulator, Cro/CI family EF0307 8 COG1476 COG1476, Predicted transcriptional regulators Transcription 29375041 Common - hydrolase, haloacid dehalogenase-like family EF0405 123 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 29376204 Common topA DNA topoisomerase I EF1650 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 29377678 Pathogen - lipoprotein, putative EF3234 1 None None None 29375133 Pathogen - hypothetical protein EF0505 1 None None None 29376314 Common comFA competence protein F EF1767 92 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 29375885 Common nagA-1 N-acetylglucosamine-6-phosphate deacetylase EF1317 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 29377251 Common - hypothetical protein EF2778 12 COG4732 COG4732, Predicted membrane protein Function unknown 29374994 Common - endolysin, putative EF0355 10 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 29377451 Common - rhodanese family protein EF2988 144 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 29377491 Common - hypothetical protein EF3032 26 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 29376535 Pathogen - hypothetical protein EF2020 1 None None None 29376881 Pathogen - hypothetical protein EF2384 1 None None None 29375847 Pathogen - hypothetical protein EF1278 1 None None None 29376619 Pathogen - hypothetical protein EF2110 1 None None None 29376846 Common - hypothetical protein EF2345 6 None None None 29375986 Pathogen - hypothetical protein EF1419 1 None None None 29375799 Common - oxidoreductase, putative EF1226 109 COG0431 COG0431, Predicted flavoprotein General function prediction only 29376500 Common - DNA-3-methyladenine glycosylase EF1978 82 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 29375013 Pathogen - hypothetical protein EF0375 2 None None None 29377077 Common - hypothetical protein EF2590 123 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 29375480 Common tgt queuine tRNA-ribosyltransferase EF0896 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 29377289 Common - major capsid protein EF2820 23 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 29376946 Common - methylase, putative EF2452 214 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 29375490 Common - hypothetical protein EF0906 20 COG1289 COG1289, Predicted membrane protein Function unknown 29376825 Common - hypothetical protein EF2324 4 None None None 29376288 Common - hypothetical protein EF1738 5 COG4430 COG4430, Uncharacterized protein conserved in bacteria Function unknown 29375212 Common - ParB-like nuclease domain protein EF0607 19 COG1475 Spo0J, Predicted transcriptional regulators Transcription 29375222 Common - hypothetical protein EF0618 24 COG1378 COG1378, Predicted transcriptional regulators Transcription 29375485 Common - isopentenyl pyrophosphate isomerase EF0901 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 29376353 Common - transcriptional regulator, GntR family EF1809 127 COG2188 PhnF, Transcriptional regulators Transcription 29374999 Common sugE-2 sugE protein EF0360 31 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 29375325 Common - hypothetical protein EF0730 16 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 29377470 Pathogen - hypothetical protein EF3009 1 None None None 29375955 Common - NAD-dependent formate dehydrogenase, gamma subunit, putative EF1388 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 29377374 Common - potassium uptake protein EF2910 132 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 29375242 Common ldh-2 L-lactate dehydrogenase EF0641 167 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 29377417 Pathogen - hypothetical protein EF2953 1 None None None 29375736 Common - PTS system, cellobiose-specific IIC component EF1160 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 29374818 Common - pantothenate kinase EF0168 73 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 29376032 Common - hypothetical protein EF1465 3 None None None 29375513 Common - amino acid permease family protein EF0929 123 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 29376677 Common - hypothetical protein EF2169 8 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 29375618 Common - hydrolase, haloacid dehalogenase-like family EF1039 124 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 29375628 Common gnd 6-phosphogluconate dehydrogenase EF1049 184 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 29375633 Common - ABC transporter, permease protein EF1054 56 COG4986 COG4986, ABC-type anion transport system, duplicated permease component Inorganic ion transport and metabolism 29376221 Common - short chain dehydrogenase family protein EF1667 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29377459 Common - allantoate amidohydrolase EF2997 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 29374888 Common - amino acid ABC transporter, ATP-binding protein EF0246 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 29375977 Common - sugar-binding transcriptional regulator, LacI family EF1410 126 COG1609 PurR, Transcriptional regulators Transcription 29377305 Pathogen - hypothetical protein EF2837 1 None None None 29375269 Common - dipeptidase PepV EF0671 191 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 29376805 Common - hypothetical protein EF2303 10 None None None 29375860 Common - hypothetical protein EF1291 5 None None None 29375740 Common - HD domain protein EF1164 8 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 29376105 Common - hypothetical protein EF1542 9 COG4640 COG4640, Predicted membrane protein Function unknown 29377232 Common - ABC transporter, ATP-binding protein EF2758 249 COG4619 COG4619, ABC-type uncharacterized transport system, ATPase component General function prediction only 29375760 Common - metallo-beta-lactamase superfamily protein EF1185 158 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 29377715 Common - zinc-binding transcriptional regulator, Cro/CI family EF3272 51 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 29376568 Common - transport ATP-binding protein CydC, putative EF2059 248 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 29375183 Common kdpD sensor histidine kinase KdpD EF0570 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 29377132 Common - hypothetical protein EF2648 36 COG0398 COG0398, Uncharacterized conserved protein Function unknown 29377261 Common - hypothetical protein EF2789 10 COG4483 COG4483, Uncharacterized protein conserved in bacteria Function unknown 29377268 Pathogen - hypothetical protein EF2796 2 COG1289 COG1289, Predicted membrane protein Function unknown 29376972 Common - hypothetical protein EF2479 6 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 29375074 Pathogen - hypothetical protein EF0442 1 None None None 29376116 Common - TPR domain protein EF1553 46 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 29374686 Common - bifunctional maltose and glucose-specific PTS system components IICB EF0028 55 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 29375252 Pathogen - hypothetical protein EF0653 1 None None None 29376280 Common - EbsC protein EF1730 125 COG2606 EbsC, Uncharacterized conserved protein Function unknown 29376760 Common - site-specific recombinase, phage integrase family EF2255 172 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 29377187 Pathogen - hypothetical protein EF2707 1 None None None 29377458 Common - hypothetical protein EF2996 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 29377664 Common - transcriptional regulator, putative EF3216 14 COG3933 COG3933, Transcriptional antiterminator Transcription 29375113 Common - aggregation substance EF0485 6 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376293 Common - general stress protein, putative EF1744 5 COG4980 GvpP, Gas vesicle protein General function prediction only 29377536 Common - acetyltransferase, GNAT family EF3079 131 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 29375411 Pathogen - hypothetical protein EF0823 1 None None None 29377746 Common - PTS system, sorbitol-specific IIA component EF3305 23 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 29376655 Common - hypothetical protein EF2146 3 None None None 29376007 Common - conserved hypothetical protein TIGR01671 EF1440 9 None None None 29374761 Common - transcriptional regulator, ArsR family EF0110 64 COG0640 ArsR, Predicted transcriptional regulators Transcription 29376097 Common - hypothetical protein EF1533 7 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 29377562 Common - peptide ABC transporter, peptide-binding protein EF3106 179 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 29377503 Common - PTS system, IIB component EF3045 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29375141 Common - conserved hypothetical protein TIGR00053 EF0513 34 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 29376696 Common - racemase domain protein EF2188 9 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 29375749 Common - glycosyl transferase, WecB/TagA/CpsF family EF1173 108 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 29377126 Common - glycine betaine/L-proline ABC transporter, glycine betaine/L-proline-binding/permease protein EF2642 160 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 29376445 Common clpX ATP-dependent protease ATP-binding subunit EF1917 227 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 29375452 Common - glycine betaine/carnitine/choline ABC transporter, permease protein EF0864 200 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 29377526 Common - hypothetical protein EF3068 15 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 29374943 Pathogen - lipoprotein, putative EF0304 2 None None None 29375049 Common - oxidoreductase, DadA family EF0414 15 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 29376168 Common - hypothetical protein EF1609 23 COG4843 COG4843, Uncharacterized protein conserved in bacteria Function unknown 29376794 Common - transcriptional regulator, Cro/CI family EF2291 10 COG1476 COG1476, Predicted transcriptional regulators Transcription 29374758 Common - transcriptional regulator, Crp/Fnr family EF0107 100 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 29377512 Common - lipoprotein, putative EF3054 13 COG3212 COG3212, Predicted membrane protein Function unknown 29376173 Common parC DNA topoisomerase IV subunit A EF1614 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 29376833 Common - hypothetical protein EF2332 25 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 29376555 Common comG3 competence protein EF2044 8 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 29377151 Common mgtE magnesium transporter EF2668 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 29377723 Common - peptidase, U32 family, putative EF3280 128 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 29377282 Common - tail tape meausure protein EF2813 29 COG5280 COG5280, Phage-related minor tail protein Function unknown 29376647 Pathogen - transcriptional regulator, Cro/CI family EF2138 1 None None None 29375285 Common - ABC transporter, ATP-binding protein EF0688 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 29375854 Common - major tail protein EF1285 6 None None None 29376900 Pathogen - hypothetical protein EF2405 1 None None None 29375016 Common - death-on-curing family protein EF0379 33 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 29375675 Common - collagen adhesin protein EF1099 10 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29377550 Common - hypothetical protein EF3093 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 29375032 Common - hypothetical protein EF0396 190 COG0628 PerM, Predicted permease General function prediction only 29376979 Common glf UDP-galactopyranose mutase EF2487 63 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 29375705 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase EF1129 56 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 29374922 Common fabF-1 3-oxoacyl-(acyl-carrier-protein) synthase II EF0283 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29375302 Common - hypothetical protein EF0705 3 None None None 29374727 Common - transcriptional regulator, Cro/CI family EF0073 2 None None None 29377540 Common - iron compound ABC transporter, ATP-binding protein EF3083 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 29375068 Common - hypothetical protein EF0436 40 COG3254 COG3254, Uncharacterized conserved protein Function unknown 29375309 Common - hypothetical protein EF0713 7 None None None 29376628 Pathogen - hypothetical protein EF2119 1 None None None 29376621 Pathogen - hypothetical protein EF2112 1 None None None 29377114 Common - hypothetical protein EF2629 20 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 29375522 Common - ABC transporter, ATP-binding/TOBE domain protein EF0938 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 29377577 Common - protein phosphatase 2C, putative EF3121 137 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 29375081 Common - mandelate racemase/muconate lactonizing enzyme family protein EF0450 135 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 29375439 Pathogen - hypothetical protein EF0851 1 None None None 29375655 Common - acetyltransferase, GNAT family EF1077 17 COG0456 RimI, Acetyltransferases General function prediction only 29377657 Common - ABC transporter, ATP-binding protein EF3209 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 29377218 Common - hypothetical protein EF2742 43 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 29375800 Common - hypothetical protein EF1227 116 COG0431 COG0431, Predicted flavoprotein General function prediction only 29376199 Common codY transcriptional repressor CodY EF1645 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 29377326 Common thrS threonyl-tRNA synthetase EF2858 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 29377549 Common - glyoxalase family protein EF3092 40 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 29376365 Common - response regulator EF1822 23 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 29375683 Pathogen - hypothetical protein EF1107 1 None None None 29375807 Common - ABC transporter, substrate-binding protein, putative EF1234 10 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 29376083 Pathogen - hypothetical protein EF1517 1 None None None 29377020 Pathogen - hypothetical protein EF2531 1 None None None 29377571 Common - hypothetical protein EF3115 36 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 29376214 Common bkdA branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit EF1660 160 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 29376157 Common - lipoprotein, putative EF1596 8 None None None 29375890 Common - hypothetical protein EF1322 5 None None None 29375021 Common - hypothetical protein EF0384 4 None None None 29374964 Common - DNA polymerase, putative EF0325 70 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 29375940 Common - DHH family protein EF1373 80 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 29375194 Common - hypothetical protein EF0582 8 None None None 29375079 Common menD 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase EF0448 106 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 29377209 Common - CBS domain protein EF2732 7 COG0517 COG0517, FOG: CBS domain General function prediction only 29375817 Common - oxidoreductase, Gfo/Idh/MocA family EF1244 172 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 29374870 Common rplO 50S ribosomal protein L15 EF0226 220 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 29377013 Common - sortase family protein EF2524 15 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 29375188 Common - cation ABC transporter, permease protein EF0576 188 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 29377745 Common mipB fructose-6-phosphate aldolase EF3304 104 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 29377623 Common - hypothetical protein EF3173 9 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 29377022 Common - FtsK/SpoIIIE family protein EF2533 21 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 29377772 Common - pheromone cCF10 percursor/lipoprotein, 60 kDa EF3331 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 29375723 Common pyrG CTP synthetase EF1147 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 29376516 Pathogen - hypothetical protein EF1995 1 None None None 29375278 Common - hypothetical protein EF0681 17 COG3679 COG3679, Uncharacterized conserved protein Function unknown 29376443 Pathogen - hypothetical protein EF1915 1 None None None 29375157 Common - site-specific recombinase, resolvase family EF0534 104 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 29377620 Common - HD/KH domain protein EF3170 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 29376872 Common - DNA polymerase III, epsilon subunit/ATP-dependent helicase DinG EF2374 206 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 29374739 Pathogen - hypothetical protein EF0086 1 None None None 29376879 Common gdh glucose 1-dehydrogenase EF2382 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29375681 Pathogen - hypothetical protein EF1105 1 None None None 29375503 Common - acetyltransferase, GNAT family EF0919 43 COG0456 RimI, Acetyltransferases General function prediction only 29376081 Common - transcription antiterminator, bglG family EF1515 29 COG3711 BglG, Transcriptional antiterminator Transcription 29375259 Common - MATE efflux family protein EF0660 114 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 29376135 Pathogen - hypothetical protein EF1572 1 None None None 29376046 Common - hypothetical protein EF1479 18 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 29376419 Common - hypothetical protein EF1890 9 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 29376137 Common - Na+/H+ antiporter, putaive EF1574 79 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 29376726 Common - sensor histidine kinase EF2219 104 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 29377566 Common - peptide ABC transporter, ATP-binding protein EF3110 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 29376438 Common - hypothetical protein EF1910 9 COG4129 COG4129, Predicted membrane protein Function unknown 29375369 Common - hypothetical protein EF0778 2 None None None 29375275 Common - phosphoglucomutase/phosphomannomutase family protein EF0677 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 29375978 Common - glycosyl hydrolase, family 4 EF1411 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 29375911 Common - sugar ABC transporter, permease protein EF1344 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 29374694 Common - hypothetical protein EF0036 67 COG2378 COG2378, Predicted transcriptional regulator Transcription 29376685 Common - bacterial sugar transferase EF2177 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 29375667 Common - von Willebrand factor type A domain protein EF1091 13 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 29376172 Common pflB formate acetyltransferase EF1613 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 29375533 Common eutD phosphotransacetylase EF0949 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 29377242 Common - hypothetical protein EF2768 5 None None None 29376491 Common - phosphomethylpyrimidine kinase, putative EF1969 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 29376392 Common panD aspartate alpha-decarboxylase EF1858 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 29375190 Common - helix-turn-helix protein, iron-dependent repressor family EF0578 3 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 29377158 Common - adaptor protein EF2677 13 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 29376850 Common - hypothetical protein EF2349 5 None None None 29377403 Common - cold-shock domain family protein EF2939 167 COG1278 CspC, Cold shock proteins Transcription 29376408 Pathogen - hypothetical protein EF1879 6 None None None 29376462 Common - hypothetical protein EF1936 5 None None None 29376581 Common - aminotransferase, class V EF2072 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 29376432 Common - glycerophosphoryl diester phosphodiesterase family protein EF1904 66 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 29376400 Common - permease, putative EF1869 10 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 29376632 Pathogen - hypothetical protein EF2123 1 None None None 29374782 Pathogen - hypothetical protein EF0131 1 None None None 29377300 Pathogen - hypothetical protein EF2832 2 None None None 29377582 Common gmk guanylate kinase EF3127 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 29377331 Common - endo-beta-N-acetylglucosaminidase EF2863 8 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 29376950 Common pycA pyruvate carboxylase EF2456 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 29375897 Pathogen - hypothetical protein EF1330 1 None None None 29377189 Common ebgA cryptic beta-D-galactosidase subunit alpha EF2709 73 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 29377427 Common - esterase, putative EF2963 61 COG0657 Aes, Esterase/lipase Lipid metabolism 29377483 Common - polysaccharide lyase, family 8 EF3023 18 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 29375004 Common - hypothetical protein EF0366 66 COG1801 COG1801, Uncharacterized conserved protein Function unknown 29376386 Pathogen - hypothetical protein EF1848 1 None None None 29376362 Common - coccolysin EF1818 45 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 29374665 Common recF recombination protein F EF0004 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 29377385 Pathogen - hypothetical protein EF2921 1 None None None 29377202 Common - peptidase, M42 family EF2724 79 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 29377250 Common - hydroxyethylthiazole kinase, putative EF2777 76 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 29377000 Common - AzlC family protein EF2509 106 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 29375743 Common fba fructose-bisphosphate aldolase EF1167 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 29376789 Common - ParB-like nuclease domain protein EF2286 56 COG1475 Spo0J, Predicted transcriptional regulators Transcription 29377542 Common - iron compound ABC transporter, permease protein EF3085 191 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 29375378 Common - transcriptional regulator, TetR family EF0787 33 COG1309 AcrR, Transcriptional regulator Transcription 29375304 Pathogen - hypothetical protein EF0707 1 None None None 29375059 Common - gluconate 5-dehydrogenase EF0426 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29375759 Common dapA dihydrodipicolinate synthase EF1184 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 29376797 Common vanB D-alanine--D-lactate ligase EF2294 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 29377751 Common - sorbitol-6-phosphate 2-dehydrogenase EF3310 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 29377690 Pathogen - hypothetical protein EF3247 1 None None None 29374877 Common rpoA DNA-directed RNA polymerase subunit alpha EF0233 217 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 29375250 Common lplA-1 lipoate-protein ligase A EF0650 79 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 29376099 Common - hypothetical protein EF1535 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 29376332 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase EF1785 180 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 29376339 Common ilvE branched-chain amino acid aminotransferase EF1793 199 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 29375420 Common - hypothetical protein EF0832 11 None None None 29376746 Common - hypothetical protein EF2239 4 None None None 29375315 Common - transcriptional regulator, DeoR family EF0719 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 29375430 Common - hypothetical protein EF0842 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 29375865 Common - transcriptional regulator, PadR family EF1297 57 COG1695 COG1695, Predicted transcriptional regulators Transcription 29377752 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA EF3311 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 29376122 Common - hypothetical protein EF1559 31 COG5496 COG5496, Predicted thioesterase General function prediction only 29376706 Common - glycosyl transferase, group 4 family protein EF2198 226 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 29377733 Common serS-2 seryl-tRNA synthetase EF3292 246 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 29376546 Pathogen - hypothetical protein EF2034 1 None None None 29377681 Common rpoC DNA-directed RNA polymerase subunit beta' EF3237 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 29375957 Common fdhA NAD-dependent formate dehydrogenase, alpha subunit EF1390 216 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 29377288 Pathogen - hypothetical protein EF2819 2 None None None 29376594 Common - hypothetical protein EF2085 32 COG4823 AbiF, Abortive infection bacteriophage resistance protein Defense mechanisms 29374839 Common fhuG ferrichrome ABC transporter, permease protein EF0193 170 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 29376642 Pathogen - hypothetical protein EF2133 1 None None None 29375235 Common - decarboxylase, putative EF0634 83 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 29377636 Common - hypothetical protein EF3186 7 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 29375349 Pathogen - hypothetical protein EF0756 1 None None None 29376998 Common - hypothetical protein EF2507 3 None None None 29376733 Common - ABC transporter, ATP-binding/permease protein EF2226 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 29375852 Common - transcriptional regulator, RinA family EF1283 4 None None None 29376856 Common clpB ATP-dependent Clp protease, ATP-binding subunit ClpB EF2355 225 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 29376991 Pathogen - hypothetical protein EF2499 1 None None None 29376030 Common - hypothetical protein EF1463 12 COG4834 COG4834, Uncharacterized protein conserved in bacteria Function unknown 29376936 Common - phosphate transporter family protein EF2442 168 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 29374691 Pathogen - hypothetical protein EF0033 1 None None None 29375607 Common - hydrolase, alpha/beta hydrolase fold family EF1028 158 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 29376957 Common - voltage-gated chloride channel family protein EF2463 155 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 29377701 Common - hypothetical protein EF3258 10 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 29377169 Common sbcC exonuclease SbcC EF2689 134 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 29377348 Common fabD acyl-carrier-protein S-malonyltransferase EF2882 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 29374898 Common mfd transcription-repair coupling factor EF0257 237 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 29377767 Common - hypothetical protein EF3326 3 None None None 29376233 Common - carboxyl-terminal protease EF1679 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 29377435 Common - amidinotransferase family protein EF2972 32 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 29376482 Common - hypothetical protein EF1959 3 None None None 29375557 Common - hypothetical protein EF0974 7 COG1694 MazG, Predicted pyrophosphatase General function prediction only 29377557 Pathogen - hypothetical protein EF3101 2 None None None 29375240 Common - low temperature requirement C protein, putative EF0639 13 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 29377771 Common - jag protein, putative EF3330 68 COG1847 Jag, Predicted RNA-binding protein General function prediction only 29376110 Common cmk cytidylate kinase EF1547 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 29376753 Common - hypothetical protein EF2248 32 None None None 29376967 Common - ribosomal-protein-alanine acetyltransferase, putative EF2474 183 COG0456 RimI, Acetyltransferases General function prediction only 29376285 Pathogen - hypothetical protein EF1735 1 None None None 29376226 Common - permease protein, putative EF1672 208 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 29375843 Common infB translation initiation factor IF-2 EF1274 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 29377074 Common - inosine-uridine preferring nucleoside hydrolase EF2587 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 29374856 Common rplV 50S ribosomal protein L22 EF0211 231 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 29374683 Common - hypothetical protein EF0025 13 COG3247 HdeD, Uncharacterized conserved protein Function unknown 29377144 Common - diacylglycerol kinase catalytic domain protein EF2661 80 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 29376574 Common - hypothetical protein EF2065 5 COG4699 COG4699, Uncharacterized protein conserved in bacteria Function unknown 29377219 Common - hypothetical protein EF2743 8 COG5523 COG5523, Predicted integral membrane protein Function unknown 29377758 Common - oxaloacetate decarboxylase EF3317 178 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 29375936 Common - transcriptional regulator, Cro/CI family EF1369 13 None None None 29375124 Pathogen - hypothetical protein EF0496 1 None None None 29375833 Common - sulfatase domain protein EF1264 51 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 29375389 Common - autolysin EF0799 113 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 29374832 Pathogen - hypothetical protein EF0184 1 None None None 29377085 Common - transcriptional antiterminator, bglG family EF2599 29 COG3711 BglG, Transcriptional antiterminator Transcription 29376265 Common pyrF orotidine 5'-phosphate decarboxylase EF1713 162 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 29376520 Pathogen - hypothetical protein EF2004 1 None None None 29376845 Pathogen - hypothetical protein EF2344 1 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 29376041 Common - LysM domain protein EF1474 3 None None None 29375562 Common xseB exodeoxyribonuclease VII, small subunit EF0980 119 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 29374827 Common - basic membrane protein family EF0177 80 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 29376129 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase EF1566 231 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 29374825 Common cdd cytidine deaminase EF0175 116 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 29375262 Common - hypothetical protein EF0663 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 29374816 Common - site-specific recombinase, phage integrase family EF0166 125 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 29377401 Common - hypothetical protein EF2937 2 None None None 29374930 Common celA 6-phospho-beta-glucosidase EF0291 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 29375090 Common - N-acetylmuramic acid-6-phosphate etherase EF0459 88 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 29375334 Common - deoxynucleoside kinase EF0740 39 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 29377350 Common acpP acyl carrier protein EF2884 167 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 29377671 Pathogen - hypothetical protein EF3224 1 None None None 29375827 Pathogen - hypothetical protein EF1258 1 None None None 29375479 Common - glycerol dehydrogenase, putative EF0895 61 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 29375702 Common - PTS system, IIA component EF1126 34 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 29376567 Common - transport ATP-binding protein CydD, putative EF2058 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 29376481 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein EF1958 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 29375839 Common - hypothetical protein EF1270 177 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 29375088 Common - PTS system, IIB component EF0457 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 29377397 Common - redox-sensing transcriptional repressor Rex EF2933 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 29375963 Common - molybdenum cofactor biosynthesis family protein, putative EF1396 77 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 29375543 Common - endonuclease/exonuclease/phosphatase family protein EF0960 4 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 29376649 Pathogen - hypothetical protein EF2140 1 None None None 29376474 Common - hypothetical protein EF1949 25 COG4898 COG4898, Uncharacterized protein conserved in bacteria Function unknown 29376413 Common - transposase, IS116/IS110/IS902 family EF1884 65 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 29375964 Common - molybdenum ABC transporter, molybdenum-binding protein EF1397 154 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 29376869 Common asnC asparaginyl-tRNA synthetase EF2371 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 29377441 Common - PTS system, IIC component EF2978 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 29374731 Common - hypothetical protein EF0078 2 COG5547 COG5547, Small integral membrane protein Function unknown 29375919 Common - magnesium-translocating P-type ATPase EF1352 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 29375098 Common - MgtC family protein EF0467 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 29375492 Pathogen - hypothetical protein EF0908 1 COG5108 RPO41, Mitochondrial DNA-directed RNA polymerase Transcription 29375994 Pathogen - hypothetical protein EF1427 1 None None None 29377538 Common - pheromone binding protein EF3081 195 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism