Erwinia carotovora subsp. atroseptica SCRI1043, complete genome NC_004547 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 50119143 Common - methyl-accepting chemotaxis protein ECA0183 159 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50119012 Common uspA universal stress protein A ECA0050 40 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 50121827 Pathogen - hypothetical protein ECA2903 1 None None None 50119511 Common - hypothetical protein ECA0562 2 None None None 50120887 Pathogen osmB lipoprotein ECA1959 1 None None None 50121952 Pathogen - hypothetical protein ECA3029 1 None None None 50121983 Common pdxB erythronate-4-phosphate dehydrogenase ECA3060 227 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 50122494 Common garR tartronate semialdehyde reductase ECA3573 172 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 50119962 Common aepA exoenzyme regulatory protein ECA1022 110 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 50122780 Common ksgA dimethyladenosine transferase ECA3859 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 50120399 Common - putative sugar ABC transporter, ATP-binding protein ECA1460 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 50119634 Common sfsB sugar fermentation stimulation protein ECA0686 26 COG3423 Nlp, Predicted transcriptional regulator Transcription 50121861 Common nifB femo cofactor biosynthesis protein ECA2937 66 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 50120489 Pathogen - hypothetical protein ECA1554 1 None None None 50121825 Pathogen - hypothetical protein ECA2901 2 None None None 50120174 Common hypA hydrogenase nickel incorporation protein ECA1235 49 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 50119499 Pathogen - putative plasmid protein protein ECA0550 1 None None None 50121603 Common rimK ribosomal protein S6 modification protein ECA2679 157 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 50122475 Common - hypothetical protein ECA3554 163 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 50121835 Common - putative DNA-binding protein ECA2911 51 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 50121893 Common - ABC transporter permease protein ECA2969 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50120971 Pathogen - hypothetical protein ECA2043 2 None None None 50120430 Common fbpC ferric transporter ATP-binding subunit ECA1492 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50120793 Common sufS selenocysteine lyase ECA1863 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 50123148 Common ilvM acetolactate synthase 2 regulatory subunit ECA4228 22 COG3978 COG3978, Acetolactate synthase (isozyme II), small (regulatory) subunit Function unknown 50120310 Common tolR colicin uptake protein TolR ECA1371 106 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 50121001 Common - probable oxidoreductase ECA2073 187 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 50120141 Common rcsC hybrid sensory kinase in two-component regulatory system with RcsB and YojN ECA1202 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50120926 Common - putative lipoprotein ECA1999 9 COG3042 Hlx, Putative hemolysin General function prediction only 50122102 Common - PTS system, glucose-specific IIbc component (partial) ECA3180 44 COG1264 PtsG, Phosphotransferase system IIB components Carbohydrate transport and metabolism 50122080 Common sdaC serine transporter ECA3158 39 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 50120655 Common fliJ flagellar biosynthesis chaperone ECA1722 39 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 50123269 Common - hypothetical protein ECA4349 8 None None None 50119674 Common deoB phosphopentomutase ECA0729 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 50123179 Common cytR DNA-binding transcriptional regulator CytR ECA4259 126 COG1609 PurR, Transcriptional regulators Transcription 50120507 Common - probable transporter ECA1573 220 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119920 Common - autotransporter ECA0980 130 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 50122220 Common cysU sulfate ABC transporter permease protein ECA3298 239 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 50122529 Common - hypothetical protein ECA3608 15 COG3061 OapA, Cell envelope opacity-associated protein A Cell envelope biogenesis, outer membrane 50121685 Common - hypothetical protein ECA2761 79 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 50122775 Common rluA ribosomal large subunit pseudouridine synthase A ECA3854 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 50122817 Common rob right origin-binding protein ECA3896 125 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50119079 Common aldA aldehyde dehydrogenase A ECA0118 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50121906 Common emrE multidrug efflux protein ECA2982 135 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 50121539 Common - conserved phage protein (thought to be involved in host lysis) ECA2614A 4 None None None 50119918 Common - hypothetical protein ECA0978 24 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 50120354 Common - hypothetical protein ECA1415 218 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 50122214 Common - putative oxidoreductase ECA3292 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 50122516 Common - hypothetical protein ECA3595 99 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 50122058 Common - hypothetical protein ECA3135 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 50120805 Common nrfA cytochrome c nitrite reductase ECA1875 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 50123303 Common - hypothetical protein ECA4385 18 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 50122253 Common - ABC transporter, permease protein ECA3331 183 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 50123347 Common - putative transposase ECA4429 26 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 50122417 Common - putative transcriptional regulator ECA3496 69 COG1737 RpiR, Transcriptional regulators Transcription 50120894 Common - putative transcriptional repressor ECA1966 120 COG1609 PurR, Transcriptional regulators Transcription 50121608 Common - deoxyribose-phosphate aldolase ECA2684 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 50122933 Common rpmD 50S ribosomal protein L30 ECA4013 155 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 50119926 Common ptsP fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain ECA0986 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 50122744 Common ftsL cell division protein FtsL ECA3822 41 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 50121594 Common artM arginine transporter permease subunit ArtM ECA2670 170 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 50120371 Common - putative glycosyl transferase ECA1432 134 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 50123278 Common - hypothetical protein ECA4358 71 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119282 Common - hypothetical protein ECA0322 41 COG3107 LppC, Putative lipoprotein General function prediction only 50121522 Pathogen - hypothetical protein ECA2598 1 None None None 50122946 Common rplV 50S ribosomal protein L22 ECA4026 226 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 50120700 Common - Isochorismatase family protein ECA1767 82 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 50122628 Common - putative phage-related DNA-binding protein ECA3707 9 None None None 50122419 Pathogen - hypothetical protein ECA3498 1 None None None 50123086 Common glpT sn-glycerol-3-phosphate transporter ECA4166 82 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50120937 Pathogen - hypothetical protein ECA2010 2 None None None 50121079 Common - amino acid ABC transporter ATP-binding protein (partial) ECA2151 67 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50120566 Pathogen - hypothetical protein ECA1634 1 None None None 50121146 Common - putative cellulase ECA2220 14 COG4305 COG4305, Endoglucanase C-terminal domain/subunit and related proteins Carbohydrate transport and metabolism 50123383 Common - predicted hydrolase ECA4466 99 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 50122331 Common - DnaG primase-like protein ECA3407 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50119518 Common - hypothetical protein ECA0569 22 None None None 50119241 Common - hypothetical protein ECA0281 61 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 50119782 Common smpA hypothetical protein ECA0839 59 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 50121585 Common - hypothetical protein ECA2661 49 COG2431 COG2431, Predicted membrane protein Function unknown 50120648 Common fliQ flagellar biosynthesis protein FliQ ECA1715 109 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 50121099 Common - hypothetical protein ECA2171 12 None None None 50122402 Common - hypothetical protein ECA3479 7 None None None 50122696 Common - hypothetical protein ECA3774 29 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 50122996 Common - ABC transporter, substrate binding protein ECA4076 184 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50121266 Common - putative nitroreductase ECA2338 80 COG0778 NfnB, Nitroreductase Energy production and conversion 50119831 Common - two-component system response regulator ECA0889 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50120880 Common - glycerol kinase ECA1952 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 50121498 Common citC [citrate [pro-3s]-lyase] ligase ECA2574 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 161501878 Common - predicted inner membrane protein ECA1855 86 COG0628 PerM, Predicted permease General function prediction only 50122845 Common - hypothetical protein ECA3925 126 COG1678 COG1678, Putative transcriptional regulator Transcription 50123181 Common hslV ATP-dependent protease peptidase subunit ECA4261 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 50119274 Common arcB aerobic respiration control sensor protein ArcB ECA0314 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50121313 Common manX PTS system, mannose-specific IIab component ECA2385 88 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 50119685 Common budA alpha-acetolactate decarboxylase ECA0740 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 50121527 Common - putative phage tail protein E ECA2603 18 None None None 50123218 Common - putative biopolymer transport protein ECA4298 122 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 50122990 Common pelZ pectate lyase ECA4070 16 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 50123187 Common glpK glycerol kinase ECA4267 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 50122104 Common - probable oxidoreductase ECA3182 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 50122520 Common - hypothetical protein ECA3599 15 None None None 50121415 Common - putative maltoporin ECA2490 20 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 50119091 Common - hypothetical protein ECA0130 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 50121194 Common add adenosine deaminase ECA2266 112 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 50121056 Common - hypothetical protein ECA2128 11 None None None 50123226 Pathogen - hypothetical protein ECA4306 1 None None None 50121507 Common hisD histidinol dehydrogenase ECA2583 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 50119358 Pathogen - putative phage-related protein ECA0400 2 None None None 50122116 Common - lipid kinase ECA3194 111 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 50119338 Common - hypothetical protein ECA0379 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 161501880 Common - hypothetical protein ECA0838 70 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 50119037 Common - ABC-type transporter, substrate binding protein ECA0075 191 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50123034 Common - putative lysine/ornithine decarboxylase ECA4114 101 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 50121881 Common nifJ pyruvate-flavodoxin oxidoreductase ECA2957 114 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 50122164 Common - ABC transporter permease (FecCD-family) ECA3242 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50121591 Common artP arginine transporter ATP-binding subunit ECA2667 249 COG4161 ArtP, ABC-type arginine transport system, ATPase component Amino acid transport and metabolism 50122325 Common - putative phage regulatory protein ECA3401 28 COG1476 COG1476, Predicted transcriptional regulators Transcription 50122635 Common - putative phage-related lytic transglycosylase ECA3714 72 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 50119663 Common pnp polynucleotide phosphorylase/polyadenylase ECA0716 243 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 50120330 Common modE DNA-binding transcriptional dual regulator ECA1391 64 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 50123095 Common - hypothetical protein ECA4175 100 COG2962 RarD, Predicted permeases General function prediction only 50119618 Pathogen - hypothetical protein ECA0670 1 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 50123008 Common gph phosphoglycolate phosphatase ECA4088 203 COG0546 Gph, Predicted phosphatases General function prediction only 50120337 Common - putativeoxidoreductase ECA1398 159 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50119135 Common pagP palmitoyl transferase for Lipid A ECA0175 14 None None None 50122097 Common malE maltose-binding periplasmic protein ECA3175 107 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 50123418 Common - hypothetical protein ECA4502 26 COG4648 COG4648, Predicted membrane protein Function unknown 50121410 Common znuC high-affinity zinc transporter ATPase ECA2485 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 50119790 Common - putative mutT/NUDIX family protein ECA0847 144 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 50120383 Common gnd 6-phosphogluconate dehydrogenase ECA1444 187 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 50122723 Common guaC guanosine 5'-monophosphate oxidoreductase ECA3801 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 50119844 Common norV anaerobic nitric oxide reductase flavorubredoxin ECA0902 123 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 50121168 Common - putative lipoprotein ECA2240 38 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 50122860 Common - putative 4Fe-4S binding protein ECA3940 137 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 50123340 Common - ABC transporter permease protein ECA4422 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50120783 Common ppsA phosphoenolpyruvate synthase ECA1853 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 50120776 Common hemS hemin transport protein ECA1846 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 50121548 Common - phage terminase, ATPase subunit P ECA2623 22 COG5484 COG5484, Uncharacterized conserved protein Function unknown 50122820 Common trpR Trp operon repressor ECA3899 22 COG2973 TrpR, Trp operon repressor Transcription 50119493 Common - alternative C-terminus for the PilV protein (fragment) ECA0545 14 None None None 50119982 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase ECA1042 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 50119588 Common - hypothetical protein ECA0639 16 COG4575 ElaB, Uncharacterized conserved protein Function unknown 50122825 Common - putative zinc-binding dehydrogenase ECA3904 148 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 50121690 Common - hypothetical protein ECA2766 41 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 50120811 Common nrfG formate-dependent nitrite reductase complex subunit NrfG ECA1881 35 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 50120517 Pathogen - putative integrase ECA1583 1 None None None 50123069 Common glgC glucose-1-phosphate adenylyltransferase ECA4149 161 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 50119307 Common - GntR-family transcriptional regulator ECA0348 87 COG2188 PhnF, Transcriptional regulators Transcription 50121270 Common - hypothetical protein ECA2342 28 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 50121888 Common - putative peptidase ECA2964 141 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 50119481 Common - putative plasmid-related protein ECA0531 15 None None None 50121942 Common nuoK NADH dehydrogenase subunit K ECA3019 166 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 50122039 Common - putative mandelate racemase/muconate lactonizing enzyme ECA3116 108 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50120468 Common dcuB anaerobic C4-dicarboxylate transporter ECA1533 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 50120266 Common nagE PTS system, N-acetylglucosamine-specific IIABC component ECA1327 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50120766 Common edd phosphogluconate dehydratase ECA1836 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 50123143 Common - hypothetical protein ECA4223 7 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 50119852 Common - putative flavoprotein subunit of a reductase ECA0910 78 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 50120588 Pathogen - hypothetical protein ECA1656 3 None None None 50123274 Common - hypothetical protein ECA4354 73 COG1738 COG1738, Uncharacterized conserved protein Function unknown 50120446 Common - hypothetical protein ECA1511 25 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 50120694 Common - putative acylphosphatase ECA1761 72 COG1254 AcyP, Acylphosphatases Energy production and conversion 50122069 Common - UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase ECA3146 198 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 50120293 Common pcp pyrrolidone-carboxylate peptidase ECA1354 55 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 50119647 Common folP dihydropteroate synthase ECA0699 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 50119691 Common - putative transcriptional regulator ECA0746 137 COG1733 COG1733, Predicted transcriptional regulators Transcription 50120641 Common flgG flagellar basal body rod protein FlgG ECA1707 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 50121247 Common - dsDNA-mimic protein ECA2319 18 COG3099 COG3099, Uncharacterized protein conserved in bacteria Function unknown 50120859 Common gloA lactoylglutathione lyase ECA1929 127 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 50121802 Common - putative signal transduction protein ECA2878 144 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50120185 Common hyfB hydrogenase 4 subunit B ECA1246 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 50119052 Common - methyl-accepting chemotaxis protein ECA0091 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50122246 Common - ABC transporter integral membrane protein ECA3324 131 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 50122767 Common thiQ thiamin transporter ATP-binding subunit ECA3846 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 50122302 Common pvcB pyoverdine biosynthesis protein ECA3380 13 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 50119640 Common - hypothetical protein ECA0692 32 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 50122243 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase ECA3321 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 50119484 Common pilN putative Type IV pilus protein ECA0534 26 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 50119526 Common - hypothetical protein ECA0577 22 None None None 50122807 Common - hypothetical protein ECA3886 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50120288 Common phrB deoxyribodipyrimidine photolyase ECA1349 134 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 50122298 Common - LysR-family transcriptional regulator ECA3376 120 COG0583 LysR, Transcriptional regulator Transcription 50122677 Pathogen - hypothetical protein ECA3755 1 None None None 50120096 Common - AsnC-family transcriptional regulator ECA1157 154 COG1522 Lrp, Transcriptional regulators Transcription 50122225 Common mtn 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase ECA3303 119 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 50120323 Common cusB putative copper efflux system protein ECA1384 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50119929 Common ppdA hypothetical protein ECA0989 10 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 50119122 Common waaL2 O-antigen ligase ECA0161 7 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 50121769 Common nosA TonB dependent receptor ECA2845 81 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50122663 Common - putative bacteriophage tail fiber protein ECA3741 26 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 50122404 Common - hypothetical protein ECA3481 2 None None None 50120660 Common fliE flagellar hook-basal body protein FliE ECA1727 73 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 50121201 Common araF L-arabinose-binding periplasmic protein ECA2273 43 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50121212 Common cysB transcriptional regulator CysB ECA2284 187 COG0583 LysR, Transcriptional regulator Transcription 50120754 Common lolD lipoprotein transporter ATP-binding subunit ECA1824 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 50119607 Common - putative signaling membrane protein ECA0659 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50120850 Common - hypothetical protein ECA1920 155 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 50120913 Common - hypothetical protein ECA1986 42 COG3106 COG3106, Predicted ATPase General function prediction only 50119003 Common gmk guanylate kinase ECA0040 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 50120004 Pathogen - hypothetical protein ECA1064 4 None None None 50120010 Common - putative 3-polyprenyl-4-hydroxybenzoate carboxy-lyase ECA1070 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 50119150 Common - GntR-family transcriptional regulator ECA0190 90 COG2188 PhnF, Transcriptional regulators Transcription 50121625 Common ehpC putative phenazine antibiotic biosynthesis protein ECA2701 192 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 50118971 Common trkD potassium transport protein Kup ECA0006 93 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 50121131 Common pntB pyridine nucleotide transhydrogenase ECA2205 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 50121430 Pathogen - hypothetical protein ECA2505 1 None None None 50119764 Common - hypothetical protein ECA0821 81 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 50119008 Common - putative signaling membrane protein ECA0046 163 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 50121729 Common rhlE ATP-dependent RNA helicase RhlE ECA2805 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 50120718 Pathogen - hypothetical protein ECA1785 2 None None None 50121760 Common moeA molybdopterin biosynthesis protein MoeA ECA2836 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 50120309 Common tolQ colicin uptake protein TolQ ECA1370 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 50120527 Common - AraC-family transcriptional regulator ECA1593 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50122499 Common garD D-galactarate dehydratase ECA3578 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 50119534 Common - restriction enzyme beta subunit ECA0585 5 None None None 50121401 Common ptrB protease II ECA2476 101 COG1770 PtrB, Protease II Amino acid transport and metabolism 50122368 Common - hypothetical protein ECA3445 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 50121736 Common - hypothetical protein ECA2812 135 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 50121092 Common ascG asc operon repressor ECA2164 127 COG1609 PurR, Transcriptional regulators Transcription 50121866 Common nifZ nitrogen fixation protein ECA2942 26 None None None 50122129 Common - hypothetical protein ECA3207 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 50123434 Common atpB F0F1 ATP synthase subunit A ECA4518 207 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 50120669 Common - hypothetical protein ECA1736 14 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 50121915 Common nasB nitrite reductase [NAD(P)H] large subunit ECA2991 197 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 50121199 Common araH L-arabinose transporter permease protein ECA2271 136 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 50123354 Common - LacI-family transcriptional regulator ECA4436 128 COG1609 PurR, Transcriptional regulators Transcription 50121437 Common - hypothetical protein ECA2513 3 None None None 50119454 Common - putative capsular polysaccharide bisynthesis protein ECA0503 8 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 50120936 Common - putative exported protease ECA2009 20 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 50121464 Common pncB nicotinate phosphoribosyltransferase ECA2540 81 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 50123230 Common cpxP putative stress resistance protein ECA4310 17 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 50119611 Pathogen - hypothetical protein ECA0663 1 None None None 50121704 Common - hypothetical protein ECA2780 10 None None None 50123172 Common metB cystathionine gamma-synthase ECA4252 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 50120019 Common fecI RNA polymerase sigma factor FecI ECA1079 63 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50119396 Common - ABC transporter ATP binding protein ECA0445 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 50120682 Common - hypothetical protein ECA1749 129 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 50121088 Common - putative peptidase ECA2160 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 50119944 Common - probable hydrolase ECA1004 165 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 50119082 Pathogen - hypothetical protein ECA0121 4 COG3792 COG3792, Uncharacterized protein conserved in bacteria Function unknown 50118976 Common rbsA D-ribose transporter ATP binding protein ECA0011 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 50119324 Common - hypothetical protein ECA0365 77 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 50119707 Pathogen - putative lipoprotein ECA0762 2 None None None 50122608 Common vagC plasmid-associated protein ECA3687 11 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 50120743 Common - hypothetical protein ECA1812 20 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 50122093 Common galT galactose-1-phosphate uridylyltransferase ECA3171 79 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 50121381 Common fsr fosmidomycin resistance protein ECA2455 148 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119600 Common - probable transporter ECA0651 117 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 50120768 Common gntR gluconate utilization system Gnt-I transcriptional repressor ECA1838 126 COG1609 PurR, Transcriptional regulators Transcription 50120942 Common - hypothetical protein ECA2015 51 COG2353 COG2353, Uncharacterized conserved protein Function unknown 50122707 Common - hypothetical protein ECA3785 14 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 50123246 Pathogen - hypothetical protein ECA4326 1 None None None 50122189 Common aggA agglutination protein ECA3267 140 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50119639 Common rpmA 50S ribosomal protein L27 ECA0691 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 50121664 Common - hypothetical protein ECA2740 11 None None None 50123403 Common - putative allophanate hydrolase subunit 2 ECA4487 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 50119867 Common - putative phospholipase ECA0925 75 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 50120167 Common hybC hydrogenase 2 large subunit ECA1228 98 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 50119913 Common - AraC-family transcriptional regulator ECA0973 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50122367 Common - hypothetical protein ECA3444 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 50121355 Common htpX heat shock protein HtpX ECA2427 188 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 50120831 Common narP DNA-binding response regulator in two-component regulatory system with NarQ or NarX ECA1901 219 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50120736 Common holB DNA polymerase III subunit delta' ECA1803 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 50123012 Common aroB 3-dehydroquinate synthase ECA4092 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 50120453 Common - AraC-family transcriptional regulator ECA1518 115 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50123350 Common bglA 6-phospho-beta-glucosidase ECA4432 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50121350 Common thrS threonyl-tRNA synthetase ECA2422 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50122385 Common proA gamma-glutamyl phosphate reductase ECA3462 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 50123344 Common - putative extracellular solute-binding protein ECA4426 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50122127 Common - putative exported choloylglycine hydrolase ECA3205 46 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 50120716 Common - hypothetical protein ECA1783 92 COG3038 CybB, Cytochrome B561 Energy production and conversion 50121779 Common - hypothetical protein ECA2855 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 50120271 Common - methyl-accepting chemotaxis protein ECA1332 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120849 Common - putative electron transport protein ECA1919 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 50120102 Common - conserved hypothetical lipoprotein ECA1163 26 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 50120420 Common - LysR-family transcriptional regulator ECA1482 182 COG0583 LysR, Transcriptional regulator Transcription 50122606 Pathogen - hypothetical protein ECA3685 2 None None None 50119669 Common - putative acetyltransferase ECA0724 93 COG3153 COG3153, Predicted acetyltransferase General function prediction only 50122772 Common - hypothetical protein ECA3851 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50122463 Common cysN sulfate adenylyltransferase subunit 1 ECA3542 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 50121215 Common - hypothetical protein ECA2287 13 None None None 50121343 Common - hypothetical protein ECA2415 20 None None None 50122782 Common apaH diadenosine tetraphosphatase ECA3861 109 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 50120343 Common - hypothetical protein ECA1404 20 COG5276 COG5276, Uncharacterized conserved protein Function unknown 50120165 Common hybA hydrogenase 2 protein HybA ECA1226 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 50121649 Common - hypothetical protein ECA2725 116 COG2855 COG2855, Predicted membrane protein Function unknown 50119884 Common - putative outer membrane usher protein ECA0942 30 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 50121077 Pathogen - hypothetical protein ECA2149 2 None None None 50121269 Common pncA nicotinamidase/pyrazinamidase ECA2341 128 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 50119418 Pathogen - hypothetical protein ECA0467 1 None None None 50121029 Pathogen hrpT type III secretion lipoprotein ECA2101 1 None None None 50119429 Common entE enterobactin synthase subunit E ECA0478 222 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 50122313 Common xerC site-specific tyrosine recombinase XerC ECA3389 215 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50120480 Common - putative AraC-family transcriptional regulator ECA1545 89 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 50120676 Common betT choline transport protein BetT ECA1743 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 50119055 Common aldB aldehyde dehydrogenase B ECA0094 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50123108 Common hemC porphobilinogen deaminase ECA4188 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 50120949 Common chaA calcium/sodium:proton antiporter ECA2022 48 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 50119276 Common elbB isoprenoid biosynthesis protein with amidotransferase-like domain ECA0316 39 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 50122138 Common engA GTP-binding protein EngA ECA3216 226 COG1160 COG1160, Predicted GTPases General function prediction only 50120417 Common - LysR-family transcriptional regulator ECA1479 176 COG0583 LysR, Transcriptional regulator Transcription 50123138 Common putP sodium/proline symporter ECA4218 166 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 50123156 Common - ABC transporter periplasmic binding protein ECA4236 110 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50122432 Common emrR transcriptional repressor MprA ECA3511 84 COG1846 MarR, Transcriptional regulators Transcription 50121391 Common - hypothetical protein ECA2465 8 None None None 50122288 Common csrA carbon storage regulator ECA3366 81 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 50122922 Common trkA potassium transporter peripheral membrane component ECA4002 153 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 50122275 Common - putative two-component response-regulatory protein YehT ECA3353 173 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 50122305 Common - hypothetical protein ECA3382 9 None None None 50122377 Common - bacteriophage regulatory protein ECA3454 10 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 50120120 Common hemH ferrochelatase ECA1181 168 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 50121964 Common - hypothetical protein ECA3041 24 COG3739 COG3739, Uncharacterized integral membrane protein Function unknown 50120244 Common - hypothetical protein ECA1305 159 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 50119113 Common - putative glycosyltransferase ECA0152 8 COG3774 OCH1, Mannosyltransferase OCH1 and related enzymes Cell envelope biogenesis, outer membrane 50120729 Common fabD acyl carrier protein S-malonyltransferase ECA1796 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 50121449 Common - multidrug resistance protein MdtH ECA2525 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122908 Common iclR acetate operon transcriptional repressor IclR ECA3988 123 COG1414 IclR, Transcriptional regulator Transcription 50118994 Common - phosphatase ECA0031 75 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 50119599 Pathogen - hypothetical protein ECA0650 4 None None None 50122709 Common lpdA dihydrolipoamide dehydrogenase ECA3787 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 50123051 Common acrD aminoglycoside/multidrug efflux system ECA4131 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 50120250 Common gltL glutamate/aspartate transport ATP-binding protein ECA1311 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50122200 Common rnc ribonuclease III ECA3278 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 50119749 Pathogen rhiE rhamnogalacturonate lyase ECA0804 2 None None None 50122230 Common - putative aminotransferase ECA3308 202 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50123040 Common - methyl-accepting chemotaxis protein ECA4120 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50119551 Common cfa8A putative oxidoreductase ECA0601 3 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 50119646 Common hflB ATP-dependent metalloprotease ECA0698 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 50120473 Common hasR TonB-dependent heme receptor ECA1538 80 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50120680 Common - hypothetical protein ECA1747 34 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 50121330 Common pelW pectate disaccharide-lyase ECA2402 5 None None None 50120063 Common - hypothetical protein ECA1124 8 None None None 50119239 Common - p-hydroxybenzoic acid efflux subunit AaeB ECA0279 47 COG1289 COG1289, Predicted membrane protein Function unknown 50122349 Common - putative lipoprotein ECA3425 41 None None None 50121452 Common - hypothetical protein ECA2528 16 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 50121909 Common - ArsR-family transcriptional regulator ECA2985 33 COG0640 ArsR, Predicted transcriptional regulators Transcription 50122120 Common - putative zinc-binding dehydrogenase ECA3198 179 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 50123330 Common ssuC putative aliphatic sulfonates transport permease protein ECA4412 204 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50122891 Common frdC fumarate reductase subunit C ECA3971 22 COG3029 FrdC, Fumarate reductase subunit C Energy production and conversion 50118980 Common rbsR transcriptional repressor RbsR ECA0015 129 COG1609 PurR, Transcriptional regulators Transcription 50119840 Common - hypothetical protein ECA0898 54 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 50121566 Common - LysR-family transcriptional regulator ECA2642 166 COG0583 LysR, Transcriptional regulator Transcription 50120687 Common - hypothetical protein ECA1754 44 COG1289 COG1289, Predicted membrane protein Function unknown 50121426 Pathogen - hypothetical protein ECA2501 1 None None None 50119187 Common - putative GntR-family transcriptional regulator ECA0227 230 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50123124 Common rffA TDP-4-oxo-6-deoxy-D-glucose transaminase ECA4204 198 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 50123158 Common btuB vitamin B12/cobalamin outer membrane transporter ECA4238 129 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 50120216 Common - hypothetical protein ECA1277 2 None None None 50120892 Common - putative molybdopterin oxidoreductase ECA1964 172 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 50121642 Common - putative iron-containing alcohol dehydrogenase ECA2718 68 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 50120954 Common - hypothetical protein ECA2026 14 None None None 50120826 Common napA periplasmic nitrate reductase ECA1896 185 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 50119430 Common entB enterobactin synthetase component B (isochorismatase) ECA0479 80 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 50122354 Common - hypothetical protein ECA3431 15 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 50121715 Common - putative glutathione S-transferase ECA2791 75 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50121724 Common - hypothetical protein ECA2800 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 50122426 Common - putative hydrolase ECA3505 138 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 50122531 Common rplI 50S ribosomal protein L9 ECA3610 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 50120076 Common - nucleotide-binding protein ECA1137 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 50122657 Common - putative bacteriophage protein ECA3735 43 COG3500 COG3500, Phage protein D General function prediction only 50119026 Common - hypothetical protein ECA0064 25 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 50119030 Common - LysR-family transcriptional regulator ECA0068 93 COG0583 LysR, Transcriptional regulator Transcription 50122642 Common - putative phage-related protein ECA3721 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 50119711 Pathogen - hypothetical protein ECA0766 2 None None None 50119658 Common nusA transcription elongation factor NusA ECA0711 223 COG0195 NusA, Transcription elongation factor Transcription 50121435 Common - hypothetical protein ECA2511 52 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50119299 Common - PTS system, IIbc component ECA0340 67 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 50119256 Common - hypothetical protein ECA0296 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 50120405 Common - hypothetical protein ECA1466 10 COG3668 ParE, Plasmid stabilization system protein General function prediction only 50120361 Common rfbF glucose-1-phosphate cytidylyltransferase ECA1422 162 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 50122552 Common - putative deoxyribonucleotide triphosphate pyrophosphatase ECA3631 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 50120617 Common trg methyl-accepting chemotaxis protein ECA1683 135 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50123058 Common glpG predicted intramembrane serine protease ECA4138 31 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 50119302 Common - probable PTS system regulatory protein ECA0343 30 COG3711 BglG, Transcriptional antiterminator Transcription 50122489 Common mazG nucleoside triphosphate pyrophosphohydrolase ECA3568 157 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 50119326 Common - putative DNA-binding protein ECA0367 16 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 50122954 Common bfd bacterioferritin-associated ferredoxin ECA4034 20 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 50121692 Common glnH glutamine ABC transporter periplasmic protein ECA2768 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50118989 Common hemN coproporphyrinogen III oxidase ECA0026 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 50122876 Common - ABC transporter, substrate binding protein ECA3956 58 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 50123201 Common - putative phage regulatory protein ECA4281 4 COG1396 HipB, Predicted transcriptional regulators Transcription 50123161 Common - DNA-binding transcriptional repressor FabR ECA4241 42 COG1309 AcrR, Transcriptional regulator Transcription 50121285 Common - putative kinase ECA2357 6 COG0645 COG0645, Predicted kinase General function prediction only 50122000 Common - hypothetical protein ECA3077 13 COG5430 COG5430, Uncharacterized secreted protein Function unknown 50121094 Common ascB cryptic 6-phospho-beta-glucosidase ECA2166 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50120994 Common - putative lipoprotein ECA2066 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 50120191 Common hoxN high-affinity nickel transport protein ECA1252 37 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 50119816 Common hemF coproporphyrinogen III oxidase ECA0874 112 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 50123377 Common - putative lipoprotein ECA4460 29 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 50120237 Common lipB lipoyltransferase ECA1298 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 50119210 Common - putative oxidoreductase ECA0250 147 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 50121346 Common pheS phenylalanyl-tRNA synthetase subunit alpha ECA2418 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 50121151 Common - putative acetyltransferase ECA2225 21 COG0456 RimI, Acetyltransferases General function prediction only 50121747 Common bioC biotin synthesis protein ECA2823 186 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50121459 Common - putative RNA methylase ECA2535 163 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 50123134 Common gppA guanosine pentaphosphate phosphohydrolase ECA4214 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 50120521 Common - probable glutathione-S-transferase ECA1587 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50122577 Common - hypothetical protein ECA3656 28 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 50121650 Common nfo endonuclease IV ECA2726 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 50121032 Common - VgrG protein ECA2104 60 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 50123244 Pathogen - hypothetical protein ECA4324 5 None None None 50121510 Common hisH imidazole glycerol phosphate synthase subunit HisH ECA2586 216 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 50119821 Common - putative zinc protease ECA0879 197 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 50121407 Common msbB lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase ECA2482 74 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 50123115 Common - putative amino-acid ABC transporter binding protein ECA4195 170 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50122296 Common - putative signaling membrane protein ECA3374 180 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 50119828 Common cysM cysteine synthase B ECA0886 227 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 50121126 Common - hypothetical protein ECA2200 3 None None None 50122472 Common - periplasmic binding protein precursor ECA3551 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50121977 Common dedD hypothetical protein ECA3054 19 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 50122587 Common - hypothetical protein ECA3666 2 None None None 50123337 Common dgoR galactonate operon transcriptional repressor ECA4419 128 COG2186 FadR, Transcriptional regulators Transcription 50119733 Common - hypothetical protein ECA0788 46 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 50120572 Pathogen - hypothetical protein ECA1640 3 None None None 50121224 Common trpE anthranilate synthase component I ECA2296 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 50119315 Common - hypothetical protein ECA0356 38 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 50121875 Common - probable transporter ECA2951 107 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122266 Common - hypothetical protein ECA3344 31 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 50119349 Common - methyl-accepting chemotaxis protein ECA0390 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50123293 Common - AraC family transcriptional regulator ECA4375 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50120154 Common menE O-succinylbenzoic acid--CoA ligase ECA1215 214 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50123385 Common - binding-protein-dependent transport system inner membrane component ECA4468 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50120049 Common phoB phosphate regulon response regulator ECA1110 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50119704 Common - hypothetical protein ECA0759 47 COG2938 COG2938, Uncharacterized conserved protein Function unknown 50120427 Common lacY galactoside permease ECA1489 23 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 50119804 Common talA transaldolase A ECA0862 183 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 50121013 Common hrpI type III secretion protein ECA2085 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 50122148 Common - 6-phospho-alpha-glucosidase ECA3226 53 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 50119895 Pathogen - hypothetical protein ECA0953 1 None None None 50121363 Common rdgA regulator of pectin lyase production ECA2435 32 COG2932 COG2932, Predicted transcriptional regulator Transcription 50121188 Common - putative transporter ECA2260 163 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120984 Common - putative transport system, permease protein ECA2056 173 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 50119403 Common - putative zinc-binding dehydrogenase ECA0452 101 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 50122843 Common - hypothetical protein ECA3923 190 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 50119129 Common - hypothetical protein ECA0169 61 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 50120495 Common cdh CDP-diacylglycerol pyrophosphatase ECA1560 19 COG2134 Cdh, CDP-diacylglycerol pyrophosphatase Lipid metabolism 50120227 Common - LysR-family transcriptional regulator ECA1288 192 COG0583 LysR, Transcriptional regulator Transcription 50122153 Common - hypothetical protein ECA3231 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 50119162 Common tatD DNase TatD ECA0202 235 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 50121661 Common - putative binding-protein-dependent transporter ECA2737 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 50121856 Common - putative outer membrane efflux lipoprotein ECA2932 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50120055 Common - hypothetical protein ECA1116 63 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 50120133 Common cueR copper efflux regulator ECA1194 139 COG0789 SoxR, Predicted transcriptional regulators Transcription 50120733 Common pabC 4-amino-4-deoxychorismate lyase ECA1800 148 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 50120818 Common dsbE thiol:disulfide interchange protein ECA1888 113 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 50121509 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase ECA2585 216 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 50121298 Common minE cell division topological specificity factor MinE ECA2370 82 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 50119478 Pathogen - hypothetical protein ECA0526 1 None None None 50120869 Common - putative glutamate symport protein ECA1939 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 50123419 Common - acyl carrier protein ECA4503 66 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50123006 Common abgB aminobenzoyl-glutamate utilization protein B ECA4086 92 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 50119769 Common - putative GNAT-family acetyltransferase ECA0826 90 COG0456 RimI, Acetyltransferases General function prediction only 50119384 Common - putative lipoprotein ECA0433 18 None None None 50123370 Common hmsR N-glycosyltransferase PgaC ECA4452 171 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 50120646 Common flgL flagellar hook-associated protein FlgL ECA1712 88 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 50122421 Common - hypothetical protein ECA3500 23 None None None 50119754 Pathogen - hypothetical protein ECA0810 1 None None None 50119549 Pathogen - hypothetical protein ECA0599 3 None None None 50119624 Pathogen - hypothetical protein ECA0676 1 None None None 50122019 Common - ABC-transporter periplasmic-binding component ECA3096 115 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50120552 Pathogen - putative plasmid protein ECA1618 4 None None None 50123395 Common - probable amino acid ABC transporter, permease protein ECA4479 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50122667 Common - LacI-family transcriptional regulator ECA3745 124 COG1609 PurR, Transcriptional regulators Transcription 50122448 Common rcsF outer membrane lipoprotein ECA3527 13 None None None 50119808 Common - putative dihydroxyacetone kinase ECA0866 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 50119954 Pathogen - hypothetical protein ECA1014 1 None None None 50121311 Common - putative isochorismatase ECA2383 69 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 50122430 Common - putative amino acid transporter ECA3509 104 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 50121502 Common citB two-component response regulator ECA2578 196 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 50122711 Common aceE pyruvate dehydrogenase subunit E1 ECA3789 144 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 50120746 Common ndh NADH dehydrogenase ECA1815 201 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 50120677 Common betI transcriptional regulator BetI ECA1744 50 COG1309 AcrR, Transcriptional regulator Transcription 50121995 Common sixA phosphohistidine phosphatase ECA3072 66 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 50119935 Common RecB exonuclease V subunit beta ECA0995 221 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 50120860 Common - hypothetical protein ECA1930 22 COG3313 COG3313, Predicted Fe-S protein General function prediction only 50123222 Common sftP TonB-dependent receptor ECA4302 79 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50121935 Common - probable acetyltransferase ECA3012 49 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 50120109 Common acrA acriflavine resistance protein A ECA1170 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50119413 Common - putative 5-formyltetrahydrofolate cyclo-ligase ECA0462 185 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 50121377 Common potB spermidine/putrescine ABC transporter membrane protein ECA2451 218 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 50122237 Common ligT 2'-5' RNA ligase ECA3315 78 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 50120838 Common - putative membrane-attached phosphoesterase ECA1908 96 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 50120705 Common - hypothetical protein ECA1772 7 None None None 50122193 Common - EAL domain containing protein involved in flagellar function ECA3271 122 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 50120080 Common cyoC cytochrome o ubiquinol oxidase subunit III ECA1141 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 50120591 Common - probable plasmid-related protein ECA1659 35 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 50121675 Pathogen - putative phage-related protein ECA2751 1 None None None 50121798 Common - hypothetical protein ECA2874 10 None None None 50122014 Common - hypothetical protein ECA3091 49 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 50122046 Common - hypothetical protein ECA3123 2 None None None 50122718 Common tsx nucleoside-specific channel-forming protein ECA3796 19 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 50119394 Common - hypothetical protein ECA0443 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 50120547 Common virB10 putative conjugal transfer protein ECA1614 50 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 50122853 Common hflX putative GTPase HflX ECA3933 231 COG2262 HflX, GTPases General function prediction only 50122048 Common - hypothetical protein ECA3125 24 None None None 50119513 Common - hypothetical protein ECA0564 18 None None None 50121766 Common pcaB 3-carboxy-cis,cis-muconate cycloisomerase ECA2842 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 50122736 Common murC UDP-N-acetylmuramate--L-alanine ligase ECA3814 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 50119992 Common cutF lipoprotein involved with copper homeostasis and adhesion ECA1052 23 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 50121491 Pathogen - hypothetical protein ECA2567 1 None None None 50119177 Common secE preprotein translocase subunit SecE ECA0217 68 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 50119779 Common smpB SsrA-binding protein ECA0836 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 50120021 Common - probable transcriptional regulator ECA1081 162 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 50122837 Pathogen - LuxR-family transcriptional regulator ECA3917 1 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 50122756 Common - hypothetical protein ECA3835 11 COG4392 COG4392, Predicted membrane protein Function unknown 50121554 Common - phage DNA adenine methylase ECA2629 98 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 50119232 Common - hypothetical protein ECA0272 56 COG3164 COG3164, Predicted membrane protein Function unknown 50119576 Common ubiA 4-hydroxybenzoate octaprenyltransferase ECA0627 161 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 50121683 Pathogen - hypothetical protein ECA2759 1 None None None 50123032 Common - putative octopine/opine/tauropine dehydrogenase ECA4112 6 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 50121124 Pathogen - hypothetical protein (partial) ECA2198 1 None None None 50123295 Common - putative ethanolamin permease ECA4377 160 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 50121846 Common - LysR-family transcriptional regulator ECA2922 115 COG0583 LysR, Transcriptional regulator Transcription 50120115 Common dnaX DNA polymerase III subunits gamma and tau ECA1176 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 50122563 Common - methyl-accepting chemotaxis protein ECA3642 138 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50122974 Common slyD FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) ECA4054 123 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 50120221 Common atoB acetyl-CoA acetyltransferase ECA1282 177 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 50122698 Common fsaB fructose-6-phosphate aldolase ECA3776 127 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 50122056 Pathogen - hypothetical protein ECA3133 1 None None None 50119770 Common - putative amino acid efflux protein ECA0827 102 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50119462 Pathogen ccdA1 putative toxin addiction system protein ECA0511 5 COG5302 COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid General function prediction only 50122457 Common ftsB cell divison protein FtsB ECA3536 61 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 50119827 Common cysW sulfate/thiosulfate transporter permease subunit ECA0885 217 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 50120129 Common pehN putative polygalacturonase ECA1190 30 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 50119775 Pathogen - putative phage capsid protein (partial) ECA0832 3 None None None 50121756 Common - putative ABC transporter permease protein ECA2832 223 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122977 Common - glutathione-regulated potassium-efflux system ancillary protein KefG ECA4057 64 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 50120603 Pathogen - hypothetical protein ECA1670 1 None None None 50122391 Common dinB DNA polymerase IV ECA3468 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 50122397 Common fadE acyl-CoA dehydrogenase ECA3474 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 50121925 Pathogen - hypothetical protein ECA3001 1 None None None 50120188 Common hydN electron transport protein HydN ECA1249 147 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 50123047 Common - putative permease ECA4127 26 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 50121066 Pathogen - hypothetical protein ECA2138 1 None None None 50121442 Common cutC copper homeostasis protein CutC ECA2518 58 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 50122689 Common - probable short-chain dehydrogenase ECA3767 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50123075 Common asd aspartate-semialdehyde dehydrogenase ECA4155 195 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 50120025 Common - LysR-family transcriptional regulator ECA1085 177 COG0583 LysR, Transcriptional regulator Transcription 50122004 Common fadL long-chain fatty acid outer membrane transporter ECA3081 82 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 50121231 Common ompW outer membrane protein W ECA2303 71 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 50122613 Common - probable acetyltransferase ECA3692 68 COG0456 RimI, Acetyltransferases General function prediction only 50120530 Common - hypothetical protein ECA1596 70 COG0433 COG0433, Predicted ATPase General function prediction only 50120579 Pathogen - hypothetical protein ECA1647 2 None None None 50119460 Common - hypothetical protein ECA0509 9 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 50120755 Common lolE outer membrane-specific lipoprotein transporter subunit LolE ECA1825 166 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 50121148 Common cybC putative soluble cytochrome b562 ECA2222 8 COG3783 CybC, Soluble cytochrome b562 Energy production and conversion 50121791 Common vgrG putative RHS accessory genetic element ECA2867 59 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 50122982 Common prkB phosphoribulokinase ECA4062 54 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 50122166 Pathogen - hypothetical protein ECA3244 1 None None None 50119766 Common cybB cytochrome B561 ECA0823 88 COG3038 CybB, Cytochrome B561 Energy production and conversion 50123084 Common glpB anaerobic glycerol-3-phosphate dehydrogenase subunit B ECA4164 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 50120651 Common fliN flagellar motor switch protein FliN ECA1718 124 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 50121058 Pathogen - hypothetical protein ECA2130 3 None None None 50121833 Pathogen - hypothetical protein ECA2909 2 None None None 50122409 Common - putative aminotransferase ECA3488 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 50121633 Common sanA hypothetical protein ECA2709 41 COG2949 SanA, Uncharacterized membrane protein Function unknown 50120329 Common modF putative molybdenum transport ATP-binding protein ModF ECA1390 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 50120500 Common - putative paraquat-inducible membrane protein ECA1565 55 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 50122051 Common dltA putative D-alanine--poly(phosphoribitol) ligase subunit 1 ECA3128 191 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50122541 Common - hypothetical protein ECA3620 28 COG3766 COG3766, Predicted membrane protein Function unknown 50119093 Common - L-asparaginase ECA0132 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 50119959 Common - Lysine decarboxylase family protein ECA1019 40 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 50120388 Common - chorismate mutase ECA1449 11 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 50119508 Pathogen - hypothetical protein ECA0559 1 None None None 50121741 Common moaA molybdenum cofactor biosynthesis protein A ECA2817 198 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 50123282 Common dctA C4-dicarboxylate transporter DctA ECA4362 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 50123228 Common fieF ferrous iron efflux protein F ECA4308 189 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 50121036 Pathogen - putative lipoprotein ECA2108 3 None None None 50121613 Common - putative lipoprotein ECA2689 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 50119475 Common - hypothetical protein ECA0523 21 None None None 50121800 Common - putative phage-related protein ECA2876 28 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 50123165 Common pdeA phosphodiesterase ECA4245 52 COG1409 Icc, Predicted phosphohydrolases General function prediction only 50120295 Common gltA type II citrate synthase ECA1356 194 COG0372 GltA, Citrate synthase Energy production and conversion 50121008 Common hrcQ type III secretion protein ECA2080 4 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 50121192 Common - hypothetical protein ECA2264 20 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 50119784 Common ppnK inorganic polyphosphate/ATP-NAD kinase ECA0841 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 50123319 Common - hypothetical protein ECA4401 55 COG2985 COG2985, Predicted permease General function prediction only 50121361 Common - putative signaling protein ECA2433 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 50118998 Common - putative purine permease ECA0035 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 50119137 Common - hypothetical protein ECA0177 5 None None None 50120787 Common - hypothetical protein ECA1857 89 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 50120781 Common aroH phospho-2-dehydro-3-deoxyheptonate aldolase ECA1851 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 50122691 Common - putative pyruvate formate-lyase activating enzyme ECA3769 66 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 161501882 Common - hypothetical protein ECA0710 178 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 50119788 Common - hypothetical protein ECA0845 59 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50121315 Common manZ mannose-specific PTS system protein IID ECA2387 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 50123291 Common bcsZ endo-1,4-D-glucanase ECA4373 31 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 50122941 Common rplN 50S ribosomal protein L14 ECA4021 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 50119336 Common - hypothetical protein ECA0377 90 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 50120461 Common - ABC transporter periplasmic binding protein ECA1526 27 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 50120663 Common fliD flagellar capping protein ECA1730 101 COG1345 FliD, Flagellar capping protein Cell motility and secretion 50123374 Common smvA putative methyl viologen resistance protein ECA4457 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120207 Common tldD putative suppressor of the inhibitory activity of the carbon storage regulator CsrA ECA1268 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 50123251 Common gntP inner membrane permease YgbN ECA4331 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 50119984 Common lpxB lipid-A-disaccharide synthase ECA1044 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 50121711 Common - AraC-family transcriptional regulator ECA2787 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50122519 Common - hypothetical protein ECA3598 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 50120813 Common ccmB heme exporter protein B ECA1883 81 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 50120722 Common rne ribonuclease E ECA1789 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 50120638 Common flgD flagellar basal body rod modification protein ECA1704 102 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 50120978 Common - hypothetical protein ECA2050 47 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50121634 Common - hypothetical protein ECA2710 50 COG2311 COG2311, Predicted membrane protein Function unknown 50119084 Pathogen - putative lipoprotein ECA0123 1 None None None 50119356 Pathogen - hypothetical protein ECA0399 3 None None None 50120570 Pathogen - Hns-like DNA-binding protein ECA1638 3 None None None 50122174 Common paeY pectin acetylesterase ECA3252 14 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 50119309 Common - putative iron-containing alcohol dehydrogenase ECA0350 163 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 50120205 Common - putative acetyltransferase ECA1266 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 50122118 Common thiD phosphomethylpyrimidine kinase ECA3196 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 50120279 Common kdpC potassium-transporting ATPase C chain ECA1340 94 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 50120432 Common afuA ABC transporter iron-binding protein ECA1494 114 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 50120151 Common - acyl-CoA thioester hydrolase YfbB ECA1212 74 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 50121944 Common nuoI NADH dehydrogenase subunit I ECA3021 189 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 50120991 Common - ABC transporter ATP-binding protein ECA2063 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 50123260 Common livH branched-chain amino acid transporter permease subunit LivH ECA4340 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 50121829 Pathogen - hypothetical protein ECA2905 6 None None None 50123305 Common bglH beta-glucosidase ECA4387 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50122540 Common - putative lipoprotein ECA3619 9 None None None 50122636 Common - putative phage-related lipoprotein ECA3715 4 None None None 50122155 Common hscA chaperone protein HscA ECA3233 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 50120335 Common - hypothetical protein ECA1396 49 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 50120156 Common - hypothetical protein ECA1217 13 None None None 50120885 Common pyrF orotidine 5'-phosphate decarboxylase ECA1957 165 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 50119141 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase ECA0181 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 50119676 Common fcuA putative ferric siderophore TonB-dependent receptor ECA0731 84 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50119989 Common tilS tRNA(Ile)-lysidine synthetase ECA1049 211 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 50121891 Common - putative dehydratase ECA2967 51 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 50120904 Common sapB peptide transport system permease protein ECA1976 218 COG4168 SapB, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 50119253 Common - D-arabinose 5-phosphate isomerase ECA0293 157 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 50122527 Common - cell morphogenesis/cell wall metabolism regulator ECA3606 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 50119041 Common - methyl-accepting chemotaxis protein ECA0080 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120397 Common idhA putative myo-inositol 2-dehydrogenase ECA1458 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50122777 Common imp organic solvent tolerance protein ECA3856 122 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 50121526 Common - major tail tube protein FII ECA2602 29 COG3498 COG3498, Phage tail tube protein FII General function prediction only 50120924 Pathogen imm colicin immunity protein ECA1997 2 None None None 50122935 Common rplR 50S ribosomal protein L18 ECA4015 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 50121272 Common gapA glyceraldehyde-3-phosphate dehydrogenase ECA2344 220 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 50122921 Common sun 16S rRNA methyltransferase B ECA4001 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 50119398 Common - ABC transporter permease protein ECA0447 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50119569 Common cutA divalent-cation tolerance protein CutA ECA0619 117 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 50120561 Common alpA putative prophage regulatory protein ECA1627 48 COG3311 AlpA, Predicted transcriptional regulator Transcription 50123224 Common - hypothetical protein ECA4304 4 None None None 50122063 Common - hypothetical protein ECA3140 15 None None None 50122989 Common pelC pectate lyase III ECA4069 17 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 50122067 Common - bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase ECA3144 244 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 50118983 Common - hypothetical protein ECA0018 18 COG3084 COG3084, Uncharacterized protein conserved in bacteria Function unknown 50120550 Pathogen virB7 putative conjugal transfer protein ECA1616A 1 None None None 50122621 Common - conserved hypothetical phage-related protein ECA3700 18 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 50121537 Common - putative phage tail protein S ECA2613 15 None None None 50120871 Common acnA aconitate hydratase ECA1941 222 COG1048 AcnA, Aconitase A Energy production and conversion 50119833 Common crr glucose-specific PTS system component ECA0891 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 50120509 Common - MerR-family transcriptional regulator ECA1575 103 COG0789 SoxR, Predicted transcriptional regulators Transcription 161501872 Common - putative phosphatase ECA3036 181 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 50122966 Common - putative serine hydroxymethyltransferase ECA4046 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 50122251 Common - putative acetyltransferase ECA3329 22 COG0456 RimI, Acetyltransferases General function prediction only 50123188 Common glpX fructose 1,6-bisphosphatase II ECA4268 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 50121731 Common cbrC achromobactin transport system permease protein ECA2807 190 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 50121520 Common focA formate transporter ECA2596 97 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 50121972 Common hisQ histidine ABC transporter permease protein ECA3049 171 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 50120670 Common - putative acetyltransferase ECA1737 5 COG0456 RimI, Acetyltransferases General function prediction only 50119149 Common - putative mandelate racemase / muconate lactonizing enzyme ECA0189 107 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50119388 Common - hypothetical protein ECA0437 42 COG3254 COG3254, Uncharacterized conserved protein Function unknown 50123196 Common - Rhs-family protein ECA4276 60 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 50123133 Common rhlB ATP-dependent RNA helicase RhlB ECA4213 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 50122216 Common - TetR-family transcriptional regulator ECA3294 82 COG1309 AcrR, Transcriptional regulator Transcription 50122415 Common - putative amino acid ABC transporter, permease protein ECA3494 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50123101 Common xerC site-specific tyrosine recombinase XerC ECA4181 227 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 50123310 Common dppC dipeptide transporter ECA4392 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122576 Common - hypothetical protein ECA3655 40 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 50120176 Common hycI hydrogenase 3 maturation protease ECA1237 42 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 50121904 Common - hypothetical protein ECA2980 5 None None None 50123288 Pathogen - hypothetical protein ECA4368 5 None None None 50120927 Common ldhA D-lactate dehydrogenase ECA2000 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 50121645 Common hprA glycerate dehydrogenase ECA2721 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 50121601 Common potF putrescine transporter subunit: periplasmic-binding component of ABC superfamily ECA2677 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 50120752 Common mfd transcription-repair coupling factor ECA1821 229 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 50119035 Common - ABC transporter permease protein ECA0073 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50120662 Common fliS flagellar protein FliS ECA1729 92 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 50119105 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase ECA0144 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 50120806 Common nrfB cytochrome c-type protein NrfB ECA1876 22 None None None 50120852 Common norM multidrug efflux protein ECA1922 169 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 50120223 Common atoD acetyl-CoA:acetoacetyl-CoA transferase subunit alpha ECA1284 102 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 50122187 Common - hypothetical protein ECA3265 13 None None None 50121706 Common prtE protease secretion protein ECA2782 119 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 50121335 Common kdgM oligogalacturonate-specific porin ECA2407 12 None None None 50122525 Common - hypothetical protein ECA3604 11 None None None 50121627 Pathogen ehpA putative phenazine antibiotic biosynthesis protein ECA2703 3 None None None 50119536 Pathogen - hypothetical protein ECA0586A 1 None None None 50119370 Common - putative bacteriophage regulatory protein ECA0414 10 None None None 50119531 Common - putative plasmid-related protein ECA0582 26 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 50120940 Common rstA DNA-binding response regulator in two-component regulatory system with RstB ECA2013 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50121210 Common nth endonuclease III ECA2282 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 50120218 Common - hypothetical protein ECA1279 24 COG3813 COG3813, Uncharacterized protein conserved in bacteria Function unknown 50120307 Common - hypothetical protein ECA1368 16 COG3790 COG3790, Predicted membrane protein Function unknown 50121466 Common ompN outer membrane protein ECA2542 30 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 50121133 Common fnr fumarate/nitrate reduction transcriptional regulator ECA2207 156 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 50120529 Common - hypothetical protein ECA1595 16 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 50122123 Common - hypothetical protein ECA3201 55 COG0730 COG0730, Predicted permeases General function prediction only 50122089 Common ohr organic hydroperoxide resistance protein ECA3167 96 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 50123396 Common - probable amino acid ABC transporter, permease protein ECA4480 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50119120 Common waaG lipopolysaccharide core biosynthesis protein ECA0159 167 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 50121155 Common - hypothetical protein ECA2228 10 None None None 50121583 Common cspD cold shock-like protein ECA2659 177 COG1278 CspC, Cold shock proteins Transcription 50121169 Common - hypothetical protein ECA2241 7 None None None 50122622 Common - conserved hypothetical phage-related protein ECA3701 4 None None None 50121135 Common - putative oxidoreductase ECA2209 141 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50119376 Common - putative outer membrane efflux protein ECA0425 104 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50119538 Common - putative plasmid-related protein ECA0588 3 None None None 50119694 Common - putative binding-protein-dependent transport system protein ECA0749 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 50122034 Common pehX exo-poly-alpha-D-galacturonosidase ECA3111 24 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 50119304 Common parC DNA topoisomerase IV subunit A ECA0345 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 50121810 Pathogen - hypothetical protein ECA2886 1 None None None 50119001 Common spoT bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase ECA0038 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 50119943 Common - putative tetR-family transcription factor ECA1003 73 COG1309 AcrR, Transcriptional regulator Transcription 50120039 Common - hypothetical protein ECA1100 155 None None None 50119911 Common - hypothetical protein ECA0971 19 COG5564 COG5564, Predicted TIM-barrel enzyme, possibly a dioxygenase General function prediction only 50122271 Common - putative sigma(54) modulation protein ECA3349 92 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 50120615 Common - hypothetical protein ECA1681 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50120559 Common traR putative conjugal transfer protein ECA1625 14 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 50120624 Common cheW purine-binding chemotaxis protein ECA1690 121 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 50120312 Common tolB translocation protein TolB ECA1373 153 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 50120384 Pathogen - hypothetical protein ECA1445 1 None None None 50122085 Common pstC phosphate ABC transporter permease protein ECA3163 224 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 50121917 Common nasE nitrate transporter permease component ECA2993 196 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50121738 Common moaD molybdopterin synthase small subunit ECA2814 44 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 50122764 Common - LysR-family transcriptional regulator ECA3843 186 COG0583 LysR, Transcriptional regulator Transcription 50120934 Common - putative protease ECA2007 23 None None None 50123170 Common - ABC transporter ATP-binding protein ECA4250 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 50119005 Common ligB NAD-dependent DNA ligase LigB ECA0043 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 50123248 Common - hypothetical protein ECA4328 59 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 50122901 Common lysC aspartate kinase III ECA3981 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 50119715 Common xerD site-specific tyrosine recombinase XerD ECA0770 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50119888 Common - TetR-family transcriptional regulator ECA0946 55 COG1309 AcrR, Transcriptional regulator Transcription 50119948 Common - ABC transporter, substrate binding protein ECA1008 215 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50122186 Common - putative signaling membrane protein ECA3264 159 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 50120957 Common narX nitrate/nitrite sensor protein NarX ECA2029 148 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 50121844 Pathogen - hypothetical protein ECA2920 1 None None None 50122797 Common ileS isoleucyl-tRNA synthetase ECA3876 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50121208 Common rnfG electron transport complex protein RnfG ECA2280 57 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 50121397 Common cspG cold shock protein ECA2471 180 COG1278 CspC, Cold shock proteins Transcription 50120169 Common hybE hydrogenase 2-specific chaperone ECA1230 22 None None None 50120833 Common - hypothetical protein ECA1903 171 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120915 Common - putative peptidase ECA1988 108 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 50122823 Common - methyl-accepting chemotaxis protein ECA3902 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50122866 Common - hypothetical protein ECA3946 3 None None None 50120778 Common aglA PTS system, alpha-glucoside-specific IIBC component ECA1848 52 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50120086 Common tig trigger factor ECA1147 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 50120058 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase ECA1119 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 50120583 Pathogen - hypothetical protein ECA1651 1 None None None 50121979 Common accD acetyl-CoA carboxylase subunit beta ECA3056 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 50121559 Pathogen - phage-related hypothetical protein ECA2634 2 None None None 50119745 Common - hypothetical protein ECA0800 21 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50119566 Common - hypothetical protein ECA0616 89 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50122589 Common - AsnC-family transcriptional regulator ECA3668 149 COG1522 Lrp, Transcriptional regulators Transcription 50121720 Common - hypothetical protein ECA2796 7 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 50120124 Common - hypothetical protein ECA1185 3 None None None 50122322 Pathogen - hypothetical protein ECA3398 1 None None None 50123019 Common mrcA peptidoglycan synthetase ECA4099 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 50121181 Common - hypothetical protein ECA2253 11 None None None 50122241 Common pcnB poly(A) polymerase I ECA3319 206 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 50121100 Pathogen - hypothetical protein ECA2172 1 None None None 50119649 Pathogen - hypothetical protein ECA0701 1 None None None 50122888 Common poxA lysyl-tRNA synthetase ECA3968 219 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 50122603 Common - hypothetical protein ECA3682 18 None None None 50119966 Common - flavodoxin ECA1026 71 COG0716 FldA, Flavodoxins Energy production and conversion 50121417 Common ruvA Holliday junction DNA helicase motor protein ECA2492 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 50122100 Common - putative arabinogalactan endo-1,4-beta-galactosidase ECA3178 21 COG3867 COG3867, Arabinogalactan endo-1,4-beta-galactosidase Carbohydrate transport and metabolism 50119235 Common - hypothetical protein ECA0275 4 None None None 50122395 Common - hypothetical protein ECA3472 77 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 50119095 Common - putative peptidase ECA0134 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50119522 Common - putative plasmid-related protein ECA0573 24 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 50122316 Common - hypothetical protein ECA3392 7 None None None 50120162 Common - putative ABC transporter ATP-binding protein ECA1223 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 50119371 Common - hypothetical protein ECA0420 58 COG2850 COG2850, Uncharacterized conserved protein Function unknown 50120696 Common - hypothetical protein ECA1763 119 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 50121163 Common - putative short-chain dehydrogenase (partial) ECA2235A 16 None None None 50119050 Common mtlR mannitol repressor protein ECA0089 18 COG3722 MtlR, Transcriptional regulator Transcription 50120006 Common - hypothetical protein ECA1066 6 None None None 50120094 Common - queuosine biosynthesis protein QueC ECA1155 175 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 50122021 Common outO type 4 prepilin-like proteins leader peptide processing enzyme ECA3098 107 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 50119865 Common - hypothetical protein ECA0923 95 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50119486 Common pilQ putative Type IV pilus nucleotide-binding protein ECA0538 149 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 50123071 Common glgB glycogen branching enzyme ECA4151 151 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 50119906 Common - transcriptional regulator ECA0966 24 COG3423 Nlp, Predicted transcriptional regulator Transcription 50121809 Common cycA D-alanine/D-serine/glycine permease ECA2885 126 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 50121301 Common - outer membrane lipoprotein ECA2373 30 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 50119922 Common - putative lipoprotein ECA0982 13 None None None 50120317 Common nadA quinolinate synthetase ECA1378 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 50120962 Common narI respiratory nitrate reductase 1 gamma chain ECA2034 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 50119524 Pathogen - hypothetical protein ECA0575 1 None None None 50121189 Common tus DNA replication terminus site-binding protein ECA2261 14 None None None 50122477 Common - LysR-family transcriptional regulator ECA3556 106 COG0583 LysR, Transcriptional regulator Transcription 50120286 Common - ABC transporter ATP-binding protein ECA1347 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50121718 Common - hypothetical protein ECA2794 14 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 50120067 Common nusB transcription antitermination protein NusB ECA1128 200 COG0781 NusB, Transcription termination factor Transcription 50119642 Common dacD D-alanyl-D-alanine carboxypeptidase/endopeptidase ECA0694 109 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 50120356 Common wza putative polysaccharide export protein ECA1417 124 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 50119964 Common - hypothetical protein ECA1024 32 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 50123339 Common - ABC transporter permease protein ECA4421 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50120689 Common helD DNA helicase IV ECA1756 227 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 50121118 Common hemK N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase ECA2191 212 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 50120040 Common - multidrug transporter membrane component/ATP-binding component ECA1101 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 50121275 Common mipA MltA-interacting protein ECA2347 36 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 50120407 Common - ABC transporter, ATP-binding protein ECA1468 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50122659 Common - putative phage-related protein ECA3737 6 None None None 50121652 Common fruK 1-phosphofructokinase ECA2728 114 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 50120345 Common fdnI formate dehydrogenase-N subunit gamma ECA1406 63 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 50121997 Common - hypothetical protein ECA3074 25 COG5430 COG5430, Uncharacterized secreted protein Function unknown 50121370 Common - hypothetical protein ECA2443 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 50121726 Common - peptidase T ECA2802 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 50121424 Pathogen - hypothetical protein ECA2499 3 None None None 50121195 Common - hypothetical protein ECA2267 15 COG4875 COG4875, Uncharacterized protein conserved in bacteria with a cystatin-like fold Function unknown 50121713 Common - putative isopentenyl-diphosphate delta-isomerase ECA2789 46 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 50119111 Common coaD phosphopantetheine adenylyltransferase ECA0150 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 50122533 Common priB primosomal replication protein N ECA3612 26 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 50122340 Common - DnaG primase-like protein ECA3416 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50121564 Common - hypothetical protein ECA2640 34 COG3535 COG3535, Uncharacterized conserved protein Function unknown 50122550 Common - hypothetical protein ECA3629 102 COG0762 COG0762, Predicted integral membrane protein Function unknown 50120074 Common thiJ hypothetical protein ECA1135 73 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 50119138 Common - hypothetical protein ECA0178 3 None None None 50122352 Common - hypothetical protein ECA3428 29 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 50119217 Common cah carbonic anhydrase ECA0257 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 50119185 Common shiA shikimate transporter ECA0225 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122601 Common - hypothetical protein ECA3680 18 COG1203 COG1203, Predicted helicases General function prediction only 50119811 Common - hypothetical protein ECA0869 11 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 50119977 Common cdsA CDP-diglyceride synthase ECA1037 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 50122424 Common proW glycine betaine transporter membrane protein ECA3503 214 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 50119028 Common dsbG disulfide isomerase/thiol-disulfide oxidase ECA0066 30 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 50122002 Common fadI 3-ketoacyl-CoA thiolase ECA3079 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 50122145 Common - hypothetical protein ECA3223 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 50120825 Common napG quinol dehydrogenase periplasmic component ECA1895 56 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 50120268 Common fur ferric uptake regulator ECA1329 198 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 50122122 Common - hypothetical protein ECA3200 30 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 50123039 Common - putative acyltransferase ECA4119 42 COG3176 COG3176, Putative hemolysin General function prediction only 50120017 Common fecA iron(III) dicitrate transport protein ECA1077 96 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 50120699 Common - hypothetical protein ECA1766 16 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 50121907 Pathogen - hypothetical protein ECA2983 1 None None None 50120429 Common lacI lac repressor ECA1491 128 COG1609 PurR, Transcriptional regulators Transcription 50122874 Common - ABC transporter, ATP-binding protein ECA3954 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50119328 Common - putative pyridoxal-dependent decarboxylase ECA0369 87 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 50120956 Common narL DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) ECA2028 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50122687 Common - hypothetical protein ECA3765 28 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 50121034 Common - hypothetical protein ECA2106 19 COG3673 COG3673, Uncharacterized conserved protein Function unknown 50121621 Common ehpF putative phenazine antibiotic biosynthesis protein ECA2697 8 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 50120160 Common - short chain dehydrogenase ECA1221 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 50119731 Common - two component system sensor kinase ECA0786 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50119021 Common - TonB-like protein ECA0059 51 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 50121659 Common spr lipoprotein ECA2735 133 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 50119890 Common - hypothetical protein ECA0948 8 None None None 50123163 Common oxyR DNA-binding transcriptional regulator OxyR ECA4243 193 COG0583 LysR, Transcriptional regulator Transcription 50119772 Common - hypothetical protein ECA0829 2 None None None 50120636 Common flgB flagellar basal body rod protein FlgB ECA1702 96 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 50123049 Common - hypothetical protein ECA4129 5 None None None 50122611 Common ssb single-strand DNA-binding protein ECA3690 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 50121789 Common - hypothetical protein ECA2865 4 None None None 50122307 Pathogen - hypothetical protein ECA3383 2 None None None 50122572 Common - hypothetical protein ECA3651 38 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 50119131 Common - putative rhodanese-related sulfurtransferase ECA0171 107 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 50120418 Common - putative zinc-binding oxidoreductase ECA1480 189 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 50121153 Common - methyl-accepting chemotaxis protein ECA2226 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50119590 Common - hypothetical protein ECA0641 9 COG4287 PqaA, PhoPQ-activated pathogenicity-related protein General function prediction only 50120239 Common dacA D-alanyl-D-alanine carboxypeptidase fraction A ECA1300 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 50122580 Common - hypothetical protein ECA3659 66 COG1479 COG1479, Uncharacterized conserved protein Function unknown 50122902 Pathogen - hypothetical protein ECA3982 1 None None None 50121128 Common insG transposase for insertion sequence element IS4 (partial) ECA2202 11 None None None 50121877 Common nifT nitrogen fixation protein ECA2953 6 None None None 50119759 Common - hypothetical protein ECA0816 12 None None None 50121770 Common - hypothetical protein ECA2846 5 None None None 50122370 Common mexB multidrug resistance protein ECA3447 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 50119497 Common traE putative plasmid transfer protein ECA0548 4 None None None 50122161 Common - putative RNA methyltransferase ECA3239 157 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 50119107 Common rpmB 50S ribosomal protein L28 ECA0146 155 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 50121854 Common - HlyD-family secretion protein ECA2930 85 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50121488 Common - putative iron ABC transporter, priplasmic binding protein ECA2564 80 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 50123028 Common ompR osmolarity response regulator ECA4108 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50120657 Common fliH flagellar assembly protein H ECA1724 36 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 50121457 Common pqiA paraquat-inducible protein A ECA2533 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 50122495 Common garL alpha-dehydro-beta-deoxy-D-glucarate aldolase ECA3574 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 50123213 Common - hypothetical protein ECA4293 3 None None None 50122594 Pathogen - hypothetical protein ECA3673 3 None None None 50123010 Common dam DNA adenine methylase ECA4090 100 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 50119342 Common - hypothetical protein ECA0383 31 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 50120455 Common gltP glutamate/aspartate:proton symporter ECA1520 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 50120844 Common - ABC transporter, ATP-binding protein ECA1914 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50121109 Common - prophage integrase ECA2182 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 50120057 Common - hypothetical protein ECA1118 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 50121969 Common - hypothetical protein ECA3046 106 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 50123333 Common dgoT putative D-galactonate transporter ECA4415 200 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50121444 Common argS arginyl-tRNA synthetase ECA2520 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50119651 Pathogen - hypothetical protein ECA0704 1 None None None 50121337 Common - hypothetical protein ECA2409 38 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 50120487 Common - ABC transporter ATP-binding protein ECA1552 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121357 Common - glycerol-3-phosphate-binding periplasmic protein precursor ECA2429 93 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50121383 Common - hypothetical protein ECA2457 96 COG1881 COG1881, Phospholipid-binding protein General function prediction only 50122703 Common fepA TonB dependent siderophore receptor ECA3781 101 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 50121780 Pathogen - hypothetical protein ECA2856 2 None None None 50122379 Common - hypothetical protein ECA3456 6 None None None 50123126 Common rffG dTDP-glucose 4,6-dehydratase ECA4206 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 50118974 Common - hypothetical protein ECA0009 26 COG3111 COG3111, Uncharacterized conserved protein Function unknown 50120918 Common - murein peptide amidase A ECA1991 18 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 50119540 Pathogen - hypothetical protein ECA0590 1 None None None 50121950 Common nuoB NADH dehydrogenase subunit B ECA3027 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 50121556 Pathogen - hypothetical protein ECA2631 1 None None None 50122441 Common pssA phosphatidylserine synthase ECA3520 28 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 50121075 Common - putative ABC transport ATP-binding subunit ECA2147 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 50121946 Common nuoG NADH dehydrogenase subunit G ECA3023 186 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 50122434 Common emrB multidrug resistance protein B ECA3513 202 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122501 Pathogen - hypothetical protein ECA3580 1 None None None 50119688 Common gcvT glycine cleavage system aminomethyltransferase T ECA0743 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 50120368 Common nahM 4-hydroxy-2-ketovalerate aldolase ECA1429 204 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 50122387 Common crl DNA-binding transcriptional regulator Crl ECA3464 13 None None None 50121258 Common expM response regulator of RpoS ECA2330 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 50119801 Common - beta-glucosidase ECA0859 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50122924 Common - hypothetical protein ECA4004 16 COG3036 COG3036, Uncharacterized protein conserved in bacteria Function unknown 50120126 Common - putative carbon starvation protein ECA1187 106 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 50121990 Common - hypothetical protein ECA3067 148 COG0730 COG0730, Predicted permeases General function prediction only 50120242 Common mrdA penicillin-binding protein 2 ECA1303 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 50122286 Common - hypothetical protein ECA3364 77 COG1238 COG1238, Predicted membrane protein Function unknown 50119175 Common coaA pantothenate kinase ECA0215 72 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 50119014 Common - hypothetical protein ECA0052 90 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 50119728 Common - putative permease ECA0783 134 COG2252 COG2252, Permeases General function prediction only 50119225 Common - putative zinc-binding oxidoreductase ECA0265 116 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 50119172 Common hemG protoporphyrinogen oxidase ECA0212 37 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 50119747 Common - hypothetical protein ECA0802 31 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50122232 Common fhuB iron-hydroxamate transporter permease subunit ECA3310 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50121962 Common ackA acetate kinase ECA3039 162 COG0282 ackA, Acetate kinase Energy production and conversion 50120103 Common - putative 6-O-methylguanine DNA methyltransferase ECA1164 135 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 50119043 Common tag DNA-3-methyladenine glycosylase I ECA0082 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 50122747 Common - hypothetical protein ECA3826 13 None None None 50122762 Common - putative extracellular solute-binding protein ECA3841 100 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 50122335 Common - hypothetical protein ECA3411 3 None None None 50119752 Common - hypothetical protein ECA0807 51 COG3162 COG3162, Predicted membrane protein Function unknown 50123177 Common rpmE 50S ribosomal protein L31 ECA4257 189 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 50119421 Pathogen - hypothetical protein ECA0470 1 COG5487 COG5487, Small integral membrane protein Function unknown 50118996 Common - putative GNAT-family acetyltransferase ECA0033 43 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 50119321 Common scrA PTS system, sucrose-specific IIbc component ECA0362 43 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50119080 Common lldD L-lactate dehydrogenase ECA0119 130 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 50119859 Common rspA putative starvation sensing mandelate racemase / muconate lactonizing enzyme ECA0917 108 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50119406 Common - hypothetical protein ECA0455 5 None None None 50119118 Common waaJ lipopolysaccharide 1,2-glucosyltransferase ECA0157 31 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 50119553 Common cfa6 type I polyketide synthase ECA0603 220 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50120847 Common - putative allophanate hydrolase ECA1917 233 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 50122028 Common outH general secretion pathway protein H ECA3105 16 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 50120068 Common thiL thiamine monophosphate kinase ECA1129 200 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 50120593 Pathogen - hypothetical protein ECA1661 2 None None None 50120471 Common hasD Type I secretion ATP-binding protein ECA1536 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 50120898 Common - putative thiamine biosynthesis protein ECA1970 132 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 50121937 Common treC trehalose-6-phosphate hydrolase ECA3014 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 50120458 Common - putative glycerol dehydrogenase ECA1523 92 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 50123073 Common - hypothetical protein ECA4153 58 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 50119422 Common - hypothetical protein ECA0471 22 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 50122644 Common - conserved phage-related protein ECA3723 12 COG4388 COG4388, Mu-like prophage I protein General function prediction only 50120549 Common virB8 putative conjugal transfer protein ECA1616 29 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 50119284 Common - putative plasmid stability protein ECA0325 23 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 50119411 Common - hypothetical protein ECA0460 35 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 50120621 Common motA flagellar motor protein MotA ECA1687 107 COG1291 MotA, Flagellar motor component Cell motility and secretion 50120061 Common secD preprotein translocase subunit SecD ECA1122 223 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 50123235 Common - putative RNA-methyltransferase ECA4315 161 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 50119636 Common - hypothetical protein ECA0688 11 None None None 50119165 Common ubiD 3-octaprenyl-4-hydroxybenzoate decarboxylase ECA0205 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 50122754 Common leuC isopropylmalate isomerase large subunit ECA3833 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 50122400 Common - putative translation initiation factor EIF-2B ECA3477 131 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 50122851 Common hflC FtsH protease regulator HflC ECA3931 156 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 50121375 Common pepT peptidase T ECA2448 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 50121870 Common nifU nitrogen fixation protein ECA2946 141 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 50123232 Common cpxA two-component sensor protein ECA4312 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50121493 Common citG 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase ECA2569 48 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 50122835 Common tktA2 transketolase ECA3914 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 50120679 Common betA choline dehydrogenase ECA1746 91 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 50119416 Common serB phosphoserine phosphatase ECA0465 149 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 50122893 Common blc outer membrane lipoprotein Blc ECA3973 69 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 50121390 Common yebU rRNA (cytosine-C(5)-)-methyltransferase RsmF ECA2464 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 50120748 Common - probable transporter ECA1817 117 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120259 Common ubiF 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase ECA1320 132 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 50120963 Common pecM regulatory protein ECA2035 177 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 50119606 Common - periplasmic protein ECA0658 15 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 50121758 Common - putative ABC transporter periplasmic binding protein ECA2834 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50120541 Pathogen mobC mobilization protein ECA1608 5 None None None 50121027 Pathogen hrpG type III secretion protein ECA2099 1 None None None 50122674 Common - hypothetical protein ECA3752 16 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 50119469 Pathogen - hypothetical protein ECA0518 2 None None None 50119442 Common phnH carbon-phosphorus lyase complex subunit ECA0491 34 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 50121068 Common - putative oxidoreductase ECA2140 80 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50122858 Common - putative ATPase ECA3938 207 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 50119578 Common dgkA diacylglycerol kinase ECA0629 69 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 50123324 Common - hypothetical protein ECA4406 10 None None None 50119515 Common - hypothetical protein ECA0566 17 None None None 50121773 Common - metallo-beta-lactamase ECA2849 92 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 50122466 Common cysH phosphoadenosine phosphosulfate reductase ECA3545 152 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 50119072 Common - hypothetical protein ECA0111 39 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 50119932 Pathogen ppdC putative prepilin peptidase dependent protein c precursor ECA0992 2 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 50122971 Common - putative transcriptional regulator ECA4051 140 COG1733 COG1733, Predicted transcriptional regulators Transcription 50119901 Common - putative acetyltransferase ECA0959 40 COG3153 COG3153, Predicted acetyltransferase General function prediction only 50122095 Common lamB maltoporin ECA3173 25 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 50120113 Common - hypothetical protein ECA1174 32 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 50120702 Common - hypothetical protein ECA1769 97 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 50121708 Common inh protease inhibitor ECA2784 4 None None None 50119574 Common groEL chaperonin GroEL ECA0625 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 50120532 Common - hypothetical protein ECA1598 20 None None None 50121114 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ECA2187 192 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 50122739 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase ECA3817 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 50119234 Common - hypothetical protein ECA0274 5 None None None 50120023 Common mltB membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan ECA1083 105 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 50119873 Common - putative avirulence protein ECA0931 5 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 50120605 Pathogen - hypothetical protein ECA1672 1 None None None 50120890 Common - putative oxidoreductase ECA1962 189 COG4989 COG4989, Predicted oxidoreductase General function prediction only 50119331 Common - hypothetical protein ECA0372 20 COG3787 COG3787, Uncharacterized protein conserved in bacteria Function unknown 50120862 Common pcp outer membrane lipoprotein ECA1932 25 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 50122805 Common - putative transport protein ECA3884 148 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119713 Pathogen - hypothetical protein ECA0768 1 None None None 50120422 Common - hypothetical protein ECA1484 12 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 50119292 Common icc cyclic 3',5'-adenosine monophosphate phosphodiesterase ECA0333 82 COG1409 Icc, Predicted phosphohydrolases General function prediction only 50119155 Common rmuC DNA recombination protein ECA0195 147 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 50122455 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ECA3534 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 50119777 Common - hypothetical protein ECA0834 6 None None None 50121682 Common - hypothetical protein ECA2758 33 COG3668 ParE, Plasmid stabilization system protein General function prediction only 50121923 Common cydB2 cytochrome D ubiquinol oxidase subunit II ECA2999 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 50123151 Common - hypothetical protein ECA4231 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 50119061 Common xylH xylose transport system permease ECA0100 147 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 50120322 Common cusA cation efflux system protein ECA1383 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 50119194 Common rsd anti-RNA polymerase sigma 70 factor ECA0233 24 COG3160 Rsd, Regulator of sigma D Transcription 50120707 Common - methyl-accepting chemotaxis protein ECA1774 160 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120577 Common - hypothetical protein ECA1645 3 None None None 50122559 Common ecnA entericidin A precursor ECA3638 7 COG5510 COG5510, Predicted small secreted protein Function unknown 50122561 Common - hypothetical protein ECA3640 79 None None None 50121532 Common - probable bacteriophage variable tail fiber protein H ECA2608 30 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 50122972 Common - hypothetical protein ECA4052 25 None None None 50119825 Common cysP thiosulfate transporter subunit ECA0883 88 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 50121251 Common oppB oligopeptide transporter permease ECA2323 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121677 Pathogen - putative phage-related protein ECA2753 2 None None None 50121689 Common - threonine and homoserine efflux system ECA2765 79 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 50119702 Common - hypothetical protein ECA0757 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 50120510 Pathogen - hypothetical protein ECA1576 1 None None None 50122273 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase ECA3351 75 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 50122729 Common secM SecA regulator SecM ECA3807 11 None None None 50119806 Pathogen - hypothetical protein ECA0864 1 None None None 50121475 Common - hypothetical protein ECA2551 83 COG1434 COG1434, Uncharacterized conserved protein Function unknown 50121017 Common hrpY two-component response regulator ECA2089 216 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50119435 Pathogen - hypothetical protein ECA0484 1 None None None 50120127 Common - hypothetical protein ECA1188 26 COG2879 COG2879, Uncharacterized small protein Function unknown 50120497 Common - TetR-family transcriptional regulator ECA1562 118 COG1309 AcrR, Transcriptional regulator Transcription 50122443 Common kgtP alpha-ketoglutarate transporter ECA3522 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119897 Common - LysR-family transcriptional regulator ECA0955 169 COG0583 LysR, Transcriptional regulator Transcription 50121260 Common - hypothetical protein ECA2332 88 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 50121241 Common ispZ intracellular septation protein A ECA2313 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 50122651 Common - major tail sheath protein ECA3730 23 COG3498 COG3498, Phage tail tube protein FII General function prediction only 50120303 Common sucD succinyl-CoA synthetase subunit alpha ECA1364 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 50119812 Common - putative transcriptional regulator ECA0870 69 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 50120539 Common arsH arsenical resistance protein ECA1606 64 COG0431 COG0431, Predicted flavoprotein General function prediction only 50119740 Common - hypothetical protein ECA0795 17 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 50119878 Common - putative glucarate dehydratase ECA0936 38 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50121050 Pathogen - probable integrase/recombinase (partial) ECA2122 2 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50121474 Common smtA putative metallothionein SmtA ECA2550 68 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 50120731 Common acpP acyl carrier protein ECA1798 179 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50121611 Common - ABC transporter integral membrane protein ECA2687 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 50118991 Common glnL nitrogen regulation protein NR(II) ECA0028 210 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 50121096 Common - hypothetical protein ECA2168 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 50120229 Common - putative D-alanyl-D-alanine carboxypeptidase ECA1290 28 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 50123255 Common - methyl-accepting chemotaxis protein ECA4335 108 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50122065 Common arnT 4-amino-4-deoxy-L-arabinose transferase ECA3142 92 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 50121748 Common bioF 8-amino-7-oxononanoate synthase ECA2824 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 50122896 Common efp elongation factor P ECA3976 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 50120263 Common nagC N-acetylglucosamine repressor ECA1324 163 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 50122315 Common - putative prophage regulatory ptotein ECA3391 48 COG1476 COG1476, Predicted transcriptional regulators Transcription 50119818 Common iutA TonB-dependent ferric aerobactin receptor ECA0876 53 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50121515 Common rpsA 30S ribosomal protein S1 ECA2591 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 50121015 Common hrpL sigma factor ECA2087 156 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50122841 Common sprT hypothetical protein ECA3921 26 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 50120644 Common flgJ peptidoglycan hydrolase ECA1710 75 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 50123412 Common - hypothetical protein ECA4496 33 COG4258 COG4258, Predicted exporter General function prediction only 50122268 Common - hypothetical protein ECA3346 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 50121545 Common - phage terminase, endonuclease small subunit M ECA2620 16 None None None 50123362 Common rnpA ribonuclease P ECA4444 69 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 50119432 Common entA 2,3-dihydroxybenzoate-2,3-dehydrogenase ECA0481 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50119626 Pathogen - putative phage regulatory protein ECA0678 1 None None None 50122815 Common creA hypothetical protein ECA3894 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 50120415 Common - hypothetical protein ECA1477 5 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 50121500 Common citW citrate/acetate antiporter ECA2576 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 50120089 Common lon DNA-binding ATP-dependent protease La ECA1150 219 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 50119492 Common pilV putative Type IV pilus prepilin protein ECA0544 10 None None None 50122192 Common - hypothetical protein ECA3270 190 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50121297 Common minD cell division inhibitor MinD ECA2369 144 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 50119845 Common norR anaerobic nitric oxide reductase transcription regulator ECA0903 168 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 50120986 Common - probable short-chain dehydrogenase ECA2058 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50122261 Common dnaQ DNA polymerase III subunit epsilon ECA3339 182 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 50122720 Common ppdD putative major pilin subunit ECA3798 20 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 50122465 Common cysG1 siroheme synthase [includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase] ECA3544 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 50123042 Common tex putative RNA binding protein ECA4122 215 COG2183 Tex, Transcriptional accessory protein Transcription 50121412 Common - LacI-family transcriptional regulator ECA2487 119 COG1609 PurR, Transcriptional regulators Transcription 50122669 Common - ABC transporter, membrane spanning protein ECA3747 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 50119952 Common csdA cysteine sulfinate desulfinase ECA1012 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 50120690 Common mgsA methylglyoxal synthase ECA1757 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 50121207 Common rnfD electron transport complex protein RnfD ECA2279 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 50122480 Common rhiN plant-inducible protein ECA3559 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 50119368 Common - putative kinase ECA0410 15 COG0645 COG0645, Predicted kinase General function prediction only 50119625 Pathogen - putative phage regulatory protein ECA0677 1 None None None 50121198 Common araC DNA-binding transcriptional regulator AraC ECA2270 126 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50120064 Common - hypothetical protein ECA1125 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 50120274 Common seqA replication initiation regulator SeqA ECA1335 23 COG3057 SeqA, Negative regulator of replication initiationR DNA replication, recombination, and repair 50120390 Common - probable glycosyl hydrolase ECA1451 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50120910 Common pspA phage shock protein A ECA1983 82 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 50119019 Common - ECF-family RNA polymerase sigma factor ECA0057 89 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50121204 Common rnfA Na(+)-translocating NADH-quinone reductase subunit E ECA2276 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 50123062 Common - putative RHS accessory genetic element ECA4142 60 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 50123358 Common dnaN DNA polymerase III subunit beta ECA4440 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 50119917 Common trmB tRNA (guanine-N(7))-methyltransferase ECA0977 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 50123422 Common - hypothetical protein ECA4506 34 None None None 50120585 Common - transposase ECA1653 62 None None None 50119263 Common degQ exported protease ECA0303 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 50122157 Common iscA iron-sulfur cluster assembly protein ECA3235 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 50120387 Common - hypothetical protein ECA1448 22 None None None 50120284 Common - ABC transporter permease protein ECA1345 125 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 50121830 Pathogen - hypothetical protein ECA2906 1 None None None 50119392 Common rhaS L-rhamnose operon regulatory protein ECA0441 38 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 50120256 Common - hypothetical protein ECA1317 192 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 50119968 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase ECA1028 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 50120596 Common - putative lipoprotein ECA1664 2 None None None 50122184 Common murQ N-acetylmuramic acid-6-phosphate etherase ECA3262 87 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 50120633 Common flgN flagella synthesis protein ECA1699 14 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 50119266 Common rplM 50S ribosomal protein L13 ECA0306 239 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 50122035 Common - pectate lyase ECA3112 19 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 50122109 Common mdtD multidrug efflux system protein MdtE ECA3187 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119584 Common - hypothetical protein ECA0635 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50121183 Common - hypothetical protein ECA2255 13 None None None 50122884 Common orn oligoribonuclease ECA3964 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 50121688 Common ompX outer membrane protein X ECA2764 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 50122229 Common hemL glutamate-1-semialdehyde aminotransferase ECA3307 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 50120611 Common chpR suppressor of growth inhibitory protein ChpA ECA1677 16 COG2336 MazE, Growth regulator Signal transduction mechanisms 50121697 Common - bacteriophage tail sheath protein (partial) ECA2773 11 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 50120613 Common intB phage integrase ECA1679 102 COG0582 XerC, Integrase DNA replication, recombination, and repair 50121514 Common ihfB integration host factor subunit beta ECA2590 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 50120929 Common aer2 aerotaxis receptor ECA2002 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50123064 Common - hypothetical protein ECA4144 2 None None None 50122824 Common - LysR-family transcriptional activator ECA3903 156 COG0583 LysR, Transcriptional regulator Transcription 50122293 Common - hypothetical protein ECA3371 6 None None None 50121919 Common nasR nitrate-and nitrite-responsive positive regulator ECA2995 74 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 50122869 Pathogen - hypothetical protein ECA3949 1 None None None 50120665 Common - hypothetical protein ECA1732 66 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 50119848 Common - hypothetical protein ECA0906 41 COG4125 COG4125, Predicted membrane protein Function unknown 50121484 Common - hypothetical protein ECA2560 22 COG2926 COG2926, Uncharacterized protein conserved in bacteria Function unknown 50120917 Common tpx thiol peroxidase ECA1990 110 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 50122523 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein ECA3602 125 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 50121701 Common - hypothetical protein ECA2777 9 None None None 50121480 Common lpxK tetraacyldisaccharide 4'-kinase ECA2556 124 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 50119124 Common waaC ADP-heptose:LPS heptosyl transferase I ECA0163 93 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 50122023 Common outM general secretion pathway protein M ECA3100 18 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 50120170 Common hypE hydrogenase isoenzyme formation protein ECA1231 135 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 50119453 Common - putative capsulatr polysaccharide biosynthesis protein ECA0502 118 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 50119277 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase ECA0317 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 50120092 Common - hypothetical protein ECA1153 79 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 50122172 Common glyA serine hydroxymethyltransferase ECA3250 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 50120854 Common cfa cyclopropane fatty acyl phospholipid synthase ECA1924 136 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 50122231 Common - hypothetical protein ECA3309 81 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50123023 Common - putative hydrolase ECA4103 36 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 50122673 Common - extracellular solute-binding protein ECA3751 21 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50119695 Common - putative calcineurin-like phosphoesterase ECA0750 99 COG1409 Icc, Predicted phosphohydrolases General function prediction only 50122938 Common rpsN 30S ribosomal protein S14 ECA4018 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 50120372 Common - putative acyl transferase ECA1433 97 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 50122829 Common - hypothetical protein ECA3908 77 COG2968 COG2968, Uncharacterized conserved protein Function unknown 50120512 Common - hypothetical protein ECA1578 30 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 50122247 Common - ABC transporter ATP-binding protein ECA3325 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 50121471 Common mukB cell division protein MukB ECA2547 34 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 50122863 Common - hypothetical protein ECA3943 20 None None None 50119580 Common - putative stress-response protein ECA0631 54 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 50120464 Common tauC putative taurine transport system permease protein ECA1529 199 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50122283 Common - hypothetical protein ECA3361 85 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 50122338 Pathogen - hypothetical protein ECA3414 1 None None None 50122007 Common - hypothetical protein ECA3084 56 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 50121755 Common sfcA NAD-dependent malic enzyme ECA2831 199 COG0281 SfcA, Malic enzyme Energy production and conversion 50122152 Common pepB aminopeptidase B ECA3230 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 50122980 Common - predicted hydrolase ECA4060 71 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 50121347 Common rplT 50S ribosomal protein L20 ECA2419 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 50121807 Common - hypothetical protein ECA2883 10 None None None 50123399 Common nac nitrogen assimilation transcriptional regulator ECA4483 183 COG0583 LysR, Transcriptional regulator Transcription 50122478 Common - metallo hydrolase ECA3557 98 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 50122804 Common - hypothetical protein ECA3883 52 COG1584 COG1584, Predicted membrane protein Function unknown 50122001 Common fadJ multifunctional fatty acid oxidation complex subunit alpha ECA3078 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 50123436 Common gidB glucose-inhibited division protein B ECA4520 201 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 50121620 Common ehpG putative phenazine antibiotic biosynthesis protein ECA2696 36 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50119505 Common - hypothetical protein ECA0556 40 None None None 50122087 Common ppx exopolyphosphatase ECA3165 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 50119530 Pathogen - hypothetical protein ECA0581 3 None None None 50121137 Common - copper-zinc superoxide dismutase ECA2211 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 50120225 Common - hypothetical protein ECA1286 35 None None None 50119399 Common - putative ABC transporter extracellular solute binding protein ECA0448 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50121120 Common sirB1 putative transcriptional regulator ECA2193 54 COG2912 COG2912, Uncharacterized conserved protein Function unknown 50119097 Common - ABC transporter permease protein ECA0136 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122903 Common - putative sodium/phosphate cotransporter ECA3983 85 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 50122224 Common dgt deoxyguanosinetriphosphate triphosphohydrolase ECA3302 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 50121461 Common - hypothetical protein ECA2537 17 None None None 50119188 Common thiH thiamine biosynthesis protein ThiH ECA0228 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 50120627 Common cheB chemotaxis-specific methylesterase ECA1693 207 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 50121306 Common pabB para-aminobenzoate synthase component I ECA2378 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 50119516 Common - hypothetical protein ECA0567 8 None None None 50122547 Common - putative type II/IV secretion system protein ECA3626 224 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 50121883 Pathogen - hypothetical protein ECA2959 3 None None None 50121083 Common - putative acetyltransferase ECA2155 36 COG3393 COG3393, Predicted acetyltransferase General function prediction only 50119025 Common - hypothetical protein ECA0063 25 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 50119196 Common hemE uroporphyrinogen decarboxylase ECA0235 182 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 50120406 Common - hypothetical protein ECA1467 11 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 50121450 Common grxB glutaredoxin 2 ECA2526 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 50121557 Common - hypothetical protein ECA2632 6 None None None 50122240 Common - glutamyl-Q tRNA(Asp) synthetase ECA3318 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 50119862 Common - probable carbohydrate oxidoreductase ECA0920 91 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 50122277 Common - hypothetical protein ECA3355 7 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 50120714 Common - hypothetical protein ECA1781 121 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 50121158 Common - hypothetical protein ECA2231 65 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 50121764 Common - hypothetical protein ECA2840 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50121629 Common ehpR putative phenazine antibiotic biosynthesis protein ECA2705 21 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 50120946 Pathogen - hypothetical protein ECA2019 1 None None None 50121572 Common lrp leucine-responsive transcriptional regulator ECA2648 157 COG1522 Lrp, Transcriptional regulators Transcription 50121842 Common - putative phage-related protein ECA2918 37 COG3311 AlpA, Predicted transcriptional regulator Transcription 50121921 Common - bacteriophage tail fiber assembly protein ECA2997 8 None None None 50121998 Common - putative fimbrial chaperone ECA3075 25 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 50119377 Common aspA1 aspartate ammonia-lyase ECA0426 211 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 50121636 Common - putative methyl-accepting chemotaxis protein ECA2712 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120932 Common acpD azoreductase ECA2005 99 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 50120008 Pathogen - hypothetical protein ECA1068 4 None None None 50122181 Common - putative transglycosylase ECA3259 95 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 50122083 Common pstB phosphate ABC transporter ATP-binding protein ECA3161 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 50121274 Common - putative aldo/keto reductase ECA2346 195 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 50123378 Common aegA putative oxidoreductase Fe-S binding subunit ECA4461 212 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 50122912 Common metA homoserine O-succinyltransferase ECA3992 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 50119444 Common phnJ putative phosphonate metabolism protein ECA0493 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 50122623 Pathogen - hypothetical phage-related protein ECA3702 1 None None None 50122362 Common - putative lipoprotein ECA3439 18 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 50121631 Pathogen - hypothetical protein ECA2707 1 None None None 50119203 Common aapM L-amino acid ABC transporter permease protein ECA0243 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50119941 Common mltA murein transglycosylase A ECA1001 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 50123365 Common - hypothetical protein ECA4447 3 None None None 50119110 Common - putative sugar transferase ECA0149 59 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 50119793 Common - putative sugar ABC transporter, permease protein ECA0850 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 50120922 Common - C32 tRNA thiolase ECA1995 163 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 50119007 Common - putative virulence-associated outer membrane protein ECA0045 12 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 50121732 Common cbrB achromobactin transport system permease protein ECA2808 187 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50119404 Pathogen - hypothetical protein ECA0453 1 None None None 50123199 Pathogen - hypothetical protein ECA4279 2 None None None 50120966 Common - hypothetical protein ECA2038 53 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 50122574 Common lysR DNA-binding transcriptional regulator LysR ECA3653 181 COG0583 LysR, Transcriptional regulator Transcription 50120203 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase ECA1264 211 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 50120764 Common btuD vitamin B12-transporter ATPase ECA1834 249 COG4138 BtuD, ABC-type cobalamin transport system, ATPase component Coenzyme metabolism 50121975 Common purF amidophosphoribosyltransferase ECA3052 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 50120906 Common - LysR-family transcriptional regulator ECA1978 172 COG0583 LysR, Transcriptional regulator Transcription 50119560 Common - LysR-family transcriptional regulator ECA0610 126 COG0583 LysR, Transcriptional regulator Transcription 50121899 Common - hypothetical protein ECA2975 8 COG5504 COG5504, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 50123145 Common ilvA threonine dehydratase ECA4225 203 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 50119671 Pathogen - hypothetical protein ECA0726 1 None None None 50120249 Common - hypothetical protein ECA1310 20 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 50123182 Common hslU ATP-dependent protease ATP-binding subunit ECA4262 210 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 50119986 Common dnaE DNA polymerase III subunit alpha ECA1046 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 50121839 Pathogen - hypothetical protein ECA2915 2 None None None 50123212 Common xerC site-specific tyrosine recombinase XerC ECA4292 222 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50121582 Pathogen - hypothetical protein ECA2658 1 None None None 50123428 Common atpD F0F1 ATP synthase subunit beta ECA4512 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 50120434 Common uhpB two-component system sensor histidine kinase ECA1496 135 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 50121890 Common - putative extracellular solute-binding protein ECA2966 123 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50121987 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase ECA3064 85 COG4121 COG4121, Uncharacterized conserved protein Function unknown 50122570 Common - transcriptional repressor of carbon metabolism ECA3649 129 COG1609 PurR, Transcriptional regulators Transcription 50120498 Common - putative lipoprotein ECA1563 17 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 50122131 Common guaB inositol-5-monophosphate dehydrogenase ECA3209 234 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 50120441 Common - hypothetical protein ECA1505 35 COG1802 GntR, Transcriptional regulators Transcription 50120883 Common - hypothetical protein ECA1955 21 COG3771 COG3771, Predicted membrane protein Function unknown 50123094 Common - hypothetical protein ECA4174 38 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 50121821 Common - hypothetical protein ECA2897 8 None None None 50121227 Common trpC bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase ECA2299 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 50121579 Common - hypothetical protein ECA2655 78 COG2128 COG2128, Uncharacterized conserved protein Function unknown 50120503 Common - putative chemotaxis signal transduction protein ECA1568 150 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 50119836 Common cysK cysteine synthase A ECA0894 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 50122490 Common relA GDP/GTP pyrophosphokinase ECA3569 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 50120907 Common - short chain dehydrogenase ECA1979 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 50120899 Common aidA hypothetical protein ECA1971 6 None None None 50122881 Common - hypothetical protein ECA3961 10 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 50119354 Pathogen - hypothetical protein ECA0397 2 None None None 50123387 Common benE putative benzoate transport protein ECA4471 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 50119677 Common - hypothetical protein ECA0732 8 None None None 50120873 Common ribA GTP cyclohydrolase II ECA1943 187 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 50121240 Pathogen - hypothetical protein ECA2312 4 None None None 50119881 Common - putative fimbrial protein ECA0939 13 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 50123256 Common - putative aminotransferase ECA4336 228 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50121061 Pathogen - hypothetical protein ECA2133 1 None None None 50121076 Common - putative ABC transport ATP-binding subunit ECA2148 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 50122257 Common nrdH putative glutaredoxin ECA3335 33 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 50121468 Common - putative metallo-beta-lactamase ECA2544 220 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 50123175 Common - putative iron(III) ABC transporter, periplasmic-binding protein ECA4255 91 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50120403 Common mocC putative myo-inositol catabolism protein ECA1464 74 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 50122770 Common ilvN acetolactate synthase 1 regulatory subunit ECA3849 87 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 50121334 Common togB periplasmic pectic oligomers binding protein ECA2406 74 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50122112 Common sat streptogramin A acetyl transferase ECA3190 154 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 50123307 Common - beta-glucoside operon antiterminator ECA4389 29 COG3711 BglG, Transcriptional antiterminator Transcription 50119614 Pathogen - hypothetical protein ECA0666 1 None None None 50121589 Common - putative N-acetylmuramoyl-L-alanine amidase ECA2665 84 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 50120719 Common dinI DNA damage-inducible protein I ECA1786 13 None None None 50122987 Common pelA pectate lyase I ECA4067 14 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 50120600 Common - putative type IV prepilin ECA1668 20 None None None 50122731 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase ECA3809 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 50122968 Common - GntR-family transcriptional regulator ECA4048 209 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50120960 Common narH respiratory nitrate reductase 1 beta chain ECA2032 149 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 50119087 Common - hypothetical protein ECA0126 16 None None None 50120260 Pathogen - hypothetical protein ECA1321 2 None None None 50123343 Common - putative dihydrodipicolinate synthetase ECA4425 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 50122596 Common - hypothetical protein ECA3675 9 None None None 50121590 Common - hypothetical protein ECA2666 99 COG0393 COG0393, Uncharacterized conserved protein Function unknown 50123262 Common - putative acetyltransferase ECA4342 12 None None None 50122062 Common sfuC iron(III)-transport ATP-binding protein ECA3139 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50122072 Common folD bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase ECA3149 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 50123092 Common recQ ATP-dependent DNA helicase RecQ ECA4172 238 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 50120164 Common hybO hydrogenase 2 small subunit ECA1225 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 50119147 Common ppc phosphoenolpyruvate carboxylase ECA0187 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 50122740 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase ECA3818 225 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 50121395 Common - hypothetical protein ECA2469 8 None None None 50121535 Common - phage baseplate assembly protein W ECA2611 29 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 50121523 Common - bacteriophage regulatory protein ECA2599 6 None None None 50122704 Pathogen - hypothetical protein ECA3782 1 None None None 50120795 Common - hypothetical protein ECA1865 84 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 50121910 Common - probable oxidase ECA2986 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 50123266 Common ftsY cell division protein FtsY ECA4346 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 50122779 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase ECA3858 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 50118973 Common qseB two-component system response regulator. ECA0008 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50120975 Common - hypothetical protein ECA2047 49 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 50121095 Common - putative inositol monophosphatase ECA2167 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 50121546 Common - major phage capsid protein N precursor ECA2621 22 None None None 50121538 Common - phage tail completion protein R ECA2614 17 None None None 50121615 Common - hypothetical protein ECA2691 117 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 50119334 Common nrdD anaerobic ribonucleoside triphosphate reductase ECA0375 98 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 50119592 Common exuR DNA-binding transcriptional repressor ExuR ECA0643 142 COG2186 FadR, Transcriptional regulators Transcription 50121606 Common - hypothetical protein ECA2682 8 None None None 50122618 Pathogen - hypothetical protein ECA3697 2 None None None 50121681 Common - hypothetical protein ECA2757 15 COG3905 COG3905, Predicted transcriptional regulator Transcription 50119876 Common - putative acetyltransferase ECA0934 32 COG0456 RimI, Acetyltransferases General function prediction only 50122931 Common secY preprotein translocase subunit SecY ECA4011 228 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 50119132 Common secB preprotein translocase subunit SecB ECA0172 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 50120786 Common - putative FAD-binding oxidase ECA1856 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 50121113 Common prs ribose-phosphate pyrophosphokinase ECA2186 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 50120808 Common nrfD nitrite reductase complex component ECA1878 35 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 50121980 Common dedA hypothetical protein ECA3057 168 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 50122994 Common - ABC transporter permease protein ECA4074 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50119139 Common - hypothetical protein ECA0179 53 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 50121612 Common - ABC transporter ATP-binding protein ECA2688 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 50122076 Common ppiB peptidyl-prolyl cis-trans isomerase B (rotamase B) ECA3154 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 50120149 Common menF menaquinone-specific isochorismate synthase ECA1210 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50120698 Pathogen - hypothetical protein ECA1765 1 None None None 50123099 Common uvrD DNA-dependent helicase II ECA4179 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 50119824 Common - hypothetical protein ECA0882 49 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 50122943 Common rpmC 50S ribosomal subunit protein L29 ECA4023 149 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 50123003 Common occM octopine transport system permease protein ECA4083 173 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 50120177 Common hyfJ hydrogenase-4 component J ECA1238 13 None None None 50119221 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit ECA0261 190 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 50123317 Common dcuS sensory histidine kinase DcuS ECA4399 203 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 50119786 Common mntH manganese transport protein MntH ECA0843 106 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 50120562 Pathogen - hypothetical protein ECA1628 3 None None None 50121233 Common - hypothetical protein ECA2305 15 None None None 50121006 Common hrcS type III secretion protein ECA2078 20 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 50122849 Common purA adenylosuccinate synthetase ECA3929 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 161501870 Common tbpA thiamin transporter substrate binding subunit ECA3844 79 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 50123152 Common hdfR transcriptional regulator HdfR ECA4232 186 COG0583 LysR, Transcriptional regulator Transcription 50120321 Common gpmA phosphoglyceromutase ECA1382 163 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 50119605 Pathogen - hypothetical protein ECA0656 2 None None None 50121742 Common - hypothetical protein ECA2818 86 COG0391 COG0391, Uncharacterized conserved protein Function unknown 50122813 Common - putative RNA methyltransferase ECA3892 152 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 50120969 Common - putative DNA-binding protein ECA2041 50 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 50119248 Common rpoN RNA polymerase factor sigma-54 ECA0288 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 161501885 Common - hypothetical protein ECA0108 16 COG3136 GlpM, Uncharacterized membrane protein required for alginate biosynthesis General function prediction only 50120145 Common - probable transcriptional regulator ECA1206 133 COG1733 COG1733, Predicted transcriptional regulators Transcription 50120212 Common - putative sensor protein ECA1273 43 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 50120347 Common fdnG formate dehydrogenase, nitrate-inducible, major subunit ECA1408 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 50121793 Common rhs putative RHS protein ECA2869 68 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 50120394 Common - putative transcriptional regulator ECA1455 100 COG1737 RpiR, Transcriptional regulators Transcription 50122320 Pathogen - hypothetical protein ECA3396 1 None None None 50123236 Pathogen - hypothetical protein ECA4316 1 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 50122414 Common - putative amino acid ABC transporter, permease protein ECA3493 170 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50122693 Common - putative multidrug resistance protein ECA3771 133 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 50121982 Common - hypothetical protein ECA3059 199 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 50118984 Common - predicted kinase ECA0019 52 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 50121865 Common nifM nitrogen fixation protein ECA2941 87 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 50120484 Common - putative ABC transporter substrate-binding protein ECA1549 84 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50121004 Common hrcU type III secretion protein ECA2076 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 50119660 Common rbfA ribosome-binding factor A ECA0713 168 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 50122961 Common dsrE hypothetical protein ECA4041 43 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 50122840 Common metK S-adenosylmethionine synthetase ECA3920 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 50121422 Common - putative signal transduction protein ECA2497 55 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 50123169 Common - ABC transporter periplasmic binding protein ECA4249 23 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 50119215 Common fis DNA-binding protein Fis ECA0255 98 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 50119447 Common phnM putative phosphonate metabolism protein ECA0496 52 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 50123432 Common atpF F0F1 ATP synthase subunit B ECA4516 93 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 50122393 Common - putative methyltransferase ECA3470 142 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50122445 Common metN DL-methionine transporter ATP-binding subunit ECA3524 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 50119238 Common - p-hydroxybenzoic acid efflux subunit AaeA ECA0278 147 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 50121852 Common - 3-oxoacyl-(acyl carrier protein) synthase II ECA2928 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50121219 Common - 23S rRNA pseudouridylate synthase B ECA2291 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 50119907 Common speC ornithine decarboxylase, constitutive ECA0967 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 50121292 Pathogen - putative lipoprotein ECA2364 1 None None None 50119206 Common - putative amino-acid transport system permease protein ECA0246 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50122059 Common - PTS system, cellobiose-specific IIa component ECA3136 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 50120865 Common pdxH pyridoxamine 5'-phosphate oxidase ECA1935 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 50121242 Common - predicted hydrolase ECA2314 139 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 50121019 Common - putative signaling membrane protein ECA2091 163 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 50120875 Common - putative lipoprotein ECA1947 12 COG5618 COG5618, Predicted periplasmic lipoprotein General function prediction only 50120199 Common bcp thioredoxin-dependent thiol peroxidase ECA1260 212 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 50119544 Pathogen - hypothetical protein ECA0594 3 None None None 50119346 Common - hypothetical protein ECA0387 35 COG4269 COG4269, Predicted membrane protein Function unknown 50119849 Common - putative DNA-3-methyladenine glycosylase ECA0907 110 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 50121719 Common cyaB adenylate cyclase ECA2795 27 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 50122665 Common - hypothetical protein ECA3743 16 None None None 50123105 Common cyaY frataxin-like protein ECA4185 44 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 50121339 Common osmE DNA-binding transcriptional activator ECA2411 10 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 50123017 Pathogen - hypothetical protein ECA4097 4 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 50120436 Common nlpA lipoprotein-28 precursor ECA1498 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 50122916 Common - putative DNA topoisomerase ECA3996 244 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 50120543 Pathogen - hypothetical plasmid protein ECA1610 1 None None None 50122518 Common msrA methionine sulfoxide reductase A ECA3597 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 50122684 Common - putative alcohol dehydrogenase ECA3762 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 50123270 Common - hypothetical protein ECA4350 15 COG4517 COG4517, Uncharacterized protein conserved in bacteria Function unknown 50123281 Common - putative peptidase ECA4361 35 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 50122670 Common - ABC transporter, ATP-binding protein ECA3748 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 50119108 Common rpmG 50S ribosomal protein L33 ECA0147 136 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 50122890 Common frdB fumarate reductase iron-sulfur subunit ECA3970 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 50121477 Common - pectate lyase ECA2553 18 None None None 50119681 Common - putative aldo/keto reductase ECA0736 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 50123352 Common - PTS system, IIbc component ECA4434 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 50119995 Common - hypothetical protein ECA1055 9 None None None 50122568 Common licC PTS system, lichenan-specific IIc component ECA3647 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 50120486 Common - ABC transporter ATP binding protein ECA1551 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 50121046 Common hecA2 hemolysin/hemagglutinin-like protein HecA precursor ECA2118 86 None None None 50121814 Pathogen - hypothetical protein ECA2890 1 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 50121519 Common - hypothetical protein ECA2595 42 COG1944 COG1944, Uncharacterized conserved protein Function unknown 50121265 Common topB DNA topoisomerase III ECA2337 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 50121295 Common - hypothetical protein ECA2367 35 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 50122091 Common mgtE magnesium transporter ECA3169 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 50121818 Common - putative plasmid-related protein ECA2894 4 None None None 50123127 Common wecC UDP-N-acetyl-D-mannosamine dehydrogenase ECA4207 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 50120980 Common - GntR-family transcriptional regulator ECA2052 196 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50120297 Common sdhD succinate dehydrogenase cytochrome b556 small membrane subunit ECA1358 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 50118982 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A ECA0017 102 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 50121262 Common - hypothetical protein ECA2334 133 COG2860 COG2860, Predicted membrane protein Function unknown 50120031 Common - GntR-family transcriptional regulator ECA1092 144 COG2186 FadR, Transcriptional regulators Transcription 50120085 Common bolA transcriptional regulator BolA ECA1146 98 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 50121863 Common nifL nitrogen fixation regulatory protein ECA2939 117 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 50121052 Pathogen - hypothetical protein ECA2124 1 None None None 50121044 Common hecB putative hemolysin activator protein ECA2116 66 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 50122768 Common - putative xylosidase/arabinosidase ECA3847 45 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 50119842 Common tehB tellurite resistance protein TehB ECA0900 28 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 50122727 Common mutT nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP ECA3805 169 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 50122856 Common mutL DNA mismatch repair protein ECA3936 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 50120119 Common adk adenylate kinase ECA1180 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 50119365 Common - putative integrase (partial) ECA0407 68 None None None 50120029 Common - hypothetical protein ECA1089 63 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 50119559 Common cfl coronafacate ligase ECA0609 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50121957 Common - hypothetical protein ECA3034 35 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 50122557 Pathogen - hypothetical protein ECA3636 3 None None None 50123119 Common - putative transport protein YifK ECA4199 123 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 50122715 Common - putatuve glycosysl hydrolase ECA3793 22 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 50122198 Common recO DNA repair protein RecO ECA3276 90 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 50119067 Common expR quorum-sensing transcriptional regulator ECA0106 51 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 50121671 Common - nucleoid-associated protein NdpA ECA2747 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 50122833 Common pgk phosphoglycerate kinase ECA3912 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 50120518 Common - hypothetical protein ECA1584 38 COG4338 COG4338, Uncharacterized protein conserved in bacteria Function unknown 50119191 Common thiF thiamine biosynthesis protein ThiF ECA0230 205 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 50119424 Common - putative Na+ dependent nucleoside transporter-family protein ECA0473 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 50120319 Common zitB zinc transporter ZitB ECA1380 197 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 50123238 Common ugpQ cytoplasmic glycerophosphodiester phosphodiesterase ECA4318 138 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 50122218 Common cysA sulphate ABC transporter ATP-binding protein ECA3296 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 50121639 Common - putative esterase ECA2715 100 COG0627 COG0627, Predicted esterase General function prediction only 50122752 Common leuA 2-isopropylmalate synthase ECA3831 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 50119467 Common - hypothetical protein ECA0516 140 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 50122630 Pathogen - putative phage-related membrane protein ECA3709 1 None None None 50120759 Common - putative Crp/Fnr-family of transcriptional regulator ECA1829 110 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 50120951 Common - putative siderophore-interacting protein ECA2023 58 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 50120947 Common - hypothetical protein ECA2020 3 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 50119798 Common - ABC transporter permease protein ECA0855 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50122042 Common - hypothetical protein ECA3119 13 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 50122653 Common - putative phage-related protein ECA3731A 8 None None None 50120551 Common virB6 putative conjugal transfer protein ECA1617 22 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 50119168 Common fadB multifunctional fatty acid oxidation complex subunit alpha ECA0208 191 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 50119085 Pathogen - putative lipoprotein ECA0124 1 None None None 50119157 Common - hypothetical protein ECA0197 26 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 50121678 Common - putative prophage primase ECA2754 54 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 50122973 Common - short chain dehydrogenase ECA4053 218 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50120607 Common - integrase (partial) ECA1673 13 None None None 50121723 Common - tRNA-dihydrouridine synthase C ECA2799 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 50120704 Common - hypothetical protein ECA1771 8 None None None 50123079 Common - gluconokinase (partial) ECA4159 61 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 50119074 Common - hypothetical protein ECA0113 27 None None None 50120111 Common - hypothetical protein ECA1172 15 None None None 50120973 Common - putative NAD dependent epimerase/dehydratase ECA2045 218 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50122679 Common - ABC transporter membrane protein ECA3757 184 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 50119062 Common xylR xylose operon regulatory protein ECA0101 108 COG1609 PurR, Transcriptional regulators Transcription 50120534 Common - transposase (partial) ECA1601 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 50120389 Common - putative protease ECA1450 27 COG4934 COG4934, Predicted protease Posttranslational modification, protein turnover, chaperones 50120569 Pathogen - hypothetical protein ECA1637 1 None None None 50121281 Common - hypothetical protein ECA2353 28 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 50120014 Common fecD iron-dicitrate transporter subunit FecD ECA1074 187 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50123335 Common dgoA2 2-dehydro-3-deoxy-6-phosphogalactonate aldolase ECA4417 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 50119573 Common groES co-chaperonin GroES ECA0624 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 50120709 Pathogen - hypothetical protein ECA1776 2 None None None 50122795 Common fkpB FkbP-type 16 kDa peptidyl-prolyl cis-trans isomerase ECA3874 130 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 50122346 Pathogen - hypothetical protein ECA3422 1 None None None 50120649 Common fliP flagellar biosynthesis protein FliP ECA1716 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 50120308 Common - acyl-CoA thioester hydrolase YbgC ECA1369 128 COG0824 FcbC, Predicted thioesterase General function prediction only 50119287 Common - putative glutathionylspermidine synthase ECA0328 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 50119417 Common smp hypothetical protein ECA0466 17 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 50122482 Common - LysR-family transcriptional regulator ECA3561 107 COG0583 LysR, Transcriptional regulator Transcription 50119883 Common - putative fimbrial chaperone ECA0941 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 50122291 Common recA recombinase A ECA3369 223 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 50119495 Common rci shufflon-specific DNA recombinase ECA0546 102 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 50119628 Common rpoD RNA polymerase sigma factor RpoD ECA0680 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 50120301 Common sucB dihydrolipoamide acetyltransferase ECA1362 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 50121763 Common - putative lipid kinase ECA2839 114 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 50122016 Common - hypothetical protein ECA3093 24 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 50123322 Common - hypothetical protein ECA4404 10 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 50119361 Common holC DNA polymerase III subunit chi ECA0403 51 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 50120378 Common rfbK phosphomannomutase ECA1439 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 50121505 Common - hypothetical protein ECA2581 78 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50121010 Pathogen hrpO type III secretion protein ECA2082 1 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 50121544 Common - head completion/stabilization protein L ECA2619 16 None None None 50119933 Common recC exonuclease V subunit gamma ECA0993 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 50122802 Common dnaJ chaperone protein DnaJ ECA3881 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 50122453 Common pcm protein-L-isoaspartate O-methyltransferase ECA3532 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 50119774 Common - putative transposase (partial) ECA0831 6 None None None 50119610 Common - 6-phospho-beta-glucosidase ECA0662 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50119381 Common - hypothetical protein ECA0430 4 None None None 50119892 Common - TetR-family transcriptional regulator ECA0950 39 COG1309 AcrR, Transcriptional regulator Transcription 50120366 Common - putative dTDP-glucose 4,6-dehydratase ECA1427 2 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50122512 Common - hypothetical protein ECA3591 170 COG0344 COG0344, Predicted membrane protein Function unknown 50122054 Pathogen - hypothetical protein ECA3131 1 None None None 50121174 Common - hypothetical protein ECA2246 39 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 50120233 Common cspE cold shock protein E ECA1294 181 COG1278 CspC, Cold shock proteins Transcription 50120835 Common - short chain dehydrogenase ECA1905 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 50121107 Common - hypothetical protein ECA2180 4 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 50120726 Common rpmF 50S ribosomal protein L32 ECA1793 98 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 50121366 Common icd isocitrate dehydrogenase ECA2439 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 50123130 Common wecA undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase ECA4210 132 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 50122926 Common rpoA DNA-directed RNA polymerase subunit alpha ECA4006 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 50122373 Common - hypothetical protein ECA3450 10 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 50120106 Common rpmJ 50S ribosomal protein L36 ECA1167 20 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 50122639 Common - conserved hypothetical phage-related protein ECA3718 18 None None None 50123112 Common - putative peptidase ECA4192 167 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 50119178 Common nusG transcription antitermination protein NusG ECA0218 215 COG0250 NusG, Transcription antiterminator Transcription 50122647 Common - putative phage-related protein ECA3726 14 COG4387 COG4387, Mu-like prophage protein gp36 Function unknown 50120447 Common - hypothetical protein ECA1512 18 COG4393 COG4393, Predicted membrane protein Function unknown 50120773 Common hmuV hemin transport system ATP-binding protein ECA1843 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 50122776 Common djlA Dna-J like membrane chaperone protein ECA3855 46 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 50120265 Common nagB glucosamine-6-phosphate deaminase ECA1326 82 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 50123349 Common - hypothetical protein ECA4431 18 COG3673 COG3673, Uncharacterized conserved protein Function unknown 50122301 Common - putative glycosyltransferase ECA3379 38 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 50120639 Common flgE flagellar hook protein FlgE ECA1705 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 50119975 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase ECA1035 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 50122317 Pathogen - hypothetical protein ECA3393 2 None None None 50122134 Common - hypothetical protein ECA3212 6 None None None 50122381 Common - hypothetical protein ECA3458 9 None None None 50119757 Common - putative iron sensor protein ECA0814 40 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 50121562 Common - phage integrase ECA2637 180 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50119227 Common mreB rod shape-determining protein ECA0267 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 50119397 Common - ABC transporter permease protein ECA0446 213 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50120522 Common - hypothetical protein ECA1588 6 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 50122503 Common - hypothetical protein ECA3582 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 50121074 Common - putative branched-chain amino acid transport system, permease component ECA2146 155 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 50123366 Common - hypothetical protein ECA4448 30 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 50120723 Common rluC 23S rRNA pseudouridylate synthase C ECA1790 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 50119555 Pathogen cfa4 coronafacic acid synthetase component ECA0605 2 None None None 50122204 Common rseB periplasmic negative regulator of sigmaE ECA3282 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 50122602 Common - hypothetical protein ECA3681 18 None None None 50121156 Pathogen - hypothetical protein ECA2229 1 None None None 50119049 Common mtlD mannitol-1-phosphate 5-dehydrogenase ECA0088 86 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 50122911 Common aceB malate synthase ECA3991 69 COG2225 AceB, Malate synthase Energy production and conversion 50121696 Common - hypothetical protein ECA2772 113 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 50119814 Common mtr tryptophan permease ECA0872 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 50121445 Common mviN putative virulence factor ECA2521 195 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 50122435 Common nupC2 nucleoside permease ECA3514 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 50121328 Common kduI1 5-keto-4-deoxyuronate isomerase ECA2400 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 50123120 Common wecG putative UDP-N-acetyl-D-mannosaminuronic acid transferase ECA4200 109 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 50119803 Common tktA1 transketolase ECA0861 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 50119999 Common - putative integrase ECA1059 19 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50119040 Pathogen - hypothetical protein ECA0079 1 None None None 50123194 Common - putative carbon-nitrogen hydrolase ECA4274 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 50122279 Common trmD tRNA (guanine-N(1)-)-methyltransferase ECA3357 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 50119474 Pathogen - hypothetical protein ECA0522A 4 None None None 50121404 Common zwf glucose-6-phosphate 1-dehydrogenase ECA2479 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 50122126 Pathogen - hypothetical protein ECA3204 1 COG4907 COG4907, Predicted membrane protein Function unknown 50119857 Common - hypothetical protein ECA0915 131 COG0657 Aes, Esterase/lipase Lipid metabolism 50121256 Common hns2 global DNA-binding transcriptional dual regulator H-NS ECA2328 28 COG2916 Hns, DNA-binding protein H-NS General function prediction only 50119915 Common - hypothetical protein ECA0975 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 50119023 Common - hypothetical protein ECA0061 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 50119295 Common - LysR-family transcriptional regulator ECA0336 171 COG0583 LysR, Transcriptional regulator Transcription 50119220 Common accC acetyl-CoA carboxylase biotin carboxylase subunit ECA0260 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 50120631 Common flhA flagellar biosynthesis protein A ECA1697 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 50121116 Common hemA glutamyl-tRNA reductase ECA2189 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 50119503 Common - hypothetical protein ECA0554 10 None None None 50119654 Pathogen - hypothetical protein (partial) ECA0707A 1 None None None 50121811 Pathogen - hypothetical protein ECA2887 1 None None None 50121439 Common - hypothetical protein ECA2515 5 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 50120066 Common ribH riboflavin synthase subunit beta ECA1127 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 50121129 Common - hypothetical protein ECA2203 11 None None None 50119737 Common - putative type IV pilus protein ECA0792 222 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 50120050 Common phoR phosphate regulon sensor protein ECA1111 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 50121220 Common - hypothetical protein ECA2292 213 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 50123321 Common ibpA heat shock protein IbpA ECA4403 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 50119316 Common - substrate-binding periplasmic protein ECA0357 105 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 50121025 Pathogen hrpE type III secretion protein ECA2097 2 None None None 50122871 Common - LysE-type translocator ECA3951 118 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50119126 Common rfaD ADP-L-glycero-D-mannoheptose-6-epimerase ECA0165 220 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50123204 Pathogen - hypothetical protein ECA4284 1 None None None 50119252 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase ECA0292 103 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 50120683 Common - hypothetical protein ECA1750 17 COG3120 COG3120, Uncharacterized protein conserved in bacteria Function unknown 50122359 Common - putative chaperone ECA3436 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 50122175 Common pemA pectinesterase A ECA3253 15 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 50120042 Common aroL shikimate kinase II ECA1103 196 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 50119183 Common rpoB DNA-directed RNA polymerase subunit beta ECA0223 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 50121432 Common - putative integrase/recombinase ECA2508 52 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 50122948 Common rplB 50S ribosomal protein L2 ECA4028 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 50122583 Common - putative cytochrome ECA3662 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 50123001 Common cysG siroheme synthase ECA4081 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 50123406 Common - hypothetical protein ECA4490 97 COG2962 RarD, Predicted permeases General function prediction only 50119214 Pathogen - hypothetical protein ECA0254 1 None None None 50123066 Common - hypothetical protein ECA4146 7 None None None 50121456 Common pqiB paraquat-inducible protein B ECA2532 69 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 50122957 Common rpsG 30S ribosomal protein S7 ECA4037 236 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 50119270 Common budC acetoin reductase ECA0310 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50120412 Common - hypothetical protein ECA1474 17 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 50120238 Common - hypothetical protein ECA1299 54 COG2921 COG2921, Uncharacterized conserved protein Function unknown 50123208 Pathogen - hypothetical protein ECA4288 2 None None None 50121178 Common - putative aminotransferase ECA2250 230 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 50122789 Common - hypothetical protein ECA3868 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 50119542 Pathogen - hypothetical protein ECA0592 1 None None None 50121931 Common - hypothetical protein ECA3008 18 COG3721 HugX, Putative heme iron utilization protein Inorganic ion transport and metabolism 50122536 Common - putative methyl-accepting chemotaxis protein ECA3615 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50119622 Common - putative phage-related protein ECA0674 12 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 50121318 Common rrmA 23S rRNA methyltransferase A ECA2390 56 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50119101 Common rph ribonuclease PH ECA0140 209 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 50119344 Common - hypothetical protein ECA0385 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 50119746 Common - hypothetical protein ECA0801 130 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50122950 Common rplD 50S ribosomal protein L4 ECA4030 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 50123054 Common - predicted gluconate transport-associated protein ECA4134 52 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 50121352 Pathogen - hypothetical protein ECA2424 1 None None None 50122207 Common nadB L-aspartate oxidase ECA3285 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 50120987 Common - putative phosphotransferase ECA2059 20 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 50121973 Common hisJ histidine-binding periplasmic protein ECA3050 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50119294 Common parE DNA topoisomerase IV subunit B ECA0335 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 50120034 Common pehA endo-polygalacturonase ECA1095 25 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 50119700 Common rafR LysR-family raffinose operon repressor ECA0755 126 COG1609 PurR, Transcriptional regulators Transcription 50121787 Common - hypothetical protein ECA2863 11 COG3311 AlpA, Predicted transcriptional regulator Transcription 50120195 Common uraA uracil transporter ECA1256 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 50121039 Pathogen - potential HrpW-specific chaperone ECA2111 1 None None None 50121654 Common sotA sugar efflux transporter ECA2730 59 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122556 Common - hypothetical protein ECA3635 49 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119409 Common visB 2-octaprenyl-6-methoxyphenyl hydroxylase ECA0458 125 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 50122308 Common - hypothetical protein ECA3384 16 None None None 50123328 Common ssuA alkanesulfonate transporter substrate-binding subunit ECA4410 104 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 161501875 Common - putative oxidoreductase ECA2269 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50119058 Common xylA xylose isomerase ECA0097 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 50120896 Common - putative glycosyl hydrolase ECA1968 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 50121097 Common - hypothetical protein ECA2169 3 None None None 50121541 Common - hypothetical protein ECA2616 32 COG3926 zliS, Putative secretion activating protein General function prediction only 50119487 Pathogen - hypothetical protein ECA0539 1 None None None 50121463 Common pepN aminopeptidase N ECA2539 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 50120939 Common rstB sensor protein RstB ECA2012 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50122505 Common rfaE bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase ECA3584 171 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 50121023 Common hrcJ type III secretion protein ECA2095 54 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 50119323 Common scrK aminoimidazole riboside kinase ECA0364 192 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 50121394 Common - hypothetical protein ECA2468 11 None None None 50121604 Common nfsA nitroreductase A ECA2680 61 COG0778 NfnB, Nitroreductase Energy production and conversion 50122998 Pathogen - hypothetical protein ECA4078 1 None None None 50119532 Pathogen - putative plasmid-related protein ECA0583 2 None None None 50119742 Common - hypothetical protein ECA0797 2 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 50121139 Common - hypothetical protein ECA2213 63 COG3496 COG3496, Uncharacterized conserved protein Function unknown 50121308 Common sdaA L-serine dehydratase 1 ECA2380 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 50122625 Common - conserved hypothetical phage-related protein ECA3704 17 None None None 50119791 Common - putative sugar ABC transporter, periplasmic binding protein ECA0848 29 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50120305 Common cydB1 cytochrome D ubiquinol oxidase subunit II ECA1366 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 50119602 Common - putative oxidoreductase ECA0653 145 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50121162 Common - putative transcriptional regulator ECA2235 92 COG1733 COG1733, Predicted transcriptional regulators Transcription 50121402 Common purT phosphoribosylglycinamide formyltransferase 2 ECA2477 194 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 50121753 Common - predicted inner membrane protein ECA2829 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 50119374 Common - hypothetical protein ECA0423 102 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 50119698 Common lacY galactoside permease ECA0753 39 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 50122202 Common lepA GTP-binding protein LepA ECA3280 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 50122847 Common fbp fructose-1,6-bisphosphatase ECA3927 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 50119981 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase ECA1041 181 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 50120769 Common gntV gluconokinase ECA1839 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 50120214 Common - TonB-dependent ferrichrome-iron receptor ECA1275 95 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 50121885 Common - ABC transporter permease protein ECA2961 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122963 Common pmrC predicted metal dependent hydrolase ECA4043 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 50121850 Pathogen - putative glutathione-S-transferase (partial) ECA2926 1 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50122365 Common - hypothetical protein ECA3442 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 50121674 Common intA prophage integrase ECA2750 106 COG0582 XerC, Integrase DNA replication, recombination, and repair 50122992 Common - ABC transporter ATP-binding protein ECA4072 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121130 Common pntA NAD(P) transhydrogenase subunit alpha ECA2204 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 50121734 Common acr TonB-dependent ferric achromobactin receptor ECA2810 71 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50119723 Pathogen - hypothetical protein ECA0778 2 None None None 50120801 Common arbB 6-phospho-beta-glucosidase ECA1871 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50122030 Common outF general secretion pathway protein F ECA3107 141 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 50121090 Common - hypothetical protein ECA2162 24 COG4283 COG4283, Uncharacterized conserved protein Function unknown 50122633 Common - putative phage-related membrane protein ECA3712 4 None None None 50120930 Common - hypothetical protein ECA2003 19 None None None 50121928 Common - glutamine amidotransferase ECA3005 197 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 50119027 Common - hypothetical protein ECA0065 61 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 50119009 Common - hypothetical protein ECA0047 135 COG2081 COG2081, Predicted flavoproteins General function prediction only 50123097 Common corA magnesium/nickel/cobalt transporter CorA ECA4177 142 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 50122905 Common foxA ferrioxamine B receptor ECA3985 116 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 50119860 Common rspB putative starvation sensing zinc-binding dehydrogenase ECA0918 212 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 50119123 Common waaL1 O-antigen ligase ECA0162 7 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 50120449 Common - putative permease ECA1514 80 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 50120620 Common flhC transcriptional activator FlhC ECA1686 27 None None None 50121796 Common - putative flagellin ECA2872 110 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 50120099 Common glnK nitrogen regulatory protein P-II ECA1160 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 50122886 Common psd phosphatidylserine decarboxylase ECA3966 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 50120179 Common hyfH hydrogenase 4 subunit H ECA1240 189 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 50120758 Pathogen - hypothetical protein ECA1828 1 None None None 50119609 Common - PTS system, beta-glucoside-specific IIabc component ECA0661 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50121276 Common - hypothetical protein ECA2348 70 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 50119201 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ECA0241 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 50121103 Common - hypothetical protein ECA2175 17 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 50120944 Common - putative RNA polymerase sigma factor ECA2017 136 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50120073 Common thiI thiamine biosynthesis protein ThiI ECA1134 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 50119869 Common - TonB-dependent receptor ECA0927 86 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50119031 Common padC phenolic acid decarboxylase ECA0069 11 COG3479 COG3479, Phenolic acid decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 50120090 Common hupB transcriptional regulator HU subunit beta ECA1151 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 50121111 Common pth peptidyl-tRNA hydrolase ECA2184 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 50120691 Common - hypothetical protein ECA1758 10 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 161501869 Common bcsC cellulose synthase subunit BcsC ECA4374 19 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 50120193 Common purM phosphoribosylaminoimidazole synthetase ECA1254 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 50122681 Common - DeoR-family transcriptional regulator ECA3759 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 50120712 Common htrB lipid A biosynthesis lauroyl acyltransferase ECA1779 89 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 50120900 Common fabI enoyl-(acyl carrier protein) reductase ECA1972 232 COG0623 FabI, Enoyl- acyl-carrier-protein 50121573 Common - thioredoxin reductase ECA2649 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 50122862 Common ahpC alkyl hydroperoxide reductase subunit C ECA3942 217 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 50122822 Common - putative ABC transporter ATP-binding protein ECA3901 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 50122827 Common rpiA ribose-5-phosphate isomerase A ECA3906 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 50119279 Common - hypothetical protein ECA0319 68 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 50120668 Common - hypothetical protein ECA1735 16 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 50119116 Pathogen - hypothetical protein ECA0155 1 None None None 50120254 Common lnt apolipoprotein N-acyltransferase ECA1315 166 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 50122106 Common - multidrug efflux system subunit MdtA ECA3184 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50123197 Common - hypothetical protein ECA4277 8 COG5435 COG5435, Uncharacterized conserved protein Function unknown 50123393 Common pstS phosphate transporter subunit ECA4477 132 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 50121991 Common mepA penicillin-insensitive murein endopeptidase ECA3068 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 50122793 Common - dihydrodipicolinate reductase ECA3872 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 50119300 Common - PTS system, IIb component ECA0341 64 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 50121165 Pathogen flxA hypothetical protein ECA2237 1 None None None 50122319 Common - hypothetical protein ECA3395 2 None None None 50121805 Common uvrC excinuclease ABC subunit C ECA2881 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 50120143 Common - phosphotransfer intermediate protein in two-component regulatory system with RcsBC ECA1204 115 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50120001 Common - putative integrase ECA1061 15 COG4688 COG4688, Uncharacterized protein conserved in bacteria Function unknown 50120272 Common - LexA regulated protein ECA1333 21 None None None 50121703 Common - putative transglycosylase ECA2779 47 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 50120183 Common hyfD hydrogenase 4 subunit D ECA1244 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 50121288 Common fadR fatty acid metabolism regulator ECA2360 67 COG2186 FadR, Transcriptional regulators Transcription 50120282 Pathogen - hypothetical protein ECA1343 1 None None None 50120082 Common cyoA cytochrome o ubiquinol oxidase subunit II ECA1143 106 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 50119562 Common - hypothetical protein ECA0612 12 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 50120135 Common - hypothetical protein ECA1196 220 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 50121196 Common - putative sodium bile acid symporter ECA2268 61 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 50122233 Common fhuD iron-hydroxamate transporter substrate-binding subunit ECA3311 39 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50119160 Common tatB sec-independent protein translocase ECA0200 35 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 50122025 Common outK general secretion pathway protein K ECA3102 42 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 50123351 Common - pts system, cellobiose-specific IIa component ECA4433 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 50122473 Common - putative polygalacturonase ECA3552 21 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 50122295 Common marC multiple drug resistance protein MarC ECA3373 159 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 50122811 Common thrB homoserine kinase ECA3890 134 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 50119903 Pathogen ccdA2 toxin addiction system:antidote ECA0963 5 COG5302 COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid General function prediction only 50121245 Common - methyl-accepting chemotaxis protein ECA2317 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50122037 Pathogen outS general secretion pathway lipoprotein ECA3114 4 None None None 50122281 Common rpsP 30S ribosomal protein S16 ECA3359 209 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 50122867 Common - putative D-isomer specific 2-hydroxyacid dehydrogenase ECA3947 226 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 50123408 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase ECA4492 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50120166 Common hybB predicted hydrogenase 2 cytochrome b type component ECA1227 24 COG5557 COG5557, Polysulphide reductase Energy production and conversion 50119181 Common rplJ 50S ribosomal protein L10 ECA0221 188 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 50121414 Common - PTS system, cellobiose-specific IIa component ECA2489 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 50119458 Common - putative capsular polysaccharide bisynthesis glycosyl transferase ECA0507 167 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 50121868 Common nifV homocitrate synthase ECA2944 209 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 50120313 Common pal peptidoglycan-associated outer membrane lipoprotein ECA1374 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 50122407 Common masA enolase-phosphatase ECA3486 31 COG4229 COG4229, Predicted enolase-phosphatase Energy production and conversion 50121486 Common - putative iron ABC transporter permease component ECA2562 93 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 50121912 Pathogen - conserved hypothetical protein (partial) ECA2988 1 COG5464 COG5464, Uncharacterized conserved protein Function unknown 50119924 Common mutH DNA mismatch repair protein ECA0984 28 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 50121324 Common - putative fructosamine kinase ECA2396 70 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 50122245 Common panD aspartate alpha-decarboxylase ECA3323 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 50120580 Pathogen - hypothetical protein ECA1648 1 None None None 50121482 Common - hypothetical protein ECA2558 148 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 50120587 Pathogen - putative lipoprotein ECA1655 2 None None None 50120912 Common pspC DNA-binding transcriptional activator ECA1985 31 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 50119261 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase ECA0301 219 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 50119167 Common fadA 3-ketoacyl-CoA thiolase ECA0207 179 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 50119528 Pathogen - hypothetical protein ECA0579 4 None None None 50119451 Common - putative capsular polysaccharide biosynthesis protein ECA0500 7 None None None 50122222 Common cdaR carbohydrate diacid transcriptional activator CdaR ECA3300 47 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 50121386 Common proQ putative solute/DNA competence effector ECA2460 34 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 50121985 Common flk predicted flagella assembly protein ECA3062 10 None None None 50120466 Common - D-cysteine desulfhydrase ECA1531 68 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 50120919 Common mppA periplasmic murein peptide-binding protein ECA1992 201 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 50122497 Common gudX probable glucarate dehydratase ECA3576 48 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50121955 Common hexA2 LysR-family transcriptional regulator of motility and virulence ECA3032 180 COG0583 LysR, Transcriptional regulator Transcription 50121290 Common dsbB disulfide bond formation protein B ECA2362 35 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 50123314 Pathogen - hypothetical protein ECA4396 1 None None None 50119297 Common - hypothetical protein ECA0338 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 50122695 Common sgcA putative phosphotransferase enzyme II, A component ECA3773 53 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 50120828 Common napF ferredoxin-type protein ECA1898 65 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 50121203 Common araA L-arabinose isomerase ECA2275 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 50120325 Common - hypothetical protein ECA1386 26 COG5569 COG5569, Uncharacterized conserved protein Function unknown 50120340 Common glk glucokinase ECA1401 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 50120790 Common sufB cysteine desulfurase activator complex subunit SufB ECA1860 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 50123136 Common ppiC peptidyl-prolyl cis-trans isomerase C ECA4216 143 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 50119679 Common holD DNA polymerase III subunit psi ECA0734 19 COG3050 HolD, DNA polymerase III, psi subunit DNA replication, recombination, and repair 50122661 Common - putative bacteriophage baseplate assembly protein ECA3739 36 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 50122688 Common - hypothetical protein ECA3766 17 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 50123376 Common - putative lipoprotein ECA4459 21 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 50123192 Common tpiA triosephosphate isomerase ECA4272 223 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 50123088 Common - predicted hydrolase ECA4168 117 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 50123005 Common occJ octopine-binding periplasmic protein ECA4085 153 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50119310 Common - probable nitroreductase ECA0351 114 COG0778 NfnB, Nitroreductase Energy production and conversion 50122655 Common - putative phage-related protein ECA3733 8 COG3499 COG3499, Phage protein U General function prediction only 50122952 Common rpsJ 30S ribosomal protein S10 ECA4032 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 50122545 Common - methyl-accepting chemotaxis protein ECA3624 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121065 Common - hypothetical protein ECA2137 11 None None None 50119332 Common - hypothetical protein ECA0373 46 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50120821 Pathogen - hypothetical protein ECA1891 1 None None None 50121617 Common - hypothetical protein ECA2693 19 COG3787 COG3787, Uncharacterized protein conserved in bacteria Function unknown 50122255 Common speE spermidine synthase ECA3333 129 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 50121795 Pathogen - hypothetical protein ECA2871 2 None None None 50121479 Common - hypothetical protein ECA2555 97 COG2835 COG2835, Uncharacterized conserved protein Function unknown 50123154 Common - putative ABC transporter permease protein ECA4234 109 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 50119456 Common - probable capsular polysaccharide bisynthesis glycosyl transferase ECA0505 6 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 50119246 Common ptsN sugar-specific enzyme IIA component of PTS ECA0286 131 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 50123300 Common - putative zinc-binding dehydrogenase ECA4382 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 50119838 Common zipA cell division protein ZipA ECA0896 42 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 50122666 Common - GntR-family transcriptional regulator ECA3744 189 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50120147 Common - probable short chain dehydrogenase ECA1208 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50120967 Common - putative ornithine cyclodeaminase ECA2039 88 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 50121235 Pathogen - putative phage-related protein ECA2307 1 None None None 50122945 Common rpsC 30S ribosomal protein S3 ECA4025 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 50120332 Common modA molybdate transporter periplasmic protein ECA1393 142 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 50122111 Common baeR DNA-binding response regulator in two-component regulatory system with BaeS ECA3189 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50119045 Common glyQ glycyl-tRNA synthetase subunit alpha ECA0084 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 50123276 Common - hypothetical protein ECA4356 19 COG3673 COG3673, Uncharacterized conserved protein Function unknown 50118978 Common rbsB D-ribose transporter subunit RbsB ECA0013 129 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50121873 Common nifE nitrogenase iron-molybdenum cofactor biosynthesis protein ECA2949 53 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 50119258 Common - hypothetical protein ECA0298 79 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 50121782 Pathogen - hypothetical protein ECA2858 1 None None None 50119268 Common sspA stringent starvation protein A ECA0308 107 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50123268 Common - hypothetical protein ECA4348 11 COG3776 COG3776, Predicted membrane protein Function unknown 50121596 Common rumB 23S rRNA metyluridine methyltransferase ECA2672 188 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 50123043 Common rexZ regulator of exoenzyme ECA4123 110 COG1414 IclR, Transcriptional regulator Transcription 50121495 Common citF citrate lyase alpha chain ECA2571 28 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 50120392 Common adrA putative signaling membrane protein ECA1453 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50119603 Common - hypothetical protein ECA0654 91 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 50120349 Common - putative ATPase ECA1410 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 50121279 Common dadA D-amino acid dehydrogenase small subunit ECA2351 135 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 50121970 Common hisP histidine/lysine/arginine/ornithine transporter subunit ECA3047 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 50120211 Common - TonB-like protein ECA1272 45 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 50122412 Common pucG purine catabolism protein ECA3491 155 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 50119449 Common phnP carbon-phosphorus lyase complex accessory protein ECA0498 68 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 50123356 Common gyrB DNA gyrase subunit B ECA4438 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 50121216 Common sohB predicted inner membrane peptidase ECA2288 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 50120351 Common dcd deoxycytidine triphosphate deaminase ECA1412 161 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 50119887 Pathogen - hypothetical protein ECA0945 1 None None None 50122410 Common - hypothetical protein ECA3489 189 COG0388 COG0388, Predicted amidohydrolase General function prediction only 50119594 Common uxaC glucuronate isomerase ECA0645 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 50122538 Common prfH peptide chain release factor-like protein ECA3617 214 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 50119145 Common udp uridine phosphorylase ECA0185 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 50123264 Common ftsX cell division protein FtsX ECA4344 128 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 50122060 Common sfuA iron(III)-binding periplasmic protein ECA3137 122 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 50122159 Common iscS cysteine desulfurase ECA3237 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 50120262 Common asnB asparagine synthetase B ECA1323 159 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 50121622 Common ehpE putative phenazine antibiotic biosynthesis protein ECA2698 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 50120121 Common - putative cation:proton antiport protein ECA1182 212 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 50122906 Common - AraC-family transcriptional regulator ECA3986 97 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50121823 Pathogen - hypothetical protein ECA2899 2 None None None 50120381 Common rfbA glucose-1-phosphate thymidylyltransferase ECA1442 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 50121141 Common - putative short-chain dehydrogenase ECA2215 231 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 50119667 Common - putative protease ECA0722 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 50122074 Common cysS cysteinyl-tRNA synthetase ECA3151 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50118992 Common glnA glutamine synthetase ECA0029 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 50120817 Common ccmF cytochrome C-type biogenesis protein ECA1887 151 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 50121641 Common - hypothetical protein ECA2717 5 None None None 50120505 Common tdcB putative threonine dehydratase catabolic ECA1571 193 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 50119650 Common secG preprotein translocase subunit SecG ECA0702 128 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 50122329 Pathogen - hypothetical protein ECA3405 1 None None None 50120291 Common - putative allophanate hydrolase subunit 2 ECA1352 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 50119631 Common gcp O-sialoglycoprotein endopeptidase ECA0683 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 50119586 Common - hypothetical protein ECA0637 9 None None None 50121699 Common - hypothetical protein ECA2775 7 None None None 50123216 Common atsC sulfate ester ABC transporter ATP-binding protein ECA4296 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50119854 Common - hypothetical protein ECA0912 186 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120247 Common rlpB LPS-assembly lipoprotein RplB ECA1308 46 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 50122447 Common metQ DL-methionine transporter substrate-binding subunit ECA3526 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 50123309 Common dppD dipeptide transporter ATP-binding subunit ECA4391 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121837 Common - putative DNA-binding protein ECA2913 4 COG2916 Hns, DNA-binding protein H-NS General function prediction only 50120909 Common pspF phage shock protein operon transcriptional activator ECA1982 170 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 50121580 Common clpA ATP-dependent Clp protease ATP-binding subunit ECA2656 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 50123185 Common - hypothetical protein ECA4265 21 COG3074 COG3074, Uncharacterized protein conserved in bacteria Function unknown 50121529 Common - putative bacteriophage tail fiber protein T (tape measure) ECA2605 44 COG5283 COG5283, Phage-related tail protein Function unknown 50122749 Common ilvH acetolactate synthase 3 regulatory subunit ECA3828 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 50121897 Common - LysR-family transcriptional regulator ECA2973 164 COG0583 LysR, Transcriptional regulator Transcription 50122078 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit ECA3156 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 50121895 Common - putative branched-chain amino acid aminotransferase ECA2971 176 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 50123389 Common phoU transcriptional regulator PhoU ECA4473 194 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 50120738 Common ptsG glucose-specific PTS system IIBC components ECA1805 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50121948 Common nuoE NADH dehydrogenase subunit E ECA3025 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 50122114 Common - hypothetical protein ECA3192 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50123147 Common ilvE branched-chain amino acid aminotransferase ECA4227 220 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 50122167 Common - methyl-accepting chemotaxis protein ECA3245 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50122809 Common - hypothetical protein ECA3888 86 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 50121533 Common - putative phage tail protein I ECA2609 28 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 50119643 Common greA transcription elongation factor GreA ECA0695 204 COG0782 GreA, Transcription elongation factor Transcription 50120797 Common pykF pyruvate kinase ECA1867 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 50120881 Common - putative xylose isomerase ECA1953 49 COG4952 COG4952, Predicted sugar isomerase Cell envelope biogenesis, outer membrane 50120762 Common btuC vtamin B12-transporter permease ECA1832 143 COG4139 BtuC, ABC-type cobalamin transport system, permease component Coenzyme metabolism 50121840 Pathogen - hypothetical protein ECA2916 2 None None None 50123272 Common zntA zinc/cadmium/mercury/lead-transporting ATPase ECA4352 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 50120444 Common - methyl-accepting chemotaxis protein ECA1509 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50123037 Common - putative citrate lyase beta chain ECA4117 109 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 50118969 Common yieM hypothetical protein ECA0004 26 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 50120491 Common astC putative sulfate ester transporter, ATP-binding component ECA1556 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50119616 Pathogen - hypothetical protein ECA0668 3 None None None 50119089 Pathogen - hypothetical protein ECA0128 2 None None None 50119352 Common kptA RNA 2'-phosphotransferase ECA0395 45 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 50121229 Common trpA tryptophan synthase subunit alpha ECA2301 210 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 50120995 Common bor lipoprotein ECA2067 7 None None None 50123060 Common - putative glyoxalase ECA4140 12 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 50123090 Common rhtB homoserine/homoserine lactone efflux protein ECA4170 101 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50121587 Common hcr HCP oxidoreductase, NADH-dependent ECA2663 132 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 50122227 Pathogen - putative lipoprotein ECA3305 2 None None None 50121750 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase ECA2826 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 50120925 Common - hypothetical protein ECA1998 9 None None None 50123380 Common - hypothetical protein ECA4463 10 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 50123210 Common - putative phage regulatory protein ECA4290 4 COG1396 HipB, Predicted transcriptional regulators Transcription 50120172 Common hypC hydrogenase isoenzymes formation protein ECA1233 69 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 50123258 Common livG leucine/isoleucine/valine transporter ATP-binding subunit ECA4338 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 50120564 Pathogen - hypothetical protein ECA1632 2 None None None 50120545 Common kikA putative plasmid conjugation protein ECA1612 6 None None None 50120653 Common fliL flagellar basal body-associated protein FliL ECA1720 21 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 50122514 Common ppa inorganic pyrophosphatase ECA3593 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 50120299 Common sdhB succinate dehydrogenase iron-sulfur subunit ECA1360 197 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 50120791 Common sufC cysteine desulfurase ATPase component ECA1861 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 50122626 Common - conserved hypothetical phage-related protein ECA3705 8 None None None 50123345 Common - LysR-family transcriptional regulator ECA4427 181 COG0583 LysR, Transcriptional regulator Transcription 50122798 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase ECA3877 211 COG0196 RibF, FAD synthase Coenzyme metabolism 50120629 Common cheZ chemotaxis regulator CheZ ECA1695 43 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50123390 Common pstB phosphate transporter subunit ECA4474 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 50121648 Common rscR putative DNA-binding transcriptional regulator ECA2724 185 COG0583 LysR, Transcriptional regulator Transcription 50119571 Common aspA aspartate ammonia-lyase ECA0621 215 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 50119796 Common - LacI-family transcriptional regulator ECA0853 125 COG1609 PurR, Transcriptional regulators Transcription 50119363 Common - putative permease ECA0405 123 COG0795 COG0795, Predicted permeases General function prediction only 50120408 Common - ABC transporter, permease protein ECA1469 156 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 50123122 Common wecF 4-alpha-L-fucosyltransferase ECA4202 18 None None None 50120609 Common - putative integrase (partial) ECA1675 5 None None None 50121673 Common - putative sulphatase ECA2749 31 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 50119832 Common - two-component system sensor kinase ECA0890 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50121490 Common - putative amino acid permease ECA2566 180 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 50120815 Common ccmD heme exporter protein D ECA1885 10 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 50121440 Common - hypothetical protein ECA2516 2 None None None 50122428 Common - hypothetical protein ECA3507 61 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 50122717 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase ECA3795 108 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 50121551 Pathogen - putative phage-related protein ECA2626 1 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 50122521 Common - hypothetical protein ECA3600 18 COG3054 COG3054, Predicted transcriptional regulator General function prediction only 50120280 Common kdpB potassium-transporting ATPase subunit B ECA1341 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 50122350 Common - putative phospholipase ECA3426 32 COG4104 COG4104, Uncharacterized conserved protein Function unknown 50119465 Pathogen - hypothetical protein ECA0514 1 None None None 50119978 Common ecfE zinc metallopeptidase ECA1038 213 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 50120554 Common virB4 putative conjugal transfer protein ECA1620 60 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 50122044 Common hsdM subunit M of type I restriction-modification system ECA3121 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 50122979 Common - hypothetical protein ECA4059 105 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50122682 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase 2 ECA3760 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 50119937 Common - putative lacI-family transcriptional regulator ECA0997 127 COG1609 PurR, Transcriptional regulators Transcription 50122195 Common - putative ferredoxin ECA3273 101 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 50123426 Common pelX exopolygalacturonate lyase ECA4510 15 None None None 50119874 Common - permease ECA0932 90 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 50123129 Common wzzE lipopolysaccharide biosynthesis protein WzzE ECA4209 16 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 50120027 Common - putative lipoprotein ECA1087 14 None None None 50122616 Common - phage regulatory protein protein ECA3695 13 COG5566 COG5566, Uncharacterized conserved protein Function unknown 50122590 Common - hypothetical protein ECA3669 74 COG1284 COG1284, Uncharacterized conserved protein Function unknown 50122743 Common ftsI peptidoglycan synthetase ECA3821 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 50122733 Common ftsA cell division protein FtsA ECA3811 178 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 50119866 Common - hypothetical protein ECA0924 38 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 50119638 Common rplU 50S ribosomal protein L21 ECA0690 214 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 50119285 Common - putative plasmid stability protein ECA0326 30 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 50122831 Common - putative mechanosensitive ion channel ECA3910 194 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 50120012 Common - glutathione S-transferase ECA1072 83 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50119436 Common - hypothetical protein ECA0485 6 None None None 50119076 Common - putative fatty acid desaturase ECA0115 15 COG3239 DesA, Fatty acid desaturase Lipid metabolism 50119064 Pathogen - hypothetical protein ECA0103 1 None None None 50121379 Common potD spermidine/putrescine ABC transporter periplasmic substrate-binding protein ECA2453 138 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 50122544 Common - transcriptional repressor NsrR ECA3623 161 COG1959 COG1959, Predicted transcriptional regulator Transcription 50119415 Common radA DNA repair protein RadA ECA0464 207 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 50123149 Common ilvG acetolactate synthase 2 catalytic subunit ECA4229 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 50119931 Common - hypothetical protein ECA0991 10 None None None 50122750 Common ilvI acetolactate synthase 3 catalytic subunit ECA3829 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 50120706 Pathogen - hypothetical protein ECA1773 3 None None None 50123077 Common - putative eubacterial dITP- and XTP- hydrolyzing enzyme ECA4157 159 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 50122897 Common - hypothetical protein ECA3977 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 50123030 Common - putative periplasmic substrate-binding protein ECA4110 41 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50122800 Common nhaR transcriptional activator NhaR ECA3879 125 COG0583 LysR, Transcriptional regulator Transcription 50120989 Common - methyl-accepting chemotaxis protein ECA2061 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121081 Common - ABC transporter, ATP-binding protein ECA2153 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50119662 Common rpsO 30S ribosomal protein S15 ECA0715 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 50122460 Common - amino acid ABC transporter, ATP-binding protein ECA3539 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50123113 Common - putative amino-acid ABC transporter ATP-binding protein ECA4193 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50119078 Common - hypothetical protein ECA0117 11 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 50120235 Common tatE twin argininte translocase protein A ECA1296 63 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 50121122 Common - transposase for insertion sequence element IS4 (partial) ECA2195 17 None None None 50120728 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III ECA1795 232 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 50123021 Pathogen - hypothetical protein ECA4101 1 None None None 50122178 Common - hypothetical protein ECA3256 10 None None None 50122451 Common rpoS RNA polymerase sigma factor RpoS ECA3530 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 50122484 Common - hypothetical protein ECA3563 101 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 50121420 Common ntpA dATP pyrophosphohydrolase ECA2495 39 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 50121503 Common - putative methyl-accepting chemotaxis citrate transducer ECA2579 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120877 Common - putative sugar ABC transporter, permease protein ECA1949 139 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 50123015 Pathogen - hypothetical protein ECA4095 2 None None None 50121186 Common - Rok-family transcriptional regulator ECA2258 155 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 50122700 Common acnB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase ECA3778 209 COG1049 AcnB, Aconitase B Energy production and conversion 50120870 Pathogen - hypothetical protein ECA1940 1 None None None 50122469 Common - hypothetical protein ECA3548 43 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 50123416 Common - hypothetical protein ECA4500 21 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 50121042 Pathogen dspF putative avirulence protein ECA2114 2 None None None 50121512 Common hisF imidazole glycerol phosphate synthase subunit HisF ECA2588 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 50120358 Common wzc tyrosine kinase ECA1419 172 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 50121054 Common - hypothetical protein ECA2126 2 None None None 50121777 Common - hypothetical protein ECA2853 8 None None None 50119956 Common - hypothetical protein ECA1016 72 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 50120741 Common - putative lipoprotein ECA1810 10 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 50119546 Pathogen - hypothetical protein ECA0596 3 None None None 50123103 Common dapF diaminopimelate epimerase ECA4183 202 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 50122032 Common outD general secretion pathway protein D ECA3109 141 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 50120157 Common tyrP tyrosine-specific transport protein ECA1218 34 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 50122326 Pathogen - hypothetical protein ECA3402 3 None None None 50119198 Common hupA transcriptional regulator HU subunit alpha ECA0238 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 50119905 Common - putative regulatory protein ECA0965 24 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 50121668 Common - putative helicase ECA2744 126 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 50119768 Pathogen - hypothetical protein ECA0825 1 None None None 50120201 Common dapA dihydrodipicolinate synthase ECA1262 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 50120536 Common arsC arsenate reductase ECA1603 104 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 50120048 Common sbcD exonuclease subunit SbcD ECA1109 97 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 50119348 Common - hypothetical protein ECA0389 124 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 50119439 Common fom2 phosphonopyruvate decarboxylase ECA0488 37 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 50120493 Common atsR putative sulfate ester transporter, periplasmic binding component ECA1558 89 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 50123409 Common - putative beta-hydroxydecanoyl-ACP dehydrase ECA4493 24 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 50121586 Common hcp hydroxylamine reductase ECA2662 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 50121705 Common prtF protease secretion protein ECA2781 121 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50120197 Common - putative arsenate reductase ECA1258 118 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 50119997 Common - phage-related hypothetical protein ECA1057 15 None None None 50122303 Common pvcA pyoverdine biosynthesis protein ECA3381 11 COG3207 DIT1, Pyoverdine/dityrosine biosynthesis protein Secondary metabolites biosynthesis, transport, and catabolism 50122759 Common - methyl-accepting chemotaxis protein ECA3838 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50119223 Common - putative sulfite oxidase subunit YedZ ECA0263 73 COG2717 COG2717, Predicted membrane protein Function unknown 50120438 Common - probable aspartate racemase ECA1500 91 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 50120626 Common cheR chemotaxis regulator, protein-glutamate methyltransferase ECA1692 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 50123140 Common - hypothetical protein ECA4220 52 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 50121497 Common citD citrate lyase subunit gamma ECA2573 25 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 50121967 Common - putative glutathione-S transferase ECA3044 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50121560 Common - phage regulatory protein ECA2635 4 None None None 50121517 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase ECA2593 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 50121063 Common - periplasmic pectate lyase ECA2135 5 None None None 50123045 Common kduI2 5-keto-4-deoxyuronate isomerase ECA4125 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 50120972 Common - hypothetical protein ECA2044 14 COG2261 COG2261, Predicted membrane protein Function unknown 50120117 Common recR recombination protein RecR ECA1178 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 50121960 Common - hypothetical protein ECA3037 18 COG3013 COG3013, Uncharacterized conserved protein Function unknown 50121048 Pathogen - hypothetical protein ECA2120 2 None None None 50122264 Common gloB probable hydroxyacylglutathione hydrolase ECA3342 203 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 50121332 Common togN binding-protein-dependent transport system, inner membrane component ECA2404 171 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 50121267 Common sppA protease 4 ECA2339 191 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 50121816 Common - hypothetical protein ECA2892 20 None None None 50122566 Common - PTS system, lichenan-specific IIb component ECA3645 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 50119973 Common pyrH uridylate kinase ECA1033 231 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 50120431 Common afuB ferric ABC transporter permease protein ECA1493 223 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 50122604 Common - hypothetical protein ECA3683 21 None None None 50119208 Common - putative transcriptional regulator ECA0248 136 COG1733 COG1733, Predicted transcriptional regulators Transcription 50120982 Common gabD succinate-semialdehyde dehydrogenase [NADP+] ECA2054 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50119721 Common - hypothetical protein ECA0776 14 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50119744 Common - putative outer membrane protein ECA0799 90 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 50120033 Common pelI pectate lyase ECA1094 10 None None None 50120107 Common rpmE2 50S ribosomal protein L31 type B ECA1168 93 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 50122507 Common - hypothetical protein ECA3586 54 COG3025 COG3025, Uncharacterized conserved protein Function unknown 50119990 Common rof Rho-binding antiterminator ECA1050 13 COG4568 Rof, Transcriptional antiterminator Transcription 50123202 Common - DnaG primase-like protein ECA4282 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50121454 Common - methyl-accepting chemotaxis protein ECA2530 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121222 Common - putative glycosyl transferase ECA2294 147 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 50123068 Common glgA glycogen synthase ECA4148 137 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 50119912 Common - hypothetical protein ECA0972 48 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 50120598 Pathogen - hypothetical protein ECA1666 1 None None None 50119823 Common - hypothetical protein ECA0881 10 None None None 50120045 Common rdgC recombination associated protein ECA1106 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 50119839 Common asoB inner membrane protein YjeH ECA0897 68 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 50122554 Common - hypothetical protein ECA3633 24 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 50121812 Common nac nitrogen assimilation regulatory protein (partial) ECA2888 180 COG0583 LysR, Transcriptional regulator Transcription 50122471 Pathogen - hypothetical protein ECA3550 1 None None None 50120476 Pathogen - hypothetical protein ECA1541 1 None None None 50121785 Pathogen - hypothetical protein ECA2861 1 None None None 50119056 Common - hypothetical protein ECA0095 25 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 50122235 Common mrcB penicillin-binding protein 1b ECA3313 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 50120717 Common bssS biofilm formation regulatory protein BssS ECA1784 11 None None None 50120685 Common sulA SOS cell division inhibitor ECA1752 14 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 50121993 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase ECA3070 216 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 50119755 Common - putative TonB-dependent ferrichrome receptor ECA0811 124 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 50120052 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase ECA1113 51 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 50120410 Common - hypothetical protein ECA1471 6 None None None 50122336 Common - hypothetical protein ECA3412 11 None None None 50121933 Common - ABC transporter ATP-binding protein ECA3010 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 50119684 Common budR LysR-family transcriptional regulator ECA0739 190 COG0583 LysR, Transcriptional regulator Transcription 50121745 Pathogen - hypothetical protein ECA2821 1 None None None 50121374 Common - hypothetical protein ECA2447 61 COG2850 COG2850, Uncharacterized conserved protein Function unknown 50119735 Common - putative lipoprotein ECA0790 3 COG5461 COG5461, Type IV pili component Cell motility and secretion 50119708 Common fldB flavodoxin FldB ECA0763 68 COG0716 FldA, Flavodoxins Energy production and conversion 50121434 Common - hypothetical protein ECA2510 29 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 50120840 Common - hypothetical protein ECA1910 12 None None None 50119171 Common trkH potassium transporter ECA0211 142 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 50122012 Pathogen - hypothetical protein ECA3089 1 None None None 50122344 Common - hypothetical protein ECA3420 2 None None None 50119212 Common - hypothetical protein ECA0252 35 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 50122734 Common ftsQ cell division protein FtsQ ECA3812 75 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 50119243 Common rnk nucleoside diphosphate kinase regulator ECA0283 73 COG0782 GreA, Transcription elongation factor Transcription 50118987 Common engB GTPase EngB ECA0022 177 COG0218 COG0218, Predicted GTPase General function prediction only 50120843 Common - ABC transporter, permease protein ECA1913 81 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50122018 Common - ABC transporter permease protein ECA3095 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50119103 Common slmA nucleoid occlusion protein ECA0142 49 COG1309 AcrR, Transcriptional regulator Transcription 50119318 Common exbD biopolymer transport protein ExbD ECA0359 138 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 50121287 Common - hypothetical protein ECA2359 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 50120078 Common cyoE protoheme IX farnesyltransferase ECA1139 190 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 50119471 Common - hypothetical protein ECA0520 23 None None None 50120003 Common - hypothetical protein ECA1063 6 None None None 50120241 Common mrdB cell wall shape-determining protein ECA1302 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 50121354 Common ogl oligogalacturonate lyase ECA2426 14 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 50122585 Common dnaB replicative DNA helicase ECA3664 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 50120516 Common - putative transposase (partial) ECA1582 6 None None None 50120339 Common - putative nucleoside H+ symporter ECA1400 66 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 50120376 Common rfbN O antigen biosynthesis rhamnosyltransferase rfbn ECA1437 44 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 50120482 Common amn AMP nucleosidase ECA1547 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 50122787 Common - hypothetical protein ECA3866 52 COG2966 COG2966, Uncharacterized conserved protein Function unknown 50122357 Common - hypothetical protein ECA3434 11 None None None 50121761 Common moeB molybdopterin biosynthesis protein MoeB ECA2837 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 50122141 Common hisS histidyl-tRNA synthetase ECA3219 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50122959 Common dsrH putative intracellular sulfur oxidation protein ECA4039 28 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 50121647 Common lysP lysine transporter ECA2723 172 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 50119313 Common metC cystathionine beta-lyase ECA0354 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 50123035 Common - TonB-dependent siderophore receptor ECA4115 98 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50123167 Common - ABC transporter permease protein ECA4247 177 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 50120647 Common fliR flagellar biosynthesis protein FliR ECA1714 117 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 50123025 Common hslO Hsp33-like chaperonin ECA4105 140 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 50120574 Pathogen - hypothetical protein ECA1642 1 None None None 50121254 Common adhE aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase and acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase ECA2326 190 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 50123326 Common - PTS system EIIc component ECA4408 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 50122205 Common rseA anti-RNA polymerase sigma factor SigE ECA3283 31 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 50121416 Common ruvB Holliday junction DNA helicase B ECA2491 226 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 50122487 Common eno phosphopyruvate hydratase ECA3566 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 50120036 Common - putative type I secretion protein, ATP-binding protein ECA1097 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 50121941 Common nuoL NADH dehydrogenase subunit L ECA3018 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 50121030 Pathogen hrpV type III secretion protein ECA2102 1 None None None 50119656 Pathogen - hypothetical protein ECA0709 1 None None None 50123206 Pathogen - hypothetical protein ECA4286 1 None None None 50119501 Common - hypothetical protein ECA0552 16 None None None 50120138 Common nrdA ribonucleotide-diphosphate reductase subunit alpha ECA1199 206 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 50122878 Common - probable transporter ECA3958 111 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50123056 Common malP maltodextrin phosphorylase ECA4136 142 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 50119894 Pathogen - hypothetical protein ECA0952 1 None None None 50122006 Common vacJ lipoprotein ECA3083 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 50120425 Common - non-ribosomal peptide synthetase ECA1487 224 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50121172 Common ddc L-2,4-diaminobutyrate decarboxylase ECA2244 110 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 50120998 Common - major facilitator family transporter ECA2070 102 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119612 Pathogen - hypothetical protein ECA0664 1 COG0583 LysR, Transcriptional regulator Transcription 50119010 Common pitA low-affinity inorganic phosphate transporter ECA0048 146 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 50119033 Common - putative monooxygenase ECA0071 124 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 50119325 Common - hypothetical protein ECA0366 14 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 50121176 Common - mannosyl-3-phosphoglycerate phosphatase ECA2248 30 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 50121326 Common - predicted hydrolase ECA2398 186 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 50119557 Common cfa2 coronafacic acid dehydratase ECA0607 168 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 50120837 Common - DeoR-family transcriptional regulator ECA1907 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 50122437 Common - predicted methyltransferase ECA3516 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 50122289 Common alaS alanyl-tRNA synthetase ECA3367 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50121341 Common - hypothetical protein ECA2413 44 COG2510 COG2510, Predicted membrane protein Function unknown 50122136 Common - probable short chain dehydrogenase ECA3214 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50121717 Common - hypothetical protein ECA2793 9 None None None 50120688 Common - hypothetical protein ECA1755 41 COG3304 COG3304, Predicted membrane protein Function unknown 50121105 Common - prophage integrase (partial) ECA2178 72 None None None 50121568 Common serS seryl-tRNA synthetase ECA2644 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 50122383 Common - phage integrase ECA3460 122 COG0582 XerC, Integrase DNA replication, recombination, and repair 50122766 Common thiP thiamin transporter membrane protein ECA3845 187 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 50122649 Common - conserved phage-related protein ECA3728 6 None None None 50122375 Common fic cell filamentation protein ECA3452 39 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 50122928 Common rpsK 30S ribosomal protein S11 ECA4008 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 50120364 Common hpcH putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase ECA1425 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 50122343 Pathogen - conserved hypothetical protei ECA3419 2 None None None 50121359 Common - two-component response regulator ECA2431 125 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 161501876 Pathogen asr acid shock protein precursor ECA2011 1 None None None 50119193 Common thiC thiamine biosynthesis protein ThiC ECA0232 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 50121694 Common glnQ glutamine ABC transporter ATP-binding protein ECA2770 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50120674 Common phoH hypothetical protein ECA1741 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 50122918 Common smf hypothetical protein ECA3998 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 50120100 Common amtB ammonium transporter ECA1161 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 50119565 Common - AraC-family transcriptional regulator ECA0615 62 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50119855 Common - putative component of polysulfide reductase ECA0913 20 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 50119047 Common - hypothetical protein ECA0086 12 None None None 50120451 Common - putative lipoprotein ECA1516 120 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 50119401 Common rhaT L-rhamnose-proton symport ECA0450 14 None None None 50120867 Common pdxY pyridoxamine kinase ECA1937 61 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 50123283 Common - hypothetical protein ECA4363 19 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50121248 Common oppF oligopeptide transport ATP-binding protein ECA2320 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 50121072 Common - putative substrate-binding periplasmic transport protein ECA2144 111 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 50123372 Common hmsH predicted outer membrane protein ECA4454 19 None None None 50121656 Common - elongation factor P ECA2732 215 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 50122761 Common - hypothetical protein ECA3840 8 None None None 50123361 Common rpmH 50S ribosomal protein L34 ECA4443 195 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 50119114 Common kdtX lipopolysaccharide core biosynthesis glycosyl transferase ECA0153 153 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 50119947 Common - probable ABC transporter, permease protein ECA1007 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50120802 Common - putative porin ECA1872 22 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 50121447 Common - hypothetical protein ECA2523 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 50122491 Common rumA 23S rRNA 5-methyluridine methyltransferase ECA3570 202 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 50123368 Common - hypothetical protein ECA4450 133 COG1733 COG1733, Predicted transcriptional regulators Transcription 50120524 Common - hypothetical protein ECA1590 24 COG3070 TfoX, Regulator of competence-specific genes Transcription 50122914 Common - hypothetical protein ECA3994 13 None None None 50122599 Pathogen - hypothetical protein ECA3678 1 None None None 50120252 Common gltJ glutamate/aspartate transport system permease protein ECA1313 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50120289 Common - putative hydrolase-oxidase ECA1350 122 COG0327 COG0327, Uncharacterized conserved protein Function unknown 50119400 Common - hypothetical protein ECA0449 16 COG3477 COG3477, Predicted periplasmic/secreted protein Function unknown 50119051 Common - hypothetical protein ECA0090 13 None None None 50122923 Common mscL large-conductance mechanosensitive channel ECA4003 138 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 50121399 Common ftnA ferritin ECA2473 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 50122420 Common - amidase ECA3499 223 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 50122758 Common - AraC-family transcriptional regulator ECA3837 95 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 50121170 Common - hypothetical protein ECA2242 14 None None None 50120414 Pathogen - hypothetical protein ECA1476 3 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 50119680 Common rsmC 16S ribosomal RNA m2G1207 methyltransferase ECA0735 121 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 50122431 Common - predicted inner membrane protein ECA3510 8 None None None 50120993 Common - N-acylamino acid racemase ECA2065 137 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50121344 Common ihfA integration host factor subunit alpha ECA2416 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 50121963 Common pta phosphate acetyltransferase ECA3040 173 COG0280 Pta, Phosphotransacetylase Energy production and conversion 50121746 Common bioD dithiobiotin synthetase ECA2822 160 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 50120846 Common - hypothetical protein ECA1916 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 50118977 Common rbsC ribose ABC transporter permease protein ECA0012 132 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 50120428 Common lacZ beta-D-galactosidase ECA1490 69 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 50122458 Common - amino acid-binding protein ECA3537 159 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50120902 Common sapD peptide transport system ATP-binding protein ECA1974 249 COG4170 SapD, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 50121087 Common hpaC putative 4-hydroxyphenylacetate 3-monooxygenase, reductase component ECA2159 108 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 50122238 Common sfsA sugar fermentation stimulation protein A ECA3316 106 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 50120472 Common hasA extracellular heme-binding protein ECA1537 3 None None None 50119596 Common uxaA altronate hydrolase ECA0647 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 50119550 Common cfa8B putative oxidoreductase ECA0600 177 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 50121876 Common nifY nitrogen fixation protein ECA2952 22 None None None 50122287 Common - predicted hydrolase ECA3365 181 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 50122609 Common - hypothetical protein ECA3688 134 COG0432 COG0432, Uncharacterized conserved protein Function unknown 50122130 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein ECA3208 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 50120234 Common crcB hypothetical protein ECA1295 109 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 50122909 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein ECA3989 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 50122581 Common - tRNA-dihydrouridine synthase A ECA3660 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 50120128 Common - putative GTP-binding protein YjiA ECA1189 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 50120056 Common - probable peroxidase ECA1117 219 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 50121663 Common - putative ABC-transporter, ATP-binding protein ECA2739 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 50121936 Common treB trehalose(maltose)-specific PTS system components IIBC ECA3013 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50120062 Common secF preprotein translocase subunit SecF ECA1123 220 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 50122274 Common aroF phospho-2-dehydro-3-deoxyheptonate aldolase ECA3352 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 50122314 Common - DnaG primase-like protein ECA3390 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50123336 Common dgoK 2-dehydro-3-deoxygalactonokinase ECA4418 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 50122384 Common - hypothetical protein ECA3461 4 None None None 50120830 Common narQ nitrate/nitrite sensor protein NarQ ECA1900 151 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 50120454 Common cbl transcriptional regulator CysB-like protein ECA1519 163 COG0583 LysR, Transcriptional regulator Transcription 50121425 Pathogen - putative DNA-binding protein ECA2500 3 None None None 50120270 Pathogen - hypothetical protein ECA1331 1 None None None 50122595 Pathogen - hypothetical protein ECA3674 3 None None None 50120245 Common nadD nicotinic acid mononucleotide adenyltransferase ECA1306 175 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 50121408 Common - hypothetical protein ECA2483 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 50123123 Common wzxE enterobacterial common antigen (ECA) biosynthesis protein ECA4203 22 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 50120168 Common hybD predicted maturation element for hydrogenase 2 ECA1229 68 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 50122880 Common - putative hydrolase ECA3960 117 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 50121388 Common - hypothetical protein ECA2462 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 50119645 Common rrmJ 23S rRNA methyltransferase J ECA0697 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 50120715 Common - hypothetical protein ECA1782 117 COG2353 COG2353, Uncharacterized conserved protein Function unknown 50118967 Common asnC DNA-binding transcriptional regulator AsnC ECA0002 138 COG1522 Lrp, Transcriptional regulators Transcription 50121080 Common - hypothetical protein ECA2152 143 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 50121643 Common - ABC transporter, ATP-binding protein ECA2719 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 50121781 Pathogen - hypothetical protein ECA2857 1 None None None 50120866 Common tyrS tyrosyl-tRNA synthetase ECA1936 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50119174 Common birA biotin--protein ligase ECA0214 216 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 50120315 Common - hypothetical protein ECA1376 47 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 50121028 Common hrcC type III secretion protein ECA2100 132 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 50119426 Common - TonB-dependent siderophore receptor protein ECA0475 131 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 50120011 Common - hypothetical protein ECA1071 10 None None None 50121859 Common - hypothetical protein ECA2935 27 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 50120022 Common phnA probable phosphonoacetate hydrolase ECA1082 102 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 50121691 Common dps DNA starvation/stationary phase protection protein Dps ECA2767 126 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 50121319 Common - cold shock-like protein cspC ECA2391 180 COG1278 CspC, Cold shock proteins Transcription 50122440 Common - putative acyl-CoA synthetase ECA3519 145 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 50119158 Common ubiB putative ubiquinone biosynthesis protein UbiB ECA0198 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 50121358 Common - hypothetical protein ECA2430 113 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119652 Common - putative degenerate non-ribosomal peptide synthetase (partial) ECA0705 26 None None None 50120047 Common sbcC exonuclease ECA1108 126 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 50122735 Common ddl D-alanine--D-alanine ligase ECA3813 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 50121392 Common - hypothetical protein ECA2466 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 50122586 Common alr alanine racemase ECA3665 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 50122875 Common - ABC transporter protein, membrane protein ECA3955 187 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50121771 Common - hypothetical protein ECA2847 11 None None None 50122953 Common bfr bacterioferritin, iron storage and detoxification protein ECA4033 107 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 50120104 Common hha hemolysin expression-modulating protein ECA1165 12 None None None 50119648 Common glmM phosphoglucosamine mutase ECA0700 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 50123046 Common ansB2 L-asparaginase II ECA4126 131 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 50121214 Common topA DNA topoisomerase I ECA2286 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 50120342 Common - 6-phosphogluconolactonase ECA1403 55 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 50119705 Common - hypothetical protein ECA0760 11 None None None 50119044 Common - hypothetical protein ECA0083 130 COG0730 COG0730, Predicted permeases General function prediction only 50122614 Common - hypothetical protein ECA3693 84 COG2128 COG2128, Uncharacterized conserved protein Function unknown 50122160 Common - DNA-binding transcriptional repressor ECA3238 173 COG1959 COG1959, Predicted transcriptional regulator Transcription 50123371 Common hmsF putative hemin storage lipoprotein ECA4453 83 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 50119494 Pathogen - alternative C-terminus for the PilV protein (fragment) ECA0545A 1 None None None 50122724 Common coaE dephospho-CoA kinase ECA3802 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 50122785 Common folA dihydrofolate reductase ECA3864 142 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 50121658 Common - putative membrane-bound phosphatase ECA2734 15 None None None 50122334 Pathogen - hypothetical protein ECA3410 2 None None None 50120192 Common purN phosphoribosylglycinamide formyltransferase ECA1253 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 50119153 Common argB acetylglutamate kinase ECA0193 212 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 50119714 Common - probable transporter ECA0769 141 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50122578 Common - hypothetical protein ECA3657 5 None None None 50122169 Common - hypothetical protein ECA3247 41 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 50123325 Common - putative glycosyl hydrolase ECA4407 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50121458 Common uup ABC transporter ATPase component ECA2534 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 50122020 Common - monooxygenase ECA3097 64 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 50121978 Common folC bifunctional folylpolyglutamate synthase/ dihydrofolate synthase ECA3055 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 50121152 Pathogen - hypothetical protein ECA2225A 1 None None None 50119065 Common argG argininosuccinate synthase ECA0104 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 50122539 Pathogen - hypothetical protein ECA3618 1 None None None 50119312 Common - putative DedA-family membrane protein ECA0353 153 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 50121035 Pathogen - putative lipoprotein ECA2107 3 None None None 50121223 Common - AraC-family transcriptional regulator ECA2295 61 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50122398 Common - hypothetical protein ECA3475 26 None None None 50122676 Common - putative calcineurin-like phosphoesterase ECA3754 8 COG1409 Icc, Predicted phosphohydrolases General function prediction only 50121125 Pathogen - putative lipoprotein ECA2199 4 None None None 50122017 Common - ABC transporter ATP-binding protein ECA3094 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 50121908 Common xenA flavoprotein xenobiotic reductase ECA2984 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 50121565 Common - permease ECA2641 69 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 50119983 Common lpxA UDP-N-acetylglucosamine acyltransferase ECA1043 150 COG1043 LpxA, Acyl- acyl carrier protein 50122265 Common mltD predicted membrane-bound lytic murein transglycosylase D ECA3343 145 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 50122701 Common - hypothetical protein ECA3779 7 None None None 50119104 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase ECA0143 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 50121443 Common - hypothetical protein ECA2519 20 COG3102 COG3102, Uncharacterized protein conserved in bacteria Function unknown 50119751 Common actP acetate permease ECA0806 184 COG4147 DhlC, Predicted symporter General function prediction only 50122137 Common - putative transport protein ECA3215 123 COG0679 COG0679, Predicted permeases General function prediction only 50122965 Common pmrB sensor protein BasS/PmrB ECA4045 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50119186 Common - hypothetical protein ECA0226 5 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 50122641 Common - putative phage-related protein ECA3720 29 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 50119341 Common pyrB aspartate carbamoyltransferase catalytic subunit ECA0382 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 50118988 Common - hypothetical protein ECA0024 13 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 50122341 Pathogen - putative phage regulatory protein ECA3417 2 COG1396 HipB, Predicted transcriptional regulators Transcription 50121021 Pathogen hrpA type III secretion protein ECA2093 1 None None None 50121436 Common - hypothetical protein ECA2512 53 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 50123057 Common glpR DNA-binding transcriptional repressor ECA4137 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 50120953 Common chaC putative cation transport protein ECA2025 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 50121336 Common paeX pectin acetylesterase ECA2408 57 COG0657 Aes, Esterase/lipase Lipid metabolism 50122355 Common - putative virulence-associated protein ECA3432 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 50119218 Common prmA ribosomal protein L11 methyltransferase ECA0258 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 50121451 Common - predicted lipoprotein ECA2527 21 None None None 50122011 Pathogen - hypothetical protein ECA3088 2 None None None 50121712 Common - LysE-family translocator ECA2788 105 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50119489 Pathogen pilS putative type IV pilus prepilin ECA0541 1 None None None 50123200 Common - hypothetical protein ECA4280 5 None None None 50122206 Common rpoE RNA polymerase sigma factor RpoE ECA3284 172 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50122551 Common - hypothetical protein ECA3630 74 COG1872 COG1872, Uncharacterized conserved protein Function unknown 50120267 Common glnS glutaminyl-tRNA synthetase ECA1328 243 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 50121286 Common - putative aldolase ECA2358 26 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 50120645 Common flgK flagellar hook-associated protein FlgK ECA1711 109 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 50120745 Common - hypothetical protein ECA1814 21 COG3150 COG3150, Predicted esterase General function prediction only 50121314 Common manY PTS system, mannose-specific IIc component ECA2386 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 161501877 Common - ATP-dependent RNA helicase HrpA ECA2006 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 50119664 Common nlpI lipoprotein NlpI ECA0717 47 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 50122899 Common pgi glucose-6-phosphate isomerase ECA3979 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 50122464 Common cysD sulfate adenylyltransferase subunit 2 ECA3543 139 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 50120077 Common - probable transporter ECA1138 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50118997 Common - hypothetical protein ECA0034 13 None None None 50121143 Common srfC putative virulence factor ECA2217 14 COG4458 SrfC, Uncharacterized protein conserved in bacteria, putative virulence factor Function unknown 50119477 Common topB DNA topoisomerase III ECA0525 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 50122356 Common - hypothetical protein ECA3433 20 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 50122564 Common - GnaT-family acetyltransferase ECA3643 24 COG3153 COG3153, Predicted acetyltransferase General function prediction only 50119385 Common - methyl-accepting chemotaxis protein ECA0434 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50123411 Common - putative lipoprotein ECA4495 11 None None None 50119900 Common - hypothetical protein ECA0958 23 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 50121296 Common minC septum formation inhibitor ECA2368 85 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 50121040 Common hrpW type III effector protein ECA2112 13 None None None 50120538 Common arsR DNA-binding transcriptional repressor ECA1605 161 COG0640 ArsR, Predicted transcriptional regulators Transcription 50121501 Common citA two-component sensor kinase ECA2577 166 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 50119953 Common - putative lipoprotein ECA1013 13 None None None 50122449 Common - hypothetical protein ECA3528 95 COG1720 COG1720, Uncharacterized conserved protein Function unknown 50121651 Common fruA fructose-specific PTS system IIBC component ECA2727 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 50121926 Common fdhE formate dehydrogenase accessory protein FdhE ECA3002 41 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 50119015 Common - putative phosphodiesterase ECA0053 131 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 50120592 Pathogen - hypothetical protein ECA1660 1 None None None 50121676 Common - hypothetical protein ECA2752 7 COG3311 AlpA, Predicted transcriptional regulator Transcription 50123160 Common - hypothetical protein ECA4240 15 None None None 50121299 Common rnd ribonuclease D ECA2371 116 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 50119472 Pathogen - hypothetical protein ECA0521 1 None None None 50119195 Common nudC NADH pyrophosphatase ECA0234 106 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 50119805 Common rpiB ribose-5-phosphate isomerase B ECA0863 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 50123394 Common - amino acid ABC transporter, ATP-binding protein ECA4478 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50119829 Common macB macrolide-specific ABC-type efflux carrier ECA0887 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 50122838 Common speA arginine decarboxylase ECA3918 112 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 50119809 Common tpiA putative triosephosphate isomerase ECA0867 214 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 50120069 Common pgpA phosphatidylglycerophosphatase A ECA1130 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 50120152 Common menB naphthoate synthase ECA1213 179 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 50122211 Common ung uracil-DNA glycosylase ECA3289 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 50119250 Common - hypothetical protein ECA0290 46 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 50121576 Common aat leucyl/phenylalanyl-tRNA--protein transferase ECA2652 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 50120253 Common gltI glutamate and aspartate transporter subunit ECA1314 135 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50121322 Common yfeC chelated iron transport system membrane protein ECA2394 191 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 50120494 Common sftR LysR-family transcriptional regulator ECA1559 182 COG0583 LysR, Transcriptional regulator Transcription 50123109 Common hemD uroporphyrinogen-III synthase ECA4189 50 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 50119164 Common rfaH transcriptional activator RfaH ECA0204 32 COG0250 NusG, Transcription antiterminator Transcription 50123027 Common envZ osmolarity sensor protein ECA4107 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50123102 Common - hypothetical protein ECA4182 31 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 50122040 Common dat D-alanine aminotransferase ECA3117 199 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 50119896 Common - acetyltransferase ECA0954 32 COG0456 RimI, Acetyltransferases General function prediction only 50122147 Common - PTS system, alpha-glucoside-specific IIbc component ECA3225 51 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50123190 Common - hypothetical protein ECA4270 20 COG3152 COG3152, Predicted membrane protein Function unknown 50121757 Common - putative ABC transporter permease protein ECA2833 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122177 Common - two-component system response regulator ECA3255 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 50119128 Common tdh L-threonine 3-dehydrogenase ECA0168 211 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 50119209 Common - hypothetical protein ECA0249 16 COG4922 COG4922, Uncharacterized protein conserved in bacteria Function unknown 50120734 Common - probable aminodeoxychorismate lyase ECA1801 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 50121123 Common tnpA transposase transposon tn1721 (partial) ECA2197 37 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 50119468 Pathogen - hypothetical protein ECA0517 2 None None None 50121012 Pathogen hrpQ type III secretion protein ECA2084 3 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 50122438 Common trxC thioredoxin 2 ECA3517 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 50122401 Common - hypothetical protein ECA3478 10 COG4104 COG4104, Uncharacterized conserved protein Function unknown 50122894 Common - hypothetical protein ECA3974 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 50119339 Common - putative endoribonuclease ECA0380 186 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 50119327 Common - hypothetical protein ECA0368 2 None None None 50121662 Common - putative ABC transporter , permease protein ECA2738 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 50122055 Pathogen - putative lipoprotein ECA3132 1 None None None 50121187 Common - LysR-family transcriptional regulator ECA2259 186 COG0583 LysR, Transcriptional regulator Transcription 50121364 Common rdgB regulator of pectin lyase production ECA2437 12 COG5566 COG5566, Uncharacterized conserved protein Function unknown 50121307 Common - hypothetical protein ECA2379 126 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 50119231 Common cafA ribonuclease G ECA0271 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 50122699 Common - hypothetical protein ECA3777 22 COG3112 COG3112, Uncharacterized protein conserved in bacteria Function unknown 50123241 Common ugpA glycerol-3-phosphate transporter permease ECA4321 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 50120506 Common - arsR-family transcriptional regulator ECA1572 53 COG0640 ArsR, Predicted transcriptional regulators Transcription 50120220 Common - methyl-accepting chemotaxis protein ECA1281 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121250 Common oppC oligopeptide transport system permease protein ECA2322 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122710 Common aceF dihydrolipoamide acetyltransferase ECA3788 200 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 50122850 Common - hypothetical protein ECA3930 9 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 50120824 Common napH quinol dehydrogenase membrane component ECA1894 36 COG0348 NapH, Polyferredoxin Energy production and conversion 50121847 Common - putative NADH:flavin oxidoreductase ECA2923 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 50120101 Common tesB acyl-CoA thioesterase II ECA1162 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 50121772 Common - lLysR-family transcriptional regulator ECA2848 145 COG0583 LysR, Transcriptional regulator Transcription 50119092 Common - LysR-family transcriptional regulator ECA0131 182 COG0583 LysR, Transcriptional regulator Transcription 50119071 Common - hypothetical protein ECA0110 123 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50119776 Common - phage regulatory protein ECA0833 7 None None None 50119463 Common - hypothetical protein ECA0512 21 None None None 50120116 Common - hypothetical protein ECA1177 112 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 50123139 Common - LysR-family transcriptional regulator ECA4219 157 COG0583 LysR, Transcriptional regulator Transcription 50120026 Common - putative signaling protein ECA1086 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50122976 Common kefB glutathione-regulated potassium-efflux system protein KefB ECA4056 208 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 50121684 Common - hypothetical protein ECA2760 14 None None None 50119440 Common - putative 2-hydroxy-3-oxopropionate reductase ECA0489 111 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 50120423 Common - putative lipoprotein ECA1485 12 COG1359 COG1359, Uncharacterized conserved protein Function unknown 50120756 Common - hypothetical protein ECA1826 114 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 50121232 Pathogen - hypothetical protein ECA2304 1 None None None 50121349 Common infC translation initiation factor IF-3 ECA2421 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 50120602 Common - hypothetical protein ECA1669A 10 None None None 50121989 Common - hypothetical protein ECA3066 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 50122686 Common - probable sodium:solute symporter ECA3764 159 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 50120531 Common - hypothetical protein ECA1597 18 None None None 50120604 Pathogen - hypothetical protein ECA1671 2 None None None 50122003 Common - hypothetical protein ECA3080 15 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 50119872 Common - probable permease ECA0930 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50123076 Pathogen - hypothetical protein ECA4156 1 None None None 50123031 Common - probable transporter ECA4111 146 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119461 Common - putative capsular polysacharide biosynthesis transferase ECA0510 176 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 50120727 Common plsX fatty acid/phospholipid synthesis protein ECA1794 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 50123298 Common - probable sugar transporter ECA4380 206 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50120553 Common virB5 putative conjugal transfer protein ECA1619 9 None None None 50122005 Common mqo malate:quinone oxidoreductase ECA3082 56 COG0579 COG0579, Predicted dehydrogenase General function prediction only 50120571 Common - hypothetical protein ECA1639 19 COG3886 COG3886, Predicted HKD family nuclease DNA replication, recombination, and repair 50119822 Common - putative ABC transporter ATP-binding protein ECA0880 242 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 50122668 Common - ABC transporter, membrane spanning protein ECA3746 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 50121790 Common - hypothetical protein ECA2866 30 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 50123252 Common - methyl-accepting chemotaxis protein ECA4332 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50119029 Common - putative LysE family transporter ECA0067 112 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50121994 Common - hypothetical protein ECA3071 67 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 50122486 Common - TonB dependent receptor ECA3565 92 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50121599 Common potH putrescine transporter subunit: membrane component of ABC superfamily ECA2675 208 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 50120622 Common motB flagellar motor protein ECA1688 110 COG1360 MotB, Flagellar motor protein Cell motility and secretion 50120861 Common hor transcriptional regulator SlyA ECA1931 97 COG1846 MarR, Transcriptional regulators Transcription 50122854 Common hfq RNA-binding protein Hfq ECA3934 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 50119885 Common - fimbriae major subunit protein ECA0943 16 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 50119577 Common plsB glycerol-3-phosphate acyltransferase ECA0628 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 50123360 Pathogen - hypothetical protein ECA4442 1 None None None 50120819 Common ccmH1 cytochrome C-type biogenesis protein ECA1889 89 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 50120306 Common - hypothetical protein ECA1367 14 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 50119393 Common rhaR L-rhamnose operon transcriptional activator ECA0442 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50120362 Common rfbG CDP-glucose 4,6-dehydratase ECA1423 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50122194 Pathogen - hypothetical protein ECA3272 1 None None None 50120153 Common menC O-succinylbenzoate synthase ECA1214 58 COG1441 MenC, O-succinylbenzoate synthase Coenzyme metabolism 50119433 Common - putative non-ribosomal peptide synthetase ECA0482 207 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50122045 Common hsdR type I restriction enzyme EcoEI R protein ECA3122 137 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 50119412 Common - Z-ring-associated protein ECA0461 47 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 50122047 Pathogen - hypothetical protein ECA3124 4 None None None 50121767 Common - putative sodium:sulfate symporter ECA2843 86 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 50120546 Common virB11 putative conjugal transfer protein ECA1613 162 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 50122791 Common carB carbamoyl phosphate synthase large subunit ECA3870 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 50119976 Common uppS undecaprenyl pyrophosphate synthetase ECA1036 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 50119991 Common - hypothetical protein ECA1051 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 50119291 Common - hypothetical protein ECA0332 26 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 50121369 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase ECA2442 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 50121320 Common yfeA periplasmic chelated iron-binding protein ECA2392 177 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 50123225 Common sftR LysR-family transcriptional regulator ECA4305 187 COG0583 LysR, Transcriptional regulator Transcription 50120462 Common - putative malate/lactate dehydrogenase ECA1527 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 50122228 Common - hypothetical protein ECA3306 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 50122988 Common pelB pectate lyase II ECA4068 16 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 50122528 Common fklB peptidyl-prolyl cis-trans isomerase ECA3607 142 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 50120005 Common - hypothetical protein ECA1065 15 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 50120443 Common - formate dehydrogenase ECA1507 195 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 50122254 Common - hypothetical protein ECA3332 11 None None None 50123033 Common - putative cystathionine beta-synthase ECA4113 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 50120370 Common rfbX putative O-antigen transporter ECA1431 23 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 50119807 Common - probable transport protein ECA0865 129 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 50122418 Common - putative gamma-glutamyltranspeptidase ECA3497 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 50122985 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein ECA4065 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 50121521 Common pflB formate acetyltransferase ECA2597 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 50120150 Common menD 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase ECA1211 78 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 50121602 Common - hypothetical protein ECA2678 13 None None None 50119389 Common rhaD rhamnulose-1-phosphate aldolase ECA0438 31 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 50120979 Common - putitive ABC-transporter ATP-binding protein ECA2051 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50122079 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit ECA3157 192 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 50122259 Common nrdE ribonucleotide-diphosphate reductase subunit alpha ECA3337 213 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 50123098 Common - hypothetical protein ECA4178 56 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 50122592 Common - hypothetical protein ECA3671 39 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 50121849 Common - probable short chain dehydrogenase ECA2925 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50122213 Common gltX glutamyl-tRNA synthetase ECA3291 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 50119281 Common - hypothetical protein ECA0321 60 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 50121953 Common hexA1 LysR-family transcriptional regulator of motility and virulence ECA3030 180 COG0583 LysR, Transcriptional regulator Transcription 50122932 Common rplO 50S ribosomal protein L15 ECA4012 69 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 50122627 Common - putative phage-related DNA-binding protein ECA3706 9 COG1414 IclR, Transcriptional regulator Transcription 50120916 Common tyrR DNA-binding transcriptional dual regulator, tyrosine-binding ECA1989 172 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 50123245 Common - DeoR-family trancriptional regulator ECA4325 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 50120159 Common - putative thioredoxin ECA1220 218 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 50120893 Common - LysR-family transcriptional regulator ECA1965 178 COG0583 LysR, Transcriptional regulator Transcription 50121593 Common artQ arginine transporter permease subunit ArtQ ECA2669 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 50122098 Common malF maltose transport system permease protein ECA3176 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 50119519 Common - hypothetical protein ECA0570 21 None None None 50121824 Pathogen - hypothetical protein ECA2900 2 None None None 50122493 Common garK glycerate kinase 2 ECA3572 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 50120970 Pathogen - hypothetical protein ECA2042 2 None None None 50121826 Pathogen - hypothetical protein ECA2902 1 None None None 50121943 Common nuoJ NADH dehydrogenase subunit J ECA3020 99 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 50121632 Common - hypothetical protein ECA2708 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 50120380 Common rfbC dTDP-6-deoxy-D-glucose-3,5 epimerase ECA1441 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 50122050 Pathogen - acyl carrier protein ECA3127 3 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50123392 Common pstC phosphate transporter permease subunit ECA4476 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 50122781 Common apaG ApaG ECA3860 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 50119673 Common deoA thymidine phosphorylase ECA0728 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 50119512 Pathogen - hypothetical protein ECA0563 2 None None None 50123221 Common atsR putative sulfate ester binding protein ECA4301 78 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 50122509 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase ECA3588 190 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 50122066 Common - hypothetical protein ECA3143 19 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 50121894 Common - ABC-transporter ATP-binding protein ECA2970 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50121896 Common - putative hydrolase ECA2972 196 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 50119971 Common rpsB 30S ribosomal protein S2 ECA1031 224 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 50120923 Common col colicin ECA1996 4 None None None 50120396 Common - putative thiamine pyrophosphate-dependent protein ECA1457 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 50122757 Common - hypothetical protein ECA3836 109 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 50123420 Common - putative acyl carrier protein ECA4504 47 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50121193 Common - hypothetical protein ECA2265 23 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 50122993 Common - ABC transporter ATP binding protein ECA4073 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 50119666 Common - hypothetical protein ECA0721 51 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 50122929 Common rpsM 30S ribosomal protein S13 ECA4009 245 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 50123217 Common astB sulfate ester ABC transporter permease protein ECA4297 183 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50123382 Pathogen - hypothetical protein ECA4465 1 None None None 50121834 Pathogen - putative plasmid replication protein ECA2910 3 None None None 50121860 Common nifQ nitrogen fixation protein ECA2936 23 None None None 50122081 Common sdaB L-serine dehydratase 2 ECA3159 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 50121002 Common - hypothetical protein ECA2074 97 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 50119834 Common ptsI phosphoenolpyruvate-protein phosphotransferase ECA0892 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 50123007 Common trpS tryptophanyl-tRNA synthetase ECA4087 231 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50119136 Common - hypothetical protein ECA0176 25 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 50121635 Common folE GTP cyclohydrolase I ECA2711 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 50120208 Common - putative suppressor of the inhibitory activity of the carbon storage regulator CsrA ECA1269 143 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 50121508 Common hisC histidinol-phosphate aminotransferase ECA2584 235 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 50119910 Common - hypothetical protein ECA0970 29 COG5441 COG5441, Uncharacterized conserved protein Function unknown 50121055 Common - hypothetical protein ECA2127 3 None None None 50119686 Common budB acetolactate synthase ECA0741 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 50121237 Common - putative phage-related protein ECA2309 14 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 50123312 Common dppA periplasmic dipeptide transport protein ECA4394 211 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50119357 Common - putative hemagglutinin-like protein (partial) ECA0399A 7 None None None 50119219 Common panF sodium/panthothenate symporter ECA0259 176 COG4145 PanF, Na+/panthothenate symporter Coenzyme metabolism 50120331 Pathogen - hypothetical protein ECA1392 1 None None None 50123231 Common cpxR DNA-binding response regulator in two-component regulatory system with CpxA ECA4311 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50120139 Common ubiG 3-demethylubiquinone-9 3-methyltransferase ECA1200 174 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 50119919 Common - hypothetical protein ECA0979 15 None None None 50120804 Common - putative inosine-uridine preferring nucleoside hydrolase ECA1874 44 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 50123402 Common - hypothetical protein ECA4486 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 50122900 Pathogen - hypothetical protein ECA3980 1 None None None 50122117 Common - phosphate-starvation-inducible protein PsiE ECA3195 22 COG3223 COG3223, Predicted membrane protein Function unknown 50121903 Common - probable hydrolase ECA2979 69 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 50121372 Common pehR DNA-binding response regulator in two-component regulatory system with PhoQ ECA2445 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50123195 Common - hypothetical protein ECA4275 29 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 50122163 Common - ABC transporter, substrate binding protein ECA3241 70 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50121797 Pathogen - putative transcriptional regulator ECA2873 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50122411 Common amaB allantoate amidohydrolase ECA3490 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 50122179 Common - two-component system sensor kinase ECA3257 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50121924 Common - hypothetical protein ECA3000 19 COG2149 COG2149, Predicted membrane protein Function unknown 50123277 Pathogen - putative lipoprotein ECA4357 3 None None None 50123294 Common - hypothetical protein ECA4376 40 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 50119470 Common - replicative DNA helicase ECA0519 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 50123311 Common dppB dipeptide transporter permease DppB ECA4393 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50119617 Pathogen - hypothetical protein ECA0669 1 None None None 50120810 Common nrfF formate-dependent nitrite reductase complex subunit NrfF ECA1880 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 50119290 Common nudF ADP-ribose pyrophosphatase NudF ECA0331 68 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 50119961 Common syd SecY interacting protein Syd ECA1021 19 None None None 50123085 Common glpA sn-glycerol-3-phosphate dehydrogenase subunit A ECA4165 165 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 50120983 Common - putative transport system, periplasmic solute-binding protein ECA2055 71 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 50121145 Common srfA putative virulence effector protein ECA2219 13 COG5373 COG5373, Predicted membrane protein Function unknown 50120173 Common hypB hydrogenase nickel incorporation protein HypB ECA1234 110 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 50121574 Common cydD cysteine/glutathione ABC transporter membrane/ATP-binding component ECA2650 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 50120630 Common flhB flagellar biosynthesis protein FlhB ECA1696 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 50122154 Common fdx ferredoxin, 2Fe-2S ECA3232 107 COG0633 Fdx, Ferredoxin Energy production and conversion 50120142 Common rcsB DNA-binding response regulator in two-component regulatory system with RcsC and YojN ECA1203 172 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50120888 Common araD L-ribulose-5-phosphate 4-epimerase ECA1960 102 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 50122745 Common mraW S-adenosyl-methyltransferase MraW ECA3823 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 50122542 Common - 23S rRNA (guanosine-2'-O-)-methyltransferase ECA3621 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 50123074 Common - putative transcriptional regulator ECA4154 6 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 50122818 Common gpmB phosphoglycerate mutase ECA3897 158 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 50123209 Common - hypothetical protein ECA4289 5 None None None 50121584 Common - hypothetical protein ECA2660 26 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 50120794 Common sufE cysteine desufuration protein SufE ECA1864 94 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 50120501 Common - hypothetical protein ECA1566 35 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 50121616 Common - putative flavin-containing amine oxidase ECA2692 67 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 50123273 Common sirA cell developmental protein SirA ECA4353 100 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 50120292 Common - hypothetical protein ECA1353 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 50119761 Pathogen - hypothetical protein ECA0818 1 None None None 50119090 Common - putative deoxycytidylate deaminase ECA0129 58 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 50122844 Common gshB glutathione synthetase ECA3924 127 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 50119459 Common - hypothetical protein ECA0508 8 None None None 50120784 Common apbE thiamine biosynthesis lipoprotein ApbE ECA1854 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 50119311 Common - AraC-family trancriptional regulator ECA0352 99 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 161501879 Common - putrescine--2-oxoglutarate aminotransferase ECA1543 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 50120642 Common flgH flagellar basal body L-ring protein ECA1708 97 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 50119099 Common - ABC transporter ATP-binding protein ECA0138 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 50120038 Common - large repetitive protein ECA1099 126 None None None 50123355 Common - MFS efflux transporter ECA4437 133 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50122796 Common lspA lipoprotein signal peptidase ECA3875 182 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50119269 Common sspB ClpXP protease specificity-enhancing factor ECA0309 64 COG2969 SspB, Stringent starvation protein B General function prediction only 50120693 Common - hypothetical protein ECA1760 43 COG3785 COG3785, Uncharacterized conserved protein Function unknown 50119582 Common - hypothetical protein ECA0633 96 COG1741 COG1741, Pirin-related protein General function prediction only 50122297 Common - probable transporter ECA3375 73 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122515 Common - hypothetical protein ECA3594 28 COG2105 COG2105, Uncharacterized conserved protein Function unknown 50119629 Common dnaG DNA primase ECA0681 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50121302 Common - hypothetical protein ECA2374 157 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 50119523 Pathogen - hypothetical protein ECA0574 3 None None None 50122094 Common galR DNA-binding transcriptional repressor ECA3172 128 COG1609 PurR, Transcriptional regulators Transcription 50120935 Common - putative signaling protein ECA2008 167 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 50121246 Common cls cardiolipin synthetase ECA2318 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 50120097 Common mdlA putative multidrug transporter membrane\ATP-binding components ECA1158 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 50121880 Common nifH nitrogenase iron protein ECA2956 80 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 50119200 Common purD phosphoribosylamine--glycine ligase ECA0240 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 50120928 Common aer1 aerotaxis receptor ECA2001 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121751 Common celB beta(1,4)-glucan glucanohydrolase ECA2827 10 None None None 50119725 Common - hypothetical protein ECA0780 15 None None None 50120872 Common - putative periplasmic oligopeptide-binding protein ECA1942 211 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 50122386 Common proB gamma-glutamyl kinase ECA3463 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 50123301 Common uxaB2 altronate oxidoreductase ECA4383 82 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 50120879 Common - putative transketolase C-terminal section ECA1951 222 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 50121398 Common - hypothetical protein ECA2472 11 None None None 50119303 Common - hypothetical protein ECA0344 6 None None None 50120353 Common dcuC C4-dicarboxylate transporter DcuC ECA1414 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 50120618 Common - hypothetical protein ECA1684 118 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 50123287 Common - hypothetical protein ECA4367 7 None None None 50121986 Common fabB 3-oxoacyl-(acyl carrier protein) synthase I ECA3063 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50119525 Common - hypothetical protein ECA0576 18 None None None 50122324 Common - DnaG primase-like protein ECA3400 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50123013 Common aroK shikimate kinase I ECA4093 201 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 50121167 Common - hypothetical protein ECA2239 36 COG4628 COG4628, Uncharacterized conserved protein Function unknown 50122828 Common iciA chromosome replication initiation inhibitor protein ECA3907 74 COG0583 LysR, Transcriptional regulator Transcription 50120710 Common mdoG glucan biosynthesis protein G ECA1777 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 50121487 Common - putative iron ABC transporter, permease component ECA2563 190 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 50120765 Common nlpC probable lipoprotein ECA1835 137 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 50123417 Common - putative AMP-binding enzyme ECA4501 79 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 50120582 Pathogen - hypothetical protein ECA1650 1 None None None 50120775 Common hmuT hemin-binding periplasmic protein ECA1845 133 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 50119923 Common - hypothetical protein ECA0983 124 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 50119567 Common - putative transcriptional regulator ECA0617 29 COG1309 AcrR, Transcriptional regulator Transcription 50120433 Common uhpC putative regulatory protein ECA1495 107 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50121887 Common - ABC transporter, substrate binding protein ECA2963 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50120278 Common kdpD sensor protein KdpD ECA1339 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 50122662 Common - putative bacteriophage tail fiber protein ECA3740 9 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 50121624 Pathogen - hypothetical protein ECA2700 1 None None None 50119843 Common norW nitric oxide reductase ECA0901 242 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 50120658 Common fliG flagellar motor switch protein G ECA1725 124 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 50122405 Common - hypothetical protein ECA3482 2 None None None 50122907 Common metH B12-dependent methionine synthase ECA3987 177 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 50119864 Common - LysR-family transcriptional regulator ECA0922 170 COG0583 LysR, Transcriptional regulator Transcription 50121965 Common - putative NUDIX hydrolase ECA3042 22 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 50120467 Common - putative aspartate racemase ECA1532 77 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 50119692 Common - short chain dehydrogenase ECA0747 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50120217 Common - conserved hypothetical protein (partial) ECA1278 23 COG3910 COG3910, Predicted ATPase General function prediction only 50119457 Common - probable capsular polysaccharide bisynthesis glycosyl transferase ECA0506 188 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 50120744 Common nagZ beta-hexosaminidase ECA1813 178 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 50119375 Common - hypothetical protein ECA0424 95 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 50123142 Common ilvY DNA-binding transcriptional regulator IlvY ECA4222 186 COG0583 LysR, Transcriptional regulator Transcription 50119853 Common - hypothetical protein ECA0911 7 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 50121273 Common - putative aldose 1-epimerase ECA2345 59 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 50121727 Common - hypothetical protein ECA2803 32 COG5654 COG5654, Uncharacterized conserved protein Function unknown 50121091 Common - autotransporter ECA2163 56 COG5571 COG5571, Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion Cell motility and secretion 50121180 Common - L-allo-threonine dehydrogenase, NAD(P)-binding ECA2252 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 50122656 Common - putative bacteriophage tail fibre protein ECA3734 6 None None None 50120442 Common citM citrate transporter ECA1506 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 50122348 Common - putative lipoprotein ECA3424 47 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 50119482 Common pilL putative Type IV pilus protein ECA0532 24 None None None 50120955 Common - putative acyltransferase ECA2027 22 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 50122366 Common - hypothetical protein ECA3443 13 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 50123173 Common metJ transcriptional repressor protein MetJ ECA4253 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 50119598 Common - putative DNA mismatch repair protein ECA0649 15 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 50120071 Common ispA geranyltranstransferase ECA1132 239 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 50119942 Common - putative dihydrodipicolinate synthase ECA1002 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 50121382 Pathogen - probable transcriptional regulator (partial) ECA2456 2 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50120474 Common - putative transmembrane sensor protein ECA1539 48 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 50118979 Common rbsK ribokinase ECA0014 181 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 50122033 Common outC general secretion pathway protein C ECA3110 17 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 50121164 Common - hypothetical protein ECA2236 21 None None None 50122376 Pathogen - putative phage capsid protein (partial) ECA3453 1 None None None 50120565 Common - hypothetical protein ECA1633 7 None None None 50122708 Common - hypothetical protein ECA3786 5 None None None 50120941 Common - hypothetical protein ECA2014 4 None None None 50121778 Common - hypothetical protein ECA2854 10 None None None 50120287 Common - hypothetical protein ECA1348 70 COG3272 COG3272, Uncharacterized conserved protein Function unknown 50121540 Common - putative phage encoded host lysis, regulatory protein ECA2615 8 None None None 50121665 Common bcr bicyclomycin/multidrug efflux system ECA2741 216 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120526 Common - putative acetyl-hydrolase ECA1592 126 COG0657 Aes, Esterase/lipase Lipid metabolism 50119271 Common gltD glutamate synthase subunit beta ECA0311 213 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 50119483 Pathogen pilM putative Type IV pilus protein ECA0533 3 None None None 50119928 Common thyA thymidylate synthase ECA0988 139 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 50120318 Common pnuC nicotinamide mononucleotide transport protein ECA1379 62 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 50123302 Common eamA probable amino acid metabolite efflux pump ECA4384 115 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 50119308 Common dkgA 2,5-diketo-D-gluconate reductase A ECA0349 186 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 50120334 Common modC molybdate transporter ATP-binding protein ECA1395 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 50123116 Common - putative acetyltransferase ECA4196 7 COG0456 RimI, Acetyltransferases General function prediction only 50119260 Common - putative bolA family protein ECA0300 76 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 50121914 Common nasA nitrate reductase ECA2990 189 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 50121132 Common - universal stress protein UspE ECA2206 48 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 50121423 Common - hypothetical protein ECA2498 69 COG1801 COG1801, Uncharacterized conserved protein Function unknown 50121768 Common - hypothetical protein ECA2844 7 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 50123072 Common - putative two-component system sensor kinase ECA4152 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 50121707 Common prtD protease secretion ATP-binding protein ECA2783 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 50121213 Pathogen - hypothetical protein ECA2285 1 None None None 50120829 Pathogen - hypothetical protein ECA1899 1 None None None 50121400 Common holE DNA polymerase III subunit theta ECA2475 12 None None None 50119002 Common rpoZ DNA-directed RNA polymerase subunit omega ECA0039 110 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 50120652 Common fliM flagellar motor switch protein FliM ECA1719 110 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 50123338 Common - ABC transporter ATP-binding protein ECA4420 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 50121259 Common expL hypothetical protein ECA2331 133 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 50121605 Common grxA glutaredoxin 1 ECA2681 51 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 50120856 Common - hypothetical protein ECA1926 130 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 50119589 Common - hypothetical protein ECA0640 18 None None None 50119945 Common - ABC transporter, ATP-binding protein ECA1005 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 50119151 Common argE acetylornithine deacetylase ECA0191 204 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 50122999 Common nirB nitrite reductase [NAD(P)H] large subunit ECA4079 193 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 50122865 Pathogen - hypothetical protein ECA3945 1 None None None 50119693 Common - putative binding-protein-dependent transport system protein ECA0748 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 50121418 Common ruvC Holliday junction resolvase ECA2493 194 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 50120311 Common tolA cell envelope integrity inner membrane protein TolA ECA1372 14 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 50119535 Pathogen - hypothetical protein ECA0586 1 None None None 50120753 Common lolC outer membrane-specific lipoprotein transporter subunit LolC ECA1823 166 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 50118970 Common - hypothetical protein ECA0005 80 COG0714 COG0714, MoxR-like ATPases General function prediction only 50120851 Common - L-lactate permease ECA1921 104 COG1620 LldP, L-lactate permease Energy production and conversion 50121737 Common MoaE molybdopterin synthase large subunit ECA2813 151 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 50121101 Common - hypothetical protein ECA2173 104 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 50122101 Common pbg beta-galactosidase ECA3179 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 50121389 Common - hypothetical protein ECA2463 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 50119428 Common entC isochorismate synthase ECA0477 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50123184 Common menG ribonuclease activity regulator protein RraA ECA4264 77 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 50120190 Common hypF hydrogenase maturation protein ECA1251 113 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 50122573 Common lysA diaminopimelate decarboxylase ECA3652 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 50119329 Common - hypothetical protein ECA0370 78 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122873 Common - probable transporter ECA3953 69 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 50120681 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase ECA1748 85 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 50119314 Common - putative DedA-family membrane protein ECA0355 135 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 50122955 Common tuf elongation factor Tu ECA4035 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 50121345 Common pheT phenylalanyl-tRNA synthetase subunit beta ECA2417 244 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 50121127 Common - putative integrase ECA2201 41 None None None 50120269 Common fldA flavodoxin FldA ECA1330 73 COG0716 FldA, Flavodoxins Energy production and conversion 50121225 Common trpG anthranilate synthase component II ECA2297 231 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 50119042 Common - hypothetical protein ECA0081 48 COG0456 RimI, Acetyltransferases General function prediction only 50120018 Common fecR regulator for fec operon FecR ECA1078 45 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 50121438 Pathogen - hypothetical protein ECA2514 4 None None None 50120081 Common cyoB cytochrome O ubiquinol oxidase subunit I ECA1142 163 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 50122304 Pathogen - putative bacteriocin immunity protein ECA3381A 1 None None None 50122588 Common - putative lipoprotein ECA3667 3 None None None 50123243 Pathogen - hypothetical protein ECA4323 2 None None None 50122719 Common nadC quinolinate phosphoribosyltransferase ECA3797 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 50123029 Common - hypothetical protein ECA4109 11 COG1475 Spo0J, Predicted transcriptional regulators Transcription 50123323 Common - hypothetical protein ECA4405 22 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 50122332 Pathogen - putative phage regulatory protein ECA3408 2 COG1396 HipB, Predicted transcriptional regulators Transcription 50122650 Common - major tail sheath protein ECA3729 45 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 50119732 Common - hypothetical protein ECA0787 2 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 50123162 Common sthA soluble pyridine nucleotide transhydrogenase ECA4242 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 50122162 Common suhB inositol monophosphatase ECA3240 215 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 50119130 Common - hypothetical protein ECA0170 186 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 50123296 Common - putative aminotransferase ECA4378 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 50120832 Common - AraC-family transcriptional regulator ECA1902 102 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50120988 Common - putative class-III aminotransferase ECA2060 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 50119293 Common - esterase YqiA ECA0334 49 COG3150 COG3150, Predicted esterase General function prediction only 50120419 Common - hypothetical protein ECA1481 7 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 50120357 Common wzb probable protein-tyrosine-phosphatase ECA1418 127 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 50119682 Common - LysR-family transcriptional regulator ECA0737 180 COG0583 LysR, Transcriptional regulator Transcription 50122209 Common srmB ATP-dependent RNA helicase SrmB ECA3287 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 50120961 Common narJ respiratory nitrate reductase 1 delta chain ECA2033 42 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 50123018 Common - hypothetical protein ECA4098 17 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 50120041 Common ansB1 L-asparaginase precursor ECA1102 122 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 50120360 Common rfbI CDP-6-deoxy-delta-3,4-glucoseen reductase ECA1421 150 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 50120891 Common rnb exoribonuclease II ECA1963 192 COG4776 Rnb, Exoribonuclease II Transcription 50121492 Common - hypothetical protein ECA2568 19 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 50123331 Common ssuB aliphatic sulfonates transport ATP-binding subunit ECA4413 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50119343 Common argI ornithine carbamoyltransferase subunit I ECA0384 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 50120075 Common panE 2-dehydropantoate 2-reductase ECA1136 107 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 50119184 Common rpoC DNA-directed RNA polymerase subunit beta' ECA0224 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 50119420 Common osmY periplasmic protein ECA0469 86 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 50122910 Common aceA isocitrate lyase ECA3990 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 50119659 Common infB translation initiation factor IF-2 ECA0712 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 50119882 Common - hypothetical protein ECA0940 10 None None None 50119591 Common - putative DedA-family membrane protein ECA0642 142 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 50121996 Common - hypothetical protein ECA3073 7 COG5430 COG5430, Uncharacterized secreted protein Function unknown 50122285 Common gshA glutamate--cysteine ligase ECA3363 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 50120344 Common - hypothetical protein ECA1405 35 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50122558 Pathogen - putative host cell surface-exposed lipoprotein ECA3637 1 None None None 50119810 Common - hypothetical protein ECA0868 9 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 50122783 Common - hypothetical protein ECA3862 63 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 50121338 Common - putative sodium:dicarboxylate symporter ECA2410 154 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 50119216 Common - tRNA-dihydrouridine synthase B ECA0256 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 50120236 Common lipA lipoyl synthase ECA1297 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 50119830 Common macA macrolide-specific efflux protein maca precursor ECA0888 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50120903 Common sapC peptide transport system permease protein ECA1975 203 COG4171 SapC, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 50120948 Common - putative sulfate transporter YchM ECA2021 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 50121234 Common - probable phage integrase ECA2306 47 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50119750 Common - hypothetical protein ECA0805 31 COG5464 COG5464, Uncharacterized conserved protein Function unknown 50121179 Pathogen - hypothetical protein ECA2251 1 None None None 50122144 Common - hypothetical protein ECA3222 74 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 50120556 Common virB1 putative conjugal transfer protein ECA1622 25 None None None 50122353 Common - putative lipoprotein ECA3430 99 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 50119993 Common mutS DNA mismatch repair protein ECA1053 203 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 50119106 Common radC DNA repair protein RadC ECA0145 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 50121563 Common - putative hydantoinase ECA2639 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50123363 Common - putative inner membrane protein translocase component YidC ECA4445 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 50122643 Common - putative phage-related protein ECA3722 19 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 50122423 Common proV glycine betaine/L-proline transport ATP-binding protein ECA3502 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 50120369 Common - putative dTDP-glucose 4-6-dehydratase ECA1430 223 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50120740 Common - purine nucleoside phosphoramidase ECA1809 225 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 50120594 Pathogen - hypothetical protein ECA1662 1 None None None 50121945 Common nuoH NADH dehydrogenase subunit H ECA3022 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 50120258 Common - hypothetical protein ECA1319 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 50122569 Common - PTS system, cellobiose-specific IIa component ECA3648 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 50121284 Common - putative sugar phosphotransferase enzyme IIa component ECA2356 38 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 50123059 Common glpE thiosulfate sulfurtransferase ECA4139 120 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 50119407 Common - hypothetical protein ECA0456 25 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 50122433 Common emrA multidrug resistance protein A ECA3512 142 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 50122510 Common uppP undecaprenyl pyrophosphate phosphatase ECA3589 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 50119226 Common - regulatory protein CsrD ECA0266 143 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 50120243 Common - hypothetical protein ECA1304 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 50122746 Common mraZ hypothetical protein ECA3824 141 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 50121329 Common kduD 2-deoxy-D-gluconate 3-dehydrogenase ECA2401 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50121257 Common galU UTP--glucose-1-phosphate uridylyltransferase subunit GalU ECA2329 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 50119419 Common prfC peptide chain release factor 3 ECA0468 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 50120125 Common - hypothetical protein ECA1186 4 None None None 50122132 Common xseA exodeoxyribonuclease VII large subunit ECA3210 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 50119727 Pathogen - hypothetical protein ECA0782 1 None None None 50120385 Common - putative lipoprotein ECA1446 15 None None None 50119173 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase ECA0213 203 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 50122347 Pathogen - hypothetical protein ECA3423 2 None None None 50120771 Common - hypothetical protein ECA1841 13 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 50119739 Common - putative type IV pilus protein ECA0794 68 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 50119850 Common ada ADA regulatory protein (methylated-DNA--protein-cysteine methyltransferase) ECA0908 181 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 50119748 Common - hypothetical protein ECA0803 34 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50119119 Common waaI lipopolysaccharide 1,3-galactosyltransferase ECA0158 30 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 50121961 Common - hypothetical protein ECA3038 23 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 50123052 Common bioH putative biotin biosynthesis protein ECA4132 162 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 50123176 Common - putative iron(III) ABC transporter permease protein ECA4256 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50121938 Common - hypothetical protein ECA3015 10 COG4575 ElaB, Uncharacterized conserved protein Function unknown 50120226 Common citM Mg(2+)/citrate complex transporter ECA1287 34 COG2851 CitM, H+/citrate symporter Energy production and conversion 50119369 Common - hypothetical protein ECA0413 17 None None None 50120897 Common - putative NADH:flavin oxidoreductase ECA1969 235 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 50120231 Common - hypothetical protein ECA1292 105 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 50121653 Common fruB fructose-specific PTS IIA/HPr components ECA2729 120 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 50122925 Common rplQ 50S ribosomal protein L17 ECA4005 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 50121119 Common sirB2 hypothetical protein ECA2192 28 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 50119552 Common cfa7 type I polyketide synthase ECA0602 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50119017 Common prlC oligopeptidase A ECA0055 124 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 50122027 Common outI general secretion pathway protein I ECA3104 33 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 50120635 Common flgA flagellar basal body P-ring biosynthesis protein FlgA ECA1701 43 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 50121788 Common - hypothetical protein ECA2864 3 None None None 50121089 Common - putative luciferase-like monooxygenase ECA2161 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 50120845 Common - hypothetical protein ECA1915 48 COG3665 COG3665, Uncharacterized conserved protein Function unknown 50120807 Common nrfC nitrite reductase complex component ECA1877 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 50121774 Common mvpA putative plasmid protein ECA2850 59 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 50120060 Common yajC preprotein translocase subunit YajC ECA1121 165 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 50120606 Pathogen - hypothetical protein ECA1672A 1 None None None 50119541 Pathogen - hypothetical protein ECA0591 1 None None None 50123214 Pathogen - hypothetical protein ECA4294 2 None None None 50122722 Common hofC type IV pilin biogenesis protein ECA3800 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 50120456 Pathogen - hypothetical protein ECA1521 2 None None None 50121506 Common hisG ATP phosphoribosyltransferase ECA2582 201 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 50119817 Common - putative acetyltransferase ECA0875 85 COG0456 RimI, Acetyltransferases General function prediction only 50121108 Common - Bacteriophage polarity suppression protein ECA2181 5 None None None 50119718 Common prfB peptide chain release factor 2 ECA0773 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 50122658 Common - putative bacteriophage baseplate protein ECA3736 25 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 50121626 Common ehpB putative phenazine antibiotic biosynthesis protein ECA2702 80 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 50122532 Common rpsR 30S ribosomal protein S18 ECA3611 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 50122378 Pathogen - hypothetical protein ECA3455 1 None None None 50120020 Pathogen - hypothetical protein ECA1080 1 None None None 50123125 Common rffC TDP-fucosamine acetyltransferase ECA4205 15 COG0456 RimI, Acetyltransferases General function prediction only 50119054 Common fdhD formate dehydrogenase accessory protein ECA0093 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 50122500 Common - methyl-accepting chemotaxis protein ECA3579 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121340 Common nadE NAD synthetase ECA2412 163 COG0171 NadE, NAD synthase Coenzyme metabolism 50121026 Pathogen hrpF type III secretion protein ECA2098 1 None None None 50122702 Common - ArsR-family transcriptional regulator ECA3780 91 COG0640 ArsR, Predicted transcriptional regulators Transcription 50119466 Common - hypothetical protein ECA0515 100 COG3177 COG3177, Uncharacterized conserved protein Function unknown 50119909 Common - putative TetR-family transcriptional regulator ECA0969 11 COG1309 AcrR, Transcriptional regulator Transcription 50121078 Common - hypothetical protein ECA2150 22 COG2314 XynA, Predicted membrane protein Function unknown 50122270 Common - predicted lipoprotein ECA3348 126 COG4105 ComL, DNA uptake lipoprotein General function prediction only 50118975 Common rbsD high affinity ribose transport protein ECA0010 46 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 50122310 Pathogen - hypothetical protein ECA3386 1 None None None 50120868 Common gst glutathione S-transferase ECA1938 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50119575 Common ubiC chorismate pyruvate lyase ECA0626 45 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 50119330 Common - putative transcriptional regulator ECA0371 126 COG1733 COG1733, Predicted transcriptional regulators Transcription 50119073 Common - hypothetical protein ECA0112 68 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 50121765 Common - GntR-family transcriptional regulator ECA2841 125 COG2188 PhnF, Transcriptional regulators Transcription 50121014 Common hrpJ type III secretion protein ECA2086 6 None None None 50122612 Common - hypothetical protein ECA3691 111 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 50122562 Common aas bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase ECA3641 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50122009 Common - putative acetyltransferase ECA3086 17 COG0456 RimI, Acetyltransferases General function prediction only 50119778 Common - prophage integrase ECA0835 115 COG0582 XerC, Integrase DNA replication, recombination, and repair 50123332 Common - hypothetical protein ECA4414 10 None None None 50120114 Common apt adenine phosphoribosyltransferase ECA1175 189 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 50121230 Common - putative oligogalacturonate-specific porin ECA2302 12 None None None 50121709 Common prtW metalloprotease ECA2785 24 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 50123048 Common - ABC transporter, ATP-binding protein ECA4128 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 50123329 Common ssuD alkanesulfonate monooxygenase ECA4411 84 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 50122467 Common cysI sulfite reductase [NADPH] hemoprotein beta-component ECA3546 142 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 50120560 Common - hypothetical protein ECA1626 23 None None None 50122755 Common leuD isopropylmalate isomerase small subunit ECA3834 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 50123429 Common atpG F0F1 ATP synthase subunit gamma ECA4513 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 50119060 Common xylG D-xylose transport ATP-binding protein ECA0099 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 50121406 Common pykA pyruvate kinase ECA2481 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 50121570 Common lolA outer-membrane lipoprotein carrier protein ECA2646 75 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 50119858 Common - LysR-family transcriptional regulator ECA0916 185 COG0583 LysR, Transcriptional regulator Transcription 50120304 Common cydA1 cytochrome D ubiquinol oxidase subunit I ECA1365 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 50120533 Common ardC antirestriction protein ECA1600 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 50121252 Common oppA1 periplasmic oligopeptide-binding protein ECA2324 208 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 50123041 Common - citrate synthase ECA4121 193 COG0372 GltA, Citrate synthase Energy production and conversion 50119870 Common - TonB-like protein ECA0928 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 50122390 Common pepD aminoacyl-histidine dipeptidase ECA3467 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 50120024 Common - hypothetical protein ECA1084 41 None None None 50119548 Pathogen - hypothetical protein ECA0598 3 None None None 50123254 Common - methyl-accepting chemotaxis protein ECA4334 132 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120520 Common - probable short chain dehydrogenase ECA1586 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50121085 Common - ABC transporter, substrate binding protein ECA2157 93 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50122488 Common pyrG CTP synthetase ECA3567 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 50122481 Common - oligogalacturonide transporter ECA3560 53 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 50119572 Common fxsA suppressor of F plamsid exlusion of phage T7 ECA0623 65 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 50121644 Common - ABC transporter, permease protein ECA2720 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 50122975 Common - hypothetical protein ECA4055 18 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 50121531 Common - putative bacteriophage tail fiber assembly protein G ECA2607 13 None None None 50119579 Common lexA LexA repressor ECA0630 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 50120708 Common - putative iron-regulated membrane protein ECA1775 53 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 50121427 Pathogen - hypothetical protein ECA2502 1 None None None 50122267 Common clpB protein disaggregation chaperone ECA3345 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 50119703 Common - putative global regulator ECA0758 92 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 50121261 Common purU formyltetrahydrofolate deformylase ECA2333 219 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 50119820 Common - hypothetical protein ECA0878 15 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50120155 Pathogen katA putative catalase (partial) ECA1216 1 COG0753 KatE, Catalase Inorganic ion transport and metabolism 50122712 Common pdhR transcriptional regulator PdhR ECA3790 153 COG2186 FadR, Transcriptional regulators Transcription 50120992 Common - ABC transporter permease protein ECA2064 101 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 50119938 Common - putative mandelate racemase ECA0998 132 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50122013 Pathogen - hypothetical protein ECA3090 1 COG5189 SFP1, Putative transcriptional repressor regulating G2/M transition Transcription / Cell division and chromosome partitioning 50122396 Common gmhA phosphoheptose isomerase ECA3473 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 50122191 Common - HlyD family secretion protein ECA3269 146 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 50121597 Common - hypothetical protein ECA2673 9 None None None 50119635 Common - putative DNA-binding protein ECA0687 7 None None None 50120684 Common ompA outer membrane protein A ECA1751 147 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 50119127 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase ECA0167 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 50122852 Common hflK FtsH protease regulator HflK ECA3932 211 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 50120540 Pathogen - hypothetical protein ECA1607 1 None None None 50119383 Common - hypothetical protein ECA0432 44 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 50120747 Common - hypothetical protein ECA1816 26 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 50121878 Common nifK nitrogenase molybdenum-iron protein beta chain ECA2954 50 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 50122049 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase ECA3126 148 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 50122859 Common - hypothetical protein ECA3939 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 50120548 Common virB9 putative conjugal transfer protein ECA1615 44 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 50119423 Common - putative TatD-family deoxyribonuclease ECA0472 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 50122842 Common nucM endonuclease ECA3922 35 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 50119799 Common - ABC transporter, periplasmic binding protein ECA0856 145 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50120134 Common - hypothetical protein ECA1195 42 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 50121069 Common - amidase ECA2141 215 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 50122970 Common slyX hypothetical protein ECA4050 21 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 50119443 Common phnI putative phosphonate metabolism protein ECA0492 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 50119410 Common pepP proline aminopeptidase P II ECA0459 243 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 50121516 Common cmk cytidylate kinase ECA2592 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 50122057 Common - LysR-family transcriptional regulator ECA3134 133 COG0583 LysR, Transcriptional regulator Transcription 50122675 Common - hypothetical protein ECA3753 45 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 50121206 Common rnfC electron transport complex protein RnfC ECA2278 85 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 50122690 Common - putative formate acetyltransferase ECA3768 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 50121553 Common - conserved phage protein ECA2628 53 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 50120964 Common pecS regulatory protein ECA2036 64 COG1846 MarR, Transcriptional regulators Transcription 50123413 Common - hypothetical protein ECA4497 24 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 50121577 Common infA translation initiation factor IF-1 ECA2653 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 50120088 Common clpX ATP-dependent protease ATP-binding subunit ECA1149 232 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 50119846 Common fumA fumarate hydratase class I, aerobic ECA0904 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 50120189 Common fdhF formate dehydrogenase H ECA1250 194 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 50119974 Common frr ribosome recycling factor ECA1034 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 50119402 Common - hypothetical protein ECA0451 55 COG2862 COG2862, Predicted membrane protein Function unknown 50119491 Common pilU putative prepilin peptidase ECA0543 6 None None None 50120515 Common - hypothetical protein ECA1581 5 None None None 50121431 Pathogen - hypothetical protein ECA2506 1 None None None 50120251 Common gltK glutamate/aspartate transport system permease protein ECA1312 178 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50121871 Common nifX nitrogen fixation protein ECA2947 33 COG1433 COG1433, Uncharacterized conserved protein Function unknown 50122262 Common rnhA ribonuclease H ECA3340 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 50120985 Common - putative transport system, permease protein ECA2057 144 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 50122940 Common rplX 50S ribosomal protein L24 ECA4020 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 50121476 Common - hypothetical protein ECA2552 9 None None None 50119623 Pathogen - hypothetical protein ECA0675 1 None None None 50119720 Common - AraC-family transcriptional regulator ECA0775 129 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50120739 Common - probable transporter ECA1808 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122456 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ECA3535 194 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 50121294 Common - predicted isomerase/hydrolase ECA2366 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 50123150 Common - probable magnesium-chelatase ECA4230 189 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 50123424 Common glmS D-fructose-6-phosphate amidotransferase ECA4508 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 50120576 Pathogen - putative DNA-binding protein ECA1644 3 None None None 50121154 Common - chromosome replication initiation inhibitor protein ECA2227 124 COG0583 LysR, Transcriptional regulator Transcription 50121147 Common osmC osmotically inducible protein C ECA2221 100 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 50119142 Common - methyl-accepting chemotaxis protein ECA0182 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121740 Common moaB molybdenum cofactor biosynthesis protein B ECA2816 175 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 50119951 Common - putative Fe-S metabolism associated protein ECA1011 93 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 50120180 Common hyfG hydrogenase-4 component G ECA1241 195 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 50119112 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase ECA0151 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 50120643 Common flgI flagellar basal body P-ring protein ECA1709 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 50122721 Common hofB hypothetical protein ECA3799 222 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 50122444 Common - D,D-heptose 1,7-bisphosphate phosphatase ECA3523 133 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 50119434 Common - putative non-ribosomal peptide synthetase ECA0483 209 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50121300 Common fadD long-chain-fatty-acid--CoA ligase ECA2372 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50120496 Common - quorum-sensing transcriptional regulator ECA1561 54 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 50121268 Common ansA cytoplasmic asparaginase I ECA2340 136 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 50122936 Common rplF 50S ribosomal protein L6 ECA4016 231 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 50123081 Common - putative beta-hexosaminidase ECA4161 180 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 50119898 Common - putative acetyltransferase ECA0956 117 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 50121016 Common hrpX two-component sensor kinase ECA2088 165 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 50119958 Common xni exonuclease IX ECA1018 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 50123100 Common - predicted hydrolase ECA4180 73 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 50121473 Common mukF condesin subunit F ECA2549 19 COG3006 MukF, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 50119020 Common - transmembrane sensor ECA0058 44 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 50120822 Common napC cytochrome c-type protein NapC ECA1892 53 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 50121376 Common potA putrescine/spermidine ABC transporter ATPase protein ECA2450 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50119899 Common - hypothetical protein ECA0957 89 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 50122806 Common mogA molybdenum cofactor biosynthesis protein ECA3885 184 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 50120732 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II ECA1799 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50120511 Pathogen - putative lipoprotein ECA1577 1 None None None 50118990 Common glnG nitrogen regulation protein NR(I) ECA0027 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 50123107 Common cyaA adenylate cyclase ECA4187 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 50119514 Pathogen - hypothetical protein ECA0565 4 None None None 50119390 Common rhaA L-rhamnose isomerase ECA0439 23 COG4806 RhaA, L-rhamnose isomerase Carbohydrate transport and metabolism 50122150 Common - RpiR-family transcriptional regulator ECA3228 84 COG1737 RpiR, Transcriptional regulators Transcription 50121610 Common dacC penicillin-binding protein 6 ECA2686 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 50122170 Common - hypothetical protein ECA3248 32 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 50119507 Common - hypothetical protein ECA0558 4 COG1715 Mrr, Restriction endonuclease Defense mechanisms 50121857 Common - probable short-chain dehydrogenase ECA2933 226 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 50120671 Common - hypothetical protein ECA1738 15 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 50122895 Common ecnB entericidin B ECA3975 7 COG5510 COG5510, Predicted small secreted protein Function unknown 50118999 Common recG ATP-dependent DNA helicase RecG ECA0036 213 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 50121362 Common - hypothetical protein ECA2434 4 None None None 50120374 Pathogen rfc putative O-antigen polymerase ECA1435 2 None None None 50122737 Common murG N-acetylglucosaminyl transferase ECA3815 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 50119879 Common - putative transport protein ECA0937 91 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50120578 Pathogen - hypothetical protein ECA1646 2 None None None 50121249 Common oppD oligopeptide transporter ATP-binding component ECA2321 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 50123009 Common rpe ribulose-phosphate 3-epimerase ECA4089 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 50123233 Common - hypothetical protein ECA4313 6 None None None 50119619 Pathogen - putative bacteriophage derepression protein ECA0671 2 None None None 50119455 Common - putative capsular polysaccharide bisynthesis protein ECA0504 4 None None None 50122947 Common rpsS 30S ribosomal protein S19 ECA4027 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 50122816 Pathogen - hypothetical protein ECA3895 1 None None None 50119826 Common cysT sulfate/thiosulfate transporter subunit ECA0884 233 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 50121922 Common cydA2 cytochrome d ubiquinol oxidase subunit I ECA2998 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 50121971 Common hisM histidine ABC transporter permease protein ECA3048 173 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 50119254 Common - putative calcium/sodium:proton antiporter ECA0294 136 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 50122119 Common thiM hydroxyethylthiazole kinase ECA3197 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 50120770 Common gntT high-affinity gluconate transporter ECA1840 85 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 50120721 Common - hypothetical protein ECA1788 37 COG1359 COG1359, Uncharacterized conserved protein Function unknown 50120713 Common - putative NADH-dependent flavin oxidoreductase ECA1780 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 50119787 Common - putative tautomerase ECA0844 35 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 50122991 Common ppiA peptidyl-prolyl cis-trans isomerase A (rotamase A) ECA4071 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 50119259 Common - hypothetical protein ECA0299 19 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 50120206 Common - thioredoxin ECA1267 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 50121191 Common manA mannose-6-phosphate isomerase ECA2263 41 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 50121239 Pathogen - hypothetical protein ECA2311 3 None None None 50121619 Common - putative malonyl CoA-acyl carrier protein transacylase ECA2695 5 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 50122403 Common - hypothetical protein ECA3480 2 None None None 161501873 Common cydC cysteine/glutathione ABC transporter membrane/ATP-binding component ECA2651 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 50120782 Common - hypothetical protein ECA1852 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 50121592 Common artI arginine-binding periplasmic protein 1 ECA2668 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50120812 Common ccmA heme exporter protein A ECA1882 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 50121799 Common - putative ATP-binding protein ECA2875 10 None None None 50120204 Common - hypothetical protein ECA1265 28 COG2707 COG2707, Predicted membrane protein Function unknown 50119985 Common rnhB ribonuclease HII ECA1045 238 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 50120328 Common galE UDP-galactose-4-epimerase ECA1389 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 161501881 Common ddg lipid A biosynthesis palmitoleoyl acyltransferase ECA0781 92 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 50121710 Common dinG ATP-dependent DNA helicase DinG ECA2786 128 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 50119445 Common phnK phosphonates transport ATP-binding protein ECA0494 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 50120788 Pathogen - hypothetical protein ECA1858 2 None None None 50119355 Common - hypothetical protein ECA0398 2 None None None 50123279 Common - hypothetical protein ECA4359 57 COG1295 Rbn, Predicted membrane protein Function unknown 50121749 Common bioB biotin synthase ECA2825 180 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 50120187 Pathogen - hypothetical protein ECA1248 1 None None None 50119083 Pathogen - hypothetical protein ECA0122 1 None None None 50123083 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C ECA4163 184 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 50121984 Common - hypothetical protein ECA3061 74 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 50122534 Common rpsF 30S ribosomal protein S6 ECA3613 191 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 50119916 Common mutY adenine DNA glycosylase ECA0976 233 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 50120131 Common - hypothetical protein ECA1192 18 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 50119783 Common recN recombination and repair protein ECA0840 199 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 50120678 Common betB betaine aldehyde dehydrogenase ECA1745 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50122997 Common - putative mandelate racemase / muconate lactonizing enzyme ECA4077 111 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50120567 Pathogen - hypothetical protein ECA1635 2 None None None 50121283 Pathogen - hypothetical protein ECA2355 2 None None None 50121951 Common nuoA NADH dehydrogenase subunit A ECA3028 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 50121378 Common potC spermidine/putrescine ABC transporter membrane protein ECA2452 204 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 50119620 Common - putative phage-related protein ECA0672 10 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50122173 Common hmpX nitric oxide dioxygenase ECA3251 136 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 50122474 Common - putative 6-pyruvoyl tetrahydrobiopterin synthase ECA3553 123 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 50123186 Common glpF glycerol uptake facilitator protein ECA4266 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 50122156 Common hscB co-chaperone HscB ECA3234 57 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 50120007 Common - hypothetical protein ECA1067 6 None None None 50119337 Common - hypothetical protein ECA0378 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 50120182 Common hyfE hydrogenase 4 membrane subunit ECA1243 33 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 50119242 Common pmbA peptidase PmbA ECA0282 156 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 50123227 Common pfkA 6-phosphofructokinase ECA4307 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 50120140 Common gyrA DNA gyrase subunit A ECA1201 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 50121057 Pathogen - hypothetical protein ECA2129 3 None None None 50121528 Common - putative phage tail protein E' ECA2604 7 None None None 50119359 Common - hypothetical protein ECA0401 19 COG2323 COG2323, Predicted membrane protein Function unknown 50121037 Pathogen - putative lipoprotein ECA2109 3 None None None 50120294 Common nei endonuclease VIII ECA1355 174 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 50119509 Common - putative plasmid transfer protein ECA0560 33 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 50123318 Common - putative sodium:sulfate symporter ECA4400 75 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 50121368 Common - putative MutT family protein ECA2441 50 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 50122620 Common - conserved hypothetical phage-related protein ECA3699 3 None None None 50123000 Common nirD nitrite reductase small subunit ECA4080 46 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 50122738 Common ftsW cell division protein ECA3816 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 50122934 Common rpsE 30S ribosomal protein S5 ECA4014 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 50123223 Common - hypothetical protein ECA4303 8 None None None 50121316 Common - hypothetical protein ECA2388 16 COG4811 COG4811, Predicted membrane protein Function unknown 50120355 Common - undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase ECA1416 158 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 50119148 Common - PTS system, IIabc component ECA0188 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50119249 Common - putative ABC transporter ATP-binding protein YhbG ECA0289 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 50123063 Common - hypothetical protein ECA4143 2 None None None 50122526 Common ipdC indole-3-pyruvate decarboxylase ECA3605 221 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 50122064 Common - hypothetical protein ECA3141 13 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 50122967 Common - putative alanine racemase ECA4047 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 50122252 Common - ATP transporter ATP-binding protein ECA3330 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50123219 Common - putative biopolymer transport protein ECA4299 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 50121892 Common - ABC transporter permease protein ECA2968 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50119004 Pathogen - hypothetical protein ECA0041 1 None None None 50120637 Common flgC flagellar basal body rod protein FlgC ECA1703 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 50123189 Common fpr ferredoxin-NADP reductase ECA4269 129 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 50120488 Common - putative transposase (partial) ECA1553 9 COG5464 COG5464, Uncharacterized conserved protein Function unknown 50122416 Common - putative amino acid ABC transporter, substrate binding protein ECA3495 162 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50122070 Common ugd UDP-glucose 6-dehydrogenase ECA3147 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 50121911 Common - hypothetical protein ECA2987 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 50123132 Common - thioredoxin ECA4212 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 50120175 Common hyfR hydrogenase-4 transcriptional activator ECA1236 172 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 50122986 Common - para-aminobenzoate synthase component II ECA4066 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 50122096 Common malK maltose/maltodextrin transport ATP-binding protein ECA3174 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 50122215 Common - putative oxidoreductase ECA3293 188 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 50123096 Common abrB hypothetical protein ECA4176 56 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 50123346 Common - predicted hydrolase ECA4428 139 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 50122052 Common dltB peptidoglycan biosynthesis protein ECA3129 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 50122836 Common - putative peptidase ECA3915 101 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 50121600 Common potG putrescine transporter ATP-binding subunit ECA2676 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 50122774 Common hepA ATP-dependent helicase HepA ECA3853 138 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 50122629 Pathogen - putative phage-related DNA-binding protein ECA3708 2 COG1395 COG1395, Predicted transcriptional regulator Transcription 50120789 Common sufA iron-sulfur cluster assembly scaffold protein ECA1859 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 50120863 Common anmK anhydro-N-acetylmuramic acid kinase ECA1933 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 50122068 Common - undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase ECA3145 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 50121759 Common - putative ABC transporter ATP-binding protein ECA2835 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 50122549 Common proC pyrroline-5-carboxylate reductase ECA3628 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 50122983 Common - hypothetical protein ECA4063 87 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 50120367 Common nahO acetaldehyde dehydrogenase ECA1428 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 50119675 Common deoD purine nucleoside phosphorylase ECA0730 99 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 50119140 Common metR transcriptional activator protein ECA0180 175 COG0583 LysR, Transcriptional regulator Transcription 50119036 Common - ABC transporter permease protein ECA0074 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121828 Common - putative lipoprotein ECA2904 5 None None None 50119283 Common - putative tetrapyrrole methylase ECA0323 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 50121609 Common deoR DNA-binding transcriptional repressor ECA2685 114 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 50121889 Common - putative mandelate racemase / muconate lactonizing enzyme ECA2965 114 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50123304 Common avtA valine--pyruvate transaminase ECA4386 154 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 50120285 Common - ABC transporter substrate binding protein ECA1346 115 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 50121525 Common - major tail sheath protein FI ECA2601 36 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 50123384 Common - binding-protein-dependent transport system inner membrane component ECA4467 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50120401 Common - probable oxidoreductase ECA1462 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50120508 Common - probable transporter ECA1574 232 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120886 Common - translation initiation factor Sui1 ECA1958 49 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 50121000 Common - flavodoxin ECA2072 84 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 50119561 Common - hypothetical protein ECA0611 35 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 50119988 Common - hypothetical protein ECA1048 44 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 50122920 Common fmt methionyl-tRNA formyltransferase ECA4000 219 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 50123110 Common hemX putative uroporphyrinogen III C-methyltransferase ECA4190 55 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 50123061 Common glpD glycerol-3-phosphate dehydrogenase ECA4141 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 50121009 Pathogen hrpP type III secretion protein ECA2081 1 None None None 50119233 Common tldD putative modulator of DNA gyrase ECA0273 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 50119851 Common alkB alkylated DNA repair protein ECA0909 58 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 50123178 Common priA primosome assembly protein PriA ECA4258 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 50121832 Common - putative plasmid replication protein ECA2908 3 None None None 50123180 Common ftsN cell division protein FtsN ECA4260 44 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 50121916 Common nasD nitrate transport protein ECA2992 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50120558 Common - hypothetical plasmid protein ECA1624 7 None None None 50119094 Common - hypothetical protein ECA0133 35 COG2362 DppA, D-aminopeptidase Amino acid transport and metabolism 50122887 Common bspA predicted mechanosensitive channel ECA3967 178 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 50122022 Common outN general secretion pathway protein N ECA3099 10 None None None 50123404 Common - putative allophanate hydrolase subunit 1 ECA4488 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 50122454 Common truD tRNA pseudouridine synthase D ECA3533 86 COG0585 COG0585, Uncharacterized conserved protein Function unknown 50122239 Common dksA DnaK transcriptional regulator DksA ECA3317 141 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 50122442 Common - hypothetical protein ECA3521 13 COG5544 COG5544, Predicted periplasmic lipoprotein General function prediction only 50122425 Common proX glycine betaine transporter periplasmic subunit ECA3504 61 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 50123117 Common - probable lyase ECA4197 237 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 50121637 Common - LysR-family transcriptional regulator ECA2713 156 COG0583 LysR, Transcriptional regulator Transcription 50122272 Common pheA bifunctional chorismate mutase/prephenate dehydratase ECA3350 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 50119387 Common - methyl-accepting chemotaxis protein ECA0436 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120858 Common rnt ribonuclease T ECA1928 61 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 50123171 Common metL bifunctional aspartate kinase II/homoserine dehydrogenase II ECA4251 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 50119716 Common dsbC thiol:disulfide interchange protein DsbC ECA0771 66 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 50120059 Common tgt queuine tRNA-ribosyltransferase ECA1120 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 50121670 Common - hypothetical protein ECA2746 32 COG3503 COG3503, Predicted membrane protein Function unknown 50122244 Common panC pantoate--beta-alanine ligase ECA3322 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 50121093 Common ascF cellobiose/arbutin/salicin-specific PTS system components IIBC ECA2165 46 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50121630 Common - hypothetical protein ECA2706 3 COG5587 COG5587, Uncharacterized conserved protein Function unknown 50122960 Common dsrF hypothetical protein ECA4040 36 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 50119940 Common amiC N-acetylmuramoyl-L-alanine amidase ECA1000 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 50119273 Common - hypothetical protein ECA0313 90 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 50120346 Common fdnH formate dehydrogenase, nitrate-inducible, iron-sulfur subunit ECA1407 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 50121855 Common - TetR-family transcriptional regulator ECA2931 53 COG1309 AcrR, Transcriptional regulator Transcription 50121739 Common moaC molybdenum cofactor biosynthesis protein C ECA2815 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 50119593 Common exuT galacturonate transporter ECA0644 199 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50120261 Common - hypothetical protein ECA1322 2 None None None 50119081 Common - hypothetical protein ECA0120 191 COG0628 PerM, Predicted permease General function prediction only 50120976 Common - hypothetical protein ECA2048 41 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 50121200 Common araG L-arabinose transporter ATP-binding protein ECA2272 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 50119121 Common waaQ lipopolysaccharide core biosynthesis protein ECA0160 106 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 50121136 Common - periplasmic binding protein precursor ECA2210 72 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50119539 Pathogen - hypothetical protein ECA0589 1 None None None 50119734 Common - hypothetical protein ECA0789 132 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 50121721 Common mmuM homocysteine methyltransferase ECA2797 134 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 50122496 Common gudD glucarate dehydratase ECA3575 49 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50120853 Common - riboflavin synthase subunit alpha ECA1923 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 50122637 Common - putative phage-related exported protein ECA3716 9 None None None 50120905 Common sapA peptide transport periplasmic protein ECA1977 211 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 50120404 Common - hypothetical protein ECA1465 52 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 50119395 Common - antitoxin YefM ECA0444 52 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 50120661 Common fliT flagellar biosynthesis protein FliT ECA1728 12 None None None 50122575 Common - LysR-family transcriptional regulator ECA3654 151 COG0583 LysR, Transcriptional regulator Transcription 50121134 Common ogt methylated-DNA--protein-cysteine methyltransferase ECA2208 203 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 50121728 Common - hypothetical protein ECA2804 24 COG5642 COG5642, Uncharacterized conserved protein Function unknown 50123070 Common glgX glycogen debranching enzyme ECA4150 158 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 50122360 Common - hypothetical protein ECA3437 45 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 50123397 Common - probable short-chain dehydrogenase ECA4481 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 50120178 Common hyfI hydrogenase-4 component I ECA1239 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 50121384 Common - putative AraC-family transcriptional regulator ECA2458 35 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50122548 Common - putative alanine racemase ECA3627 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 50119537 Common - hypothetical protein ECA0587 17 None None None 50120751 Common - putative chaperone ECA1820 190 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 50122882 Pathogen - hypothetical protein ECA3962 3 None None None 50120528 Common - hypothetical protein ECA1594 5 None None None 50120695 Common - hypothetical protein ECA1762 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 50121803 Common - integrase ECA2879 102 COG0582 XerC, Integrase DNA replication, recombination, and repair 50120827 Common napD assembly protein for periplasmic nitrate reductase ECA1897 12 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 50123433 Common atpE F0F1 ATP synthase subunit C ECA4517 50 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 50119568 Common dipZ thiol:disulfide interchange protein precursor ECA0618 154 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 50121211 Common tppB putative tripeptide transporter permease ECA2283 84 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 50122388 Common frsA fermentation/respiration switch protein ECA3465 19 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 50123353 Common - pts system, IIb component ECA4435 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 50119236 Common tdrA putative DNA-binding transcriptional regulator ECA0276 182 COG0583 LysR, Transcriptional regulator Transcription 50119275 Pathogen - putative lipoprotein ECA0315 1 None None None 50123285 Pathogen - hypothetical protein ECA4365 2 None None None 50122121 Common - hypothetical protein ECA3199 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50119305 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase ECA0346 147 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 50119521 Common - putative lipoprotein ECA0572 21 None None None 50120616 Common dsrB hypothetical protein ECA1682 10 None None None 50122299 Common - glutaredoxin 2 ECA3377 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 50122517 Common - hypothetical protein ECA3596 125 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 50122524 Common - putative flavodoxin ECA3603 78 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 50121465 Common asnC asparaginyl-tRNA synthetase ECA2541 226 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 50122086 Common ppk polyphosphate kinase ECA3164 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 50120874 Common pgpB phosphatidylglycerophosphatase B ECA1944 22 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 50121304 Common - putative endoribonuclease ECA2376 66 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 50123247 Common - putative oxidoreductase ECA4327 154 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 50121808 Pathogen - hypothetical protein ECA2884 1 None None None 50119485 Pathogen pilP putative Type IV pilus protein ECA0537 1 None None None 50122226 Common btuF vitamin B12-transporter protein BtuF ECA3304 148 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50121489 Common sbcB exonuclease I ECA2565 52 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 50120435 Common uhpA two-component system response regulator protein ECA1497 198 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50122092 Common galK galactokinase ECA3170 84 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 50119963 Common - MarR-family transcriptional regulator ECA1023 9 COG1846 MarR, Transcriptional regulators Transcription 50120640 Common flgF flagellar basal body rod protein FlgF ECA1706 121 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 50120095 Common - putative pyridoxal-phosphate dependent protein ECA1156 210 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 50119372 Common - putative exported lipase ECA0421 22 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 50121396 Common - hypothetical protein ECA2470 18 None None None 50120977 Common - hypothetical protein ECA2049 14 None None None 50123011 Common damX hypothetical protein ECA4091 25 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 50120445 Common - putative iron permease ECA1510 87 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 50121045 Common hecA1 hemolysin/hemagglutinin-like protein ECA2117 103 None None None 50121209 Common rnfE SoxR-reducing system protein RsxE ECA2281 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 50122188 Common - putative hemagglutinin/hemolysin-related protein ECA3266 177 None None None 50119965 Common - tRNA pseudouridine synthase C ECA1025 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 50119480 Common - hypothetical protein ECA0528 21 None None None 50122600 Common - hypothetical protein ECA3679 46 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 50122369 Common oprJ multidrug resistance outer membrane protein ECA3446 129 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50122269 Common rluD 23S rRNA pseudouridine synthase D ECA3347 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 50122290 Common recX recombination regulator RecX ECA3368 39 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 50119763 Common - O-acetyl-L-homoserine sulfhydrylase ECA0820 207 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 50123341 Common - putative nucleoside hydrolase ECA4423 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 50122664 Common - putative bacteriophage tail fiber assembly protein ECA3742 8 None None None 50119949 Common - biotin sulfoxide reductase ECA1009 150 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 50121901 Common - hypothetical protein ECA2977 7 None None None 50120958 Common narK nitrite extrusion protein ECA2030 74 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 50119633 Common mdh malate dehydrogenase ECA0685 174 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 50121309 Common - LysR-family transcriptional regulator ECA2381 184 COG0583 LysR, Transcriptional regulator Transcription 50122610 Common uvrA excinuclease ABC subunit A ECA3689 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 50120777 Common aglB 6-phospho-alpha-glucosidase ECA1847 52 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 50119476 Common - hypothetical protein ECA0524 22 None None None 50120276 Common - hypothetical protein ECA1337 48 COG2510 COG2510, Predicted membrane protein Function unknown 50122124 Common - LysR-family transcriptional regulator ECA3202 191 COG0583 LysR, Transcriptional regulator Transcription 50120219 Common - esterase YpfH ECA1280 40 COG0400 COG0400, Predicted esterase General function prediction only 50120469 Common hasF outer membrane secretion protein ECA1534 132 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50122260 Common nrdF ribonucleotide-diphosphate reductase subunit beta ECA3338 146 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 50122826 Common serA D-3-phosphoglycerate dehydrogenase ECA3905 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 50119000 Common trmH tRNA guanosine-2'-O-methyltransferase ECA0037 201 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 50123280 Common kdgK 2-dehydro-3-deoxygluconokinase ECA4360 126 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 50122394 Common - hypothetical protein ECA3471 52 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 50121067 Pathogen - hypothetical protein ECA2139 1 None None None 50120382 Common galF UTP--glucose-1-phosphate uridylyltransferase ECA1443 214 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 50121182 Pathogen - putative lipoprotein ECA2254 2 None None None 50120584 Common - transposase ECA1652 117 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 50122146 Common ndk nucleoside diphosphate kinase ECA3224 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 50120087 Common clpP ATP-dependent Clp protease proteolytic subunit ECA1148 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 50120485 Common - putative transport system membrane protein ECA1550 176 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 50119994 Common - putative integrase ECA1054 25 None None None 50122652 Pathogen - hypothetical protein ECA3731 1 None None None 50120730 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase ECA1797 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50119950 Common - hypothetical protein ECA1010 220 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 50119222 Common aroQ 3-dehydroquinate dehydratase ECA0262 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 50120084 Common - hypothetical protein ECA1145 17 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 50120030 Common - putative lipoprotein ECA1090 58 COG1647 COG1647, Esterase/lipase General function prediction only 50121059 Pathogen - hypothetical protein ECA2131 2 None None None 50120158 Common - competence damage-inducible protein A ECA1219 143 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 50120490 Common - hypothetical protein ECA1555 14 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 50121478 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase ECA2554 143 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 50122567 Common celH putative 6-phospho-beta-glucosidase ECA3646 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 50121819 Pathogen - hypothetical protein ECA2895 1 None None None 50119366 Common - putative plasmid-related protein ECA0408 13 COG3905 COG3905, Predicted transcriptional regulator Transcription 50122685 Common - putative dihydrodipicolinate synthase ECA3763 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 50122898 Common - putative lipoprotein ECA3978 15 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 50122671 Common - plant-inducible protein ECA3749 20 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 50120359 Common rfbP undecaprenyl-phosphate galactosephosphotransferase ECA1420 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 50119320 Common scrB sucrose-6-phosphate hydrolase ECA0361 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 50121786 Common - hypothetical protein ECA2862 8 None None None 50120379 Common rfbD dTDP-4-dehydrorhamnose reductase ECA1440 185 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 50121421 Common aspS aspartyl-tRNA synthetase ECA2496 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50123415 Common - putative glycosyl transferase ECA4499 78 COG4261 COG4261, Predicted acyltransferase General function prediction only 50121117 Common prfA peptide chain release factor 1 ECA2190 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 50119230 Common maf Maf-like protein ECA0270 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 50119891 Common - hypothetical protein ECA0949 89 COG0730 COG0730, Predicted permeases General function prediction only 50120437 Common pnl pectin lyase ECA1499 16 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 50120350 Common udk uridine kinase ECA1411 83 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 50121504 Common - putative methyl-accepting chemotaxis citrate transducer ECA2580 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50121047 Common - hypothetical protein ECA2119 2 None None None 50119743 Common - hypothetical protein ECA0798 10 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 50122371 Common mexC multidrug resistance protein ECA3448 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 50121815 Common - hypothetical protein ECA2891 18 COG4271 COG4271, Predicted nucleotide-binding protein containing TIR -like domain Transcription 50119813 Common maeB malic enzyme ECA0871 217 COG0281 SfcA, Malic enzyme Energy production and conversion 50123020 Common nudE ADP-ribose diphosphatase NudE ECA4100 134 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 50121303 Common - putative ATP-dependent helicase ECA2375 141 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 50122321 Pathogen - hypothetical protein ECA3397 1 None None None 50118985 Common dsbA periplasmic protein disulfide isomerase I ECA0020 65 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 50121293 Common - hypothetical protein ECA2365 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 50119904 Common - putative regulatory protein ECA0964 23 None None None 50121360 Common - two-component sensor kinase ECA2432 106 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 50121776 Common - hypothetical protein ECA2852 13 None None None 50123080 Common gntR gluconate utilization system Gnt-I transcriptional repressor (partial) ECA4160 122 COG1609 PurR, Transcriptional regulators Transcription 50122763 Common - putative isoflavone oxidoreductase ECA3842 8 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 50119877 Common fhuE ferric-rhodotorulic acid outer membrane transporter ECA0935 110 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 50123257 Common livF leucine/isoleucine/valine transporter ATP-binding subunit ECA4337 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 50119464 Common - putative phage transcriptional regulator ECA0513 24 COG3423 Nlp, Predicted transcriptional regulator Transcription 50120400 Common - putative sugar ABC transporter, permease protein ECA1461 143 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 50122619 Common - hypothetical protein ECA3698 3 None None None 50121588 Common - hypothetical protein ECA2664 109 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50119169 Common pepQ proline dipeptidase ECA0209 113 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 50119957 Common - hypothetical protein ECA1017 46 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 50121243 Common tonB transport protein TonB ECA2315 30 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 50119199 Common - putative lipoprotein ECA0239 10 None None None 50123106 Common - hypothetical protein ECA4186 49 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 50120876 Common - putative sugar ABC transporter, ATP-binding protein ECA1948 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 50119819 Common - TonB-like protein ECA0877 16 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 50121018 Common hrpS sigma-54-dependent enhancer-binding protein ECA2090 164 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 50122591 Common tyrB aromatic amino acid aminotransferase ECA3670 85 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 50119800 Common - putative beta-glucoside operon antiterminator ECA0858 29 COG3711 BglG, Transcriptional antiterminator Transcription 50121367 Common - putative RNA pseudouridylate synthase ECA2440 202 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 50119345 Common - putative acetyltransferase ECA0386 70 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 50120608 Common - hypothetical protein ECA1674 7 None None None 50119545 Pathogen - hypothetical protein ECA0595 3 None None None 50119939 Common argA N-acetylglutamate synthase ECA0999 202 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 50120327 Common galM aldose 1-epimerase ECA1388 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 50120240 Common rlpA rare lipoprotein A ECA1301 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 50122142 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase ECA3220 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 50120112 Common priC primosomal replication protein N'' ECA1173 22 COG3923 PriC, Primosomal replication protein N'' DNA replication, recombination, and repair 50119075 Common - hypothetical protein ECA0114 79 COG3000 ERG3, Sterol desaturase Lipid metabolism 50119353 Common - putative haemolysin-like protein ECA0396 10 COG1475 Spo0J, Predicted transcriptional regulators Transcription 50119347 Common - putative peptidase ECA0388 98 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 50120535 Common - LysR-family transcriptional regulator ECA1602 111 COG0583 LysR, Transcriptional regulator Transcription 50122560 Common - putative acyltransferase ECA3639 84 COG2153 ElaA, Predicted acyltransferase General function prediction only 50120974 Common - putative bifunctional enzyme including aminotransferase and chitin synthase ECA2046 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 50121595 Common artJ arginine-binding periplasmic protein 2 ECA2671 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50120181 Common hyfF hydrogenase 4 subunit F ECA1242 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 50122794 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase ECA3873 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 50123237 Common - putative transporter ECA4317 144 COG0679 COG0679, Predicted permeases General function prediction only 50122459 Common - amino acid ABC transporter ECA3538 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50121177 Common - hypothetical protein ECA2249 36 None None None 50120016 Common fecB iron-dicitrate transporter substrate-binding subunit ECA1076 85 COG4594 FecB, ABC-type Fe3+-citrate transport system, periplasmic component Inorganic ion transport and metabolism 50122830 Common - arginine exporter protein ECA3909 83 COG1279 COG1279, Lysine efflux permease General function prediction only 50119278 Common - hypothetical protein ECA0318 8 None None None 50123334 Common dgoA1 DgoA protein [includes: 2-dehydro-3-deoxyphosphogalactonate aldolase; galactonate dehydratase] ECA4416 119 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50121282 Common ulaA ascorbate-specific PTS system enzyme IIC ECA2354 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 50123327 Common - PTS system, cellobiose-specific IIb component ECA4409 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 50119362 Common pepA leucyl aminopeptidase ECA0404 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 50119205 Common aapJ general L-amino ABC transporter binding protein ECA0245 120 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50119604 Common fadF putative 2,4-dienoyl-coA reductase ECA0655 192 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 50121333 Common togA ABC transporter, ATP-binding component ECA2405 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 50119382 Common - hypothetical protein ECA0431 4 None None None 50119930 Common ppdB hypothetical protein ECA0990 12 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 50120749 Common - putative transporter ECA1818 29 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119405 Pathogen - hypothetical protein ECA0454 1 None None None 50120542 Common - mobilization protein ECA1609 7 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 50122730 Common - hypothetical protein ECA3808 15 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 50122857 Common amiB N-acetylmuramoyl-L-alanine amidase ECA3937 181 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 50122506 Common glnE bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase ECA3585 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 50122483 Common calB coniferyl aldehyde dehydrogenase ECA3562 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50123234 Common - hypothetical protein ECA4314 9 None None None 50119288 Common - hypothetical protein ECA0329 15 COG5463 COG5463, Predicted integral membrane protein Function unknown 50119570 Common dcuA anaerobic C4-dicarboxylate transporter ECA0620 37 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 50121429 Common - resolvase ECA2504 93 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 50123306 Common - PTS system, IIabc component ECA4388 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50120302 Common sucC succinyl-CoA synthetase subunit beta ECA1363 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 50123016 Pathogen - hypothetical protein ECA4096 1 None None None 50121679 Pathogen - hypothetical protein ECA2755 1 None None None 50122125 Common - hypothetical protein ECA3203 17 None None None 50120457 Pathogen - hypothetical protein ECA1522 1 None None None 50121433 Common - conserved hypothetical protein (partial) ECA2509 26 COG1801 COG1801, Uncharacterized conserved protein Function unknown 50122834 Common epd D-erythrose 4-phosphate dehydrogenase ECA3913 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 50119066 Common expI N-acylhomoserine lactone synthesis protein ECA0105 21 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 50119190 Common thiS sulfur carrier protein ThiS ECA0229A 20 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 50119425 Common entD enterobactin synthetase component D (4'-phosphopantetheinyl transferase) ECA0474 36 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 50123410 Common - 3-oxoacyl-(acyl carrier protein) synthase I ECA4494 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50119998 Pathogen - hypothetical protein ECA1058 2 None None None 50119797 Common - ABC transporter, ATP-binding protein ECA0854 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50122199 Common era GTP-binding protein Era ECA3277 231 COG1159 Era, GTPase General function prediction only 50121051 Pathogen - hypothetical protein ECA2123 1 None None None 50119086 Common - hypothetical protein ECA0125 2 None None None 50122645 Common - conserved phage-related protein ECA3724 11 None None None 50121672 Common - hypothetical protein ECA2748 21 COG3082 COG3082, Uncharacterized protein conserved in bacteria Function unknown 50121511 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase ECA2587 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 50120623 Common cheA chemotaxis protein CheA ECA1689 152 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 50119437 Pathogen - hypothetical protein ECA0486 1 None None None 50122917 Common smg hypothetical protein ECA3997 40 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 50122714 Common - hypothetical protein ECA3792 84 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 50120686 Common - hypothetical protein ECA1753 19 COG3070 TfoX, Regulator of competence-specific genes Transcription 50120701 Common - putative acetyltransferase ECA1768 18 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 50121667 Common - hypothetical protein ECA2743 13 None None None 50122468 Common cysJ sulfite reductase subunit alpha ECA3547 101 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 50120742 Common - putative lipoprotein ECA1811 16 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 50121530 Common - putative bacteriophage tail fiber protein U ECA2606 26 COG3499 COG3499, Phage protein U General function prediction only 50120450 Common - ABC transporter ATP binding protein ECA1515 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 50119936 Common RecD exonuclease V subunit alpha ECA0996 137 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 50122713 Common aroP aromatic amino acid transport protein ECA3791 182 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 50120483 Common - putative transport system membrane protein ECA1548 139 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121555 Common - hypothetical protein ECA2630 9 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 50123367 Common - hypothetical protein ECA4449 101 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50120009 Common - hypothetical protein ECA1069 20 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 50121073 Common - putative branched-chain amino acid transport system, permease component ECA2145 87 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 50121722 Common mmuP S-methylmethionine transporter ECA2798 191 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 50119048 Common mtlA PTS system, mannitol-specific IIabc component ECA0087 76 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 50120523 Common lhr putative ATP-dependent helicase Lhr ECA1589 144 COG1201 Lhr, Lhr-like helicases General function prediction only 50120842 Common - putative ABC transporter, periplasmic protein ECA1912 74 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 50121902 Common - hypothetical protein ECA2978 5 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 50119863 Common - GntR-family transcriptional regulator ECA0921 137 COG1802 GntR, Transcriptional regulators Transcription 50119729 Common - putative sodium/hydrogen antiporter ECA0784 107 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 50122913 Common - putative transferase ECA3993 190 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 50121968 Common folX D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase ECA3045 45 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 50121695 Common - putative peptidase ECA2771 33 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 50120575 Pathogen - hypothetical protein ECA1643 1 None None None 50121327 Common kdgF pectin degradation protein ECA2399 34 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 50120277 Common kdpE DNA-binding response regulator in two-component regulatory system with KdpD ECA1338 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50122133 Common prt1 extracellular metalloprotease ECA3211 46 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 50119059 Common xylF D-xylose transporter subunit XylF ECA0098 97 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 50119117 Common - hypothetical protein ECA0156 3 None None None 50119228 Common mreC cell wall structural complex MreBCD transmembrane component MreC ECA0268 132 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 50122605 Common - hypothetical protein ECA3684 21 None None None 50122429 Common - putative transport protein ECA3508 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50123193 Common - hypothetical protein ECA4273 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 50119722 Common - hypothetical protein ECA0777 66 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 50121405 Common hexR DNA-binding transcriptional regulator HexR ECA2480 100 COG1737 RpiR, Transcriptional regulators Transcription 50119653 Common - putative degenerate non-ribosomal peptide synthetase (partial) ECA0706 14 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50121255 Common tdk thymidine kinase ECA2327 95 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 50122389 Common gpt xanthine-guanine phosphoribosyltransferase ECA3466 66 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 50121106 Pathogen - hypothetical protein ECA2179 1 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 50119367 Common - putative plasmid-related protein ECA0409 9 COG3668 ParE, Plasmid stabilization system protein General function prediction only 50119179 Common rplK 50S ribosomal protein L11 ECA0219 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 50122479 Common - short chain dehydrogenase ECA3558 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50122728 Common secA preprotein translocase subunit SecA ECA3806 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 50123286 Common - hypothetical protein ECA4366 16 None None None 50123348 Pathogen - putative lipoprotein ECA4430 3 None None None 50122439 Common - hypothetical protein ECA3518 37 COG3148 COG3148, Uncharacterized conserved protein Function unknown 50120424 Common - ABC transporter ATP-binding protein ECA1486 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 50122339 Common xerC site-specific tyrosine recombinase XerC ECA3415 221 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50119022 Common - hypothetical protein ECA0060 8 None None None 50122513 Common - methyl-accepting chemotaxis protein ECA3592 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120105 Common - hypothetical protein ECA1166 10 None None None 50120834 Common - probable zinc-binding dehydrogenase ECA1904 179 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 50122372 Common nfxB transcriptional regulator of multidrug resistance genes ECA3449 12 None None None 50119100 Common - putative mandelate racemase / muconate lactonizing enzyme family protein ECA0139 93 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 50122638 Common - conserved hypothetical phage-related protein ECA3717 10 None None None 50121038 Common - hypothetical protein ECA2110 36 COG4104 COG4104, Uncharacterized conserved protein Function unknown 50123131 Common rho transcription termination factor Rho ECA4211 202 COG1158 Rho, Transcription termination factor Transcription 50121024 Pathogen hrpD type III secretion protein ECA2096 2 None None None 50120283 Common - hypothetical protein ECA1344 11 None None None 50119170 Common - hypothetical protein ECA0210 131 COG1739 COG1739, Uncharacterized conserved protein Function unknown 50120230 Common dapE succinyl-diaminopimelate desuccinylase ECA1291 213 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 50122203 Common rseC SoxR reducing system protein RseC ECA3281 17 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 50121373 Common pehS sensor protein PhoQ ECA2446 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50122234 Common fhuC iron-hydroxamate transporter ATP-binding subunit ECA3312 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 50120228 Common - hypothetical protein ECA1289 10 None None None 50121173 Common - 4-oxalocrotonate tautomerase ECA2245 14 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 50122380 Common - hypothetical protein ECA3457 6 None None None 50120659 Common fliF flagellar MS-ring protein ECA1726 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 50121716 Common pbpG D-alanyl-D-alanine endopeptidase ECA2792 148 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 50119543 Common - putative DNA repair protein ECA0593 175 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 50122053 Pathogen dltD poly(glycerophosphate chain) D-alanine transfer protein ECA3130 3 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 50120673 Common fliZ protein FliZ ECA1740 9 None None None 50122753 Common leuB 3-isopropylmalate dehydrogenase ECA3832 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 50119011 Common uspB universal stress protein UspB ECA0049 12 None None None 50121348 Common rpmI 50S ribosomal protein L35 ECA2420 138 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 50119161 Common tatC TatABCE protein translocation system subunit ECA0201 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 50121317 Common - hypothetical protein ECA2389 65 COG1971 COG1971, Predicted membrane protein Function unknown 50119738 Common - putative type IV pilus protein ECA0793 79 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 50120959 Common narG respiratory nitrate reductase 1 alpha chain ECA2031 110 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 50122535 Common - predicted hydrolase ECA3614 34 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 50122788 Common - putative LysE-type translocator ECA3867 121 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50122956 Common fusA elongation factor G ECA4036 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 50121140 Common - putative amine oxidoreductase ECA2214 69 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 50121932 Common - coproporphyrinogen III oxidase ECA3009 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 50119856 Common - putative component of polysulfide reductase ECA0914 159 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 50121351 Common - aromatic amino acid transport protein ECA2423 160 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 50119202 Common aapP L-amino acid ABC transporter ATP-binding protein ECA0242 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50123284 Common - hypothetical protein ECA4364 18 None None None 50122646 Common - putative phage-related exported protein ECA3725 5 None None None 50120597 Common hns1 DNA-binding protein Hns ECA1665 27 COG2916 Hns, DNA-binding protein H-NS General function prediction only 50121646 Common - exogenous ferric siderophore TonB-dependent receptor ECA2722 129 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 50122309 Common - hypothetical protein ECA3385 18 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 50122502 Pathogen - hypothetical protein ECA3581 1 None None None 50119473 Common - hypothetical protein ECA0522 24 None None None 50123375 Common - putative lipoprotein ECA4458 23 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 50120035 Common - putative type I secretion protein ECA1096 139 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 50120477 Common - putative aldehyde dehydrogenase ECA1542 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50119154 Common argH argininosuccinate lyase ECA0194 233 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 50123164 Common metF 5,10-methylenetetrahydrofolate reductase ECA4244 154 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 50122446 Common metI DL-methionine transporter permease subunit ECA3525 155 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 50119696 Common - probable sugar ABC transporter, ATP-binding protein ECA0751 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 50119237 Common - hypothetical protein ECA0277 10 None None None 50119317 Common exbB biopolymer transport protein ECA0358 146 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 50120015 Common fecC iron-dicitrate transporter permease subunit ECA1075 187 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50120196 Common - DNA replication initiation factor ECA1257 170 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 50120950 Pathogen - putative surface antigen protein ECA2022A 1 None None None 50119229 Common mreD rod shape-determining protein MreD ECA0269 61 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 50119730 Common - two component system response regulator ECA0785 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50122839 Pathogen - hypothetical protein ECA3919 1 None None None 50120724 Common maf Maf-like protein ECA1791 193 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 161501874 Common trpD anthranilate phosphoribosyltransferase ECA2298 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 50121277 Common - hypothetical protein ECA2349 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 50123207 Pathogen - hypothetical protein ECA4287 2 None None None 50121031 Pathogen hrpN harpin ECA2103 1 COG5403 COG5403, Uncharacterized conserved protein Function unknown 50123053 Common - gluconate periplasmic binding protein ECA4133 156 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 50119771 Common - putative amino acid-binding periplasmic protein ECA0828 160 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50121974 Common ubiX 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ECA3051 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 50122165 Common - putative ferric-enterobactin ABC transporter ATP-binding protein ECA3243 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 50119914 Common mltC murein transglycosylase C ECA0974 122 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 50121263 Common xthA exonuclease III ECA2335 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 50119213 Common doc putative death on curing protein ECA0253 3 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 50123203 Common xerC site-specific tyrosine recombinase XerC ECA4283 222 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50119296 Common mdaB putative modulator of drug activity B ECA0337 46 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 50121494 Common citX apo-citrate lyase phosphoribosyl-dephospho-CoA transferase ECA2570 24 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 50119251 Common - hypothetical protein ECA0291 26 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 50120044 Common - putative methyl-accepting chemotaxis protein ECA1105 134 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50123111 Common hemY putative protoheme IX biogenesis protein ECA4191 48 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 50119018 Common - putative TonB-dependent heme receptor ECA0056 85 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 50122504 Common ligA NAD-dependent DNA ligase LigA ECA3583 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 50120108 Common acrB acriflavin resistance protein B ECA1169 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 50120093 Common - putative thioesterase ECA1154 15 COG0824 FcbC, Predicted thioesterase General function prediction only 50121455 Common - putative lipoprotein ECA2531 24 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 50120072 Common xseB exodeoxyribonuclease VII small subunit ECA1133 30 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 50122345 Common - Rhs protein ECA3421 64 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 50123118 Common - putative exported phosphatase ECA4198 17 None None None 50122927 Common rpsD 30S ribosomal protein S4 ECA4007 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 50120413 Common - hypothetical protein ECA1475 31 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 50120043 Common - hypothetical protein ECA1104 52 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 50119182 Common rplL 50S ribosomal protein L7/L12 ECA0222 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 50121569 Common - recombination factor protein RarA ECA2645 225 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 50122176 Common glnB nitrogen regulatory protein P-II ECA3254 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 50123002 Common occQ octopine transport system permease protein ECA4082 165 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 50120132 Common copA copper transporter ECA1193 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 50120333 Common modB molybdate ABC transporter permease protein ECA1394 235 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 50119701 Common - hypothetical protein ECA0756 43 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 50120990 Common - putative phosphatase ECA2062 42 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 50121561 Common - phage repressor protein C ECA2636 7 COG1395 COG1395, Predicted transcriptional regulator Transcription 50120051 Common - putative phosphate binding protein ECA1112 107 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 50123065 Common - hypothetical protein ECA4145 2 None None None 50119717 Common recJ ssDNA exonuclease RecJ ECA0772 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 50121483 Common - transposase for the IS1541 insertion element ECA2559 70 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 50121571 Common ftsK cell division protein ECA2647 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 50119247 Common - putative sigma(54) modulation protein ECA0287 141 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 50121411 Common znuB high-affinity zinc transporter membrane component ECA2486 170 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 50121918 Common nasF nitrate-binding proteint ECA2994 78 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 50118968 Common asnA asparagine synthetase AsnA ECA0003 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 50120213 Common - RNA polymerase sigma factor ECA1274 47 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50120697 Pathogen - hypothetical protein ECA1764 3 None None None 50121700 Common - hypothetical protein ECA2776 10 None None None 50120931 Common - putative lipoprotein ECA2004 26 None None None 50121930 Common - hypothetical protein ECA3007 62 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 50122171 Common hcaT putative 3-phenylpropionic acid transporter ECA3249 73 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119452 Common - putative capsular polysaccharide export protein ECA0501 110 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 50120314 Common - hypothetical protein ECA1375 104 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 50122036 Common outB general secretion pathway protein ECA3113 7 None None None 50122522 Common cysQ PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase ECA3601 153 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 50122182 Common - tRNA-specific adenosine deaminase ECA3260 214 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 50121472 Common mukE condesin subunit E ECA2548 20 COG3095 MukE, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 50123290 Common bcsB cellulose synthase regulator protein ECA4372 20 None None None 50119125 Common waaF ADP-heptose:LPS heptosyltransferase II ECA0164 103 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 50122930 Common rpmJ 50S ribosomal protein L36 ECA4010 138 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 50120513 Common - 2-dehydropantoate 2-reductase ECA1579 48 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 50120391 Common - putative beta-glucoside operon antiterminator ECA1452 29 COG3711 BglG, Transcriptional antiterminator Transcription 50122672 Common - hypothetical protein ECA3750 5 None None None 50119581 Common zur zinc uptake transcriptional repressor ECA0632 156 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 50121166 Common - hypothetical protein ECA2238 13 None None None 50120257 Common - PhoH-like ATP-binding protein ECA1318 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 50122864 Pathogen - putative phage-related protein ECA3944 1 None None None 50119925 Common nudH dinucleoside polyphosphate hydrolase ECA0985 117 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 50121385 Common prc carboxy-terminal protease ECA2459 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 50119006 Common - phosphoethanolamine transferase ECA0044 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 50122311 Common - hypothetical protein ECA3387 4 None None None 50122861 Common ahpF alkyl hydroperoxide reductase subunit F ECA3941 245 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 50122284 Common luxS S-ribosylhomocysteinase ECA3362 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 50119204 Common aapQ L-amino acid ABC transporter permease protein ECA0244 171 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50123364 Common trmE tRNA modification GTPase TrmE ECA4446 229 COG0486 ThdF, Predicted GTPase General function prediction only 50121733 Common cbrA achromobactin-binding periplasmic protein ECA2809 74 COG4594 FecB, ABC-type Fe3+-citrate transport system, periplasmic component Inorganic ion transport and metabolism 50122143 Common - hypothetical protein ECA3221 34 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 50120065 Common ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ECA1126 223 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 50119520 Pathogen - hypothetical protein ECA0571 1 None None None 50123414 Common - putative thioesterase ECA4498 64 COG0824 FcbC, Predicted thioesterase General function prediction only 50119264 Common - cytochrome d ubiquinol oxidase subunit III ECA0304 27 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 50122249 Common - carbonic anhydrase ECA3327 121 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 50119529 Common - hypothetical protein ECA0580 23 None None None 50121205 Common rnfB electron transport complex protein RnfB ECA2277 121 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 50121831 Pathogen - hypothetical protein ECA2907 2 None None None 50121939 Common nuoN NADH dehydrogenase subunit N ECA3016 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 50119710 Common - hypothetical protein ECA0765 8 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 50119016 Common - putative methyltransferase ECA0054 49 None None None 50121549 Common - phage capsid portal protein Q ECA2624 24 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 50122792 Common carA carbamoyl phosphate synthase small subunit ECA3871 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 50119490 Common pilT putative Type IV pilus protein ECA0542 28 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 50122107 Common mdtB multidrug efflux system subunit MdtB ECA3185 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 50119488 Common pilR putative Type IV pilus protein ECA0540 11 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 50121578 Common - GntR-family transcriptional regulator ECA2654 180 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50122904 Common - putative sodium:sulfate symporter ECA3984 104 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 50120772 Common - hypothetical protein ECA1842 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 50121184 Common - putative transporter ECA2256 229 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50120586 Pathogen - hypothetical protein ECA1654 6 None None None 50123381 Common - putative permease ECA4464 135 COG2252 COG2252, Permeases General function prediction only 50121098 Common - hypothetical protein ECA2170 18 COG4639 COG4639, Predicted kinase General function prediction only 50123359 Common dnaA chromosomal replication initiation protein ECA4441 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 50119585 Common - hypothetical protein ECA0636 39 COG2259 COG2259, Predicted membrane protein Function unknown 50119479 Pathogen - hypothetical protein ECA0527 1 None None None 50121513 Common hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein ECA2589 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 50122889 Common frdA fumarate reductase flavoprotein subunit ECA3969 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 50123405 Common - putative extracellular solute-binding protein ECA4489 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50122333 Common - hypothetical protein ECA3409 7 None None None 50119847 Common - LysR-family transcriptional regulator ECA0905 172 COG0583 LysR, Transcriptional regulator Transcription 50119379 Common - putative porin ECA0428 146 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 50121913 Common nirE uroporphyrin-III C-methyltransferase ECA2989 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 50122949 Common rplW 50S ribosomal protein L23 ECA4029 176 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 50120000 Common - putative integrase ECA1060 16 None None None 50120779 Common - GntR-family transcriptional regulator ECA1849 140 COG2188 PhnF, Transcriptional regulators Transcription 50122090 Common ohrR transcriptional regulator of organic hydroperoxide resistance gene ohr ECA3168 130 COG1846 MarR, Transcriptional regulators Transcription 50119967 Common - hypothetical protein ECA1027 17 None None None 50122108 Common mdtC multidrug efflux system subunit MdtC ECA3186 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 50120614 Common - hypothetical protein ECA1680 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 50119265 Common - putative ATP/GTP-binding protein ECA0305 102 COG1485 COG1485, Predicted ATPase General function prediction only 50120595 Pathogen - hypothetical protein ECA1663 3 None None None 50122582 Common pspG phage shock protein G ECA3661 10 None None None 50120612 Common - hypothetical protein ECA1678 2 None None None 50121669 Common rplY 50S ribosomal protein L25 ECA2745 135 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 50121806 Common expA response regulator ECA2882 201 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50119563 Common - hypothetical protein ECA0613 24 None None None 50122088 Pathogen - hypothetical protein ECA3166 1 None None None 50121325 Common yfeE hypothetical protein ECA2397 13 None None None 50119373 Common - hypothetical protein ECA0422 57 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 50121698 Common - hypothetical protein ECA2774 6 None None None 50119758 Common - hypothetical protein ECA0815 18 COG0628 PerM, Predicted permease General function prediction only 50121160 Common - probable hydrolase ECA2233 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 50119697 Common - probable sugar ABC transporter, periplasmic binding protein ECA0752 115 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50120589 Common - hypothetical protein ECA1657 4 None None None 50121104 Pathogen - hypothetical protein ECA2176 4 None None None 50119197 Common - putative lipoprotein ECA0237 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 50122883 Pathogen - hypothetical protein ECA3963 1 None None None 50122190 Common - putative toxin secretion ATP-binding protein ECA3268 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 50122278 Common rplS 50S ribosomal protein L19 ECA3356 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 50121157 Common - putative NADH-dependent flavin oxidoreductase ECA2230 176 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 50120348 Common metG methionyl-tRNA synthetase ECA1409 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50120945 Common - short chain dehydrogenase ECA2018 224 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50119871 Common - biopolymer transport protein ECA0929 31 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 50121730 Common cbrD achromobactin transport ATP-binding protein ECA2806 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 50121929 Common - hypothetical protein ECA3006 10 None None None 50121628 Common - short chain dehydrogenase ECA2704 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 50120855 Common purR DNA-binding transcriptional repressor PurR ECA1925 129 COG1609 PurR, Transcriptional regulators Transcription 50120338 Common - hypothetical protein ECA1399 64 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 50120692 Common - putative CoA binding protein ECA1759 134 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 50119908 Common - putative short chain dehydrogenase ECA0968 128 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 50119868 Common - putative biopolymer transport protein ECA0926 28 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 50119378 Common - LysR-family transcriptional regulator ECA0427 156 COG0583 LysR, Transcriptional regulator Transcription 50122223 Common degP serine endoprotease ECA3301 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 50123400 Pathogen - hypothetical protein ECA4484 1 None None None 50121086 Common - hypothetical protein ECA2158 57 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 50119794 Common - putative sugar ABC transporter ATP-binding protein ECA0851 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 50122361 Common - hypothetical protein ECA3438 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 50123437 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA ECA4521 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 50119765 Common - putative carbon-nitrogen hydrolase ECA0822 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 50120557 Common - hypothetical protein ECA1623 5 None None None 50120965 Common - OsmC-like protein ECA2037 41 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 50119946 Common - ABC transporter, permease protein ECA1006 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122185 Common - hypothetical protein ECA3263 34 COG3672 COG3672, Predicted periplasmic protein Function unknown 50120463 Common tauA putative taurine-binding periplasmic protein ECA1528 106 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 50120999 Common - putative cytochrome P450 ECA2071 70 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 50120098 Common mdlB putative multidrug transporter membrane\ATP-binding components ECA1159 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 50121138 Common - putative cyclopropane-fatty-acyl-phospholipid synthase ECA2212 124 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 50122008 Common - hypothetical protein ECA3085 5 None None None 50119146 Common - hypothetical protein ECA0186 49 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 50120448 Common - putative permease ECA1513 198 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 50122803 Common dnaK molecular chaperone DnaK ECA3882 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 50121446 Common mviM putative virulence factor ECA2522 81 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 50121882 Common - putative sulfate transporter ECA2958 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 50122511 Common folB bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase ECA3590 103 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 50120628 Common cheY chemotaxis regulator transmitting signal to flagellar motor component ECA1694 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 50120326 Common - hypothetical protein ECA1387 4 None None None 50121680 Common - hypothetical protein ECA2756 4 None None None 50119980 Common ompH periplasmic chaperone ECA1040 78 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 50119096 Common - ABC transporter permease protein ECA0135 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121305 Common - hypothetical protein ECA2377 16 COG3140 COG3140, Uncharacterized protein conserved in bacteria Function unknown 50119517 Common - hypothetical protein ECA0568 19 None None None 50121687 Common - probable transport protein ECA2763 76 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 50121754 Common cdd cytidine deaminase ECA2830 24 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 50121460 Common - putative iron-sulfur binding protein ECA2536 60 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 50120402 Common - putative carbohydrate kinase ECA1463 143 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 50121467 Common aspC aromatic amino acid aminotransferase ECA2543 72 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 50123229 Common sotB sugar efflux transporter ECA4309 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50121947 Common nuoF NADH dehydrogenase I subunit F ECA3024 168 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 50122741 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase ECA3819 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 50122258 Common nrdI ribonucleotide reductase stimulatory protein ECA3336 35 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 50121598 Common potI putrescine transporter subunit: membrane component of ABC superfamily ECA2674 179 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 50122476 Common meh metallo hydrolase ECA3555 93 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 50121060 Common - hypothetical protein ECA2132 11 COG0388 COG0388, Predicted amidohydrolase General function prediction only 50122748 Common - DNA-binding transcriptional regulator FruR ECA3827 122 COG1609 PurR, Transcriptional regulators Transcription 50123038 Common greB transcription elongation factor GreB ECA4118 195 COG0782 GreA, Transcription elongation factor Transcription 50123265 Common ftsE cell division protein FtsE ECA4345 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 50120568 Pathogen - hypothetical protein ECA1636 2 None None None 50122771 Common - hypothetical protein ECA3850 135 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 50120395 Common - putative aldehyde dehydrogenase ECA1456 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50123104 Pathogen - putative lipoprotein ECA4184 1 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 50122041 Common - putative mechanosensitive ion channel protein ECA3118 200 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 50120184 Common hyfC hydrogenase-4 component C ECA1245 73 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 50121775 Common mvpT putative plasmid protein ECA2851 21 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 50123386 Common - extracellular solute-binding protein ECA4470 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50120823 Common napB diheme cytochrome c550 ECA1893 39 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 50122084 Common pstA phosphate ABC transporter permease protein ECA3162 217 COG4985 COG4985, ABC-type phosphate transport system, auxiliary component Inorganic ion transport and metabolism 50123091 Common rhtC threonine efflux system ECA4171 115 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 50120375 Common rfbU putative glycosyl transferase ECA1436 165 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 50119595 Common uxaB1 altronate oxidoreductase ECA0646 84 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 50121323 Common yfeD chelated iron transport system membrane protein ECA2395 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 50123261 Common livK leucine-specific binding protein ECA4341 132 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 50123093 Common pldA phospholipase A ECA4173 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 50119880 Common - hypothetical protein ECA0938 3 None None None 50119889 Common - hypothetical protein ECA0947 8 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 50120470 Common hasE HlyD family secretion protein ECA1535 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 50122597 Pathogen - hypothetical protein ECA3676 2 None None None 50120672 Common fliA flagellar biosynthesis sigma factor ECA1739 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 50121536 Common - baseplate assembly protein V ECA2612 27 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 50122071 Common - putative regulator ECA3148 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 50121845 Common - hypothetical protein ECA2921 8 None None None 50120796 Common lpp major outer membrane lipoprotein ECA1866 19 COG4238 COG4238, Murein lipoprotein Cell envelope biogenesis, outer membrane 50119641 Common obgE GTPase ObgE ECA0693 249 COG0536 Obg, Predicted GTPase General function prediction only 50122937 Common rpsH 30S ribosomal protein S8 ECA4017 246 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 50119630 Common rpsU 30S ribosomal protein S21 ECA0682 153 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 50118972 Common qseC sensor protein QseC ECA0007 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50122705 Common - AraC-family transcriptional regulator ECA3783 63 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50122981 Common - hypothetical protein ECA4061 31 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 50121820 Common - hypothetical protein ECA2896 8 None None None 50120248 Common leuS leucyl-tRNA synthetase ECA1309 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50121864 Common nifF flavodoxin FldA ECA2940 64 COG0716 FldA, Flavodoxins Energy production and conversion 50121958 Common - putative sodium/sulphate transporter ECA3035 138 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 50120921 Pathogen - hypothetical protein ECA1994 1 None None None 50120711 Common opgH glucosyltransferase MdoH ECA1778 53 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 50121543 Common - phage tail protein X ECA2618 17 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 50121142 Common - hypothetical protein ECA2216 25 None None None 50122139 Common - outer membrane protein assembly complex subunit YfgL ECA3217 120 COG1520 COG1520, FOG: WD40-like repeat Function unknown 50123423 Common - putative lipoprotein ECA4507 12 None None None 50121838 Pathogen - hypothetical protein ECA2914 1 None None None 50122292 Common - competence damage-inducible protein A ECA3370 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 50123183 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase ECA4263 91 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 50120502 Common - putative lipoprotein ECA1567 12 None None None 50119558 Pathogen cfa1 Cfa-acyl carrier protein ECA0608 2 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50119835 Common ptsH phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr) ECA0893 138 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 50120123 Common ushA bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ECA1184 140 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 50121581 Common clpS ATP-dependent Clp protease adaptor protein ClpS ECA2657 120 COG2127 COG2127, Uncharacterized conserved protein Function unknown 50121005 Common hrcT type III secretion protein ECA2077 27 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 50122110 Common baeS signal transduction histidine-protein kinase BaeS ECA3188 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50122217 Common - hypothetical protein ECA3295 29 COG2259 COG2259, Predicted membrane protein Function unknown 50120664 Common fliC flagellin ECA1731 126 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 50121792 Common - hypothetical protein ECA2868 8 COG5435 COG5435, Uncharacterized conserved protein Function unknown 50121869 Common nifS cysteine desulfurase ECA2945 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 50120479 Common - putative methyltransferase ECA1544 37 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50120884 Common - hypothetical protein ECA1956 64 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 50120499 Common - putative paraquat-inducible protein ECA1564 64 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 50119687 Common fucO L-1,2-propanediol oxidoreductase ECA0742 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 50119613 Common - putative phage integrase ECA0665 60 COG0582 XerC, Integrase DNA replication, recombination, and repair 50122168 Common - putative periplasmic substrate-binding transport protein ECA3246 94 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50121007 Common hrcR type III secretion system protein ECA2079 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 50121743 Common - hypothetical protein ECA2819 5 None None None 50119034 Common - ABC transporter ATP-binding protein ECA0072 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 50120920 Common zntB zinc transporter ECA1993 133 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 161501884 Common gltB glutamate synthase subunit alpha ECA0312 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 50119068 Common pmeB pectin methylesterase ECA0107 18 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 50119257 Common vpsC hypothetical protein ECA0297 92 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 50120780 Common palI sucrose isomerase ECA1850 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 50122024 Common outL general secretion pathway protein L ECA3101 31 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 50121228 Common trpB tryptophan synthase subunit beta ECA2300 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 50121920 Common - bacteriophage tail fiber protein ECA2996 22 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 50121190 Common fumC fumarate hydratase ECA2262 223 COG0114 FumC, Fumarase Energy production and conversion 50123082 Common - hypothetical protein ECA4162 144 COG1741 COG1741, Pirin-related protein General function prediction only 50120634 Common flgM anti-sigma28 factor FlgM ECA1700 16 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 50120763 Common btuE predicted glutathione peroxidase ECA1833 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 50122546 Common - hypothetical protein ECA3625 194 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 50122323 Common xerC site-specific tyrosine recombinase XerC ECA3399 214 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50119789 Common gldA glycerol dehydrogenase ECA0846 133 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 50122306 Pathogen - hypothetical protein ECA3382A 1 None None None 50120296 Common sdhC succinate dehydrogenase cytochrome b556 large membrane subunit ECA1357 89 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 50122242 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ECA3320 198 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 50123144 Common - hypothetical protein ECA4224 28 COG5587 COG5587, Uncharacterized conserved protein Function unknown 50121879 Common nifD nitrogenase molybdenum-iron protein alpha chain ECA2955 50 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 50122814 Common arcA DNA-binding response regulator in two-component regulatory system with ArcB or CpxA ECA3893 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50120654 Common fliK flagellar hook-length control protein ECA1721 49 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 50121618 Common - putative polyketide synthetase ECA2694 212 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50123211 Common - DnaG primase-like protein ECA4291 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 50119506 Common - hypothetical protein ECA0557 22 None None None 50120161 Common tesA multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 ECA1222 102 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 50121981 Common truA tRNA pseudouridine synthase A ECA3058 234 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 50119446 Common phnL putative phosphonate ABC transporter ATP-binding protein ECA0495 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 50122692 Common qacH quaternary ammonium compound resistance protein ECA3770 109 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 161501883 Common tolC outer membrane channel protein ECA0330 124 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50120146 Common - probable short chain dehydrogenase ECA1207 220 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 50123315 Common - hypothetical protein ECA4397 3 None None None 50122848 Common mpl udp-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase ECA3928 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 50119240 Common - succinate-semialdehyde dehydrogenase [NADP+] ECA0280 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 50122029 Common outG general secretion pathway protein G ECA3106 104 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 50120320 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase ECA1381 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 50119760 Common togT oligogalacturonide transporter ECA0817 75 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 50121218 Common btuR cob(I)yrinic acid a,c-diamide adenosyltransferase ECA2290 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 50123431 Common atpH F0F1 ATP synthase subunit delta ECA4515 176 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 50119785 Common grpE heat shock protein ECA0842 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 50119987 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha ECA1047 194 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 50123089 Common pldB lysophospholipase L2 ECA4169 67 COG2267 PldB, Lysophospholipase Lipid metabolism 50120202 Common nlpB lipoprotein ECA1263 24 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 50121112 Common - predicted inner membrane protein ECA2185 10 None None None 50121623 Common ehpD putative phenazine antibiotic biosynthesis protein ECA2699 104 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 50123191 Common - hypothetical protein ECA4271 11 None None None 50122408 Common - hypothetical protein ECA3487 117 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 50122969 Common fkpA FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) ECA4049 137 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 50119133 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase ECA0173 213 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 50122158 Common icsU scaffold protein ECA3236 152 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 50120222 Common atoA acetate CoA-transferase beta subunit ECA1283 98 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 50122075 Common - hypothetical protein ECA3152 31 COG2259 COG2259, Predicted membrane protein Function unknown 50121801 Common - hypothetical protein ECA2877 2 None None None 50120908 Common celV endoglucanase V ECA1981 22 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 50119335 Common - hypothetical protein ECA0376 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 50120814 Common ccmC heme exporter protein C ECA1884 122 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 50122942 Common rpsQ 30S ribosomal protein S17 ECA4022 237 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 50119678 Common rimI ribosomal-protein-alanine N-acetyltransferase ECA0733 134 COG0456 RimI, Acetyltransferases General function prediction only 50122498 Common gudP probable glucarate transporter ECA3577 197 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50123316 Common dcuR DNA-binding response regulator in two-component regulatory system with DcuS ECA4398 190 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 50123253 Common - methyl-accepting chemotaxis protein ECA4333 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50122810 Common thrC threonine synthase ECA3889 157 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 50120028 Common - hypothetical protein ECA1088 14 None None None 50123153 Common - inner membrane ABC transporter permease protein YjfF ECA4233 113 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 161501871 Common hpt hypoxanthine-guanine phosphoribosyltransferase ECA3328 153 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 50123137 Common putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase ECA4217 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 50120703 Common - hypothetical protein ECA1770 57 COG1683 COG1683, Uncharacterized conserved protein Function unknown 50122678 Common - ABC transporter ATP-binding protein ECA3756 236 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 50119077 Common - putative fatty acid desaturase ECA0116 12 COG3239 DesA, Fatty acid desaturase Lipid metabolism 50119192 Common thiE thiamine-phosphate pyrophosphorylase ECA0231 205 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 50120110 Common acrR DNA-binding transcriptional repressor ECA1171 135 COG1309 AcrR, Transcriptional regulator Transcription 50121121 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase ECA2194 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 50120882 Common - putative transcriptional regulator ECA1954 69 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 50120761 Common - putative methyltransferase ECA1831 165 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50120514 Common - putative cold-shock protein ECA1580 7 COG1278 CspC, Cold shock proteins Transcription 50119070 Common - hypothetical protein ECA0109 203 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 50120544 Pathogen - hypothetical plasmid protein ECA1611 4 None None None 50122149 Common sseA 3-mercaptopyruvate sulfurtransferase ECA3227 141 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 50122508 Common - putative signal transduction protein ECA3587 30 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 50119773 Pathogen - hypothetical protein ECA0830 1 None None None 50121082 Common - putative ABC transporter, permease ECA2154 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50122276 Common - hypothetical protein ECA3354 6 None None None 50123078 Common gntP gluconate permease ECA4158 78 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 50119615 Pathogen - hypothetical protein ECA0667 1 None None None 50119360 Common valS valyl-tRNA synthetase ECA0402 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50120300 Common kgd alpha-ketoglutarate decarboxylase ECA1361 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 50121441 Pathogen - hypothetical protein ECA2517 1 None None None 50120475 Common - ECF sigma factor ECA1540 30 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50122855 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase ECA3935 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 50122485 Common - iron-chelating periplasmic-binding protein ECA3564 67 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 50121043 Common - putative transcriptional regulator ECA2115 99 COG1802 GntR, Transcriptional regulators Transcription 50123146 Common ilvD dihydroxy-acid dehydratase ECA4226 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 50119496 Pathogen - hypothetical protein ECA0547 3 None None None 50122726 Common - hypothetical protein ECA3804 58 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 50122769 Common ilvB acetolactate synthase catalytic subunit ECA3848 223 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 50119098 Common - ABC transporter periplasmic binding protein ECA0137 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50119712 Pathogen - hypothetical protein ECA0767 4 None None None 50121331 Common togM binding-protein-dependent transport system, inner membrane component ECA2403 168 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 50122732 Common ftsZ cell division protein FtsZ ECA3810 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 50119380 Common - hypothetical protein ECA0429 4 None None None 50122801 Common nhaA Na(+)/H(+) antiporter 1 ECA3880 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 50122832 Common fbaA fructose-bisphosphate aldolase ECA3911 171 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 50122196 Common acpS 4'-phosphopantetheinyl transferase ECA3274 137 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 50122716 Common ampE regulatory protein AmpE ECA3794 14 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 50120519 Common - hypothetical protein ECA1585 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 50120839 Common katB catalase-peroxidase ECA1909 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 50122351 Common - hypothetical protein ECA3427 58 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 50119934 Common ptrA protease III precursor ECA0994 188 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 50122392 Common - putative DNA-binding protein ECA3469 43 COG1396 HipB, Predicted transcriptional regulators Transcription 50120421 Common - putative NAD(P)H oxidoreductase ECA1483 75 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 50121725 Common - periplasmic dipeptide transport protein ECA2801 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 50121552 Common - putative phage replication protein A ECA2627 18 None None None 50119109 Common mutM formamidopyrimidine-DNA glycosylase ECA0148 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 50122015 Common dbpA ATP-dependent RNA helicase DbpA ECA3092 231 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 50120735 Common tdk thymidylate kinase ECA1802 230 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 50119414 Common nadR nicotinamide-nucleotide adenylyltransferase ECA0463 32 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 50122358 Common - putative sigma-54 dependent transcriptional regulator ECA3435 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 50122135 Common - AraC-family transcriptional regulator ECA3213 93 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50120555 Common virB2 putative conjugal transfer protein ECA1621 5 None None None 50123159 Common trmA tRNA (uracil-5-)-methyltransferase ECA4239 164 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 50123250 Common - putative isomerase ECA4330 78 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 50119719 Common lysS lysyl-tRNA synthetase ECA0774 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 50119795 Common - putative exported plant proteoglycan hydrolase ECA0852 29 COG3867 COG3867, Arabinogalactan endo-1,4-beta-galactosidase Carbohydrate transport and metabolism 50120625 Common cheD methyl-accepting chemotaxis protein ECA1691 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 50120409 Common - ABC transporter, substrate binding protein ECA1470 114 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 50123425 Common glmU bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase ECA4509 229 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 50122919 Common def peptide deformylase ECA3999 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 50121954 Pathogen - hypothetical protein ECA3031 1 None None None 50122327 Pathogen - hypothetical protein ECA3403 2 None None None 50119286 Common - hypothetical protein ECA0327 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 50120130 Common - hypothetical protein ECA1191 116 COG2606 EbsC, Uncharacterized conserved protein Function unknown 50119979 Common ecfK outer membrane protein assembly factor YaeT ECA1039 159 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 50120439 Common - LysR-family transcriptional regulator ECA1501 147 COG0583 LysR, Transcriptional regulator Transcription 50119802 Common - PTS system, IIabc component ECA0860 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50123267 Common - predicted methyltransferase ECA4347 205 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 50123157 Common murI glutamate racemase ECA4237 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 50119970 Common map methionine aminopeptidase ECA1030 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 50119996 Common - putative phage-related reverse transcriptase/maturase family protein ECA1056 5 None None None 50122043 Common hsdS subunit S of type I restriction-modification system ECA3120 58 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 50121518 Common serC phosphoserine aminotransferase ECA2594 115 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 50123141 Common ilvC ketol-acid reductoisomerase ECA4221 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 50119224 Common - putative sulfite oxidase subunit YedY ECA0264 125 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 50121310 Common - putative NADP oxidoreductase coenzyme F420-dependent protein ECA2382 72 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 50122436 Common - putative lipoprotein ECA3515 17 None None None 50119875 Common - LuxR-family transcriptional regulator ECA0933 12 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50119211 Common - endonuclease/Exonuclease/phosphatase family protein ECA0251 15 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 50121817 Common hns3 DNA-binding protein Hns ECA2893 27 COG2916 Hns, DNA-binding protein H-NS General function prediction only 50121419 Common - hypothetical protein ECA2494 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 50122113 Common - putative acetyltransferase ECA3191 141 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 50122263 Common - hypothetical protein ECA3341 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50120981 Common gabT 4-aminobutyrate aminotransferase ECA2053 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 50121264 Common - hypothetical protein ECA2336 9 None None None 50121874 Common - TetR-family regulatory protein ECA2950 81 COG1309 AcrR, Transcriptional regulator Transcription 50118995 Common dtd D-tyrosyl-tRNA deacylase ECA0032 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 50119841 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase ECA0899 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 50120032 Common uxuA mannonate dehydratase ECA1093 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 50123401 Common aatA aspartate aminotransferase ECA4485 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 50120118 Common htpG heat shock protein 90 ECA1179 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 50122565 Common - GntR-family transcriptional regulator ECA3644 137 COG2186 FadR, Transcriptional regulators Transcription 50120210 Common - biopolymer transport protein ECA1271 144 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 50122808 Common talB transaldolase B ECA3887 182 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 50120573 Pathogen - hypothetical protein ECA1641 1 None None None 50121011 Common hrcN type III secretion protein ECA2083 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 50123128 Common wecB UDP-N-acetylglucosamine 2-epimerase ECA4208 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 50122210 Common - autonomous glycyl radical cofactor GrcA ECA3288 51 COG3445 COG3445, Acid-induced glycyl radical enzyme General function prediction only 50119665 Common deaD ATP-dependent RNA helicase DeaD ECA0718 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 50121550 Common - phage DNA methylase ECA2625 17 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 50119298 Common - probable sugar-bisphosphate aldolase ECA0339 169 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 50122607 Common mcK putative plasmid-related protein ECA3686 52 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 50120377 Common rfbM mannose-1-phosphate guanylyltransferase ECA1438 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 50122452 Common nlpD predicted outer membrane lipoprotein ECA3531 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 50119893 Common - probable NAD(P)H oxidoreductase ECA0951 80 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 50122082 Pathogen - putative transcriptional regulator ECA3160 3 None None None 50120426 Common - non-ribosomal peptide synthetase ECA1488 224 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50118981 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B ECA0016 104 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 50119547 Common - hypothetical protein ECA0597 47 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 50121238 Pathogen - hypothetical protein ECA2310 2 None None None 50122128 Common - transcriptional regulator ECA3206 23 COG3423 Nlp, Predicted transcriptional regulator Transcription 50121291 Pathogen - DNA polymerase III, theta subunit ECA2363 2 None None None 50121202 Common araB ribulokinase ECA2274 68 COG1069 AraB, Ribulose kinase Energy production and conversion 50119767 Common - pyruvate-flavodoxin oxidoreductase ECA0824 115 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 50121660 Common - putative ABC transporter, periplasmic binding protein ECA2736 157 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 50121185 Common bioD putative dithiobiotin synthetase ECA2257 108 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 50121159 Common - LysR-family transcriptional regulator ECA2232 186 COG0583 LysR, Transcriptional regulator Transcription 50122312 Pathogen - hypothetical protein ECA3388 1 None None None 50122978 Common - putative ABC transporter ATP-binding protein ECA4058 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 50119955 Common gcvA DNA-binding transcriptional activator GcvA ECA1015 184 COG0583 LysR, Transcriptional regulator Transcription 50123022 Common igaA intracellular growth attenuator protein ECA4102 11 None None None 50122461 Common - hypothetical protein ECA3540 10 None None None 50120864 Common - putative lipoprotein ECA1934 14 COG3895 COG3895, Predicted periplasmic protein General function prediction only 50121853 Common - putative efflux protein ECA2929 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 50120440 Common gltP proton glutamate symport protein ECA1503 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 50121813 Common intB integrase ECA2889 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 50119661 Common truB tRNA pseudouridine synthase B ECA0714 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 50120054 Common proY proline-specific permease ECA1115 170 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 50121049 Pathogen - hypothetical protein ECA2121 3 None None None 50121783 Pathogen - hypothetical protein ECA2859 1 None None None 50121638 Common adhC alcohol dehydrogenase class III ECA2714 190 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 50121371 Common purB adenylosuccinate lyase ECA2444 231 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 50120198 Common - hypothetical protein ECA1259 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 50120481 Common proP proline/glycine betaine transporter ECA1546 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122751 Common - putative AMP-binding protein ECA3830 211 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 50119709 Pathogen - hypothetical protein ECA0764 1 None None None 50120352 Common asmA putative assembly protein ECA1413 38 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 50123299 Common - putative DNA-binding protein ECA4381 42 COG1802 GntR, Transcriptional regulators Transcription 50119627 Common mug G/U mismatch-specific DNA glycosylase ECA0679 29 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 50120675 Common - hypothetical protein ECA1742 23 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 50119156 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase ECA0196 223 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 50119960 Common queF 7-cyano-7-deazaguanine reductase ECA1020 75 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 50120492 Common atsB putative sulfate ester transporter, permease component ECA1557 184 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50120537 Common arsB arsenical pump membrane protein ECA1604 108 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 50120878 Common - putative transketolase N-terminal section ECA1950 222 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 50122010 Common - hypothetical protein ECA3087 6 None None None 50122617 Common - putative phage regluatory protein ECA3696 21 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 50121365 Common - putative electron transport protein ECA2438 100 COG0348 NapH, Polyferredoxin Energy production and conversion 50122031 Common outE general secretion pathway protein E ECA3108 221 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 50120416 Common - AraC-family transcriptional regulator ECA1478 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50122654 Common - putative bacteriophage tail protein (Tape-measure) ECA3732 40 COG5283 COG5283, Phage-related tail protein Function unknown 50119438 Common fom1 phosphoenolpyruvate phosphomutase ECA0487 94 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 50119244 Common ptsO phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) ECA0284 129 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 50121428 Pathogen - putative phage-related protein ECA2503 1 None None None 50119756 Common - RNA polymerase sigma factor ECA0813 64 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 50122537 Common - hypothetical protein ECA3616 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 50123373 Common - hypothetical protein ECA4455 37 COG2378 COG2378, Predicted transcriptional regulator Transcription 50119500 Pathogen - hypothetical protein ECA0551 1 None None None 50120037 Common - putative type I secretion protein ECA1098 138 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50123249 Common - putative aldolase ECA4329 118 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 50119319 Common scrR sucrose operon repressor ECA0360 125 COG1609 PurR, Transcriptional regulators Transcription 50122786 Common - hypothetical protein ECA3865 30 COG3610 COG3610, Uncharacterized conserved protein Function unknown 50120013 Common fecE iron-dicitrate transporter ATP-binding subunit ECA1073 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 50119431 Common entF enterobactin synthetase component F ECA0480 216 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 50122280 Common rimM 16S rRNA-processing protein ECA3358 174 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 50120137 Common nrdB ribonucleotide-diphosphate reductase subunit beta ECA1198 153 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 50122406 Common - oxidase ECA3485 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 50119024 Common gor glutathione reductase ECA0062 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 50119134 Common cysE serine acetyltransferase ECA0174 212 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 50118986 Common polA DNA polymerase I ECA0021 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 50121804 Common pgsA phosphatidylglycerophosphate synthetase ECA2880 197 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 50119102 Common pyrE orotate phosphoribosyltransferase ECA0141 145 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 50122584 Common qor quinone oxidoreductase, NADPH-dependent ECA3663 179 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 50122951 Common rplC 50S ribosomal protein L3 ECA4031 232 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 50119180 Common rplA 50S ribosomal protein L1 ECA0220 226 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 50123205 Pathogen - hypothetical protein ECA4285 1 None None None 50123026 Common pckA phosphoenolpyruvate carboxykinase ECA4106 97 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 50121762 Common - hypothetical protein ECA2838 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 50119340 Common pyrI aspartate carbamoyltransferase regulatory subunit ECA0381 62 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 50119408 Common visC hypothetical protein ECA0457 136 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 50121280 Common - putative 6-phosphofructokinase isozyme II ECA2352 144 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 50119753 Pathogen hexY global regulatory protein ECA0809 1 None None None 50119815 Common - hypothetical protein ECA0873 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 50119189 Common thiG thiazole synthase ECA0229 167 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 50122879 Common - ArsR-family transcriptional regulator ECA3959 34 COG0640 ArsR, Predicted transcriptional regulators Transcription 50119063 Common - hypothetical protein ECA0102 74 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 50120465 Common tauB putative taurine transport ATP-binding protein ECA1530 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50120911 Common pspB phage shock protein B ECA1984 22 None None None 50123055 Common malQ 4-alpha-glucanotransferase ECA4135 118 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 50122877 Common - putative hydrolase ECA3957 50 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 50120046 Common - fructokinase ECA1107 170 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 50120459 Common - ABC transporter permease protein ECA1524 157 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 50123036 Common - putative siderophore biosynthesis protein ECA4116 50 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 50122330 Common xerC site-specific tyrosine recombinase XerC ECA3406 221 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50120599 Common - putative type IV pilin protein precursor ECA1667 9 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 50122579 Common - hypothetical protein ECA3658 5 None None None 50120725 Common - hypothetical protein ECA1792 53 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 50120411 Common - hypothetical protein ECA1472 7 None None None 50120070 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase ECA1131 222 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 50120952 Pathogen - hypothetical protein ECA2024 1 None None None 50122553 Common - coproporphyrinogen III oxidase ECA3632 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 50122470 Common - putative signaling protein ECA3549 159 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 50119736 Common - hypothetical protein ECA0791 27 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 50121053 Pathogen - hypothetical protein ECA2125 1 None None None 50123166 Common - putative sugar binding transcriptional regulator ECA4246 122 COG1609 PurR, Transcriptional regulators Transcription 50120053 Common brnQ branched-chain amino acid transport system II carrier protein ECA1114 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 50120194 Common upp uracil phosphoribosyltransferase ECA1255 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 50122631 Common - putative phage-related lipoprotein ECA3710 3 None None None 50120365 Common - putative thiamine pyrophosphate enzyme ECA1426 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 50120667 Common - hypothetical protein ECA1734 34 None None None 50121115 Common lolB outer membrane lipoprotein LolB ECA2188 40 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 50119556 Common cfa3 Cfa-beta-ketoacylsynthase ECA0606 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50121453 Common - putative hydrolase ECA2529 58 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 50122892 Common frdD fumarate reductase subunit D ECA3972 23 COG3080 FrdD, Fumarate reductase subunit D Energy production and conversion 50121784 Common - hypothetical protein ECA2860 44 COG3596 COG3596, Predicted GTPase General function prediction only 50121702 Common - hypothetical protein ECA2778 4 None None None 50121744 Common uvrB excinuclease ABC subunit B ECA2820 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 50119621 Common - putative phage-related DNA binding protein ECA0673 9 COG1396 HipB, Predicted transcriptional regulators Transcription 50120452 Common - hypothetical protein ECA1517 29 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 50120632 Common flhE flagellar protein ECA1698 9 None None None 50122208 Common - hypothetical protein ECA3286 30 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 50119683 Common - hypothetical protein ECA0738 9 None None None 50122870 Common - putative zinc-binding dehydrogenase ECA3950 186 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 50123067 Common glgP glycogen phosphorylase ECA4147 145 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 50119637 Common ispB octaprenyl diphosphate synthase ECA0689 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 50121071 Common - GntR-family transcriptional regulator ECA2143 116 COG1802 GntR, Transcriptional regulators Transcription 50122492 Common rpfA hybrid sensory histidine kinase BarA ECA3571 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 50121735 Pathogen - hypothetical protein ECA2811 1 None None None 50120079 Common cyoD cytochrome o ubiquinol oxidase subunit IV ECA1140 58 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 50120281 Common kdpA potassium-transporting ATPase subunit A ECA1342 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 50122422 Common - hypothetical protein ECA3501 49 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 50123369 Common hmsS putative hemin storage protein ECA4451 3 None None None 50121022 Pathogen hrpB type III secretion protein ECA2094 2 None None None 50122598 Pathogen - hypothetical protein ECA3677 3 None None None 50120895 Common - putative hexuronate transporter ECA1967 171 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50122760 Pathogen - putative matrix protein ECA3839 1 None None None 50122962 Common - putative DNA-binding protein ECA4042 49 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 50119046 Common glyS glycyl-tRNA synthetase subunit beta ECA0085 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 50120525 Common - hypothetical protein ECA1591 30 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 50122742 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase ECA3820 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 50122462 Common cysC adenylylsulfate kinase ECA3541 144 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 50120841 Common - MarR-family transcriptional regulator ECA1911 43 COG1846 MarR, Transcriptional regulators Transcription 50119013 Common gdhA glutamate dehydrogenase ECA0051 172 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 50122337 Pathogen - hypothetical protein ECA3413 1 None None None 50122632 Common - conserved hypothetical phage-related protein ECA3711 30 COG3081 COG3081, Nucleoid-associated protein General function prediction only 50121657 Common - hypothetical protein ECA2733 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 50121693 Common glnP glutamine ABC transporter permease protein ECA2769 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50122201 Common lepB lsignal peptidase I ECA3279 181 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 50119115 Common waaX putative beta1,4-galactosyltransferase ECA0154 9 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 50122915 Common aroE shikimate 5-dehydrogenase ECA3995 217 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 50121949 Common nuoC bifunctional NADH:ubiquinone oxidoreductase subunit C/D ECA3026 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 50121567 Common - putative MFS family transporter protein ECA2643 65 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 50123014 Common hofQ predicted fimbrial transporter ECA4094 142 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 50121900 Common - LysR-family transcriptional regulator ECA2976 106 COG0583 LysR, Transcriptional regulator Transcription 50120803 Common - putative glycosyl hydrolase exoenzyme ECA1873 38 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 50121312 Common - hypothetical protein ECA2384 217 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 50122197 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ ECA3275 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 50120275 Common pgm phosphoglucomutase ECA1336 226 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 50121448 Common rimJ ribosomal-protein-S5-alanine N-acetyltransferase ECA2524 99 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 50122236 Common - ATP-dependent RNA helicase HrpB ECA3314 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 50122872 Common - LysR-family transcriptional regulator ECA3952 171 COG0583 LysR, Transcriptional regulator Transcription 50122648 Common - conserved phage-related protein ECA3727 7 None None None 50122427 Common - hypothetical protein ECA3506 29 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 50120232 Common - putative aspartate/glutamate racemase ECA1293 89 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 50122140 Common - hypothetical protein ECA3218 48 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 50119163 Common hemB delta-aminolevulinic acid dehydratase ECA0203 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 50121175 Common - Arac-family transcriptional regulator ECA2247 123 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 50120997 Common - TetR-family transcriptional regulator ECA2069 2 COG1309 AcrR, Transcriptional regulator Transcription 50121221 Common trpH putative phosphoesterase ECA2293 129 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 50121253 Common oppA2 periplasmic oligopeptide-binding protein ECA2325 211 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 50123121 Common wzyE putative enterobacterial common antigen polymerase ECA4201 13 None None None 50122660 Common - putative bacteriophage baseplate protein ECA3738 22 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 50121934 Common pab hypothetical protein ECA3011 123 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 50120590 Pathogen - hypothetical protein ECA1658 1 None None None 50121356 Common - putative glycerophosphoryl diester phosphodiesterase ECA2428 146 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 50122382 Common - hypothetical protein ECA3459 33 COG4938 COG4938, Uncharacterized conserved protein Function unknown 50120836 Common - putative hydrolase ECA1906 101 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 50121966 Common - phosphodiesterase ECA3043 46 COG0622 COG0622, Predicted phosphoesterase General function prediction only 50120264 Common nagA N-acetylglucosamine-6-phosphate deacetylase ECA1325 120 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 50121403 Common eda keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ECA2478 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 50121353 Common kdgR pectin degradation repressor ECA2425 123 COG1414 IclR, Transcriptional regulator Transcription 50120848 Common - hypothetical protein ECA1918 47 COG1556 COG1556, Uncharacterized conserved protein Function unknown 50121886 Common - ABC transporter permease protein ECA2962 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121666 Common rsuA 16S rRNA pseudouridylate synthase A ECA2742 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 50122958 Common rpsL 30S ribosomal protein S12 ECA4038 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 50123240 Common ugpE glycerol-3-phosphate transporter membrane protein ECA4320 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 50119176 Common tuf elongation factor Tu ECA0216 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 50122593 Common - hypothetical protein ECA3672 28 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 50121342 Common - putative ABC transporter ATP-binding protein ECA2414 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 50122342 Common - hypothetical protein ECA3418 7 None None None 50121171 Common dat diaminobutyrate--2-oxoglutarate aminotransferase ECA2243 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 50122374 Pathogen - hypothetical protein ECA3451 2 None None None 50122300 Common - putative bacteriocin immunity protein ECA3378 3 None None None 50122964 Common pmrA DNA-binding response regulator in two-component regulatory system with BasS ECA4044 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 50123239 Common ugpC glycerol-3-phosphate transporter ATP-binding subunit ECA4319 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 50119724 Common - hypothetical protein ECA0779 8 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 50120800 Common arbF beta-glucoside-specific PTS system components IIABC ECA1870 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 50122450 Common proS prolyl-tRNA synthetase ECA3529 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 50122364 Common - hypothetical protein ECA3441 45 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 50122221 Common sbp sulfate-binding protein ECA3299 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 50120943 Common - hypothetical protein ECA2016 9 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 50119159 Common tatA sec-independent protein translocase ECA0199 45 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 50121686 Common - predicted multidrug efflux system ECA2762 93 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 50120757 Common cobB NAD-dependent deacetylase ECA1827 150 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 50121409 Common znuA high-affinity zinc transporter periplasmic component ECA2484 154 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 50119564 Common - putative phage integrase ECA0614 28 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 50121542 Pathogen - phage lysis protein Y, holin ECA2617 7 None None None 50121851 Common - probable transporter ECA2927 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50121927 Common - putative bifunctional protein, includes [GntR-family transcriptional regulator and aminotransferase] ECA3004 228 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 50120460 Common - ABC transporter ATP-binding protein ECA1525 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 50122318 Pathogen - hypothetical protein ECA3394 1 None None None 50120857 Common - hypothetical protein ECA1927 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 50121020 Pathogen - hypothetical protein ECA2092 1 None None None 50121655 Common - hypothetical protein ECA2731 34 None None None 50122885 Common - ribosome-associated GTPase ECA3965 163 COG1162 COG1162, Predicted GTPases General function prediction only 50120336 Common - LacI-family transcriptional regulator ECA1397 127 COG1609 PurR, Transcriptional regulators Transcription 50119152 Common argC N-acetyl-gamma-glutamyl-phosphate reductase ECA0192 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 50122634 Common - putative phage-related membrane protein ECA3713 9 None None None 50122555 Common - LysR-family transcriptional regulator ECA3634 143 COG0583 LysR, Transcriptional regulator Transcription 50123242 Common ugpB glycerol-3-phosphate transporter periplasmic binding protein ECA4322 98 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50121999 Common - putative fimbrial usher protein ECA3076 39 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 50119601 Common - hypothetical protein ECA0652 102 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 50119280 Common - DnaA initiator-associating protein DiaA ECA0320 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 50121102 Pathogen - hypothetical protein ECA2174 1 None None None 50122363 Common - hypothetical protein ECA3440 19 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 50119032 Common - hypothetical protein ECA0070 51 COG2128 COG2128, Uncharacterized conserved protein Function unknown 50121905 Common - hypothetical protein ECA2981 19 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 50121149 Common - TetR-family transcriptional regulator ECA2223 26 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 50119391 Common rhaB rhamnulokinase ECA0440 157 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 50119792 Common - putative sugar ABC transporter, permease protein ECA0849 165 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 50119322 Common scrY putative sucrose porin ECA0363 26 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 50121380 Common ogt probable methylated DNA--protein-cysteine methyltransferase ECA2454 211 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 50119502 Common - hypothetical protein ECA0553 2 None None None 50119706 Common - putative SAM-dependent methyltransferase ECA0761 29 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 50123320 Common ibpB heat shock chaperone IbpB ECA4402 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 50119498 Common traF putative plasmid transfer protein ECA0549 9 None None None 50123263 Common rpoH RNA polymerase factor sigma-32 ECA4343 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 50123289 Common - hypothetical protein ECA4369 17 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 50121462 Common pyrD dihydroorotate dehydrogenase 2 ECA2538 231 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 50123435 Common atpI F0F1 ATP synthase subunit I ECA4519 14 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 50122183 Common - hypothetical protein ECA3261 10 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 50120619 Common flhD transcriptional activator FlhD ECA1685 27 None None None 50122038 Common - aminotransferase ECA3115 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 50122151 Common sseB enhanced serine sensitivity protein ECA3229 14 None None None 50119741 Common - hypothetical protein ECA0796 2 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 50121289 Common nhaB sodium/proton antiporter ECA2361 30 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 50121752 Common - hypothetical protein ECA2828 73 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 50122697 Common ulaA ascorbate-specific PTS system enzyme IIC ECA3775 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 50121084 Common - ABC transporter, substrate binding protein ECA2156 125 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50120650 Common fliO flagellar protein ECA1717 26 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 50120760 Common - hypothetical protein ECA1830 34 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 50120889 Common cstA carbon starvation protein ECA1961 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 50121884 Common - ABC transporter ATP-binding protein ECA2960 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 50122846 Common - Holliday junction resolvase-like protein ECA3926 179 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 50119587 Common - hypothetical protein ECA0638 12 COG5393 COG5393, Predicted membrane protein Function unknown 50122799 Common rpsT 30S ribosomal protein S20 ECA3878 208 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 50121161 Common - hypothetical protein ECA2234 27 COG3506 COG3506, Uncharacterized conserved protein Function unknown 50121470 Common - hypothetical protein ECA2546 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 50120215 Common - ABC transporter ATP binding component ECA1276 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 50121110 Common - translation-associated GTPase ECA2183 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 50119533 Common - restriction enzyme alpha subunit ECA0584 97 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 50122061 Common sfuB iron(III)-transport system permease protein ECA3138 186 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 50121485 Common - putative iron ABC transporter, ATP-binding protein ECA2561 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 50123259 Common livM leucine/isoleucine/valine transporter permease subunit ECA4339 140 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 50122282 Common ffh signal recognition particle protein ECA3360 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 50121041 Pathogen dspE putative avirulence protein ECA2113 2 None None None 50123430 Common atpA F0F1 ATP synthase subunit alpha ECA4514 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 50122248 Pathogen - hypothetical protein ECA3326 2 None None None 50123407 Common - 3-oxoacyl-(acyl carrier protein) synthase II ECA4491 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50119267 Common rpsI 30S ribosomal protein S9 ECA0307 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 50119554 Common cfa5 coronafacic acid synthetase, ligase component ECA0604 185 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 50119057 Common xylB xylulose kinase ECA0096 182 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 50121070 Common - urea amidolyase ECA2142 230 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 50122868 Common - hypothetical protein ECA3948 2 None None None 50122944 Common rplP 50S ribosomal protein L16 ECA4024 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 50123024 Common hslR heat shock protein ECA4104 96 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 50119427 Common - putative iron transporter ECA0476 79 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50119655 Common evr virulence regulator ECA0708 151 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 50119902 Common - putative restriction enzyme ECA0960 15 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 50121481 Common msbA lipid transporter ATP-binding/permease protein ECA2557 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 50122180 Common purL phosphoribosylformylglycinamidine synthase ECA3258 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 50121992 Common aroC chorismate synthase ECA3069 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 50122725 Common - hypothetical protein ECA3803 43 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 50119690 Common gcvP glycine dehydrogenase ECA0745 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 50121843 Common - hypothetical protein ECA2919 8 None None None 50120750 Common - TetR-family transcriptional regulator ECA1819 100 COG1309 AcrR, Transcriptional regulator Transcription 50122624 Common - conserved hypothetical phage-related protein ECA3703 40 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 50121217 Common - short chain dehydrogenase ECA2289 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50121244 Common - hypothetical protein ECA2316 74 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 50119450 Common wcaJ putative capsular polysaccharide biosynthesis protein ECA0499 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 50122099 Common malG maltose/maltodextrin transport permease protein ECA3177 166 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 50119670 Common - hypothetical protein ECA0725 45 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 50120091 Common ppiD peptidyl-prolyl cis-trans isomerase (rotamase D) ECA1152 158 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 50119861 Common - probable transport protein ECA0919 157 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 50121062 Common - ABC transporter, substrate binding protein ECA2134 36 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 50120767 Pathogen - hypothetical protein ECA1837 1 None None None 50119583 Common - LysR-family transcriptional regulator ECA0634 147 COG0583 LysR, Transcriptional regulator Transcription 50120083 Common ampG muropeptide transporter ECA1144 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50122694 Common - LacI-family transcriptional regulator ECA3772 124 COG1609 PurR, Transcriptional regulators Transcription 50118966 Common mioC flavodoxin ECA0001 72 COG0716 FldA, Flavodoxins Energy production and conversion 50119527 Common - hypothetical protein ECA0578 22 None None None 50119969 Common glnD PII uridylyl-transferase ECA1029 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 50123357 Common recF recombination protein F ECA4439 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 50121150 Common - putative transporter ECA2224 72 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 50119301 Common - PTS system, EIIa component ECA0342 122 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 50120386 Common - hypothetical protein ECA1447 14 None None None 50122680 Common - ABC transporter substrate-binding protein ECA3758 176 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 50123398 Common - hypothetical protein ECA4482 3 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 50119166 Common fre FMN reductase ECA0206 107 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 50120255 Common corC magnesium and cobalt efflux protein corc ECA1316 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 50121144 Common srfB putative virulence effector protein ECA2218 14 COG4457 SrfB, Uncharacterized protein conserved in bacteria, putative virulence factor Function unknown 50122640 Common - putative phage-related protein ECA3719 23 COG4373 COG4373, Mu-like prophage FluMu protein gp28 General function prediction only 50120774 Common hmuU hemin transport system permease protein ECA1844 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 50121413 Common - PTS system, cellobiose-specific IIc component ECA2488 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 50119597 Common - hypothetical protein ECA0648 12 None None None 50120273 Common - hypothetical protein ECA1334 170 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 50120720 Common pyrC dihydroorotase ECA1787 86 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 50120656 Common fliI flagellum-specific ATP synthase ECA1723 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 50122819 Common - NTPase ECA3898 35 COG1986 COG1986, Uncharacterized conserved protein Function unknown 50120581 Pathogen - hypothetical protein ECA1649 1 None None None 50119510 Common - hypothetical protein ECA0561 21 None None None 50120610 Common chpA toxin ChpA ECA1676 40 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 50121794 Pathogen - hypothetical protein ECA2870 1 None None None 50120901 Common sapF peptide transport system ATP-binding protein ECA1973 249 COG4167 SapF, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 50122821 Common slt lytic murein transglycosylase ECA3900 170 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 50120666 Common vioA nucleotide sugar transaminase ECA1733 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 50120002 Common - hypothetical protein ECA1062 12 None None None 50120136 Common - 2Fe-2S ferredoxin YfaE ECA1197 62 COG0633 Fdx, Ferredoxin Energy production and conversion 50122026 Common outJ general secretion pathway protein J ECA3103 26 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 50119699 Common rafA alpha-galactosidase ECA0754 45 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 50119837 Common cysZ putative sulfate transport protein CysZ ECA0895 49 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 50121496 Common citE citrate lyase beta chain ECA2572 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 50121558 Pathogen - hypothetical protein ECA2633 1 None None None 50122105 Common nupC1 nucleoside permease ECA3183 69 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 50123275 Common dcrB hypothetical protein ECA4355 10 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 50119207 Common - putative cystine-binding periplasmic protein ECA0247 186 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 50123220 Common tonB TonB protein ECA4300 42 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 161501886 Common tkrA 2-hydroxyacid dehydrogenase ECA0078 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 50121499 Common - putative fumarylacetoacetate hydrolase ECA2575 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 50120163 Common - hypothetical protein ECA1224 85 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 50122706 Common - hypothetical protein ECA3784 48 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 50121872 Common nifN nitrogenase iron-molybdenum cofactor biosynthesis protein ECA2948 48 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 50120968 Common - serine/threonine dehydratase ECA2040 198 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 50119448 Common phnN ribose 1,5-bisphosphokinase ECA0497 135 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 50121033 Common - type III secretion protein ECA2105 4 None None None 50121714 Common bglX periplasmic beta-glucosidase ECA2790 122 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 50123174 Common - putative iron(III) ABC transporter ATP-binding protein ECA4254 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 50123308 Common dppF dipeptide transporter ATP-binding subunit ECA4390 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 50119689 Common gcvH glycine cleavage system protein H ECA0744 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 50123427 Common atpC F0F1 ATP synthase subunit epsilon ECA4511 180 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 50119972 Common tsf elongation factor Ts ECA1032 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 50119255 Common - putative ABC transporter ATP-binding protein YrbF ECA0295 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 50120393 Common - hypothetical protein ECA1454 32 COG1359 COG1359, Uncharacterized conserved protein Function unknown 50123044 Common kdgT 2-keto-3-deoxygluconate permease ECA4124 27 None None None 50120298 Common sdhA succinate dehydrogenase flavoprotein subunit ECA1359 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 50119262 Common degS serine endoprotease ECA0302 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 50122212 Common - hypothetical protein ECA3290 41 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 50123198 Common - Rhs-family protein ECA4278 72 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 50122413 Common - putative amino acid ABC transporter, ATP-binding protein ECA3492 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 50120200 Common gcvR glycine cleavage system transcriptional repressor ECA1261 32 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 50123379 Common - electron transport protein ECA4462 151 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 50120563 Common - AraC-family transcriptional regulator ECA1629 59 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 50123313 Common maeN Na(+)-malate symporter ECA4395 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 50120816 Common ccmE cytochrome c-type biogenesis protein CcmE ECA1886 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 50121614 Common - putative glutathione S-transferase ECA2690 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50122399 Common mtnK methylthioribose kinase ECA3476 29 COG4857 COG4857, Predicted kinase General function prediction only 50123050 Common - alkaline phosphatase ECA4130 85 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 50122615 Common - hypothetical protein ECA3694 6 None None None 50122784 Common - LysR-family transcriptional regulator ECA3863 116 COG0583 LysR, Transcriptional regulator Transcription 50120224 Common - hypothetical protein ECA1285 33 None None None 50119608 Common - hypothetical protein ECA0660 46 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 50123168 Common - ABC transporter permease protein ECA4248 183 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 50122115 Common - putative protease ECA3193 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 50123342 Common - putative nucleoside hydrolase protein ECA4424 86 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 50119762 Common uxuB putative D-mannonate oxidoreductase ECA0819 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 50123087 Common glpQ glycerophosphodiester phosphodiesterase ECA4167 116 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 50123135 Common rep ATP-dependent DNA helicase Rep ECA4215 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 50120324 Common - hypothetical protein ECA1385 48 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 50120341 Common - predicted hydrolase ECA1402 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 50120914 Common - hypothetical protein ECA1987 42 COG3768 COG3768, Predicted membrane protein Function unknown 50120809 Common nrfE heme lyase subunit NrfE ECA1879 133 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 50121607 Common - hypothetical protein ECA2683 57 COG2985 COG2985, Predicted permease General function prediction only 50119504 Common - hypothetical protein ECA0555 21 None None None 50119350 Common - putative activator or transporter protein of haemolysin-like protein ECA0391 53 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 50120144 Common - hypothetical protein ECA1205 64 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 50122530 Common - hypothetical protein ECA3609 77 COG3189 COG3189, Uncharacterized conserved protein Function unknown 50121524 Common - bacteriophage late gene control protein D ECA2600 37 COG3500 COG3500, Phage protein D General function prediction only 50123271 Common - hypothetical protein ECA4351 14 COG3714 COG3714, Predicted membrane protein Function unknown 50121064 Common - hypothetical protein ECA2136 7 None None None 50122077 Common lpxH UDP-2,3-diacylglucosamine hydrolase ECA3155 73 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 50119333 Common nrdG anaerobic ribonucleotide reductase-activating protein ECA0374 65 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 50123297 Common ggt gamma-glutamyltranspeptidase ECA4379 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 50123155 Common - ABC transporter ATP-binding protein ECA4235 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 50120186 Common hyfA hydrogenase-4 component A ECA1247 135 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 50120209 Common - putative biopolymer transport protein ECA1270 133 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 50120820 Common ccmH2 cytochrome C-type biogenesis protein ECA1890 40 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 50122683 Common - hypothetical protein ECA3761 60 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 50119306 Common sufI repressor protein for FtsI ECA0347 83 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 50119245 Common - hypothetical protein ECA0285 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 50122812 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I ECA3891 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 50122103 Common dld D-lactate dehydrogenase ECA3181 45 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 50123215 Pathogen - hypothetical protein ECA4295 3 None None None 50122790 Common - putative transcriptional regulator ECA3869 89 COG2378 COG2378, Predicted transcriptional regulator Transcription 50121534 Common - phage baseplate assembly protein J ECA2610 37 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 50121867 Pathogen nifW nitrogenase stabilizing/protective protein ECA2943 1 None None None 50122219 Common - sulfate ABC transporter permease protein ECA3297 222 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 50119780 Common - hypothetical protein ECA0837 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 50119144 Common - putative carboxymethylenebutenolidase ECA0184 119 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 50123114 Common - probable amino-acid ABC transporter permease protein ECA4194 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 50119386 Common mgtB Magnesium transport ATPase ECA0435 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 50121841 Pathogen - hypothetical protein ECA2917 1 None None None 50121848 Common - putative lipoprotein ECA2924 3 None None None 50120996 Common - putative permease ECA2068 122 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 50122294 Common - hypothetical protein ECA3372 26 COG5637 COG5637, Predicted integral membrane protein Function unknown 50122571 Common - putative DNA-binding protein ECA3650 85 COG1396 HipB, Predicted transcriptional regulators Transcription 50119088 Common - hypothetical protein ECA0127 60 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 50119644 Common - hypothetical protein ECA0696 98 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 50120799 Common arbG beta-glucoside operon antiterminator ECA1869 29 COG3711 BglG, Transcriptional antiterminator Transcription 50122984 Common crp cAMP-regulatory protein ECA4064 168 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 50120171 Common hypD hydrogenase isoenzyme formation protein ECA1232 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 50121469 Common - hypothetical protein ECA2545 63 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 50120373 Common - putative glycosyl transferase ECA1434 140 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 50121387 Common - hypothetical protein ECA2461 81 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 50123391 Common pstA phosphate transporter permease subunit ECA4475 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 50119921 Common tas putative aldo/keto reductase-family protein ECA0981 193 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 50121393 Pathogen - hypothetical protein ECA2467 1 None None None 50119886 Pathogen - hypothetical protein ECA0944 2 COG3710 CadC, DNA-binding winged-HTH domains Transcription 50119053 Common sodA superoxide dismutase ECA0092 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 50119672 Common deoC deoxyribose-phosphate aldolase ECA0727 137 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 50119927 Common lgt prolipoprotein diacylglyceryl transferase ECA0987 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 50119038 Common - hypothetical protein ECA0077 121 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 50120601 Common - hypothetical protein ECA1669 17 COG5529 COG5529, Pyocin large subunit General function prediction only 50121956 Common - aminotransferase AlaT ECA3033 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 50121858 Common - putative transcriptional regulator ECA2934 138 COG1733 COG1733, Predicted transcriptional regulators Transcription 50120792 Common sufD cysteine desulfurase activator complex subunit SufD ECA1862 172 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 50121862 Common nifA nif-specific regulatory protein ECA2938 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 50120363 Common rfbH CDP-4-keto-6-deoxy-D-glucose-3-dehydratase ECA1424 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 50121940 Common nuoM NADH dehydrogenase subunit M ECA3017 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 50122778 Common surA peptidyl-prolyl cis-trans isomerase SurA ECA3857 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 50122939 Common rplE 50S ribosomal protein L5 ECA4019 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 50120798 Pathogen - hypothetical protein ECA1868 1 None None None 50121003 Common - LysR-family transcriptional regulator ECA2075 184 COG0583 LysR, Transcriptional regulator Transcription 50119364 Common - putative permease ECA0406 102 COG0795 COG0795, Predicted permeases General function prediction only 50122073 Common - hypothetical protein ECA3150 29 COG2501 COG2501, Uncharacterized conserved protein Function unknown 50120316 Common - hypothetical protein ECA1377 6 None None None 50121547 Common - capsid scaffolding protein O ECA2622 22 None None None 50118993 Common typA GTP-binding regulatory protein ECA0030 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 50123388 Common - putative DNA-binding protein ECA4472 114 COG1396 HipB, Predicted transcriptional regulators Transcription 50122256 Common speD S-adenosylmethionine decarboxylase ECA3334 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 50121822 Common - putative plasmid mobilization protein ECA2898 34 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 50120504 Common - putative glutathione S-transferase YghU ECA1570 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50119668 Common - putative sterol transferase ECA0723 34 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 50120246 Common holA DNA polymerase III subunit delta ECA1307 66 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 50121640 Common - putative glutathione S transferase ECA2716 93 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 50121836 Common - putative plasmid-related protein ECA2912 3 None None None 50119632 Common argR arginine repressor ECA0684 76 COG1438 ArgR, Arginine repressor Transcription 50122995 Common - ABC transporter permease protein ECA4075 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 50121278 Common - probable transport protein ECA2350 137 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 50121976 Common cvpA colicin V production protein ECA3053 82 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 50119351 Pathogen - hypothetical protein ECA0394 3 None None None 50119441 Common phnG putative phosphonate metabolism protein ECA0490 31 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 50122773 Common polB DNA polymerase II ECA3852 65 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 50120290 Common - putative allophanate hydrolase subunit 1 ECA1351 102 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 50120737 Common - predicted metallodependent hydrolase ECA1804 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 50120122 Pathogen - hypothetical protein ECA1183 1 None None None 50120398 Common - putative sugar ABC transporter, periplasmic protein ECA1459 116 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 50121988 Common - hypothetical protein ECA3065 17 None None None 50122328 Pathogen - hypothetical protein ECA3404 2 COG4337 COG4337, Uncharacterized protein conserved in bacteria Function unknown 50123421 Common - putative acyltransferase ECA4505 47 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 50121236 Common - putative phage-related protein ECA2308 11 COG3617 COG3617, Prophage antirepressor Transcription 50121271 Common msrB methionine sulfoxide reductase B ECA2343 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 50122543 Common rnr exoribonuclease R ECA3622 203 COG0557 VacB, Exoribonuclease R Transcription 50120148 Common - probable short chain dehydrogenase ECA1209 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 50123004 Common occP octopine permease ATP-binding protein P ECA4084 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 50121898 Common - MutT-like protein ECA2974 58 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 50121321 Common yfeB chelated iron transport system membrane protein ECA2393 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism