Streptococcus agalactiae NEM316, complete genome NC_004368 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 25010211 Common - hypothetical protein gbs0136 229 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 25011027 Pathogen - hypothetical protein gbs0974 1 None None None 25010689 Common - hypothetical protein gbs0629 7 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 25010441 Common - hypothetical protein gbs0367 4 None None None 25011549 Common - hypothetical protein gbs1507 148 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 25011555 Common - hypothetical protein gbs1513 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 25011020 Common - hypothetical protein gbs0967 14 None None None 25010448 Pathogen - hypothetical protein gbs0375 1 None None None 25010805 Common - hypothetical protein gbs0750 7 COG3689 COG3689, Predicted membrane protein Function unknown 25010177 Common - hypothetical protein gbs0102 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 25010251 Common - hypothetical protein gbs0176 196 COG0073 ARC1, EMAP domain General function prediction only 25012062 Common - hypothetical protein gbs2024 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 25011126 Common - hypothetical protein gbs1075 3 COG5153 CVT17, Putative lipase essential for disintegration of autophagic bodies inside the vacuole Intracellular trafficking and secretion / Lipid metabolism 25011894 Common - hypothetical protein gbs1855 27 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 25011346 Common - hypothetical protein gbs1297 55 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 25010731 Common - D-mannonate oxidoreductase gbs0676 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 25011681 Common - hypothetical protein gbs1641 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 25010585 Common - hypothetical protein gbs0516 3 None None None 25011983 Common - hypothetical protein gbs1945 4 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 25011632 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase gbs1591 89 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 25011483 Common - hypothetical protein gbs1441 52 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 25012123 Common - hypothetical protein gbs2088 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 25011045 Common - hypothetical protein gbs0992 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 25010293 Pathogen - hypothetical protein gbs0218 1 None None None 25010390 Common - hypothetical protein gbs0316 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 25010965 Common - hypothetical protein gbs0911 13 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 25011179 Common - hypothetical protein gbs1128 67 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 25012109 Common - hypothetical protein gbs2071 2 None None None 25010378 Common fmt methionyl-tRNA formyltransferase gbs0304 219 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 25010246 Common - pyrroline-5-carboxylate reductase gbs0171 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 25011153 Common - hypothetical protein gbs1102 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25011073 Common - hypothetical protein gbs1019 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25011749 Common - hypothetical protein gbs1709 43 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 25011236 Common - hypothetical protein gbs1185 104 COG2962 RarD, Predicted permeases General function prediction only 25011637 Common - hypothetical protein gbs1596 7 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 25011714 Common - heat shock protein HtpX gbs1674 181 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 25011536 Common rmlD dTDP-L-rhamnose synthase gbs1494 187 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 25012000 Common - hypothetical protein gbs1962 4 None None None 25011068 Pathogen - hypothetical protein gbs1014 1 None None None 25010979 Common - hypothetical protein gbs0925 6 COG0398 COG0398, Uncharacterized conserved protein Function unknown 25010974 Common - hypothetical protein gbs0920 47 COG0456 RimI, Acetyltransferases General function prediction only 25010866 Common - hypothetical protein gbs0811 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 25011086 Common - bifunctional riboflavin kinase/FMN adenylyltransferase gbs1032 211 COG0196 RibF, FAD synthase Coenzyme metabolism 25011642 Common - hypothetical protein gbs1601 5 None None None 25012054 Common - hypothetical protein gbs2016 32 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 25011952 Common - hypothetical protein gbs1913 10 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 25010922 Common - hypothetical protein gbs0867 15 COG4708 COG4708, Predicted membrane protein Function unknown 25011550 Common - hypothetical protein gbs1508 112 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 25011528 Common - hypothetical protein gbs1486 224 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 25011316 Common - hypothetical protein gbs1267 211 COG0628 PerM, Predicted permease General function prediction only 25012169 Common - hypothetical protein gbs2134 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 25010889 Pathogen - hypothetical protein gbs0834 1 None None None 25011248 Common - hypothetical protein gbs1199 19 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 25011517 Common - hypothetical protein gbs1475 18 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 25010716 Common - hypothetical protein gbs0661 5 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 25010758 Pathogen - hypothetical protein gbs0703 1 None None None 25011182 Pathogen - hypothetical protein gbs1131 1 None None None 25010936 Common atpD F0F1 ATP synthase subunit beta gbs0881 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 25011207 Common - hypothetical protein gbs1156 3 None None None 25010634 Common - hypothetical protein gbs0565 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 25011338 Common - hypothetical protein gbs1289 15 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 25010144 Common rplX 50S ribosomal protein L24 gbs0069 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 25011880 Common - putative L-ascorbate 6-phosphate lactonase gbs1841 26 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 25011593 Pathogen - hypothetical protein gbs1551 1 None None None 25011331 Common - ribonuclease Z gbs1282 116 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 25010751 Pathogen - hypothetical protein gbs0696 1 None None None 25010459 Common - hypothetical protein gbs0386 19 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 25010140 Common rplP 50S ribosomal protein L16 gbs0065 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 25010407 Common - hypothetical protein gbs0333 142 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 25011215 Common - ribose-phosphate pyrophosphokinase gbs1164 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 25011849 Common - hypothetical protein gbs1810 25 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 25011620 Common rplK 50S ribosomal protein L11 gbsp002 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 25011417 Common rplJ 50S ribosomal protein L10 gbs1375 216 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 25010308 Common - hypothetical protein gbs0234 195 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 25010083 Common - hypothetical protein gbs0008 229 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 25011650 Common - hypothetical protein gbs1610 49 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 25011867 Common - hypothetical protein gbs1828 4 None None None 25012159 Common - ornithine carbamoyltransferase gbs2124 234 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 25011475 Common - carbamoyl phosphate synthase small subunit gbs1433 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 25012106 Common - hypothetical protein gbs2068 3 None None None 25010384 Common - hypothetical protein gbs0310 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 25010077 Common dnaN DNA polymerase III subunit beta gbs0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 25010351 Common - hypothetical protein gbs0277 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 25011032 Pathogen - hypothetical protein gbs0979 1 None None None 25011618 Common - hypothetical protein gbs1577 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 25010899 Common - uridine kinase gbs0844 78 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 25011379 Common - hypothetical protein gbs1337 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 25010621 Pathogen - hypothetical protein gbs0552 1 None None None 25011740 Common - hypothetical protein gbs1700 26 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 25011253 Common - hypothetical protein gbs1204 32 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 25011228 Common - hypothetical protein gbs1177 202 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 25010206 Common - hypothetical protein gbs0131 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 25010660 Common - hypothetical protein gbs0595 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 25011195 Pathogen - hypothetical protein gbs1144 2 None None None 25012018 Common - hypothetical protein gbs1980 2 None None None 25011100 Common - hypothetical protein gbs1046 174 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 25010319 Common - hypothetical protein gbs0245 86 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 25010314 Pathogen - hypothetical protein gbs0240 1 None None None 25010348 Common proA gamma-glutamyl phosphate reductase gbs0274 193 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 25011563 Common - hypothetical protein gbs1521 6 None None None 25011671 Common - hypothetical protein gbs1631 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 25011569 Common - hypothetical protein gbs1527 29 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 25011690 Common - hypothetical protein gbs1650 13 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 25011059 Pathogen - hypothetical protein gbs1006 1 None None None 25010872 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase gbs0817 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 25010168 Common - hypothetical protein gbs0093 48 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 25010275 Common cysE hypothetical protein gbs0200 189 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 25010432 Pathogen - hypothetical protein gbs0358 1 None None None 25010330 Common - hypothetical protein gbs0256 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 25011052 Pathogen - hypothetical protein gbs0999 1 None None None 25010983 Common dnaE DNA polymerase III DnaE gbs0929 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 25011007 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein gbs0953 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 25011403 Pathogen - hypothetical protein gbs1361 1 None None None 25011701 Common greA transcription elongation factor GreA gbs1661 201 COG0782 GreA, Transcription elongation factor Transcription 25011799 Common - hypothetical protein gbs1760 211 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 25012035 Common - hypothetical protein gbs1997 118 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 25011763 Common - hypothetical protein gbs1723 138 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 25010669 Common - hypothetical protein gbs0605 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 25011302 Common - purine nucleoside phosphorylase gbs1253 118 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 25012038 Pathogen - CAMP factor gbs2000 2 None None None 25010559 Common - hypothetical protein gbs0489 128 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 25010777 Common - hypothetical protein gbs0722 6 None None None 25012075 Common - hypothetical protein gbs2037 61 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 25011058 Pathogen - hypothetical protein gbs1005 1 None None None 25011708 Common dnaI primosomal protein DnaI gbs1668 42 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 25010960 Common - hypothetical protein gbs0906 6 None None None 25010235 Common - hypothetical protein gbs0160 79 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 25011976 Common - hypothetical protein gbs1938 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 25011510 Common - hypothetical protein gbs1468 80 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 25010105 Common - hypothetical protein gbs0030 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 25011283 Common neuD hypothetical protein gbs1234 70 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 25011410 Pathogen - hypothetical protein gbs1368 1 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 25011698 Common - hypothetical protein gbs1658 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25010346 Common - hypothetical protein gbs0272 43 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 25010552 Common - hypothetical protein gbs0481 4 COG4707 COG4707, Uncharacterized protein conserved in bacteria Function unknown 25010095 Common - hypothetical protein gbs0020 24 None None None 25011192 Pathogen - hypothetical protein gbs1141 1 None None None 25011684 Common scpA segregation and condensation protein A gbs1644 146 COG1354 COG1354, Uncharacterized conserved protein Function unknown 25011251 Common - hypothetical protein gbs1202 35 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 25012155 Common - hypothetical protein gbs2120 96 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 25011261 Common - hypothetical protein gbs1212 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 25011444 Common - hypothetical protein gbs1402 16 COG1846 MarR, Transcriptional regulators Transcription 25010462 Pathogen - hypothetical protein gbs0389 1 None None None 25010884 Common alaS alanyl-tRNA synthetase gbs0829 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010264 Common - hypothetical protein gbs0189 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 25010572 Common - hypothetical protein gbs0502 37 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 25012150 Common recF recombination protein F gbs2115 169 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 25012047 Common - similar to two-component response regulator gbs2009 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25010911 Common - hypothetical protein gbs0856 5 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 25010861 Common - hypothetical protein gbs0806 145 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 25010943 Common pheT phenylalanyl-tRNA synthetase subunit beta gbs0888 247 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 25010400 Common - hypothetical protein gbs0326 171 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 25012166 Common - hypothetical protein gbs2131 11 COG4485 COG4485, Predicted membrane protein Function unknown 25011258 Common - hypothetical protein gbs1209 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 25011492 Common - hypothetical protein gbs1450 129 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 25010397 Common - hypothetical protein gbs0323 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 25011791 Common - hypothetical protein gbs1752 7 None None None 25010386 Common - hypothetical protein gbs0312 229 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 25010827 Common - hypothetical protein gbs0772 102 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 25010579 Common - hypothetical protein gbs0509 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 25011844 Common - hypothetical protein gbs1805 4 COG3942 COG3942, Surface antigen General function prediction only 25011931 Common - hypothetical protein gbs1892 29 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 25011692 Common - hypothetical protein gbs1652 15 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 25011351 Common - hypothetical protein gbs1302 5 None None None 25012104 Common - hypothetical protein gbs2066 2 None None None 25011294 Common cpsD capsular polysaccharide chain length regulator/exporter gbs1244 140 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 25010336 Common - hypothetical protein gbs0262 10 COG3326 COG3326, Predicted membrane protein Function unknown 25010653 Common - flavodoxin gbs0584 63 COG0716 FldA, Flavodoxins Energy production and conversion 25011835 Common - hypothetical protein gbs1796 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 25010855 Common - hypothetical protein gbs0800 66 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 25011783 Common - hypothetical protein gbs1743 19 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 25010471 Common - hypothetical protein gbs0398 5 None None None 25010187 Common gltX glutamyl-tRNA synthetase gbs0112 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 25010561 Common - hypothetical protein gbs0491 6 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 25012020 Common - hypothetical protein gbs1982 4 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 25012093 Common - hypothetical protein gbs2055 77 COG1438 ArgR, Arginine repressor Transcription 25011649 Common - hypothetical protein gbs1609 13 None None None 25010540 Common - hypothetical protein gbs0469 120 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 25011204 Pathogen - hypothetical protein gbs1153 1 None None None 25010649 Common - hypothetical protein gbs0580 163 COG3443 COG3443, Predicted periplasmic or secreted protein General function prediction only 25012131 Common rpsD 30S ribosomal protein S4 gbs2096 249 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 25010415 Common - acetyl-CoA carboxylase subunit alpha gbs0341 175 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 25011706 Common - hypothetical protein gbs1666 137 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 25010354 Common - hypothetical protein gbs0280 134 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 25010199 Common - argininosuccinate lyase gbs0124 237 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 25010744 Common - hypothetical protein gbs0689 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25011950 Common - hypothetical protein gbs1911 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 25011076 Common - hypothetical protein gbs1022 199 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 25011825 Common - hypothetical protein gbs1786 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 25011898 Common purA adenylosuccinate synthetase gbs1859 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 25010128 Common - hypothetical protein gbs0053 190 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 25011280 Common ung uracil-DNA glycosylase gbs1231 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 25011809 Pathogen - hypothetical protein gbs1770 1 None None None 25010138 Common rplV 50S ribosomal protein L22 gbs0063 234 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 25010702 Common cylG hypothetical protein gbs0646 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 25011619 Common rplA 50S ribosomal protein L1 gbsp001 239 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 25011583 Common - hypothetical protein gbs1541 200 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 25010474 Common - hypothetical protein gbs0401 3 None None None 25010951 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 gbs0897 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 25010808 Common - hypothetical protein gbs0753 98 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 25010481 Common - hypothetical protein gbs0408 8 None None None 25010166 Common - hypothetical protein gbs0091 43 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 25011570 Common - hypothetical protein gbs1528 9 None None None 25011438 Common - hypothetical protein gbs1396 34 COG1577 ERG12, Mevalonate kinase Lipid metabolism 25011427 Common thyA thymidylate synthase gbs1385 135 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 25011948 Common - hypothetical protein gbs1909 74 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 25012086 Common - competence damage-inducible protein A gbs2048 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 25010328 Common - hypothetical protein gbs0254 59 COG1695 COG1695, Predicted transcriptional regulators Transcription 25011606 Common - hypothetical protein gbs1565 3 None None None 25011757 Common - 3-hydroxybutyryl-CoA dehydrogenase gbs1717 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 25012009 Pathogen - hypothetical protein gbs1971 1 None None None 25010547 Pathogen - hypothetical protein gbs0476 1 None None None 25011613 Common pyrH uridylate kinase gbs1572 230 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 25011992 Common - hypothetical protein gbs1954 3 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 25010428 Common - hypothetical protein gbs0354 57 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 25011920 Common - hypothetical protein gbs1881 32 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 25011455 Common - hypothetical protein gbs1413 5 COG4835 COG4835, Uncharacterized protein conserved in bacteria Function unknown 25010659 Common - hypothetical protein gbs0594 4 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 25011398 Common - hypothetical protein gbs1356 7 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 25011924 Common - hypothetical protein gbs1885 11 None None None 25011384 Common - hypothetical protein gbs1342 48 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 25011963 Pathogen - hypothetical protein gbs1925 1 None None None 25010916 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase gbs0861 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 25011040 Common - hypothetical protein gbs0987 6 None None None 25010490 Common infB translation initiation factor IF-2 gbs0417 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 25010288 Pathogen - hypothetical protein gbs0213 2 None None None 25010365 Common - hypothetical protein gbs0291 16 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 25012090 Common mutL DNA mismatch repair protein gbs2052 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 25010642 Common - hypothetical protein gbs0573 18 None None None 25011472 Common - hypothetical protein gbs1430 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 25011174 Pathogen - hypothetical protein gbs1123 1 None None None 25011097 Common - hypothetical protein gbs1043 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 25011113 Common - hypothetical protein gbs1062 7 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 25011105 Common - similar to two-component response regulator LytR gbs1051 180 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 25010204 Common - hypothetical protein gbs0129 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 25011531 Common - hypothetical protein gbs1489 2 None None None 25010512 Common - hypothetical protein gbs0439 88 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 25010724 Common - hypothetical protein gbs0669 60 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 25010711 Pathogen cylK hypothetical protein gbs0655 1 None None None 25011367 Common - hypothetical protein gbs1325 64 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25010791 Common - hypothetical protein gbs0736 20 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 25010772 Common - hypothetical protein gbs0717 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 25011083 Common - hypothetical protein gbs1029 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 25010892 Common - ribonucleotide-diphosphate reductase subunit alpha gbs0837 216 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 25010524 Common - hypothetical protein gbs0451 30 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 25010815 Common - hypothetical protein gbs0760 3 None None None 25010631 Common - hypothetical protein gbs0562 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 25010112 Common - hypothetical protein gbs0037 9 COG5578 COG5578, Predicted integral membrane protein Function unknown 25010394 Common - fructose-6-phosphate aldolase gbs0320 105 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 25010443 Pathogen - hypothetical protein gbs0370 1 None None None 25010842 Common ddl D-alanyl-alanine synthetase A gbs0787 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 25011670 Common - hypothetical protein gbs1630 158 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 25011900 Common - hypothetical protein gbs1861 38 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 25011047 Pathogen - hypothetical protein gbs0994 1 None None None 25011395 Pathogen - hypothetical protein gbs1353 1 None None None 25010426 Common - hypothetical protein gbs0352 135 COG2252 COG2252, Permeases General function prediction only 25011504 Common - hypothetical protein gbs1462 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 25010598 Common - hypothetical protein gbs0529 4 None None None 25010798 Common - hypothetical protein gbs0743 59 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 25010136 Common rplB 50S ribosomal protein L2 gbs0061 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 25011981 Common - hypothetical protein gbs1943 5 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 25011309 Common - hypothetical protein gbs1260 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 25011853 Common rpsL 30S ribosomal protein S12 gbs1814 236 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 25010736 Common - cytoplasmic alpha-amylase gbs0681 100 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 25011729 Common - hypothetical protein gbs1689 130 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 25011165 Common - hypothetical protein gbs1114 104 COG2461 COG2461, Uncharacterized conserved protein Function unknown 25011311 Common - hypothetical protein gbs1262 59 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 25011677 Common - hypothetical protein gbs1637 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 25011775 Common - hypothetical protein gbs1735 51 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 25011879 Common - putative phosphoketolase gbs1840 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 25011095 Common - hypothetical protein gbs1041 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 25011712 Common - hypothetical protein gbs1672 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25011591 Common secG preprotein translocase subunit SecG gbs1549 2 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 25011066 Pathogen - hypothetical protein gbs1012 1 None None None 25010312 Common - hypothetical protein gbs0238 6 None None None 25010557 Common - hypothetical protein gbs0487 2 None None None 25011515 Common - hypothetical protein gbs1473 18 COG3601 COG3601, Predicted membrane protein Function unknown 25012052 Common - hypothetical protein gbs2014 108 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 25010774 Pathogen - hypothetical protein gbs0719 1 None None None 25011226 Common - hypothetical protein gbs1175 137 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 25012069 Common - hypothetical protein gbs2031 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 25011139 Common - hypothetical protein gbs1088 141 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 25010781 Common - hypothetical protein gbs0726 45 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 25011911 Common tsf elongation factor Ts gbs1872 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 25011371 Common - hypothetical protein gbs1329 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 25011644 Common - hypothetical protein gbs1603 28 COG0456 RimI, Acetyltransferases General function prediction only 25011974 Common - hypothetical protein gbs1936 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 25010763 Pathogen - hypothetical protein gbs0708 1 None None None 25010788 Pathogen - hypothetical protein gbs0733 1 None None None 25011318 Common - hypothetical protein gbs1269 35 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 25010636 Common - hypothetical protein gbs0567 13 COG2267 PldB, Lysophospholipase Lipid metabolism 25011735 Common - hypothetical protein gbs1695 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 25011754 Common - pyruvate phosphate dikinase gbs1714 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 25011137 Common - aspartate-semialdehyde dehydrogenase gbs1086 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 25011184 Common - hypothetical protein gbs1133 11 COG3942 COG3942, Surface antigen General function prediction only 25010753 Common - hypothetical protein gbs0698 4 None None None 25010503 Common - hypothetical protein gbs0430 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 25011959 Common - hypothetical protein gbs1920 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 25010614 Common - hypothetical protein gbs0545 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 25011178 Pathogen - hypothetical protein gbs1127 1 None None None 25011423 Common - hypothetical protein gbs1381 14 COG1309 AcrR, Transcriptional regulator Transcription 25010972 Common - hypothetical protein gbs0918 33 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 25011044 Common - hypothetical protein gbs0991 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 25011718 Common - hypothetical protein gbs1678 147 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 25010306 Common - hypothetical protein gbs0232 150 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 25010977 Common - hypothetical protein gbs0923 5 None None None 25010882 Common prsA foldase protein PrsA gbs0827 18 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 25010687 Pathogen - hypothetical protein gbs0627 1 None None None 25011132 Common pyrE orotate phosphoribosyltransferase gbs1081 186 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 25010464 Common - hypothetical protein gbs0391 57 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 25010906 Pathogen - hypothetical protein gbs0851 1 None None None 25011519 Pathogen - hypothetical protein gbs1477 4 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 25012130 Common - hypothetical protein gbs2095 2 None None None 25011285 Common neuB hypothetical protein gbs1236 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 25011419 Common mmuM homocysteine methyltransferase gbs1377 155 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 25010929 Common glgA glycogen synthase gbs0874 139 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 25012013 Common - hypothetical protein gbs1975 35 COG2378 COG2378, Predicted transcriptional regulator Transcription 25010421 Common - hypothetical protein gbs0347 35 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 25011559 Common - hypothetical protein gbs1517 171 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 25011344 Common - hypothetical protein gbs1295 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 25012073 Common - hypothetical protein gbs2035 38 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 25011030 Common - hypothetical protein gbs0977 13 None None None 25011270 Common - hypothetical protein gbs1221 9 COG2932 COG2932, Predicted transcriptional regulator Transcription 25011209 Common - hypothetical protein gbs1158 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 25010487 Common nusA transcription elongation factor NusA gbs0414 223 COG0195 NusA, Transcription elongation factor Transcription 25011299 Common - hypothetical protein gbs1250 2 None None None 25010992 Common rpsT 30S ribosomal protein S20 gbs0938 37 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 25010527 Common nrdI ribonucleotide reductase stimulatory protein gbs0454 39 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 25010248 Pathogen - hypothetical protein gbs0173 1 None None None 25010340 Common - hypothetical protein gbs0266 210 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 25011542 Common - hypothetical protein gbs1500 11 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 25010909 Common - hypothetical protein gbs0854 20 COG4721 COG4721, Predicted membrane protein Function unknown 25011000 Common - hypothetical protein gbs0946 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 25011197 Pathogen - hypothetical protein gbs1146 1 None None None 25011776 Common - hypothetical protein gbs1736 129 COG1609 PurR, Transcriptional regulators Transcription 25011014 Common - hypothetical protein gbs0961 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 25010291 Pathogen - hypothetical protein gbs0216 1 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 25011130 Common pyrB aspartate carbamoyltransferase catalytic subunit gbs1079 236 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 25010450 Common - hypothetical protein gbs0377 6 None None None 25011485 Common - hypothetical protein gbs1443 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 25011899 Common - hypothetical protein gbs1860 14 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 25011683 Common scpB segregation and condensation protein B gbs1643 149 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 25010213 Common - hypothetical protein gbs0138 181 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 25011673 Common - hypothetical protein gbs1633 9 COG4471 COG4471, Uncharacterized protein conserved in bacteria Function unknown 25010098 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase gbs0023 209 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 25011635 Common - hypothetical protein gbs1594 238 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 25011547 Pathogen - hypothetical protein gbs1505 1 None None None 25011304 Common - phosphopentomutase gbs1255 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 25010967 Common - hypothetical protein gbs0913 20 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 25011747 Common - hypothetical protein gbs1707 93 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 25010233 Common - hypothetical protein gbs0158 5 COG4699 COG4699, Uncharacterized protein conserved in bacteria Function unknown 25010181 Common - CTP synthetase gbs0106 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 25011765 Common - hypothetical protein gbs1725 193 COG4989 COG4989, Predicted oxidoreductase General function prediction only 25010667 Common gyrB DNA gyrase subunit B gbs0603 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 25011056 Common - hypothetical protein gbs1003 2 None None None 25011554 Common - hypothetical protein gbs1512 161 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 25010160 Common rplQ 50S ribosomal protein L17 gbs0085 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 25010376 Common - DNA-directed RNA polymerase subunit omega gbs0302 14 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 25012036 Common - hypothetical protein gbs1998 19 None None None 25010320 Common - hypothetical protein gbs0246 114 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 25010434 Common - hypothetical protein gbs0360 12 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 25010402 Common - hypothetical protein gbs0328 167 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 25011412 Common - hypothetical protein gbs1370 134 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 25011602 Common - hypothetical protein gbs1561 66 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 25011520 Common - hypothetical protein gbs1478 8 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 25010277 Common cysS cysteinyl-tRNA synthetase gbs0202 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25011363 Common - hypothetical protein gbs1321 3 None None None 25011461 Common - hypothetical protein gbs1419 10 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 25012133 Common dnaC replicative DNA helicase gbs2098 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 25011818 Common - hypothetical protein gbs1779 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 25011696 Common - hypothetical protein gbs1656 29 COG1254 AcyP, Acylphosphatases Energy production and conversion 25011797 Common - single-strand DNA-binding protein gbs1758 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 25010097 Common - acyl carrier protein gbs0022 171 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 25010874 Common - hypothetical protein gbs0819 83 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 25012026 Common - hypothetical protein gbs1988 10 None None None 25011009 Common - tRNA (uracil-5-)-methyltransferase Gid gbs0955 192 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 25011350 Common - hypothetical protein gbs1301 137 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 25011148 Common - phosphopantothenate--cysteine ligase gbs1097 165 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 25010890 Common - hypothetical protein gbs0835 13 COG3859 COG3859, Predicted membrane protein Function unknown 25011241 Common - hypothetical protein gbs1192 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 25010361 Common pepC hypothetical protein gbs0287 16 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 25011651 Common metG methionyl-tRNA synthetase gbs1611 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010409 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase gbs0335 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 25011034 Common - hypothetical protein gbs0981 5 None None None 25010565 Common - hypothetical protein gbs0495 9 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 25011838 Common - hypothetical protein gbs1799 65 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 25011831 Common - hypothetical protein gbs1792 137 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 25011661 Common serC phosphoserine aminotransferase gbs1621 116 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 25011217 Common - hypothetical protein gbs1166 7 None None None 25010793 Common - hypothetical protein gbs0738 8 None None None 25011473 Common - hypothetical protein gbs1431 124 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 25011039 Common - hypothetical protein gbs0986 23 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 25012114 Pathogen - hypothetical protein gbs2077 1 None None None 25011441 Common - hypothetical protein gbs1399 35 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 25012011 Pathogen - hypothetical protein gbs1973 3 None None None 25010536 Common - hypothetical protein gbs0464 176 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 25011402 Common - hypothetical protein gbs1360 30 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 25010748 Pathogen - hypothetical protein gbs0693 1 None None None 25011915 Common - hypothetical protein gbs1876 101 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 25010270 Common - hypothetical protein gbs0195 215 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 25011629 Common - hypothetical protein gbs1588 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 25011872 Common - D-alanine--D-alanyl carrier protein ligase gbs1833 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 25011071 Common - hypothetical protein gbs1017 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 25011865 Pathogen - hypothetical protein gbs1826 1 None None None 25011998 Common - hypothetical protein gbs1960 17 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 25011070 Pathogen - hypothetical protein gbs1016 1 None None None 25010175 Common - phosphomethylpyrimidine kinase gbs0100 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 25010317 Pathogen - hypothetical protein gbs0243 1 None None None 25010089 Common - hypoxanthine-guanine phosphoribosyltransferase gbs0014 154 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 25011739 Common - hypothetical protein gbs1699 33 COG0789 SoxR, Predicted transcriptional regulators Transcription 25010080 Pathogen - hypothetical protein gbs0005 1 None None None 25010999 Common - hypothetical protein gbs0945 140 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 25011645 Common - hypothetical protein gbs1605 155 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25011565 Common - hypothetical protein gbs1523 9 None None None 25010478 Pathogen - hypothetical protein gbs0405 1 None None None 25011409 Pathogen - hypothetical protein gbs1367 1 None None None 25010868 Common - hypothetical protein gbs0813 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 25012083 Common - hypothetical protein gbs2045 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 25012033 Common - hypothetical protein gbs1995 20 None None None 25010265 Common - hypothetical protein gbs0190 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 25011860 Common - hypothetical protein gbs1821 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 25010619 Common - hypothetical protein gbs0550 11 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 25010352 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase gbs0278 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 25012125 Common - hypothetical protein gbs2090 67 COG2898 COG2898, Uncharacterized conserved protein Function unknown 25012002 Common - recombination factor protein RarA gbs1964 242 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 25010131 Common - hypothetical protein gbs0056 162 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 25011704 Common murC UDP-N-acetylmuramate--L-alanine ligase gbs1664 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 25011827 Common - hypothetical protein gbs1788 213 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 25011003 Common - hypothetical protein gbs0949 23 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 25010746 Common - hypothetical protein gbs0691 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 25010927 Common glgC glucose-1-phosphate adenylyltransferase gbs0872 223 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 25010519 Common - hypothetical protein gbs0446 17 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 25010580 Common - hypothetical protein gbs0510 86 COG1268 BioY, Uncharacterized conserved protein General function prediction only 25011268 Pathogen - hypothetical protein gbs1219 1 None None None 25011996 Common - hypothetical protein gbs1958 93 COG0789 SoxR, Predicted transcriptional regulators Transcription 25010337 Common glpK glycerol kinase gbs0263 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 25012168 Common - hypothetical protein gbs2133 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 25011479 Common - hypothetical protein gbs1437 177 COG0583 LysR, Transcriptional regulator Transcription 25010803 Common - hypothetical protein gbs0748 126 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25011938 Common - hypothetical protein gbs1899 63 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 25011393 Pathogen - hypothetical protein gbs1351 1 None None None 25011211 Common - hypothetical protein gbs1160 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 25011333 Common - hypothetical protein gbs1284 221 COG2262 HflX, GTPases General function prediction only 25010563 Common - hypothetical protein gbs0493 4 None None None 25010202 Common rpmB 50S ribosomal protein L28 gbs0127 88 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 25011275 Common - hypothetical protein gbs1226 2 None None None 25010897 Common - hypothetical protein gbs0842 118 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 25011094 Common - DNA topoisomerase I gbs1040 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 25011163 Common - hypothetical protein gbs1112 127 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 25010554 Common - hypothetical protein gbs0484 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 25010825 Common - hypothetical protein gbs0770 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 25010587 Common - hypothetical protein gbs0518 158 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 25011322 Common rmlA glucose-1-phosphate thymidyltransferase gbs1273 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 25010545 Pathogen - hypothetical protein gbs0474 1 None None None 25010107 Common - N-acetylmannosamine-6-phosphate 2-epimerase gbs0032 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 25012045 Common - hypothetical protein gbs2007 110 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 25011889 Common - putative translaldolase gbs1850 172 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 25011502 Common - hypothetical protein gbs1460 45 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 25010714 Common - hypothetical protein gbs0659 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 25010514 Common - hypothetical protein gbs0441 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 25010499 Common - hypothetical protein gbs0426 124 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 25011737 Common - hypothetical protein gbs1697 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 25011509 Common - putative manganese-dependent inorganic pyrophosphatase gbs1467 54 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 25011499 Common - hypothetical protein gbs1457 4 COG1141 Fer, Ferredoxin Energy production and conversion 25010819 Common - hypothetical protein gbs0764 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 25010326 Common - hypothetical protein gbs0252 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25011490 Common aroB 3-dehydroquinate synthase gbs1448 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 25010962 Common - hypothetical protein gbs0908 23 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 25010612 Common xseB exodeoxyribonuclease VII small subunit gbs0543 77 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 25010501 Common - hypothetical protein gbs0428 2 None None None 25011785 Pathogen - hypothetical protein gbs1745 1 COG4693 PchG, Oxidoreductase (NAD-binding), involved in siderophore biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 25011218 Common - redox-sensing transcriptional repressor Rex gbs1167 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 25011021 Common - hypothetical protein gbs0968 5 None None None 25011453 Common - tRNA CCA-pyrophosphorylase gbs1411 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 25010709 Common cylI hypothetical protein gbs0653 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 25011686 Common - hypothetical protein gbs1646 13 COG0517 COG0517, FOG: CBS domain General function prediction only 25010931 Common atpB F0F1 ATP synthase subunit A gbs0876 200 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 25011837 Common rpsN 30S ribosomal protein S14 gbs1798 203 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 25011141 Common - hypothetical protein gbs1090 69 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 25010958 Common - hypothetical protein gbs0904 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 25011342 Common - hypothetical protein gbs1293 95 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 25011660 Common - hypothetical protein gbs1620 16 None None None 25011296 Common cpsB hypothetical protein gbs1246 37 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 25011349 Common - hypothetical protein gbs1300 29 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 25010722 Common - hypothetical protein gbs0667 15 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 25011365 Pathogen - hypothetical protein gbs1323 1 COG5155 ESP1, Separase, a protease involved in sister chromatid separation Cell division and chromosome partitioning / Posttranslational modification, protein turnover, chaperones 25011382 Pathogen - hypothetical protein gbs1340 1 None None None 25010117 Common - phosphoribosylamine--glycine ligase gbs0042 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 25010185 Common - hypothetical protein gbs0110 59 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 25011878 Common - hypothetical protein gbs1839 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 25010596 Common - hypothetical protein gbs0527 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 25010392 Common - hypothetical protein gbs0318 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 25010110 Common - hypothetical protein gbs0035 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 25010694 Pathogen - hypothetical protein gbs0638 1 None None None 25010209 Common uppP undecaprenyl pyrophosphate phosphatase gbs0134 198 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 25010121 Pathogen - hypothetical protein gbs0046 2 None None None 25010844 Common - hypothetical protein gbs0789 116 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 25010834 Common - hypothetical protein gbs0779 84 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 25010813 Common - prolipoprotein diacylglyceryl transferase gbs0758 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 25010810 Common - hypothetical protein gbs0755 12 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 25012149 Common - hypothetical protein gbs2114 34 COG2501 COG2501, Uncharacterized conserved protein Function unknown 25011902 Pathogen - hypothetical protein gbs1863 1 None None None 25010529 Common - hypothetical protein gbs0456 15 None None None 25010472 Pathogen - hypothetical protein gbs0399 1 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 25011727 Common - hypothetical protein gbs1687 185 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 25011856 Common - hypothetical protein gbs1817 129 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 25010823 Common - riboflavin synthase subunit alpha gbs0768 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 25010914 Common - hydroxyethylthiazole kinase gbs0859 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 25010300 Pathogen - hypothetical protein gbs0225 1 None None None 25010779 Common - hypothetical protein gbs0724 3 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 25012041 Common - hypothetical protein gbs2003 44 COG4420 COG4420, Predicted membrane protein Function unknown 25010645 Common - hypothetical protein gbs0576 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 25011254 Common - hypothetical protein gbs1205 4 COG5547 COG5547, Small integral membrane protein Function unknown 25010863 Common sod manganese-dependent superoxide dismutase gbs0808 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 25012088 Common ruvA Holliday junction DNA helicase motor protein gbs2050 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 25011431 Common - hypothetical protein gbs1389 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 25012147 Common - hypothetical protein gbs2112 184 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 25010601 Common ileS isoleucyl-tRNA synthetase gbs0532 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010223 Common - hypothetical protein gbs0148 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 25010608 Common - hypothetical protein gbs0539 236 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 25011429 Common - hypothetical protein gbs1387 55 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 25010704 Common - hypothetical protein gbs0648 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 25011608 Common - hypothetical protein gbs1567 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 25011470 Common rpsP 30S ribosomal protein S16 gbs1428 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 25012142 Common - hypothetical protein gbs2107 11 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 25011666 Common tdk thymidylate kinase gbs1626 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 25011172 Common - hypothetical protein gbs1121 10 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 25011922 Common def peptide deformylase gbs1883 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 25010363 Common recU Holliday junction-specific endonuclease gbs0289 17 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 25011389 Pathogen - hypothetical protein gbs1347 1 None None None 25010647 Common - hypothetical protein gbs0578 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 25010920 Common - hypothetical protein gbs0865 26 COG1295 Rbn, Predicted membrane protein Function unknown 25011926 Common - hypothetical protein gbs1887 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 25010281 Common - hypothetical protein gbs0206 55 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 25010981 Common - hypothetical protein gbs0927 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25010640 Common - aspartate aminotransferase gbs0571 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 25012060 Common - hypothetical protein gbs2022 5 COG4640 COG4640, Predicted membrane protein Function unknown 25011103 Common - hypothetical protein gbs1049 15 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 25010673 Common - hypothetical protein gbs0609 4 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 25011468 Common - hypothetical protein gbs1426 2 None None None 25012095 Common - hypothetical protein gbs2057 2 None None None 25011111 Pathogen - hypothetical protein gbs1057 1 None None None 25010655 Common - hypothetical protein gbs0586 114 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 25010091 Common pcsB PcsB protein gbs0016 16 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 25011805 Common - hypothetical protein gbs1766 3 None None None 25011721 Common - hypothetical protein gbs1681 17 COG4720 COG4720, Predicted membrane protein Function unknown 25010623 Common - hypothetical protein gbs0554 11 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 25011156 Common - hypothetical protein gbs1105 6 COG3081 COG3081, Nucleoid-associated protein General function prediction only 25012079 Common - anaerobic ribonucleoside triphosphate reductase gbs2041 100 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 25010630 Common - hypothetical protein gbs0561 7 COG1409 Icc, Predicted phosphohydrolases General function prediction only 25010169 Common hrcA heat-inducible transcription repressor gbs0094 144 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 25012071 Common - hypothetical protein gbs2033 58 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 25010520 Common recX recombination regulator RecX gbs0447 33 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 25012059 Common - hypothetical protein gbs2021 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 25011146 Common - hypothetical protein gbs1095 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 25010848 Common - hypothetical protein gbs0793 29 None None None 25011816 Common - hypothetical protein gbs1777 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 25011286 Common cpsM capsular polysaccharide repeat unit transporter gbs1237 48 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 25010315 Common - hypothetical protein gbs0241 13 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 25011766 Common recG hypothetical protein gbs1726 221 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 25010904 Common metK S-adenosylmethionine synthetase gbs0849 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 25010525 Common - hypothetical protein gbs0452 125 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25011002 Common gyrA DNA gyrase subunit A gbs0948 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 25011036 Common - hypothetical protein gbs0983 45 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 25010201 Common - hypothetical protein gbs0126 146 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 25011560 Common - preprotein translocase subunit SecA gbs1518 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 25011917 Common - hypothetical protein gbs1878 82 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 25011863 Common - hypothetical protein gbs1824 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 25011745 Common - hypothetical protein gbs1705 44 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 25012031 Common - hypothetical protein gbs1993 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25010183 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase gbs0108 176 COG0756 Dut, dUTPase Nucleotide transport and metabolism 25012098 Common aspS aspartyl-tRNA synthetase gbs2060 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25012112 Common - hypothetical protein gbs2074 8 None None None 25012119 Common - carbamate kinase gbs2084 67 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 25010859 Common - hypothetical protein gbs0804 128 COG1609 PurR, Transcriptional regulators Transcription 25011552 Common - hypothetical protein gbs1510 66 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 25011055 Common - hypothetical protein gbs1002 6 None None None 25010533 Common - hypothetical protein gbs0460 78 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 25011242 Common - hypothetical protein gbs1193 122 COG2855 COG2855, Predicted membrane protein Function unknown 25011210 Common eutD phosphotransacetylase gbs1159 168 COG0280 Pta, Phosphotransacetylase Energy production and conversion 25010436 Pathogen - hypothetical protein gbs0362 1 None None None 25012101 Common rpmG 50S ribosomal protein L33 gbs2063 82 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 25010234 Common - hypothetical protein gbs0159 207 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 25011128 Common carB carbamoyl phosphate synthase large subunit gbs1077 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 25011965 Common - D-tyrosyl-tRNA deacylase gbs1927 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 25010375 Common gmk guanylate kinase gbs0301 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 25011846 Common - hypothetical protein gbs1807 42 COG0789 SoxR, Predicted transcriptional regulators Transcription 25011522 Common - hypothetical protein gbs1480 193 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 25012135 Common - hypothetical protein gbs2100 72 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 25011224 Common - hypothetical protein gbs1173 139 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 25011413 Pathogen - hypothetical protein gbs1371 1 None None None 25012022 Pathogen - hypothetical protein gbs1984 1 None None None 25010761 Common - hypothetical protein gbs0706 2 None None None 25010665 Common - hypothetical protein gbs0601 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 25010876 Common - hypothetical protein gbs0821 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 25010555 Common - hypothetical protein gbs0485 36 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 25010153 Common secY preprotein translocase subunit SecY gbs0078 217 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 25011752 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A gbs1712 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 25011447 Common - glutamate dehydrogenase gbs1405 168 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 25011858 Common - ribulose-phosphate 3-epimerase gbs1819 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 25011949 Common - hypothetical protein gbs1910 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 25011979 Common - hypothetical protein gbs1941 4 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 25011989 Common - hypothetical protein gbs1951 225 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 25010933 Common atpH F0F1 ATP synthase subunit delta gbs0878 118 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 25010147 Common rpsH 30S ribosomal protein S8 gbs0072 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 25011313 Common - hypothetical protein gbs1264 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 25010431 Common - hypothetical protein gbs0357 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 25012028 Common - hypothetical protein gbs1990 21 COG1695 COG1695, Predicted transcriptional regulators Transcription 25011778 Common - hypothetical protein gbs1738 30 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 25011545 Common - hypothetical protein gbs1503 19 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 25011167 Common - hypothetical protein gbs1116 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 25010949 Common - hypothetical protein gbs0895 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 25010567 Common - asparagine synthetase AsnA gbs0497 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 25011548 Common - hypothetical protein gbs1506 65 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 25010469 Common - hypothetical protein gbs0396 45 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 25010768 Pathogen - hypothetical protein gbs0713 1 None None None 25010492 Common - hypothetical protein gbs0419 41 COG0657 Aes, Esterase/lipase Lipid metabolism 25010982 Common - hypothetical protein gbs0928 109 COG1725 COG1725, Predicted transcriptional regulators Transcription 25010735 Common ccpA catabolite control protein A gbs0680 128 COG1609 PurR, Transcriptional regulators Transcription 25010685 Pathogen - hypothetical protein gbs0622 1 None None None 25010871 Common - hypothetical protein gbs0816 96 COG1846 MarR, Transcriptional regulators Transcription 25010215 Common - hypothetical protein gbs0140 163 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 25012117 Common - hypothetical protein gbs2082 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25010595 Common FtsZ cell division protein FtsZ gbs0526 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 25010713 Pathogen - hypothetical protein gbs0658 1 None None None 25011170 Pathogen - hypothetical protein gbs1119 2 None None None 25011582 Common - hypothetical protein gbs1540 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 25010274 Common - hypothetical protein gbs0199 2 None None None 25012051 Common - hypothetical protein gbs2013 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 25010452 Pathogen - hypothetical protein gbs0379 1 None None None 25011116 Common - hypothetical protein gbs1065 4 None None None 25011478 Common - hypothetical protein gbs1436 134 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 25010349 Common mraW S-adenosyl-methyltransferase MraW gbs0275 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 25011498 Common - hypothetical protein gbs1456 1 None None None 25010938 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase gbs0883 215 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 25011710 Common - hypothetical protein gbs1670 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 25010162 Pathogen - hypothetical protein gbs0087 1 None None None 25011913 Common - hypothetical protein gbs1874 216 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 25011082 Common - hypothetical protein gbs1028 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 25010174 Common truA tRNA pseudouridine synthase A gbs0099 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 25010310 Common - hypothetical protein gbs0236 2 None None None 25012066 Pathogen - hypothetical protein gbs2028 1 None None None 25011064 Common - hypothetical protein gbs1010 4 None None None 25011221 Common arb 6-phospho-beta-glucosidase gbs1170 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 25010191 Common - hypothetical protein gbs0116 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 25010785 Pathogen - hypothetical protein gbs0730 1 None None None 25011190 Pathogen - hypothetical protein gbs1139 1 None None None 25011187 Pathogen - hypothetical protein gbs1136 1 None None None 25011513 Common - hypothetical protein gbs1471 74 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 25011896 Common - hypothetical protein gbs1857 5 None None None 25010249 Common - hypothetical protein gbs0174 1 None None None 25010970 Common ndk nucleoside diphosphate kinase gbs0916 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 25011703 Common - hypothetical protein gbs1663 14 COG0456 RimI, Acetyltransferases General function prediction only 25010975 Common - methionine sulfoxide reductase B gbs0921 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 25011135 Common - hypothetical protein gbs1084 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 25011587 Common - hypothetical protein gbs1545 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25010297 Pathogen - hypothetical protein gbs0222 1 None None None 25011957 Common - galactose-6-phosphate isomerase subunit LacA gbs1918 124 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 25010170 Common - hypothetical protein gbs0095 195 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 25011232 Common - hypothetical protein gbs1181 108 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 25011884 Common - hypothetical protein gbs1845 9 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 25010903 Common - biotin--protein ligase gbs0848 175 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 25010754 Pathogen - hypothetical protein gbs0699 1 None None None 25011574 Common - hypothetical protein gbs1532 38 None None None 25011013 Pathogen - hypothetical protein gbs0959 1 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 25010741 Common - hypothetical protein gbs0686 4 None None None 25010157 Common rpsM 30S ribosomal protein S13 gbs0082 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 25011646 Common - hypothetical protein gbs1606 7 None None None 25011196 Common - hypothetical protein gbs1145 5 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 25011435 Common - isopentenyl pyrophosphate isomerase gbs1393 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 25011927 Common - hypothetical protein gbs1888 39 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 25011388 Pathogen - hypothetical protein gbs1346 1 None None None 25012145 Common - hypothetical protein gbs2110 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 25011440 Common - hypothetical protein gbs1398 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25011653 Common - hypothetical protein gbs1613 14 COG3619 COG3619, Predicted membrane protein Function unknown 25011256 Common - hypothetical protein gbs1207 12 COG2261 COG2261, Predicted membrane protein Function unknown 25011873 Common - hypothetical protein gbs1834 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25011043 Pathogen - hypothetical protein gbs0990 1 None None None 25011624 Common - hypothetical protein gbs1583 1 None None None 25010123 Common - hypothetical protein gbs0048 1 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 25011109 Pathogen - hypothetical protein gbs1055 1 None None None 25010410 Common - 3-oxoacyl-(acyl carrier protein) synthase II gbs0336 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 25010368 Common - S-ribosylhomocysteinase gbs0294 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 25010729 Common - glucuronate isomerase gbs0674 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 25010283 Common - hypothetical protein gbs0208 39 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 25010446 Pathogen - hypothetical protein gbs0373 1 None None None 25010658 Common - unknon gbs0593 2 None None None 25011271 Pathogen - hypothetical protein gbs1222 2 None None None 25011967 Common - 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein gbs1929 133 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 25011340 Common - dipeptidase PepV gbs1291 159 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 25010671 Common - hypothetical protein gbs0607 1 COG5506 COG5506, Uncharacterized conserved protein Function unknown 25011500 Common - hypothetical protein gbs1458 1 None None None 25011487 Common - glutathione reductase gbs1445 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 25012108 Common - hypothetical protein gbs2070 2 None None None 25010603 Common - hypothetical protein gbs0534 18 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 25011907 Common - hypothetical protein gbs1868 100 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 25011662 Common - hypothetical protein gbs1622 55 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 25011725 Common - hypothetical protein gbs1685 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 25010678 Pathogen - hypothetical protein gbs0614 1 None None None 25011162 Common - 4-oxalocrotonate tautomerase gbs1111 13 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 25011118 Pathogen - hypothetical protein gbs1067 2 None None None 25010339 Common glpF hypothetical protein gbs0265 136 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 25010267 Common - hypothetical protein gbs0192 28 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 25010417 Common serS seryl-tRNA synthetase gbs0343 246 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010956 Common - hypothetical protein gbs0902 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 25011903 Common - hypothetical protein gbs1864 21 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 25012004 Pathogen - hypothetical protein gbs1966 1 None None None 25010691 Common - hypothetical protein gbs0631 20 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 25010370 Common - hypothetical protein gbs0296 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25010720 Pathogen - hypothetical protein gbs0665 1 None None None 25010221 Common - hypothetical protein gbs0146 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 25010115 Common - hypothetical protein gbs0040 20 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 25010801 Common - hypothetical protein gbs0746 220 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 25010980 Common - hypothetical protein gbs0926 3 None None None 25011092 Common - hypothetical protein gbs1038 39 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 25011169 Common - hypothetical protein gbs1118 6 None None None 25011507 Common - hypothetical protein gbs1465 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 25010228 Common - hypothetical protein gbs0153 5 None None None 25011180 Pathogen - hypothetical protein gbs1129 1 None None None 25011177 Common - hypothetical protein gbs1126 35 None None None 25011972 Common - hypothetical protein gbs1934 215 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 25010323 Common - hypothetical protein gbs0249 80 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 25011936 Common - hypothetical protein gbs1897 128 COG1846 MarR, Transcriptional regulators Transcription 25010255 Common - hypothetical protein gbs0180 103 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 25011615 Common - hypothetical protein gbs1574 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 25011238 Common - hypothetical protein gbs1187 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 25010817 Common - hypothetical protein gbs0762 111 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 25011985 Common - hypothetical protein gbs1947 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 25011102 Common rbgA ribosomal biogenesis GTPase gbs1048 164 COG1161 COG1161, Predicted GTPases General function prediction only 25010593 Common - hypothetical protein gbs0524 10 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 25011496 Common infC translation initiation factor IF-3 gbs1454 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 25010821 Common - hypothetical protein gbs0766 90 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 25010332 Common glyQ glycyl-tRNA synthetase subunit alpha gbs0258 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 25010589 Common - hypothetical protein gbs0520 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 25010516 Common rnpA ribonuclease P gbs0443 80 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 25010582 Pathogen - hypothetical protein gbs0512 1 None None None 25011262 Common - hypothetical protein gbs1213 194 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 25011562 Common - hypothetical protein gbs1520 5 None None None 25012154 Common - hypothetical protein gbs2119 56 COG1438 ArgR, Arginine repressor Transcription 25010828 Common - hypothetical protein gbs0773 114 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 25010575 Common - hypothetical protein gbs0505 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 25010302 Pathogen - hypothetical protein gbs0228 1 None None None 25011839 Common - O-sialoglycoprotein endopeptidase gbs1800 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 25010109 Common - hypothetical protein gbs0034 139 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 25011355 Common - hypothetical protein gbs1310 33 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 25010990 Common - hypothetical protein gbs0936 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 25011147 Common - hypothetical protein gbs1096 15 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 25012162 Common trpS tryptophanyl-tRNA synthetase II gbs2127 247 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25012044 Common - hypothetical protein gbs2006 14 COG4392 COG4392, Predicted membrane protein Function unknown 25010497 Common - hypothetical protein gbs0424 142 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25012014 Common - hypothetical protein gbs1976 2 None None None 25010102 Common purN phosphoribosylglycinamide formyltransferase gbs0027 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 25011787 Common - hypothetical protein gbs1748 161 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 25011828 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase gbs1789 41 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 25010358 Common - hypothetical protein gbs0284 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 25011088 Common - hypothetical protein gbs1034 21 COG0456 RimI, Acetyltransferases General function prediction only 25010151 Common rpmD 50S ribosomal protein L30 gbs0076 141 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 25011374 Common - hypothetical protein gbs1332 29 COG3711 BglG, Transcriptional antiterminator Transcription 25010377 Common priA primosome assembly protein PriA gbs0303 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 25011466 Common trmD tRNA (guanine-N(1)-)-methyltransferase gbs1424 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 25010944 Common - hypothetical protein gbs0890 32 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 25011449 Common - hypothetical protein gbs1407 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25010125 Common - hypothetical protein gbs0050 110 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 25010705 Common cylA hypothetical protein gbs0649 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25010196 Common - hypothetical protein gbs0121 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25011832 Common - hypothetical protein gbs1793 118 COG0789 SoxR, Predicted transcriptional regulators Transcription 25010506 Common - hypothetical protein gbs0433 14 COG4357 COG4357, Uncharacterized conserved protein Function unknown 25011943 Common yajC preprotein translocase subunit YajC gbs1904 7 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 25011347 Common - hypothetical protein gbs1298 9 None None None 25011327 Common - adenine phosphoribosyltransferase gbs1278 187 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 25010615 Common - hypothetical protein gbs0546 52 COG1438 ArgR, Arginine repressor Transcription 25010260 Common - hypothetical protein gbs0185 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 25011424 Common - GTPase EngB gbs1382 198 COG0218 COG0218, Predicted GTPase General function prediction only 25010997 Common - hypothetical protein gbs0943 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 25011733 Common - hypothetical protein gbs1693 15 COG1309 AcrR, Transcriptional regulator Transcription 25010522 Common - hypothetical protein gbs0449 25 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 25010880 Common - hypothetical protein gbs0825 82 COG0546 Gph, Predicted phosphatases General function prediction only 25011953 Common - hypothetical protein gbs1914 42 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 25011200 Common - hypothetical protein gbs1149 9 None None None 25011792 Common - hypothetical protein gbs1753 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 25011538 Common rpoD RNA polymerase sigma factor RpoD gbs1496 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 25010836 Common - hypothetical protein gbs0781 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 25012085 Common recA recombinase A gbs2047 217 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 25010381 Common - hypothetical protein gbs0307 160 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 25011813 Common - hypothetical protein gbs1774 99 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 25011004 Common - hypothetical protein gbs0950 47 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 25011391 Common - hypothetical protein gbs1349 3 None None None 25010780 Pathogen - hypothetical protein gbs0725 1 None None None 25011821 Pathogen - hypothetical protein gbs1782 1 None None None 25010544 Pathogen - hypothetical protein gbs0473 1 None None None 25010787 Common - hypothetical protein gbs0732 13 None None None 25010852 Common - hypothetical protein gbs0797 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 25011800 Common - hypothetical protein gbs1761 18 COG1476 COG1476, Predicted transcriptional regulators Transcription 25011234 Common folE GTP cyclohydrolase I gbs1183 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 25010343 Pathogen - hypothetical protein gbs0269 1 None None None 25011376 Common - hypothetical protein gbs1334 96 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 25011634 Common - hypothetical protein gbs1593 94 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 25010438 Pathogen - hypothetical protein gbs0364 1 None None None 25012034 Common - hypothetical protein gbs1996 7 COG1694 MazG, Predicted pyrophosphatase General function prediction only 25011578 Common - hypothetical protein gbs1536 2 None None None 25010253 Common - single-strand DNA-binding protein gbs0178 196 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 25010663 Common - hypothetical protein gbs0598 126 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25011580 Common - hypothetical protein gbs1538 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 25011084 Common - hypothetical protein gbs1030 11 COG4476 COG4476, Uncharacterized protein conserved in bacteria Function unknown 25010086 Pathogen - hypothetical protein gbs0011 1 None None None 25011054 Pathogen - hypothetical protein gbs1001 1 None None None 25011307 Common - hypothetical protein gbs1258 32 COG0627 COG0627, Predicted esterase General function prediction only 25011852 Common rpsG 30S ribosomal protein S7 gbs1813 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 25010531 Common - hypothetical protein gbs0458 16 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 25011628 Common - hypothetical protein gbs1587 190 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 25010985 Common - pyruvate kinase gbs0931 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 25012103 Common - hypothetical protein gbs2065 79 COG0640 ArsR, Predicted transcriptional regulators Transcription 25011567 Common - hypothetical protein gbs1525 29 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 25011244 Pathogen - hypothetical protein gbs1195 2 None None None 25011422 Pathogen - hypothetical protein gbs1380 1 None None None 25011415 Pathogen - hypothetical protein gbs1373 1 None None None 25010239 Common - hypothetical protein gbs0164 2 COG4940 ComGF, Competence protein ComGF Intracellular trafficking and secretion 25010718 Common - hypothetical protein gbs0663 249 COG4619 COG4619, ABC-type uncharacterized transport system, ATPase component General function prediction only 25010237 Common - hypothetical protein gbs0162 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 25010840 Common - hypothetical protein gbs0785 183 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 25011585 Common - hypothetical protein gbs1543 78 COG0778 NfnB, Nitroreductase Energy production and conversion 25011695 Common - hypothetical protein gbs1655 208 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 25011089 Common - hypothetical protein gbs1035 27 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 25010232 Common rpoC DNA-directed RNA polymerase subunit beta' gbs0157 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 25010637 Common - hypothetical protein gbs0568 197 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 25012077 Common - hypothetical protein gbs2039 80 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 25010483 Common - hypothetical protein gbs0410 6 None None None 25011300 Common - hypothetical protein gbs1251 98 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 25011018 Common xerS site-specific tyrosine recombinase XerS gbs0965 214 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25011452 Common - hypothetical protein gbs1410 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 25012137 Common - hypothetical protein gbs2102 157 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 25011368 Pathogen - hypothetical protein gbs1326 1 None None None 25010373 Common - hypothetical protein gbs0299 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 25010590 Common - hypothetical protein gbs0521 1 None None None 25011459 Common - hypothetical protein gbs1417 100 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 25011814 Common - hypothetical protein gbs1775 2 None None None 25011961 Common - hypothetical protein gbs1922 13 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 25011158 Common - hypothetical protein gbs1107 238 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 25010085 Common - hypothetical protein gbs0010 10 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 25011075 Common - hypothetical protein gbs1021 165 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 25012132 Common - hypothetical protein gbs2097 12 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 25010625 Common - hypothetical protein gbs0556 21 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 25011823 Common - hypothetical protein gbs1784 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 25011038 Common - hypothetical protein gbs0985 3 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 25011794 Common - hypothetical protein gbs1755 8 COG4858 COG4858, Uncharacterized membrane-bound protein conserved in bacteria Function unknown 25012121 Common - hypothetical protein gbs2086 135 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25011144 Common - hypothetical protein gbs1093 86 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 25010738 Common - hypothetical protein gbs0683 217 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 25011439 Common - hypothetical protein gbs1397 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25012006 Pathogen - hypothetical protein gbs1968 1 None None None 25010356 Common - hypothetical protein gbs0282 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 25011121 Common - hypothetical protein gbs1070 7 COG4499 COG4499, Predicted membrane protein Function unknown 25010677 Common - hypothetical protein gbs0613 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 25011751 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B gbs1711 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 25011250 Common - hypothetical protein gbs1201 19 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 25011892 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase gbs1853 49 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 25010193 Common - hypothetical protein gbs0118 126 COG1609 PurR, Transcriptional regulators Transcription 25010733 Common - hypothetical protein gbs0678 178 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 25011511 Common - hypothetical protein gbs1469 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 25011743 Common - hypothetical protein gbs1703 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 25011464 Common - hypothetical protein gbs1422 15 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 25011861 Common ksgA dimethyladenosine transferase gbs1822 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 25010569 Common - hypothetical protein gbs0499 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 25010963 Common - hypothetical protein gbs0909 106 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 25011876 Common - hypothetical protein gbs1837 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 25010364 Common - hypothetical protein gbs0290 11 COG4474 COG4474, Uncharacterized protein conserved in bacteria Function unknown 25011315 Common - hypothetical protein gbs1266 31 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 25010857 Common - hypothetical protein gbs0802 138 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 25011099 Common - hypothetical protein gbs1045 190 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 25010783 Common - hypothetical protein gbs0728 5 None None None 25010833 Common - hypothetical protein gbs0778 3 None None None 25010995 Common - cytidine deaminase gbs0941 118 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 25011062 Pathogen - hypothetical protein gbs1009 1 None None None 25010172 Common dnaJ Chaperone protein DnaJ gbs0097 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 25011489 Common aroC chorismate synthase gbs1447 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 25010142 Common rpsQ 30S ribosomal protein S17 gbs0067 221 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 25012064 Common - hypothetical protein gbs2026 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 25010628 Common - hypothetical protein gbs0559 2 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 25011166 Common - hypothetical protein gbs1115 69 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 25010208 Common - hypothetical protein gbs0133 6 COG4907 COG4907, Predicted membrane protein Function unknown 25011011 Common - hypothetical protein gbs0957 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 25011383 Common - hypothetical protein gbs1341 77 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 25010389 Common - hypothetical protein gbs0315 67 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 25010632 Common - hypothetical protein gbs0563 138 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 25011133 Common pyrF orotidine 5'-phosphate decarboxylase gbs1082 162 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 25011189 Pathogen - hypothetical protein gbs1138 1 None None None 25010756 Pathogen - hypothetical protein gbs0701 1 None None None 25010865 Common - hypothetical protein gbs0810 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 25010295 Pathogen - hypothetical protein gbs0220 1 None None None 25010560 Common - hypothetical protein gbs0490 114 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 25010743 Common - hypothetical protein gbs0688 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25011480 Common rpmA 50S ribosomal protein L27 gbs1438 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 25011934 Pathogen - hypothetical protein gbs1895 1 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 25011970 Common - hypothetical protein gbs1932 12 None None None 25011203 Common - hypothetical protein gbs1152 9 None None None 25011279 Common - hypothetical protein gbs1230 170 COG0344 COG0344, Predicted membrane protein Function unknown 25010775 Pathogen - hypothetical protein gbs0720 2 None None None 25011848 Common pgk phosphoglycerate kinase gbs1809 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 25011230 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase gbs1179 208 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 25010973 Common - hypothetical protein gbs0919 60 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 25011771 Common secA preprotein translocase subunit SecA gbs1731 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 161486826 Common obgE GTPase ObgE gbs1537 249 COG0536 Obg, Predicted GTPase General function prediction only 25011882 Common - hypothetical protein gbs1843 14 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 25011598 Common - hypothetical protein gbs1556 13 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 25010610 Common - hypothetical protein gbs0541 217 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 25010508 Common - hypothetical protein gbs0435 64 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 25010412 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase gbs0338 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 25010617 Common - hypothetical protein gbs0548 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 25012143 Common - hypothetical protein gbs2108 79 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 25011994 Common prmA ribosomal protein L11 methyltransferase gbs1956 181 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 25011405 Pathogen - hypothetical protein gbs1363 1 None None None 25010146 Common rpsN 30S ribosomal protein S14 gbs0071 192 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 25011772 Common - hypothetical protein gbs1732 50 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 25010878 Common - hypothetical protein gbs0823 13 COG4469 CoiA, Competence protein General function prediction only 25010244 Pathogen - hypothetical protein gbs0169 1 None None None 25012158 Common - hypothetical protein gbs2123 51 COG2153 ElaA, Predicted acyltransferase General function prediction only 25010460 Common - hypothetical protein gbs0387 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 25010809 Common - hypothetical protein gbs0754 189 COG2183 Tex, Transcriptional accessory protein Transcription 25012024 Common - hypothetical protein gbs1986 27 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 25011955 Common - hypothetical protein gbs1916 106 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 25010940 Common - hypothetical protein gbs0885 5 None None None 25012057 Common secE preprotein translocase subunit SecE gbs2019 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 25010217 Common - hypothetical protein gbs0142 142 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 25011335 Pathogen - hypothetical protein gbs1286 1 None None None 25010523 Common - hypothetical protein gbs0450 88 COG2153 ElaA, Predicted acyltransferase General function prediction only 25012016 Pathogen - hypothetical protein gbs1978 1 None None None 25011543 Common - hypothetical protein gbs1501 184 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 25010954 Common - hypothetical protein gbs0900 54 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 25011768 Common alr alanine racemase gbs1728 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 25012087 Common - hypothetical protein gbs2049 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 25010442 Pathogen - hypothetical protein gbs0369 1 None None None 25012115 Common - hypothetical protein gbs2080 4 COG3212 COG3212, Predicted membrane protein Function unknown 25010683 Common - hypothetical protein gbs0619 2 None None None 25010770 Pathogen - hypothetical protein gbs0715 1 None None None 25010925 Common - hypothetical protein gbs0870 144 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 25010079 Common - hypothetical protein gbs0004 26 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 25010494 Common - hypothetical protein gbs0421 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 25010454 Pathogen - hypothetical protein gbs0381 1 None None None 25011069 Pathogen - hypothetical protein gbs1015 1 None None None 25011723 Common - hypothetical protein gbs1683 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 25010113 Common - hypothetical protein gbs0038 232 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 25010698 Common - hypothetical protein gbs0642 29 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 25011426 Common dfrA hypothetical protein gbs1384 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 25011160 Common prfA peptide chain release factor 1 gbs1109 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 25011524 Common - hypothetical protein gbs1482 44 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 25011183 Common - hypothetical protein gbs1132 3 None None None 25011905 Common - hypothetical protein gbs1866 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 25010693 Pathogen - hypothetical protein gbs0636 2 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 25011909 Common ctsR hypothetical protein gbs1870 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 25010419 Common - hypothetical protein gbs0345 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 25010605 Common - hypothetical protein gbs0536 5 COG4703 COG4703, Uncharacterized protein conserved in bacteria Function unknown 25010644 Common - hypothetical protein gbs0575 25 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 25011664 Common - DNA replication intiation control protein YabA gbs1624 15 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 25010766 Pathogen - hypothetical protein gbs0711 1 None None None 25010538 Common - hypothetical protein gbs0467 148 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 25010838 Common tpiA triosephosphate isomerase gbs0783 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 25010894 Common ptsH hypothetical protein gbs0839 92 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 25010134 Common rplD 50S ribosomal protein L4 gbs0059 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 25011572 Common - hypothetical protein gbs1530 3 None None None 25010226 Common - hypothetical protein gbs0151 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 25011888 Common - hypothetical protein gbs1849 123 COG1609 PurR, Transcriptional regulators Transcription 25010155 Common infA translation initiation factor IF-1 gbs0080 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 25010424 Pathogen - hypothetical protein gbs0350 1 None None None 25010476 Pathogen - hypothetical protein gbs0403 1 None None None 25011293 Common cpsE hypothetical protein gbs1243 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 25010304 Common - hypothetical protein gbs0230 6 None None None 25011199 Pathogen - hypothetical protein gbs1148 1 None None None 25010570 Pathogen - hypothetical protein gbs0500 1 None None None 25010814 Common - hypothetical protein gbs0759 7 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 25011527 Common - hypothetical protein gbs1485 75 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 25010280 Common - hypothetical protein gbs0205 27 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 25011929 Common - hypothetical protein gbs1890 66 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 25010901 Common - DNA polymerase III subunits gamma and tau gbs0846 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 25010321 Common - hypothetical protein gbs0247 98 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 25011361 Pathogen - hypothetical protein gbs1318 1 None None None 25011386 Common - hypothetical protein gbs1344 13 COG1396 HipB, Predicted transcriptional regulators Transcription 25010888 Common - hypothetical protein gbs0833 67 COG1476 COG1476, Predicted transcriptional regulators Transcription 25010918 Common - hypothetical protein gbs0863 23 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 25011017 Common - hypothetical protein gbs0964 116 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25011446 Common - peptide deformylase gbs1404 159 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 25011433 Common - hypothetical protein gbs1391 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 25011656 Common - hypothetical protein gbs1616 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 25010867 Common - hypothetical protein gbs0812 35 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 25010591 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gbs0522 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 25010831 Common - hypothetical protein gbs0776 8 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 25011330 Common - hypothetical protein gbs1281 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 25011107 Pathogen - hypothetical protein gbs1053 1 None None None 25010127 Common - hypothetical protein gbs0052 102 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 25010488 Common - hypothetical protein gbs0415 32 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 25012001 Common - hypothetical protein gbs1963 11 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 25010366 Common - hypothetical protein gbs0292 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 25011941 Common - hypothetical protein gbs1902 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 25011842 Common - hypothetical protein gbs1803 11 COG5503 COG5503, Uncharacterized conserved small protein Function unknown 25011212 Common ppnK inorganic polyphosphate/ATP-NAD kinase gbs1161 238 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 25011345 Common - hypothetical protein gbs1296 151 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 25010333 Common - hypothetical protein gbs0259 79 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 25010198 Common - argininosuccinate synthase gbs0123 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 25011041 Common - hypothetical protein gbs0988 57 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 25011247 Common tpx thiol peroxidase gbs1198 118 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 25011760 Common - aminotransferase AlaT gbs1720 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 25011077 Common - hypothetical protein gbs1023 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 25010444 Pathogen - hypothetical protein gbs0371 1 None None None 25011329 Common - hypothetical protein gbs1280 197 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 25010399 Common comFC hypothetical protein gbs0325 56 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 25010707 Pathogen cylE hypothetical protein gbs0651 1 None None None 25011919 Common - hypothetical protein gbs1880 160 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 25011731 Common - hypothetical protein gbs1691 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 25011337 Common - hypothetical protein gbs1288 157 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 25011533 Common - hypothetical protein gbs1491 165 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25011222 Common - hypothetical protein gbs1171 21 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 25010383 Common - hypothetical protein gbs0309 144 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 25011420 Common - hypothetical protein gbs1378 156 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 25010796 Common - hypothetical protein gbs0741 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25011802 Common - hypothetical protein gbs1763 8 None None None 25011175 Pathogen - hypothetical protein gbs1124 1 None None None 25010850 Common - hypothetical protein gbs0795 115 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 25011951 Common - hypothetical protein gbs1912 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 25010542 Common - hypothetical protein gbs0471 8 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 25012152 Common - hypothetical protein gbs2117 1 COG1395 COG1395, Predicted transcriptional regulator Transcription 25011622 Common - hypothetical protein gbs1581 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 25011617 Common - hypothetical protein gbs1576 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 25011648 Common - hypothetical protein gbs1608 17 COG1285 SapB, Uncharacterized membrane protein Function unknown 25010405 Common - 3-oxoacyl-(acyl carrier protein) synthase III gbs0331 219 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 25011987 Common - hypothetical protein gbs1949 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 25011494 Common rplT 50S ribosomal protein L20 gbs1452 213 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 25010518 Common - hypothetical protein gbs0445 62 COG1847 Jag, Predicted RNA-binding protein General function prediction only 25011025 Pathogen - hypothetical protein gbs0972 1 None None None 25012049 Pathogen - hypothetical protein gbs2011 1 None None None 25011264 Common - hypothetical protein gbs1215 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 25010913 Common - phosphomethylpyrimidine kinase gbs0858 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 25010549 Pathogen - hypothetical protein gbs0478 1 None None None 25010577 Common - hypothetical protein gbs0507 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25011353 Common lmb laminin-binding surface protein gbs1307 169 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 25010681 Common - hypothetical protein gbs0617 1 None None None 25010093 Common - aromatic amino acid aminotransferase gbs0018 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 25011789 Common - hypothetical protein gbs1750 103 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 25011123 Pathogen - hypothetical protein gbs1072 1 None None None 25011418 Common - hypothetical protein gbs1376 239 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 25010727 Common - hypothetical protein gbs0672 143 COG2186 FadR, Transcriptional regulators Transcription 25011408 Common - hypothetical protein gbs1366 2 None None None 25011321 Common rmlC dTDP-4-keto-6-deoxyglucose-3,5-epimerase gbs1272 154 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 25011811 Common - hypothetical protein gbs1772 56 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 25010100 Common - amidophosphoribosyltransferase gbs0025 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 25011273 Common - hypothetical protein gbs1224 167 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25011260 Common - hypothetical protein gbs1211 122 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 25010347 Common proB gamma-glutamyl kinase gbs0273 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 25012042 Common - bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein gbs2004 177 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 25012164 Common - hypothetical protein gbs2129 51 COG1284 COG1284, Uncharacterized conserved protein Function unknown 25010104 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase gbs0029 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 25011990 Common - hypothetical protein gbs1952 228 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 25010688 Common - hypothetical protein gbs0628 11 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 25011450 Common - hypothetical protein gbs1408 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25011780 Common - hypothetical protein gbs1740 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25010261 Common - hypothetical protein gbs0186 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 25010946 Common - hypothetical protein gbs0892 21 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 25010290 Common - hypothetical protein gbs0215 8 COG2188 PhnF, Transcriptional regulators Transcription 25010935 Common atpG F0F1 ATP synthase subunit gamma gbs0880 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 25011457 Common - hypothetical protein gbs1415 5 COG4331 COG4331, Predicted membrane protein Function unknown 25010338 Common glpD glycerol-3-phosphate dehydrogenase gbs0264 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 25010546 Common - hypothetical protein gbs0475 31 COG1476 COG1476, Predicted transcriptional regulators Transcription 25011267 Pathogen - hypothetical protein gbs1218 1 None None None 25011474 Common - hypothetical protein gbs1432 229 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 25011932 Common - hypothetical protein gbs1893 70 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 25011866 Pathogen - hypothetical protein gbs1827 1 COG4849 COG4849, Uncharacterized protein conserved in bacteria Function unknown 25010611 Common xseA exodeoxyribonuclease VII large subunit gbs0542 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 25011359 Pathogen - hypothetical protein gbs1315 1 None None None 25011022 Common - hypothetical protein gbs0969 6 None None None 25012094 Common argS arginyl-tRNA synthetase gbs2056 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010672 Common eno phosphopyruvate hydratase gbs0608 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 25010463 Pathogen - hypothetical protein gbs0390 2 None None None 25010530 Common - hypothetical protein gbs0457 19 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 25011274 Common rpsA 30S ribosomal protein S1 gbs1225 227 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 25010345 Common - hypothetical protein gbs0271 3 None None None 25010551 Pathogen - hypothetical protein gbs0480 1 None None None 25012156 Common - hypothetical protein gbs2121 41 COG3382 COG3382, Uncharacterized conserved protein Function unknown 25010511 Common - hypothetical protein gbs0438 101 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 25010571 Common coaD phosphopantetheine adenylyltransferase gbs0501 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 25011626 Common - hypothetical protein gbs1585 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 25010826 Common lysS lysyl-tRNA synthetase gbs0771 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 25010341 Common - hypothetical protein gbs0267 6 COG3711 BglG, Transcriptional antiterminator Transcription 25010263 Common - hypothetical protein gbs0188 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 25012046 Common - hypothetical protein gbs2008 76 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 25010433 Common - hypothetical protein gbs0359 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25011782 Common - hypothetical protein gbs1742 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 25011259 Common - hypothetical protein gbs1210 33 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 25012165 Common - hypothetical protein gbs2130 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 25010129 Common - alcohol dehydrogenase gbs0054 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 25011824 Common - hypothetical protein gbs1785 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 25010278 Common - hypothetical protein gbs0203 38 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 25011456 Pathogen - hypothetical protein gbs1414 1 None None None 25011897 Pathogen - hypothetical protein gbs1858 1 None None None 25011997 Common - hypothetical protein gbs1959 10 COG3153 COG3153, Predicted acetyltransferase General function prediction only 25010875 Common - hypothetical protein gbs0820 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 25011758 Common - hypothetical protein gbs1718 35 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 25010502 Common - similar to two-component response regulator gbs0429 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25012019 Common - hypothetical protein gbs1981 2 None None None 25011029 Pathogen - hypothetical protein gbs0976 1 None None None 25011462 Common - hypothetical protein gbs1420 4 None None None 25010599 Common - hypothetical protein gbs0530 31 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 25010507 Common - hypothetical protein gbs0434 97 COG1268 BioY, Uncharacterized conserved protein General function prediction only 25010578 Common - hypothetical protein gbs0508 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25011942 Common - hypothetical protein gbs1903 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 25010470 Pathogen - hypothetical protein gbs0397 1 None None None 25011469 Common - hypothetical protein gbs1427 21 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 25010266 Common - hypothetical protein gbs0191 50 COG3711 BglG, Transcriptional antiterminator Transcription 25011205 Common - guanosine 5'-monophosphate oxidoreductase gbs1154 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 25010654 Pathogen - hypothetical protein gbs0585 1 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 25010130 Common thrC threonine synthase gbs0055 137 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 25010618 Common - hypothetical protein gbs0549 19 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 25011901 Common - bifunctional glutamate--cysteine ligase/glutathione synthetase gbs1862 96 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 25010745 Common - hypothetical protein gbs0690 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 25011596 Common - formamidopyrimidine-DNA glycosylase gbs1554 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 25010355 Common - hypothetical protein gbs0281 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25010898 Common - hypothetical protein gbs0843 231 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 25012160 Common - hypothetical protein gbs2125 113 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 25010498 Common polA DNA polymerase I gbs0425 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 25011859 Common - ribosome-associated GTPase gbs1820 163 COG1162 COG1162, Predicted GTPases General function prediction only 25010845 Common - hypothetical protein gbs0790 3 COG5522 COG5522, Predicted integral membrane protein Function unknown 25010562 Common valS valyl-tRNA synthetase gbs0492 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010942 Common - hypothetical protein gbs0887 37 COG0456 RimI, Acetyltransferases General function prediction only 25011707 Common engA GTP-binding protein EngA gbs1667 228 COG1160 COG1160, Predicted GTPases General function prediction only 25010414 Common - acetyl-CoA carboxylase subunit beta gbs0340 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 25012021 Common - hypothetical protein gbs1983 2 None None None 25010120 Common - hypothetical protein gbs0045 1 None None None 25011576 Common glnQ glutamine ABC transporter ATP-binding protein gbs1534 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 25011923 Common - hypothetical protein gbs1884 125 COG1609 PurR, Transcriptional regulators Transcription 25010607 Common - hypothetical protein gbs0538 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 25012055 Common nusG transcription antitermination protein NusG gbs2017 215 COG0250 NusG, Transcription antiterminator Transcription 25011801 Common - hypothetical protein gbs1762 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 25011612 Common frr ribosome recycling factor gbs1571 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 25010799 Common - hypothetical protein gbs0744 5 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 25011396 Pathogen - hypothetical protein gbs1354 1 None None None 25012141 Common - hypothetical protein gbs2106 4 None None None 25010887 Pathogen - hypothetical protein gbs0832 1 None None None 25011370 Common - hypothetical protein gbs1328 41 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 25011605 Common - hypothetical protein gbs1564 37 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 25011886 Common - hypothetical protein gbs1847 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 25010651 Common - hypothetical protein gbs0582 82 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 25011432 Common - hypothetical protein gbs1390 115 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 25010480 Pathogen - hypothetical protein gbs0407 1 None None None 25011114 Pathogen - hypothetical protein gbs1063 1 None None None 25011980 Common - hypothetical protein gbs1942 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25011173 Common - hypothetical protein gbs1122 6 None None None 25011529 Common - hypothetical protein gbs1487 190 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 25011870 Common - D-alanine--poly(phosphoribitol) ligase subunit 2 gbs1831 10 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 25010782 Pathogen - hypothetical protein gbs0727 1 None None None 25010285 Common rpsI 30S ribosomal protein S9 gbs0210 246 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 25011841 Common - hypothetical protein gbs1802 181 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 25010420 Common - hypothetical protein gbs0346 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 25010475 Common - hypothetical protein gbs0402 13 None None None 25011323 Common - hypothetical protein gbs1274 55 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 25011636 Common - hypothetical protein gbs1595 36 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 25011854 Common - purine operon repressor gbs1815 96 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 25010952 Common - hypothetical protein gbs0898 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 25011584 Common - hypothetical protein gbs1542 195 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 25010165 Common - hypothetical protein gbs0090 5 None None None 25010325 Common - hypothetical protein gbs0251 157 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 25011098 Common - hypothetical protein gbs1044 155 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 25011297 Common cpsA hypothetical protein gbs1247 61 COG1316 LytR, Transcriptional regulator Transcription 25010584 Common - hypothetical protein gbs0515 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 25011343 Common uvrC excinuclease ABC subunit C gbs1294 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 25012008 Pathogen - hypothetical protein gbs1970 1 None None None 25011715 Common - hypothetical protein gbs1675 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 25010362 Common - hypothetical protein gbs0288 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 25010835 Common - phosphoenolpyruvate carboxylase gbs0780 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 25010224 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gbs0149 205 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 25011665 Common - DNA polymerase III subunit delta' gbs1625 204 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 25011556 Common - hypothetical protein gbs1514 59 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 25011308 Common - hypothetical protein gbs1259 163 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 25011693 Common - hypothetical protein gbs1653 80 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 25011301 Common - hypothetical protein gbs1252 147 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 25011728 Common - hypothetical protein gbs1688 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 25011505 Common - hypothetical protein gbs1463 37 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 25011437 Common - hypothetical protein gbs1395 29 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 25011164 Common - hypothetical protein gbs1113 110 COG0431 COG0431, Predicted flavoprotein General function prediction only 25011678 Common - hypothetical protein gbs1638 160 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 25011106 Common - hypothetical protein gbs1052 104 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 25011235 Common - hypothetical protein gbs1184 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 25012040 Common - hypothetical protein gbs2002 81 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 25010137 Common rpsS 30S ribosomal protein S19 gbs0062 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 25011046 Common - hypothetical protein gbs0993 19 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 25011310 Common - hypothetical protein gbs1261 89 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 25011482 Common rplU 50S ribosomal protein L21 gbs1440 119 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 25010639 Common - bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon gbs0570 146 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 25011366 Common - hypothetical protein gbs1324 57 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 25010395 Common gldA glycerol dehydrogenase gbs0321 147 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 25010387 Common - hypothetical protein gbs0313 79 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 25011381 Common - hypothetical protein gbs1339 4 None None None 25011352 Pathogen - hypothetical protein gbs1306 1 None None None 25011119 Common - hypothetical protein gbs1068 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 25010737 Common - hypothetical protein gbs0682 111 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 25011877 Common - hypothetical protein gbs1838 178 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 25010427 Common - hypothetical protein gbs0353 197 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 25010806 Common - hypothetical protein gbs0751 91 COG0701 COG0701, Predicted permeases General function prediction only 25010695 Pathogen - hypothetical protein gbs0639 1 None None None 25011526 Common - hypothetical protein gbs1484 65 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 25010429 Common - hypothetical protein gbs0355 63 COG1316 LytR, Transcriptional regulator Transcription 25010408 Common - acyl-carrier-protein S-malonyltransferase gbs0334 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 25010937 Common atpC F0F1 ATP synthase subunit epsilon gbs0882 116 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 25010245 Common - hypothetical protein gbs0170 24 None None None 25011317 Common - hypothetical protein gbs1268 27 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 25011015 Common - hypothetical protein gbs0962 17 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 25010586 Common - hypothetical protein gbs0517 9 COG4483 COG4483, Uncharacterized protein conserved in bacteria Function unknown 25010993 Common - pantothenate kinase gbs0939 82 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 25010391 Common - hypothetical protein gbs0317 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 25010294 Common - hypothetical protein gbs0219 40 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 25011717 Common - hypothetical protein gbs1677 84 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 25010143 Common rplN 50S ribosomal protein L14 gbs0068 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 25011977 Common - hypothetical protein gbs1939 7 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 25011484 Common - thiamine biosynthesis protein ThiI gbs1442 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 25011125 Common - hypothetical protein gbs1074 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 25011566 Common - hypothetical protein gbs1524 193 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25010710 Pathogen cylJ hypothetical protein gbs0654 1 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 25011493 Common - hypothetical protein gbs1451 51 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 25011131 Common pyrC dihydroorotase gbs1080 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 25010486 Common - hypothetical protein gbs0413 145 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 25010440 Pathogen - hypothetical protein gbs0366 1 None None None 25010928 Common - hypothetical protein gbs0873 119 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 25010804 Common - hypothetical protein gbs0749 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 25011378 Common - galactose-6-phosphate isomerase subunit LacA gbs1336 121 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 25012089 Common - hypothetical protein gbs2051 61 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 25011558 Common - hypothetical protein gbs1516 3 None None None 25010739 Common thrS threonyl-tRNA synthetase gbs0684 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010885 Common - hypothetical protein gbs0830 48 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 25010771 Common - hypothetical protein gbs0716 19 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 25010118 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit gbs0043 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 25011143 Common - hypothetical protein gbs1092 105 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 25010465 Common - hypothetical protein gbs0392 6 None None None 25011676 Common - hypothetical protein gbs1636 229 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 25010757 Pathogen - hypothetical protein gbs0702 1 None None None 25011518 Common - hypothetical protein gbs1476 20 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 25010730 Common - mannonate dehydratase gbs0675 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 25011001 Common ldh L-lactate dehydrogenase gbs0947 164 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 25012068 Common groES co-chaperonin GroES gbs2030 198 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 25011594 Common - hypothetical protein gbs1552 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25011428 Common - hypothetical protein gbs1386 58 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 25012063 Common - hypothetical protein gbs2025 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 25011249 Common - hypothetical protein gbs1200 15 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25010385 Common - hypothetical protein gbs0311 217 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 25010750 Pathogen - hypothetical protein gbs0695 1 None None None 25011847 Common - hypothetical protein gbs1808 4 COG4129 COG4129, Predicted membrane protein Function unknown 25010686 Common - hypothetical protein gbs0625 41 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 25010307 Common - hypothetical protein gbs0233 85 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 25011541 Common rpsU 30S ribosomal protein S21 gbs1499 95 None None None 25011993 Common - hypothetical protein gbs1955 165 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 25010764 Pathogen - hypothetical protein gbs0709 1 None None None 25010856 Common - hypothetical protein gbs0801 114 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 25011206 Common - hypothetical protein gbs1155 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 25011406 Common - hypothetical protein gbs1364 76 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 25010230 Common - hypothetical protein gbs0155 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 25012027 Common - hypothetical protein gbs1989 4 None None None 25010907 Pathogen - hypothetical protein gbs0852 1 None None None 25011535 Common - hypothetical protein gbs1493 28 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 25012110 Common - hypothetical protein gbs2072 1 None None None 25011067 Pathogen - hypothetical protein gbs1013 1 None None None 25010627 Common - hypothetical protein gbs0558 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 25011237 Common - homoserine kinase gbs1186 122 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 25011774 Common - hypothetical protein gbs1734 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 25010254 Common - hypothetical protein gbs0179 190 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 25011910 Common - hypothetical protein gbs1871 17 COG2426 COG2426, Predicted membrane protein Function unknown 25011586 Common - hypothetical protein gbs1544 129 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 25011339 Common - hypothetical protein gbs1290 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 25011240 Common - hypothetical protein gbs1191 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 25011964 Common - hypothetical protein gbs1926 171 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 25010179 Common tig trigger factor gbs0104 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 25011680 Common - hypothetical protein gbs1640 139 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 25010163 Common - hypothetical protein gbs0088 23 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 25012080 Common - hypothetical protein gbs2042 3 None None None 25010076 Common dnaA chromosomal replication initiation protein gbs0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 25011940 Common - hypothetical protein gbs1901 200 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 25011252 Common - hypothetical protein gbs1203 26 None None None 25011006 Common - hypothetical protein gbs0952 211 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 25010205 Common - hypothetical protein gbs0130 182 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 25010923 Common ligA NAD-dependent DNA ligase LigA gbs0868 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 25011303 Common - hypothetical protein gbs1254 99 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 25010873 Common - hypothetical protein gbs0818 53 COG1814 COG1814, Uncharacterized membrane protein Function unknown 25011142 Common - hypothetical protein gbs1091 11 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 25011159 Common - hypothetical protein gbs1108 232 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 25010313 Common - hypothetical protein gbs0239 8 None None None 25011658 Common - hypothetical protein gbs1618 216 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 25011152 Pathogen - hypothetical protein gbs1101 1 None None None 25011836 Common - hypothetical protein gbs1797 8 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 25012120 Common - ornithine carbamoyltransferase gbs2085 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 25011214 Common - hypothetical protein gbs1163 9 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 25010675 Common aroK shikimate kinase gbs0611 102 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 25011748 Common - hypothetical protein gbs1708 41 COG1161 COG1161, Predicted GTPases General function prediction only 25010350 Common ftsL hypothetical protein gbs0276 5 COG4839 FtsL, Protein required for the initiation of cell division Cell division and chromosome partitioning 25010150 Common rpsE 30S ribosomal protein S5 gbs0075 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 25012139 Common - hypothetical protein gbs2104 150 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 25011229 Common - hypothetical protein gbs1178 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 25010968 Common - hypothetical protein gbs0914 2 None None None 25010622 Common - dihydroorotate dehydrogenase 1A gbs0553 234 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 25011798 Common rpsF 30S ribosomal protein S6 gbs1759 189 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 25011643 Common - hypothetical protein gbs1602 2 COG3760 COG3760, Uncharacterized conserved protein Function unknown 25010335 Common - hypothetical protein gbs0261 17 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 25010299 Pathogen - hypothetical protein gbs0224 1 None None None 25011288 Common CpsIaJ hypothetical protein gbs1238 216 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25011762 Common - hypothetical protein gbs1722 124 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 25010535 Common - hypothetical protein gbs0462 128 COG0789 SoxR, Predicted transcriptional regulators Transcription 25010236 Common - hypothetical protein gbs0161 3 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 25011700 Common - amidase gbs1660 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 25011185 Pathogen - hypothetical protein gbs1134 1 None None None 25012074 Common - hypothetical protein gbs2036 77 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 25011281 Common - hypothetical protein gbs1232 1 None None None 25010081 Common - translation-associated GTPase gbs0006 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 25010082 Common - peptidyl-tRNA hydrolase gbs0007 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 25010456 Pathogen - hypothetical protein gbs0383 1 None None None 25012105 Pathogen - hypothetical protein gbs2067 1 None None None 25011601 Common era GTP-binding protein Era gbs1560 230 COG1159 Era, GTPase General function prediction only 25011057 Pathogen - hypothetical protein gbs1004 1 None None None 25011868 Common - hypothetical protein gbs1829 2 None None None 25012113 Pathogen - hypothetical protein gbs2076 1 None None None 25011051 Pathogen - hypothetical protein gbs0998 1 None None None 25010984 Common pfkA 6-phosphofructokinase gbs0930 155 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 25010094 Common recO DNA repair protein RecO gbs0019 35 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 25011031 Common - hypothetical protein gbs0978 3 None None None 25011691 Common - hypothetical protein gbs1651 4 None None None 25010668 Common - septation ring formation regulator EzrA gbs0604 32 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 25010401 Common - aspartate kinase gbs0327 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 25011050 Common - hypothetical protein gbs0997 6 None None None 25010276 Pathogen - hypothetical protein gbs0201 1 None None None 25010167 Common - hypothetical protein gbs0092 31 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 25010122 Common - adenylosuccinate lyase gbs0047 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 25010837 Common tuf elongation factor Tu gbs0782 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 25011667 Common - hypothetical protein gbs1627 164 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 25010279 Common - hypothetical protein gbs0204 216 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 25012167 Common - hypothetical protein gbs2132 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 25010597 Common - hypothetical protein gbs0528 31 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 25010132 Common rpsJ 30S ribosomal protein S10 gbs0057 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 25011454 Common - hypothetical protein gbs1412 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 25011394 Common - hypothetical protein gbs1352 102 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 25010926 Common - glycogen branching enzyme gbs0871 148 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 25011784 Common - hypothetical protein gbs1744 12 None None None 25011939 Common proS prolyl-tRNA synthetase gbs1900 235 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25011460 Common - hypothetical protein gbs1418 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 25010701 Common cylD hypothetical protein gbs0645 5 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 25010822 Common - hypothetical protein gbs0767 236 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 25010509 Common - hypothetical protein gbs0436 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 25011104 Common - hypothetical protein gbs1050 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 25011467 Common rimM 16S rRNA-processing protein gbs1425 109 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 25011112 Pathogen - hypothetical protein gbs1061 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 25011117 Pathogen - hypothetical protein gbs1066 1 None None None 25012126 Common - hypothetical protein gbs2091 157 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 25011705 Common - hypothetical protein gbs1665 1 None None None 25012082 Common - Holliday junction resolvase-like protein gbs2044 186 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 25010353 Common - hypothetical protein gbs0279 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 25011219 Common radC DNA repair protein RadC gbs1168 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 25010794 Pathogen - hypothetical protein gbs0739 1 None None None 25010847 Common prfC peptide chain release factor 3 gbs0792 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 25010869 Common - hypothetical protein gbs0814 24 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 25010896 Common - hypothetical protein gbs0841 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 25011843 Common - hypothetical protein gbs1804 161 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 25010854 Common - hypothetical protein gbs0799 74 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 25011024 Common - hypothetical protein gbs0971 8 None None None 25011687 Common - hypothetical protein gbs1647 30 COG0622 COG0622, Predicted phosphoesterase General function prediction only 25011149 Common - phosphopantothenoylcysteine decarboxylase gbs1098 235 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 25010939 Pathogen - hypothetical protein gbs0884 1 None None None 25011357 Common - hypothetical protein gbs1313 5 None None None 25010950 Common - hypothetical protein gbs0896 221 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 25010715 Common - hypothetical protein gbs0660 8 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 25010670 Common - hypothetical protein gbs0606 18 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 25011471 Common - hypothetical protein gbs1429 188 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 25011269 Pathogen - hypothetical protein gbs1220 1 None None None 25010700 Pathogen cylX hypothetical protein gbs0644 1 None None None 25010106 Common - hypothetical protein gbs0031 10 None None None 25010553 Common - hypothetical protein gbs0482 5 None None None 25011325 Common - hypothetical protein gbs1276 32 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 25010573 Common - hypothetical protein gbs0503 89 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 25010824 Common - hypothetical protein gbs0769 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 25010182 Common - hypothetical protein gbs0107 57 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 25010684 Common - hypothetical protein gbs0621 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 25010513 Common - hypothetical protein gbs0440 90 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 25011491 Common aroD 3-dehydroquinate dehydratase gbs1449 48 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 25010272 Common rpsO 30S ribosomal protein S15 gbs0197 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 25010222 Common - hypothetical protein gbs0147 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 25011726 Common - hypothetical protein gbs1686 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 25010521 Common - hypothetical protein gbs0448 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 25010812 Common ptsK HPr kinase/phosphorylase gbs0757 76 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 25010818 Common - hypothetical protein gbs0763 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 25011298 Common cpsY hypothetical protein gbs1248 177 COG0583 LysR, Transcriptional regulator Transcription 25010188 Common - hypothetical protein gbs0113 120 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 25010203 Common - hypothetical protein gbs0128 39 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 25011532 Common - hypothetical protein gbs1490 15 COG2456 COG2456, Uncharacterized conserved protein Function unknown 25010257 Common - hypothetical protein gbs0182 35 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 25010124 Common ruvB Holliday junction DNA helicase B gbs0049 225 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 25010959 Common - hypothetical protein gbs0905 6 COG3272 COG3272, Uncharacterized conserved protein Function unknown 25010725 Common - hypothetical protein gbs0670 89 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 25010697 Common - hypothetical protein gbs0641 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 25010989 Common - hypothetical protein gbs0935 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25011808 Common - hypothetical protein gbs1769 136 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 25010633 Common - peptide chain release factor 2 gbs0564 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 25010268 Common ulaA ascorbate-specific PTS system enzyme IIC gbs0193 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 25011947 Common - hypothetical protein gbs1908 41 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 25011589 Common smpB SsrA-binding protein gbs1547 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 25010602 Common - hypothetical protein gbs0533 3 None None None 25010111 Common - hypothetical protein gbs0036 20 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 25010393 Common - hypothetical protein gbs0319 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 25011756 Common - hypothetical protein gbs1716 22 COG0517 COG0517, FOG: CBS domain General function prediction only 25011291 Common cpsG beta-1,4-galactosyltransferase gbs1241 15 COG5017 COG5017, Uncharacterized conserved protein Function unknown 25010921 Common - hypothetical protein gbs0866 8 COG2246 COG2246, Predicted membrane protein Function unknown 25011319 Common - hyaluronate lyase gbs1270 11 None None None 25011755 Common - hypothetical protein gbs1715 110 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 25011790 Common - hypothetical protein gbs1751 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 25011925 Common - hypothetical protein gbs1886 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 25010648 Common - hypothetical protein gbs0579 25 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 25010860 Common - hypothetical protein gbs0805 53 COG0657 Aes, Esterase/lipase Lipid metabolism 25010496 Common - hypothetical protein gbs0423 131 COG2860 COG2860, Predicted membrane protein Function unknown 25011387 Pathogen - hypothetical protein gbs1345 1 None None None 25011982 Common - hypothetical protein gbs1944 32 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 25011276 Common - branched-chain amino acid aminotransferase gbs1227 197 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 25012091 Common - hypothetical protein gbs2053 182 COG1278 CspC, Cold shock proteins Transcription 25010473 Pathogen - hypothetical protein gbs0400 1 None None None 25010282 Common - hypothetical protein gbs0207 4 COG1476 COG1476, Predicted transcriptional regulators Transcription 25011921 Common - hypothetical protein gbs1882 26 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 25011614 Common - hypothetical protein gbs1573 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 25010656 Common rplS 50S ribosomal protein L19 gbs0587 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 25010212 Common - hypothetical protein gbs0137 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 25010915 Common - hypothetical protein gbs0860 194 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 25010219 Common - hypothetical protein gbs0144 191 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 25011208 Common - hypothetical protein gbs1157 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 25011341 Common - hypothetical protein gbs1292 91 COG0778 NfnB, Nitroreductase Energy production and conversion 25010646 Common - hypothetical protein gbs0577 92 COG0391 COG0391, Uncharacterized conserved protein Function unknown 25012096 Common - hypothetical protein gbs2058 79 COG1284 COG1284, Uncharacterized conserved protein Function unknown 25011096 Common - hypothetical protein gbs1042 43 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 25011380 Common - hypothetical protein gbs1338 19 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 25011443 Common - hypothetical protein gbs1401 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25010287 Pathogen - hypothetical protein gbs0212 2 None None None 25011607 Common - hypothetical protein gbs1566 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 25010422 Common - hypothetical protein gbs0348 42 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 25010449 Common - hypothetical protein gbs0376 2 None None None 25011255 Common - hypothetical protein gbs1206 2 None None None 25012148 Common - hypothetical protein gbs2113 91 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 25011503 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase gbs1461 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 25012061 Common - phosphopentomutase gbs2023 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 25010717 Common - hypothetical protein gbs0662 152 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 25011138 Common - hypothetical protein gbs1087 46 None None None 25010883 Common - hypothetical protein gbs0828 8 COG4894 COG4894, Uncharacterized conserved protein Function unknown 25011930 Common - gluconate 5-dehydrogenase gbs1891 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 25010987 Common - D-fructose-6-phosphate amidotransferase gbs0933 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 25010504 Common - hypothetical protein gbs0431 8 COG5523 COG5523, Predicted integral membrane protein Function unknown 25010752 Pathogen - hypothetical protein gbs0697 1 None None None 25010971 Common - GTP-binding protein LepA gbs0917 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 25011753 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C gbs1713 142 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 25010190 Common - hypothetical protein gbs0115 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 25011154 Common - hypothetical protein gbs1103 237 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25011603 Common - hypothetical protein gbs1562 189 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 25010908 Common - hypothetical protein gbs0853 12 COG4732 COG4732, Predicted membrane protein Function unknown 25011171 Common - hypothetical protein gbs1120 98 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 25012111 Common - hypothetical protein gbs2073 86 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25010759 Pathogen - hypothetical protein gbs0704 1 None None None 25011085 Common spxA transcriptional regulator Spx gbs1031 72 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 25011999 Pathogen - hypothetical protein gbs1961 1 None None None 25010242 Common ackA acetate kinase gbs0167 162 COG0282 ackA, Acetate kinase Energy production and conversion 25011912 Common rpsB 30S ribosomal protein S2 gbs1873 221 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 25011372 Common - hypothetical protein gbs1330 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 25011065 Pathogen - hypothetical protein gbs1011 1 None None None 25010305 Common - hypothetical protein gbs0231 129 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 25011414 Common - hypothetical protein gbs1372 7 None None None 25011850 Common - glyceraldehyde-3-phosphate dehydrogenase gbs1811 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 25012053 Common - hypothetical protein gbs2015 28 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 25011630 Common - hypothetical protein gbs1589 175 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 25011975 Common - hypothetical protein gbs1937 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 25011682 Common - hypothetical protein gbs1642 206 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 25010945 Common - hypothetical protein gbs0891 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 25010451 Pathogen - hypothetical protein gbs0378 1 None None None 25010917 Common - hypothetical protein gbs0862 70 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 25010292 Common - hypothetical protein gbs0217 3 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 25011120 Pathogen - hypothetical protein gbs1069 1 None None None 25010789 Common - hypothetical protein gbs0734 3 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 25011486 Common - hypothetical protein gbs1444 1 None None None 25011194 Common - hypothetical protein gbs1143 19 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 25010311 Common - hypothetical protein gbs0237 119 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25011719 Common - hypothetical protein gbs1679 68 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 25010769 Common - hypothetical protein gbs0714 11 None None None 25010247 Common - hypothetical protein gbs0172 81 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 25011777 Common nusB transcription antitermination protein NusB gbs1737 191 COG0781 NusB, Transcription termination factor Transcription 25011893 Common - hypothetical protein gbs1854 39 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 25012153 Common - inositol-5-monophosphate dehydrogenase gbs2118 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 25010458 Pathogen - hypothetical protein gbs0385 1 None None None 25010214 Common - hypothetical protein gbs0139 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 25012023 Common - hypothetical protein gbs1985 4 None None None 25010149 Common rplR 50S ribosomal protein L18 gbs0074 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 25011713 Common - hypothetical protein gbs1673 7 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 25011960 Common - hypothetical protein gbs1921 4 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 25012012 Pathogen - hypothetical protein gbs1974 2 None None None 25010430 Common - hypothetical protein gbs0356 1 None None None 25011689 Common - glutamate racemase gbs1649 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 25010600 Common - hypothetical protein gbs0531 43 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 25010491 Common rbfA ribosome-binding factor A gbs0418 147 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 25011080 Common - hypothetical protein gbs1026 227 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 25011767 Common - hypothetical protein gbs1727 9 COG3942 COG3942, Surface antigen General function prediction only 25010773 Common - hypothetical protein gbs0718 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 25011521 Common - hypothetical protein gbs1479 2 None None None 25010178 Common - hypothetical protein gbs0103 96 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 25011796 Common rpsR 30S ribosomal protein S18 gbs1757 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 25011364 Common - hypothetical protein gbs1322 2 None None None 25011008 Common - hypothetical protein gbs0954 137 COG2188 PhnF, Transcriptional regulators Transcription 25011411 Pathogen - hypothetical protein gbs1369 1 None None None 25010762 Common - hypothetical protein gbs0707 6 None None None 25011404 Common - hypothetical protein gbs1362 3 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 25010467 Common - hypothetical protein gbs0394 3 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 25011945 Common - hypothetical protein gbs1906 202 COG0281 SfcA, Malic enzyme Energy production and conversion 25011883 Common - hypothetical protein gbs1844 171 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 25010891 Common nrdF ribonucleotide-diphosphate reductase subunit beta gbs0836 150 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 25011672 Common - hypothetical protein gbs1632 125 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 25011282 Common neuA CMP-N-acetylneuraminic acid synthetase gbs1233 74 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 25010096 Common - fatty acid/phospholipid synthesis protein gbs0021 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 25010629 Common - hypothetical protein gbs0560 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 25011079 Common - hypothetical protein gbs1025 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 25010139 Common rpsC 30S ribosomal protein S3 gbs0064 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 25011305 Common - ribose-5-phosphate isomerase A gbs1256 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 25011764 Common - hypothetical protein gbs1724 221 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 25012107 Common - hypothetical protein gbs2069 14 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 25010666 Common - hypothetical protein gbs0602 52 COG0546 Gph, Predicted phosphatases General function prediction only 25010159 Common rpoA DNA-directed RNA polymerase subunit alpha gbs0084 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 25012029 Common - hypothetical protein gbs1991 19 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 25012072 Common - hypothetical protein gbs2034 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25011969 Common - hypothetical protein gbs1931 86 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 25010961 Common - coproporphyrinogen III oxidase gbs0907 208 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 25011553 Common - hypothetical protein gbs1511 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 25011679 Common trkA potassium transporter peripheral membrane component gbs1639 158 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 25010435 Pathogen - hypothetical protein gbs0361 1 None None None 25010403 Common - enoyl-CoA hydratase gbs0329 118 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 25012010 Common - hypothetical protein gbs1972 27 COG1476 COG1476, Predicted transcriptional regulators Transcription 25010259 Common - hypothetical protein gbs0184 202 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 25011442 Common - hypothetical protein gbs1400 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25011227 Common - hypothetical protein gbs1176 196 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 25010747 Pathogen - hypothetical protein gbs0692 1 None None None 25011746 Common nadD nicotinic acid mononucleotide adenyltransferase gbs1706 185 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 25012039 Common - topology modulation protein gbs2001 41 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 25011530 Common - hypothetical protein gbs1488 15 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 25010088 Common - hypothetical protein gbs0013 210 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 25011401 Common - hypothetical protein gbs1359 10 COG3942 COG3942, Surface antigen General function prediction only 25011807 Common - hypothetical protein gbs1768 118 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 25010905 Pathogen - hypothetical protein gbs0850 3 None None None 25011332 Common - hypothetical protein gbs1283 3 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 25011871 Common - hypothetical protein gbs1832 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 25010379 Common - hypothetical protein gbs0305 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 25011074 Common - hypothetical protein gbs1020 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25010252 Common - hypothetical protein gbs0177 8 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 25011738 Common - hypothetical protein gbs1698 20 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 25010998 Common - hypothetical protein gbs0944 127 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 25010613 Common - hypothetical protein gbs0544 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 25011916 Pathogen - hypothetical protein gbs1877 1 None None None 25011140 Common - hypothetical protein gbs1089 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 25010661 Common - hypothetical protein gbs0596 17 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 25011436 Common - hypothetical protein gbs1394 14 COG1577 ERG12, Mevalonate kinase Lipid metabolism 25010484 Common - hypothetical protein gbs0411 10 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 25011699 Common - hypothetical protein gbs1659 94 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 25012032 Common - hypothetical protein gbs1994 16 COG1396 HipB, Predicted transcriptional regulators Transcription 25012128 Common - hypothetical protein gbs2093 75 COG1511 COG1511, Predicted membrane protein Function unknown 25010564 Common - hypothetical protein gbs0494 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 25011826 Common - hypothetical protein gbs1787 167 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 25010360 Common nadE NAD synthetase gbs0286 158 COG0171 NadE, NAD synthase Coenzyme metabolism 25011830 Common - hypothetical protein gbs1791 102 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 25012003 Pathogen - hypothetical protein gbs1965 1 None None None 25011516 Common - hypothetical protein gbs1474 4 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 25011819 Common - hypothetical protein gbs1780 8 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 25011659 Common - hypothetical protein gbs1619 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 25012058 Common - hypothetical protein gbs2020 205 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 25011216 Common - hypothetical protein gbs1165 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 25012134 Common rplI 50S ribosomal protein L9 gbs2099 208 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 25010792 Pathogen - hypothetical protein gbs0737 1 None None None 25011312 Common - hypothetical protein gbs1263 88 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 25010895 Common ptsI phosphoenolpyruvate:sugar phosphotransferase system enzyme I gbs0840 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 25010485 Common trmB tRNA (guanine-N(7))-methyltransferase gbs0412 175 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 25011320 Common - hypothetical protein gbs1271 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 25010324 Common - hypothetical protein gbs0250 72 COG1309 AcrR, Transcriptional regulator Transcription 25010284 Common rplM 50S ribosomal protein L13 gbs0209 218 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 25011272 Common - hypothetical protein gbs1223 24 COG4823 AbiF, Abortive infection bacteriophage resistance protein Defense mechanisms 25011385 Common - hypothetical protein gbs1343 15 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 25010479 Common - hypothetical protein gbs0406 20 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 25010447 Pathogen - hypothetical protein gbs0374 1 None None None 25010740 Common - hypothetical protein gbs0685 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25010495 Common - hypothetical protein gbs0422 3 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 25011984 Common - hypothetical protein gbs1946 59 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 25011968 Common - hypothetical protein gbs1930 33 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 25011573 Common UvrB excinuclease ABC subunit B gbs1531 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 25012140 Common - hypothetical protein gbs2105 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 25011609 Common - hypothetical protein gbs1568 12 COG4479 COG4479, Uncharacterized protein conserved in bacteria Function unknown 25010679 Common aphA acid phosphatase/phosphotransferase gbs0615 12 COG3700 AphA, Acid phosphatase (class B) General function prediction only 25011033 Pathogen - hypothetical protein gbs0980 1 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 25010912 Common - hypothetical protein gbs0857 45 COG0819 TenA, Putative transcription activator Transcription 25011654 Common - hypothetical protein gbs1614 31 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 25010180 Common - DNA-directed RNA polymerase subunit delta gbs0105 12 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 25010588 Common - hypothetical protein gbs0519 28 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 25010650 Common rpmE2 50S ribosomal protein L31 type B gbs0581 170 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 25010988 Common - hypothetical protein gbs0934 106 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 25011257 Common - hypothetical protein gbs1208 8 COG2261 COG2261, Predicted membrane protein Function unknown 25011063 Pathogen - hypothetical protein gbs0368 1 None None None 25010369 Common - hypothetical protein gbs0295 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 25011736 Common - hypothetical protein gbs1696 31 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 25012146 Common pgsA hypothetical protein gbs2111 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 25010289 Pathogen - hypothetical protein gbs0214 1 None None None 25011669 Common - hypothetical protein gbs1629 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 25011874 Common - hypothetical protein gbs1835 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25011434 Common - hypothetical protein gbs1392 1 None None None 25010703 Common acpC hypothetical protein gbs0647 44 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 25010643 Common - hypothetical protein gbs0574 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 25012100 Common rpmF 50S ribosomal protein L32 gbs2062 55 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 25011697 Common - OxaA-like protein precursor gbs1657 159 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 25011399 Common - hypothetical protein gbs1357 12 COG5340 COG5340, Predicted transcriptional regulator Transcription 25011362 Common - hypothetical protein gbs1320 3 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 25011168 Common - xanthine phosphoribosyltransferase gbs1117 90 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 25010227 Common - hypothetical protein gbs0152 192 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 25010398 Common comFA competence protein ComFA gbs0324 110 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 25011181 Pathogen - hypothetical protein gbs1130 1 None None None 25011176 Pathogen - hypothetical protein gbs1125 1 None None None 25011786 Pathogen - hypothetical protein gbs1746 1 None None None 25010802 Common - hypothetical protein gbs0747 115 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25011093 Common - hypothetical protein gbs1039 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 25010229 Common tyrS tyrosyl-tRNA synthetase gbs0154 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010811 Common - hypothetical protein gbs0756 4 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 25011110 Pathogen - hypothetical protein gbs1056 2 None None None 25011239 Common - hypothetical protein gbs1188 2 None None None 25011937 Common polC DNA polymerase III PolC gbs1898 216 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 25010816 Pathogen - hypothetical protein gbs0761 1 None None None 25010594 Common ftsA similar to cell division protein FtsA gbs0525 177 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 25010423 Common - hypothetical protein gbs0349 113 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25010839 Common - phosphoglyceromutase gbs0784 157 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 25010256 Common - hypothetical protein gbs0181 173 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 25011908 Common - hypothetical protein gbs1869 220 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 25011904 Common hslO Hsp33-like chaperonin gbs1865 134 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 25011290 Pathogen cpsI capsular polysaccharide repeating-unit polymerase gbs1240 1 None None None 25011161 Common - thymidine kinase gbs1110 103 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 25010301 Pathogen - hypothetical protein gbs0226 1 None None None 25011425 Common clpX ATP-dependent protease ATP-binding subunit gbs1383 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 25011663 Common - hypothetical protein gbs1623 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 25010604 Common - hypothetical protein gbs0535 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 25011042 Pathogen - hypothetical protein gbs0989 2 None None None 25010126 Common - hypothetical protein gbs0051 25 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 25011508 Common - hypothetical protein gbs1466 3 None None None 25010728 Common - hypothetical protein gbs0673 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 25010371 Common - hypothetical protein gbs0297 37 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 25010957 Common - hypothetical protein gbs0903 13 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 25010699 Common - hypothetical protein gbs0643 34 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 25011655 Common - hypothetical protein gbs1615 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 25010116 Common - hypothetical protein gbs0041 97 COG1737 RpiR, Transcriptional regulators Transcription 25010690 Common - hypothetical protein gbs0630 22 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 25010416 Common - hypothetical protein gbs0342 1 None None None 25010466 Common - hypothetical protein gbs0393 23 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 25011991 Common - hypothetical protein gbs1953 88 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 25010862 Common holA DNA polymerase III subunit delta gbs0807 38 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 25011150 Common - hypothetical protein gbs1099 12 COG4684 COG4684, Predicted membrane protein Function unknown 25010947 Common trmE tRNA modification GTPase TrmE gbs0893 217 COG0486 ThdF, Predicted GTPase General function prediction only 25011087 Common truB tRNA pseudouridine synthase B gbs1033 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 25011049 Pathogen - hypothetical protein gbs0996 1 None None None 25012043 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gbs2005 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 25012015 Pathogen - hypothetical protein gbs1977 1 None None None 25010103 Common - hypothetical protein gbs0028 4 COG3393 COG3393, Predicted acetyltransferase General function prediction only 25011812 Common - hypothetical protein gbs1773 8 None None None 25011501 Common - peptidase T gbs1459 60 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 25010581 Common - hypothetical protein gbs0511 179 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 25011122 Common - hypothetical protein gbs1071 3 COG5417 COG5417, Uncharacterized small protein Function unknown 25012084 Common spxA transcriptional regulator Spx gbs2046 42 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 25012151 Common - hypothetical protein gbs2116 11 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 25011647 Common - hypothetical protein gbs1607 11 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 25011688 Common - putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein gbs1648 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 25011855 Common - hypothetical protein gbs1816 46 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 25011781 Common - hypothetical protein gbs1741 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 25011448 Common - hypothetical protein gbs1406 3 COG3247 HdeD, Uncharacterized conserved protein Function unknown 25010676 Common - hypothetical protein gbs0612 44 COG1316 LytR, Transcriptional regulator Transcription 25010108 Common - hypothetical protein gbs0033 60 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 25011213 Common - hypothetical protein gbs1162 105 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 25011263 Common - hypothetical protein gbs1214 58 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 25010331 Common - hypothetical protein gbs0257 17 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 25010269 Common - hypothetical protein gbs0194 224 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 25011026 Common - hypothetical protein gbs0973 20 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 25011157 Common glyA serine hydroxymethyltransferase gbs1106 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 25010515 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase gbs0442 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 25012161 Common - carbamate kinase gbs2126 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 25010574 Common - hypothetical protein gbs0504 11 COG4470 COG4470, Uncharacterized protein conserved in bacteria Function unknown 25010991 Common - hypothetical protein gbs0937 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 25011793 Common uvrA excinuclease ABC subunit A gbs1754 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 25010359 Common - nicotinate phosphoribosyltransferase gbs0285 113 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 25012127 Common - hypothetical protein gbs2092 10 COG3759 COG3759, Predicted membrane protein Function unknown 25011005 Common - hypothetical protein gbs0951 13 COG4086 COG4086, Predicted secreted protein Function unknown 25010262 Common - hypothetical protein gbs0187 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 25010849 Common - hypothetical protein gbs0794 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 25010786 Common - hypothetical protein gbs0731 3 None None None 25011820 Common - x-prolyl-dipeptidyl aminopeptidase gbs1781 12 COG2936 COG2936, Predicted acyl esterases General function prediction only 25010853 Common - hypothetical protein gbs0798 81 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 25011623 Common - hypothetical protein gbs1582 178 COG0583 LysR, Transcriptional regulator Transcription 25010820 Common - hypothetical protein gbs0765 6 None None None 25011604 Common - hypothetical protein gbs1563 34 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 25010706 Common cylB hypothetical protein gbs0650 11 None None None 25011946 Common - hypothetical protein gbs1907 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 25011732 Common - hypothetical protein gbs1692 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 25010505 Common tgt queuine tRNA-ribosyltransferase gbs0432 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 25011465 Common - hypothetical protein gbs1423 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 25010616 Common - hypothetical protein gbs0547 224 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 25011201 Pathogen - hypothetical protein gbs1150 1 None None None 25010334 Common glyS glycyl-tRNA synthetase subunit beta gbs0260 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 25011833 Common - DNA polymerase III subunit epsilon gbs1794 38 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 25011326 Common - hypothetical protein gbs1277 20 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 25010186 Common - pyridine nucleotide-disulfide oxidoreductase gbs0111 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 25011592 Common - hypothetical protein gbs1550 97 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 25010195 Common - hypothetical protein gbs0120 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 25011806 Common - ribonuclease HIII gbs1767 34 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 25011416 Common rplL 50S ribosomal protein L7/L12 gbs1374 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 25011627 Common - hypothetical protein gbs1586 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 25012030 Common - hypothetical protein gbs1992 9 None None None 25011035 Pathogen - hypothetical protein gbs0982 1 None None None 25010543 Pathogen - hypothetical protein gbs0472 1 None None None 25010176 Common - hypothetical protein gbs0101 14 COG4720 COG4720, Predicted membrane protein Function unknown 25010318 Pathogen - hypothetical protein gbs0244 2 None None None 25011324 Common - hypothetical protein gbs1275 151 COG0327 COG0327, Uncharacterized conserved protein Function unknown 25011918 Common - hypothetical protein gbs1879 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 25011358 Common - hypothetical protein gbs1314 61 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25011744 Common - hypothetical protein gbs1704 46 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 25010184 Common - DNA repair protein RadA gbs0109 205 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 25010795 Common - hypothetical protein gbs0740 6 None None None 25011225 Common - hypothetical protein gbs1174 156 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 25011019 Common - hypothetical protein gbs0966 171 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 25011668 Common - hypothetical protein gbs1628 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 25012097 Common - hypothetical protein gbs2059 55 COG1284 COG1284, Uncharacterized conserved protein Function unknown 25010964 Common - hypothetical protein gbs0910 8 COG4478 COG4478, Predicted membrane protein Function unknown 25011864 Common - hypothetical protein gbs1825 239 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 25011577 Pathogen - hypothetical protein gbs1535 1 None None None 25010271 Common - hypothetical protein gbs0196 66 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 25011674 Common clpP ATP-dependent Clp protease proteolytic subunit gbs1634 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 25010624 Common - hypothetical protein gbs0555 21 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 25010099 Common - hypothetical protein gbs0024 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 25011804 Common - hypothetical protein gbs1765 8 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 25010087 Common - hypothetical protein gbs0012 11 COG2367 PenP, Beta-lactamase class A Defense mechanisms 25010539 Common - hypothetical protein gbs0468 24 COG1309 AcrR, Transcriptional regulator Transcription 25011711 Common - hypothetical protein gbs1671 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25010996 Common - hypothetical protein gbs0942 83 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 25012025 Common - hypothetical protein gbs1987 10 None None None 25010558 Common - hypothetical protein gbs0488 1 None None None 25011430 Common - hypothetical protein gbs1388 7 None None None 25011817 Common - hypothetical protein gbs1778 97 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 25011127 Pathogen - hypothetical protein gbs1076 1 None None None 25012122 Common - hypothetical protein gbs2087 100 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 25010231 Common rpoB DNA-directed RNA polymerase subunit beta gbs0156 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 25010528 Common - ribonucleotide-diphosphate reductase subunit alpha gbs0455 222 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 25011734 Common - hypothetical protein gbs1694 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 25010374 Common - hypothetical protein gbs0300 7 COG3548 COG3548, Predicted integral membrane protein Function unknown 25010696 Common - hypothetical protein gbs0640 72 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 25012136 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA gbs2101 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 25010609 Common - hypothetical protein gbs0540 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 25010723 Common - D-lactate dehydrogenase gbs0668 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 25012078 Common - hypothetical protein gbs2040 2 None None None 25010635 Common - hypothetical protein gbs0566 71 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 25010133 Common rplC 50S ribosomal protein L3 gbs0058 249 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 25010482 Pathogen - hypothetical protein gbs0409 1 None None None 25010846 Common - hypothetical protein gbs0791 6 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 25010969 Pathogen - hypothetical protein gbs0915 1 None None None 25010877 Common - hypothetical protein gbs0822 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 25011857 Common - hypothetical protein gbs1818 33 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 25011373 Common - hypothetical protein gbs1331 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 25011287 Pathogen cpsL capsular polysaccharide biosynthesis protein gbs1237.1 3 None None None 25011881 Common - hypothetical protein gbs1842 31 COG3711 BglG, Transcriptional antiterminator Transcription 25011284 Common neuC hypothetical protein gbs1235 62 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 25010534 Common - hypothetical protein gbs0461 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 25010664 Common - hypothetical protein gbs0600 15 None None None 25012070 Common - hypothetical protein gbs2032 50 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 25011243 Pathogen - hypothetical protein gbs1194 1 None None None 25010776 Common - hypothetical protein gbs0721 57 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 25012129 Common - hypothetical protein gbs2094 19 COG1309 AcrR, Transcriptional regulator Transcription 25011155 Common - hypothetical protein gbs1104 8 None None None 25010437 Pathogen - hypothetical protein gbs0363 1 None None None 25011551 Common - hypothetical protein gbs1509 128 COG1609 PurR, Transcriptional regulators Transcription 25012037 Common - hypothetical protein gbs1999 148 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 25010090 Common ftsH cell division protein FtsH gbs0015 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 25011306 Common - hypothetical protein gbs1257 3 COG5549 COG5549, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 25010258 Common - hypothetical protein gbs0183 81 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 25010298 Common - hypothetical protein gbs0223 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 25011072 Common - hypothetical protein gbs1018 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 25011277 Common - DNA topoisomerase IV subunit A gbs1228 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 25010510 Common pgi glucose-6-phosphate isomerase gbs0437 192 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 25012017 Common - hypothetical protein gbs1979 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 25011935 Common - hypothetical protein gbs1896 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 25010767 Common - hypothetical protein gbs0712 6 None None None 25011334 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase gbs1285 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 25010712 Common - hypothetical protein gbs0657 10 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 25012050 Common leuS leucyl-tRNA synthetase gbs2012 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25012118 Common - hypothetical protein gbs2083 40 COG1288 COG1288, Predicted membrane protein Function unknown 25010749 Pathogen - hypothetical protein gbs0694 1 None None None 25011115 Pathogen - hypothetical protein gbs1064 1 None None None 25010930 Common atpE H+-transporting ATP synthase c chain gbs0875 12 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 25011581 Pathogen - hypothetical protein gbs1539 1 None None None 25010453 Pathogen - hypothetical protein gbs0380 1 None None None 25010216 Common - hypothetical protein gbs0141 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 25011477 Common - hypothetical protein gbs1435 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 25011497 Common cmk cytidylate kinase gbs1455 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 25011652 Common - tellurite resistance protein TehB gbs1612 28 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 25011973 Common - hypothetical protein gbs1935 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 25012056 Pathogen - putative peptidoglycan linked protein gbs2018 2 COG5373 COG5373, Predicted membrane protein Function unknown 25010566 Common - hypothetical protein gbs0496 13 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 25011539 Common dnaG DNA primase gbs1497 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 25011488 Common - hypothetical protein gbs1446 15 COG3679 COG3679, Uncharacterized conserved protein Function unknown 25010158 Common rpsK 30S ribosomal protein S11 gbs0083 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 25011779 Common - elongation factor P gbs1739 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 25011023 Pathogen - hypothetical protein gbs0970 1 None None None 25011314 Common - acetolactate synthase gbs1265 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 25010329 Common - hypothetical protein gbs0255 2 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 25011540 Common mscL large conductance mechanosensitive channel protein MscL gbs1498 143 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 25011546 Common - hypothetical protein gbs1504 109 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 25011514 Common - hypothetical protein gbs1472 77 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 25010461 Common - hypothetical protein gbs0388 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 25011191 Common - hypothetical protein gbs1140 3 None None None 25010682 Common - hypothetical protein gbs0618 7 COG1309 AcrR, Transcriptional regulator Transcription 25011724 Common - hypothetical protein gbs1684 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 25011136 Common - hypothetical protein gbs1085 55 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 25010241 Common - hypothetical protein gbs0166 10 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 25011597 Common - hypothetical protein gbs1555 7 COG1396 HipB, Predicted transcriptional regulators Transcription 25011186 Common - hypothetical protein gbs1135 21 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 25011958 Common - hypothetical protein gbs1919 17 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 25011012 Pathogen - hypothetical protein gbs0958 1 None None None 25010468 Pathogen - hypothetical protein gbs0395 1 None None None 25010924 Common - putative lipid kinase gbs0869 105 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 25010154 Common adk adenylate kinase gbs0079 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 25011887 Pathogen - hypothetical protein gbs1848 2 None None None 25010493 Common - hypothetical protein gbs0420 30 COG3682 COG3682, Predicted transcriptional regulator Transcription 25011233 Common - hypothetical protein gbs1182 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 25012067 Common groEL chaperonin GroEL gbs2029 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 25011890 Common araD L-ribulose-5-phosphate 4-epimerase gbs1851 133 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 25010978 Common - hypothetical protein gbs0924 200 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 25010173 Common - hypothetical protein gbs0098 177 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 25011770 Common - phospho-2-dehydro-3-heoxyheptonate aldolase gbs1730 110 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 25011639 Common - hypothetical protein gbs1598 31 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 25010902 Common - hypothetical protein gbs0847 1 None None None 25010734 Common - hypothetical protein gbs0679 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 25011769 Common acpS 4'-phosphopantetheinyl transferase gbs1729 143 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 25011568 Common - hypothetical protein gbs1526 35 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 25011702 Common - hypothetical protein gbs1662 187 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 25010760 Pathogen - hypothetical protein gbs0705 1 None None None 25010411 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit gbs0337 193 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 25011060 Pathogen - hypothetical protein gbs1007 1 None None None 25010192 Common - hypothetical protein gbs0117 186 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 25011914 Common - hypothetical protein gbs1875 248 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 25010537 Common - hypothetical protein gbs0466 136 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 25011610 Common - methionine sulfoxide reductase A gbs1569 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 25010396 Common cysK hypothetical protein gbs0322 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 25010726 Common - beta-D-glucuronidase gbs0671 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 25010955 Common - hypothetical protein gbs0901 57 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 25010135 Common rplW 50S ribosomal protein L23 gbs0060 188 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 25012081 Common - hypothetical protein gbs2043 15 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 25010919 Common - methionine aminopeptidase gbs0864 241 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 25010225 Common - hypothetical protein gbs0150 7 COG1846 MarR, Transcriptional regulators Transcription 25010425 Common - hypothetical protein gbs0351 18 COG4330 COG4330, Predicted membrane protein Function unknown 25011292 Common cpsF beta-1,4-galactosyltransferase enhancer gbs1242 17 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 25012005 Common - hypothetical protein gbs1967 4 None None None 25010303 Pathogen - hypothetical protein gbs0229 1 None None None 25011523 Common - hypothetical protein gbs1481 16 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 25011198 Common - hypothetical protein gbs1147 22 COG1476 COG1476, Predicted transcriptional regulators Transcription 25010934 Common atpA F0F1 ATP synthase subunit alpha gbs0879 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 25011445 Common - hypothetical protein gbs1403 112 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 25011944 Common - hypothetical protein gbs1905 3 None None None 25010721 Common - hypothetical protein gbs0666 190 COG0583 LysR, Transcriptional regulator Transcription 25010220 Common - hypothetical protein gbs0145 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 25010692 Common - hypothetical protein gbs0632 7 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 25010592 Common murG N-acetylglucosaminyl transferase gbs0523 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 25010114 Common - hypothetical protein gbs0039 119 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 25010418 Common - hypothetical protein gbs0344 13 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 25011906 Common - hypothetical protein gbs1867 39 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 25011369 Common - hypothetical protein gbs1327 10 COG1396 HipB, Predicted transcriptional regulators Transcription 25010606 Common - hypothetical protein gbs0537 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25011506 Common - hypothetical protein gbs1464 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 25010830 Common - hypothetical protein gbs0775 88 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 25010286 Common - hypothetical protein gbs0211 149 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25010164 Common - hypothetical protein gbs0089 8 None None None 25010296 Pathogen - hypothetical protein gbs0221 1 None None None 25010477 Common - hypothetical protein gbs0404 3 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 25010171 Common dnaK molecular chaperone DnaK gbs0096 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 25011986 Common - hypothetical protein gbs1948 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25010641 Common asnC asparaginyl-tRNA synthetase gbs0572 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 25011557 Pathogen - hypothetical protein gbs1515 1 None None None 25011101 Common rnhB ribonuclease HII gbs1047 210 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 25010832 Common - hypothetical protein gbs0777 13 COG1928 PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase Posttranslational modification, protein turnover, chaperones 25010445 Pathogen - hypothetical protein gbs0372 1 None None None 25011834 Common - hypothetical protein gbs1795 2 None None None 25010500 Common - hypothetical protein gbs0427 153 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 25011675 Common upp uracil phosphoribosyltransferase gbs1635 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 25011616 Common - hypothetical protein gbs1575 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 25010367 Common - hypothetical protein gbs0293 3 None None None 25010207 Common - hypothetical protein gbs0132 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25011336 Common - hypothetical protein gbs1287 22 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 25011928 Common - hypothetical protein gbs1889 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 25012144 Common - hypothetical protein gbs2109 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 25010119 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit gbs0044 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 25011722 Common - hypothetical protein gbs1682 155 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 25010657 Common - hypothetical protein gbs0589 6 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 25012092 Common mutS DNA mismatch repair protein gbs2054 205 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 25010322 Common - hypothetical protein gbs0248 6 None None None 25011571 Common - hypothetical protein gbs1529 3 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 25010797 Common - hypothetical protein gbs0742 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 25011803 Common - hypothetical protein gbs1764 205 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 25010910 Common - hypothetical protein gbs0855 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 25010652 Common - adenosine deaminase gbs0583 107 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 25010620 Common - HU like DNA-binding protein gbs0551 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 25010548 Pathogen - hypothetical protein gbs0477 1 None None None 25011954 Common - tagatose 1,6-diphosphate aldolase gbs1915 25 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 25011397 Common - hypothetical protein gbs1355 9 None None None 25011795 Common - hypothetical protein gbs1756 88 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 25011621 Common - hypothetical protein gbs1580 199 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 25010851 Common - hypothetical protein gbs0796 99 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 25011537 Common - hypothetical protein gbs1495 150 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 25010357 Common - hypothetical protein gbs0283 2 None None None 25011822 Common - hypothetical protein gbs1783 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 25011246 Common - hypothetical protein gbs1197 2 None None None 25011048 Common - hypothetical protein gbs0995 11 None None None 25011512 Common - hypothetical protein gbs1470 28 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 25011875 Common rpmH 50S ribosomal protein L34 gbs1836 189 None None None 25011091 Common - hypothetical protein gbs1037 33 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 25011463 Common - 2-dehydropantoate 2-reductase gbs1421 129 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 25011840 Common - hypothetical protein gbs1801 128 COG0456 RimI, Acetyltransferases General function prediction only 25010550 Pathogen - hypothetical protein gbs0479 2 None None None 25011458 Common - hypothetical protein gbs1416 143 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 25010800 Common rnc ribonuclease III gbs0745 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 25010404 Common - hypothetical protein gbs0330 81 COG1846 MarR, Transcriptional regulators Transcription 25011730 Common - hypothetical protein gbs1690 123 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 25011354 Common scpB streptococcal C5a peptidase gbs1308 66 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 25011962 Common - hypothetical protein gbs1923 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 25011078 Common - hypothetical protein gbs1024 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 25011390 Common - hypothetical protein gbs1348 8 None None None 25010790 Pathogen - hypothetical protein gbs0735 1 None None None 25010382 Common - hypothetical protein gbs0308 9 COG4758 COG4758, Predicted membrane protein Function unknown 25010197 Common - hypothetical protein gbs0122 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25011328 Common - hypothetical protein gbs1279 12 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 25011891 Common - putative L-xylulose 5-phosphate 3-epimerase gbs1852 27 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 25010708 Common cylF hypothetical protein gbs0652 102 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 25010893 Common - hypothetical protein gbs0838 40 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 25011829 Pathogen - hypothetical protein gbs1790 1 None None None 25011151 Common - hypothetical protein gbs1100 237 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 25011377 Common - galactose-6-phosphate isomerase subunit LacB gbs1335 129 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 25011657 Common - hypothetical protein gbs1617 27 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 25010457 Common - hypothetical protein gbs0384 11 None None None 25011348 Common - hypothetical protein gbs1299 8 None None None 25010101 Common - phosphoribosylaminoimidazole synthetase gbs0026 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 25010662 Common - hypothetical protein gbs0597 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25011451 Common - hypothetical protein gbs1409 55 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 25011761 Common - hypothetical protein gbs1721 118 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 25010541 Common - hypothetical protein gbs0470 27 None None None 25011810 Common - DNA polymerase IV gbs1771 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 25010674 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase gbs0610 231 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 25011295 Common cpsC hypothetical protein gbs1245 29 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 25010843 Common - hypothetical protein gbs0788 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 25010881 Common - hypothetical protein gbs0826 86 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 25010719 Common - hypothetical protein gbs0664 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 25010517 Common - hypothetical protein gbs0444 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 25010680 Common - hypothetical protein gbs0616 23 COG4283 COG4283, Uncharacterized conserved protein Function unknown 25011599 Common - hypothetical protein gbs1558 2 None None None 25011028 Common - hypothetical protein gbs0975 3 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 25011633 Common - hypothetical protein gbs1592 2 None None None 25011495 Common rpmI 50S ribosomal protein L35 gbs1453 128 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 25011265 Common - hypothetical protein gbs1216 4 None None None 25010829 Common - hypothetical protein gbs0774 96 COG2606 EbsC, Uncharacterized conserved protein Function unknown 25010327 Common - hypothetical protein gbs0253 5 None None None 25010576 Common - hypothetical protein gbs0506 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 25010344 Common - hypothetical protein gbs0270 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 25012048 Common - hypothetical protein gbs2010 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 25011266 Pathogen - hypothetical protein gbs1217 1 None None None 25011788 Common - hypothetical protein gbs1749 17 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 25011124 Common - hypothetical protein gbs1073 24 COG1511 COG1511, Predicted membrane protein Function unknown 25010380 Common - hypothetical protein gbs0306 134 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 25010189 Common - hypothetical protein gbs0114 151 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 25011845 Common glnA glutamine synthetase gbs1806 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 25010638 Common - acetoin reductase gbs0569 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 25010526 Common nrdF ribonucleotide-diphosphate reductase subunit beta gbs0453 61 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 25012163 Common - hypothetical protein gbs2128 6 COG3619 COG3619, Predicted membrane protein Function unknown 25010238 Common - hypothetical protein gbs0163 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 25011245 Common - hypothetical protein gbs1196 53 COG1476 COG1476, Predicted transcriptional regulators Transcription 25012076 Common - hypothetical protein gbs2038 25 COG3981 COG3981, Predicted acetyltransferase General function prediction only 25010841 Common recR recombination protein RecR gbs0786 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 25010879 Common pepB group B oligopeptidase PepB gbs0824 85 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 25011544 Common - hypothetical protein gbs1502 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 25010372 Common - hypothetical protein gbs0298 102 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 25011759 Common - transcriptional repressor CodY gbs1719 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 25012138 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase gbs2103 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 25011400 Common - hypothetical protein gbs1358 24 COG2253 COG2253, Uncharacterized conserved protein Function unknown 25011392 Pathogen - hypothetical protein gbs1350 1 None None None 25010858 Common - hypothetical protein gbs0803 115 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25010439 Pathogen - hypothetical protein gbs0365 1 None None None 25011588 Common - hypothetical protein gbs1546 138 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 25010342 Common - transketolase gbs0268 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 25011407 Pathogen - hypothetical protein gbs1365 1 None None None 25010092 Common - ribose-phosphate pyrophosphokinase gbs0017 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 25011220 Common - hypothetical protein gbs1169 165 COG0628 PerM, Predicted permease General function prediction only 25011289 Common cpsJ hypothetical protein gbs1239 218 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25011375 Common - tagatose 1,6-diphosphate aldolase gbs1333 24 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 25011851 Common fusA elongation factor G gbs1812 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 25010532 Common - hypothetical protein gbs0459 5 COG4367 COG4367, Uncharacterized protein conserved in bacteria Function unknown 25011053 Pathogen - hypothetical protein gbs1000 1 None None None 25010161 Pathogen - hypothetical protein gbs0086 1 None None None 25011600 Common - hypothetical protein gbs1559 1 None None None 25012007 Common - hypothetical protein gbs1969 2 None None None 25011129 Common - carbamoyl phosphate synthase small subunit gbs1078 238 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 25011741 Pathogen - hypothetical protein gbs1701 1 None None None 25010316 Pathogen - hypothetical protein gbs0242 1 None None None 25012124 Common - hypothetical protein gbs2089 149 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 25011750 Common - hypothetical protein gbs1710 165 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 25011631 Common - hypothetical protein gbs1590 80 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 25011966 Common relA hypothetical protein gbs1928 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 25010784 Pathogen - hypothetical protein gbs0729 1 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 25011742 Common - hypothetical protein gbs1702 77 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 25010870 Common - hypothetical protein gbs0815 5 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 25011720 Common - hypothetical protein gbs1680 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 25010273 Common pnpA polynucleotide phosphorylase/polyadenylase gbs0198 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 25010152 Common rplO 50S ribosomal protein L15 gbs0077 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 25011223 Common - hypothetical protein gbs1172 122 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25012099 Common hisS histidyl-tRNA synthetase gbs2061 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 25010406 Common acpP acyl carrier protein gbs0332 179 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 25011360 Common - hypothetical protein gbs1316 3 None None None 25011862 Common - hypothetical protein gbs1823 32 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 25011611 Common - hypothetical protein gbs1570 39 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 25011638 Common - hypothetical protein gbs1597 166 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 25011561 Common - hypothetical protein gbs1519 5 None None None 25011815 Common - hypothetical protein gbs1776 11 COG0730 COG0730, Predicted permeases General function prediction only 25010626 Common - hypothetical protein gbs0557 139 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 25011421 Common - hypothetical protein gbs1379 2 None None None 25011356 Common - hypothetical protein gbs1312 169 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 25011641 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase gbs1600 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 25011534 Common - hypothetical protein gbs1492 133 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 25011694 Common - hypothetical protein gbs1654 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 25011625 Common - hypothetical protein gbs1584 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 25012102 Common - hypothetical protein gbs2064 20 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 25010986 Common - hypothetical protein gbs0932 71 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 25011134 Common - hypothetical protein gbs1083 43 COG2966 COG2966, Uncharacterized conserved protein Function unknown 25011188 Pathogen - hypothetical protein gbs1137 1 None None None 25011010 Pathogen - hypothetical protein gbs0956 3 None None None 25011995 Common - hypothetical protein gbs1957 14 COG4815 COG4815, Uncharacterized protein conserved in bacteria Function unknown 25010243 Common - hypothetical protein gbs0168 63 COG1476 COG1476, Predicted transcriptional regulators Transcription 25011108 Pathogen - hypothetical protein gbs1054 1 None None None 25010194 Common - hypothetical protein gbs0119 71 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 25011956 Common - galactose-6-phosphate isomerase subunit LacB gbs1917 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 25010489 Common - hypothetical protein gbs0416 20 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 25010742 Common - hypothetical protein gbs0687 2 COG3212 COG3212, Predicted membrane protein Function unknown 25011481 Common - hypothetical protein gbs1439 14 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 25011895 Common ulaA ascorbate-specific PTS system enzyme IIC gbs1856 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 25011278 Common - DNA topoisomerase IV subunit B gbs1229 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 25010078 Common - hypothetical protein gbs0003 59 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 25010864 Common - hypothetical protein gbs0809 29 COG3711 BglG, Transcriptional antiterminator Transcription 25011202 Pathogen - hypothetical protein gbs1151 1 None None None 25011640 Common - hypothetical protein gbs1599 7 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 25010900 Common - hypothetical protein gbs0845 78 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 25011575 Common glnP glutamine ABC transporter permease and substrate binding protein gbs1533 190 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 25010250 Common - hypothetical protein gbs0175 90 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 25011595 Common coaE dephospho-CoA kinase gbs1553 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 25011590 Common - hypothetical protein gbs1548 192 COG0557 VacB, Exoribonuclease R Transcription 25010148 Common rplF 50S ribosomal protein L6 gbs0073 230 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 25010948 Common - hypothetical protein gbs0894 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 25011081 Common - hypothetical protein gbs1027 138 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 25010755 Pathogen - hypothetical protein gbs0700 1 None None None 25010568 Common - hypothetical protein gbs0498 3 None None None 25010976 Common - hypothetical protein gbs0922 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 25010556 Common - hypothetical protein gbs0486 135 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 25011231 Common - hypothetical protein gbs1180 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 25011016 Common - hypothetical protein gbs0963 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25010309 Common - hypothetical protein gbs0235 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 25011869 Common - hypothetical protein gbs1830 13 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 25010200 Common - fructose-bisphosphate aldolase gbs0125 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 25010994 Common - hypothetical protein gbs0940 125 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 25010084 Common - hypothetical protein gbs0009 47 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 25010210 Common - adaptor protein gbs0135 12 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 25010778 Common - hypothetical protein gbs0723 23 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 25010141 Common rpmC 50S ribosomal protein L29 gbs0066 19 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 25011037 Pathogen - hypothetical protein gbs0984 1 None None None 25011090 Common - hypothetical protein gbs1036 10 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 25010732 Pathogen - hypothetical protein gbs0677 4 COG0546 Gph, Predicted phosphatases General function prediction only 25012065 Common - hypothetical protein gbs2027 69 COG2188 PhnF, Transcriptional regulators Transcription 25011709 Common - hypothetical protein gbs1669 15 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 25010807 Pathogen - hypothetical protein gbs0752 1 None None None 25011145 Common - hypothetical protein gbs1094 107 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 25011971 Common - hypothetical protein gbs1933 127 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 25012116 Common - hypothetical protein gbs2081 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 25010941 Common pheS phenylalanyl-tRNA synthetase subunit alpha gbs0886 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 25010156 Common rpmJ 50S ribosomal protein L36 gbs0081 139 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 25010455 Common - hypothetical protein gbs0382 6 None None None 25011564 Common secY preprotein translocase subunit SecY gbs1522 220 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 25010953 Common - hypothetical protein gbs0899 84 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 25010388 Common - hypothetical protein gbs0314 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 25010886 Common - hypothetical protein gbs0831 30 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 25012157 Common - arginine deiminase gbs2122 56 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 25010240 Common - hypothetical protein gbs0165 1 None None None 25011193 Pathogen - hypothetical protein gbs1142 1 None None None 25011773 Common - hypothetical protein gbs1733 27 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 25011685 Common xerD site-specific tyrosine recombinase XerD-like protein gbs1645 2 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 25010413 Common - acetyl-CoA carboxylase biotin carboxylase subunit gbs0339 237 COG0439 AccC, Biotin carboxylase Lipid metabolism 25011525 Common - hypothetical protein gbs1483 3 COG4713 COG4713, Predicted membrane protein Function unknown 25011885 Common - hypothetical protein gbs1846 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 25011988 Common - hypothetical protein gbs1950 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 25011061 Pathogen - hypothetical protein gbs1008 1 None None None 25011716 Common gidB glucose-inhibited division protein B gbs1676 195 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 25010145 Common rplE 50S ribosomal protein L5 gbs0070 247 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 25010583 Common - hypothetical protein gbs0514 12 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 25010966 Common - hypothetical protein gbs0912 40 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 25011978 Common - hypothetical protein gbs1940 6 None None None 25010218 Common - hypothetical protein gbs0143 139 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 25010932 Common atpF F0F1 ATP synthase subunit B gbs0877 139 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 25011933 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase gbs1894 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 25011476 Common - pyrimidine regulatory protein PyrR gbs1434 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 25010765 Pathogen - hypothetical protein gbs0710 1 None None None