Brucella suis 1330 chromosome II, complete sequence NC_004311 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 23500837 Common znuA zinc ABC transporter, periplasmic zinc-binding protein BRA1122 158 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 23499972 Common - hypothetical protein BRA0213 24 None None None 23500192 Common glpK glycerol kinase BRA0443 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 23500768 Common - hypothetical protein BRA1046 108 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 23500053 Common narH respiratory nitrate reductase, beta subunit BRA0298 149 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 23500903 Common - tonB dependent receptor domain protein BRA1190 60 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 23499885 Common flhB flagellar biosynthesis protein FlhB BRA0121 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 23499811 Common - formiminoglutamase, putative BRA0044 58 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 23500182 Common - glutamate-1-semialdehyde 2,1-aminomutase BRA0433 234 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 23500203 Common def peptide deformylase BRA0454 210 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 23500882 Common - transcriptional regulator, IclR family BRA1169 108 COG1414 IclR, Transcriptional regulator Transcription 23500626 Common arcB ornithine cyclodeaminase BRA0899 84 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 23499836 Common - type IV secretion system protein VirB1 BRA0069 26 None None None 23500371 Common - hypothetical protein BRA0627 9 None None None 23500849 Common flgD flagellar basal body rod modification protein BRA1134 103 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 23499815 Pathogen - hypothetical protein BRA0048 2 None None None 23500526 Common - peptidase, S24 family BRA0792 20 COG2932 COG2932, Predicted transcriptional regulator Transcription 23500029 Pathogen - hypothetical protein BRA0273 1 None None None 23499778 Common - hypothetical protein BRA0011 7 COG5664 COG5664, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 23500369 Pathogen - hypothetical protein BRA0625 1 None None None 23500489 Common - hypothetical protein BRA0752 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 23499963 Common ileS isoleucyl-tRNA synthetase BRA0202 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23500360 Common - hypothetical protein BRA0616 27 COG3391 COG3391, Uncharacterized conserved protein Function unknown 23500595 Common eryD erythritol transcriptional regulator BRA0867 65 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 23500474 Common - hypothetical protein BRA0737 62 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 23500589 Common - hypothetical protein BRA0861 10 COG5618 COG5618, Predicted periplasmic lipoprotein General function prediction only 23500258 Common cydB cytochrome d ubiquinol oxidase, subunit II BRA0511 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 23500084 Common - spermidine/putrescine ABC transporter, permease protein BRA0329 232 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 23499842 Common - SPFH domain/Band 7 family protein BRA0075 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 23499822 Common gltD glutamate synthase subunit beta BRA0055 188 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 23500853 Common flgK flagellar hook-associated protein FlgK BRA1138 107 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 23500798 Common - aldehyde dehydrogenase family protein BRA1076 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23500260 Common - transcriptional regulator, GntR family BRA0513 132 COG2188 PhnF, Transcriptional regulators Transcription 23500323 Common mfd transcription-repair coupling factor BRA0579 218 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 23500357 Common - hypothetical protein BRA0613 21 None None None 23500262 Pathogen - hypothetical protein BRA0515 1 None None None 23499917 Common flgA flagellar basal body P-ring biosynthesis protein FlgA BRA0155 26 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 23500865 Common xylG D-xylose ABC transporter, ATP-binding protein BRA1151 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23499768 Common repC replication initiation protein RepC BRA0001 17 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 23500022 Common - sugar ABC transporter, periplasmic sugar-binding protein, putative BRA0265 73 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 23499984 Common - transcriptional regulator, MerR family BRA0226 138 COG0789 SoxR, Predicted transcriptional regulators Transcription 23500630 Common - transcriptional regulator, ArsR family BRA0903 37 COG0640 ArsR, Predicted transcriptional regulators Transcription 23500137 Common - hypothetical protein BRA0384 28 COG0348 NapH, Polyferredoxin Energy production and conversion 23500198 Common - 3-hydroxyacyl-CoA dehydrogenase, putative BRA0449 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500239 Common bioB biotin synthase BRA0492 186 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 23500580 Common - aminotransferase, class III BRA0851 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 23500501 Common xseA exodeoxyribonuclease VII large subunit BRA0764 203 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 23500230 Common - amino acid carrier family protein BRA0483 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 23500800 Common - peptide ABC transporter, ATP-binding protein BRA1078 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 23499772 Common - ribokinase, putative BRA0005 203 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 23499858 Common - hypothetical protein BRA0094 2 None None None 23500212 Common - HlyD family secretion protein BRA0463 109 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 23500093 Common - glutaminase BRA0340 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 23500045 Common - peptidase, U32 family BRA0290 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 23500758 Common - hypothetical protein BRA1036 123 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 23500823 Common - polyamine ABC transporter, permease protein, putative BRA1106 213 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 23500602 Common - conserved hypothetical protein TIGR00257 BRA0874 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 23500313 Common - ABC transporter, permease protein BRA0569 107 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 23500703 Pathogen - hypothetical protein BRA0977 1 None None None 23499787 Common - hypothetical protein BRA0020 3 None None None 23500542 Common - ABC transporter, periplasmic substrate-binding protein BRA0810 11 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 23499892 Common fliI flagellum-specific ATP synthase BRA0129 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 23500158 Common - dihydrodipicolinate synthase family protein BRA0406 233 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 23499845 Common - homospermidine synthase BRA0078 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 23500113 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase BRA0360 33 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 23500393 Common - branched-chain amino acid ABC transporter, permease protein BRA0649 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 23500429 Common - drug resistance transporter, Bcr/CflA family BRA0687 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500477 Common - glycine betaine/L-proline ABC transporter, ATP-binding protein BRA0740 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 23499953 Common fumC fumarate hydratase BRA0192 231 COG0114 FumC, Fumarase Energy production and conversion 23500168 Common - exopolysaccharide biosynthesis protein Bme11 BRA0417 67 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 23500693 Common - hypothetical protein BRA0967 16 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 23500005 Common norC nitric-oxide reductase, small subunit BRA0248 36 None None None 23500553 Common - hypothetical protein BRA0823 61 COG0730 COG0730, Predicted permeases General function prediction only 23499911 Common - hypothetical protein BRA0148 58 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 23500610 Common leuD isopropylmalate isomerase small subunit BRA0883 211 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 23500380 Common pcaF beta-ketoadipyl CoA thiolase BRA0636 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 23500161 Common - peptide ABC transporter, periplasmic peptide-binding protein BRA0409 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23500052 Common narJ respiratory nitrate reductase, delta subunit BRA0297 57 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 23500224 Pathogen - hypothetical protein BRA0477 1 None None None 23500784 Pathogen - hypothetical protein BRA1062 1 None None None 23500531 Pathogen - hypothetical protein BRA0797 1 None None None 23500016 Pathogen - hypothetical protein BRA0259 1 None None None 23500438 Pathogen - hypothetical protein BRA0698 1 None None None 23500734 Common - peptide ABC transporter, permease protein BRA1011 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500282 Common - oligopeptide ABC transporter, permease protein BRA0535 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500751 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase BRA1028 139 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 23500062 Common - sugar ABC transporter, ATP-binding protein BRA0307 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 23500292 Common ugd UDP-glucose 6-dehydrogenase BRA0545 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 23500710 Common - creatinine amidohydrolase, putative BRA0986 81 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 23499862 Common - hypothetical protein BRA0097 32 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 23500373 Pathogen - hypothetical protein BRA0629 1 None None None 23499999 Pathogen - hypothetical protein BRA0242 1 None None None 23500252 Common - putative monovalent cation/H+ antiporter subunit G BRA0505 24 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 23500645 Common - hypothetical protein BRA0918 5 None None None 23499803 Pathogen - hypothetical protein BRA0036 1 None None None 23500497 Common - hypothetical protein BRA0760 54 COG1289 COG1289, Predicted membrane protein Function unknown 23500328 Common ccdA cytochrome c-type biogenesis protein CcdA BRA0584 102 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 23499997 Common - malate/L-lactate dehydrogenase family protein BRA0240 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 23500148 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase BRA0396 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500504 Pathogen - hypothetical protein BRA0767 1 None None None 23500277 Common - cell division protein FtsK, putative BRA0530 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 23500342 Common - acyl-CoA dehydrogenase family protein BRA0598 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 23500409 Common - hypothetical protein BRA0666 77 COG2962 RarD, Predicted permeases General function prediction only 23500607 Common - glyoxalase family protein BRA0879 20 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 23500384 Common pobR pobR protein BRA0640 99 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23500396 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA0652 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23500686 Common - lipoprotein, YaeC family BRA0960 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 23500337 Pathogen - hypothetical protein BRA0593 1 None None None 23500361 Pathogen - hypothetical protein BRA0617 1 None None None 23500433 Common - sugar ABC transporter, permease protein, putative BRA0692 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23499780 Common entA 2,3-dihydroxybenzoate-2,3-dehydrogenase BRA0013 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500298 Pathogen - IS711, transposase orfA BRA0552 1 None None None 23500248 Common - putative monovalent cation/H+ antiporter subunit C BRA0501 98 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 23500656 Common hutI imidazolonepropionase BRA0929 98 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 23500242 Pathogen - hypothetical protein BRA0495 1 None None None 23500678 Common - transcriptional regulator, LysR family BRA0952 153 COG0583 LysR, Transcriptional regulator Transcription 23500521 Common - hypothetical protein BRA0787 4 None None None 23500895 Common - sugar ABC transporter, permease protein, putative BRA1182 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23500490 Pathogen - hypothetical protein BRA0753 1 None None None 23499872 Common - glycosyl transferase, group 2 family protein BRA0107 23 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 23500402 Common ugpC glycerol-3-phosphate ABC transporter, ATP-binding protein BRA0658 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 23500368 Pathogen - hypothetical protein BRA0624 1 None None None 23500774 Common gpm phosphoglyceromutase BRA1052 181 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 23500241 Pathogen - hypothetical protein BRA0494 2 None None None 23500565 Pathogen - hypothetical protein BRA0835 1 None None None 23500376 Common - amino acid ABC transporter, periplasmic amino acid-binding protein BRA0632 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23500618 Common - hypothetical protein BRA0891 95 COG2835 COG2835, Uncharacterized conserved protein Function unknown 23500075 Pathogen - hypothetical protein BRA0320 1 None None None 23499968 Common - hypothetical protein BRA0209 97 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 23500270 Pathogen - hypothetical protein BRA0523 1 None None None 23500141 Common - heme-thiolate monooxygenase, putative BRA0388 66 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 23500624 Pathogen - hypothetical protein BRA0897 1 None None None 23500466 Common - pyridine nucleotide-disulphide oxidoreductase family protein BRA0729 240 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 23500635 Common - aldehyde dehydrogenase family protein BRA0908 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23499942 Common glcD glycolate oxidase, subunit GlcD BRA0180 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 23500227 Common - transcriptional regulator, MarR family BRA0480 87 COG1846 MarR, Transcriptional regulators Transcription 23500256 Common - ABC transporter, ATP-binding/permease protein BRA0509 245 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 23500082 Common - spermidine/putrescine ABC transporter, ATP-binding protein, putative BRA0327 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 23499928 Common - CAIB/BAIF family protein BRA0166 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 23499933 Pathogen - hypothetical protein BRA0171 1 None None None 23499975 Common lpxK tetraacyldisaccharide 4'-kinase BRA0216 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 23499776 Common - ABC transporter, ATP-binding protein BRA0009 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 23499961 Pathogen - hypothetical protein BRA0200 1 None None None 23500540 Common - ABC transporter, permease protein BRA0807 102 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 23500472 Common - immunoreactive 14 kDa protein BA14k BRA0735 7 None None None 23500587 Common rbsC-3 ribose ABC transporter, permease protein BRA0859 111 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 23500604 Common mgtE magnesium transporter BRA0876 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 23500745 Common rnpA ribonuclease P BRA1022 58 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 23500030 Common - transcriptional regulator NosR, putative BRA0274 87 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 23499801 Common - shikimate dehydrogenase family protein BRA0034 203 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 23500840 Common - transcriptional regulator, Fur family BRA1125 92 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 23500038 Common - hypothetical protein BRA0283 58 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 23500778 Pathogen - hypothetical protein BRA1056 1 None None None 23499818 Common ibpA 16 kDa heat shock protein A BRA0051 68 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 23499813 Common - lysophospholipase L2, putative BRA0046 66 COG2267 PldB, Lysophospholipase Lipid metabolism 23500563 Common - hypothetical protein BRA0833 3 None None None 23500818 Common - peptide ABC transporter, permease protein, putative BRA1099 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23499943 Common glcE glycolate oxidase, subunit GlcE BRA0181 157 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 23500755 Common - hypothetical protein BRA1032 7 None None None 23500303 Common - IS66 family element, orf1, transposase, putative BRA0558 26 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500404 Common - cytidine/deoxycytidylate deaminase family protein BRA0660 13 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 23500180 Common - hypothetical protein BRA0431 22 COG2327 WcaK, Uncharacterized conserved protein Function unknown 23500398 Common - renal dipeptidase family protein BRA0654 103 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 23500456 Common - ABC transporter, ATP-binding protein BRA0718 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 23499891 Common flgF flagellar basal body rod protein FlgF BRA0128 123 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 23500194 Common - transcriptional regulator, LysR family BRA0445 183 COG0583 LysR, Transcriptional regulator Transcription 23500458 Common - ABC transporter, periplasmic substrate-binding protein BRA0720 126 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 23500672 Pathogen - hypothetical protein BRA0946 1 None None None 23500089 Common - hydrophobe/amphiphile efflux-1 family protein BRA0334 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 23500059 Common - sugar ABC transporter, periplasmic sugar-binding protein BRA0304 107 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23500205 Common - transcriptional regulator, ArsR family BRA0456 165 COG0640 ArsR, Predicted transcriptional regulators Transcription 23500139 Common - acetate kinase BRA0386 161 COG0282 ackA, Acetate kinase Energy production and conversion 23499925 Common - transcriptional regulator, LysR family BRA0163 187 COG0583 LysR, Transcriptional regulator Transcription 23500237 Common bioD dithiobiotin synthetase BRA0490 154 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 23499774 Common - ABC transporter, permease protein BRA0007 81 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 23500802 Common - peptide ABC transporter, permease protein BRA1080 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500070 Common nrdI ribonucleotide reductase stimulatory protein BRA0315 38 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 23500095 Pathogen - hypothetical protein BRA0342 1 None None None 23499783 Common entC isochorismate synthase BRA0016 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 23500855 Common - transcriptional regulator BRA1140 92 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23500321 Common - frnE protein, putative BRA0577 85 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 23500353 Common rpmG 50S ribosomal protein L33 BRA0609 123 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 23500788 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase BRA1066 215 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 23500667 Common - dihydroxy-acid dehydratase BRA0940 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 23500889 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA1176 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23499851 Common - rhodanese family protein BRA0086 116 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 23499906 Common - phthalate transporter, putative BRA0143 145 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 23499838 Common galU UTP--glucose-1-phosphate uridylyltransferase BRA0071 225 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 23500130 Common - hypothetical protein BRA0377 25 COG5293 COG5293, Uncharacterized protein conserved in bacteria Function unknown 23499915 Common fliE flagellar hook-basal body protein FliE BRA0153 21 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 23500507 Common - D-amino acid oxidase family protein BRA0770 130 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 23500355 Pathogen - hypothetical protein BRA0611 1 None None None 23500867 Pathogen - hypothetical protein BRA1153 1 None None None 23499986 Common - sensor histidine kinase BRA0228 189 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 23500884 Common - aldehyde dehydrogenase family protein BRA1171 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23500345 Common - hypothetical protein BRA0601 170 COG0344 COG0344, Predicted membrane protein Function unknown 23500002 Common - hypothetical protein BRA0245 3 None None None 23500628 Common - transcriptional regulator, AsnC family BRA0901 139 COG1522 Lrp, Transcriptional regulators Transcription 23500593 Common eryB glycerol-3-phosphate dehydrogenase BRA0865 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 23500533 Common nikE nickel transporter ATP-binding protein BRA0800 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500007 Common - CbbQ/NirQ/NorQ/GpvN family protein BRA0250 78 COG0714 COG0714, MoxR-like ATPases General function prediction only 23500576 Common - IS711, transposase orfB BRA0847 55 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500151 Common - aldehyde dehydrogenase family protein BRA0399 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23500411 Common - hypothetical protein BRA0669 40 COG0730 COG0730, Predicted permeases General function prediction only 23500669 Common - hypothetical protein BRA0942 14 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 23500050 Common - peptidyl-prolyl cis-trans isomerase, putative BRA0295 123 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 23499860 Common - hypothetical protein BRA0095 2 None None None 23500315 Common qor quinone oxidoreductase BRA0571 187 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 23500064 Common - oxidoreductase, Gfo/Idh/MocA family BRA0309 158 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23500809 Common - penicillin amidase family protein BRA1089 75 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 23500065 Pathogen - hypothetical protein BRA0310 1 None None None 23500284 Common - oligopeptide ABC transporter, periplasmic oligopeptide-binding protein BRA0537 213 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 23500696 Common - oxidoreductase, putative BRA0970 45 COG4091 COG4091, Predicted homoserine dehydrogenase Amino acid transport and metabolism 23500378 Common - transcriptional regulator, AsnC family BRA0634 148 COG1522 Lrp, Transcriptional regulators Transcription 23500558 Common - hypothetical protein BRA0828 6 None None None 23500073 Pathogen - hypothetical protein BRA0318 1 None None None 23500428 Common - ribosomal RNA large subunit methyltransferase J, putative BRA0686 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 23500860 Common fliF flagellar MS-ring protein BRA1146 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 23500712 Common - WD-repeat family protein BRA0988 47 COG2319 COG2319, FOG: WD40 repeat General function prediction only 23500637 Common - hypothetical protein BRA0910 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 23500147 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA0395 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23500598 Common - ribose-5-phosphate isomerase B BRA0870 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 23500435 Pathogen - hypothetical protein BRA0694 1 None None None 23500000 Common - hypothetical protein BRA0243 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 23500305 Common - conserved hypothetical protein TIGR00011 BRA0561 82 COG2606 EbsC, Uncharacterized conserved protein Function unknown 23500133 Pathogen - hypothetical protein BRA0380 1 None None None 23500525 Common - hypothetical protein BRA0791 11 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 23500705 Pathogen - hypothetical protein BRA0980 1 None None None 23500040 Common - ABC transporter, permease protein BRA0285 176 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 23500515 Common pgl 6-phosphogluconolactonase BRA0779 120 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 23500334 Common - hypothetical protein BRA0590 142 COG2962 RarD, Predicted permeases General function prediction only 23499904 Common - SyrB family protein, putative BRA0141 13 None None None 23500294 Common - endoglucanase family protein BRA0547 21 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 23500643 Common - HlyD family secretion protein BRA0916 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 23499847 Common - para-aminobenzoate synthase component I BRA0080 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 23500072 Common nrdF ribonucleotide-diphosphate reductase subunit beta BRA0317 147 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 23500214 Common - hypothetical protein BRA0466 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 23500206 Common - hypothetical protein BRA0457 73 COG2391 COG2391, Predicted transporter component General function prediction only 23500902 Common - ROK family protein BRA1189 168 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23500441 Common - iron compound ABC transporter, ATP-binding protein, putative BRA0701 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 23500551 Pathogen - hypothetical protein BRA0821 1 None None None 23500175 Common - Bme2 protein BRA0426 35 COG1434 COG1434, Uncharacterized conserved protein Function unknown 23500469 Common - glutamine synthetase family protein BRA0732 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 23500423 Common - hydantoinase/oxoprolinase family protein BRA0681 114 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 23500548 Common - crcB family protein BRA0818 157 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 23500109 Common - hypothetical protein BRA0356 2 None None None 23500244 Common - hypothetical protein BRA0497 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 23500721 Common - transcriptional regulator, IclR family BRA0997 100 COG1414 IclR, Transcriptional regulator Transcription 23500893 Common - sugar ABC transporter, periplasmic sugar-binding protein, putative BRA1180 101 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23499990 Common - oxidoreductase, FAD-binding, putative BRA0233 94 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 23500781 Common - endonuclease/exonuclease/phosphatase family protein BRA1059 74 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 23500274 Common lpdA-3 dihydrolipoamide dehydrogenase BRA0527 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 23500251 Common phaF putative monovalent cation/H+ antiporter subunit F BRA0504 43 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 23500492 Common - iron compound ABC transporter, permease protein BRA0755 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 23500658 Common hutG formiminoglutamase BRA0931 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 23499782 Common entE enterobactin synthase subunit E BRA0015 221 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 23499874 Common - oxidoreductase, Gfo/Idh/MocA family BRA0109 161 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23499789 Common - hypothetical protein BRA0022 18 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 23500221 Common - transcriptional regulatory protein OmpR, putative BRA0474 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23500057 Common - sugar-binding protein, putative BRA0302 126 COG1609 PurR, Transcriptional regulators Transcription 23500385 Common pobA 4-hydroxybenzoate 3-monooxygenase BRA0641 71 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 23500650 Common alr alanine racemase BRA0923 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 23499853 Common modA molybdenum ABC transporter, periplasmic molybdenum-binding protein BRA0088 149 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 23500156 Common - peptide ABC transporter, ATP-binding protein BRA0404 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 23499898 Common - glycosyl transferase, group 2 family protein BRA0135 144 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23500684 Common - oxidoreductase, GMC family BRA0958 91 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 23499935 Common - outer membrane autotransporter BRA0173 67 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 23500416 Pathogen - hypothetical protein BRA0674 1 None None None 23500326 Common glmS D-fructose-6-phosphate amidotransferase BRA0582 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 23500829 Common - pemK family protein BRA1113 21 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 23500119 Common - trbL protein BRA0366 40 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 23499977 Common mutL DNA mismatch repair protein BRA0218 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 23500874 Common - 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase BRA1161 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23500871 Pathogen - hypothetical protein BRA1157 1 None None None 23500835 Common - cobalamin synthesis protein/P47K family protein BRA1120 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 23500350 Common - hypothetical protein BRA0606 30 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 23500534 Common nikD nickel transporter ATP-binding protein BRA0801 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500344 Common pyrC-2 dihydroorotase BRA0600 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 23500470 Pathogen - hypothetical protein BRA0733 1 None None None 23500708 Common - glycerate dehydrogenase BRA0983 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 23500857 Common - motD-related protein BRA1142 7 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 23500102 Common - hypothetical protein BRA0349 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 23500268 Common - sugar ABC transporter, ATP-binding protein BRA0521 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 23500609 Pathogen - hypothetical protein BRA0882 1 None None None 23500486 Common - sugar ABC transporter, permease protein, putative BRA0749 163 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23500728 Common - GGDEF domain protein BRA1004 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 23500287 Common - hypothetical protein BRA0540 12 COG5455 COG5455, Predicted integral membrane protein Function unknown 23500616 Common - ada regulatory protein, putative BRA0889 158 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 23500816 Common - oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, putative BRA1097 188 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23500761 Common lepA GTP-binding protein LepA BRA1039 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 23500530 Pathogen - hypothetical protein BRA0796 1 None None None 23500255 Common cydD ABC transporter, ATP-binding protein CydD BRA0508 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 23500003 Common - cytochrome c oxidase, subunit III BRA0246 151 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 23500117 Common - repA-related protein BRA0364 33 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 23499993 Common - hypothetical protein BRA0236 29 COG2510 COG2510, Predicted membrane protein Function unknown 23499949 Common hisS histidyl-tRNA synthetase BRA0187 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23500664 Common - sugar ABC transporter, periplasmic sugar-binding protein BRA0937 92 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 23500822 Common - polyamine ABC transporter, permease protein BRA1105 209 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 23500122 Pathogen - hypothetical protein BRA0369 1 None None None 23500320 Common - peptide ABC transporter, periplasmic peptide-binding protein BRA0576 180 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 23500795 Common - IS3 family element, transposase orfA BRA1073 73 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500718 Common rbsC-5 ribose ABC transporter, permease protein BRA0994 125 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 23500366 Common - hypothetical protein BRA0622 5 None None None 23500178 Common - polysaccharide biosynthesis protein BRA0429 80 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 23499799 Common - acetoin dehydrogenase, alpha/beta subunit, putative BRA0032 160 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 23499988 Common - hypothetical protein BRA0231 11 COG5591 COG5591, Uncharacterized conserved protein Function unknown 23500363 Pathogen - hypothetical protein BRA0619 1 None None None 23500499 Common - conserved hypothetical protein TIGR00046 BRA0762 128 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 23500289 Common - NAD-dependent epimerase/dehydratase family protein BRA0542 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 23500107 Common oxyR transcriptional regulator OxyR BRA0354 186 COG0583 LysR, Transcriptional regulator Transcription 23500234 Common - glycosyl hydrolase, family 25 BRA0487 46 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 23499923 Pathogen - hypothetical protein BRA0161 1 None None None 23499983 Common - CAIB/BAIF family protein BRA0224 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 23500711 Common - cobalamin synthesis protein/P47K family protein BRA0987 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 23500027 Common - hypothetical protein BRA0270 26 None None None 23500887 Common - branched-chain amino acid ABC transporter, permease protein BRA1174 94 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 23500480 Common - amino acid processing enzyme-related protein BRA0743 69 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 23500041 Common - ABC transporter, ATP binding protein BRA0286 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 23500555 Common - hypothetical protein BRA0825 46 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 23500097 Common - EAL domain protein BRA0344 161 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 23499833 Common - type IV secretion system protein VirB4 BRA0066 59 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 23500569 Common - hypothetical protein BRA0839 9 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 23500331 Common - hypothetical protein BRA0587 7 None None None 23499912 Pathogen - hypothetical protein BRA0150 1 None None None 23500407 Pathogen - hypothetical protein BRA0664 1 None None None 23500207 Common - hypothetical protein BRA0458 69 COG2391 COG2391, Predicted transporter component General function prediction only 23500181 Common - glycosyl transferase, group 1 family protein BRA0432 206 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 23500673 Common - D-aminopeptidase BRA0947 91 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 23500173 Common omp31-2 outer membrane protein, 31 kDa BRA0423 26 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 23500453 Common iolD TPP-requiring enzyme IolD BRA0714 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 23500485 Common - sugar ABC transporter, periplasmic sugar-binding protein, putative BRA0748 130 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23500582 Common - hypothetical protein BRA0853 40 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 23500157 Common - peptide ABC transporter, ATP-binding protein BRA0405 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23499881 Common - drug resistance transporter, Bcr/CflA family BRA0116 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500036 Common - nosX protein BRA0280 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 23500020 Common - sugar-binding transcriptional regulator, LacI family BRA0263 90 COG1609 PurR, Transcriptional regulators Transcription 23499819 Common - threonine aldolase, low-specificity, putative BRA0052 100 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 23500522 Common - carbonic anhydrase BRA0788 147 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 23499931 Pathogen - hypothetical protein BRA0169 1 None None None 23500187 Common - methyltransferase, putative BRA0438 43 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 23500077 Common minD septum site-determining protein MinD BRA0322 139 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 23500318 Common - hypothetical protein BRA0574 43 COG3785 COG3785, Uncharacterized conserved protein Function unknown 23499878 Common - spermidine/putrescine ABC transporter, permease protein, putative BRA0113 185 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 23499940 Common - transcriptional regulator, LysR family BRA0178 109 COG0583 LysR, Transcriptional regulator Transcription 23499827 Common - type IV secretion system protein VirB10 BRA0060 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 23500907 Common - branched-chain amino acid ABC transporter, permease protein BRA1194 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 23500900 Common - taurine ABC transporter, ATP-binding protein BRA1187 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 23500845 Pathogen - hypothetical protein BRA1130 2 None None None 23500088 Common - hypothetical protein BRA0333 2 None None None 23499871 Pathogen - hypothetical protein BRA0106 1 None None None 23500915 Common - replication protein RepB BRA1203 53 COG1475 Spo0J, Predicted transcriptional regulators Transcription 23500786 Common coaBC bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase BRA1064 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 23500591 Pathogen - hypothetical protein BRA0863 1 None None None 23499967 Common - conserved hypothetical protein TIGR00095 BRA0207 214 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 23500738 Common - transcriptional regulator, GntR family BRA1015 131 COG1802 GntR, Transcriptional regulators Transcription 23500418 Common - iron compound ABC transporter, permease protein BRA0676 189 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 23500726 Common - glutathione S-transferase, putative BRA1002 83 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 23500510 Common - transcriptional regulator, AsnC family BRA0773 164 COG1522 Lrp, Transcriptional regulators Transcription 23500560 Pathogen - hypothetical protein BRA0830 1 None None None 23500145 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative BRA0392 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23499890 Common - hypothetical protein BRA0127 20 None None None 23500614 Common asd aspartate-semialdehyde dehydrogenase BRA0887 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 23500766 Common - glutathione S-transferase family protein BRA1044 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 23500443 Common sodC superoxide dismutase, Cu-Zn BRA0703 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 23500682 Common - branched-chain amino acid ABC transporter, permease protein BRA0956 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 23499954 Common - hypothetical protein BRA0193 3 None None None 23500266 Common - sugar ABC transporter, permease protein BRA0519 167 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23500641 Common - AcrB/AcrD/AcrF multidrug efflux protein BRA0914 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 23500909 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA1197 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23500792 Common - hypothetical protein BRA1070 6 None None None 23500346 Common - DNA processing protein DprA, putative BRA0602 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 23500817 Common - peptide ABC transporter, permease protein BRA1098 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23499876 Common gnd 6-phosphogluconate dehydrogenase BRA0111 179 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 23500652 Common - transcriptional regulator, putative BRA0925 102 COG1396 HipB, Predicted transcriptional regulators Transcription 23499888 Common - flagellar motor switch protein FliM, putative BRA0125 51 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 23500689 Common - glyoxalase family protein BRA0963 53 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 23500475 Common - glycine betaine/L-proline ABC transporter, periplasmic glycine betaine-binding protein, putative BRA0738 88 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 23500619 Common - ATP-dependent protease La, putative BRA0892 41 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 23499841 Common - hypothetical protein BRA0074 68 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 23500574 Common - hypothetical protein BRA0844 20 COG3586 COG3586, Uncharacterized conserved protein Function unknown 161486702 Common - hypothetical protein BRA1068 15 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 23500620 Common trx-2 thioredoxin BRA0893 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 23500629 Common - oxidoreductase, FMN-binding BRA0902 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 23500494 Pathogen - hypothetical protein BRA0757 1 None None None 23500731 Common - peptide ABC transporter, ATP-binding protein BRA1008 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 23500671 Common - acetolactate synthase 2 catalytic subunit BRA0945 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 23500079 Pathogen - hypothetical protein BRA0324 2 None None None 23500803 Common - peptide ABC transporter, permease protein BRA1081 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500273 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 BRA0526 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 23500448 Common ahpC alkyl hydroperoxide reductase C BRA0708 208 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 23500463 Common gcvH glycine cleavage system protein H BRA0726 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 23500668 Common - D-galactose 1-dehydrogenase, putative BRA0941 113 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23500413 Common - hypothetical protein BRA0671 18 None None None 23500425 Common - amino acid ABC transporter, permease protein BRA0683 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 23500309 Common bfr bacterioferritin BRA0565 110 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 23499848 Common pepF oligoendopeptidase F BRA0081 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 23499971 Common - inositol monophosphatase family protein BRA0212 185 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 23499902 Common - transcriptional regulator, AraC family BRA0139 53 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23500304 Pathogen - hypothetical protein BRA0560 1 None None None 23500753 Pathogen - hypothetical protein BRA1030 1 None None None 23499866 Common - polysaccharide accessory transport protein, putative BRA0101 50 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 23500536 Common nikB nickel transporter permease NikB BRA0803 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500606 Common dcp peptidyl-dipeptidase Dcp BRA0878 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 23499773 Common iunH inosine-uridine preferring nucleoside hydrolase BRA0006 89 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 23500011 Common - hypothetical protein BRA0254 11 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 23500632 Common - oxidoreductase, putative BRA0905 95 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 23500430 Pathogen - hypothetical protein BRA0688 1 None None None 23500001 Common - hypothetical protein BRA0244 3 COG3945 COG3945, Uncharacterized conserved protein Function unknown 23500439 Common - iron compound ABC transporter, permease protein, putative BRA0699 135 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 23500787 Common ubiB ubiquinone biosynthesis protein UbiB BRA1065 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 23500890 Common - hypothetical protein BRA1177 8 None None None 23500110 Common - disulfide bond formation protein DsbB, putative BRA0357 18 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 23500557 Pathogen - hypothetical protein BRA0827 1 None None None 23500833 Common - hypothetical protein BRA1118 59 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 23500096 Pathogen - hypothetical protein BRA0343 1 None None None 23500120 Pathogen - hypothetical protein BRA0367 1 None None None 23500387 Common pcaL 3-oxoadipate enol-lactone hydrolase BRA0643 160 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 23500167 Common - exopolysaccharide biosynthesis protein Bme12 BRA0416 73 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 23500067 Pathogen - hypothetical protein BRA0312 1 None None None 23500697 Common pntB NAD(P) transhydrogenase, beta subunit BRA0971 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 23500090 Common - HlyD family secretion protein BRA0335 144 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 23500827 Common - hypothetical protein BRA1111 49 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 23500715 Common - putative sulfite oxidase subunit YedZ BRA0991 74 COG2717 COG2717, Predicted membrane protein Function unknown 23500129 Common - hypothetical protein BRA0376 2 None None None 23499835 Common - type IV secretion system protein VirB2 BRA0068 3 None None None 23499887 Pathogen - hypothetical protein BRA0124 3 None None None 23499908 Common - hypothetical protein BRA0145 200 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 23500185 Common - hypothetical protein BRA0436 14 COG4310 COG4310, Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain General function prediction only 23500232 Pathogen - hypothetical protein BRA0484 1 None None None 23500748 Common argB acetylglutamate kinase BRA1025 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 23500482 Common - sugar ABC transporter, ATP-binding protein, putative BRA0745 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 23500280 Common alkB alkylated DNA repair protein AlkB BRA0533 57 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 23500025 Common - ribitol dehydrogenase BRA0268 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 23500099 Common - transcriptional regulator, LysR family BRA0346 148 COG0583 LysR, Transcriptional regulator Transcription 23499788 Common - RNA polymerase sigma-70 factor, ECF subfamily BRA0021 68 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 23500885 Common - hypothetical protein BRA1172 114 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 23500349 Common - exoribonuclease, VacB/RNase II family BRA0605 192 COG0557 VacB, Exoribonuclease R Transcription 23500639 Common nagB glucosamine-fructose-6-phosphate aminotransferase BRA0912 233 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 23500217 Common - ABC transporter, periplasmic substrate-binding protein BRA0469 44 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 23500702 Common - hypothetical protein BRA0976 7 None None None 23499820 Pathogen - hypothetical protein BRA0053 1 None None None 23500359 Common - DNA polymerase IV BRA0615 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 23499808 Common - sensor histidine kinase BRA0041 188 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 23500775 Common - hypothetical protein BRA1053 111 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 23500850 Common flbT flagellar biosynthesis repressor FlbT BRA1135 22 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 23500352 Common - major facilitator family transporter BRA0608 95 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500265 Common - sugar ABC transporter, permease protein BRA0518 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23500336 Pathogen - hypothetical protein BRA0592 2 None None None 23500859 Common - hypothetical protein BRA1145 10 None None None 23500487 Common - sugar ABC transporter, permease protein, putative BRA0750 161 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23500381 Common pcaJ 3-oxoadipate CoA-transferase, beta subunit BRA0637 91 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 23500741 Common - hypothetical protein BRA1018 16 None None None 23500880 Common - hydrolase, haloacid dehalogenase-like family BRA1167 25 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 23500793 Pathogen - hypothetical protein BRA1071 1 None None None 23499919 Common - hypothetical protein BRA0157 15 COG3334 COG3334, Uncharacterized conserved protein Function unknown 23500503 Pathogen - hypothetical protein BRA0766 2 None None None 23500176 Common - glycosyl transferase, group 2 family protein BRA0427 93 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23500196 Common - acyl-CoA dehydrogenase BRA0447 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 23500704 Common - GGDEF domain protein BRA0979 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 23499855 Common modC molybdenum ABC transporter, ATP-binding protein BRA0090 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 23500572 Common hsdR type I restriction-modification enzyme, R subunit BRA0842 141 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 23500134 Common - membrane antigen, putative BRA0381 25 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 23500154 Common - oxidoreductase, putative BRA0402 35 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23500076 Common minC septum formation inhibitor BRA0321 76 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 23500086 Pathogen - hypothetical protein BRA0331 1 None None None 23500724 Common - hypothetical protein BRA1000 5 None None None 23499829 Common - type IV secretion system protein VirB8 BRA0062 34 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 23499873 Common - exopolysaccharide production protein, putative BRA0108 17 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 23500124 Pathogen - traC protein BRA0371 1 None None None 23500913 Pathogen - hypothetical protein BRA1201 1 None None None 23499947 Common tag DNA-3-methyladenine glycosidase I BRA0185 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 23499910 Common - hydroxypyruvate isomerase, putative BRA0147 77 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 23499965 Common - cytochrome b561, putative BRA0204 41 COG3038 CybB, Cytochrome B561 Energy production and conversion 23500191 Common - uracil-xanthine permease BRA0442 124 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 23500330 Common - hypothetical protein BRA0586 18 COG3946 VirJ, Type IV secretory pathway, VirJ component Intracellular trafficking and secretion 23500024 Common - sugar ABC transporter, permease protein BRA0267 108 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 23500567 Pathogen - hypothetical protein BRA0837 1 None None None 23500253 Pathogen - hypothetical protein BRA0506 2 None None None 23500814 Common - peptide ABC transporter, ATP-binding protein, putative BRA1094 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500210 Pathogen - hypothetical protein BRA0461 1 None None None 23499831 Common - type IV secretion system protein VirB6 BRA0064 23 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 23500847 Common flhA flagellar biosynthesis protein A BRA1132 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 23500544 Common - transcriptional regulator, GntR family BRA0813 125 COG1802 GntR, Transcriptional regulators Transcription 23500451 Common idhA myo-inositol 2-dehydrogenase BRA0711 179 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23499883 Common - transcriptional regulator, LuxR family BRA0119 70 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 23499869 Common - glycosyl transferase, WecB/TagA/CpsF family BRA0104 110 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 23500370 Common - exonuclease, putative BRA0626 161 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 23499797 Common - 3-oxoacyl-(acyl-carrier-protein) reductase, putative BRA0030 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500646 Common - oxidoreductase, molybdopterin-binding, putative BRA0919 171 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 23500171 Common - glycosyl transferase, group 1 family protein BRA0421 165 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 23499938 Pathogen - hypothetical protein BRA0176 2 None None None 23499806 Pathogen - hypothetical protein BRA0039 1 None None None 23500911 Common hemN-2 coproporphyrinogen III oxidase BRA1199 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 23500209 Common - hypothetical protein BRA0460 141 COG0628 PerM, Predicted permease General function prediction only 23500034 Common nosY nitrous-oxide reductase, nosY component BRA0278 56 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 23499817 Pathogen - hypothetical protein BRA0050 1 None None None 23500307 Common - hypothetical protein BRA0563 39 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 23500473 Pathogen - hypothetical protein BRA0736 1 None None None 23499791 Common - branched chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative BRA0024 79 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23500056 Common ftrB transcriptional activator FtrB BRA0301 82 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 23500648 Common - outer surface protein BRA0921 26 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 23500296 Pathogen - hypothetical protein BRA0549 2 None None None 23500875 Common hpcD 5-carboxymethyl-2-hydroxymuconate delta isomerase BRA1162 35 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 23500496 Common - hypothetical protein BRA0759 13 None None None 23500446 Common - major facilitator family transporter BRA0706 126 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 23500519 Common - peptide ABC transporter, permease protein BRA0785 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500390 Common pcaG protocatechuate 3,4-dioxygenase, alpha subunit BRA0646 41 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 23500878 Common - aminotransferase, class III BRA1165 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 161486704 Common flgI flagellar basal body P-ring protein BRA0156 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 23500654 Common hutC histidine utilization repressor BRA0927 115 COG2188 PhnF, Transcriptional regulators Transcription 23500622 Pathogen - hypothetical protein BRA0895 1 None None None 23500247 Common - putative monovalent cation/H+ antiporter subunit A BRA0500 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 23500279 Common - major facilitator family transporter BRA0532 186 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500861 Common - flagellin family protein BRA1147 116 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 23500400 Common ugpA glycerol-3-phosphate ABC transporter, permease protein BRA0656 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23500047 Common ubiD 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BRA0292 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 23499857 Common - hypothetical protein BRA0092 3 None None None 23500240 Pathogen - hypothetical protein BRA0493 1 None None None 23500772 Common - ABC transporter, ATP-binding/permease protein BRA1050 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 23500222 Pathogen - hypothetical protein BRA0475 1 None None None 23499785 Common - oxidoreductase, molybdopterin-binding BRA0018 128 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 23499894 Common - PAP2 family protein BRA0131 16 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 23500512 Common - hypothetical protein BRA0775 14 COG4541 COG4541, Predicted membrane protein Function unknown 23500680 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA0954 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23499973 Common - hypothetical protein BRA0214 41 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 23499978 Common mucK cis,cis-muconate transport protein MucK BRA0219 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500612 Common ohr organic hydroperoxide resistance protein BRA0885 100 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 23499956 Common groEL chaperonin GroEL BRA0195 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 23500152 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative BRA0400 149 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23500825 Common - hypothetical protein BRA1109 22 None None None 23500811 Pathogen - hypothetical protein BRA1091 1 None None None 23500358 Common - nucleoside diphosphate kinase regulator BRA0614 75 COG0782 GreA, Transcription elongation factor Transcription 23500764 Common uppP undecaprenyl pyrophosphate phosphatase BRA1042 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 23500897 Common - purple acid phosphatase family protein BRA1184 50 COG1409 Icc, Predicted phosphohydrolases General function prediction only 23500348 Common topA DNA topoisomerase I BRA0604 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 23499769 Pathogen - hypothetical protein BRA0002 1 None None None 23500509 Common - hypothetical protein BRA0772 16 None None None 23500892 Common - transcriptional regulator, GntR family BRA1179 132 COG2188 PhnF, Transcriptional regulators Transcription 23499946 Common - hypothetical protein BRA0184 88 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 23500852 Common flgL flagellar hook-associated protein FlgL BRA1137 22 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 23500391 Common - 3-carboxy-cis,cis-muconate cycloisomerase BRA0647 188 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 23499951 Common hisG ATP phosphoribosyltransferase catalytic subunit BRA0189 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 23500806 Common - 3-hydroxybutyryl-CoA dehydrogenase BRA1086 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 23500676 Pathogen - hypothetical protein BRA0950 1 None None None 23500468 Common - hypothetical protein BRA0731 42 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 23500231 Pathogen - hypothetical protein BRA0485 1 None None None 23499958 Pathogen - hypothetical protein BRA0197 1 None None None 23500105 Common guaB inositol-5-monophosphate dehydrogenase BRA0352 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 23500596 Common - transcriptional regulator, DeoR family BRA0868 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 23500838 Common znuC zinc ABC transporter, ATP-binding protein BRA1123 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 23500092 Pathogen - hypothetical protein BRA0337 1 None None None 23500163 Common - ROK family protein BRA0411 84 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 23500165 Common - transcriptional regulator, Crp/Fnr family BRA0414 87 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 23500661 Common - D-amino acid aminotransferase BRA0934 185 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 23500302 Common - IS66 family element, orf2, putative BRA0557 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500422 Pathogen - hypothetical protein BRA0680 1 None None None 23499864 Common - amidase BRA0099 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 23500713 Common - hypothetical protein BRA0989 30 COG0400 COG0400, Predicted esterase General function prediction only 23500687 Common - ABC transporter, ATP-binding protein BRA0961 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 23500691 Pathogen - hypothetical protein BRA0965 1 None None None 23500291 Common - glycosyl transferase, group 2 family protein BRA0544 71 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23500831 Common - IS3 family element, transposase orfB BRA1116 142 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500461 Pathogen - hypothetical protein BRA0724 1 None None None 23500415 Common - aldehyde dehydrogenase family protein BRA0673 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23499843 Common hemH ferrochelatase BRA0076 157 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 23500579 Pathogen - hypothetical protein BRA0850 2 COG5617 COG5617, Predicted integral membrane protein Function unknown 23500432 Common - sugar ABC transporter, permease protein, putative BRA0691 170 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23499900 Common - dolichyl-phosphate-mannose-protein mannosyltransferase family protein BRA0137 70 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 23500018 Common - NirV protein, putative BRA0261 78 COG1262 COG1262, Uncharacterized conserved protein Function unknown 23500311 Common - bmp family protein BRA0567 99 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 23499995 Common - transcriptional regulator, GntR family BRA0238 119 COG1802 GntR, Transcriptional regulators Transcription 23500759 Common - hypothetical protein BRA1037 30 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 23500820 Common - gluconolactonase, putative BRA1102 27 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 23500261 Common - hypothetical protein BRA0514 60 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 23500484 Pathogen - hypothetical protein BRA0747 1 None None None 23500263 Common - sugar ABC transporter, periplasmic sugar-binding protein BRA0516 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23500528 Common - acetyl-CoA acetyltransferase BRA0794 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 23500634 Common - hypothetical protein BRA0907 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 23500442 Common - D-amino acid oxidase family protein BRA0702 108 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 23500033 Common nosF copper ABC transporter, ATP-binding protein BRA0277 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 23500278 Common - D-aminopeptidase, putative BRA0531 52 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 23500219 Common - HlyD family secretion protein BRA0472 138 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 23500901 Common - taurine ABC transporter, permease protein BRA1188 201 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 23500677 Common - transcriptional regulator, AsnC family BRA0951 130 COG1522 Lrp, Transcriptional regulators Transcription 23500520 Common - peptide ABC transporter, periplasmic peptide-binding protein, putative BRA0786 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23500015 Common - hypothetical protein BRA0258 7 COG3319 COG3319, Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases Secondary metabolites biosynthesis, transport, and catabolism 23500010 Common - hypothetical protein BRA0253 8 None None None 23500114 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein BRA0361 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 23500160 Common - peptide ABC transporter, permease protein BRA0408 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500308 Common - hypothetical protein BRA0564 5 None None None 23500437 Common - hypothetical protein BRA0697 42 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 23499863 Common - transcriptional regulator, LysR family BRA0098 166 COG0583 LysR, Transcriptional regulator Transcription 23499907 Common - putative aldolase BRA0144 119 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 23500417 Common - iron compound ABC transporter, periplasmic iron compound-binding protein BRA0675 58 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 23500460 Common - proline dehydrogenase transcriptional activator BRA0723 164 COG1522 Lrp, Transcriptional regulators Transcription 23500539 Common - hydrolase, UxaA family BRA0806 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 23500846 Common fliR flagellar biosynthesis protein FliR BRA1131 126 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 23500375 Common - amino acid ABC transporter, periplasmic amino acid-binding protein BRA0631 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23500153 Common - alcohol dehydrogenase, zinc-containing BRA0401 208 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 23500735 Common - ABC transporter, periplasmic substrate-binding protein BRA1012 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23500783 Common - hypothetical protein BRA1061 30 COG3247 HdeD, Uncharacterized conserved protein Function unknown 23500061 Common - sugar ABC transporter, permease protein BRA0306 169 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23500126 Common - traI protein, putative BRA0373 22 None None None 23500283 Common - oligopeptide ABC transporter, permease protein BRA0536 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500142 Common - transcriptional regulator, GntR family BRA0389 120 COG1802 GntR, Transcriptional regulators Transcription 23500660 Common - hypothetical protein BRA0933 39 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 23500060 Common - sugar ABC transporter, permease protein BRA0305 180 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23500699 Common pntA NAD(P) transhydrogenase, alpha subunit BRA0973 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 23500690 Common - TPR domain protein BRA0964 158 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 23500300 Common - IS66 family element, orf4, putative BRA0555 14 None None None 23500549 Common - hypothetical protein BRA0819 51 COG1993 COG1993, Uncharacterized conserved protein Function unknown 23500427 Common - phosphatase, Ppx/GppA family BRA0685 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 23500692 Common rpsU 30S ribosomal protein S21 BRA0966 39 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 23500592 Common eryA erythritol kinase BRA0864 132 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 23500436 Common ribH riboflavin synthase subunit beta BRA0695 170 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 23500383 Common - transcriptional regulator PcaR, putative BRA0639 124 COG1414 IclR, Transcriptional regulator Transcription 23500225 Common - hypothetical protein BRA0478 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 23499875 Common - oxidoreductase, Gfo/Idh/MocA family BRA0110 159 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23500293 Common - hypothetical protein BRA0546 6 None None None 23500051 Common narI respiratory nitrate reductase, gamma subunit BRA0296 57 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 23500008 Common norD norD protein BRA0251 46 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 23500826 Common - L-fuculose phosphate aldolase, putative BRA1110 150 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 23500338 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A BRA0594 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 23500514 Common zwf glucose-6-phosphate 1-dehydrogenase BRA0778 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 23500608 Common - hypothetical protein BRA0880 22 COG5515 COG5515, Uncharacterized conserved small protein Function unknown 23500290 Common galE-2 UDP-glucose 4-epimerase BRA0543 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 23500483 Common - oxidoreductase, short chain dehydrogenase/reductase family BRA0746 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500083 Common - spermidine/putrescine ABC transporter, permease protein, putative BRA0328 212 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 23500729 Common - hypothetical protein BRA1005 118 COG0579 COG0579, Predicted dehydrogenase General function prediction only 23499950 Common hisZ ATP phosphoribosyltransferase regulatory subunit BRA0188 99 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 23500327 Common glmU UDP-N-acetylglucosamine pyrophosphorylase BRA0583 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 23499795 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA0028 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23500773 Common dapB dihydrodipicolinate reductase BRA1051 214 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 23500644 Pathogen - hypothetical protein BRA0917 1 None None None 23500505 Common - glutamine synthetase family protein BRA0768 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 23499804 Common - magnesium ion-transporting ATPase, E1-E2 family BRA0037 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 23500655 Common - N-formimino-L-glutamate deiminase BRA0928 119 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 23499793 Common - branched-chain amino acid ABC transporter, permease protein BRA0026 140 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 23500343 Common pyrB aspartate carbamoyltransferase catalytic subunit BRA0599 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 23499920 Common flgH flagellar basal body L-ring protein BRA0158 96 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 23500769 Common mepA penicillin-insensitive murein endopeptidase BRA1047 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 23500559 Pathogen - hypothetical protein BRA0829 1 None None None 23499969 Common - glutathione-regulated potassium-efflux system protein, putative BRA0210 203 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 23500471 Common - alcohol dehydrogenase, iron-containing BRA0734 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 23499927 Pathogen - hypothetical protein BRA0165 1 None None None 23500449 Common - transcriptional regulator OxyR, putative BRA0709 190 COG0583 LysR, Transcriptional regulator Transcription 23500103 Common - voltage gated chloride channel family protein BRA0350 145 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 23500685 Pathogen - hypothetical protein BRA0959 1 None None None 23500074 Pathogen - hypothetical protein BRA0319 1 None None None 23500714 Common - putative sulfite oxidase subunit YedY BRA0990 121 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 23500249 Common - putative monovalent cation/H+ antiporter subunit D BRA0502 183 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 23500552 Common - peptidoglycan-binding protein, putative BRA0822 87 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 23500617 Common leuB 3-isopropylmalate dehydrogenase BRA0890 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 23500299 Common - cell wall surface protein, putative BRA0553 73 None None None 23500243 Common mogA molybdenum cofactor biosynthesis protein BRA0496 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 23500193 Common - major facilitator family transporter BRA0444 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500226 Common - pyridine nucleotide-disulphide oxidoreductase family protein BRA0479 169 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 23500767 Common - iron-sulfur cluster-binding protein, putative BRA1045 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 23500873 Common - fumarylacetoacetate hydrolase family protein BRA1159 175 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 23500896 Common - sugar ABC transporter, ATP-binding protein, putative BRA1183 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 23500403 Common - transporter, TrkA family BRA0659 107 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 23500722 Common - hypothetical protein BRA0998 9 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 23500395 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA0651 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23500271 Common - 2-oxoisovalerate dehydrogenase E1 component, alpha subunit BRA0524 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 23500149 Common - shikimate dehydrogenase family protein BRA0397 203 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 23500577 Pathogen - hypothetical protein BRA0848 1 None None None 23500452 Common - SIS domain protein BRA0712 89 COG1737 RpiR, Transcriptional regulators Transcription 23499810 Common - response regulator BRA0043 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 23499884 Common - hypothetical protein BRA0120 9 None None None 23499828 Common - type IV secretion system protein VirB9 BRA0061 51 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 23500204 Common - hypothetical protein BRA0455 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 23500615 Common - major facilitator family transporter BRA0888 127 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500625 Common - hypothetical protein BRA0898 46 COG2346 COG2346, Truncated hemoglobins General function prediction only 23500564 Pathogen - hypothetical protein BRA0834 1 None None None 23500770 Common mgsA methylglyoxal synthase BRA1048 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 23500757 Common def peptide deformylase BRA1035 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 23500039 Common - ABC transporter, periplasmic binding protein, putative BRA0284 58 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 23499936 Common cycA cytochrome c2 BRA0174 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 23500828 Common - hypothetical protein BRA1112 12 None None None 23500136 Common - iron permease, FTR1 family BRA0383 52 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 23500372 Common - transcriptional regulator, AraC family BRA0628 121 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23499944 Common glcF glycolate oxidase, iron-sulfur subunit BRA0182 179 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 23500640 Common - transcriptional regulator, GntR family BRA0913 143 COG2188 PhnF, Transcriptional regulators Transcription 23499777 Common - lipoprotein, Bmp family BRA0010 102 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 23500804 Common - transcriptional regulator, IclR family BRA1082 109 COG1414 IclR, Transcriptional regulator Transcription 23500054 Common narG respiratory nitrate reductase, alpha subunit BRA0299 111 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 23499962 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase BRA0201 211 COG0196 RibF, FAD synthase Coenzyme metabolism 23500594 Common eryC D-erythrulose-1-phosphate dehydrogenase BRA0866 8 None None None 23499823 Common - amino acid permease family protein BRA0056 139 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 23499802 Pathogen - hypothetical protein BRA0035 1 None None None 23500588 Common rbsA-3 ribose ABC transporter, ATP-binding protein BRA0860 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23500259 Common ybgT ybgT protein BRA0512 10 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 23500836 Pathogen - hypothetical protein BRA1121 1 None None None 23500848 Common fliQ flagellar biosynthesis protein FliQ BRA1133 46 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 23499929 Common - hypothetical protein BRA0167 32 COG3777 COG3777, Uncharacterized conserved protein Function unknown 23500527 Common fadB fatty oxidation complex, alpha subunit BRA0793 176 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 23499922 Common fliP flagellar biosynthesis protein FliP BRA0160 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 23500657 Common hutH histidine ammonia-lyase BRA0930 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 23500319 Common - hypothetical protein BRA0575 17 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 23500131 Common - hypothetical protein BRA0378 10 None None None 23499839 Common - hypothetical protein BRA0072 17 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 23499916 Common flgG flagellar basal body rod protein FlgG BRA0154 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 23500752 Common - hypothetical protein BRA1029 34 COG3672 COG3672, Predicted periplasmic protein Function unknown 23500912 Pathogen - hypothetical protein BRA1200 1 None None None 23500700 Common - hypothetical protein BRA0974 6 None None None 23500863 Common - hypothetical protein BRA1149 30 COG3268 COG3268, Uncharacterized conserved protein Function unknown 23500881 Common - hypothetical protein BRA1168 29 COG5441 COG5441, Uncharacterized conserved protein Function unknown 23499985 Common - ThiJ/PfpI family protein BRA0227 80 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 23500570 Common hsdM type I restriction-modification system, M subunit BRA0840 163 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 23499770 Pathogen - hypothetical protein BRA0003 1 None None None 23500799 Common - CAIB/BAIF family protein BRA1077 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 23500854 Common flgE flagellar hook protein FlgE BRA1139 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 23500199 Common - acetyl-CoA synthetase, putative BRA0450 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 23500174 Common - acetyltransferase, CysE/LacA/LpxA/NodL family BRA0424 111 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 23499937 Common - hypothetical protein BRA0175 19 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 23500866 Common xylH D-xylose ABC transporter, permease protein BRA1152 111 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 23500706 Common - 2-deoxy-d-gluconate 3-dehydrogenase, putative BRA0981 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500841 Pathogen - hypothetical protein BRA1126 2 None None None 23500324 Common - hypothetical protein BRA0580 39 COG2938 COG2938, Uncharacterized conserved protein Function unknown 23500906 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative BRA1193 138 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23499850 Common - hypothetical protein BRA0083 63 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 23500356 Common divK polar differentiation response regulator BRA0612 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 23500190 Pathogen - hypothetical protein BRA0441 1 None None None 23500746 Common - putative inner membrane protein translocase component YidC BRA1023 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 23500914 Common repA replication protein RepA BRA1202 202 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 23499861 Common - hypothetical protein BRA0096 36 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 23500420 Common - iron compound ABC transporter, ATP-binding protein BRA0678 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 23499814 Pathogen - hypothetical protein BRA0047 1 None None None 23500213 Common - ABC transporter, permease protein BRA0465 127 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 23500238 Common bioF 8-amino-7-oxononanoate synthase BRA0491 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 23500023 Common - sugar ABC transporter, ATP-binding protein, putative BRA0266 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23500813 Common - peptide ABC transporter, permease protein, putative BRA1093 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500500 Common - glutamate--cysteine ligase BRA0763 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 23499859 Pathogen - hypothetical protein BRA0093 1 None None None 23500459 Pathogen - hypothetical protein BRA0721 1 None None None 23500285 Common - oligopeptide ABC transporter, periplasmic oligopeptide-binding protein BRA0538 209 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 23500169 Common - fucose synthetase family protein BRA0418 208 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 23500063 Common - hypothetical protein BRA0308 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 23500316 Common pcs phosphatidylcholine synthase BRA0572 28 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 23500599 Common fbaA fructose-1,6-bisphosphate aldolase BRA0871 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 23500695 Common - hydrolase, haloacid dehalogenase-like family BRA0969 168 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 23500636 Common purU formyltetrahydrofolate deformylase BRA0909 217 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 23500532 Common - acyl-CoA dehydrogenase family protein BRA0799 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 23500150 Common - oxidoreductase, GMC family BRA0398 97 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 23499877 Common - spermidine/putrescine ABC transporter, ATP-binding protein BRA0112 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 23500720 Common rbsB-3 ribose ABC transporter, periplasmic D-ribose-binding protein BRA0996 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23500727 Common - hypothetical protein BRA1003 11 None None None 23500269 Pathogen - hypothetical protein BRA0522 1 None None None 23500750 Common - conserved hypothetical protein TIGR00730, putative BRA1027 106 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 23499914 Common flgC flagellar basal body rod protein FlgC BRA0152 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 23500295 Common - hypothetical protein BRA0548 6 None None None 23500575 Pathogen - IS711, transposase orfA BRA0846 1 None None None 23500424 Common fliY amino acid ABC transporter, periplasmic amino acid-binding protein BRA0682 190 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23500013 Common - hypothetical protein BRA0256 16 None None None 23500733 Common - peptide ABC transporter, permease protein BRA1010 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500410 Pathogen - hypothetical protein BRA0668 1 None None None 23500108 Common katA catalase BRA0355 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 23500694 Common - nodulation protein N, putative BRA0968 79 COG2030 MaoC, Acyl dehydratase Lipid metabolism 23500550 Common - transcriptional regulator, MerR family BRA0820 115 COG0789 SoxR, Predicted transcriptional regulators Transcription 23500601 Pathogen - hypothetical protein BRA0873 1 None None None 23500306 Common rirA iron-responsive transcriptional regulator BRA0562 102 COG1959 COG1959, Predicted transcriptional regulator Transcription 23500333 Common lipB lipoyltransferase BRA0589 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 23499784 Common - enterobactin synthetase, component F, putative BRA0017 55 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 23500824 Common - glutamate-1-semialdehyde 2,1-aminomutase, putative BRA1108 202 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 23500112 Common - hypothetical protein BRA0359 67 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 23500377 Common - hypothetical protein BRA0633 38 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 23499905 Pathogen - hypothetical protein BRA0142 1 None None None 23500419 Common - iron compound ABC transporter, permease protein BRA0677 49 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 23500444 Common - multicopper oxidase BRA0704 124 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 23500642 Common - secretion protein, putative BRA0915 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 23500101 Common - phosphoglucomutase, putative BRA0348 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 23500524 Common lysK lysyl-tRNA synthetase BRA0790 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 23500080 Common - hypothetical protein BRA0325 18 None None None 23500832 Pathogen - hypothetical protein BRA1117 1 None None None 23500397 Common ade adenine deaminase BRA0653 77 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 23500879 Common - hypothetical protein BRA1166 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 23499825 Common - lipoprotein, putative BRA0058 8 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 23500140 Pathogen - hypothetical protein BRA0387 1 None None None 23500707 Common - glutamine amidotransferase, class I BRA0982 115 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 23500447 Common ahpD alkyl hydroperoxide reductase D BRA0707 27 COG2128 COG2128, Uncharacterized conserved protein Function unknown 23500220 Common - osmolarity sensor protein EnvZ, putative BRA0473 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 23500547 Common - crcB family protein BRA0817 39 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 23499781 Common entB isochorismatase BRA0014 64 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 23500362 Common - GGDEF domain protein BRA0618 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 23500275 Common - SurF1 family protein BRA0528 59 COG3346 COG3346, Uncharacterized conserved protein Function unknown 23500245 Pathogen - hypothetical protein BRA0498 1 None None None 23500340 Common - metal-dependent hydrolase BRA0596 86 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 23500250 Common - putative monovalent cation/H+ antiporter subunit E BRA0503 66 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 23500043 Pathogen - hypothetical protein BRA0288 1 None None None 23500894 Common - sugar ABC transporter, permease protein, putative BRA1181 134 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23500782 Common cls cardiolipin synthase BRA1060 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 23499991 Common - ApbE family protein BRA0234 142 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 23500498 Common - transcriptional regulator, MarR family BRA0761 122 COG1846 MarR, Transcriptional regulators Transcription 23500872 Common hpaH 2-keto-4-pentenoate hydratase BRA1158 63 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 23500899 Common - taurine ABC transporter, taurine-binding protein BRA1186 124 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 23500405 Common - uracil-xanthine permease, putative BRA0661 138 COG2252 COG2252, Permeases General function prediction only 23500367 Pathogen - hypothetical protein BRA0623 1 None None None 23500516 Common folD FolD bifunctional protein BRA0781 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 23500779 Common - hypothetical protein BRA1057 9 COG3714 COG3714, Predicted membrane protein Function unknown 23500856 Common - hypothetical protein BRA1141 43 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 23499952 Common - hypothetical protein BRA0191 76 COG2259 COG2259, Predicted membrane protein Function unknown 23500584 Pathogen - hypothetical protein BRA0856 1 None None None 23500478 Pathogen - hypothetical protein BRA0741 1 None None None 23500228 Common - glyoxalase, putative BRA0481 46 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 23500339 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C BRA0595 165 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 23500286 Pathogen - hypothetical protein BRA0539 1 None None None 23499897 Pathogen - hypothetical protein BRA0134 1 COG2246 COG2246, Predicted membrane protein Function unknown 23499775 Common - ABC transporter, permease protein, putative BRA0008 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 23500325 Common recG ATP-dependent DNA helicase RecG BRA0581 217 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 23500159 Common - peptide ABC transporter, permease protein BRA0407 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23499981 Common - enoyl-CoA hydratase BRA0222 189 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 23500276 Pathogen - hypothetical protein BRA0529 1 None None None 23500659 Common hutU urocanate hydratase BRA0932 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 23499960 Common - hydrolase, haloacid dehalogenase-like family BRA0199 51 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 23499800 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 BRA0033 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 23500683 Common - branched-chain amino acid ABC transporter, permease protein BRA0957 59 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 23499812 Common - inositol monophosphatase family protein BRA0045 178 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 23500257 Common cydA cytochrome d ubiquinol oxidase, subunit I BRA0510 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 23499899 Common - hypothetical protein BRA0136 32 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 23500603 Common - GTP-binding protein TypA BRA0875 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 23500586 Common rbsB-2 ribose ABC transporter, periplasmic D-ribose-binding protein BRA0858 97 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23500314 Common - ABC transporter, ATP-binding protein BRA0570 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 23500081 Common - spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein, putative BRA0326 94 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 23500581 Common - epimerase/dehydratase family protein, putative BRA0852 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 23499941 Pathogen - hypothetical protein BRA0179 1 None None None 23499974 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase BRA0215 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 23500834 Common - RrF2 family protein BRA1119 153 COG1959 COG1959, Predicted transcriptional regulator Transcription 23500457 Common - ABC transporter, permease protein BRA0719 215 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 23500195 Common - methionine sulfoxide reductase B BRA0446 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 23500450 Common - hypothetical protein BRA0710 8 COG3177 COG3177, Uncharacterized conserved protein Function unknown 23500235 Common - 3-oxoacyl-(acyl carrier protein) synthase II BRA0488 199 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 23500455 Common - inositol monophosphatase family protein BRA0717 205 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 23499790 Common - transcriptional regulator, GntR family BRA0023 153 COG2186 FadR, Transcriptional regulators Transcription 23500021 Pathogen - hypothetical protein BRA0264 1 None None None 23499852 Pathogen - hypothetical protein BRA0087 1 None None None 23500031 Common nosZ nitrous-oxide reductase BRA0275 40 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 23499886 Common - flagellar motor switch protein FliN, putative BRA0123 124 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 23500183 Common - hypothetical protein BRA0434 10 None None None 23500374 Common - amino acid dehydrogenase, putative BRA0630 124 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 23500037 Common nnrR transcriptional regulator NnrR BRA0281 173 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 23500562 Pathogen - hypothetical protein BRA0832 1 None None None 23500780 Common - aldehyde dehydrogenase family protein BRA1058 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23500819 Common - oligopeptide ABC transporter, ATP-binding protein, putative BRA1101 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500843 Common - hypothetical protein BRA1128 10 None None None 23500904 Pathogen - hypothetical protein BRA1191 1 None None None 23500188 Common - nucleotidyltransferase family protein BRA0439 147 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 23499934 Pathogen - hypothetical protein BRA0172 1 None None None 23500491 Common - iron compound ABC transporter, ATP-binding protein BRA0754 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 23500744 Common rpmH 50S ribosomal protein L34 BRA1021 189 None None None 23500215 Common - taurine ABC transporter, permease protein, putative BRA0467 196 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 23500071 Common nrdE ribonucleotide-diphosphate reductase subunit alpha BRA0316 216 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 23500132 Common - DNA-damage-inducible protein J, putative BRA0379 30 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 23500138 Common xfp putative phosphoketolase BRA0385 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 23500046 Common - hypothetical protein BRA0291 14 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 23500627 Common rocF arginase BRA0900 140 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 23500883 Common - amino acid permease family protein BRA1170 127 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 23500236 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase BRA0489 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 23500801 Common - peptide ABC transporter, ATP-binding protein BRA1079 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500666 Common dgoK 2-dehydro-3-deoxygalactonokinase BRA0939 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 23500094 Common hdeA stress-response and acid-resistance protein BRA0341 5 None None None 23500506 Common - hypothetical protein BRA0769 33 None None None 23500739 Pathogen - hypothetical protein BRA1016 1 None None None 23500868 Common - transcriptional regulator, AraC family BRA1154 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23499987 Pathogen - hypothetical protein BRA0230 1 None None None 23500910 Common cadA-2 cadmium-translocating P-type ATPase BRA1198 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 23500172 Common - glycosyl transferase, group 1 family protein BRA0422 189 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 23500354 Common pleD response regulator PleD BRA0610 223 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 23499771 Pathogen - hypothetical protein BRA0004 1 None None None 23500797 Pathogen - hypothetical protein BRA1075 1 None None None 23499844 Common omp10 lipoprotein Omp10 BRA0077 7 None None None 23500200 Common - transcriptional regulator, AraC family BRA0451 82 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23500146 Common - branched-chain amino acid ABC transporter, permease protein BRA0393 160 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 23500322 Common - fosfomycin resistance family protein BRA0578 12 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 23500347 Pathogen - hypothetical protein BRA0603 1 None None None 23500508 Common - transcriptional regulator, MarR family BRA0771 17 COG1846 MarR, Transcriptional regulators Transcription 23500267 Common - oxidoreductase, Gfo/Idh/MocA family BRA0520 153 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23500791 Common msrA methionine sulfoxide reductase A BRA1069 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 23500518 Common - peptide ABC transporter, permease protein BRA0784 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23499846 Common - hypothetical protein BRA0079 77 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 23499955 Pathogen - hypothetical protein BRA0194 1 None None None 23500246 Common - hypothetical protein BRA0499 31 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 23500812 Common - peptide ABC transporter, permease protein, putative BRA1092 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500649 Common - alanine catabolic operon transcriptional regulator, putative BRA0922 158 COG1522 Lrp, Transcriptional regulators Transcription 23500842 Common - hypothetical protein BRA1127 11 None None None 23500732 Common - peptide ABC transporter, ATP-binding protein BRA1009 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23499889 Common motA flagellar motor protein MotA BRA0126 113 COG1291 MotA, Flagellar motor component Cell motility and secretion 23500679 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative BRA0953 92 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23500709 Common - transcriptional regulator, putative BRA0984 128 COG1609 PurR, Transcriptional regulators Transcription 23500511 Common - AzlC family protein BRA0774 106 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 23500406 Pathogen - hypothetical protein BRA0662 1 None None None 23499786 Common - HupC/HyaC/HydC family protein BRA0019 39 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 23500613 Common - transcriptional regulator, MarR family BRA0886 84 COG1846 MarR, Transcriptional regulators Transcription 23499826 Common - type IV secretion system protein VirB11 BRA0059 171 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 23500725 Common - extradiol ring-cleaving dioxygenase, putative BRA1001 45 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 23500681 Common - branched-chain amino acid ABC transporter, ATP-binding protein LivF, putative BRA0955 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23500638 Common nagA N-acetylglucosamine-6-phosphate deacetylase BRA0911 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 23500765 Pathogen - hypothetical protein BRA1043 1 None None None 23500877 Common - hypothetical protein BRA1164 59 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 23500445 Pathogen - hypothetical protein BRA0705 2 None None None 23500493 Common - iron compound ABC transporter, periplasmic iron compound-binding protein BRA0756 83 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 23500392 Common - amino acid ABC transporter, periplasmic amino-acid binding protein BRA0648 108 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23500830 Common - IS3 family element, transposase orfA BRA1115 73 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500561 Common - 2-nitropropane dioxygenase family protein BRA0831 75 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 23500870 Common - 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative BRA1156 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 161486703 Common upp uracil phosphoribosyltransferase BRA1067 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 23499880 Common - ABC transporter, periplasmic substrate-binding protein BRA0115 58 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 23500032 Common nosD copper ABC transporter, periplasmic copper-binding protein BRA0276 51 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 23500651 Common dadA D-amino acid dehydrogenase small subunit BRA0924 148 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 23500019 Common - transcriptional regulator, Crp/Fnr family BRA0262 174 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 23500379 Common - twin-arginine translocation signal domain protein BRA0635 114 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 23500118 Pathogen - hypothetical protein BRA0365 1 None None None 23500760 Common - hypothetical protein BRA1038 63 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 23500688 Common - ABC transporter, permease protein BRA0962 188 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 23500201 Pathogen - hypothetical protein BRA0452 1 None None None 23499867 Pathogen - hypothetical protein BRA0102 1 None None None 23500665 Common - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase BRA0938 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 23500743 Pathogen - hypothetical protein BRA1020 1 None None None 23499895 Pathogen - hypothetical protein BRA0132 1 None None None 23500014 Common - hypothetical protein BRA0257 40 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 23499903 Pathogen - hypothetical protein BRA0140 1 None None None 23500412 Common - putative FAD-binding dehydrogenase BRA0670 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 23500631 Common - tex protein, putative BRA0904 141 COG2183 Tex, Transcriptional accessory protein Transcription 23500106 Common - cytochrome c family protein BRA0353 37 COG3258 COG3258, Cytochrome c Energy production and conversion 23499849 Common - sigma-54 dependent DNA-binding response regulator BRA0082 217 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 23500066 Common - transporter, putative BRA0311 117 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500535 Common nikC nickel transporter permease NikC BRA0802 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23500421 Common - hypothetical protein BRA0679 24 COG5631 COG5631, Predicted transcription regulator, contains HTH domain (MarR family) Transcription 23500386 Common pcaQ transcriptional regulator PcaQ BRA0642 188 COG0583 LysR, Transcriptional regulator Transcription 23500621 Common - hypothetical protein BRA0894 30 COG3760 COG3760, Uncharacterized conserved protein Function unknown 23500821 Common - amidase BRA1103 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 23500058 Pathogen - hypothetical protein BRA0303 1 None None None 23500467 Common - transcriptional regulator, putative BRA0730 75 COG1737 RpiR, Transcriptional regulators Transcription 23500128 Common - hypothetical protein BRA0375 16 None None None 23500529 Common - acyl-CoA dehydrogenase family protein BRA0795 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 23500009 Common - hypothetical protein BRA0252 26 COG4309 COG4309, Uncharacterized conserved protein Function unknown 23499909 Common - transcriptional regulator, DeoR family BRA0146 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 23500807 Common - enoyl-CoA hydratase BRA1087 186 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 23500111 Common - sun protein, putative BRA0358 206 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 23500004 Pathogen norF norF protein BRA0247 2 None None None 23500862 Common - outer membrane autotransporter BRA1148 93 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 23500365 Common - endonuclease V BRA0621 6 None None None 23500301 Common - IS66 family element, orf3, putative BRA0556 59 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500166 Common - transcriptional regulator, LuxR family BRA0415 154 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 23500556 Common - ATP-dependent RNA helicase, DEAD/DEAH box family BRA0826 187 COG1201 Lhr, Lhr-like helicases General function prediction only 23499807 Common - MgtC family protein BRA0040 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 23500717 Common rbsC-4 ribose ABC transporter, permease protein BRA0993 109 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 23500541 Common - ABC transporter, ATP-binding protein BRA0809 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 23500388 Common pcaC 4-carboxymuconolactone decarboxylase BRA0644 89 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 23500087 Common - hypothetical protein BRA0332 2 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 23499989 Common - hypothetical protein BRA0232 14 None None None 23500100 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase BRA0347 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 23500216 Common - ABC transporter, ATP-binding protein BRA0468 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 23499980 Common - transcriptional regulator, IclR family BRA0221 97 COG1414 IclR, Transcriptional regulator Transcription 23499854 Common modB molybdate ABC transporter permease protein BRA0089 181 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 23499966 Common - cytidine and deoxycytidylate deaminase family protein BRA0205 213 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 23500796 Common - transcriptional regulator, GntR family BRA1074 123 COG1802 GntR, Transcriptional regulators Transcription 23500364 Pathogen - hypothetical protein BRA0620 1 None None None 23500179 Common - glycosyl transferase, group 2 family protein BRA0430 171 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23500135 Common - hypothetical protein BRA0382 20 None None None 23499976 Common - hypothetical protein BRA0217 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 23500858 Common motB flagellar motor protein MotB BRA1144 116 COG1360 MotB, Flagellar motor protein Cell motility and secretion 23500756 Common fmt methionyl-tRNA formyltransferase BRA1034 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 23500777 Common - universal stress protein family BRA1055 97 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 23500888 Common - branched chain amino acid ABC transporter, ATP-binding/permease protein BRA1175 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23500123 Pathogen - hypothetical protein BRA0370 1 None None None 23499992 Common - GAF/GGDEF domain protein BRA0235 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 23500028 Common - hypothetical protein BRA0271 25 None None None 23500464 Common gcvT glycine cleavage system T protein BRA0727 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 23500044 Common - protease, putative BRA0289 46 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 23500426 Common - amino acid ABC transporter, ATP-binding protein BRA0684 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 23500701 Pathogen - hypothetical protein BRA0975 1 None None None 23500125 Common - traJ protein BRA0372 14 None None None 23499832 Common - type IV secretion system protein VirB5 BRA0065 19 None None None 23499798 Common - oxidoreductase, short chain dehydrogenase/reductase family BRA0031 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23499932 Common - cytochrome b561, putative BRA0170 9 COG3038 CybB, Cytochrome B561 Energy production and conversion 23500523 Common - hypothetical protein BRA0789 15 None None None 23499896 Pathogen - hypothetical protein BRA0133 1 None None None 23500568 Pathogen - hypothetical protein BRA0838 1 None None None 23500186 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase BRA0437 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 23499948 Common - transporter, LysE family BRA0186 112 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 23500189 Common - hypothetical protein BRA0440 15 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 23500332 Common - sensory box protein BRA0588 130 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 23500078 Common minE cell division topological specificity factor MinE BRA0323 73 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 23500208 Common - transcriptional regulator, GntR family BRA0459 137 COG1802 GntR, Transcriptional regulators Transcription 23500670 Common - hypothetical protein BRA0943 17 None None None 23500674 Common - amino acid ABC transporter, periplasmic amino acid-binding protein BRA0948 111 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23500517 Common proC pyrroline-5-carboxylate reductase BRA0782 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 23499957 Common groES co-chaperonin GroES BRA0196 212 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 23500488 Common - endoribonuclease L-PSP, putative BRA0751 184 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 23500730 Common - DNA polymerase III subunit epsilon BRA1006 63 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 23500546 Common - HlyD family secretion protein BRA0816 164 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 23500310 Common - conserved hypothetical protein TIGR01125 BRA0566 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 23500808 Common - acyl-CoA dehydrogenase BRA1088 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 23500590 Pathogen - hypothetical protein BRA0862 1 None None None 23500035 Common - protein disulfide isomerase NosL, putative BRA0279 28 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 23500170 Common - GDP-mannose 4,6-dehydratase Bme9 BRA0419 219 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 23499824 Common - hypothetical protein BRA0057 28 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 23499879 Common - spermidine/putrescine ABC transporter, permease protein, putative BRA0114 143 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 23500317 Common ubiH 2-octaprenyl-6-methoxyphenyl hydroxylase BRA0573 123 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 23499926 Pathogen - hypothetical protein BRA0164 1 None None None 23500869 Common - aldehyde dehydrogenase family protein BRA1155 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23500229 Pathogen - hypothetical protein BRA0482 1 None None None 23500585 Common - transcriptional regulator, DeoR family BRA0857 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 23500233 Common metA homoserine O-succinyltransferase BRA0486 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 23500844 Common - hypothetical protein BRA1129 12 None None None 23499870 Common - hypothetical protein BRA0105 38 None None None 23500898 Common - sulfatase BRA1185 96 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 23500048 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BRA0293 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 23499856 Common - acetyltransferase, GNAT family BRA0091 71 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 23500401 Common ugpE glycerol-3-phosphate ABC transporter, permease protein BRA0657 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23500465 Common - hypothetical protein BRA0728 8 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 23500399 Common ugpB glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein BRA0655 108 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23499792 Common - branched-chain amino acid ABC transporter, permease protein BRA0025 144 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 23500297 Common - transcriptional regulator, AraC family BRA0550 32 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23500223 Common - hypothetical protein BRA0476 2 None None None 23500653 Common - beta alanine--pyruvate transaminase BRA0926 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 23500737 Common - aldehyde dehydrogenase family protein BRA1014 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23500876 Common - transcriptional regulator, MarR family BRA1163 86 COG1846 MarR, Transcriptional regulators Transcription 23500144 Common - alcohol dehydrogenase, zinc-containing BRA0391 177 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 23499921 Common - flagellar protein FliL, putative BRA0159 11 None None None 23500605 Pathogen - hypothetical protein BRA0877 1 None None None 23500723 Common - nosA protein, putative BRA0999 83 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 23500543 Common - glucuronate isomerase BRA0812 60 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 23500891 Common - hypothetical protein BRA1178 62 COG0730 COG0730, Predicted permeases General function prediction only 23500272 Common - 2-oxoisovalerate dehydrogenase, E1 component, beta subunit BRA0525 215 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 23499998 Pathogen - hypothetical protein BRA0241 1 None None None 23499893 Common - hypothetical protein BRA0130 6 None None None 23500611 Common - hypothetical protein BRA0884 48 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 23499840 Common - sugar isomerase, KpsF/GutQ BRA0073 168 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 23499979 Common - acyl-CoA dehydrogenase BRA0220 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 23500091 Common - hypothetical protein BRA0336 26 COG4803 COG4803, Predicted membrane protein Function unknown 23500537 Common - nickel ABC transporter, nickel-binding protein, putative BRA0804 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23500513 Common - 3-ketoacyl-(acyl-carrier-protein) reductase BRA0777 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500155 Common - oxidoreductase, Gfo/Idh/MocA family BRA0403 186 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23500771 Common glk glucokinase BRA1049 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 23500571 Common hsdS type I restriction-modification system, S subunit BRA0841 45 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 23500554 Common - hypothetical protein BRA0824 28 None None None 23500164 Pathogen - hypothetical protein BRA0413 2 None None None 23500763 Common - NADH-ubiquinone oxidoreductase, putative BRA1041 140 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 23500431 Pathogen - hypothetical protein BRA0689 1 None None None 23500068 Pathogen - hypothetical protein BRA0313 1 None None None 23500462 Common gcvP glycine dehydrogenase BRA0725 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 23500662 Common - sugar ABC transporter, permease protein BRA0935 116 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 23500623 Pathogen - hypothetical protein BRA0896 1 None None None 23500905 Common - transcriptional regulator, AraC family BRA1192 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23500006 Common norB nitric-oxide reductase, large subunit BRA0249 104 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 23500805 Common - ABC transporter, periplasmic substrate-binding protein, putative BRA1084 204 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23499809 Common - DNA-binding response regulator, LuxR family BRA0042 213 COG4566 TtrR, Response regulator Signal transduction mechanisms 23500698 Common pntAB NAD(P) transhydrogenase, alpha2 subunit BRA0972 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 23500476 Common - glycine betaine/L-proline ABC transporter, permease protein, putative BRA0739 215 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 23500281 Common - ABC transporter, ATP-binding protein BRA0534 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 23500162 Common - transcriptional regulator, GntR family BRA0410 129 COG2186 FadR, Transcriptional regulators Transcription 23499970 Common pmbA pmbA protein BRA0211 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 23500839 Common znuB zinc ABC transporter, permease protein BRA1124 197 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 23500597 Common tpiA triosephosphate isomerase BRA0869 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 23499959 Pathogen - hypothetical protein BRA0198 1 None None None 23500749 Common - hydrolase, haloacid dehalogenase-like family BRA1026 46 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 23500864 Common xylF D-xylose ABC transporter, periplasmic D-xylose-binding protein BRA1150 86 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 23500742 Common - hypothetical protein BRA1019 123 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 23500675 Common - hypothetical protein BRA0949 238 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 23500481 Common - transcriptional regulator, RpiR family BRA0744 84 COG1737 RpiR, Transcriptional regulators Transcription 23500012 Common - hypothetical protein BRA0255 151 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 23500104 Pathogen - hypothetical protein BRA0351 1 None None None 23500633 Common - transcriptional regulator, LysR family BRA0906 180 COG0583 LysR, Transcriptional regulator Transcription 23500440 Common - iron compound ABC transporter, periplasmic iron compound-binding protein, putative BRA0700 106 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 23500116 Common - DNA-binding protein, putative BRA0363 19 COG3311 AlpA, Predicted transcriptional regulator Transcription 23500055 Common narK nitrite extrusion protein BRA0300 101 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 23500810 Common - peptide ABC transporter, periplasmic peptide-binding protein BRA1090 194 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23500434 Common - sugar ABC transporter, periplasmic sugar-binding protein BRA0693 61 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23499865 Common - decarboxylase, ornithine/DAP/arginine decarboxylase family 2 BRA0100 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 23499901 Pathogen - hypothetical protein BRA0138 1 None None None 23500394 Common - branched-chain amino acid ABC transporter, permease protein, BRA0650 89 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 23500069 Common nrdH glutaredoxin-like protein nrdH BRA0314 38 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 23500414 Pathogen - hypothetical protein BRA0672 1 None None None 23500578 Pathogen - hypothetical protein BRA0849 2 None None None 23500762 Pathogen - hypothetical protein BRA1040 1 None None None 23500202 Common serA-2 D-3-phosphoglycerate dehydrogenase BRA0453 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 23500017 Common - copper-containing nitrite reductase BRA0260 47 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 23499996 Common - dihydrodipicolinate synthase family protein BRA0239 180 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 23500312 Common - ABC transporter, permease protein BRA0568 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 23500495 Common - HlyD family secretion protein BRA0758 161 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 23500408 Common - hypothetical protein BRA0665 3 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 23500663 Common - sugar ABC transporter, ATP-binding protein BRA0936 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23500389 Common pcaH protocatechuate 3,4-dioxygenase, beta subunit BRA0645 51 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 23500042 Pathogen - hypothetical protein BRA0287 1 None None None 23500121 Common - trbJ protein BRA0368 31 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 23500747 Common - GTPase EngB BRA1024 180 COG0218 COG0218, Predicted GTPase General function prediction only 23499913 Common flgB flagellar basal body rod protein FlgB BRA0151 12 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 23500026 Common - ribitol kinase BRA0269 175 COG1069 AraB, Ribulose kinase Energy production and conversion 23500288 Pathogen - hypothetical protein BRA0541 1 None None None 23500049 Common - hypothetical protein BRA0294 19 None None None 23499821 Common gltB glutamate synthase, large subunit BRA0054 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 23500886 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative BRA1173 19 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23500815 Common - transcriptional regulator, putative BRA1096 120 COG1802 GntR, Transcriptional regulators Transcription 23500716 Common - hypothetical protein BRA0992 145 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 23500127 Pathogen - hypothetical protein BRA0374 2 None None None 23500254 Common - hypothetical protein BRA0507 37 COG1510 COG1510, Predicted transcriptional regulators Transcription 23500851 Common flaF flagellar biosynthesis regulatory protein FlaF BRA1136 14 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 23499830 Pathogen - type IV secretion system protein VirB7 BRA0063 1 None None None 23499994 Pathogen - hypothetical protein BRA0237 1 None None None 23500335 Common parE DNA topoisomerase IV subunit B BRA0591 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 23500583 Common - hypothetical protein BRA0855 59 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 23500502 Common - transcriptional regulator, LysR family BRA0765 188 COG0583 LysR, Transcriptional regulator Transcription 23500794 Common - IS3 family element, transposase orfB BRA1072 142 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 23500538 Common - nickel responsive regulator BRA0805 63 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 23500719 Common rbsA-4 ribose ABC transporter, ATP-binding protein BRA0995 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23500177 Common - undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase, putative BRA0428 99 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 23500197 Common phbA-2 acetyl-CoA acetyltransferase BRA0448 179 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 23500573 Common - hypothetical protein BRA0843 150 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 23499834 Common - type IV secretion system protein VirB3 BRA0067 6 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 23500776 Common - nitroreductase family protein BRA1054 82 COG0778 NfnB, Nitroreductase Energy production and conversion 23500264 Pathogen - hypothetical protein BRA0517 1 None None None 23499939 Common - transcriptional regulator, GntR family BRA0177 144 COG2186 FadR, Transcriptional regulators Transcription 23500754 Common dapE succinyl-diaminopimelate desuccinylase BRA1031 214 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 23500351 Common - MutT/nudix family protein BRA0607 25 None None None 23499982 Common - 3-hydroxybutyryl-CoA dehydrogenase BRA0223 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 23500740 Common - transporter, putative BRA1017 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23500341 Common - conserved hypothetical protein TIGR00250 BRA0597 168 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 23500115 Common - site-specific recombinase, phage integrase family BRA0362 114 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23500382 Common pcaI 3-oxoadipate CoA-transferase, alpha subunit BRA0638 100 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 23499779 Common - enterobactin synthetase, component D, putative BRA0012 35 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 23500329 Common - hypothetical protein BRA0585 76 COG2898 COG2898, Uncharacterized conserved protein Function unknown 23499796 Common - glyoxalase family protein BRA0029 8 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 23499816 Pathogen - hypothetical protein BRA0049 1 None None None 23500098 Pathogen - hypothetical protein BRA0345 1 None None None 23499945 Common - oxidoreductase, aldo/keto reductase family BRA0183 187 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 23499964 Common - hypothetical protein BRA0203 8 None None None 23500736 Common - 3-ketoacyl-(acyl-carrier-protein) reductase BRA1013 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23500785 Common prfC peptide chain release factor 3 BRA1063 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 23500600 Common fbp fructose-1,6-bisphosphatase BRA0872 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 23500085 Pathogen - hypothetical protein BRA0330 1 None None None 23499924 Common - hypothetical protein BRA0162 5 COG4893 COG4893, Uncharacterized protein conserved in bacteria Function unknown 23500143 Pathogen - hypothetical protein BRA0390 1 None None None 23499882 Common - transcriptional regulator, TetR family BRA0118 138 COG1309 AcrR, Transcriptional regulator Transcription 23500545 Common uxuA mannonate dehydratase BRA0814 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 23500647 Common lldD L-lactate dehydrogenase BRA0920 121 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 23500454 Common iolE iolE protein BRA0715 61 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 23499794 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA0027 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23499805 Pathogen - hypothetical protein BRA0038 1 None None None 23500218 Common - transporter, putative BRA0471 131 None None None 23499930 Common - citrate lyase, beta subunit, putative BRA0168 109 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 23499837 Common - transglycosylase, putative BRA0070 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 23500184 Common - epimerase/dehydratase family protein, putative BRA0435 187 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 23500566 Pathogen - hypothetical protein BRA0836 1 None None None 23499868 Common - hypothetical protein BRA0103 7 None None None 23500211 Common - transcriptional regulator, TetR family BRA0462 47 COG1309 AcrR, Transcriptional regulator Transcription 23500479 Common - hypothetical protein BRA0742 7 None None None 23500908 Common - branched-chain amino acid ABC transporter, ATP-binding protein BRA1196 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism