Bifidobacterium longum NCC2705, complete genome NC_004307 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 23465192 Nonpathogen - hypothetical protein BL0607 1 None None None 23464882 Common - hypothetical protein BL0281 13 COG0679 COG0679, Predicted permeases General function prediction only 23465197 Common - probable integral membrane transporter BL0613 96 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464711 Common - hypothetical protein BL0085 44 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 23465446 Common - possible ABC transporter component BL0872 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 23465791 Common - possible alpha beta hydrolase BL1223 101 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 23465507 Common - possible pyridoxine kinase BL0934 72 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 23464970 Nonpathogen - hypothetical protein BL0373 1 None None None 23464698 Common dnaQ possible exonuclease BL0071 172 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 23464972 Common - hypothetical protein with similarity to gp34 putative portal protein of bacteriophage Phi-C31 BL0375 59 COG4695 COG4695, Phage-related protein Function unknown 23466316 Common rbsK sugar kinase in PfkB family BL1772 176 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 23465481 Common - possible cyclomaltodextrinase or neopullalanase BL0907 151 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 23465276 Common - narrowly conserved protein with unknown function BL0695 12 None None None 23466229 Common hprT hypoxanthine-guanine phosphoribosyltransferase BL1681 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 23465454 Common - conserved hypothetical protein with duf175 BL0880 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 23465025 Common - hypothetical protein kinase in ABC1 family BL0427 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 23465946 Common xerC site-specific tyrosine recombinase XerC BL1384 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23464979 Nonpathogen - hypothetical protein BL0382 1 None None None 23466020 Nonpathogen - hypothetical protein BL1464 1 None None None 23465462 Common - hypothetical transmembrane protein with unknown function BL0888 8 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 23466178 Nonpathogen - hypothetical protein BL1629 1 None None None 23465053 Common - narrowly conserved hypothetical protein BL0457 55 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 23466040 Common - narrowly conserved hypothetical protein BL1484 7 None None None 23464941 Common - similar to ATP binding protein of ABC transporter BL0341 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 23465531 Common - possible Had-type hydrolase BL0958 119 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 23465860 Common hisH imidazole glycerol phosphate synthase subunit HisH BL1299 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 23465089 Common recR recombination protein RecR BL0499 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 23466056 Common - inositol-5-monophosphate dehydrogenase BL1500 230 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 23466087 Common - hypothetical integral membrane with weak similarity to proteins in BioY family BL1534 44 COG1268 BioY, Uncharacterized conserved protein General function prediction only 23465582 Nonpathogen - hypothetical protein BL1013 1 COG4640 COG4640, Predicted membrane protein Function unknown 23464718 Common - probable DNA helicase II BL0092 224 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 23465178 Common - putative septation inhibitor protein BL0593 14 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 23465748 Common ftsX FtsX-like protein involved in cell division BL1182 57 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 23466078 Nonpathogen - hypothetical protein BL1524 1 None None None 23465258 Common - sortase-like protein similar to fimbria-associated protein of Actinomyces naeslundii BL0676 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 23465427 Common rplY probable 50S ribosomal protein L25 BL0853 187 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 23465820 Common mutT1 probable MutT1 protein BL1258 22 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 23465171 Common rodA protein involved in cell wall formation and stabilization of the FtsZ ring during cell division BL0586 193 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 23465935 Common - narrowly conserved hypothetical protein possibly in the MutT/Nudix family BL1373 83 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 23466036 Nonpathogen - hypothetical protein BL1480 1 None None None 23466201 Common lysS lysyl-tRNA synthetase BL1654 245 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 23465850 Common nusG probable transcription antitermination protein BL1288 214 COG0250 NusG, Transcription antiterminator Transcription 23464690 Common - hypothetical transmembrane protein with unknown function BL0063 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 23465060 Nonpathogen - hypothetical protein BL0467 1 None None None 23464686 Common - narrowly conserved hypothetical protein BL0059 19 None None None 23465526 Common nadE glutamine-dependent NAD(+) synthetase BL0953 210 COG0171 NadE, NAD synthase Coenzyme metabolism 23465184 Nonpathogen - hypothetical protein BL0599 1 None None None 23465764 Common - probable serine/threonine-protein kinase BL1198 150 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 23466237 Nonpathogen - hypothetical protein BL1690 1 None None None 23466166 Common rbfA ribosome-binding factor A BL1617 137 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 23465283 Common uvrC excinuclease ABC subunit C BL0703 224 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 23466354 Common - hypothetical protein BL1810 23 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 23466043 Nonpathogen - hypothetical protein BL1486a 1 None None None 23465516 Common clpX ATP-dependent protease ATP-binding subunit BL0943 224 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 23465782 Common baiC probable NADH-dependent flavin oxidoreductase YqjM BL1214 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 23465981 Nonpathogen - hypothetical transmembrane protein with unknown function BL1423 1 None None None 23465956 Common ctpE probable cation-transporting ATPase BL1396 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 23465992 Common gyrA2 DNA topoisomerase IV subunit A BL1434 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 23465074 Common - thymidylate kinase BL0484 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 23466189 Common - hypothetical protein BL1641 4 None None None 23465827 Common - hypothetical protein with similarity to dihydroorotate dehydrogenase BL1265 67 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 23464663 Common - probable ABC transport system permease protein for sugars BL0035 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 23465773 Common - hypothetical protein BL1206 5 None None None 23466246 Common - hypothetical transmembrane protein possibly involved in efflux transport BL1699 78 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23465999 Nonpathogen - hypothetical protein BL1443 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 23465030 Common - hypothetical protein in upf0013 BL0432 175 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 23465331 Common rpe ribulose-phosphate 3-epimerase BL0753 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 23465039 Common - narrowly conserved hypothetical protein BL0441 21 COG3429 COG3429, Glucose-6-P dehydrogenase subunit Carbohydrate transport and metabolism 23465697 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit BL1129 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 23464861 Common - LacI-type transcriptional regulator BL0258 127 COG1609 PurR, Transcriptional regulators Transcription 23466315 Common dcuC C4-dicarboxylate transporter BL1771 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 23464868 Common fadD1 probable long-chain-fatty acid CoA ligase BL0266 218 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 23465298 Common dnaJ chaperone protein BL0719 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 23465846 Common obgE GTPase ObgE BL1284 249 COG0536 Obg, Predicted GTPase General function prediction only 23466070 Common - widely conserved hypothetical transmembrane protein with dub81 BL1515 29 COG0730 COG0730, Predicted permeases General function prediction only 23465896 Common - probable endo-beta-N-acetylglucosaminidase; di-N-acetylchitobiosyl beta-N-acetylglucosaminidase BL1335 20 COG4724 COG4724, Endo-beta-N-acetylglucosaminidase D Carbohydrate transport and metabolism 23465487 Common - hypothetical protein with possible helix turn helix motif BL0913 2 COG1476 COG1476, Predicted transcriptional regulators Transcription 23465612 Common - hypothetical protein possibly involved in monovalent cation transport BL1045 86 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 23465358 Common - narrowly conserved hypothetical protein BL0782 61 COG3943 COG3943, Virulence protein General function prediction only 23464720 Common - hypothetical protein BL0094 92 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 23465380 Common - hypothetical protein with similarity to gene 66 protein of mycobacteriophage D29 BL0805 9 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 23465105 Common - hypothetical transmembrane protein in xanthine/uracil permeases family BL0515 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 23465756 Common - hypothetical transmembrane protein with unknown function BL1190 42 COG0730 COG0730, Predicted permeases General function prediction only 23466232 Common folP dihydropteroate synthase 1 BL1684 215 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 23464728 Common - possible inosine-uridine preferring nucleoside hydrolase BL0102 78 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 23465658 Common - hypothetical protein BL1089 20 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23466335 Common priA primosome assembly protein PriA BL1791 100 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 23464764 Common - permease of ABC transporter possibly for oligosaccharides BL0144 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23466248 Nonpathogen - hypothetical protein BL1701 1 None None None 23465288 Common tpi triosephosphate isomerase BL0708 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 23465300 Common bacA possible undecaprenol kinase BL0721 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 23465015 Nonpathogen - hypothetical protein BL0417 1 None None None 23465903 Common - NagC/XylR-type transciptional regulator BL1342 168 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23466264 Common - probable sugar O-acetyltransferase (thiogalactoside acetyltransferase BL1719 84 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 23465836 Common thrA homoserine dehydrogenase BL1274 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 23464735 Nonpathogen - hypothetical protein BL0109 1 None None None 23465376 Common - hypothetical protein with similarity to PimT BL0800 63 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 23465396 Common bcp possible thioredoxin-dependent thiol peroxidase BL0821 217 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 23465969 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase BL1409 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 23464783 Nonpathogen - hypothetical protein BL0167 1 None None None 23465963 Common - atypical histidine kinase sensor of two-component system BL1403 14 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 23465682 Common - hypothetical protein in ImpB/MucB/SamB family of UV repair proteins BL1114 36 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 23465924 Common gap glyceraldehyde 3-phosphate dehydrogenase C BL1363 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 23464795 Common - probable permease protein of ABC transporter system BL0180 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 23465342 Common - hypothetical protein with acyl transferase domain BL0765 19 COG0456 RimI, Acetyltransferases General function prediction only 23465851 Nonpathogen - hypothetical protein BL1289 1 None None None 23464948 Common psp1 hypothetical 14.5 kDa translational inhibitor protein BL0348 165 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 23465125 Common - probable integrase/recombinase BL0539 47 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 23465122 Common - hypothetical transmembrane protein with unknown function BL0534 21 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 23464769 Common - probable TetR-like transcriptional regulator BL0153 22 COG1309 AcrR, Transcriptional regulator Transcription 23465361 Common - possible alpha beta hydrolase BL0785 50 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 23465092 Common - narrowly conserved hypothetical protein with possible diacylglycerol kinase domain BL0502 67 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 23466287 Common - widely conserved hypothetical protein BL1742 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 23464683 Common - sugar permease of ABC transporter system BL0055 169 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23464986 Common ppa inorganic pyrophosphatase BL0389 182 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 23464881 Common gpi glucose-6-phosphate isomerase BL0279 188 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 23466009 Common - possible prolidase (X-Pro dipeptidase) or chlorohydrolase BL1453 109 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 23465870 Common - probable cation efflux protein BL1309 151 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 23464807 Common - narrowly conserved hypothetical protein BL0192 101 COG3177 COG3177, Uncharacterized conserved protein Function unknown 23465139 Common - probable cation-transporting ATPase V BL0554 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 23464845 Common - probable integrase/recombinase BL0239 112 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23466188 Common - permease of ABC transporter for sugars BL1640 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23465432 Common fadD2 long-chain-fatty-acid-CoA ligase BL0858 218 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 23464843 Common cpsF possible rhamnosyltransferase BL0236 26 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 23465677 Common - possible carboxylesterase or lipase BL1109 115 COG0657 Aes, Esterase/lipase Lipid metabolism 23466199 Common - hypothetical protein with N-terminal similarity to TPR repeat proteins and kinesin light chain isoform 3 BL1651 17 None None None 23466169 Common radA DNA repair protein RadA BL1620 204 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 23464651 Common gluC permease protein of ABC transporter for glutamate BL0023 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 23465563 Common - possible solute binding protein of ABC transporter system BL0994 117 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 23465651 Common - conserved hypothetical transmembrane protein in upf0013 BL1082 153 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 23465299 Common - hypothetical protein BL0720 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 23465800 Common abiLI hypothetical protein with similarity to AbiLI: abortive phage resistance protein BL1234 26 COG1106 COG1106, Predicted ATPases General function prediction only 23465135 Common fba fructose-bisphosphate aldolase BL0550 175 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 23465811 Common hutH histidine ammonia-lyase BL1249 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 23465816 Common upp uracil phosphoribosyltransferase BL1254 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 23465118 Common ilvC1 ketol-acid reductoisomerase BL0530 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 23464813 Common - hypothetical membrane protein with unknown function BL0198 9 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 23464955 Common atpC ATP synthase epsilon chain BL0356 115 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 23465033 Common amtP possible ammonium ion transporter BL0435 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 23465231 Common parB probable chromosome partitioning protein BL0648 182 COG1475 Spo0J, Predicted transcriptional regulators Transcription 23465686 Common - probable amino-acid binding protein for ABC transporter system BL1118 86 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23465586 Common sdaA L-serine dehydratase BL1017 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 23465411 Common - hypothetical protein BL0836 23 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 23465794 Common - narrowly conserved hypothetical protein BL1227 31 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 23465840 Common - hypothetical protein with unknown or transport function BL1278 8 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 23464962 Common atpB F0F1 ATP synthase subunit A BL0363 146 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 23466140 Common rplN 50S ribosomal protein L14 BL1590 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 23466216 Common alzD branched-chain amino acid permease BL1668 21 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 23465418 Common - conserved hypothetical transmembrane protein with unknown function BL0844 89 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 23464643 Common - 5'-nucleotidase family protein BL0015 60 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 23465974 Common - possible DNA binding protein BL1414 17 COG1395 COG1395, Predicted transcriptional regulator Transcription 23465517 Common clpP ATP-dependent Clp protease proteolytic subunit BL0944 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 23465544 Nonpathogen - fragment of beta galactosidase BL0975 1 None None None 23465213 Common gdhA glutamate dehydrogenase BL0630 172 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 23466133 Common rplB 50S ribosomal protein L2 BL1581 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 23465142 Nonpathogen - hypothetical protein BL0557 1 None None None 23465492 Common - possible efflux transporter protein BL0919 119 None None None 23465730 Common - probable solute binding protein of ABC transporter system for sugars BL1164 89 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23465550 Common - hypothetical protein with helix turn helix motif BL0981 19 COG1396 HipB, Predicted transcriptional regulators Transcription 23466161 Common abfA3 alpha-L-arabinosidase BL1611 31 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 23466274 Common - hypothetical protein with similarity to Ssb BL1729 19 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 23465104 Common - possible acyl protein synthase/acyl-CoA reductase-like protein BL0514 18 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 23464707 Common - conserved hypothetical protein in upf0074 BL0081 45 COG1959 COG1959, Predicted transcriptional regulator Transcription 23464919 Common pfs probable MTA/SAH nucleosidase BL0318 71 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 23465883 Common fstW probable FtsW-like protein BL1322 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 23464756 Common - hypothetical protein with acyl transferase domain BL0130 10 COG0456 RimI, Acetyltransferases General function prediction only 23465499 Common - translation-associated GTPase BL0926 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 23466182 Common - transcription antiterminator similar to LicT BL1633 30 COG3711 BglG, Transcriptional antiterminator Transcription 23466156 Common rpoA DNA-directed RNA polymerase subunit alpha BL1606 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 23465737 Common - probable LacI-type transcriptional regulator BL1171 126 COG1609 PurR, Transcriptional regulators Transcription 23465181 Nonpathogen - hypothetical protein BL0596 1 None None None 23465229 Common gidB glucose-inhibited division protein B BL0646 197 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 23464636 Common - narrowly conserved hypothetical protein BL0008 18 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 23465242 Common - hypothetical protein BL0659 5 None None None 23465241 Common - narrowly conserved hypothetical protein BL0658 30 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 23466068 Nonpathogen - hypothetical protein BL1513 1 None None None 23465916 Nonpathogen - hypothetical protein with possible similarity to FemA involved in pentaglycine interpeptide bridge in peptidoglycan BL1355 2 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 23465148 Common - probable type II restriction enzyme similar to Sau3AI BL0563 10 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 23465539 Common pta phosphate acetyltransferase BL0968 163 COG0280 Pta, Phosphotransacetylase Energy production and conversion 23465570 Common - histidine kinase sensor of two-component system BL1001 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 23464659 Common - histidine kinase sensor of two-component system BL0031 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 23466075 Common msmE sugar binding protein of ABC transporter system BL1521 88 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23465097 Common - hypothetical protein BL0507 8 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 23465325 Common - narrowly conserved hypothetical protein BL0748 24 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 23464876 Common - probable sugar kinase BL0274 65 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 23466172 Common - ribose-5-phosphate isomerase A BL1623 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 23465604 Common pacL2 PacL2 BL1038 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 23465559 Common uvrB excinuclease ABC subunit B BL0990 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 23465455 Common - possible endonuclease BL0881 140 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 23465723 Common oppF probable ATP binding protein of ABC transporter for peptides BL1157 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 23466112 Common rpmG 50S ribosomal protein L33 BL1560 95 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 23465048 Common - possible permease protein of ABC transporter system BL0451 28 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 23465047 Common - ATP binding protein of ABC transporter BL0450 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23465543 Nonpathogen - hypothetical protein BL0974 3 None None None 23466080 Common tdcB catabolic threonine dehydratase BL1527 203 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 23466181 Common ptsG PtsG BL1632 59 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 23466304 Common - hypothetical protein possibly involved in exopolysaccharide production BL1760 27 None None None 23464924 Common pcp pyrrolidone-carboxylate peptidase BL0323 53 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 23465270 Common - ATP binding protein of ABC transporter BL0689 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 23465477 Common - response regulator of two-component system BL0903 202 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 23465807 Common gif probable UDP-galactopyranose mutase BL1245 54 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 23465251 Common nrdI ribonucleotide reductase stimulatory protein BL0669 36 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 23465219 Common - hypothetical protein similar to orf 192 of M. smegmatis BL0636 19 COG5512 COG5512, Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives General function prediction only 23465327 Common - narrowly conserved hypothetical protein BL0749 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 23466098 Common rpsO 30S ribosomal protein S15 BL1545a 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 23465573 Common - hypothetical protein with similarity to eukaryotic phosphomannomutase BL1004 6 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 23466149 Common rplO 50S ribosomal protein L15 BL1599 215 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 23465666 Common tuf elongation factor Tu BL1097 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 23464856 Common - hypothetical protein BL0253 18 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23464839 Common fabG probable 3-oxoacyl-[acyl-carrier protein] reductase BL0232 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23465917 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase BL1356 205 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 23465009 Common ptsI PtsI BL0411 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 23465426 Common ilvE branched-chain amino acid aminotransferase BL0852 196 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 23465155 Common - hypothetical protein BL0570 54 COG2898 COG2898, Uncharacterized conserved protein Function unknown 23465088 Common - possible sortase-like protein BL0498 18 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 23466011 Common - hypothetical protein BL1455 13 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 161485603 Common - hypothetical protein BL0575 34 COG2510 COG2510, Predicted membrane protein Function unknown 23465307 Common ruvB Holliday junction DNA helicase B BL0729 221 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 23465000 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B BL0402 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 161485600 Common - S-ribosylhomocysteinase BL1152 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 23465843 Common rne ribonuclease G BL1281 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 23466200 Common - AraJ-like protein probably involved in transport of arabinose polymers BL1652 134 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464991 Common - probable solute binding protein of ABC transporter system BL0394 167 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23465059 Nonpathogen - hypothetical protein BL0466 1 None None None 23465581 Common - histidine kinase-like protein BL1012 94 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 23464985 Common - possible glycanase or glycogenase with amylase domain BL0388 104 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 23465530 Common - hypothetical protein with similarity to proteins in NlpA family of lipoproteins BL0957 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 23466127 Common adh2 Adh2 BL1575 183 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 23465936 Common nadA quinolinate synthetase BL1374 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 23464935 Common ogt methylated-DNA--protein-cysteine methyltransferase BL0335 205 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 23465837 Common thrB possible homoserine kinase BL1275 87 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 23465941 Common - widely conserved protein similar to those annotated as GTP-binding elongation factor TypA/BipA BL1379 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 23466028 Common - type II restriction enzyme very similar to EcoRII; endonuclease BL1472 13 None None None 23465183 Common - narrowly conserved hypothetical protein BL0598 18 None None None 23464662 Common - ATP binding protein of ABC transporter BL0034 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23464738 Common - conserved hypothetical protein with Duf77 BL0112 21 COG0011 COG0011, Uncharacterized conserved protein Function unknown 23465282 Common uvrA excinuclease ABC subunit A BL0702 235 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 23465991 Common - hypothetical protein with response regulator receiver domain BL1433 12 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23464691 Common - ATP binding protein of ABC transporter BL0064 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 23465753 Common mrsA probable phosphoglucomutase or phosphomannomutase BL1187 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 23464949 Common - narrowly conserved hypothetical protein BL0349 38 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 23464719 Common - narrowly conserved hypothetical protein BL0093 19 COG5282 COG5282, Uncharacterized conserved protein Function unknown 23466209 Common - hypothetical protein BL1662 4 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 23465357 Common - hypothetical protein BL0781 12 None None None 23465198 Common - thioredoxin reductase-like protein BL0614 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 23466055 Common icd1 isocitrate dehydrogenase BL1499 61 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 23465740 Common - possible ribosomal pseudouridine synthase BL1174 148 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 23465189 Common ppc phosphoenolpyruvate carboxylase BL0604 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 23464699 Common - hypothetical protein BL0072 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 23466267 Common guaB inosine-5'-monophosphate dehydrogenase BL1722 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 23464971 Common - hypothetical protein with similarity to putative terminase gp4 of mycobacteriophage TM4 BL0374 3 None None None 23465191 Nonpathogen - hypothetical protein BL0606 1 None None None 23465628 Common argR arginine repressor-like protein BL1059 78 COG1438 ArgR, Arginine repressor Transcription 23465275 Common - possible ABC transporter permease for cobalt BL0694 14 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 23465482 Common - possible TetR-type transcriptional regulator BL0908 46 COG1309 AcrR, Transcriptional regulator Transcription 23466297 Common nrdG anaerobic ribonucleoside-triphosphate reductase activating protein BL1753 62 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 23465461 Common - ATP binding protein of ABC transporter BL0887 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23465038 Common zwf2 glucose-6-phosphate 1-dehydrogenase BL0440 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 23466355 Common - widely conserved MoxR-like protein in magnesium chelatase family BL1811 171 COG0714 COG0714, MoxR-like ATPases General function prediction only 23466115 Common fdxC ferredoxin BL1563 144 COG1146 COG1146, Ferredoxin Energy production and conversion 23465789 Common gcvH glycine cleavage system H protein BL1221 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 23466179 Common pgm phosphoglucomutase BL1630 213 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 23465431 Common pntA NAD(P) transhydrogenase subunit alpha part 1 BL0857 164 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 23464678 Nonpathogen - hypothetical protein BL0050 1 None None None 23465179 Common - conserved membrane protein in rhomboid family BL0594 155 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 23465164 Nonpathogen - hypothetical protein BL0579 1 None None None 23464804 Common - sugar permease of ABC transporter system BL0189 155 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23465216 Common - hypothetical protein BL0633 16 None None None 23466030 Common - narrowly conserved hypothetical protein BL1474 12 COG3177 COG3177, Uncharacterized conserved protein Function unknown 23466108 Common - possible acetytransferase BL1556 90 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 23466307 Common bglB possible beta-glucosidase B BL1763 76 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 23465542 Common - hypothetical protein BL0971 5 None None None 23465724 Common oppD probable ATP-binding protein of ABC transporter system for peptides BL1158 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 23464749 Common - widely conserved hypothetical protein in the Rlu family of pseudouridine synthase BL0123 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 23465052 Common - widely conserved hypothetical membrane protein BL0455 51 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 23466088 Common jadJ JadJ BL1535 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 23465356 Nonpathogen - hypothetical protein BL0780 1 None None None 23466081 Common - Sir2-type regulatory protein BL1528 146 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 23466233 Common sulD SulD BL1685 200 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 23466249 Common - hypothetical membrane protein possibly involved in transport BL1702 6 None None None 23465747 Common - hypothetical protein with weak C-terminal similarity to TraG BL1181 10 COG3942 COG3942, Surface antigen General function prediction only 23466247 Common fms peptide deformylase BL1700 174 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 23465341 Common - narrowly conserved hypothetical protein BL0764 35 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 23464709 Common - hypothetical protein BL0083 11 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 23465859 Common hisB imidazoleglycerol-phosphate dehydratase BL1297 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 23464778 Common - probable permease protein of ABC transporter system BL0162 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 23464904 Common ffh signal recognition particle protein BL0303 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 23465375 Common - narrowly conserved hypothetical protein BL0799 57 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 23465017 Common - hypothetical protein in upf0001 BL0419 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 23465061 Common gltX glutamyl-tRNA synthetase BL0469 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 23466092 Common - hypothetical protein with gram positive cell wall anchoring domain BL1539 21 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 23465672 Common - possible low specificity-threonine aldolase BL1103 68 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 23465195 Common - LacI-type transcriptional regulator BL0610 122 COG1609 PurR, Transcriptional regulators Transcription 23465964 Common - hypothetical protein BL1404 2 None None None 23465961 Nonpathogen - hypothetical protein in acetyl transferase family BL1401 2 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 23464784 Nonpathogen - hypothetical protein BL0168 1 None None None 23466100 Common - widely conserved hypothetical protein with xanthine/uracil permease signature BL1547 135 COG2252 COG2252, Permeases General function prediction only 23465717 Common - hypothetical protein BL1151 13 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 23464710 Common - narrowly conserved hypothetical protein BL0084 202 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 23465975 Common recA recombinase A BL1415 242 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 23466167 Common truB tRNA pseudouridine synthase B BL1618 242 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 23465923 Common - conserved hypothetical protein very similar to YbaK of E. coli BL1362 104 COG2606 EbsC, Uncharacterized conserved protein Function unknown 23465826 Common - hypothetical protein BL1264 20 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 23466228 Common - narrowly conserved hypothetical protein similar to MesJ BL1680 202 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 23466317 Nonpathogen - hypothetical protein BL1773 1 None None None 23466130 Common rplC 50S ribosomal protein L3 BL1578 216 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 23465653 Common - hypothetical protein BL1084 8 None None None 23465729 Common - probable solute binding protein of ABC transporter system for sugars BL1163 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23465854 Common morA morphine 6-dehydrogenase BL1292 176 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 23466240 Common - probable repressor protein in (NagC/XylR) family BL1693 173 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23465928 Common rpmI 50S ribosomal protein L35 BL1366a 57 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 23465781 Common - dihydroorotate dehydrogenase 2 BL1213 200 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 23465024 Common - LacI-type transcriptional regulator BL0426 128 COG1609 PurR, Transcriptional regulators Transcription 23465508 Common - hypothetical protein in upf0102 BL0935 128 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 23465808 Nonpathogen - hypothetical membrane protein with unknown function BL1246 1 COG5373 COG5373, Predicted membrane protein Function unknown 23466312 Common - probable LacI-type transcriptional regulator BL1768 127 COG1609 PurR, Transcriptional regulators Transcription 23465774 Common mutY probable A/G-specific adenine glycosylase BL1207 222 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 23465955 Nonpathogen - hypothetical protein BL1395 1 None None None 23465297 Common hrcA heat-inducible transcription repressor BL0718 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 23466276 Common - hypothetical protein BL1731 10 COG3247 HdeD, Uncharacterized conserved protein Function unknown 23465106 Common - probable MerR-type-transcriptional regulator BL0516 64 COG0789 SoxR, Predicted transcriptional regulators Transcription 23465332 Common lgt prolipoprotein diacylglyceryl transferase BL0754 200 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 23465407 Nonpathogen - hypothetical protein BL0832 1 None None None 23464821 Common rgpDc protein possibly involved in ATP-driven polysaccharide export BL0207 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 23465915 Common smc chromosome partitioning protein Smc BL1354 182 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 23465032 Common glnB nitrogen regulatory protein N-II BL0434 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 23464890 Common - MerR-type transcriptional regulator BL0289 88 COG0789 SoxR, Predicted transcriptional regulators Transcription 23465230 Common parA chromosome partitioning protein ParA BL0647 221 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 23465576 Common - narrowly conserved hypothetical protein BL1007 10 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 23465817 Nonpathogen - hypothetical protein BL1255 1 None None None 23465012 Common rpsR 30S ribosomal protein S18-2 BL0414 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 23465830 Common - probable aminotransferase BL1268 215 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 23464644 Common - narrowly conserved hypothetical protein BL0016 24 COG5373 COG5373, Predicted membrane protein Function unknown 23465687 Common - probable permease protein for ABC transporter system for amino-acids BL1119 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 23465387 Nonpathogen - hypothetical protein BL0812 3 None None None 23465369 Common pyrI aspartate carbamoyltransferase regulatory subunit BL0793 62 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 23465895 Common - probable pentosidase or hexosidase BL1334 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 23466134 Common rpsS 30S ribosomal protein S19 BL1582 239 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 23464725 Common - hypothetical protein with possible acylase domain BL0099 2 COG0657 Aes, Esterase/lipase Lipid metabolism 23465044 Common - hypothetical membrane protein with similarity to phage infection protein BL0447 36 COG1511 COG1511, Predicted membrane protein Function unknown 23466277 Common map methionine aminopeptidase BL1732 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 23464963 Nonpathogen - hypothetical protein BL0364 1 None None None 23465209 Nonpathogen - hypothetical protein BL0626 1 None None None 23465136 Common htpX possible protease HtpX BL0551 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 23465810 Common - IclR-type transcriptional regulator BL1248 116 COG1414 IclR, Transcriptional regulator Transcription 23466286 Common - probable aspartate aminotransferase BL1741 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 23465204 Common gntK probable gluconokinase BL0620 79 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 23465943 Common pheA probable chorismate mutase (CM); prephenate dehydratase BL1381 173 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 23466191 Common galT2 galactose-1-phosphate uridylyltransferase BL1643 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 23464836 Common rmlB1 dTDP-glucose 4,6-dehydratase enzyme involved in rhamnose biosynthesis BL0229 229 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 23465738 Common - hypothetical protein with similarity to HipA BL1172 33 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 23465049 Common - possible permease protein of ABC transporter system BL0452 42 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 23465379 Common - probable transcriptional activator similar to TenA BL0804 77 COG0819 TenA, Putative transcription activator Transcription 23464637 Common - hypothetical protein BL0009 27 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 23465082 Common asd aspartate-semialdehyde dehydrogenase BL0492 188 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 161485602 Common - bifunctional cytidylate kinase/GTP-binding protein BL0738 229 COG1160 COG1160, Predicted GTPases General function prediction only 23465121 Common scrR LacI-type transcriptional regulator BL0533 124 COG1609 PurR, Transcriptional regulators Transcription 23465093 Common - hypothetical protein BL0503 5 None None None 23465683 Common ahcY S-adenosyl-L-homocysteine hydrolase BL1115 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 23465156 Common - narrowly conserved hypothetical protein BL0571 11 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 23465584 Common greA transcription elongation factor GreA BL1015 204 COG0782 GreA, Transcription elongation factor Transcription 23465360 Common - hypothetical protein BL0784 127 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 23465661 Common - protein with similarity to CrcB BL1092 50 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 23466060 Common tsf elongation factor Ts BL1504 215 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 23464857 Common - narrowly conserved hypothetical protein BL0254 24 None None None 23465257 Common - possible cell surface protein similar to FimA fimbrial subunit of Actinomyces naeslundii BL0675 14 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 23464706 Common - hypothetical protein with homology to glutaredoxin-like protein BL0079 17 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 23466198 Common - hypothetical protein BL1650 7 None None None 23465525 Common - hypothetical protein BL0952 4 None None None 23465650 Common - possible endonuclease III BL1081 69 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 23465933 Common - narrowly conserved hypothetical protein BL1371 119 COG1354 COG1354, Uncharacterized conserved protein Function unknown 23465676 Common purL PurL BL1108 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 23465926 Common - hypothetical protein with low similarity to spermidine synthase BL1365 47 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 23465165 Common - hypothetical protein BL0580 16 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 23465308 Nonpathogen - hypothetical protein with duf129 BL0730 3 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 23465075 Common topA DNA topoisomerase I BL0485 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 23465631 Common argB acetylglutamate kinase BL1062 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 23465884 Common murG N-acetylglucosaminyl transferase BL1323 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 23466022 Nonpathogen - hypothetical protein BL1466 1 None None None 23464992 Common valS valyl-tRNA synthetase BL0395 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23466173 Common rnh ribonuclease H BL1624 147 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 23465397 Nonpathogen - hypothetical protein BL0822 1 None None None 23465476 Common - histidine kinase sensor of two-component system BL0902 57 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 23464812 Common - possible ATP binding protein of ABC transporter BL0197 232 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23465989 Common - probable ribokinase BL1431 206 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 23465667 Common fusA elongation factor G BL1098 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 23464927 Common - possible protease or peptidase BL0326 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 23466019 Nonpathogen - hypothetical protein BL1463 1 None None None 23465328 Common pgsA possible CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase BL0750 180 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 23465250 Common nrdH glutaredoxin-like protein NrdH BL0668 37 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 23465629 Common argF ornithine carbamoyltransferase BL1060 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 23466111 Common - possible cystathionine gamma lyase BL1559 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 23465228 Common jag narrowly conserved hypothetical protein with possible ssDNA binding domain BL0645 71 COG1847 Jag, Predicted RNA-binding protein General function prediction only 23464916 Common pstS phosphate-binding transport protein of ABC transporter system BL0315 118 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 23466217 Common - narrowly conserved hypothetical protein BL1669 97 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 23465008 Common glpF glycerol uptake facilitator-like protein in Mip family BL0410 117 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 23466012 Common rimI probable ribosomal-protein-alanine N-acetyltransferase BL1456 179 COG0456 RimI, Acetyltransferases General function prediction only 23466148 Common rpmD 50S ribosomal protein L30 BL1598 122 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 23464741 Common thiM hydroxyethylthiazole kinase BL0115 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 23466097 Nonpathogen - hypothetical protein BL1545 1 None None None 23464889 Common - hypothetical transmembrane protein with unknown function BL0288 6 None None None 23466076 Common msmF sugar permease of ABC transporter system BL1522 179 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23465491 Common - hypothetical protein with probable serine/threonine-protein kinase domain BL0918 151 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 23465801 Common - hypothetical protein BL1235 4 None None None 23465701 Common - protein with weak similarity to components of ABC transporter BL1133 165 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 23466255 Common - possible XylR-type repressor BL1710 142 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23464826 Common - narrowly conserved hypothetical protein with possible glycosyltransferase domain BL0213 15 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 23465172 Common pbpA probable penicillin binding protein transpeptidase BL0587 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 23464753 Common dnaE DNA polymerase III subunit alpha BL0127 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 23465532 Common - putative phosphoketolase BL0959 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 23465243 Common - widely conserved protein with eukaryotic protein kinase domain BL0660 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 23466107 Common - hypothetical protein in the 5-formyltetrahydrofolate cyclo-ligase family BL1555 146 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 23465558 Common - widely conserved hypothetical protein with similarity to tellurium resistance protein BL0989 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 23465143 Nonpathogen - hypothetical protein BL0558 1 None None None 23464768 Common aroP aromatic amino acid transport protein AroP BL0152 147 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 23465096 Common - hypothetical membrane protein with unknown function BL0506 13 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 23464954 Common - hypothetical protein BL0355 37 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 23465117 Common aglA probable alpha-1,4-glucosidase; maltase-like enzyme BL0529 164 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 23465147 Common - hypothetical protein BL0562 102 COG0393 COG0393, Uncharacterized conserved protein Function unknown 23465381 Common - hypothetical protein BL0806 114 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 23465447 Common - hypothetical protein BL0873 9 None None None 23465239 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Cmk; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase BL0656 117 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 23466151 Common adk adenylate kinase BL1601 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 23465003 Common - narrowly conserved hypothetical protein with possible methylase domain BL0405 15 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 23466325 Common mrr mrr restriction endonuclease BL1781 52 COG1715 Mrr, Restriction endonuclease Defense mechanisms 23465326 Common - hypothetical membrane protein with unknown function BL0748a 22 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 23464682 Common - hypothetical protein BL0054 5 None None None 23465603 Nonpathogen - hypothetical protein BL1037 1 None None None 23466309 Common - possible MarR-type transcriptional regulator BL1765 26 COG1846 MarR, Transcriptional regulators Transcription 23464877 Common - LacI-type transcriptional regulator BL0275 126 COG1609 PurR, Transcriptional regulators Transcription 23465595 Common - possible N-acetyl transferase BL1028 114 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 23466344 Common purB adenylosuccinate lyase BL1800 231 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 23465456 Common alaS alanyl-tRNA synthetase BL0882 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23465922 Common ispH IspH protein involved in conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into IPP and DMAPP BL1361 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 23465002 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C BL0404 116 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 23466224 Common - narrowly conserved hypothetical transmembrane protein BL1676 104 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23465302 Common thrS threonyl-tRNA synthetase BL0724 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23464946 Common - glycerol-3-phosphate dehydrogenase BL0346 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 23466208 Common - hypothetical protein with C-terminal homology to TrsG of S. aureus conjugation system BL1661 8 COG3942 COG3942, Surface antigen General function prediction only 23466187 Common - permease of ABC transporter for sugars BL1639 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23465962 Common - response regulator of two-component system BL1402 219 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 23466241 Common - probable sugar binding protein of ABC transporter for pentoses BL1694 72 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 23466058 Common def polypeptide deformylase BL1502 208 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 23464814 Common - hypothetical protein BL0199 8 None None None 23466250 Common - hypothetical membrane protein in major facilitator transporter family BL1703 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464673 Common - probable glycosyltransferase BL0045 35 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 23466333 Common fmt methionyl-tRNA formyltransferase BL1789 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 23466207 Common serC phosphoserine aminotransferase BL1660 127 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 23465994 Common - hypothetical protein BL1436 17 None None None 23464770 Common - ATP binding protein of ABC transporter BL0154 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23465784 Common - probable transcriptional regulator with cyclic nucleotide-binding domain BL1216 161 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 23464913 Common pstB probable ATP-binding protein of ABC transporter system for phosphate BL0312 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 23465754 Nonpathogen - hypothetical protein BL1188 1 None None None 23465954 Common - conserved hypothetical protein with duf90 BL1394 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 23465614 Common - hypothetical protein BL1047 2 None None None 23465834 Common argS arginyl-tRNA synthetase BL1272 246 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23464758 Common - hypothetical protein with similarity to pip phage infection protein of L. lactis BL0138 37 COG1511 COG1511, Predicted membrane protein Function unknown 23464661 Common - probable solute binding protein of ABC transporter system possibly for sugars BL0033 91 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23466180 Common glcP D-Glucose-proton symporter BL1631 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464729 Common - possible solute binding protein of ABC transporter BL0103 77 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 23465857 Common hisD histidinol dehydrogenase BL1295 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 23466082 Common - possible IclR-type transcriptional regulator BL1529 74 COG1414 IclR, Transcriptional regulator Transcription 23466261 Common - permease of ABC transporter for branched-chain amino acids BL1716 150 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 23466230 Common ftsH ATP-dependent zinc metallopeptidase involved in cell division BL1682 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 23465076 Nonpathogen - possible pre-pilin peptidase BL0486 2 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 23465951 Common - possible exodeoxyribonuclease BL1391 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 23465518 Common clp1 ATP-dependent Clp protease proteolytic subunit 1 BL0945 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 23464794 Common - probable permease protein of ABC transporter system BL0179 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 23464910 Common - possible oxidoreductase of the aldo/keto reductase family BL0309 177 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 23465133 Common - probable voltage gated channel protein BL0548 159 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 23465169 Common - hypothetical protein with FHA domain BL0584 41 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 23465967 Common - narrowly conserved hypothetical protein BL1407 103 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 23465694 Common - probable solute binding protein of ABC transporter system BL1126 112 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 23464762 Common - LacI-type transcriptional regulator BL0142 126 COG1609 PurR, Transcriptional regulators Transcription 23465254 Common - probable glycosyltransferase BL0672 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23466259 Common - solute binding protein of ABC transporter for branched-chain amino acids BL1714 150 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 23465119 Common ilvC2 ketol-acid reductoisomerase BL0531 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 23465340 Common - narrowly conserved hypothetical protein BL0762 5 None None None 23465770 Nonpathogen - hypothetical protein BL1203 1 None None None 23465378 Nonpathogen - hypothetical protein BL0803 1 None None None 23464905 Common - hypothetical protein BL0304 9 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 23466257 Common prfA peptide chain release factor 1 BL1712 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 23465374 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase BL0798 133 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 23464665 Common - probable efflux-type transporter BL0037 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464781 Common - possible symporter BL0165 62 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 23465398 Nonpathogen - hypothetical protein BL0823 1 None None None 23464713 Common dapF diaminopimelate epimerase BL0087 200 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 23466045 Common - hypothetical protein BL1488 12 None None None 23465266 Common hisF HisF cyclase BL0685 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 23466013 Common gcp metalloendopeptidase Gcp BL1457 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 23464880 Nonpathogen - hypothetical protein BL0278 1 None None None 23466279 Common - widely conserved hypothetical protein BL1734 35 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 23464653 Common - hypothetical secreted protein with probable acid phosphatase domain BL0025 39 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 23465442 Common - hypothetical protein with NifU-like domain BL0868 76 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 23466266 Common rfe possible undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase BL1721 197 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 23465766 Common moxR methanol dehydrogenase regulatory protein homolog BL1199a 177 COG0714 COG0714, MoxR-like ATPases General function prediction only 23465051 Common - narrowly conserved hypothetical protein BL0454 24 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 23465057 Nonpathogen - hypothetical protein BL0463 1 None None None 23464875 Common araD L-ribulose-5-phosphate 4-epimerase BL0273 150 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 23466089 Common pccB propionyl-CoA carboxylase beta chain BL1536 217 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 23465640 Common - narrowly conserved hypothetical protein BL1071 19 COG4721 COG4721, Predicted membrane protein Function unknown 23464696 Common - similar to orotidine 5'-phosphate decarboxylase BL0069 57 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 23465023 Common - solute binding protein of ABC transporter system BL0425 92 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23466114 Common - possible cationic amino acid transporter BL1562 184 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 23466296 Common nrdD anaerobic ribonucleoside triphosphate reductase BL1752 94 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 23465337 Common - hypothetical membrane protein with unknown function BL0759 5 None None None 23464899 Common stbB plasmid stability protein StbB BL0298 49 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 23465281 Common - hypothetical protein BL0701 4 None None None 23464809 Common kup2 kup system potassium uptake protein BL0194 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 23464734 Common - hypothetical protein with similarity to serine protease inhibitors BL0108 30 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 23464934 Common - hypothetical protein with helix turn helix motif BL0333 13 COG1476 COG1476, Predicted transcriptional regulators Transcription 23465475 Common - probable ATP binding protein of ABC transporter BL0901 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 23466031 Nonpathogen - hypothetical protein BL1475 1 None None None 23465670 Nonpathogen - hypothetical protein BL1101 1 None None None 23466177 Common - narrowly conserved hypothetical protein BL1628 5 None None None 23465404 Common dppA1 probable oligopeptide binding protein of ABC transporter BL0829 190 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 23465464 Common pcrA ATP-dependent DNA helicase PcrA BL0890 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 23466025 Common topB DNA topoisomerase III BL1469 246 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 23465509 Common - conserved hypothetical protein in chelatase subunits D/I family BL0936 195 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 23465510 Common - hypothetical protein with partial similarity to smf DNA processing protein BL0937 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 23466105 Common - large hypothetical protein BL1552 41 None None None 23465623 Common thiG thiazole synthase BL1055 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 23465162 Common - TelA-like protein associated with cryptic tellurite resistance BL0577 28 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 23465875 Common - narrowly conserved hypothetical protein with helicase motifs BL1314 31 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 23465062 Nonpathogen - hypothetical protein BL0470 1 None None None 23465058 Common - narrowly conserved hypothetical protein BL0464 12 None None None 23465419 Common glxK glycerate kinase BL0845 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 23466163 Nonpathogen - hypothetical protein BL1614 1 None None None 23465186 Common - widely conserved hypothetical protein BL0601 107 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 23465225 Common rnpA ribonuclease P protein component BL0642a 28 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 23464841 Nonpathogen - hypothetical protein BL0234 1 None None None 23465575 Common - hypothetical protein BL1006 11 None None None 23465154 Nonpathogen - hypothetical protein BL0569 1 None None None 23464855 Common mntH H(+)-stimulated manganese uptake system protein BL0252 106 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 23464779 Common - probable permease protein of ABC transporter system BL0163 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 23464695 Common carB CarB BL0068 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 23465541 Common - 3-phosphoshikimate 1-carboxyvinyltransferase BL0970 222 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 23466126 Common - probable repressor in the Rok (NagC/XylR) family BL1574 113 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23465647 Common - possible integral membrane permease protein BL1078 51 COG0679 COG0679, Predicted permeases General function prediction only 23464708 Nonpathogen - hypothetical protein BL0082 1 None None None 23465196 Nonpathogen - hypothetical protein BL0611 1 None None None 23465529 Common - ATP binding protein of ABC transporter BL0956 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 23465520 Common tig trigger factor BL0947 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 23465500 Common proC pyrroline-5-carboxylate reductase BL0927 211 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 23465140 Common degP possible DO serine protease BL0555 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 23466042 Nonpathogen - hypothetical protein BL1486 1 None None None 23465590 Common eno enolase BL1022 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 23465797 Common - hypothetical protein BL1230 2 None None None 23465886 Common - narrowly conserved hypothetical protein with possible DNA interaction motif BL1325 40 COG3636 COG3636, Predicted transcriptional regulator Transcription 23465866 Common hrpA ATP-dependent helicase BL1305 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 23466352 Common - hypothetical protein BL1808 3 None None None 23465716 Common yfnA probable amino acid transporter BL1150 193 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 23466168 Common ribF protein RibF [includes: riboflavin kinase (flavokinase); Fmn adenylyltransferase BL1619 203 COG0196 RibF, FAD synthase Coenzyme metabolism 23465580 Common wblE WhiB-type transcription regulator BL1011 19 None None None 23465775 Common yibK probable RNA methyltransferase BL1208 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 23464854 Common - widely conserved hypothetical transport protein BL0251 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23465320 Common - narrowly conserved hypothetical protein BL0743 18 None None None 23465063 Common - narrowly conserved hypothetical protein BL0471 54 COG3152 COG3152, Predicted membrane protein Function unknown 23466032 Common - hypothetical protein BL1476 62 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 161485605 Common lacY galactoside permease BL0106 40 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 23465613 Common - hypothetical protein possibly involved in monovalent cation transport BL1046 93 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 23464629 Common cspA cold shock protein BL0001 171 COG1278 CspC, Cold shock proteins Transcription 23465005 Common - conserved hypothetical protein with Duf195 BL0407 140 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 23465095 Common - hypothetical protein BL0505 7 None None None 23465382 Common - hypothetical protein with similarity to lipase and esterase BL0807 77 COG0657 Aes, Esterase/lipase Lipid metabolism 23465244 Nonpathogen - hypothetical protein BL0661 1 None None None 23465498 Nonpathogen - hypothetical protein BL0925 1 None None None 23465557 Common pyk pyruvate kinase BL0988 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 23465309 Common apt adenine phosphoribosyltransferase BL0731 168 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 23466091 Common - protein with similarity to holo-[acyl-carrier protein] synthase BL1538 5 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 23465489 Nonpathogen - hypothetical protein BL0916 1 COG2898 COG2898, Uncharacterized conserved protein Function unknown 23466150 Common secY preprotein translocase subunit SecY BL1600 220 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 23464869 Common - ATP binding protein of ABC transporter similar to Vex2 (VexP2) of S. pneumoniae BL0267 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23466159 Common - narrowly conserved hypothetical protein BL1609 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 23466322 Common - truncated type I restriction system specificity protein BL1778 10 None None None 23465885 Common murC UDP-N-acetylmuramate--alanine ligase BL1324 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 23465646 Nonpathogen - fragment of beta-glucuronidase BL1077 1 None None None 23464652 Common gluD permease protein of ABC transporter for glutamate BL0024 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 23465388 Common - hypothetical protein BL0813 3 None None None 23465227 Common - conserved hypothetical transmembrane protein in the 60 kDa inner membrane protein family BL0644 209 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 23464808 Common - widely conserved hypothetical protein BL0193 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 23465203 Common - hypothetical protein BL0619 28 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23465593 Common pth peptidyl-tRNA hydrolase BL1026 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 23466110 Common groES co-chaperonin GroES BL1558 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 23465280 Common - hypothetical protein BL0700 16 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 23464893 Common - hypothetical protein BL0292 19 COG5373 COG5373, Predicted membrane protein Function unknown 23464801 Common - possible esterase BL0186 48 COG0657 Aes, Esterase/lipase Lipid metabolism 23465664 Common - possible atypical LysR-type transcriptional regulator BL1095 112 COG0583 LysR, Transcriptional regulator Transcription 23466302 Nonpathogen - hypothetical protein BL1758 1 None None None 23464953 Common fkbP1 possible secreted peptidyl-prolyl cis-trans isomerase protein BL0354 130 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 23465022 Common - sugar permease of ABC transporter system BL0424 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23465596 Common - narrowly conserved hypothetical protein BL1029 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 23465656 Common - possible MarR-type transcriptional regulator BL1087 27 COG1846 MarR, Transcriptional regulators Transcription 23464926 Common - hypothetical protein BL0325 178 COG1496 COG1496, Uncharacterized conserved protein Function unknown 23465949 Common dppC probable permease protein of ABC-transporter for peptides BL1389 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23465232 Common trxB thioredoxin reductase BL0649 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 23464733 Common - probable LacI-type transcriptional regulator BL0107 126 COG1609 PurR, Transcriptional regulators Transcription 23465630 Common argD acetylornithine aminotransferase BL1061 236 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 23465210 Nonpathogen - hypothetical protein BL0627 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 23465607 Common - ATP binding protein of ABC transporter BL1041 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 23465253 Common nrdF ribonucleotide-diphosphate reductase subunit beta BL0671 147 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 23465934 Common - hypothetical protein BL1372 153 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 23464995 Common rho transcription termination factor Rho BL0398 210 COG1158 Rho, Transcription termination factor Transcription 23465444 Common - probable ATP binding protein of ABC transporter BL0870 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 23465278 Nonpathogen - hypothetical protein BL0698 1 None None None 23465208 Nonpathogen - hypothetical protein with possible TetR regulatory domain BL0625 1 None None None 23466162 Common - LacI-type transcriptional regulator BL1613 126 COG1609 PurR, Transcriptional regulators Transcription 23465329 Common hisG ATP phosphoribosyltransferase BL0751 213 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 23465153 Common msrA bifunctional methionine sulfoxide reductase A/B protein BL0568 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 23466190 Common - putative desulfatase possibly for mucin BL1642 19 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 23464744 Common ftsZ cell division protein FtsZ BL0118 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 23465872 Common - hypothetical protein with LysM domain of membrane-bound lytic murein transglycosylase BL1311 5 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 23465424 Common - conserved hypothetical transmembrane protein with unknown function BL0850 132 COG2860 COG2860, Predicted membrane protein Function unknown 23466065 Common - hypothetical protein in the ThiJ/PfpI family BL1509 147 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 23464981 Nonpathogen - hypothetical protein with N-acetylmuramoyl-L-alanine amidase domain BL0384 7 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 23464767 Common - narrowly conserved hypothetical protein BL0151 34 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 23465944 Common tyrA probable prephenate dehydrogenase BL1382 149 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 23465660 Common - protein with similarity to CrcB BL1091 55 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 23464988 Nonpathogen - hypothetical protein BL0391 1 None None None 23465533 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein BL0960 241 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 23465813 Common gltX2 probable glutamyl-tRNA synthetase BL1251 213 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 23464977 Common - hypothetical protein with low similarity to gp 40 protein of bacteriophage Phi-C31 BL0380 2 None None None 23465684 Common - possible chlorohydrolase-like protein BL1116 122 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 23465746 Common smpB SsrA-binding protein BL1180 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 23465743 Common - permease protein of ABC transporter system BL1177 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 23465639 Common - ATP binding protein of ABC transporter BL1070 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 23464638 Common clpC protease BL0010 219 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 23465127 Common - truncated alpha-glucosidase BL0542 73 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 23465217 Common gyrA1 DNA gyrase subunit A BL0634 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 23464830 Common - narrowly conserved hypothetical protein BL0217 20 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 23465561 Common rpsA 30S ribosomal protein S1 BL0992 230 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 23466003 Common - possible phosphoglycerate mutase BL1447 89 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 23466289 Nonpathogen - hypothetical protein BL1745 1 None None None 23464688 Common - possible TetR-type transcriptional regulator BL0061 5 COG1309 AcrR, Transcriptional regulator Transcription 23465137 Common fprA probable ferredoxin/ferredoxin-NADP reductase BL0552 189 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 23464646 Common aspS aspartyl-tRNA synthetase BL0018 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23465041 Common gnt 6-phosphogluconate dehydrogenase BL0444 181 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 23465083 Common askB aspartokinase BL0493 182 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 23464829 Common - narrowly conserved hypothetical protein BL0216 31 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 23466135 Common rplV 50S ribosomal protein L22 BL1583 212 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 23466186 Common - solute binding protein of ABC transporter for sugars BL1638 71 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23464645 Common hisS histidyl-tRNA synthetase BL0017 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23464631 Common - hypothetical protein BL0003 5 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 23465988 Common - hypothetical protein BL1430 24 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 23465688 Common - probable ATP binding protein of ABC transporter for amino-acids BL1120 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 23466235 Common tesB acyl-CoA thioesterase II BL1687 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 23465814 Common - possible phosphodiesterase BL1252 35 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 23465090 Common dnaX DNA polymerase III subunits gamma and tau BL0500 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 23464947 Common - narrowly conserved hypothetical protein with acyl transferase domain BL0347 61 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 23464815 Nonpathogen - hypothetical protein BL0200 2 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 23464788 Common - hypothetical protein with similarity to family of proteins in M. tuberculosis BL0172 5 None None None 23465202 Common - hypothetical protein in DPS family BL0618 114 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 23465732 Common abfA2 alpha-L-arabinofuranosidase BL1166 32 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 23465942 Nonpathogen - hypothetical protein BL1380 1 None None None 23466285 Common - probable oxidoreductase BL1740 170 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 23465792 Common - narrowly conserved hypothetical protein BL1224 6 None None None 23466197 Common - hypothetical membrane protein possibly involved in transport BL1649 9 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 23465835 Common lysA probable diaminopimelate decarboxylase BL1273 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 23465702 Nonpathogen - hypothetical protein BL1134 11 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 23464820 Nonpathogen - hypothetical membrane protein with unknown function BL0206 1 None None None 23465848 Common aspC aspartate aminotransferase BL1286 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 23466119 Common - narrowly conserved hypothetical protein BL1567 53 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 23466131 Common rplD 50S ribosomal protein L4 BL1579 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 23464763 Common - permease of ABC transporter possibly for oligosaccharides BL0143 138 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23465259 Nonpathogen - hypothetical protein BL0677 1 None None None 23465289 Nonpathogen secG preprotein translocase subunit SecG BL0709 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 23465077 Common - probable penicillin-binding protein BL0487 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 23464918 Common - histidine kinase sensor of two-component system BL0317 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 23466258 Common - possible methylase protein BL1713 212 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 23466314 Common - ribonucleoside hydrolase RihC BL1770 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 23466256 Common rpmE 50S ribosomal protein L31 BL1711 205 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 23466063 Common cdsA probable phosphatidate cytidylyltransferase BL1507 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 23464727 Common uppS undecaprenyl pyrophosphate synthetase BL0101 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 23465519 Common - hypothetical protein BL0946 68 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 23466231 Common folE GTP cyclohydrolase I BL1683 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 23465405 Nonpathogen - hypothetical protein BL0830 1 None None None 23465725 Common - probable ABC transporter permease protein for peptides BL1159 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23464766 Common - possible arabinosidase BL0146 7 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 23464780 Common - hypothetical protein related to thiamine biosynthesis lipoprotein ApbE BL0164 8 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 23465377 Common - hypothetical protein with carboxyesterase/lipase domain BL0801 24 COG0400 COG0400, Predicted esterase General function prediction only 23465865 Common - hypothetical protein BL1304 4 None None None 23464793 Common - possible alpha-galactosidase BL0177 14 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 23465695 Common - hypothetical protein BL1127 3 None None None 23466120 Common - possible 2-hydroxyacid dehydrogenase BL1568 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 23465301 Common - narrowly conserved hypothetical protein BL0722 22 None None None 23465715 Common alr alanine racemase BL1149 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 23465703 Common - ATP binding protein of ABC transporter BL1135 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23464838 Common - possible decarboxylase with tpp domain+d236 BL0231 98 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 23465527 Common - widely conserved hypothetical protein BL0954 174 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 23465373 Common metF 5,10-methylenetetrahydrofolate reductase BL0797 149 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 23464782 Common - conserved hypothetical protein with tetrapyrole methylase domain BL0166 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 23466170 Nonpathogen - hypothetical protein BL1621 1 None None None 23465821 Common ppk polyphosphate kinase BL1259 162 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 23466132 Common rplW 50S ribosomal protein L23 BL1580 215 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 23465765 Common - large protein with C-terminal fibronectin type III domain BL1199 115 None None None 23465267 Common hisI phosphoribosyl-AMP cyclohydrolase BL0686 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 23465553 Common - conserved hypothetical protein with duf34 BL0984 110 COG0327 COG0327, Uncharacterized conserved protein Function unknown 23466278 Common gltA2 citrate synthase 1 BL1733 194 COG0372 GltA, Citrate synthase Energy production and conversion 23465921 Common - hypothetical protein in aldose epimerase family BL1360 45 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 23465641 Common - hypothetical protein BL1072 142 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 23465982 Common - widely conserved hypothetical protein with acyl transferase domain BL1424 106 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 23466242 Common - ATP binding protein of ABC transporter for pentoses BL1695 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23465107 Common - chaperone protein similar to DnaJ BL0517 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 23465383 Nonpathogen - hypothetical protein BL0808 1 None None None 23466345 Common - hypothetical membrane protein with unknown function BL1801 24 COG4721 COG4721, Predicted membrane protein Function unknown 23464755 Common - narrowly conserved hypothetical protein BL0129 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 23464701 Common - permease protein of ABC transporter system BL0074 183 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 23464866 Common - ATP binding protein of ABC transporter BL0264 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 23464888 Common - nicotinate phosphoribosyltransferase BL0287 103 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 23465828 Common nox NADH oxidase BL1266 233 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 23465333 Common trpA tryptophan synthase subunit alpha BL0755 219 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 23465705 Common - protein similar to hex regulon repressor BL1137 98 COG1737 RpiR, Transcriptional regulators Transcription 23465894 Common - narrowly conserved hypothetical protein BL1333 8 None None None 23465993 Common - narrowly conserved hypothetical protein BL1435 31 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 23465295 Common tal transaldolase BL0715 139 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 23465100 Common dedA DedA integral membrane protein BL0510 154 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 23465783 Common - possible penicillin-binding protein BL1215 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 23466332 Common ilvD dihydroxy-acid dehydratase BL1788 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 23465315 Common rluB ribosomal large subunit pseudouridine synthase B BL0737 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 23464936 Common - hypothetical protein BL0336 5 None None None 23464817 Common - hypothetical protein involved in polysaccharide biosynthesis BL0203 24 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 23465959 Nonpathogen - hypothetical protein BL1399 1 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 23464660 Common - hypothetical protein BL0032 16 None None None 23465953 Common - narrowly conserved hypothetical transmembrane protein BL1393 17 None None None 23465549 Common - hypothetical protein BL0980 23 COG4832 COG4832, Uncharacterized conserved protein Function unknown 23465745 Common - probable solute binding protein of ABC transporter system BL1179 161 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23464771 Common - large transmembrane protein possibly involved in transport BL0155 37 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 23465615 Common - hemolysin-like protein with S4 domain found in bacteria and plants BL1048 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 23466143 Common rpsN 30S ribosomal protein S14 BL1593 212 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 23464937 Common - hypothetical protein possibly in TetR transcriptional regulator family BL0337 8 COG1309 AcrR, Transcriptional regulator Transcription 23465185 Common trpS tryptophanyl-tRNA synthetase BL0600 245 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23464672 Common - narrowly conserved hypothetical protein BL0044 5 COG3601 COG3601, Predicted membrane protein Function unknown 23465904 Common nagB glucosamine-6-phosphate deaminase BL1343 88 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 23465350 Common - MutT-like protein BL0774 51 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 23464993 Nonpathogen - hypothetical protein BL0396 1 None None None 23466125 Common - probable glycogen operon protein GlgX BL1573 139 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 23466353 Nonpathogen - hypothetical protein BL1809 1 None None None 23465501 Common pap proline iminopeptidase BL0928 17 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 23465463 Nonpathogen - hypothetical protein BL0889 3 None None None 23466236 Common - putative ABC transporter ATP-binding protein BL1688 234 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 23465277 Common - hypothetical protein BL0697 10 None None None 23465648 Common - fragment of LacA BL1079 138 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 23464685 Common - possible butyryl-CoA dehydrogenase BL0058 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 23464823 Common - hypothetical protein with similarity to LicD required for phosphorylcholine incorporation in teichoic and lipoteichoic acids BL0209 17 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 23465422 Common lepA GTP-binding protein LepA BL0848 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 23465714 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein BL1148 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 23465540 Common ackA acetate kinase BL0969 161 COG0282 ackA, Acetate kinase Energy production and conversion 23465480 Common cstA carbon starvation protein A BL0906 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 23465528 Common - permease protein of ABC transporter system BL0955 93 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 23465578 Common - hypothetical protein with similarity to putative transcriptional regulator of streptomyces BL1009 63 COG1316 LytR, Transcriptional regulator Transcription 161485604 Common leuA 2-isopropylmalate synthase BL0488 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 23466046 Common - hypothetical protein with limited similarity to PrgB aggregation substance BL1489 5 None None None 23466052 Nonpathogen - hypothetical protein BL1495 1 None None None 23466094 Nonpathogen - hypothetical protein BL1541 1 None None None 23466113 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase BL1561 114 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 23465141 Common tgt queuine tRNA-ribosyltransferase BL0556 228 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 23465443 Common - NifS-like aminotranferase BL0869 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 23464929 Common - hypothetical protein with possible methylase domain BL0328 210 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 23464736 Nonpathogen - hypothetical protein BL0110 1 None None None 23464874 Common araA L-arabinose isomerase BL0272 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 23464654 Common - hypothetical protein BL0026 2 None None None 23465338 Common - hypothetical membrane protein with unknown function BL0760 7 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 23466057 Common fadD3 possible long-chain-fatty acid CoA ligase BL1501 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 23464987 Common - integral membrane protein in the upf0059 BL0390 64 COG1971 COG1971, Predicted membrane protein Function unknown 23465050 Common - narrowly conserved hypothetical membrane protein BL0453 17 COG4393 COG4393, Predicted membrane protein Function unknown 23464697 Common - guanylate kinase BL0070 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 23465433 Common era GTP-binding protein Era BL0859 223 COG1159 Era, GTPase General function prediction only 23464891 Common - possible reductase BL0290 195 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 23466214 Common dfrA dihydrofolate reductase BL1666 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 23464898 Common ilvH acetolactate synthase 3 regulatory subunit BL0297 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 23465362 Common cpsY LysR-type transcriptional regulator BL0786 179 COG0583 LysR, Transcriptional regulator Transcription 23466106 Nonpathogen - hypothetical protein BL1553 1 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 23466319 Common - fragment of beta galactosidase BL1775 46 None None None 23466206 Nonpathogen - hypothetical protein BL1659 1 None None None 23464872 Nonpathogen - hypothetical protein BL0270 1 None None None 23466291 Common - large-conductance mechanosensitive channel BL1747 139 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 23465798 Nonpathogen - hypothetical protein BL1231 1 None None None 23465622 Common thiF thiamine biosynthesis protein BL1054 224 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 23465874 Common serA D-3-phosphoglycerate dehydrogenase BL1313 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 23466035 Common - narrowly conserved hypothetical protein similar to TrsK BL1479 9 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 23465588 Common - hypothetical protein BL1020 26 COG1507 COG1507, Uncharacterized conserved protein Function unknown 23465193 Nonpathogen - hypothetical protein BL0608 1 None None None 23465511 Common sdhA succinate dehydrogenase flavoprotein subunit BL0938 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 23465583 Common - hypothetical protein BL1014 115 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 23466215 Common ptpA low molecular weight protein-tyrosine-phosphatase BL1667 120 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 23465399 Common - conserved hypothetical protein with duf3 BL0824 111 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 23464828 Common - possible glycosyltransferase BL0215 144 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23466004 Common corA possible magnesium and cobalt transport protein BL1448 35 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 23464902 Common cysS cysteinyl-tRNA synthetase BL0301 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23465372 Common - choloylglycine hydrolase BL0796 38 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 23465406 Nonpathogen - hypothetical protein BL0831 1 None None None 23465665 Common - hypothetical protein BL1096 4 None None None 23465594 Common - possible formate transporter BL1027 85 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 23464684 Common - possible beta-hexosaminidase A BL0056 47 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 23465987 Common gyrB2 DNA gyrase subunit B BL1429 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 23465260 Nonpathogen - hypothetical protein BL0678 1 None None None 23465211 Common - similar to aspartate aminotransferase BL0628 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 23465252 Common nrdE ribonucleotide-diphosphate reductase subunit alpha BL0670 219 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 23465014 Common rpsF 30S ribosomal protein S6 BL0416 191 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 23464952 Common - hypothetical protein BL0353 2 None None None 23465871 Common lexA LexA repressor BL1310 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 23465606 Nonpathogen - hypothetical protein BL1040 1 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 23465587 Common - possible exopolyphosphatase-like protein BL1019 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 23465445 Common - possible ABC transporter component BL0871 172 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 23465490 Common - hypothetical protein with possible helix turn helix motif BL0917 3 None None None 23465425 Common - conserved hypothetical protein similar to MazG BL0851 152 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 23465004 Common - hypothetical protein with similarity to Streptomyces orf annotated as putative uridine 5'-monophosphate synthase BL0406 11 None None None 23465084 Common askA aspartokinase BL0494 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 23464746 Common - narrowly conserved hypothetical protein BL0120 17 None None None 23464743 Common - possible NifR3-like protein BL0117 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 23465173 Common pknA probable serine-threonine protein kinase BL0588 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 23465973 Common - CinA-like protein BL1413 152 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 23465056 Common - probable LysR-type transcriptional regulator BL0460 179 COG0583 LysR, Transcriptional regulator Transcription 23465852 Common rplK 50S ribosomal protein L11 BL1290 237 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 23465094 Nonpathogen - hypothetical protein BL0504 1 None None None 23465776 Common - hypothetical protein BL1209 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 23465497 Common - hypothetical protein BL0924 5 COG5324 COG5324, Uncharacterized conserved protein Function unknown 23465224 Common rpmH 50S ribosomal protein L34 BL0642 188 None None None 23465359 Common - aspartate aminotransferase BL0783 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 23465845 Common rpmA 50S ribosomal protein L27 BL1283 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 23466350 Nonpathogen - hypothetical protein BL1806 1 None None None 23465812 Common clpB protease of ClpA/ClpB type BL1250 225 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 23465126 Common - probable integrase/recombinase BL0540 112 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23465534 Common - hypothetical membrane protein with possible acetylase function BL0962 94 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 23466153 Common rpmJ 50S ribosomal protein L36 BL1603 134 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 23465562 Common folD bifunctional methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase BL0993 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 23465226 Common - widely conserved hypothetical protein with duf37 BL0643 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 23465605 Nonpathogen - hypothetical protein BL1039 1 None None None 23465659 Common - possible alcohol dehydrogenase BL1090 202 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 23465138 Common - hypothetical protein BL0553 48 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23465554 Common polA DNA polymerase I BL0985 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 58036265 Common rpsK 30S ribosomal protein S11 BL1604.1 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 23465245 Common - hypothetical protein BL0662 18 None None None 23464647 Common - narrowly conserved hypothetical protein BL0019 6 None None None 23465474 Common - hypothetical protein BL0900 3 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 23465556 Common - possible NTP pyrophosphatase in MutT family BL0987 138 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 23466342 Common hup DNA-binding protein Hu BL1798 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 23466305 Common - probable beta-1,3-exoglucanase BL1761 9 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 23466288 Common - hypothetical transmembrane protein with unknown function BL1743 20 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 23465314 Common - probable membrane channel protein BL0736 57 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 23465134 Common purA adenylosuccinate synthetase BL0549 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 23465815 Common - hypothetical protein with duf163 BL1253 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 23464892 Common coaD phosphopantetheine adenylyltransferase BL0291 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 23465806 Common rmlB2 dTDP-glucose 4,6-dehydratase BL1244 227 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 23465046 Common - hypothetical protein BL0449 3 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 23466136 Common rpsC 30S ribosomal protein S3 BL1584 244 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 23465207 Nonpathogen - hypothetical protein BL0624 1 None None None 23465091 Common - possible TetR-type transcriptional regulator BL0501 56 COG1309 AcrR, Transcriptional regulator Transcription 23465689 Common purF amidophosphoribosyltransferase precursor BL1121 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 23465346 Nonpathogen - hypothetical protein BL0770 1 None None None 23465918 Common sigH RNA polymerase sigma factor RpoE BL1357 164 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 23465201 Common - widely conserved hypothetical protein with duf21 and CBS domains BL0617 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 23464664 Common - probable ABC transporter permease protein for sugars BL0036 108 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 23466118 Common - conserved hypothetical transmembrane protein with duf6 BL1566 56 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 23465390 Nonpathogen - hypothetical protein BL0815 1 None None None 23466196 Nonpathogen - hypothetical protein BL1648 1 None None None 23466160 Common - narrowly conserved hypothetical protein in transglutaminase family BL1610 94 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 23464687 Common - hypothetical protein with limited similarity to C-terminal part of trans-aconitate methyltransferase BL0060 34 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 23466066 Common - hypothetical protein BL1511 7 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 23465384 Nonpathogen - hypothetical protein BL0809 1 None None None 23464978 Common - phage related protein: putative minor tail protein BL0381 8 COG5412 COG5412, Phage-related protein Function unknown 23465163 Nonpathogen - hypothetical protein BL0578 2 None None None 23464844 Common - galactosyl transferase CpsD BL0237 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 23464980 Nonpathogen - hypothetical protein BL0383 1 None None None 23464639 Common codA cytosine deaminase BL0011 73 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 23465673 Common - possible glycosyltransferase BL1104 98 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 23465751 Nonpathogen - hypothetical protein BL1185 2 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 23466014 Common - probable integrase/recombinse BL1458 140 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23465685 Common - narrowly conserved hypothetical protein BL1117 56 COG3542 COG3542, Uncharacterized conserved protein Function unknown 23464969 Nonpathogen - hypothetical protein with low similarity to L. caseii bacteriophage terminase small subunit gp3 BL0372 1 None None None 161485597 Common vsr possible XorII very-short-patch-repair endonuclease BL1739 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 23466271 Common - possible pyruvate formate-lyase activating enzyme BL1726 98 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 23464911 Nonpathogen - hypothetical protein BL0310 5 COG4907 COG4907, Predicted membrane protein Function unknown 23465296 Common tkt transketolase BL0716 219 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 23464842 Common cps2F probable glycosyltransferase BL0235 115 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23465416 Nonpathogen - hypothetical protein BL0841 1 None None None 23465913 Nonpathogen - hypothetical protein BL1352 1 None None None 23465638 Common - possible permease protein of ABC transporter for cobalt BL1069 21 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 23464806 Nonpathogen - hypothetical protein BL0191 1 None None None 23465339 Nonpathogen - hypothetical protein BL0761 1 None None None 23464831 Common - fragment of S. mutans orf7 BL0218 12 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 23466171 Nonpathogen - hypothetical protein BL1622 1 None None None 23464994 Common - chorismate mutase BL0397 36 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 23466158 Common truA tRNA pseudouridine synthase A BL1608 232 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 23465566 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase BL0997 154 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 23466195 Common - hypothetical protein BL1647 8 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 23465040 Common - probable 6-phosphogluconolactonase BL0443 90 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 23465635 Common pheT phenylalanyl-tRNA synthetase beta chain BL1066 229 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 23465452 Common aroC chorismate synthase BL0878 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 23466015 Nonpathogen - hypothetical protein BL1459 1 None None None 23464655 Common - narrowly conserved hypothetical protein BL0027 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 23465473 Common - hypothetical protein BL0899 6 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 23465804 Nonpathogen - hypothetical protein BL1242 2 None None None 23465790 Common - hypothetical protein with N-terminal similarity to NADH pyrophosphatase BL1222 102 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 23466356 Common ung uracil-DNA glycosylase BL1812 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 23465752 Common def peptide deformylase BL1186 203 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 23466339 Common - hypothetical proteasome-associated protein BL1795 15 None None None 23465436 Common - PhoH-like protein BL0862 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 23466005 Common - solute binding protein of ABC transporter system BL1449 121 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23465642 Common - hypothetical protein BL1073 17 None None None 23465129 Common abfA1 alpha-L-arabinosidase BL0544 31 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 23465637 Common - possible rRNA methylase BL1068 178 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 23464832 Nonpathogen - hypothetical protein BL0225 1 None None None 23466270 Common - widely conserved hypothetical protein with duf51 BL1725 75 COG1355 COG1355, Predicted dioxygenase General function prediction only 23465849 Common secE preprotein translocase subunit SecE BL1287 17 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 23466073 Common aga alpha-galactosidase BL1518 46 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 23466283 Common - hypothetical protein with probable acetyltransferase domain BL1738 9 COG0456 RimI, Acetyltransferases General function prediction only 23465234 Common - conserved hypothetical membrane protein in MviN family BL0651 114 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 23465731 Common - probable solute binding protein of ABC transporter system for sugars BL1165 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23465206 Common - hypothetical protein BL0622 40 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23465345 Nonpathogen - hypothetical protein BL0769 1 None None None 23465912 Common - hypothetical protein BL1351 5 None None None 23466064 Common - widely conserved hypothetical protein BL1508 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 23466165 Common infB translation initiation factor IF-2 BL1616 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 161485598 Common rpsB 30S ribosomal protein S2 BL1503 218 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 23465880 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase BL1319 206 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 23464967 Nonpathogen - hypothetical protein BL0369 1 None None None 23465819 Nonpathogen - hypothetical protein BL1257 1 None None None 23465704 Common - hypothetical protein BL1136 60 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 23466321 Common ileS isoleucyl-tRNA synthetase BL1777 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23466212 Common - hypothetical protein BL1664a 7 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 23465152 Common - hypothetical protein BL0567 16 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 23465649 Common lacA galactoside O-acetyltransferase BL1080 193 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 23465864 Common - hypothetical transmembrane protein possibly involved in transport BL1303 47 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23465940 Common - probable sugar transporter BL1378 148 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 23465568 Common glgB glycogen branching enzyme BL0999 152 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 23466029 Common - modification methylase very similar to EcoRII (cytosine-specificmethyltransferase BL1473 125 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 23465577 Common whiB2 WhiB-type transcription regulator BL1008 19 None None None 23465114 Common - probable LacI-type transcriptional regulator BL0525 126 COG1609 PurR, Transcriptional regulators Transcription 23464921 Common aroG2 phospho-2-dehydro-3-deoxyheptonate aldolase BL0320 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 23464974 Nonpathogen - hypothetical protein BL0377 1 None None None 23464632 Common - hypothetical protein BL0004 2 None None None 23465261 Common - narrowly conserved hypothetical protein BL0679 14 None None None 23464923 Common - hypothetical protein BL0322 130 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 23465742 Common - ATP binding protein of ABC transporter BL1176 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 23465334 Common trpBC tryptophan synthase subunit beta BL0756 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 23465293 Nonpathogen - hypothetical protein BL0713 1 None None None 23466301 Common bglX BglX BL1757 129 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 23464700 Common - possible phospholipase/carboxylesterase BL0073 36 COG0400 COG0400, Predicted esterase General function prediction only 23465274 Common - ATP binding protein of ABC transporter BL0693 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 23464959 Common atpH ATP synthase delta chain BL0360 52 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 23465960 Common - hypothetical protein with similarity to z5950 product of Escherichia coli O157:H7 BL1400 73 COG1479 COG1479, Uncharacterized conserved protein Function unknown 23465609 Common - possible hydrolyase with Pf00702 domain BL1042 157 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 23466205 Common - histidine kinase sensor of two component system BL1658 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 23465223 Common dnaA chromosomal replication initiator protein DnaA BL0640 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 23466290 Nonpathogen - hypothetical protein BL1746 1 None None None 23464675 Common ppgK similar to Mycobacterium tuberculosis polyphosphate glucokinase (polyphosphate-glucose phosphotransferase) also similar to members of ROK family of transcriptional regulators BL0047 53 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23465706 Common - similar to alpha-L-arabinofuranosidase A BL1138 14 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 23466326 Common hsdM HsdM BL1782 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 23464816 Nonpathogen - hypothetical protein BL0202 1 None None None 23464800 Common - LacI-type transcriptional regulator BL0185 129 COG1609 PurR, Transcriptional regulators Transcription 23466142 Common rplE 50S ribosomal protein L5 BL1592 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 23465131 Common - LacI-type transcriptional regulator BL0546 122 COG1609 PurR, Transcriptional regulators Transcription 23465893 Common - probable sugar permease of ABC transporter system BL1332 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23466079 Common agl oligo-1,6-glucosidase BL1526 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 23465321 Common - probable hydrolase or phosphatase BL0744 109 COG0546 Gph, Predicted phosphatases General function prediction only 23466152 Common infA translation initiation factor If-1 BL1602 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 23465548 Common tag DNA-3-methyladenine glycosylase I BL0979 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 23465364 Common pyrE orotate phosphoribosyltransferase BL0788 138 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 23465108 Common grpE GrpE protein BL0519 173 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 23464867 Common - fragment of arabinose permease BL0265 7 None None None 23464721 Common - narrowly conserved hypothetical protein BL0095 16 None None None 23465175 Common pabA para-aminobenzoate synthase glutamine amidotransferase component II BL0590 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 23466226 Common - hypothetical transmembrane protein with unknown function BL1678 8 None None None 23464790 Common - narrowly conserved hypothetical protein BL0174 30 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 23464903 Common - hypothetical protein BL0302 20 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 23465600 Common proA gamma-glutamyl phosphate reductase BL1034 195 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 23466116 Common - N-succinyldiaminopimelate aminotransferase BL1564 182 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 23465678 Nonpathogen - hypothetical protein BL1110 4 None None None 23466084 Common - narrowly conserved hypothetical protein BL1531 19 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 23465726 Common - similar to ABC transporter permease protein for peptides BL1160 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23465159 Nonpathogen - hypothetical protein BL0574 1 None None None 23465887 Common - D-tyrosyl-tRNA deacylase BL1326 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 23464848 Common - probable integrase/recombinase BL0244 205 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23465389 Common - hypothetical protein BL0814 5 None None None 23465591 Common - possible oxidoreductase in aldo-keto reductase family BL1023 179 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 23465536 Common glmU UDP-N-acetylglucosamine pyrophosphorylase BL0964 234 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 23464765 Common - hypothetical protein BL0145 5 None None None 23464852 Common rfbP undecaprenyl-phosphate sugar phosphotransferase BL0249 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 23465535 Common prsA2 ribose-phosphate pyrophosphokinase BL0963 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 23465977 Nonpathogen - hypothetical protein BL1417 1 None None None 23466117 Common - DNA-damage-inducible protein P BL1565 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 23465750 Common prfB peptide chain release factor 2 BL1184 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 23465777 Common - hypothetical protein BL1209a 38 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 23465971 Common ftsK cell division protein FtsK BL1411 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 23464928 Common trmD tRNA (guanine-N1)-methyltransferase BL0327 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 23464670 Common - narrowly conserved hypothetical protein in upf 0044 BL0042 44 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 23465690 Common purM phosphoribosylaminoimidazole synthetase BL1122 233 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 23465861 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase BL1300 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 23465459 Common - hypothetical protein BL0885 85 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 23465465 Common xpt xanthine phosphoribosyltransferase BL0891 43 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 23465523 Common pflA pyruvate formate-lyase 1 activating enzyme BL0950 123 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 23465268 Common trpE anthranilate synthase component I BL0687 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 23466331 Common rpoZ DNA-directed RNA polymerase subunit omega BL1787 19 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 23466047 Nonpathogen - hypothetical protein BL1490 1 None None None 23465417 Common - widely conserved hypothetical transmembrane protein with duf013 BL0842 116 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 23465761 Common - possible transport protein BL1195 31 None None None 23465625 Nonpathogen - hypothetical protein BL1056 1 None None None 23465070 Common fhs formate--tetrahydrofolate ligase BL0478 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 23465907 Common - probable permease of ABC transporter for peptides BL1346 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23464835 Common - possible fused dTDP-4-keto-L-rhamnose reductase and dTDP-4-keto-6-deoxyglucose-3,5-epimerase enzyme involved in rhamnose biosynthesis BL0228 173 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 23464792 Common - probable LacI-type transcriptional regulator BL0176 125 COG1609 PurR, Transcriptional regulators Transcription 23466121 Common - conserved hypothetical protein in upf 0029 BL1569 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 23466351 Common - hypothetical protein BL1807 19 None None None 23466083 Common - probable IclR-type transcriptional regulator BL1530 114 COG1414 IclR, Transcriptional regulator Transcription 23465435 Common - hypothetical protein BL0861 39 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 23464760 Common - hypothetical protein in PgaM phosphoglycerate mutase family BL0140 157 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 23465512 Common - probable iron sulfur protein associated with succinate dehydrogenase/fumarate reductase BL0939 189 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 23464873 Common - possible amidotransferase subunit BL0271 117 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 23465011 Common rplI 50S ribosomal protein L9 BL0413 212 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 23465167 Common - probable dipeptidyl peptidase IV BL0582 44 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 23464703 Common gltL ATP binding protein of ABC transporter for glutamate/aspartate BL0076 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 23464786 Common metG methionyl-tRNA synthetase BL0170 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23466300 Common - possible TetR-type transcriptional regulator BL1756 86 COG1309 AcrR, Transcriptional regulator Transcription 23466175 Common - possible class I pyridine nucleotide-disulfideoxidoreductase BL1626 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 23464715 Common - conserved hypothetical protein with phosphoesterase domain BL0089 124 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 23465313 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase BL0735 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 23465906 Common - probable solute-binding protein of ABC transporter for peptides BL1345 188 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23465741 Common glmS D-fructose-6-phosphate amidotransferase BL1175 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 23465786 Common leuB 3-isopropylmalate dehydrogenase BL1218 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 23465294 Common - branched-chain amino acid transport system carrier protein BL0714 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 23465900 Common - protein in PfkB family of sugar kinase BL1339 118 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 23465035 Common - probable TetR-type transcriptional regulator BL0437 71 COG1309 AcrR, Transcriptional regulator Transcription 23465438 Common - conserved hypothetical protein with similarity to SdrD of S. coelicolor BL0864 157 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 23465727 Common - solute binding protein of ABC transporter systemy for peptides BL1161 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 23465352 Common - truncated stage III sporulation protein J (SpoIIIJ) homolog BL0776 94 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 23465085 Common - narrowly conserved hypothetical protein BL0495 37 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23464908 Common - possible Rim-like protein involved in efficient processing of 16S rRNA BL0307 107 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 23464712 Common murI glutamate racemase BL0086 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 23466124 Common rpsI 30S ribosomal protein S9 BL1572 240 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 23465980 Common trpD anthranilate phosphoribosyltransferase 1 BL1422 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 23465833 Common - possible TetR-type transcriptional regulator BL1271 77 COG1309 AcrR, Transcriptional regulator Transcription 23464748 Common lspA possible lipoprotein signal peptidase BL0122 69 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 23466023 Common - possible TraG-related protein BL1467 21 COG3942 COG3942, Surface antigen General function prediction only 23465484 Common pyrP probable purine or uracil permease BL0910 121 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 23465772 Common rpoB DNA-directed RNA polymerase subunit beta BL1205 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 23465930 Common - probable integrase/recombinase BL1368 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23465986 Common hrdB RNA polymerase sigma factor RpoD BL1428 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 23464822 Common - possible permease protein of ABC transporter system for export of polysaccharide BL0208 116 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 23465055 Common - hypothetical protein BL0459 28 COG0716 FldA, Flavodoxins Energy production and conversion 23466252 Common - possible sugar permease BL1706 73 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 23465423 Common rpsT 30S ribosomal protein S20 BL0849 30 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 23464633 Common - response regulator of two-component system BL0005 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23465795 Nonpathogen - hypothetical protein BL1228 1 None None None 23466103 Common rplL 50S ribosomal protein L7/L12 BL1550 201 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 23465585 Common fkbP Fk506-binding protein BL1016 129 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 23464694 Common carA carbamoyl phosphate synthase small subunit BL0067 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 23465939 Common - possible pyridoxal-phosphate-dependent aminotransferase BL1377 234 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 23464759 Common - possible NADPH-flavin oxidoreductase; flavin reductase P; NADPH-Fmn oxidoreductase BL0139 72 COG0778 NfnB, Nitroreductase Energy production and conversion 23465353 Common - hypothetical membrane protein with possible transport function BL0777 24 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23465200 Common icfA probable carbonic anhydrase BL0616 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 23465174 Common pknB probable serine/threonine-protein kinase PknB BL0589 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 23465194 Common - hypothetical protein possibly related to helicases BL0609 63 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 23465262 Common - possible tRNA/rRNA methyltransferase BL0680 200 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 23465064 Common - widely conserved hypothetical protein BL0472 53 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 23464914 Common pstA probable phosphate binding-protein of ABC transporter system BL0313 231 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 23464939 Common - hypothetical protein in upf0003 BL0339 215 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 23465246 Common - possible voltage-gated potassium channel protein BL0664 105 None None None 23465768 Common - hypothetical protein with transglutaminase domain BL1201 24 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 23465391 Common - hypothetical protein BL0816 5 COG3013 COG3013, Uncharacterized conserved protein Function unknown 23466034 Nonpathogen - hypothetical protein BL1478 1 None None None 23464656 Common - probable DEAD box-like helicase BL0028 140 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 23465626 Common argH argininosuccinate lyase BL1057 225 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 23466037 Nonpathogen - hypothetical protein BL1481 1 None None None 23465858 Common hisC histidinol-phosphate aminotransferase BL1296 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 23465958 Nonpathogen - hypothetical protein with possible helix turn helix motif BL1398 1 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 23466243 Common - probable ABC transport system permease protein for sugars BL1696 108 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 23465020 Common - narrowly conserved hypothetical protein BL0422 28 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 23466093 Common - possible cell surface protein BL1540 4 None None None 23465441 Common - conserved hypothetical protein with duf59 BL0867 146 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 23465335 Common - probable endonuclease IV BL0757 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 23465719 Common recQ ATP-dependent DNA helicase RecQ BL1153 233 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 23465555 Common - conserved hypothetical protein with a response regulator receiver domain BL0986 220 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 23465616 Common - conserved hypothetical protein with possible phosphatase function BL1049 105 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 23464772 Common aapA amino acid permease BL0156 117 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 23466343 Common - narrowly conserved hypothetical membrane protein BL1799 16 COG0392 COG0392, Predicted integral membrane protein Function unknown 23464944 Common - possible solute binding protein of ABC transporter system BL0344 37 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 23465101 Common - hypothetical protein in haloacid dehalogenase-like hydrolase family BL0511 100 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 23465996 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase BL1438 177 COG0756 Dut, dUTPase Nucleotide transport and metabolism 23466320 Common - probable aminotransferase BL1776 204 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 23465920 Common - hypothetical protein with possible aldose-1-epimerase domain BL1359 65 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 23465692 Common aldH fatty aldehyde dehydrogenase BL1124 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 23466221 Common fucO L-1,2-propanediol oxidoreductase BL1673 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 23466269 Common - possible helicase BL1724 54 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 23465403 Common - hypothetical protein BL0828 4 None None None 23465892 Common - probable sugar permease of ABC transporter system BL1331 154 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23466260 Common - permease of ABC transporter for branched-chain amino acids BL1715 161 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 23464997 Common - hypothetical protein BL0400 7 None None None 23465739 Common - hypothetical protein with similarity to HipA BL1173 45 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 23465304 Common - hypothetical protein BL0726 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 23464895 Common rpmF 50S ribosomal protein L32 BL0294 67 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 23464731 Common cscA beta-fructofuranosidase (sucrase/invertase); possible inulinase BL0105 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 23464667 Nonpathogen - hypothetical protein BL0039 1 None None None 23465823 Common - IclR-type transcriptional regulator BL1261 106 COG1414 IclR, Transcriptional regulator Transcription 23465968 Common - widely conserved hypothetical protein in upf0004 BL1408 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 23466329 Common hsdR HsdR-like protein of type I restriction modification system BL1785 123 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 23465371 Common glnE glutamate-ammonia-ligase adenylyltransferase BL0795 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 23465757 Common pepN aminopeptidase N BL1191 163 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 23465878 Common ftsI peptidoglycan synthetase; penicillin-binding protein 3 precursor BL1317 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 23464887 Common - probable ribonuclease PH BL0286 183 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 23465759 Common dapA dihydrodipicolinate synthase BL1193 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 23465599 Nonpathogen - hypothetical protein BL1033 1 None None None 23464961 Common atpE ATP synthase C chain BL0362 13 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 23466154 Common rpsM 30S ribosomal protein S13 BL1604 246 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 23465414 Nonpathogen - hypothetical protein BL0839 1 None None None 23466137 Common rplP 50S ribosomal protein L16 BL1586 219 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 23464996 Common - hypothetical protein BL0399 35 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 23464968 Nonpathogen - hypothetical protein BL0370 1 None None None 23464787 Nonpathogen - hypothetical protein BL0171 1 None None None 23466282 Nonpathogen - hypothetical protein BL1737 1 None None None 23465214 Common - hypothetical protein BL0631 32 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 23465881 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase BL1320 215 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 23464648 Nonpathogen - hypothetical protein BL0020 1 None None None 23466234 Nonpathogen - hypothetical membrane protein with unknown function BL1686 1 None None None 161485599 Common nrdR hypothetical protein BL1312 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 23465099 Common - hypothetical protein BL0509 22 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 23465420 Common - LacI-type transcriptional regulator BL0846 127 COG1609 PurR, Transcriptional regulators Transcription 23465911 Common pepP Xaa-Pro aminopeptidase I BL1350 215 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 23465385 Common - narrowly conserved hypothetical protein BL0810 41 None None None 23465569 Common - response regulator of two-component system BL1000 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23464922 Common pepC2 aminopeptidase C BL0321 16 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 23465161 Common - probable Hsp20-family heat shock chaperone BL0576 101 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 23465805 Nonpathogen - hypothetical protein with possible RecF domain BL1243 3 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 23465914 Common folC folylpolyglutamate synthase BL1353 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 23466074 Common - possible NagC/XylR-type transcriptional regulator BL1520 115 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23465636 Common pheS phenylalanyl-tRNA synthetase subunit alpha BL1067 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 23465662 Nonpathogen - hypothetical protein BL1093 1 None None None 23465132 Common - hypothetical transmembrane protein with unknown function BL0547 50 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 23464870 Common - ATP binding protein of ABC transporter similar to Vex1 (VexP1) of S. pneumoniae BL0268 14 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 23464750 Common - hypothetical protein BL0124 16 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23465634 Nonpathogen - hypothetical protein BL1065 1 None None None 23464894 Common - conserved hypothetical protein with duf177 BL0293 31 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 23466096 Common xynF possible extracellular exo-xylanase BL1544 38 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 23465086 Nonpathogen - hypothetical protein BL0496 1 None None None 23466176 Common - hypothetical protein in upf0074 BL1627 46 COG1959 COG1959, Predicted transcriptional regulator Transcription 23466273 Common proS prolyl-tRNA synthetase BL1728 244 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23466357 Nonpathogen - hypothetical protein BL1813 1 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 23465952 Common - narrowly conserved hypothetical protein BL1392 18 None None None 23465610 Common recN DNA repair protein RecN BL1043 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 23464825 Nonpathogen - hypothetical protein BL0212 1 None None None 23465876 Common - conserved hypothetical protein in upf0040 BL1315 135 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 23464833 Nonpathogen - hypothetical protein BL0226 1 None None None 23466026 Nonpathogen - hypothetical protein BL1470 1 None None None 23465671 Common - probable Na+ dependent transporter possibly for ileal bile acids BL1102 90 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 23464958 Common atpA F0F1 ATP synthase subunit alpha BL0359 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 23465453 Nonpathogen - hypothetical protein BL0879 1 None None None 23465322 Nonpathogen - hypothetical protein BL0745 1 None None None 23466000 Common - widely conserved hypothetical transmembrane protein with duf6 BL1444 140 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 23465007 Common silP copper-transporting ATPase BL0409 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 23465472 Common - hypothetical protein BL0898 61 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 23465287 Common pgk phosphoglycerate kinase BL0707 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 23465269 Nonpathogen - hypothetical protein BL0688 1 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 23465537 Common - hypothetical protein with duf143 BL0965 193 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 23466006 Common leuS leucyl-tRNA synthetase BL1450 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23465255 Common msiK ATP binding protein of ABC transporter for sugars BL0673 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 23465370 Common pyrB aspartate carbamoyltransferase catalytic subunit BL0794 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 23465608 Common - possible GntR-family transcriptional regulator BL1041a 145 COG1725 COG1725, Predicted transcriptional regulators Transcription 23465113 Common - possible permease protein of ABC transporter system BL0524 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23466251 Common xylA xylose isomerase BL1704 70 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 23464853 Common - hypothetical protein BL0250 7 None None None 23465068 Common - narrowly conserved hypothetical membrane protein BL0476 16 COG2246 COG2246, Predicted membrane protein Function unknown 23465592 Common mfd transcription-repair coupling factor BL1025 227 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 23465947 Common dppA2 DppA2 BL1386 194 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 23464849 Common - probable integrase/recombinase BL0245 47 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 23466213 Common thyA thymidylate synthase BL1665 140 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 23466016 Common - hypothetical protein BL1460 11 COG2253 COG2253, Uncharacterized conserved protein Function unknown 23465978 Common - hypothetical protein in sigma 54 modulation protein / S30ea ribosomal protein family BL1418 62 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 23465521 Common - narrowly conserved hypothetical protein BL0948 105 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 23465767 Common - narrowly conserved hypothetical protein with duf54 BL1200 42 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 23464920 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase BL0319 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 23464975 Nonpathogen - hypothetical protein BL0378 1 None None None 23465567 Common - possible transcriptional regulator BL0998 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 23466007 Common - hypothetical protein with C-terminal helix hairpin helix domain like that in ComE BL1451 104 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 23466194 Common - possible histidine kinase sensor of two component system BL1646 54 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 23465888 Common - alpha-mannosidase BL1327 52 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 23466340 Common - possible inositol monophosphatase BL1796 176 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 23465222 Nonpathogen - hypothetical protein BL0639 1 None None None 23465176 Common - hypothetical transmembrane protein with unknown function BL0591 22 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 23464722 Common - hypothetical protein BL0096 7 None None None 23464912 Common lemA LemA-like protein BL0311 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 23465273 Nonpathogen - hypothetical protein BL0692 1 None None None 23465363 Common - narrowly conserved hypothetical protein BL0787 6 None None None 23465247 Common - hypothetical protein BL0665 3 None None None 23466145 Common rplF 50S ribosomal protein L6 BL1595 236 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 23464757 Common pip hypothetical protein with similarity to pip phage infection protein of L. lactis BL0137 31 COG1511 COG1511, Predicted membrane protein Function unknown 23466299 Common - possible glutamate--cysteine ligase BL1755 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 23465319 Common helY probable helicase BL0742 124 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 23465279 Common - hypothetical myosin-like protein with unknown function BL0699 21 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 23465504 Common - possible transport protein BL0931 50 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 23465069 Nonpathogen - hypothetical protein BL0477 11 None None None 23465728 Common - pantothenate kinase BL1162 104 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 23465312 Common - hypothetical protein BL0734 5 None None None 23466144 Common rpsH 30S ribosomal protein S8 BL1594 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 23464677 Common - ATP binding protein of ABC transporter BL0049 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 23465351 Common - narrowly conserved hypothetical protein BL0775 18 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 23466203 Common gpm phosphoglyceromutase BL1656 176 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 23466123 Common rplM 50S ribosomal protein L13 BL1571 221 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 23466303 Common - hypothetical protein with possible nucleotidyltransferase domain BL1759 7 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 23465495 Nonpathogen - hypothetical protein BL0922 1 None None None 23465657 Common - possible MerR-type transcriptional regulator BL1088 12 COG0789 SoxR, Predicted transcriptional regulators Transcription 23464674 Nonpathogen - narrowly conserved hypothetical protein BL0046 3 COG0778 NfnB, Nitroreductase Energy production and conversion 23464745 Common - hypothetical protein BL0119 47 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 23464909 Common iunH inosine-uridine preferring nucleoside hydrolase BL0308 85 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 23466051 Common - hypothetical protein BL1494 4 None None None 23464862 Common bgaB beta-galactosidase I BL0259 40 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 23464630 Common groEL chaperonin GroEL BL0002 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 23465412 Nonpathogen - hypothetical protein BL0837 2 None None None 23465034 Common ftsY FtsY signal recognition particle BL0436 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 23464689 Common - protein similar to YcbI of B. subtilis BL0062 14 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 23465985 Nonpathogen - hypothetical protein BL1427 1 None None None 23465402 Nonpathogen - hypothetical protein BL0827 1 None None None 23465286 Common - narrowly conserved hypothetical protein BL0706 47 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 23464657 Common - recombination factor protein RarA BL0029 247 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 23465769 Common ppp probable phosphoprotein phosphatase BL1202 79 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 23465957 Common acn aconitate hydratase BL1397 222 COG1048 AcnA, Aconitase A Energy production and conversion 23465392 Common - hypothetical protein BL0817 2 None None None 23465847 Common proB gamma-glutamyl kinase BL1285 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 23465483 Common - possible ATP-dependent RNA helicase BL0909 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 23464666 Common - conserved protein with hydroxyacid dehydrogenase catalytic domain BL0038 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 23465796 Common - possible Etk-like tyrosine kinase involved in Eps biosynthesis BL1229 178 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 23464915 Common pstC probable phosphate permease protein of ABC transporter system BL0314 222 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 23465263 Common - conserved hypothetical transport protein BL0681 149 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23465841 Common - hypothetical protein with unknown or transport function BL1279 113 COG0679 COG0679, Predicted permeases General function prediction only 23466104 Nonpathogen - hypothetical protein BL1551 1 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 23465869 Common ldh2 lactate dehydrogenase BL1308 168 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 23466041 Common - hypothetical protein BL1485 5 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 23466220 Common - possible cyclopropane-fatty-acyl-phospholipid synthase BL1672 145 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 23465624 Common thiS hypothetical protein BL1055a 12 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 23465758 Common - widely conserved hypothetical protein with metallo-beta-lactamase domain BL1192 164 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 23465349 Nonpathogen - hypothetical protein BL0773 1 None None None 23466185 Nonpathogen - hypothetical protein BL1637 1 None None None 23466048 Common - hypothetical protein BL1491 3 None None None 23466010 Common - hypothetical protein with possible DNA binding function BL1454 24 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 23465522 Common - narrowly conserved hypothetical protein BL0949 15 None None None 23465502 Common - histidine kinase sensor of two-component system BL0929 85 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 23465713 Common dnaG DNA primase BL1147 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 23466122 Common malQ1 4-alpha-glucanotransferase BL1570 113 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 23464989 Common - possible transcriptional regulatory protein with low similarity to response regulators BL0392 197 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23464931 Common rpmB 50S ribosomal protein L28 BL0330 98 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 23464714 Common - narrowly conserved hypothetical transmembrane protein BL0088 15 COG4243 COG4243, Predicted membrane protein Function unknown 23465344 Common - hypothetical protein BL0768 14 None None None 23465065 Nonpathogen - hypothetical protein BL0473 1 None None None 23465434 Common - probable conserved integral membrane protein with CBS domain BL0860 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 23465168 Common - hypothetical protein with FHA domain BL0583 63 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 23466204 Common - response regulator of two-component system BL1657 191 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 23465744 Common - probable solute binding protein of ABC transporter system BL1178 145 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23465190 Nonpathogen - hypothetical protein BL0605 1 None None None 23465071 Common pepD dipeptidase BL0479 24 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 23466293 Common - possible NAD(P)H oxidoreductase BL1749 69 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 23464976 Common - hypothetical protein BL0379 2 None None None 23464702 Common - permease of ABC transporter system for amino acids BL0075 168 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 23465513 Common safC probable methyltransferase BL0940 48 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 23464840 Nonpathogen - hypothetical protein BL0233 14 COG2327 WcaK, Uncharacterized conserved protein Function unknown 23465439 Common tnsR possible tRNA/rRNA methyltransferase BL0865 117 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 23465905 Common nagA N-acetylglucosamine-6-phosphate deacetylase BL1344 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 23465691 Common purD phosphoribosylamine--glycine ligase BL1123 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 23466069 Common - possible phospholipase/carboxylesterase BL1514 30 COG0400 COG0400, Predicted esterase General function prediction only 23465785 Common snoP probable lipoate protein ligase BL1217 80 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 23464819 Common - possible glycosyltransferase BL0205 142 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23465693 Common - hypothetical protein with similarity to orf7 exopolysaccharide biosynthesis protein of S. mutans BL1125 18 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 23465303 Common - conserved hypothetical protein with Hit domain BL0725 96 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 23465199 Common ahpC alkyl hydroperoxide reductase C22 protein BL0615 210 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 23464945 Common ddlA D-alanine--D-alanine ligase BL0345 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 23465233 Nonpathogen - hypothetical protein BL0650 1 None None None 23466017 Common - hypothetical protein BL1461 6 None None None 23466263 Common - ATP binding protein of ABC transporter for branched-chain amino acids BL1718 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23466338 Common - probable Aaa-family ATPase BL1794 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 23465054 Common - narrowly conserved hypothetical protein with duf24 BL0458 151 COG1733 COG1733, Predicted transcriptional regulators Transcription 23466328 Common - hypothetical protein with possible DNA binding domain associated with typeI restriction-modification system BL1784 53 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 23465877 Common - widely conserved hypothetical protein in upf0117 BL1316 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 23464960 Common - F0F1 ATP synthase subunit B BL0361 30 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 23466318 Common - LacI-type transcriptional regulator BL1774 119 COG1609 PurR, Transcriptional regulators Transcription 23464900 Common - ATP binding protein of ABC transporter BL0299 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 23464886 Common - widely conserved hypothetical protein in Ham1 family BL0285 227 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 23465180 Nonpathogen - hypothetical protein BL0595 1 None None None 23465863 Common glnA2 glutamine synthetase 2 BL1302 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 23465102 Common - 3-oxoacyl-[acyl-carrier protein] reductase BL0512 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 23464789 Common pepC1 aminopeptidase C BL0173 15 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 23465972 Common pgsA3 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase BL1412 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 23465643 Common pdhD dihydrolipoamide dehydrogenase BL1074 235 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 23464864 Common - sugar transport system permease protein BL0261 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23464791 Common - probable AraC/XylS-type transcriptional regulator BL0175 128 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 23465552 Common - possible pyrophosphate-releasing NTPase in MutT family BL0983 95 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 23466038 Nonpathogen - hypothetical protein BL1482 1 None None None 23466225 Common - ATP-binding protein of ABC transporter system BL1677 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 23465778 Common galK galactokinase BL1210 97 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 23464671 Common - possible fused ATP binding protein and permease of ABC transporter BL0043 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 23466323 Common - phage family integrase BL1779 102 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23465560 Common - hypothetical protein in upf0038 BL0991 199 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 23465109 Common dnaK molecular chaperone DnaK BL0520 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 23466330 Common metK S-adenosylmethionine synthetase BL1786 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 23465128 Common - LacI-type transcriptional regulator BL0543 126 COG1609 PurR, Transcriptional regulators Transcription 23464761 Common - possible solute binding protein of ABC transporter BL0141 18 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23466268 Common orn oligoribonuclease BL1723 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 23465707 Nonpathogen - hypothetical protein BL1139 1 None None None 23465979 Common secA preprotein translocase subunit SecA BL1419 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 23465829 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase BL1267 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 23465822 Common - hypothetical protein BL1260 6 None None None 23466244 Nonpathogen - hypothetical protein BL1697 1 None None None 23464773 Common - narrowly conserved hypothetical protein BL0157 53 None None None 23464775 Common dinD DNA-damage-inducible protein of Escherichia coli BL0159 19 None None None 23465579 Common - hypothetical protein with FtsK/SpoIIIE domain BL1010 129 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 23465995 Common - narrowly conserved hypothetical protein similar to Mycobacterium tuberculosis RV2699C BL1437 19 None None None 23465617 Common - hypothetical protein BL1050 19 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 23465891 Common - probable solute-binding protein of ABC transporter system BL1330 93 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23465927 Common infC translation initiation factor If-3 BL1366 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 23465572 Common - hypothetical protein with phosphoribosylpyrophosphate transferase domain and similarity to OrfS annotated as putative ComF protein BL1003 24 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 23465366 Common pyrK probable dihydroorotate dehydrogenase electron transfer subunit BL0790 83 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 23465494 Nonpathogen - hypothetical protein BL0921 1 None None None 23464640 Common - hypothetical protein weakly similar to putative transcriptional regulator from Streptomyces BL0012 10 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 23464705 Common metC cystathionine beta-lyase BL0078 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 23465336 Common - amino acid permease BL0758 165 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 23464865 Common - solute binding protein of ABC transporter system BL0262 82 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23464850 Common - probable integrase/recombinase BL0246 92 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23464802 Common - exo-alpha-L-arabinofuranosidase II BL0187 20 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 23466008 Common - conserved hypothetical transmembrane protein related to ComA BL1452 105 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 23465323 Common - hypothetical protein with possible regulatory function BL0746 21 COG0789 SoxR, Predicted transcriptional regulators Transcription 23465221 Common dnaN DNA polymerase III subunit beta BL0638 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 23466099 Common pnpA polynucleotide phosphorylase/polyadenylase BL1546 236 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 23466210 Common - hypothetical protein with C-terminal similarity to p60 invasion-associated protein of Listeria BL1663 127 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 23465708 Common - possible transport protein BL1140 42 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 23465248 Nonpathogen - hypothetical protein with helix turn helix motif BL0666 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 23465889 Common - alpha-mannosidase BL1328 52 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 23466095 Common xynD endo-1,4-beta-xylanase D BL1543 24 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 23464717 Common - hypothetical protein BL0091 7 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 23465037 Common pepDB dipeptidase BL0439 23 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 23465652 Common - excinuclease ABC subunit A-like protein BL1083 236 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 23465620 Common - hypothetical protein in metal-dependent hydrolase family BL1053 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 23465844 Common rplU 50S ribosomal protein L21 BL1282 207 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 23465355 Common sipY probable signal peptidase I-2 BL0779 193 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 23465272 Common - narrowly conserved protein with unknown function BL0691 47 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 23464634 Common - histidine kinase sensor of two-component system BL0006 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 23464984 Nonpathogen - hypothetical protein BL0387 1 None None None 23464846 Common - probable integrase/recombinase BL0240 47 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 23465428 Nonpathogen - hypothetical protein BL0854 1 None None None 23465386 Nonpathogen - hypothetical protein BL0811 1 None None None 23465145 Common - hypothetical transmembrane protein with unknown function BL0560 73 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 23465318 Nonpathogen - hypothetical protein BL0741 2 COG2378 COG2378, Predicted transcriptional regulator Transcription 23464723 Common ispC 1-deoxy-D-xylulose 5-phosphate reductoisomerase BL0097 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 23465240 Common ksgA dimethyladenosine transferase BL0657 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 23465079 Nonpathogen - hypothetical protein BL0489 1 None None None 23464799 Common - large protein with C-terminal homology to alpha-arabinofuranosidase II BL0184 17 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 23465006 Common - narrowly conserved hypothetical protein BL0408 100 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 161485601 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase BL1132 199 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 23465589 Common - hypothetical protein BL1021 6 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 23465016 Common prsA1 ribose-phosphate pyrophosphokinase BL0418 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 23465471 Common pncA probable pyrazinamidase/nicotinamidase BL0897 93 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 23465538 Common - hypothetical protein BL0966 126 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 23464878 Common rnhB ribonuclease HII BL0276 173 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 23465902 Common - possible sugar kinase BL1341 158 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23465149 Common - modification methylase Sau3AI BL0564 107 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 23466218 Common - widely conserved hypothetical protein with methyltransferase domain BL1670 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 23465668 Common rpsG 30S ribosomal protein S7 BL1099 247 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 23466157 Common rplQ 50S ribosomal protein L17 BL1607 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 23466001 Common - narrowly conserved hypothetical protein BL1445 13 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 23465157 Common - hypothetical membrane protein with unknown function BL0572 9 None None None 23465809 Common - possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the fumarylacetoacetate hydrolase family BL1247 177 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 23464737 Common - hypothetical metabolite transport protein possibly for a sugar BL0111 118 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 23465112 Common - possible xylosidase or glucosidase BL0523 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 23465479 Common - hypothetical protein in Pho-4 inorganic transporter family BL0905 166 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 23464925 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase BL0324 193 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 23465098 Common - hypothetical protein possibly involved in adherence BL0508 148 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 23464885 Common - FemAB-like protein possibly involved in interpeptide bridge formation in peptidoglycan BL0284 17 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 23465919 Nonpathogen - hypothetical protein BL1358 1 None None None 23464668 Nonpathogen - narrowly conserved hypothetical protein BL0040 1 COG2314 XynA, Predicted membrane protein Function unknown 23466061 Common pyrH uridylate kinase BL1505 220 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 23465237 Common pcnA probable RNA nucleotidyltransferase BL0654 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 23465564 Common troB ATP binding protein of ABC transporter BL0995 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 23465633 Common argC N-acetyl-gamma-glutamyl-phosphate reductase BL1064 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 23466138 Common rpmC 50S ribosomal protein L29 BL1588 110 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 23465547 Common lacZ LacZ BL0978 67 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 23465663 Common - hypothetical protein BL1094 81 COG2855 COG2855, Predicted membrane protein Function unknown 23464999 Common - possible acetyltransferase BL0401 45 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 23464897 Common ilvB acetolactate synthase 1 catalytic subunit BL0296 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 23464871 Common - ABC-type transporter similar to Vex3 (VexP3) of S. pneumoniae BL0269 10 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 23465394 Nonpathogen - hypothetical protein BL0819 1 None None None 23464811 Common - hypothetical protein BL0196 22 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 23466071 Common - probable NhaP-type Na(+)/H(+) exchanger BL1516 99 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 23466049 Common - hypothetical protein with similarity to the Par protein of Bifidobacterium breve plasmid pcibb1 BL1492 55 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 23465087 Nonpathogen - hypothetical protein BL0497 1 None None None 23466272 Nonpathogen - hypothetical protein BL1727 1 None None None 23464824 Common - probable glycerol-3-phosphate cytidylyltransferase BL0210 100 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 23465430 Common pntB NAD(P) transhydrogenase subunit beta BL0856 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 23464834 Common rmlA glucose-1-phosphate thymidylyltransferase BL0227 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 23465311 Common sucD succinyl-CoA synthetase subunit alpha BL0733 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 23465675 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase BL1107 186 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 23464942 Common - possible permease of ABC transporter BL0342 177 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 23466281 Common - possible helicase BL1736 134 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 23466306 Nonpathogen - hypothetical protein BL1762 1 None None None 23464751 Common - narrowly conserved hypothetical membrane protein BL0125 20 COG1295 Rbn, Predicted membrane protein Function unknown 23466298 Common - long hypothetical protein BL1754 65 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 23465124 Common - probable integrase/recombinase BL0538 205 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23464938 Common aspA aspartate ammonia-lyase BL0338 230 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 23465116 Common - probable LacI-type transcriptional regulator BL0528 125 COG1609 PurR, Transcriptional regulators Transcription 23465898 Common - narrowly conserved hypothetical protein with possible isomerase function BL1337 36 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 23464964 Common metA homoserine O-succinyltransferase BL0365 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 23465735 Common - probable permease of ABC transporter system for sugars BL1169 167 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23465680 Common - probable LysR-type transcriptional regulator BL1112 186 COG0583 LysR, Transcriptional regulator Transcription 23465733 Common - LacI-type transcriptional regulator BL1167 126 COG1609 PurR, Transcriptional regulators Transcription 23466313 Common - conserved hypothetical protein with acetyl transferase (GnaT) domain BL1769 31 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 23466090 Common fas Fas BL1537 210 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 23464649 Common gluA ATP-binding protein of ABC transporter for glutamate BL0021 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 23466193 Common - response regulator of two-component system BL1645 180 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 23466027 Nonpathogen - hypothetical protein BL1471 1 None None None 23465013 Common ssb single-strand DNA-binding protein BL0415 168 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 23465045 Common - possible TetR-type transcriptional regulator BL0448 34 COG1309 AcrR, Transcriptional regulator Transcription 23465948 Common dppB probable permease protein of ABC-transporter for peptides BL1387 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23465802 Nonpathogen - hypothetical protein BL1236 1 None None None 23465910 Common - hypothetical protein containing MutT-like domain BL1349 52 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 23466222 Common - probable glycosyltransferase BL1674 158 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23466348 Common - hypothetical protein BL1804 6 None None None 23465831 Common - probable LysR-type transcriptional regulator BL1269 140 COG0583 LysR, Transcriptional regulator Transcription 23465042 Common - hypothetical protein BL0445 12 COG4905 COG4905, Predicted membrane protein Function unknown 23465421 Common hemN probable oxygen-independent coproporphyrinogen III oxidase BL0847 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 23465976 Common - RecX-like protein BL1416 11 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 23466346 Common - hypothetical protein BL1802 6 None None None 23466341 Common - hypothetical proteasome-associated protein BL1797 16 None None None 23466039 Common - narrowly conserved hypothetical protein BL1483 11 None None None 23465825 Common leuD isopropylmalate isomerase small subunit BL1263 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 23464754 Common - narrowly conserved hypothetical protein BL0128 15 None None None 23466310 Common - ATP-binding protein of ABC transporter BL1766 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 23465712 Common - pyridoxine biosynthesis protein BL1146 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 23465618 Common tyrS tyrosyl-tRNA synthetase BL1051 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 23465029 Common dnaB replicative DNA helicase BL0431 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 23465457 Nonpathogen - hypothetical protein BL0883 1 None None None 23466245 Common - possible MarR-type transcriptional regulator BL1698 3 COG1846 MarR, Transcriptional regulators Transcription 23465343 Common - hypothetical protein with acyl transferase domain BL0766 20 COG3981 COG3981, Predicted acetyltransferase General function prediction only 23464930 Common recG ATP-dependent DNA helicase BL0329 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 23466334 Common - possible alpha beta hydrolase BL1790 44 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 23466324 Common - truncated type I restriction system specificity protein BL1780 55 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 23466295 Common xseA exodeoxyribonuclease VII large subunit BL1751 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 23464776 Nonpathogen - possible MarR-type transcriptional regulator BL0160 4 COG1846 MarR, Transcriptional regulators Transcription 23466308 Common - fragment of beta-glucosidase BL1764 23 None None None 23465721 Common metB cystathionine gamma-synthase BL1155 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 23464774 Common - very narrowly conserved hypothetical protein BL0158 28 COG3889 COG3889, Predicted solute binding protein General function prediction only 23465965 Common - conserved hypothetical protein with MutT type domain BL1405 133 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 23466223 Common - hypothetical integral membrane protein in upfo118 BL1675 61 COG0628 PerM, Predicted permease General function prediction only 23464669 Common - hypothetical protein BL0041 51 COG1950 COG1950, Predicted membrane protein Function unknown 23465565 Common - possible permease of ABC transporter system BL0996 188 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 23464951 Common - hypothetical protein BL0352 6 None None None 23465408 Common gltD glutamate synthase subunit beta BL0833 216 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 23464818 Nonpathogen - hypothetical protein BL0204 1 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 23465899 Common - narrowly conserved hypothetical protein BL1338 19 COG3538 COG3538, Uncharacterized conserved protein Function unknown 23464798 Common - possible endo-1,5-alpha-L-arabinosidase BL0183 17 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 23466147 Common rpsE 30S ribosomal protein S5 BL1597 245 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 23465698 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit BL1130 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 23466101 Nonpathogen - hypothetical protein BL1548 1 None None None 23466262 Common - ATP binding protein of ABC transporter for branched-chain amino acids BL1717 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 23465368 Common pyrC dihydroorotase BL0792 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 23465450 Common aroQ 3-dehydroquinate dehydratase BL0876 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 23465238 Common - hypothetical protein BL0655 4 None None None 23464726 Common recO DNA repair protein RecO BL0100 63 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 23465448 Common pyrG CTP synthetase BL0874 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 23465998 Common - possible peptidyl-prolyl cis-trans isomerase BL1442 111 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 23464917 Common - response regulator of two-component system BL0316 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23466337 Common - hypothetical conserved transmembrane protein in the DedA family BL1793 161 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 23464901 Common - possible amidotransferase BL0300 137 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 23465306 Common ruvA probable holliday junction DNA helicase RuvA BL0728 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 23465856 Common acyP possible acylphosphatase BL1294 137 COG1254 AcyP, Acylphosphatases Energy production and conversion 23465755 Nonpathogen - hypothetical protein BL1189 2 None None None 23465393 Nonpathogen - hypothetical protein BL0818 1 None None None 23465853 Common rplA 50S ribosomal protein L1 BL1291 222 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 23465838 Common - hypothetical protein with MutT domain BL1276 173 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 23465621 Common - conserved hypothetical protein with rhodanese-like domain BL1053a 70 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 23466202 Common - probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase BL1655 73 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 23466085 Nonpathogen - hypothetical protein BL1532 1 None None None 23465027 Common - possible cobyric acid synthase CobQ BL0429 47 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 23464837 Common - hypothetical transmembrane protein possibly involved in polysaccharide biosynthesis BL0230 38 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 23465166 Common - hypothetical protein with alpha beta hydrolase domain at C-terminus BL0581 73 COG2267 PldB, Lysophospholipase Lipid metabolism 23465467 Common - hypothetical protein with probable helix turn helix motif BL0893 50 COG3655 COG3655, Predicted transcriptional regulator Transcription 23465925 Common - hypothetical protein BL1364 3 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 23464879 Common lepB probable signal peptidase I BL0277 178 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 23465256 Nonpathogen - possible cell surface protein with gram positive anchor domain BL0674 2 None None None 23464805 Common - sugar permease of ABC transporter system BL0190 166 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23466184 Common serS seryl-tRNA synthetase BL1635 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 23465486 Nonpathogen - hypothetical protein BL0912 1 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 23465469 Common - narrowly conserved hypothetical protein BL0895 14 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 23465644 Common - narrowly conserved hypothetical transmembrane protein BL1075 19 None None None 23465144 Nonpathogen - hypothetical protein BL0559 1 None None None 23466238 Common glkA glucokinase BL1691 173 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23465882 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase BL1321 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 23464990 Common nth endonuclease III BL0393 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 23465072 Nonpathogen - hypothetical protein BL0480 1 None None None 23465066 Common - hypothetical protein with possible phosphoglycerate mutase domain BL0474 41 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 23465292 Common - bifunctional HTH-domain containing protein/aminotransferase BL0712 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 23464681 Common mrp hypothetical protein with duf059 and 4Fe-4S iron sulfur cluster binding domain BL0053 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 23464859 Nonpathogen - hypothetical protein BL0256 1 None None None 23465763 Common - large hypothetical protein BL1197 18 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 23465460 Common rpsD 30S ribosomal protein S4 BL0886 229 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 23465780 Common - probable DeoR-type transcriptional regulator BL1212 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 23466292 Common fadD4 probable long-chain-fatty-acid--CoA ligase; long-chain acyl-CoA synthetase BL1748 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 23465879 Nonpathogen - hypothetical protein possibly involved in cell wall formation BL1318 1 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 23465779 Common galT1 galactose-1-phosphate uridylyltransferase BL1211 77 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 23465655 Common - hypothetical protein BL1086 8 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 23466044 Nonpathogen - hypothetical protein BL1487 1 None None None 23465437 Common - hypothetical protein in Hit family BL0863 232 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 23465909 Common - ATP binding protein of ABC transporter BL1348 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 23466129 Common rpsJ 30S ribosomal protein S10 BL1577 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 23466054 Common - hypothetical protein BL1498 3 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 23464847 Common - probable integrase/recombinase BL0241 205 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23465984 Common idsA bifunctional short chain isoprenyl diphosphate synthase BL1426 239 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 23465799 Nonpathogen - hypothetical protein BL1233 1 None None None 23465505 Common - possible ATP binding protein of ABC transporter BL0932 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23465868 Common hflX GTP-binding protein BL1307 232 COG2262 HflX, GTPases General function prediction only 23465150 Common - possible restriction endonuclease BL0565 43 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 23465415 Common - hypothetical protein BL0840 6 None None None 23464676 Common - probable aminotransferase BL0048 204 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 23465215 Nonpathogen - hypothetical protein BL0632 1 None None None 23465788 Common - narrowly conserved hypothetical protein BL1220 22 COG4850 COG4850, Uncharacterized conserved protein Function unknown 23465932 Common - widely conserved hypothetical protein in ParA family BL1370 232 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 23465264 Common - protein probably involved in xylan degradation; possible xylan esterase BL0682 67 COG0657 Aes, Esterase/lipase Lipid metabolism 23465285 Common - hypothetical protein BL0705 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 23464658 Common - response regulator of two-component system BL0030 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 23465503 Common - response regulator of two-component system BL0930 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 23464692 Common efp elongation factor P BL0065 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 23464730 Common - possible permease protein of ABC transporter system BL0104 156 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 23466254 Common xylB xylulose kinase BL1709 162 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 23466021 Common - hypothetical protein BL1465 7 None None None 23465937 Common nadB L-aspartate oxidase BL1375 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 23465188 Common - narrowly conserved hypothetical protein BL0603 26 COG2966 COG2966, Uncharacterized conserved protein Function unknown 23465842 Common dapE dipeptidase BL1280 192 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 23464983 Common - probable phage-family integrase/recombinase protein BL0386 208 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 23465524 Common pfl formate acetyltransferase BL0951 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 23466077 Common msmG sugar permease of ABC transporter system BL1523 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23465429 Common - hypothetical protein BL0855 39 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 23465478 Common - conserved hypothetical protein with duf47 BL0904 66 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 23465170 Common - possible phosphoprotein phosphatase BL0585 130 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 23464742 Common glyS glycyl-tRNA synthetase BL0116 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 23465598 Common nadD nicotinic acid mononucleotide adenyltransferase BL1032 182 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 23465470 Common - hypothetical protein BL0896 45 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 23465019 Common - narrowly conserved hypothetical protein possibly involved in xylan degradation BL0421 11 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 23465317 Common ugpA probable UTP-glucose-1-phosphate uridylyltransferase BL0739 6 COG4284 COG4284, UDP-glucose pyrophosphorylase Carbohydrate transport and metabolism 23465787 Common ptrB protease II BL1219 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 23465669 Common rpsL 30S ribosomal protein S12 BL1100 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 23464827 Nonpathogen - hypothetical protein BL0214 1 None None None 23465696 Common fur probable metal uptake regulator similar to ferric uptake regulator protein BL1128 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 23466002 Common - hypothetical protein BL1446 16 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 23465395 Nonpathogen - hypothetical protein BL0820 1 None None None 23464796 Common - similar to alpha-arabinofuranosidase I BL0181 24 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 23464973 Common - hypothetical protein with similarity to putative maturation protease of prophage CP-9 33CE BL0376 5 COG3740 COG3740, Phage head maturation protease General function prediction only 23466018 Common - hypothetical protein with similarity to ZK593.8 protein of C. elegans BL1462 59 COG3177 COG3177, Uncharacterized conserved protein Function unknown 23465602 Common thrC threonine synthase BL1036 132 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 23465571 Common - hypothetical protein with similarity to ImpA of Salmonella involved in UV protection and mutation BL1002 117 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 23465506 Common cysD O-acetylhomoserine (thiol)-lyase BL0933 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 23465945 Nonpathogen - hypothetical protein BL1383 1 None None None 23464906 Common rpsP 30S ribosomal protein S16 BL0305 112 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 23465043 Common - hypothetical membrane protein with similarity to phage infection protein BL0446 31 COG1511 COG1511, Predicted membrane protein Function unknown 23465026 Common - hypothetical protein BL0428 3 COG3937 COG3937, Uncharacterized conserved protein Function unknown 23464860 Common - possible arabinogalactan endo-beta-galactosidase or galactanase BL0257 21 COG3867 COG3867, Arabinogalactan endo-1,4-beta-galactosidase Carbohydrate transport and metabolism 23465249 Nonpathogen - hypothetical protein BL0667 1 None None None 23465031 Common glnD protein-pII; uridylyltransferase BL0433 120 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 23464940 Common - hypothetical protein BL0340 26 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 23465290 Common ldh1 L-lactate dehydrogenase BL0710 151 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 23465514 Common - hypothetical protein BL0941 158 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 23465081 Nonpathogen - hypothetical protein BL0491 4 None None None 23465348 Nonpathogen - hypothetical protein BL0772 1 None None None 23465488 Common - narrowly conserved hypothetical protein BL0914 11 COG4260 COG4260, Putative virion core protein (lumpy skin disease virus) Function unknown 23466227 Common - hypothetical secreted protein with D-Ala-D-Ala carboxypeptidase 3 (S13) domain BL1679 84 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 23466211 Common - widely conserved protein in universal stress protein family BL1664 82 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 23464680 Common ligA LigA BL0052 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 23465220 Common recF recombination protein RecF BL0637 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 23465146 Common - hypothetical protein BL0561 5 COG0456 RimI, Acetyltransferases General function prediction only 23465365 Common pyrD dihydroorotate dehydrogenase BL0789 187 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 23465235 Common - hypothetical protein BL0652 5 None None None 23465401 Common glgA possible glycosyltransferase BL0826 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 23465324 Common garA possible signal transduction protein BL0747 71 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 23465734 Common bga beta-galactosidase I BL1168 41 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 23466164 Common nusA transcription elongation factor NusA BL1615 223 COG0195 NusA, Transcription elongation factor Transcription 23465601 Common glyA serine hydroxymethyltransferase BL1035 227 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 23464965 Common - hypothetical protein with helix turn helix motif BL0367 8 COG1396 HipB, Predicted transcriptional regulators Transcription 23465681 Common - hypothetical protein in aldo/keto reductase 2 family BL1113 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 23465496 Common - hypothetical protein BL0923 7 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 23465115 Common malQ 4-alpha-glucanotransferase BL0527 118 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 23465897 Common - probable LacI-type transcriptional regulator BL1336 124 COG1609 PurR, Transcriptional regulators Transcription 23466192 Common galE1 UDP-glucose 4-epimerase BL1644 231 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 23466347 Nonpathogen - hypothetical protein BL1803 1 None None None 23465120 Common shiA transmembrane transport protein possibly for shikimate BL0532 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464933 Common - narrowly conserved hypothetical protein BL0332 74 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 23464966 Nonpathogen - hypothetical protein BL0368 1 None None None 23465679 Common - possible Na(+)/H(+) antiporter BL1111 50 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 23465151 Common - hypothetical protein with 30% N-terminal similarity to glycosyltransferase BL0566 36 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23466349 Nonpathogen - hypothetical protein BL1805 1 None None None 23464642 Common - creatinine amidohydrolase; creatininase BL0014 85 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 23464641 Common proP proline/betaine transporter BL0013 169 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23465720 Common - hypothetical protein BL1154 20 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 23465123 Common spl sucrose phosphorylase BL0536 52 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 23465839 Common - ATP-binding protein of ABC transporter system BL1277 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23464863 Common - sugar transport system permease protein BL0260 161 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23465736 Common - probable permease of ABC transporter system for sugars BL1170 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 23465236 Common - hypothetical protein with possible C-terminal pyrophosphate-releasing NTPase domain BL0653 65 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 23466265 Common - conserved protein in the Sua5/YciO/YrdC family BL1720 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 23464803 Common - solute binding protein of ABC transporter system BL0188 99 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 23465205 Common - narrowly conserved hypothetical protein with duf45 BL0621 104 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 23466062 Common frr ribosome recycling factor BL1506 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 23465413 Common - LacI-type transcriptional regulator BL0838 128 COG1609 PurR, Transcriptional regulators Transcription 23464883 Common - FemAB-like protein possibly involved in interpeptide bridge formation in peptidoglycan BL0282 13 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 23465310 Common sucC succinyl-CoA synthetase beta chain BL0732 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 23465546 Nonpathogen - hypothetical protein BL0977 1 None None None 23464896 Common rncS ribonuclease III BL0295 215 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 23464956 Common atpD F0F1 ATP synthase subunit beta BL0357 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 23465818 Common - IS1630em protein E1 BL1256 42 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23465130 Common kup possible low-affinity potassium uptake system BL0545 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 23465762 Common - widely conserved ATP-dependent DNA helicase; Rep-like protein BL1196 225 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 23466219 Common galE2 UDP-glucose 4-epimerase BL1671 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 23466024 Nonpathogen - hypothetical protein BL1468 1 None None None 23464810 Nonpathogen - hypothetical protein with possible glutamine amidotransferase domain BL0195 3 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 23466072 Common mesJ possible cytidine and deoxycytidylate deaminase BL1517 206 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 23465674 Common purT phosphoribosylglycinamide formyltransferase 2 BL1105 195 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 23465632 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein BL1063 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 23464998 Nonpathogen - narrowly conserved hypothetical protein BL0400a 1 None None None 23465451 Common aroB bifunctional shikimate kinase -3-dehydroquinate synthase protein BL0877 214 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 23466280 Nonpathogen - hypothetical protein BL1735 4 COG2378 COG2378, Predicted transcriptional regulator Transcription 23464635 Common cspB cold shock protein BL0007 159 COG1278 CspC, Cold shock proteins Transcription 23464752 Nonpathogen - hypothetical protein BL0126 1 None None None 23465177 Common - narrowly conserved hypothetical protein BL0592 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 23465990 Common lhr ATP-dependent helicase II BL1432 189 COG1201 Lhr, Lhr-like helicases General function prediction only 23465950 Common dppD DppD BL1390 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 23466253 Nonpathogen - hypothetical protein BL1707 1 None None None 23465966 Common - possible integral membrane protein with duf6 BL1406 110 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 23465021 Common - sugar permease of ABC transporter system BL0423 169 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 23464797 Common - possible endo-1,5-alpha-L-arabinosidase BL0182 15 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 23465409 Common gltB glutamate synthase [NADPH] large subunit; NADPH-gogat BL0834 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 23466102 Common rplJ 50S ribosomal protein L10 BL1549 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 23465803 Nonpathogen - hypothetical protein BL1237 1 None None None 23464957 Common atpG F0F1 ATP synthase subunit gamma BL0358 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 23465710 Common - probable multiple substrate aminotransferase (MsaT) containing domain of GntR family BL1144 227 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 23465997 Common relA RelA BL1439 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 23465619 Nonpathogen - hypothetical protein BL1052 1 None None None 23465545 Common lacS galactoside symporter BL0976 66 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 23465645 Common glnA1 glutamine synthetase 1 BL1076 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 23464884 Common - FemAB-like protein possibly involved in interpeptide bridge formation in peptidoglycan BL0283 10 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 23465711 Common - conserved hypothetical protein in sno glutamine amidotransferase family BL1145 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 23465001 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A BL0403 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 23465862 Common - narrowly conserved hypothetical protein BL1301 31 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 23465627 Common argG argininosuccinate synthase BL1058 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 23465551 Common glgX probable glycogen operon protein GlgX BL0982 158 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 23465709 Common - L-asparaginase precursor BL1142 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 23465771 Common rpoC DNA-directed RNA polymerase subunit beta' BL1204 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 23464739 Common thiD phosphomethylpyrimidine kinase BL0113 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 23465970 Common - hypothetical protein with C-terminal similarity to cell (division) filamentation protein Fic BL1410 27 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 23464858 Common - dehydrogenase or reductase protein BL0255 169 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 23465440 Common glgC glucose-1-phosphate adenylyltransferase BL0866 182 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 23465187 Common opuE possible sodium/proline symporter BL0602 166 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 23465824 Common leuC isopropylmalate isomerase large subunit BL1262 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 23464777 Nonpathogen - hypothetical protein BL0161 1 None None None 23465103 Common - possible acyl-CoA reductase BL0513 14 None None None 23465890 Common - alpha-mannosidase BL1329 51 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 23465458 Common - hypothetical protein in the phosphoglycerate mutase family BL0884 143 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 23464932 Common - probable PfkB family carbohydrate (sugar) kinase BL0331 42 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 23466294 Common xseB exonuclease VII, small subunit BL1750 18 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 23466327 Common hsdS HsdS specificity protein of type I restriction-modification system BL1783 82 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 23465749 Common ftsE FtsE-like ATP binding protein involved in cell division BL1183 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 23465699 Common badC NADPH:quinone oxidoreductase or alcohol dehydrogenase BL1131 170 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 23465330 Common hisE phosphoribosyl-ATP pyrophosphatase BL0752 55 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 23466336 Common serB probable phosphoserine phosphatase BL1792 156 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 23464950 Common - hypothetical protein with marginal similarity to thioredoxin BL0350 59 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 23466174 Nonpathogen - hypothetical protein BL1625 1 None None None 23466033 Nonpathogen - hypothetical protein BL1477 1 None None None 23466311 Common - ABC transporter, ATP-binding transmembrane protein BL1767 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 23464943 Common - possible permease protein of ABC transporter system BL0343 70 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 23465938 Common nadC nicotinate-nucleotide pyrophosphorylase BL1376 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 23465611 Common ppnK inorganic polyphosphate/ATP-NAD kinase BL1044 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 23464907 Common - hypothetical protein BL0306 64 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 23465722 Common cbsSV cystathionine beta-synthase BL1156 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 23465271 Common - hypothetical protein with glucose/ribitol dehydrogenase family signature BL0690 225 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 23465367 Common pyrF orotidine 5'-phosphate decarboxylase BL0791 71 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 23465832 Common - hypothetical transmembrane protein possibly involved in uptake or efflux BL1270 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464740 Common thiE/thiC thiamine biosynthesis protein BL0114 220 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 23465931 Common - large protein with N-terminal similarity to ATP binding protein of ABC transporter BL1369 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 23465354 Common hutM histidine permease BL0778 171 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 23465901 Common - probable transcriptional repressor in the Rok (NagC/XylR) family BL1340 139 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 23465218 Common gyrB DNA gyrase subunit B BL0635 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 23464785 Nonpathogen - hypothetical protein BL0169 1 None None None 23464747 Common - hypothetical protein BL0121 26 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 23465305 Common ruvC Holliday junction resolvase BL0727 192 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 23466146 Common rplR 50S ribosomal protein L18 BL1596 223 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 23464724 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase BL0098 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 23465867 Common - conserved hypothetical protein possibly in upfoo20 BL1306 81 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 23465265 Common pacL1 cation-transporting ATPase PacL BL0683 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 23465400 Common - probable ATP binding protein of ABC transporter BL0825 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 23465028 Common - narrowly conserved hypothetical protein with Mur ligase domain BL0430 67 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 23465574 Common - hypothetical protein BL1005 17 None None None 23465449 Common - hypothetical protein in the M20/M25/M40 peptidase family BL0875 40 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 23465760 Common dapB dihydrodipicolinate reductase BL1194 179 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 23465284 Common aroE probable shikimate 5-dehydrogenase BL0704 108 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 23465793 Common trxA2 thioredoxin BL1226 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 23465493 Common - possible efflux transporter protein BL0920 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 23464982 Common - holin-like protein similar to orf of bacteriophage BK5-T BL0385 4 None None None 23464650 Common gluB glutamate-binding protein of ABC transporter system BL0022 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23466141 Common rplX 50S ribosomal protein L24 BL1591 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 23465410 Common - hypothetical protein with similarity to transcriptional repressors BL0835 77 COG1609 PurR, Transcriptional regulators Transcription 23466109 Nonpathogen - hypothetical protein BL1557 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 23464693 Common nusB NusB antitermination protein BL0066 140 COG0781 NusB, Transcription termination factor Transcription 23465983 Common pknA2 probable serine-threonine protein kinase BL1425 156 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 23465347 Nonpathogen - hypothetical protein BL0771 1 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 23464679 Nonpathogen - hypothetical protein BL0051 1 None None None 23465855 Common - similar to xylulose kinase BL1293 183 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 23465212 Common - AsnC-type transcriptional regulator BL0629 145 COG1522 Lrp, Transcriptional regulators Transcription 23466275 Common pepO belongs to peptidase family M13 BL1730 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 23465468 Common - hypothetical protein with alpha beta hydrolase domain possibly an esterase BL0894 101 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 23465018 Common - probable extracellular protein possibly involved in xylan or arabinan degradation BL0420 26 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 23465908 Common - probable permease of ABC transporter for peptides BL1347 197 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 23465515 Common nhaA probable sodium/proton antiporter BL0942 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 23465485 Common - hypothetical protein possibly in the phosphoglycerate mutase family BL0911 30 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 23465080 Common - hypothetical protein BL0490 7 None None None 23465597 Common - possible B-hexosaminidase BL1031 164 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 23465158 Nonpathogen - hypothetical protein BL0573 1 None None None 23466086 Common - hypothetical protein with possible biotin protein ligase catalytic domain BL1533 137 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 23464851 Common - hypothetical protein with possible low molecular weight protein-tyrosine-phosphatase domain BL0248 86 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 23466183 Common - conserved hypothetical protein with possible diacylglycerol kinase-type catalytic domain BL1634 59 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 23465067 Common - hypothetical membrane protein with unknown function BL0475 26 None None None 23465654 Common - hypothetical protein BL1085 18 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 23465466 Common pbuX xanthine/uracil permease BL0892 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 23464704 Common - probable solute-binding protein for glutamate/aspartate ABC transporter system BL0077 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 23464716 Nonpathogen - hypothetical protein BL0090 1 None None None 23466050 Nonpathogen - possible WhiB-like transcription factor BL1493 2 None None None 23465182 Common glgP glycogen phosphorylase BL0597 135 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 23465073 Common - DNA polymerase III subunit delta' BL0483 215 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 23466128 Common - hypothetical protein BL1576 6 None None None 23466239 Common - ATP binding protein of ABC transporter for pentoses BL1692 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 23465010 Common ptsH histidine-containing phosphocarrier protein (Hpr protein) of Pts transport system BL0412 108 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 23466053 Common - narrowly conserved hypothetical protein in M23/M37 peptidase family BL1497 21 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 23466067 Common dcd deoxycytidine triphosphate deaminase BL1512 156 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 23465929 Common rplT 50S ribosomal protein L20 BL1367 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 23466139 Common rpsQ 30S ribosomal protein S17 BL1589 228 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 23465036 Common - probable glycosyltransferase BL0438 190 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 23465291 Common - conserved hypothetical protein with duf13 BL0711 104 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only