Streptomyces coelicolor A3(2), complete genome NC_003888 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 21225744 Common - secreted protein SCO7476 9 None None None 21225487 Common - hypothetical protein SCO7210 33 COG5637 COG5637, Predicted integral membrane protein Function unknown 21220125 Common - hypothetical protein SCO1629 9 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21218825 Common - transcriptional repressor protein SCO0275 137 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21220093 Common - two-component sensor SCO1596 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 21220848 Common - hypothetical protein SCO2381 6 None None None 21224695 Nonpathogen - integral membrane protein SCO6383 1 None None None 21225305 Common - secreted alpha-amylase SCO7020 25 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21219734 Common - sugar-phosphate isomerase SCO1224 115 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 21222366 Common - seryl-tRNA synthetase SCO3961 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 21222383 Common - TetR-family transcriptional regulator SCO3979 26 COG1309 AcrR, Transcriptional regulator Transcription 21225378 Nonpathogen - membrane protein SCO7096 1 None None None 21224711 Nonpathogen - hypothetical protein SCO6403 1 None None None 21221778 Common - DNA-binding protein SCO3348 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 21220040 Common - hypothetical protein SCO1540 7 None None None 21221988 Nonpathogen - hypothetical protein SCO3570 1 None None None 21223453 Common - transcriptional regulatory protein SCO5082 32 COG1309 AcrR, Transcriptional regulator Transcription 21220327 Common - enoyl-CoA hydratase/isomerase SCO1838 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21218690 Common - beta-lactamase SCO0130 72 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21221361 Common - amino acid permease SCO2914 156 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 21221024 Nonpathogen - hypothetical protein SCO2565 1 None None None 21225261 Common - GntR-family regulatory protein SCO6974 126 COG2188 PhnF, Transcriptional regulators Transcription 21218973 Common - secreted protein SCO0431 16 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21219344 Common - gntR-family transcriptional regulator SCO0823 105 COG1725 COG1725, Predicted transcriptional regulators Transcription 21220194 Common - transcriptional regulator SCO1699 53 COG1309 AcrR, Transcriptional regulator Transcription 21223185 Nonpathogen - hypothetical protein SCO4807 1 None None None 21223442 Common - hydroxylacyl-CoA dehydrogenase SCO5070 3 None None None 21225599 Common - regulatory protein SCO7324 32 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21222168 Common - two component system sensor kinase SCO3757 102 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21219735 Common - osmoprotectant transporter SCO1225 136 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220987 Common - acetyltransferase SCO2526 58 COG0456 RimI, Acetyltransferases General function prediction only 21225040 Common - transcriptional regulator SCO6746 156 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21225637 Common - oxidoreductase SCO7363 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21226073 Common - TetR-family transcriptional regulator SCO7824 17 COG1309 AcrR, Transcriptional regulator Transcription 21225079 Common - oxidoreductase SCO6786 59 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21221744 Common - hypothetical protein SCO3313 12 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 21219687 Common - dihydroxy-acid dehydratase SCO1176 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 21225722 Common - secreted protein SCO7453 33 None None None 21225434 Common - ketol-acid reductoisomerase SCO7154 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 21220512 Common - hypothetical protein SCO2031 8 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21224755 Common - dehydrogenase SCO6449 61 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21218814 Common - oxidoreductase SCO0263 94 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21223380 Nonpathogen - septum site-determining protein SCO5007 1 None None None 21220706 Common - hypothetical protein SCO2235 46 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 21225090 Common - ATP/GTP binding protein SCO6797 30 COG2229 COG2229, Predicted GTPase General function prediction only 21221734 Nonpathogen - integral membrane protein SCO3302 1 None None None 21221600 Common - hypothetical protein SCO3163 6 None None None 21225604 Common - long-chain-fatty-acid-CoA ligase SCO7329 216 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 21224565 Common - hypothetical protein SCO6244 23 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 21220306 Common - hypothetical protein SCO1817 21 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 21222428 Common - tetR family transcriptional regulatory protein SCO4025 23 COG1309 AcrR, Transcriptional regulator Transcription 21223778 Common - transcriptional regulator SCO5418 32 COG1309 AcrR, Transcriptional regulator Transcription 21225857 Common - oxidoreductase SCO7594 185 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21220224 Nonpathogen - hypothetical protein SCO1730 3 None None None 21220240 Common - secreted serine protease SCO1746 11 None None None 21224332 Nonpathogen - secreted protein SCO5995 1 None None None 21223737 Common - chitinase two-component response regulator SCO5377 197 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219751 Common - DNA-binding protein SCO1242 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 21225729 Nonpathogen - lipoprotein SCO7460 1 None None None 21226024 Common - hypothetical protein SCO7770 32 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 21219635 Nonpathogen - secreted protein SCO1121 4 COG3652 COG3652, Predicted outer membrane protein Function unknown 21223482 Common - GTP-binding protein SCO5111 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 21223231 Common sdhB succinate dehydrogenase iron-sulfur subunit SCO4855 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 21218688 Nonpathogen - hypothetical protein SCO0128 1 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 21221262 Common - drug efflux protein SCO2812 21 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21223394 Nonpathogen - lipoprotein SCO5021 1 None None None 21225567 Common - dehydrogenase SCO7290 76 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21222815 Common - hypothetical protein SCO4427 3 None None None 21223069 Common - hypothetical protein SCO4689 10 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21221467 Common - transport protein SCO3024 103 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 21224447 Common - hypothetical protein SCO6120 13 None None None 21222084 Common - heat chock protein SCO3670 229 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 21225629 Common - hypothetical protein SCO7355 54 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 21224339 Common - DNA-binding protein SCO6003 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 21225552 Nonpathogen - hypothetical protein SCO7275 2 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 21224723 Common - oxidoreductase SCO6416 39 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21225254 Common - beta-ketoadipyl-CoA thiolase SCO6967 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21224152 Common - hypothetical protein SCO5807 3 None None None 21225766 Common - racemase SCO7499 43 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 21223164 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein SCO4785 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 21224861 Common - respiratory chain oxidoreductase SCO6559 192 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 21218787 Common - oxidoreductase SCO0234 209 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21226094 Nonpathogen - hypothetical protein SCO7846 1 None None None 21224760 Common - ABC transporter ATP-binding protein SCO6454 246 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21223052 Common - lysR-family regulatory protein SCO4671 171 COG0583 LysR, Transcriptional regulator Transcription 32141273 Common - two-component system sensor SCO5779 204 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21225295 Common - hypothetical protein SCO7009 57 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221756 Common - hypothetical protein SCO3325 40 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21223439 Common - carboxylesterase SCO5067 83 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 21225973 Nonpathogen - acetyltransferase SCO7714 1 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21221565 Common - phosphoenolpyruvate carboxylase SCO3127 118 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 21224273 Nonpathogen - hypothetical protein SCO5935 1 None None None 21221705 Nonpathogen - DNA-binding protein SCO3272 1 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 21222937 Common - bi-functional transferase/deacetylase SCO4554 226 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21225998 Common - hydrolase SCO7739 31 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 21222660 Common - hypothetical protein SCO4267 5 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21223896 Common - ATP-GTP binding protein SCO5541 31 COG2229 COG2229, Predicted GTPase General function prediction only 21219209 Nonpathogen - hypothetical protein SCO0679 1 None None None 21225737 Common - phenylacetate-CoA ligase SCO7469 108 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 21222520 Common - integral membrane protein SCO4121 17 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 21223612 Common - hypothetical protein SCO5245 23 COG5207 UBP14, Isopeptidase T Posttranslational modification, protein turnover, chaperones 21219804 Nonpathogen - hypothetical protein SCO1297 4 None None None 21222790 Nonpathogen - hypothetical protein SCO4400 1 COG5373 COG5373, Predicted membrane protein Function unknown 21218660 Common - IS1652 transposase SCO0091 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219667 Nonpathogen - hypothetical protein SCO1154 1 None None None 21218621 Nonpathogen - hypothetical protein SCO0042 4 None None None 21220566 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase SCO2086 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 21220117 Common - glycine betaine transport ATP-binding protein SCO1621 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 21221298 Common - hypothetical protein SCO2848 20 COG4702 COG4702, Uncharacterized conserved protein Function unknown 21219015 Common - ABC transporter protein, integral membrane subunit SCO0475 128 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 21224998 Common - transcriptional regulator SCO6704 76 COG1846 MarR, Transcriptional regulators Transcription 21225946 Common - cytochrome P450 SCO7686 78 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21219520 Common - tetR-family transcriptional regulator SCO1003 27 COG1309 AcrR, Transcriptional regulator Transcription 21222810 Common - tetR-family transcriptional regulatory protein SCO4421 10 COG1309 AcrR, Transcriptional regulator Transcription 21223484 Common - BldKB, ABC transport system lipoprotein SCO5113 158 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21219862 Common - iron sulphur protein (secreted protein) SCO1356 48 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 21223863 Nonpathogen - hypothetical protein SCO5507 1 None None None 21223282 Common - RNA polymerase sigma factor SCO4908 150 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225443 Common - transferase SCO7163 54 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 21225864 Common - amidase SCO7601 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 21219584 Common - marR-family transcriptional regulator SCO1069 53 COG1846 MarR, Transcriptional regulators Transcription 21222574 Nonpathogen - hypothetical protein SCO4177 2 None None None 21223498 Common - hypothetical protein SCO5128 9 None None None 21220483 Common - secreted protein SCO2001 22 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 21222171 Common - secreted protein SCO3760 7 None None None 21219142 Nonpathogen - integral membrane protein SCO0609 3 None None None 21225461 Common - branched amino acid transport system ATP-binding protein SCO7182 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 21224839 Common - conserved DNA-binding protein SC5C722c SCO6537 6 None None None 21220033 Nonpathogen - hypothetical protein SCO1533 5 None None None 21225873 Nonpathogen - hypothetical protein SCO7611 21 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 21220204 Common - integral membrane transport protein SCO1709 14 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225730 Common - hydrolase SCO7461 10 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 21224617 Common - hypothetical protein SCO6298 62 COG3246 COG3246, Uncharacterized conserved protein Function unknown 21224891 Common - secreted protein SCO6591 3 None None None 21218597 Common - Na+/H+ antiporter SCO0015 103 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 21222124 Nonpathogen - small membrane protein SCO3711 1 None None None 32141102 Common - dehydrogenase SCO0189 17 COG3349 COG3349, Uncharacterized conserved protein Function unknown 21222807 Common - oxidase SCO4418 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 21219864 Common - LysR-family transcriptional regulator SCO1358 177 COG0583 LysR, Transcriptional regulator Transcription 21220722 Nonpathogen - hypothetical protein SCO2252 4 None None None 21224471 Common - hypothetical protein SCO6145 11 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 21219975 Common fmt methionyl-tRNA formyltransferase SCO1473 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 21223930 Common - hypothetical protein SCO5574 134 COG1733 COG1733, Predicted transcriptional regulators Transcription 21219313 Common - integral membrane protein SCO0791 10 COG4129 COG4129, Predicted membrane protein Function unknown 21222196 Common - integral membrane protein SCO3785 10 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21223399 Common - hypothetical protein SCO5026 15 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21225645 Common - hypothetical protein SCO7371 31 None None None 21220974 Common - hypothetical protein SCO2513 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 21219316 Common - ROK family transcriptional regulator SCO0794 131 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21220239 Common - two-component system response regulator SCO1745 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221245 Common - lacI-family transcriptional regulatory protein SCO2794 129 COG1609 PurR, Transcriptional regulators Transcription 21223013 Common - hypothetical protein SCO4631 17 COG1403 McrA, Restriction endonuclease Defense mechanisms 21220804 Common - integral membrane transport protein SCO2336 149 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225178 Nonpathogen - hypothetical protein SCO6887 1 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 32141241 Common - integral membrane protein SCO4548 7 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21220230 Common - marR-family transcriptional regulator SCO1736 13 COG1846 MarR, Transcriptional regulators Transcription 21223095 Common rpsN 30S ribosomal protein S14 SCO4715 211 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 21223449 Nonpathogen - hypothetical protein SCO5078 2 None None None 21223900 Nonpathogen - hypothetical protein SCO5545 1 None None None 21220281 Common - hypothetical protein SCO1789 49 COG4198 COG4198, Uncharacterized conserved protein Function unknown 21220570 Common - cell division protein SCO2090 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21225758 Common - oxidoreductase SCO7490 188 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21219152 Common - hypothetical protein SCO0620 81 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 21220889 Nonpathogen - secreted protein SCO2424 2 None None None 21223374 Nonpathogen - integral membrane protein SCO5001 1 None None None 21225237 Common - hypothetical protein SCO6950 6 None None None 21222152 Common - histidine kinase SCO3740 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 21222511 Common - hypothetical protein SCO4111 177 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 21223086 Common rpsS 30S ribosomal protein S19 SCO4706 240 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 21226037 Common - hypothetical protein SCO7786 17 None None None 21225805 Common - hypothetical protein SCO7540 106 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 21224534 Common - hypothetical protein SCO6210 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 21221554 Common - hypothetical protein SCO3115 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21226069 Nonpathogen - hypothetical protein SCO7820 1 None None None 21220257 Common - hypothetical protein SCO1765 22 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 21219660 Common - lipoprotein SCO1146 10 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 21222976 Common - hypothetical protein SCO4593 98 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21225477 Nonpathogen - membrane protein SCO7199 1 None None None 21221684 Nonpathogen - excisionase SCO3251 1 None None None 21223903 Common - hypothetical protein SCO5548 24 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21225963 Common - TetR-family transcriptional regulator SCO7704 23 COG1309 AcrR, Transcriptional regulator Transcription 21220184 Common - phosphotransferase SCO1689 58 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 21223313 Common - hypothetical protein SCO4939 4 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 21221655 Nonpathogen - secreted protein SCO3220 1 None None None 32141229 Nonpathogen - hypothetical protein SCO4187 1 None None None 21222930 Nonpathogen - lipoprotein SCO4546 1 None None None 21219725 Common - integral membrane protein SCO1215 32 COG3336 COG3336, Predicted membrane protein Function unknown 21221228 Common - acetyl/propionyl CoA carboxylase alpha subunit SCO2777 233 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 21225577 Common - hypothetical protein SCO7301 116 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21220630 Common - secreted protein SCO2153 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 21222537 Common - phosphate ABC transport system ATP-binding protein SCO4139 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 21222553 Common - two-component system sensor SCO4155 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21222767 Common - serine-threonine protein kinase SCO4377 134 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21219387 Common - probable ECF-family sigma factor SCO0866 82 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 32141185 Common - oxidoreductase SCO2942 71 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 21223071 Common - hypothetical protein SCO4691 4 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 21219786 Common - ATP/GTP-binding protein SCO1278 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 21225543 Common - 3-oxoacyl-[acyl-carrier protein] reductase SCO7266 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221375 Common - asnC-family transcriptional regulator SCO2928 151 COG1522 Lrp, Transcriptional regulators Transcription 21219321 Common - hypothetical protein SCO0799 6 None None None 21225163 Nonpathogen - hypothetical protein SCO6872 1 None None None 21224308 Common - hypothetical protein SCO5971 80 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21224688 Nonpathogen - integral membrane protein SCO6376 1 None None None 21219826 Common - hypothetical protein SCO1320 33 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 21223109 Common rplQ 50S ribosomal protein L17 SCO4730 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 21218771 Common - nitrate reductase beta chain NarH2 SCO0217 146 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 21222554 Common - two-component systen response regulator SCO4156 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21223791 Nonpathogen - integral membrane protein SCO5432 3 None None None 21225070 Common - beta-lactamase SCO6777 62 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21225171 Common - lipoprotein SCO6880 7 None None None 21224925 Common - hypothetical protein SCO6628 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220182 Common - hypothetical protein SCO1687 19 COG2149 COG2149, Predicted membrane protein Function unknown 21221676 Common - myo-inositol phosphate synthase SCO3243 50 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 21223724 Common - serine hydroxymethyltransferase SCO5364 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 21223939 Common - ammonium transporter SCO5583 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 21225680 Common - binding-protein dependent transport protein SCO7410 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21221213 Common - secreted tripeptidyl aminopeptidase SCO2761 7 None None None 21222486 Common - hypothetical protein SCO4084 18 None None None 21219696 Nonpathogen - hypothetical protein SCO1185 2 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 21225498 Common - polyketide synthase SCO7221 28 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 32141319 Common - binding protein dependent transport protein SCO7012 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21220149 Common - hypothetical protein SCO1653 21 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 21219519 Nonpathogen - hypothetical protein 2SCG215c SCO1002 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 21223044 Common - hypothetical protein SCO4663 2 None None None 21223241 Common - ECF sigma factor SCO4866 150 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225007 Common - transcriptional regulator SCO6713 126 COG1609 PurR, Transcriptional regulators Transcription 21224400 Common - secreted solute binding protein SCO6070 61 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21226052 Nonpathogen - hypothetical protein SCO7800 3 None None None 21220542 Common - ABC transport ATP-binding subunit SCO2061 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21219240 Nonpathogen - oxidoreductase SCO0714 5 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21220907 Common - carrier protein (membrane protein) SCO2443 18 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 21225371 Common - probable two-component system sensor kinase SCO7089 113 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220923 Common - hypothetical protein SCO2459 2 None None None 21225210 Common - hypothetical protein SCO6922 19 None None None 21226062 Nonpathogen - insertion element transposase SCO7812 5 None None None 21225468 Common - hypothetical protein SCO7189 10 None None None 21220549 Common - hypothetical protein SCO2069 30 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21220670 Common - integral membrane protein SCO2197 12 COG1714 COG1714, Predicted membrane protein/domain Function unknown 21219265 Common - hydrolase SCO0740 203 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21222823 Common - hypothetical protein SCO4435 14 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21221302 Nonpathogen - membrane protein SCO2852 1 None None None 21218619 Common - glycosyl transferase SCO0040 57 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 21223475 Common - hypothetical protein SCO5104 68 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21220112 Common - hypothetical protein SCO1615 126 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 21223239 Common - ECF sigma factor SCO4864 37 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225316 Common - beta-D-xylosidase SCO7031 149 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21221009 Nonpathogen - lipoprotein SCO2550 1 None None None 21224494 Common - regulatory protein SCO6169 21 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21225384 Nonpathogen - hypothetical protein SCO7102 1 None None None 21219456 Nonpathogen - hypothetical protein SCO0937 3 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21222203 Common - methionyl-tRNA synthetase SCO3792 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21224112 Common - hypothetical protein SCO5766 15 None None None 21222056 Common - two-component system sensor kinase SCO3641 116 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21224184 Common - transcriptional regulator SCO5840 125 COG1802 GntR, Transcriptional regulators Transcription 21221090 Common - superoxide dismutase [Fe-Zn] SCO2633 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 21221291 Common - secreted protein SCO2841 12 None None None 21218611 Nonpathogen - hypothetical protein SCO0032 1 None None None 21222029 Common - RNA polymerase sigma factor SCO3613 14 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21224463 Common - transmembrane protein SCO6136 6 None None None 21224418 Common - antibiotic resistance rRNA adenine methyltransferase SCO6089 202 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 21222033 Nonpathogen - hypothetical protein SCO3617 4 None None None 21220612 Common - secreted protein SCO2135 139 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21221487 Common - hypothetical protein SCO3044 60 COG1316 LytR, Transcriptional regulator Transcription 21219465 Common - integral membrane protein SCO0947 9 None None None 21225217 Common - hypothetical protein SCO6930 8 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 21223569 Common - hypothetical protein SCO5200 27 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21224435 Common - acyl-CoA dehydrogenase SCO6106 141 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21224507 Common - transferase SCO6183 26 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 21220689 Common - secreted protein SCO2217 6 None None None 21220713 Common - TetR-family transcriptional regulator SCO2243 37 COG1309 AcrR, Transcriptional regulator Transcription 21221454 Common - lipoprotein SCO3011 15 None None None 21224045 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase SCO5696 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 21225833 Common - hypothetical protein SCO7569 84 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 21224885 Common sucC succinyl-CoA synthetase subunit beta SCO6585 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 21220249 Nonpathogen - hypothetical protein 2SCI3409 SCO1756 1 None None None 21221611 Common - exodeoxyribonuclease (secreted protein) SCO3174 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 21219593 Common - lacI-family transcriptional regulator SCO1078 127 COG1609 PurR, Transcriptional regulators Transcription 21223355 Nonpathogen - hypothetical protein SCO4982 1 None None None 21224570 Common - 3-oxoacyl-[acyl-carrier-protein] reductase SCO6249 218 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21218590 Nonpathogen - hypothetical protein SCO0008 1 None None None 21219682 Common - xylose repressor SCO1171 150 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21224478 Common - small hydrophobic protein (membrane protein) SCO6152 7 None None None 21220942 Nonpathogen - hypothetical protein SCO2479 1 None None None 21221042 Nonpathogen - membrane protein SCO2583 1 None None None 21224596 Common - epoxide hydrolase SCO6277 99 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225298 Common - sugar-binding lipoprotein SCO7013 69 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21220954 Common - oxidoreductase SCO2491 201 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21221908 Common - secreted sugar-binding protein SCO3484 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21221036 Common - hypothetical protein SCO2577 191 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 21224070 Common - regulator, BldB SCO5723 6 None None None 21219527 Common - integral membrane transport protein SCO1010 128 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21222733 Nonpathogen - hypothetical protein SCO4341 1 COG2403 COG2403, Predicted GTPase General function prediction only 21220912 Common - hypothetical protein SCO2448 4 None None None 21224093 Common - regulatory protein SCO5747 97 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21224887 Common - dehydrogenase SCO6587 211 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21223894 Common - hypothetical protein SCO5539 14 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21221323 Common - oxidoreductase SCO2874 117 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221309 Common - hypothetical protein SCO2859 72 COG1695 COG1695, Predicted transcriptional regulators Transcription 21220640 Common - two component sensor kinase SCO2166 71 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220759 Nonpathogen - hypothetical protein SCO2290 1 None None None 21225160 Common - hypothetical protein SCO6869 3 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21219228 Nonpathogen - hypothetical protein SCO0701 1 None None None 21223409 Common - hypothetical protein SCO5036 40 COG1695 COG1695, Predicted transcriptional regulators Transcription 21218618 Nonpathogen - hypothetical protein SCO0039 1 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 21222350 Common - cytochrome oxidase subunit I SCO3945 163 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 21219845 Common - hypothetical protein SCO1339 6 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 21221413 Common - cell division protein SCO2968 51 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 21222488 Common - amidophosphoribosyltransferase SCO4086 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 21220129 Nonpathogen - secreted protein SCO1633 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 21222289 Common - hypothetical protein SCO3882 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 21222626 Nonpathogen - lipoprotein SCO4231 1 None None None 21223366 Common - metal ion transport protein SCO4993 34 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 21223460 Common - actinorhodin polyketide synthase acyl carrier protein SCO5089 5 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21223677 Common - whiE protein VII SCO5314 4 None None None 21219575 Common - transcriptional repressor SCO1060 125 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21221088 Common - amino acid permease SCO2631 156 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 21224957 Common - glucose-6-phosphate 1-dehydrogenase SCO6661 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 21218844 Common - transmembrane efflux protein SCO0295 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221055 Common rplU 50S ribosomal protein L21 SCO2597 180 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 21223866 Common - dehydrogenase SCO5510 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 21225059 Common - hypothetical protein SCO6766 98 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 21222044 Common - adenylosuccinate synthetase SCO3629 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 21223760 Common - transport system kinase SCO5400 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 21223769 Common - hypothetical protein SCO5409 8 None None None 21222891 Common - hypothetical protein SCO4506 31 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 21221099 Common - hypothetical protein SCO2642 8 None None None 21221967 Common - anti-sigma factor SCO3548 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220130 Nonpathogen - small membrane protein SCO1634 1 None None None 32141145 Common - hypothetical protein SCO1511 31 COG4717 COG4717, Uncharacterized conserved protein Function unknown 21223877 Common - 3-isopropylmalate dehydrogenase SCO5522 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 21225426 Common - regulatory protein SCO7146 31 COG0640 ArsR, Predicted transcriptional regulators Transcription 21225356 Common - hypothetical protein SCO7073 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 21225845 Common - hypothetical protein SCO7581 29 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 21223201 Common - bifunctional protein (methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase) SCO4824 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 21224526 Nonpathogen - hypothetical protein SCO6202 1 None None None 21224827 Common - hypothetical protein SCO6525 103 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 21223560 Nonpathogen - hypothetical protein 2SC3B615 SCO5191 1 None None None 21223749 Common - hypothetical protein 2SC6G533 SCO5389 5 None None None 21224292 Common - chitinase (secreted protein) SCO5954 41 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 21219362 Common - oxidoreductase SCO0841 137 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223255 Common - polysaccharide biosynthesis related protein SCO4881 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 21223321 Common - nitrate reductase beta chain NarH3 SCO4948 153 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 21222501 Nonpathogen - hypothetical protein SCO4100 1 None None None 21222802 Common - araC family transcriptional regulatory protein SCO4413 129 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21225036 Common - ABC transporter ATP-binding protein SCO6742 240 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21221661 Common - two component system response regulator SCO3226 221 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225783 Common - integral membrane protein SCO7517 63 None None None 21221459 Common - integral membrane protein SCO3016 7 None None None 21219569 Nonpathogen - hypothetical protein SCO1053 1 None None None 21219840 Nonpathogen - hypothetical protein SCO1334 1 None None None 21219213 Common - hypothetical protein SCO0684 2 None None None 21220025 Common - sugar transferase SCO1525 224 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21224186 Common - hypothetical protein SCO5842 149 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 21225779 Common - secreted hydrolase SCO7513 15 None None None 21225677 Common - probable beta-galactosidase SCO7407 40 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 21224075 Nonpathogen - secreted protein SCO5728 1 None None None 21223916 Common ddl D-alanyl-alanine synthetase A SCO5560 211 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 21222065 Common pyrE orotate phosphoribosyltransferase SCO3650 99 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 21220001 Common - hypothetical protein SCO1500 136 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 21220783 Nonpathogen - hypothetical protein SCO2315 1 None None None 21218662 Common - noncomposite transposon transposase SCO0096 55 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220764 Common - hypothetical protein SCO2295 122 COG0789 SoxR, Predicted transcriptional regulators Transcription 21220894 Common - secreted protein SCO2429 8 None None None 21225123 Nonpathogen - hypothetical protein SCO6831 1 None None None 21224081 Common - ATP/GTP binding protein (membrane protein) SCO5734 183 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21220174 Common - transcriptional regulator SCO1678 89 COG2186 FadR, Transcriptional regulators Transcription 21221665 Common - CDA peptide synthetase II SCO3231 220 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21223246 Common - tetR-family transcriptional regulator SCO4871 38 COG1309 AcrR, Transcriptional regulator Transcription 21221911 Common - hydrolase SCO3487 11 None None None 21222452 Common - antibiotic binding protein SCO4049 58 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 21221396 Common - malate oxidoreductase SCO2951 202 COG0281 SfcA, Malic enzyme Energy production and conversion 21223646 Common - ATP-binding protein SCO5280 30 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 21219275 Common - regulatory protein SCO0751 95 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21218998 Nonpathogen - hypothetical protein SCO0457 14 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 21220647 Common - adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase SCO2173 126 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 21224107 Common - ATP-dependent DNA helicase SCO5761 198 COG1201 Lhr, Lhr-like helicases General function prediction only 21223584 Common - RNA polymerase sigma factor RpoE SCO5216 173 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225927 Common - hypothetical protein SCO7667 22 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 21218861 Common - transmembrane transport protein SCO0313 36 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21219474 Nonpathogen - hpothetical protein SCM1111 SCO0956 1 None None None 21225039 Common - hypothetical protein SCO6745 8 None None None 21223596 Common - acetyltransferase SCO5228 9 COG0456 RimI, Acetyltransferases General function prediction only 21225281 Common - protease SCO6995 37 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21222406 Nonpathogen - hypothetical protein 2SC10A707c SCO4003 1 None None None 21220008 Common - integral membrane protein SCO1507 18 COG4243 COG4243, Predicted membrane protein Function unknown 21225086 Common - probable aldehyde dehydrogenase SCO6793 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21218706 Common - transcriptional regulatory protein SCO0148 49 COG3655 COG3655, Predicted transcriptional regulator Transcription 21220843 Nonpathogen - hypothetical protein SCO2376 1 None None None 21223386 Nonpathogen - secreted protein SCO5013 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 21224365 Common - hypothetical protein SCO6033 5 None None None 21221008 Common - protease SCO2549 61 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 21225336 Common - hypothetical protein SCO7053 23 None None None 32141162 Common - glutamate-ammonia-ligase adenylyltransferase SCO2234 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 21219485 Common - reductase SCO0967 65 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 21224129 Common - two-component sensor SCO5784 68 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21218819 Nonpathogen - hypothetical protein SCO0268 1 None None None 21224545 Common - hypothetical protein SCO6223 111 COG1733 COG1733, Predicted transcriptional regulators Transcription 21218921 Common - conserved secreted protein SCO0378 25 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21220445 Common - hydrolase SCO1960 201 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21220139 Common - 20S proteasome alpha-subunit SCO1643 38 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 21220506 Common gltD glutamate synthase subunit beta SCO2025 218 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 21221202 Common - hypothetical protein SCO2750 43 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21222747 Common - hypothetical protein SCO4356 2 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21222329 Common - hypothetical protein SCO3923 10 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 21221893 Common - transposase SCO3469 44 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 21224166 Common - DNA topoisomerase IV subunit B SCO5822 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 21225265 Common - probable solute-binding lipoprotein SCO6979 73 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21222830 Common - hypothetical protein SCO4442 5 None None None 21224983 Common - hypothetical protein SCO6688 25 None None None 21222163 Nonpathogen - hypothetical protein SCO3751 1 None None None 21223849 Common - hypothetical protein SCO5493 18 None None None 21223389 Nonpathogen - integral membrane protein SCO5016 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 21221670 Common - hypothetical protein SCO3237 26 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 21225996 Nonpathogen - hypothetical protein SCO7737 1 None None None 21224685 Nonpathogen - integral membrane protein SCO6373 1 None None None 21220140 Common - 20S proteasome beta-subunit precursor SCO1644 51 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 21223500 Common - ABC transporter integral membrane protein SCO5130 26 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21219562 Common - metal transporter ATPase SCO1046 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 21223507 Nonpathogen - ATP-binding protein SCO5137 1 None None None 21221924 Common - binding protein dependent transport protein SCO3503 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21225960 Common - methyltransferase SCO7701 32 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 21222588 Nonpathogen - hypothetical protein SCO4192 2 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 21219985 Common - carbamoyl phosphate synthase small subunit SCO1484 232 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 21222850 Common - hypothetical protein SCO4463 8 None None None 21220752 Common - secreted esterase SCO2283 147 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21222180 Common - tetR family transcriptional regulatory protein SCO3769 28 None None None 32141326 Nonpathogen - hypothetical protein SCO7202 1 None None None 21222264 Common - hypothetical protein SCO3855 136 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 21224667 Common - two-component regulator SCO6354 208 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21218654 Nonpathogen - hypothetical protein SCO0085 2 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 21221200 Common - carbohydrate kinase SCO2748 121 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21224714 Nonpathogen - secreted protein SCO6406 2 None None None 21219717 Common - cytochrome P450 SCO1207 72 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21222840 Common - RNA polymerase sigma factor SCO4452 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 21223416 Common - hydrolase (membrane protein) SCO5043 43 COG2234 Iap, Predicted aminopeptidases General function prediction only 21223146 Common - regulatory protein SCO4767 19 None None None 21223781 Common - integral membrane protein SCO5421 7 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 21223296 Nonpathogen - integral membrane protein SCO4922 1 None None None 21225459 Common - hypothetical protein SCO7180 6 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 21222600 Common - glycosyltransferase SCO4204 151 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21219163 Nonpathogen - hypothetical protein SCO0631 1 None None None 21222671 Common - hypothetical protein SCO4278 103 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 21222527 Nonpathogen - hypothetical protein SCO4128 3 None None None 21220411 Common - hypothetical protein SCO1925 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 21226083 Common - hypothetical protein SCO7834 3 None None None 21220835 Common - hypothetical protein SCO2367 30 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21219914 Common - transmembrane transport protein SCO1411 211 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21219254 Nonpathogen - hypothetical protein SCO0729 7 None None None 32141307 Common - hypothetical protein SCO6580 11 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21219745 Common ureA urease subunit gamma SCO1236 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 21225134 Nonpathogen - hypothetical protein SCO6842 1 None None None 21219064 Common - probable oxidoreductase (secreted protein) SCO0529 51 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21220655 Common - dihydrolipoamide succinyltransferase SCO2181 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 21223834 Common - oligopeptide-binding lipoprotein SCO5477 186 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21218906 Common - racemase SCO0362 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 21220576 Common - hypothetical protein SCO2096 94 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 21222700 Common murQ N-acetylmuramic acid-6-phosphate etherase SCO4307 84 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 21223979 Common rpsB 30S ribosomal protein S2 SCO5624 218 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 21218646 Nonpathogen - hypothetical protein SCO0071 1 None None None 21219869 Nonpathogen - hypothetical protein SCO1364 1 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 21222042 Nonpathogen - hypothetical protein SCO3627 1 None None None 32141266 Common - delta-1-pyrroline-5-carboxylate dehydrogenase SCO5520 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 32141342 Common - hypothetical protein SCO7753 10 COG1846 MarR, Transcriptional regulators Transcription 21224749 Common - hypothetical protein SCO6443 24 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21223100 Common rpmD 50S ribosomal protein L30 SCO4720 125 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 21221519 Common - secreted protein SCO3078 14 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21224787 Common - efflux protein SCO6483 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220292 Common - two component response regulator SCO1801 225 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221715 Common cobH precorrin-8X methylmutase SCO3282 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 21222357 Nonpathogen - hypothetical protein SCO3952 1 None None None 21219102 Common - polyprenyl synthetase SCO0568 230 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 21221770 Common - hypothetical protein SCO3340 82 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21218764 Common - hypothetical protein SCO0210 70 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 21218980 Common - pyrrolidone-carboxylate peptidase SCO0438 57 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 21222874 Common - serine/threonine protein kinase SCO4488 141 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21225418 Common - hypothetical protein SCO7136 65 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21218759 Common - two-component sensor SCO0203 99 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21219290 Common - secreted beta-galactosidase SCO0766 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21225938 Common - metal transport integral membrane protein SCO7678 184 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21221500 Common - dipeptidase SCO3058 103 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 21222708 Common - homeostasis protein SCO4315 31 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 32141256 Common - integral membrane protein SCO5204 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 21219287 Common - oxidoreductase SCO0763 109 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 21221471 Common manB phosphomannomutase/phosphoglucomutase SCO3028 237 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 21220880 Common - secreted protein SCO2414 33 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 21221450 Common - hypothetical protein SCO3007 60 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 21221034 Nonpathogen - hypothetical protein SCO2575 1 COG1326 COG1326, Uncharacterized archaeal Zn-finger protein General function prediction only 21222251 Common - dioxygenase SCO3842 47 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 21223704 Nonpathogen - SpdC2 protein SCO5343 1 None None None 21221621 Common - ABC transporter integral membrane protein SCO3186 39 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21222291 Common - hypothetical protein SCO3884 72 COG1847 Jag, Predicted RNA-binding protein General function prediction only 21223179 Common - hypothetical protein SCO4801 13 None None None 32141142 Nonpathogen - hypothetical protein SCO1407 5 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 21224642 Nonpathogen - hypothetical protein SCO6328 1 None None None 21223715 Common - homoserine dehydrogenase SCO5354 187 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 21220995 Common - probable transmembrane transport protein SCO2536 115 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225771 Common - integral membrane binding-protein-dependent transport protein SCO7504 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21224120 Common - glutamate permease SCO5774 193 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 21225411 Common - hypothetical protein SCO7129 78 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21221996 Common - ion-transporting ATPase SCO3578 21 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 21224900 Common - transcriptional regulator SCO6600 38 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21220729 Common - membrane protein SCO2260 68 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 21222849 Common - integral membrane protein SCO4462 64 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 21225590 Common - probable RNA polymerase sigma factor SCO7314 215 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21219096 Common - integral membrane protein SCO0562 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 21223940 Common - PII uridylyl-transferase SCO5585 119 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 21222898 Nonpathogen - hypothetical protein SCO4513 1 None None None 21222941 Common - acetyltransferase SCO4558 69 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21222855 Nonpathogen - hypothetical protein SCO4468 1 None None None 21224801 Common - hypothetical protein SCO6498 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 21220494 Common - branched chain amino acid transport ATP-binding protein SCO2012 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 21219280 Common - ABC transporter SCO0756 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 21223949 Common - tRNA (guanine-N1)-methyltransferase SCO5594 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 21225396 Common - hypothetical protein SCO7114 12 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21218589 Nonpathogen - hypothetical protein SCO0007 1 None None None 21223465 Common - methyltransferase SCO5094 77 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 21223223 Common - D-alanyl-D-alanine carboxypeptidase SCO4847 147 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 21220336 Common cobD cobalamin biosynthesis protein SCO1847 144 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 21221593 Common - penicillin-binding protein (secreted protein) SCO3156 138 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21223428 Common - exodeoxyribonuclease VII small subunit SCO5055 18 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 21221527 Nonpathogen - lipoprotein SCO3086 1 None None None 21222224 Common - DNA-binding protein SCO3814 2 COG3617 COG3617, Prophage antirepressor Transcription 21219038 Nonpathogen - hypothetical protein SCO0500 1 None None None 21220919 Common - spermidine synthase SCO2455 125 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 21218656 Common - secreted protein SCO0087 22 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 21224197 Common - hypothetical protein SCO5853 41 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21222714 Nonpathogen - integral membrane protein SCO4322 1 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 21220815 Nonpathogen - integral membrane protein SCO2347 7 COG2119 COG2119, Predicted membrane protein Function unknown 21222991 Common - NADH dehydrogenase subunit NuoN2 SCO4608 204 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 21223165 Common - hypthetical protein SCD6318c SCO4786 6 None None None 21221975 Common - secretory protein SCO3556 149 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 21221727 Common - oxidoreductase SCO3295 50 COG0431 COG0431, Predicted flavoprotein General function prediction only 21222118 Common - ABC transporter membrane subunit SCO3705 183 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 21222455 Common - glucose 1-dehydrogenase SCO4052 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21219881 Common - lacI-family transcriptional regulatory protein SCO1376 128 COG1609 PurR, Transcriptional regulators Transcription 21223558 Nonpathogen - hypothetical protein 2SC3B613 SCO5189 1 None None None 21225066 Common - secreted peptidase SCO6773 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21222425 Common - glycosyl transferase SCO4022 111 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21223986 Common - traSA:integrase fusion protein SCO5633 108 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21221570 Common - trans-aconitate methyltransferase SCO3132 77 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 21224776 Common - coenzyme B12-dependent mutase SCO6472 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 21222379 Common - regulator SCO3975 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21219074 Common - probable sugar transporter membrane protein SCO0539 156 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21224628 Common - cytochrome P450 SCO6310 50 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21219120 Common - hypothetical protein SCO0587 9 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21225786 Common - integral membrane protein SCO7520 33 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 21220617 Common - transcriptional regulator SCO2140 44 COG1522 Lrp, Transcriptional regulators Transcription 21220162 Common - phosphatase SCO1666 71 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21220393 Common - secreted protein SCO1906 49 COG3211 PhoX, Predicted phosphatase General function prediction only 21225731 Common - integral membrane protein SCO7462 42 COG0730 COG0730, Predicted permeases General function prediction only 21220574 Common - regulatory protein SCO2094 175 COG0714 COG0714, MoxR-like ATPases General function prediction only 32141174 Common - hypothetical protein SCO2534 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21223821 Common - MerR-family transcriptional regulator SCO5463 133 COG0789 SoxR, Predicted transcriptional regulators Transcription 21224796 Common - hypothetical protein SCO6493 7 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21219472 Common - acetyltransferase SCO0954 35 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 21225103 Common - hypothetical protein SCO6810 26 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21219040 Nonpathogen - hypothetical protein SCO0502 1 None None None 21220523 Nonpathogen - hypothetical protein SCO2042 1 None None None 21223268 Nonpathogen - hypothetical protein 2SCK820c SCO4894 1 None None None 21225970 Common - two component system sensor kinase SCO7711 22 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21222442 Common - hypothetical protein 2SCD6005c SCO4039 6 None None None 21224932 Common - bacteriophage (phiC31) resistance gene pglY SCO6635 9 None None None 21224769 Common - hypothetical protein SCO6463 73 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21225180 Nonpathogen - hypothetical protein SCO6889 1 None None None 21221823 Common - hypothetical protein SCO3396 28 COG0627 COG0627, Predicted esterase General function prediction only 21223530 Common - hypothetical protein SCO5161 131 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 21224406 Common - dipeptidase SCO6076 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 21218738 Common - hypothetical protein SCO0181 30 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21226004 Common - hypothetical protein SCO7747 55 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221882 Common - transmembrane protein SCO3457 25 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 21223633 Nonpathogen - membrane protei SCO5266 1 None None None 21223089 Common rplP 50S ribosomal protein L16 SCO4709 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 21222982 Common - NADH dehydrogenase subunit NuoA2 SCO4599 161 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 21221942 Common - integral membrane protein SCO3521 12 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 21224873 Common - glycosyl hydrolase (secreted protein) SCO6572 125 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 21220819 Common - integral membrane protein SCO2351 7 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21221297 Common - oxidoreductase SCO2847 130 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21224325 Nonpathogen - hypothetical protein SCO5988 1 None None None 32141236 Common - serine/threonine protein kinase (fragment) SCO4423 184 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21219324 Common - hypothetical protein SCO0802 9 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 21222721 Common - integral membrane protein SCO4329 9 None None None 32141116 Common - hypothetical protein SCO0577 14 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21221474 Common - hypothetical protein SCO3031 10 None None None 21225154 Nonpathogen - hypothetical protein SCO6863 1 None None None 21225751 Common - hypothetical protein SCO7483 26 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21222306 Common - hypothetical protein SCO3899 55 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 21224062 Common - peptide transport permease SCO5714 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21219024 Common - monooxygenase SCO0486 77 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21223888 Common - hypothetical protein SCO5533 119 COG2353 COG2353, Uncharacterized conserved protein Function unknown 21220212 Common - regulator SCO1718 16 COG1309 AcrR, Transcriptional regulator Transcription 21221165 Common - polysaccharide deacetylase SCO2710 16 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21222922 Nonpathogen - hypothetical protein 2SCD409c SCO4538 1 None None None 21221265 Common - TetR-family transcriptional regulator SCO2815 11 COG1309 AcrR, Transcriptional regulator Transcription 21222219 Common - transmembrane transport protein SCO3809 107 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21218692 Common - probable transcriptional regulator SCO0132 30 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 21220479 Common - hypothetical protein SCO1997 20 None None None 21219104 Common rpmG 50S ribosomal protein L33 SCO0570 108 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 21220405 Common - integral membrane protein SCO1918 102 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 21221691 Nonpathogen - regulatory protein SCO3258 2 None None None 21224034 Common - sugar hydrolase SCO5685 94 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21220368 Common - secreted pectate lyase SCO1880 21 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 21221955 Nonpathogen - large ATP-binding protein SCO3534 3 None None None 21222013 Common - hypothetical protein SCO3597 48 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 21220157 Common - glycerol-3-phosphate dehydrogenase SCO1661 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 32141122 Common - ABC transporter SCO0742 244 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21221582 Common - two-component system response regulator SCO3144 132 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225745 Nonpathogen - hypothetical protein SCO7477 4 None None None 21224915 Nonpathogen - hypothetical protein SCO6617 1 None None None 21222631 Common - tRNA/rRNA methyltransferase SCO4236 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 21224814 Common - hypothetical protein SCO6511 43 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 21223801 Common - trehalose synthase SCO5442 173 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21223579 Common - hypothetical protein SCO5211 162 COG1162 COG1162, Predicted GTPases General function prediction only 21220959 Common - hypothetical protein SCO2497 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 21219413 Common - hypothetical protein SCO0893 23 COG2327 WcaK, Uncharacterized conserved protein Function unknown 21222027 Common - hypothetical protein SCO3611 39 COG3346 COG3346, Uncharacterized conserved protein Function unknown 21221484 Common - hypothetical protein SCO3041 13 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 21219648 Common - oxidoreductase, iron-sulphur binding subunit SCO1134 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 21222194 Nonpathogen - lipoprotein SCO3783 1 None None None 21220790 Nonpathogen - secreted protein SCO2322 2 None None None 21221576 Common - galactose-1-phosphate uridylyltransferase SCO3138 79 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 21219595 Common - hypothetical protein SCO1080 11 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 21220073 Common - thiamine biosynthesis lipoprotein precursor SCO1575 81 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 21222158 Common - hypothetical protein SCO3746 53 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 21224572 Common - reductase SCO6251 85 COG0431 COG0431, Predicted flavoprotein General function prediction only 32141132 Common - ABC transporter transmembrane subunit SCO1147 236 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21224521 Common - secreted protein SCO6197 3 None None None 21224740 Common - hypothetical protein SCO6433 37 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 21219901 Common - hypothetical protein SCO1397 21 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 21218890 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase SCO0346 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 21219420 Common - transmembrane efflux protein SCO0900 39 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 21225602 Common - two-component system sensory histidine kinase SCO7327 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21223358 Common - hypothetical protein 2SCK3608 SCO4985 3 None None None 21223696 Common - hypothetical protein SCO5335 6 None None None 21222313 Common rpsF 30S ribosomal protein S6 SCO3906 205 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 21224651 Common - transposase SCO6338 7 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 21222001 Nonpathogen - hypothetical protein SCO3584 1 None None None 21220315 Nonpathogen - membrane protein SCO1826 2 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 21222296 Common - thioredoxin SCO3889 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 21220209 Common - homogentisate 1,2-dioxygenase SCO1715 51 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 21220304 Common - enoyl-(acyl carrier protein) reductase SCO1814 177 COG0623 FabI, Enoyl- acyl-carrier-protein 21221548 Common - transcriptional-repair coupling factor SCO3109 214 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 21224190 Common - secreted protein SCO5846 35 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 21225794 Common - hypothetical protein SCO7529 15 None None None 21220085 Common - integral membrane protein SCO1588 38 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21220277 Common - iron-siderophore uptake system ATP-binding component SCO1785 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 21220595 Common - anthranilate synthase SCO2117 155 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 21219268 Nonpathogen - hypothetical protein SCO0744 3 None None None 21224472 Nonpathogen - hypothetical protein SCO6146 2 None None None 21223750 Common - alkanal monooxygenase (luciferase) SCO5390 6 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21224939 Nonpathogen - hypothetical protein SCO6642 1 None None None 21224829 Nonpathogen - hypothetical protein SCO6527 6 COG1950 COG1950, Predicted membrane protein Function unknown 21224963 Common - two-component regulator SCO6667 195 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221057 Common - hypothetical protein SCO2599 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 21218917 Common - secreted protein SCO0373 3 None None None 21220660 Common - hypothetical protein SCO2186 8 None None None 21220967 Common - metal transport ABC transporter SCO2506 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 21223928 Common rnc ribonuclease III SCO5572 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 21219937 Common - CbxX/CfqX family protein SCO1434 52 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 21222786 Common - integral membrane transport protein SCO4396 5 None None None 21223181 Common - hypothetical protein SCO4803 40 COG0714 COG0714, MoxR-like ATPases General function prediction only 21223649 Common - two-component system response regulator SCO5283 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21221072 Common - folylpolyglutamate synthase SCO2614 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 21218714 Nonpathogen - hypothetical protein SCO0157 1 None None None 21221929 Common - maturase-related protein SCO3508 56 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 21222322 Common - transmembrane efflux protein SCO3915 167 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224739 Common - peptide synthase SCO6432 163 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21219191 Common - binding protein dependent transport protein SCO0661 139 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21220176 Common - gluconate dehydrogenase SCO1681 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21223303 Nonpathogen - hypothetical protein SCO4929 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21223717 Common - homoserine kinase SCO5356 83 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 21224455 Common - hypothetical protein SCO6128 5 None None None 21219273 Common - dehydratase SCO0749 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 21225981 Common - hypothetical protein SCO7722 12 None None None 21224236 Common - thioesterase SCO5894 49 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21223853 Common - hypothetical protein SCO5497 16 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 21223839 Common - hypothetical protein SCO5482 9 None None None 21225945 Common - hypothetical protein SCO7685 16 COG4693 PchG, Oxidoreductase (NAD-binding), involved in siderophore biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21222235 Common - ABC-transporter transmembrane component SCO3825 57 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21223548 Common - peptidase SCO5179 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21219770 Common - gntR-family transcriptional regulator SCO1262 9 COG2188 PhnF, Transcriptional regulators Transcription 32141195 Common - aminotransferase SCO3227 142 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 21223640 Common - hypothetical protein SCO5273 33 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 21223353 Nonpathogen - hypothetical protein 2SCK3603c SCO4980 1 None None None 21224436 Common - integral membrane protein SCO6107 71 COG1295 Rbn, Predicted membrane protein Function unknown 21220083 Common - hypothetical protein SCO1586 34 COG3393 COG3393, Predicted acetyltransferase General function prediction only 21220699 Common - acetyltransferase SCO2227 10 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21220846 Common - acetyltransferase SCO2379 7 COG0456 RimI, Acetyltransferases General function prediction only 21220066 Common - tetR-family transcriptional regulator SCO1568 18 None None None 21222641 Common - hypothetical protein SCO4246 50 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 21220553 Common - ribosomal large subunit pseudouridine synthase SCO2073 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 21219819 Common - transcriptional regulatory protein SCO1312 107 COG1396 HipB, Predicted transcriptional regulators Transcription 32141300 Common - aminotransferase SCO6412 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 21225491 Common - integral membrane protein SCO7214 11 COG1511 COG1511, Predicted membrane protein Function unknown 21220020 Common ruvC Holliday junction resolvase SCO1520 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 21224227 Nonpathogen - hypothetical protein SCO5885 2 None None None 21219013 Common - solute-binding lipoprotein SCO0473 145 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 21222008 Common - hypothetical protein SCO3592 10 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 21221233 Common - pyridoxal-dependent decarboxylase SCO2782 119 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 21220691 Common - hypothetical protein SCO2219 5 None None None 21220936 Common - nitrate reductase SCO2473 186 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 21225931 Common - transferase SCO7671 39 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 21223122 Common - hypothetical protein SCO4743 14 COG1396 HipB, Predicted transcriptional regulators Transcription 21224703 Common - IS110 transposase/integrase SCO6391 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 21222151 Common - epimerase SCO3739 138 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21224543 Nonpathogen - lipoprotein SCO6221 1 None None None 21224001 Nonpathogen - hypothetical protein SCO5650 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 21224022 Nonpathogen - hypothetical protein SCO5672 1 None None None 21222371 Common - hypothetical protein SCO3967 33 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 21219134 Common - secreted protein SCO0601 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 21219150 Common - hypothetical protein SCO0618 80 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21219447 Common - hypothetical protein SCO0928 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 21222793 Common - ABC transport system integral membrane protein SCO4404 30 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21224589 Common - histidine kinase SCO6268 85 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21225692 Common - sensor histidine-kinase SCO7422 9 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21226017 Common - hypothetical protein SCO7763 6 COG1787 COG1787, Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes Defense mechanisms 21223002 Nonpathogen - integral membrane protein SCO4619 1 None None None 21220340 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase SCO1851 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 21221862 Common - fatty acid CoA ligase SCO3436 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21224251 Common - probable secreted protease SCO5912 30 COG3291 COG3291, FOG: PKD repeat General function prediction only 21220447 Common - ionic transporter SCO1962 42 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 21224985 Common - transmembrane transport protein SCO6690 117 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224730 Common - lipoate-protein ligase SCO6423 75 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 21220879 Nonpathogen - hypothetical protein SCO2412 2 None None None 21222989 Common - NADH dehydrogenase subunit NuoL2 SCO4606 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 21219159 Common - ATP utilising protein SCO0627 88 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21226032 Common - oxidoreductase SCO7779 149 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21225533 Common - protease (secreted protein) SCO7256 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21219029 Common - ABC transporter transmembrane protein SCO0491 224 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21222662 Nonpathogen - hypothetical protein SCO4269 1 None None None 21225955 Common - hypothetical protein SCO7695 5 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21223432 Nonpathogen - integral membrane protein SCO5060 1 None None None 21219406 Common - LacI-family transcriptional regulator SCO0886 123 COG1609 PurR, Transcriptional regulators Transcription 21219002 Common - oxidoreductase SCO0462 111 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 21219622 Nonpathogen - hypothetical protein 2SCG423c SCO1107 1 None None None 21224567 Common - transcriptional regulator for glyoxylate bypass SCO6246 123 COG1414 IclR, Transcriptional regulator Transcription 21219033 Common - iron-siderophore ABC-transporter ATP-binding protein SCO0495 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 21222092 Common - hypothetical protein SCO3679 81 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225011 Common - acyl-[acyl-carrier protein] desaturase SCO6717 11 None None None 21219967 Common - secreted protein SCO1465 22 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219924 Common - hypothetical protein SCO1421 18 None None None 21219959 Common - transport protein SCO1457 10 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224626 Common - hydrolase SCO6308 172 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 21224282 Common - hypothetical protein SCO5944 7 None None None 21219905 Common - hypothetical protein SCO1401 10 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21226042 Common - secreted oxidoreductase SCO7791 54 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21223794 Common - two-component sensor kinase SCO5435 94 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 21221786 Nonpathogen - hypothetical protein SCO3357 2 None None None 21222673 Common - reductase SCO4280 30 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 21224164 Common - RNA polymerase sigma factor RpoD SCO5820 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 21225526 Nonpathogen - hypothetical protein SCO7249 1 None None None 21219232 Common - lipoprotein SCO0706 74 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 21219532 Nonpathogen - hypothetical protein 2SCG229c SCO1015 1 None None None 21221317 Common - hypothetical protein SCO2868 4 None None None 21225643 Common - transmembrane transport protein SCO7369 127 None None None 21222436 Nonpathogen - hypothetical protein SCO4033 1 None None None 21221556 Nonpathogen - hypothetical protein SCO3117 2 None None None 21223197 Common - serine/threonine protein kinase SCO4820 114 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21224929 Nonpathogen - hypothetical protein SCO6632 1 None None None 21223187 Common - succinyl-CoA synthetase subunit alpha SCO4809 216 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 21219206 Common - integral membrane sensor protein SCO0676 72 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 21223665 Common - integral membrane cell-cycle protein SCO5302 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 21222689 Common groEL chaperonin GroEL SCO4296 243 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 21224368 Common - hypothetical protein SCO6036 9 COG3153 COG3153, Predicted acetyltransferase General function prediction only 32141222 Common - hypothetical protein SCO3964 41 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 21225191 Nonpathogen - hypothetical protein SCO6901 1 None None None 21222904 Nonpathogen - integral membrane protein SCO4519 1 None None None 21224011 Common - secreted peptidase SCO5660 110 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21218985 Common - hypothetical protein SCO0443 113 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 21219812 Nonpathogen - hypothetical protein SCO1305 11 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 21223273 Common - hypothetical protein SCO4899 8 None None None 21218776 Nonpathogen - hypothetical protein SCO0223 1 None None None 32141280 Common - UDP-N-acetylglucosamine transferase SCO5998 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 21218893 Common - oxidoreductase (secreted protein) SCO0349 113 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21222346 Common - serine/threonineprotein kinase SCO3941 44 None None None 21220925 Common - secreted protein SCO2461 10 None None None 21225219 Nonpathogen - hypothetical protein SCO6932 2 None None None 21225914 Common - hypothetical fusion protein SCO7653 14 None None None 21225701 Nonpathogen - integral membrane protein SCO7431 1 None None None 21222939 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase SCO4556 222 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221537 Common - secreted protein SCO3098 12 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 21224977 Common - serine/threonine protein kinase SCO6681 8 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21219556 Common - DNA repair protein SCO1040 56 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 21219149 Common - hypothetical protein SCO0616 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 21220439 Nonpathogen - hypothetical protein SCO1954 2 None None None 21220528 Common - DNA-binding protein SCO2047 9 COG0640 ArsR, Predicted transcriptional regulators Transcription 21220856 Common acpP acyl carrier protein SCO2389 204 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222932 Nonpathogen - type IV peptidase SCO4549 5 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21222543 Common - polyphosphate kinase SCO4145 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 21223276 Nonpathogen - secreted protein SCO4902 1 None None None 21220940 Common - short chain dehydrogenase SCO2477 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21225827 Common - ABC transporter solute binding lipoprotein SCO7563 181 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21222568 Nonpathogen - secreted protein SCO4171 1 None None None 21220580 Common - transcriptional regulator SCO2100 110 COG1309 AcrR, Transcriptional regulator Transcription 21221841 Common - transcriptional regulator SCO3414 37 COG1846 MarR, Transcriptional regulators Transcription 32141211 Common - transcriptional regulator SCO3623 103 COG1802 GntR, Transcriptional regulators Transcription 21221336 Nonpathogen - membrane protein SCO2887 1 None None None 21225192 Nonpathogen - hypothetical protein SCO6902 1 None None None 21223175 Common - ATP-dependent DNA helicase II SCO4797 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 21224130 Common - two-component regulator SCO5785 187 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225982 Nonpathogen - hypothetical protein SCO7723 2 None None None 21221398 Common - hypothetical protein SCO2953 10 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 21222614 Nonpathogen - small hydrophilic protein SCO4218 1 None None None 21221769 Common - ABC transporter ATP-binding subunit SCO3339 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21219549 Nonpathogen - hypothetical protein SCO1033 1 COG3462 COG3462, Predicted membrane protein Function unknown 21223213 Common glyA serine hydroxymethyltransferase SCO4837 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 21225338 Common - methyltransferase SCO7055 64 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21220350 Nonpathogen - integral membrane protein SCO1862 1 None None None 32141337 Nonpathogen - hypothetical protein SCO7589 1 None None None 21224552 Common - sugar transport system permease protein SCO6230 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21225110 Nonpathogen - hypothetical protein SCO6817 1 None None None 21221583 Nonpathogen - secreted protein SCO3145 1 COG1520 COG1520, FOG: WD40-like repeat Function unknown 21219249 Common - transcriptional regulator SCO0724 72 COG1737 RpiR, Transcriptional regulators Transcription 21219436 Common - oxygenase SCO0917 102 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21220016 Common secD preprotein translocase subunit SecD SCO1516 205 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 21219762 Common - hypothetical protein SCO1253 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21223113 Common rplM 50S ribosomal protein L13 SCO4734 229 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 21220806 Common - O-methyltransferase SCO2338 104 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 21218671 Common - aminoglycoside nucleotidyltransferase SCO0107 5 None None None 21220870 Common - hypothetical protein SCO2403 10 None None None 21223602 Common - sugar transporter integral membrane protein SCO5234 184 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21225820 Common - sugar transport permease SCO7556 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21223812 Common - two-component system sensor kinase SCO5454 153 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21218858 Common - tetR-family transcriptional regulator SCO0310 24 COG1309 AcrR, Transcriptional regulator Transcription 21222573 Common - hypothetical protein SCO4176 6 None None None 21225699 Nonpathogen - hypothetical protein SCO7429 1 None None None 21218725 Common - regulator protein SCO0168 13 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 21221079 Common - integral membrane protein SCO2622 11 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 21225343 Common - hypothetical protein SCO7060 97 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 21224374 Common - secreted protease SCO6043 37 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221406 Nonpathogen - integral membrane protein SCO2961 2 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 21218911 Nonpathogen - hypothetical protein SCO0367 1 COG3619 COG3619, Predicted membrane protein Function unknown 21224665 Nonpathogen - hypothetical protein SCO6352 3 None None None 21224044 Common - metalloprotease SCO5695 207 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 21226044 Nonpathogen - hypothetical protein SCO7792 1 None None None 21220409 Common - dioxygenase ferredoxin subunit SCO1923 85 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 21224224 Nonpathogen - RedV protein SCO5882 2 None None None 21218910 Common - hypothetical protein SCO0366 19 None None None 21223103 Common - methionine aminopeptidase SCO4724 244 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 21220587 Common thiG thiazole synthase SCO2109 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 21221121 Nonpathogen - hypothetical protein SCO2665 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 21221149 Nonpathogen - hypothetical protein SCO2694 1 None None None 21223726 Nonpathogen - ATP synthase protein I SCO5366 1 None None None 21219997 Common - chorismate synthase SCO1496 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 21220237 Nonpathogen - ABC-transporter transmembrane protein SCO1743 1 None None None 21219397 Nonpathogen - hypothetical protein SCO0876 1 None None None 21222597 Common - hypothetical protein SCO4201 64 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225376 Common - flavohemoprotein SCO7094 112 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 21220979 Common - two-component sensor kinase SCO2518 23 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220634 Common - aminotransferase SCO2157 211 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 21224144 Common - aminotransferase SCO5799 234 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 21225023 Common - hypothetical protein SCO6729 45 COG3268 COG3268, Uncharacterized conserved protein Function unknown 21225549 Common - isomerase SCO7272 13 None None None 21223827 Common - serine hydroxymethyltransferase SCO5470 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 21218797 Common - secreted protein SCO0244 11 COG2367 PenP, Beta-lactamase class A Defense mechanisms 21222333 Common - hypothetical protein SCO3927 26 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 21220626 Common - Rieske iron-sulfur protein SCO2149 33 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 21223455 Common - hypothetical protein SCO5084 41 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21221120 Common - sugar-binding protein SCO2664 161 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 21224203 Common hemH ferrochelatase SCO5859 85 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 21221815 Common - transcriptional regulator SCO3387 45 COG0640 ArsR, Predicted transcriptional regulators Transcription 21221848 Common - hypothetical protein SCO3421 6 None None None 21222889 Common - methyltransferase SCO4504 52 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21220667 Common - lipoyl synthase SCO2194 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 21218881 Common - integral membrane protein SCO0336 20 COG3268 COG3268, Uncharacterized conserved protein Function unknown 21222646 Nonpathogen - secreted protein SCO4251 10 None None None 21219410 Common - short chain oxidoreductase SCO0890 119 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21219777 Common - pyruvate dehydrogenase beta subunit SCO1269 152 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 21220396 Common - hypothetical protein SCO1909 3 COG4043 COG4043, Uncharacterized conserved protein Function unknown 21220045 Common - aminotransferase SCO1546 198 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 21221253 Nonpathogen - secreted protein SCO2802 3 None None None 21222026 Common - peptide hydrolase SCO3610 136 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21226085 Common - hypothetical protein SCO7836 3 None None None 21218971 Common - oxidoreductase SCO0429 144 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21219171 Common - hypothetical protein SCO0640 16 COG3682 COG3682, Predicted transcriptional regulator Transcription 21225227 Common - ATP/GTP binding protein SCO6940 28 COG2229 COG2229, Predicted GTPase General function prediction only 21224500 Common - hypothetical protein SCO6175 5 COG2267 PldB, Lysophospholipase Lipid metabolism 21219676 Common - hypothetical protein SCO1163 12 COG5661 COG5661, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 32141151 Common - excinuclease ABC subunit B SCO1966 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 21223943 Nonpathogen - lipoprotein SCO5588 1 None None None 21219099 Common - polyprenyl synthetase SCO0565 224 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 21220064 Common - acyltransferase SCO1566 107 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21224673 Common - ABC transporter ATP-binding protein SCO6360 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21223537 Nonpathogen - integral membrane protein SCO5168 1 None None None 21224813 Common - hypothetical protein SCO6510 189 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221762 Common - transmembrane transport protein SCO3331 15 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225139 Nonpathogen - hypothetical protein SCO6847 1 None None None 21225307 Nonpathogen - hypothetical protein SCO7022 1 None None None 21225891 Common - isomerase SCO7630 92 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21224944 Nonpathogen - integral membrane protein SCO6647 15 COG5050 EPT1, sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases Lipid metabolism 21225408 Common - hypothetical protein SCO7126 10 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21218827 Common - hypothetical protein SCO0277 10 COG3340 PepE, Peptidase E Amino acid transport and metabolism 21223674 Nonpathogen - secreted protein SCO5311 4 COG3652 COG3652, Predicted outer membrane protein Function unknown 21221049 Nonpathogen - secreted protein SCO2591 5 None None None 21220777 Common - two-component system response regulator SCO2308 200 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21224653 Common - hypothetical protein SCO6340 20 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 21224174 Common - hypothetical protein SCO5830 19 COG4759 COG4759, Uncharacterized protein conserved in bacteria containing thioredoxin-like domain Posttranslational modification, protein turnover, chaperones 21225092 Common tdh L-threonine 3-dehydrogenase SCO6799 207 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21221380 Common - permease binding-protein component SCO2933 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 21222258 Common - integral membrane protein SCO3849 17 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 32141287 Common - peptide-binding transport protein SCO6114 114 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21222618 Common - hypothetical protein SCO4222 14 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21219184 Common - hypothetical protein SCO0654 21 COG5637 COG5637, Predicted integral membrane protein Function unknown 21221112 Common - hypothetical protein SCO2655 93 COG1403 McrA, Restriction endonuclease Defense mechanisms 21225189 Nonpathogen - hypothetical protein SCO6899 1 None None None 21225206 Common - hypothetical protein SCO6918 5 None None None 21224464 Common - transmembrane protein SCO6138 36 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 21224726 Nonpathogen - hypothetical protein SCO6419 1 None None None 21219944 Common - integral membrane protein SCO1442 39 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 21219544 Common - lyase SCO1028 208 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 21223683 Nonpathogen - whiE protein I SCO5320 3 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 21221635 Common - deoR-family transcriptional regulator SCO3200 83 COG2378 COG2378, Predicted transcriptional regulator Transcription 32141111 Common - hydrolase SCO0461 139 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21223964 Nonpathogen - hypothetical protein SCO5609 1 None None None 21221854 Common rpmE2 50S ribosomal protein L31 type B SCO3427 143 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 21223155 Common - serine/threonine protein kinase SCO4776 20 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21219656 Common - oxidoreductase SCO1142 93 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21220454 Common - dioxygenase SCO1970 18 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21222105 Common - anti-sigma factor antagonist SCO3692 8 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21221271 Common - secreted pectate lyase SCO2821 21 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 21223026 Common - adenosine deaminase SCO4644 102 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 21223138 Common - secreted protein SCO4759 58 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21225648 Common - acetyltransferase SCO7375 12 COG0456 RimI, Acetyltransferases General function prediction only 21222817 Common fbiC FO synthase SCO4429 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 21225812 Common - hypothetical protein SCO7548 108 COG1262 COG1262, Uncharacterized conserved protein Function unknown 21218820 Common - hypothetical protein SCO0269 8 None None None 21220342 Common - precorrin-2 C20-methyltransferase SCO1853 114 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 21225436 Common - hypothetical protein SCO7156 8 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21225877 Common - DNA-binding protein SCO7615 6 None None None 21222146 Common - hypothetical protein SCO3734 8 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 21224559 Common - hypothetical protein SCO6238 10 None None None 21219458 Common - hydrolase SCO0939 109 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221526 Nonpathogen - hypothetical protein SCO3085 1 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 21218785 Nonpathogen - hypothetical protein SCO0232 1 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 21220378 Common - hypothetical protein SCO1891 8 None None None 21220417 Common - hypothetical protein SCO1931 4 None None None 21221064 Common - hypothetical protein SCO2606 64 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 21224950 Common - hypothetical protein SCO6654 88 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 21220830 Common - hypothetical protein SCO2362 24 None None None 21220472 Common - hypothetical protein SCO1990 91 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 21221508 Common - anti anti sigma factor SCO3067 53 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21221950 Nonpathogen - hypothetical protein SCO3529 1 None None None 21219358 Nonpathogen - hypothetical protein SCO0837 1 None None None 21222682 Nonpathogen - secreted protein SCO4289 1 None None None 32141299 Nonpathogen - integral membrane protein SCO6365 4 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 21219168 Common - hypothetical protein SCO0637 27 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 21225882 Common - hypothetical protein SCO7620 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 21224456 Common - DNA-binding protein SCO6129 6 None None None 21224604 Nonpathogen - hypothetical protein SCO6285 1 None None None 21220677 Common - hypothetical protein SCO2204 11 None None None 21222623 Nonpathogen - hypothetical protein SCO4227 1 None None None 21221792 Common - acetyltransferase SCO3363 19 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 21222492 Common - hypothetical protein SCO4090 7 None None None 21219831 Common - hypothetical protein SCO1325 111 COG1733 COG1733, Predicted transcriptional regulators Transcription 21224631 Common - integral membrane protein SCO6313 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 21221150 Common - hypothetical protein SCO2695 95 COG1262 COG1262, Uncharacterized conserved protein Function unknown 21221133 Common - putative ABC transporter ATP-binding protein SCO2677 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21225797 Nonpathogen - secreted protein SCO7532 1 None None None 21222463 Nonpathogen - hypothetical protein 2SCD6026 SCO4060 1 None None None 21224782 Common - hypothetical protein SCO6478 182 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21222111 Common - heavy metal resistance membrane protein SCO3698 133 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 21223034 Common rplJ 50S ribosomal protein L10 SCO4652 206 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 21222680 Common - hypothetical protein SCO4287 2 None None None 21223308 Common - lipoprotein SCO4934 23 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 21225221 Nonpathogen - secreted protein SCO6934 1 None None None 21221492 Nonpathogen - hypothetical protein SCO3050 2 None None None 21221188 Nonpathogen - integral membrane protein SCO2735 1 None None None 21222865 Common - transferase SCO4478 5 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 21222507 Common - bifunctional enzyme deaminase/reductase SCO4106 160 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 21219582 Common - integral membrane transport protein SCO1067 58 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 21225688 Common - cytochrome P450-family protein SCO7418 63 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21225903 Common - hypothetical protein SCO7642 7 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21218743 Common - phytoene dehydrogenase (phytoene desaturase) (secreted protein) SCO0186 69 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 32141164 Common - hypothetical protein SCO2255 8 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 21219798 Common - hypothetical protein SCO1291 13 None None None 21225284 Common - cytochrome P450 SCO6998 65 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21222653 Nonpathogen - hydrolytic protein SCO4258 4 None None None 21220420 Common - cytochrome oxidase assembly factor SCO1934 177 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 21221411 Common smpB SsrA-binding protein SCO2966 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 21225246 Common - putative monovalent cation/H+ antiporter subunit G SCO6959 64 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 21222249 Nonpathogen - hypothetical protein SCO3840 1 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 21219837 Common - multi-domain regulatory protein SCO1331 103 COG3903 COG3903, Predicted ATPase General function prediction only 21224159 Common - ATP-dependent DNA helicase SCO5815 209 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 21224200 Nonpathogen - hypothetical protein SCO5856 1 None None None 21222477 Common - ABC transport protein, ATP-binding subunit SCO4075 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21224602 Common - hypothetical protein SCO6283 86 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223820 Nonpathogen - hypothetical protein SCO5462 2 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 21224309 Common - hypothetical protein SCO5972 14 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 21221105 Nonpathogen - hypothetical protein SCO2648 1 None None None 21224394 Common - ABC transporter permease protein SCO6064 103 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 21225049 Common - glycosyltransferase SCO6756 14 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 21220031 Common thrS threonyl-tRNA synthetase SCO1531 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21221986 Common - hypothetical protein SCO3568 65 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21220820 Common - hypothetical protein SCO2352 14 COG5552 COG5552, Uncharacterized conserved protein Function unknown 21220464 Nonpathogen - hypothetical protein SCO1981 1 None None None 21219615 Nonpathogen - integral membrane protein SCO1100 1 None None None 21222213 Common - hypothetical protein SCO3803 36 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 21218934 Common - transferase SCO0391 39 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21225619 Common - secreted protein SCO7344 6 None None None 21224547 Common - secreted protein SCO6225 17 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 21225728 Common - ABC transporter ATP-binding protein SCO7459 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 21218874 Common - esterase SCO0329 52 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21225756 Common - integral membrane binding protein dependent transport protein SCO7488 138 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21226057 Nonpathogen - hypothetical protein SCO7807 1 None None None 21220456 Common - sugar kinase SCO1972 41 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21225165 Nonpathogen - hypothetical protein SCO6874 1 None None None 21220504 Common - hypothetical protein SCO2022 11 None None None 21219829 Common - integral membrane protein SCO1323 54 COG0398 COG0398, Uncharacterized conserved protein Function unknown 21219822 Common - siderophore binding protein SCO1315 205 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 21218641 Common - integral membrane permease SCO0066 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21219828 Common - hypothetical protein SCO1322 14 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 21218928 Nonpathogen - hypothetical protein SCO0385 1 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 21222454 Common - hypothetical protein SCO4051 51 COG3542 COG3542, Uncharacterized conserved protein Function unknown 21220852 Common - hypothetical protein SCO2385 143 COG1741 COG1741, Pirin-related protein General function prediction only 21221164 Common - integral membrane protein SCO2709 21 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 21222565 Common - oxidoreductase SCO4168 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21222748 Common - integral membrane protein SCO4357 13 None None None 21222513 Common - hypothetical protein SCO4113 97 COG0579 COG0579, Predicted dehydrogenase General function prediction only 21223097 Common rplF 50S ribosomal protein L6 SCO4717 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 32141183 Common - hypothetical protein SCO2864 5 None None None 21218836 Nonpathogen - secreted peptidoglycan binding protein SCO0286 1 None None None 21222256 Common - secreted penicillin-binding protein SCO3847 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21225382 Common - oxidoreductase SCO7100 40 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21224736 Nonpathogen - hypothetical protein SCO6429 3 COG2308 COG2308, Uncharacterized conserved protein Function unknown 21224584 Common - hypothetical protein SCO6263 39 COG4279 COG4279, Uncharacterized conserved protein Function unknown 21220701 Common - maltose permease SCO2229 177 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 21219311 Nonpathogen - hypothetical protein 3SCF6020c SCO0788 1 None None None 21218904 Common - probable DNA-binding, LacI family, regulator SCO0360 127 COG1609 PurR, Transcriptional regulators Transcription 21223443 Nonpathogen - hydroxylacyl-CoA dehydrogenase SCO5071 2 None None None 21219035 Common - iron-siderophore permease transmembrane protein SCO0497 182 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 21219760 Common - integral membrane protein SCO1251 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21224536 Common - hydroxydechloroatrazine ethylaminohydrolase SCO6213 170 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 21224056 Common rbfA ribosome-binding factor A SCO5708 161 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 21222770 Common - acetyl/propionyl CoA carboxylase, beta subunit SCO4380 150 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 21218925 Common - UDP-glucose/GDP-mannose family dehydrogenase (putative secreted protein) SCO0382 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 21222780 Common - hypothetical protein SCO4390 28 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 21219307 Nonpathogen - secreted protein SCO0784 6 None None None 21219139 Common - hypothetical protein SCO0606 9 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 21225545 Common - adenosine deaminase SCO7268 116 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 21223348 Common - hypothetical protein SCO4975 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 21225072 Nonpathogen - hypothetical protein SCO6779 1 None None None 21218604 Nonpathogen - IS element ATP-binding protein SCO0025 3 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 21222535 Common - hypothetical protein SCO4137 72 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 21220189 Common - penicillin acylase SCO1694 54 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 21223028 Nonpathogen secE preprotein translocase subunit SecE SCO4646 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 21224073 Nonpathogen - hypothetical protein SCO5726 1 None None None 21219517 Common - integrase SCO1000 36 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 21220254 Common - chorismate mutase SCO1762 39 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 21223400 Common - hypothetical protein SCO5027 10 None None None 21219360 Common - transmembrane transport protein SCO0839 40 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21224864 Common - 2-dehydropantoate 2-reductase SCO6562 80 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 21218849 Common - monooxygenase SCO0300 48 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21222913 Common - integral membrane protein SCO4528 9 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 21222101 Common - hypothetical protein SCO3688 20 COG5637 COG5637, Predicted integral membrane protein Function unknown 21222551 Common - hypothetical protein SCO4153 142 COG1733 COG1733, Predicted transcriptional regulators Transcription 21224333 Common - hypothetical protein SCO5996 81 COG2319 COG2319, FOG: WD40 repeat General function prediction only 21222636 Common - proteinase SCO4241 37 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21220247 Nonpathogen - hypothetical protein 2SCI4307c SCO1754 1 None None None 21222800 Nonpathogen - calcium binding protein SCO4411 3 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 21221456 Common - two-component system response regulator SCO3013 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21219887 Common - hypothetical protein SCO1383 18 COG0789 SoxR, Predicted transcriptional regulators Transcription 21220905 Nonpathogen - hypothetical protein SCO2441 1 None None None 21223237 Nonpathogen - hypothetical protein SCO4862 1 None None None 21224433 Nonpathogen - secreted protein SCO6104 2 None None None 21218635 Nonpathogen - hypothetical protein SCO0060 1 None None None 21220896 Common - sugar transporter membrane protein SCO2432 175 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219386 Nonpathogen - integral-membrane protein SCO0865 1 None None None 21219299 Common - integral membrane protein SCO0776 43 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 21221211 Common - probable transposase SCO2759 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 21223970 Nonpathogen - hypothetical protein SCO5615 1 None None None 21226075 Nonpathogen - hypothetical protein SCO7826 5 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 21225475 Common - ion transport integral membrane protein SCO7196 88 None None None 21226060 Common - oxidoreductase SCO7810 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21219085 Common - hypothetical protein SCO0550 84 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 21223909 Common leuD isopropylmalate isomerase small subunit SCO5554 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 21225569 Common - hypothetical protein SCO7293 28 COG2013 COG2013, Uncharacterized conserved protein Function unknown 21222534 Common - hypothetical protein SCO4136 96 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 21219495 Common - aspartate alpha-decarboxylase SCO0978 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 21224253 Common - probable transcriptional regulator SCO5914 149 COG0583 LysR, Transcriptional regulator Transcription 21220769 Common - hypothetical protein SCO2300 46 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 21221613 Nonpathogen - hypothetical protein SCO3176 2 None None None 21222047 Nonpathogen - hypothetical protein SCO3632 6 COG1510 COG1510, Predicted transcriptional regulators Transcription 21225496 Common - phosphoglycerate mutase SCO7219 5 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21222612 Nonpathogen - hypothetical protein SCO4216 1 None None None 21221012 Common - oxidoreductase SCO2553 125 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 21221097 Common - aspartate-semialdehyde dehydrogenase SCO2640 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 21219246 Common - integral membrane protein SCO0720 2 None None None 21225456 Nonpathogen - hypothetical protein SCO7177 1 COG1378 COG1378, Predicted transcriptional regulators Transcription 21219757 Nonpathogen - hypothetical protein SCO1248 3 None None None 21221447 Nonpathogen - hypothetical protein SCO3004 2 None None None 21221428 Nonpathogen - integral membrane protein SCO2984 1 None None None 21222237 Common - molybdenum cofactor biosynthesis protein SCO3827 194 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 21225537 Common - membrane protein SCO7260 6 COG2261 COG2261, Predicted membrane protein Function unknown 21219814 Nonpathogen - hypothetical protein SCO1307 2 None None None 21223473 Common - mutT-like protein SCO5102 13 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21220917 Nonpathogen - hypothetical protein SCO2453 1 None None None 21225212 Nonpathogen - DNA-binding protein SCO6924 1 None None None 21225259 Common - hypothetical protein SCO6972 7 COG1547 COG1547, Uncharacterized conserved protein Function unknown 21225393 Common - hydroperoxide resistance protein SCO7111 76 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 21219263 Nonpathogen - secreted protein SCO0738 1 None None None 21223045 Nonpathogen - integral membrane protein SCO4664 2 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 21225466 Nonpathogen - lipoprotein SCO7187 5 None None None 21221373 Nonpathogen - secreted protein SCO2926 4 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 21220673 Common - hypothetical protein SCO2200 99 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21218613 Nonpathogen - hypothetical protein SCO0034 1 None None None 21226054 Common - insertion element transposase SCO7803 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220637 Nonpathogen - large membrane protein SCO2160 2 None None None 21219463 Common - hypothetical protein SCO0944 5 None None None 21220715 Common - hypothetical protein SCO2245 5 None None None 21221464 Common - integral membrane protein SCO3021 32 COG1714 COG1714, Predicted membrane protein/domain Function unknown 21223459 Common - actinorhodin polyketide beta-ketoacyl synthase beta subunit SCO5088 207 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222133 Nonpathogen - small membrane protein SCO3720 1 None None None 21223567 Common - hypothetical protein SCO5198 16 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21224898 Common - transcriptional regulator SCO6598 128 COG1609 PurR, Transcriptional regulators Transcription 21225057 Common - squalene-hopene cyclase SCO6764 47 COG1657 SqhC, Squalene cyclase Lipid metabolism 21225867 Common - metallopeptidase SCO7605 42 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 21218697 Common - short chain dehydrogenase SCO0138 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21223384 Common - integral membrane protein SCO5011 60 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 21220869 Common - dehydrogenase SCO2402 175 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21222496 Common - hypothetical protein SCO4094 26 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 21220260 Common - pseudouridine synthase SCO1768 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 21223467 Common - LysR-family transcriptional regulatory protein SCO5096 189 COG0583 LysR, Transcriptional regulator Transcription 21225081 Common - acetyl-CoA acetyltransferase SCO6788 182 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21220115 Nonpathogen - regulatory protein SCO1619 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21221895 Common - extracellular agarase precursor SCO3471 4 None None None 21221788 Common - sensory histidine kinase Contains hydrophobic membrane spanning regions SCO3359 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21219737 Common - acyltransferase SCO1228 123 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21220704 Common - maltose operon transcriptional repressor SCO2232 126 COG1609 PurR, Transcriptional regulators Transcription 21223480 Nonpathogen - hypothetical protein SCO5109 2 None None None 21222735 Nonpathogen - hypothetical protein SCO4343 2 None None None 21221338 Common - sugar transport protein SCO2889 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21222970 Common - hypothetical protein SCO4587 10 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 21225635 Common - DNA-binding protein SCO7361 3 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21225074 Common - regulatory protein SCO6781 71 COG1309 AcrR, Transcriptional regulator Transcription 21221489 Common - hypothetical protein SCO3047 62 COG1316 LytR, Transcriptional regulator Transcription 21224441 Common - oligopeptide ABC transporter integral membrane protein SCO6112 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21220547 Nonpathogen - hypothetical protein SCO2066 1 None None None 21218686 Common - multi-domain beta keto-acyl synthase SCO0126 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21221712 Common - integral membrane efflux protein SCO3279 79 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 21224511 Common - bifunctional synthase/transferase SCO6187 132 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 21220534 Common - histidinol-phosphate aminotransferase SCO2053 223 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 21223786 Nonpathogen - hypothetical protein SCO5427 1 None None None 21224492 Nonpathogen - proline rich protein (membrane protein) SCO6167 2 None None None 21223452 Common - hypothetical protein SCO5081 5 None None None 21218842 Common - beta-xylosidase SCO0293 132 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21223088 Common rpsC 30S ribosomal protein S3 SCO4708 246 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 21221415 Nonpathogen - hypothetical protein SCO2970 2 None None None 21219419 Common - hydrolase SCO0899 148 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21219805 Common - hypothetical protein SCO1298 46 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 21225274 Common - oxidoreductase SCO6988 149 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21223054 Common - deoR-family transcriptional regulator SCO4673 68 COG2378 COG2378, Predicted transcriptional regulator Transcription 21223553 Common - ATP-dependent DNA helicase SCO5184 227 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 21225288 Common - probable amino acid/metabolite permease SCO7002 98 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21219055 Common - tetR family transcriptional regulator SCO0520 42 COG1309 AcrR, Transcriptional regulator Transcription 21219665 Common - helicase SCO1152 138 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 21221085 Common - amino acid permease SCO2628 131 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 21221223 Common - membrane transport protein SCO2772 48 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 21219300 Common - hypothetical protein SCO0777 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 21222964 Common - hypothetical protein SCO4581 71 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 21220540 Nonpathogen - hypothetical protein SCO2059 1 None None None 21219957 Common - hydrolase SCO1455 207 COG0388 COG0388, Predicted amidohydrolase General function prediction only 21221218 Common - secreted ribonuclease SCO2766 23 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 21220091 Common pheT phenylalanyl-tRNA synthetase subunit beta SCO1594 240 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 21221022 Common rpsT 30S ribosomal protein S20 SCO2563 48 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 21219637 Common - hypothetical protein 2SCG3816 SCO1123 9 None None None 21224753 Common - NAD(P)H oxidoreductase SCO6447 64 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 21222494 Common - ATP-dependent helicase SCO4092 132 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 21223064 Common - cold shock protein SCO4684 181 COG1278 CspC, Cold shock proteins Transcription 21223679 Nonpathogen - acyl carrier protein SCO5316 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 32141297 Common - hypothetical protein SCO6325 6 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 21223614 Common - deaminase SCO5247 17 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 21223735 Common - secreted protein SCO5375 14 None None None 21224321 Common - acyl-CoA dehydrogenase SCO5984 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21221998 Common - hypothetical protein SCO3581 143 COG1610 COG1610, Uncharacterized conserved protein Function unknown 21219685 Common - aldehyde dehydrogenase SCO1174 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31340546 Common - prephenate dehydrogenase SCO1761 151 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 21225606 Common - hypothetical protein SCO7331 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 32141254 Common - peptide transport system ATP-binding subunit SCO5116 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 21223703 Nonpathogen - SpdB2 protein SCO5342 1 None None None 21225303 Nonpathogen - hypothetical protein SCO7018 2 COG0439 AccC, Biotin carboxylase Lipid metabolism 21222407 Nonpathogen - small membrane protein SCO4004 1 None None None 21219927 Common - hypothetical protein SCO1424 91 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 21219178 Common - methyltransferase SCO0648 76 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21223437 Common - transcriptional regulator SCO5065 19 COG3899 COG3899, Predicted ATPase General function prediction only 21225042 Common - enoyl coA hydratase SCO6748 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21221835 Common - hypothetical protein SCO3408 80 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 21219899 Common - mutT-like protein SCO1395 19 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21221860 Common - hypothetical protein SCO3433 49 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 21223521 Common - ATP-binding protein SCO5152 233 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 21219140 Nonpathogen - hypothetical lipoportein SCF5531 SCO0607 1 None None None 21220014 Common - adenine phosphoribosyltransferase SCO1514 183 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 21222361 Common - ABC transporter ATP-binding protein SCO3956 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21222086 Common - iron-sulphur-binding reductase SCO3673 102 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 21218805 Common - oxidoreductase SCO0252 84 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21219742 Common - urease accessroy protein SCO1233 6 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 21220614 Common - hypothetical protein SCO2137 7 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 21223335 Common - amino acid deaminase SCO4962 214 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 21223526 Common - metal-transport protein SCO5157 160 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 21223626 Common - permease SCO5259 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 21220898 Common - sugar transporter sugar binding protein SCO2434 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21220793 Common - integral membrane protein SCO2325 12 None None None 21226092 Nonpathogen - hypothetical protein SCO0004 5 None None None 21225326 Common - hypothetical protein SCO7043 7 None None None 21219750 Nonpathogen - hypothetical protein SCO1241 4 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 21225293 Nonpathogen - integral membrane protein SCO7007 2 COG0392 COG0392, Predicted integral membrane protein Function unknown 32141279 Common - oxidase SCO5966 203 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21223861 Nonpathogen - hypothetical protein SCO5505 1 None None None 21220142 Nonpathogen - hypothetical protein SCO1646 3 None None None 21223055 Common - hypothetical protein SCO4674 16 None None None 21220824 Common - hypothetical protein SCO2356 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 21222352 Common - ABC transporter SCO3947 248 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 21220743 Common - ABC transport protein, ATP-binding component SCO2274 237 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 21224340 Common - lipoprotein SCO6005 16 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219258 Nonpathogen - hypothetical protein SCO0733 1 None None None 21221110 Common - hypothetical protein SCO2653 37 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221703 Nonpathogen - hypothetical protein SCO3270 1 None None None 21222473 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase SCO4071 176 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 21225570 Common - hypothetical protein SCO7294 55 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 21218623 Common - oxidoreductase SCO0044 86 COG0778 NfnB, Nitroreductase Energy production and conversion 21221343 Common - integral membrane protein SCO2896 25 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 21219780 Nonpathogen - acyl carrier protein SCO1272 2 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21221086 Nonpathogen - hypothetical protein SCO2629 1 None None None 21222977 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta SCO4594 133 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 21221577 Common - sodium:solute symporter SCO3139 162 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 21219426 Common - hypothetical protein SCO0906 12 None None None 21220196 Common - acyl-CoA dehydrogenase SCO1701 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21221960 Common - DNA polymerase III subunit delta' SCO3541 215 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 32141272 Common - polynucleotide phosphorylase/polyadenylase SCO5737 236 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 21223796 Common - MerR-family transcriptional regulator SCO5437 54 COG0789 SoxR, Predicted transcriptional regulators Transcription 21218935 Common - methyltransferase SCO0392 46 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 21220485 Common - DNA polymerase I SCO2003 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 21222924 Nonpathogen - hypothetical protein 2SCD411c SCO4540 2 None None None 21224767 Common - ADA-like regulatory protein SCO6461 101 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 21225855 Common - hypothetical protein SCO7592 48 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21224181 Common - zinc protease SCO5837 192 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 21222186 Nonpathogen - hypothetical protein SCO3775 3 None None None 21226077 Nonpathogen - Putative DNA-binding protein SCO7828 1 None None None 21220578 Common - methyltransferase SCO2098 22 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 21221595 Nonpathogen - hypothetical protein SCO3158 6 None None None 21218879 Nonpathogen - secreted protein SCO0334 1 None None None 21219370 Nonpathogen - membrane protein SCO0849 1 None None None 21219946 Common - chitinase precursor SCO1444 39 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 32141340 Common - zinc-binding oxidoreductase (fragment) SCO7666 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21222842 Common - transcriptional regulator SCO4454 79 COG1309 AcrR, Transcriptional regulator Transcription 21220415 Common - integral membrane transport protein SCO1929 32 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21221001 Common - glucarate dehydratase SCO2542 114 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21224747 Common - aldehyde dehydrogenase SCO6441 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21219698 Common - secreted cellulase B precursor SCO1187 20 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 21223489 Common - peptide transport system integral membrane protein SCO5119 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21224981 Nonpathogen - hypothetical protein SCO6686 2 None None None 21225753 Nonpathogen - oxidoreductase SCO7485 4 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21224030 Common - glycosyl transferase SCO5681 141 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21219564 Nonpathogen - secreted protein SCO1048 4 None None None 21221139 Common - ATP-binding membrane protein SCO2684 9 COG1159 Era, GTPase General function prediction only 21219912 Nonpathogen - membrane protein SCO1409 4 None None None 21224683 Common - integral membrane protein SCO6371 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 21225875 Nonpathogen - integral membrane protein SCO7613 2 None None None 21220221 Common - hypothetical protein SCO1727 110 COG1801 COG1801, Uncharacterized conserved protein Function unknown 32141306 Common - ROK family protein SCO6566 140 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21219983 Common - dihydroorotate dehydrogenase 2 SCO1482 229 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 21221922 Common - hypothetical protein SCO3501 5 None None None 21224818 Common - protease SCO6515 136 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 21220653 Common - aminopeptidase SCO2179 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 21219062 Common - cold shock protein SCO0527 180 COG1278 CspC, Cold shock proteins Transcription 32141321 Common - succinate-semialdehyde dehydrogenase SCO7035 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21219743 Common ureC urease subunit alpha SCO1234 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 21221517 Nonpathogen - integral membrane protein SCO3076 1 None None None 21225735 Common - ATP/GTP-binding protein SCO7466 32 COG2229 COG2229, Predicted GTPase General function prediction only 21223911 Common - histone-like DNA binding protein SCO5556 110 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 21222262 Common - hypothetical protein SCO3853 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 21219165 Common - hypothetical protein SCO0633 11 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 21224122 Common - glutamate binding protein SCO5776 158 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 32141312 Common - phospholipase C SCO6691 35 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 21218745 Common - methylesterase SCO0188 32 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 21225924 Common - hypothetical protein SCO7663 8 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 21222651 Common - hydrolytic protein SCO4256 7 None None None 21223884 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase SCO5529 207 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 21221027 Common - DNA-binding protein SCO2568 75 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 21224480 Nonpathogen - hypothetical protein SCO6154 1 None None None 32141234 Nonpathogen - hypothetical protein SCO4369 2 None None None 21218652 Common - transposase SCO0083 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21222586 Common - GntR-family transcriptional regulator SCO4190 77 COG2188 PhnF, Transcriptional regulators Transcription 21218774 Common - hypothetical protein SCO0220 11 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 21220750 Common - two-component system response-regulator SCO2281 124 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220837 Common - thiol-specific antioxidant protein SCO2369 230 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 21221176 Nonpathogen - integral membrane protein SCO2722 5 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 21225579 Common - TetR-family regulator SCO7303 17 COG1309 AcrR, Transcriptional regulator Transcription 21223712 Common - regulatory protein SCO5351 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21224381 Common - lipoprotein SCO6050 79 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21224923 Nonpathogen - hypothetical protein SCO6625 1 None None None 21222260 Common - para-aminobenzoate synthase component II SCO3851 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 21219654 Common - integral membrane protein SCO1140 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 21219353 Nonpathogen - hypothetical protein SCO0832 2 None None None 21222879 Common - asnC-family transcriptional regulator SCO4493 155 COG1522 Lrp, Transcriptional regulators Transcription 21225773 Common - hydrolase SCO7506 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21219606 Common - acetyltransferase SCO1091 15 COG0456 RimI, Acetyltransferases General function prediction only 21221442 Common - transferase SCO2998 174 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21221156 Nonpathogen - tyrosinase co-factor SCO2701 1 None None None 21225416 Common - transcriptional regulatory protein SCO7134 44 COG3899 COG3899, Predicted ATPase General function prediction only 21220555 Common - DNA-binding protein SCO2075 133 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 21223036 Common rpoB DNA-directed RNA polymerase subunit beta SCO4654 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 21222178 Common - hypothetical protein SCO3767 13 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 21225810 Common - ABC transporter ATP-binding protein SCO7545 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 21223993 Nonpathogen - hypothetical protein SCO5642 1 None None None 21224880 Common - hypothetical protein SCO6579 17 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 21219282 Nonpathogen - hypothetical protein SCO0758 1 None None None 21219289 Common - secreted endoglucanase SCO0765 20 None None None 21224235 Common - oxidoreductase SCO5893 218 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223343 Nonpathogen - hypothetical protein 2SCK3130c SCO4970 1 None None None 21219704 Common - tetR-family transcriptional regulator SCO1193 33 COG1309 AcrR, Transcriptional regulator Transcription 21219669 Common - hypothetical protein SCO1156 10 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21225994 Nonpathogen - hypothetical protein SCO7735 2 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21221772 Nonpathogen - glycine-rich secreted protein SCO3342 1 None None None 21222853 Nonpathogen - hypothetical protein SCO4466 3 None None None 21225097 Common - hypothetical protein SCO6804 14 COG3801 COG3801, Uncharacterized protein conserved in bacteria Function unknown 21223925 Common - hypothetical protein SCO5569 28 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 21220110 Common - glutamine synthetase SCO1613 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 21225125 Common - probable isobutyryl-CoA mutase, small subunit SCO6833 109 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 21224092 Common - hypothetical protein SCO5746 122 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 21220934 Common - secreted protein SCO2471 22 COG2138 COG2138, Uncharacterized conserved protein Function unknown 32141199 Common - tryptophanyl-tRNA synthetase SCO3334 221 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21221032 Common - oxidoreductase SCO2573 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 21220294 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase SCO1804 171 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 21223670 Nonpathogen - hypothetical protein SCO5307 3 None None None 21220735 Common - methionine aminopeptidase SCO2266 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 21218701 Common - hypothetical protein SCO0142 49 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 21223169 Common - two-component system sensor kinase SCO4791 34 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223570 Common - moaE-like protein SCO5201 158 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 21222359 Common - short chain dehydrogenase SCO3954 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21222609 Common - hypothetical protein SCO4213 40 COG1715 Mrr, Restriction endonuclease Defense mechanisms 21221602 Common - hypothetical protein SCO3165 106 COG2606 EbsC, Uncharacterized conserved protein Function unknown 21222862 Common - cytochrome biogenesis related protein SCO4475 83 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 21219715 Nonpathogen - hypothetical protein 2SCG5805 SCO1205 1 None None None 21220218 Common - serine/threonine protein kinase SCO1724 136 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21220266 Nonpathogen - regulatory protein SCO1774 4 COG0457 NrfG, FOG: TPR repeat General function prediction only 21223966 Common - transcriptional regulator SCO5611 12 COG1396 HipB, Predicted transcriptional regulators Transcription 21218863 Common - decarboxylase SCO0315 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 21222896 Nonpathogen - integral membrane protein SCO4511 1 None None None 21222448 Common - integral membrane protein SCO4045 32 COG3247 HdeD, Uncharacterized conserved protein Function unknown 21225831 Common - oligopeptide ABC transporter ATP-binding protein SCO7567 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 21222227 Common - branched-chain alpha keto acid dehydrogenase E1 alpha subunit SCO3817 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 21220308 Nonpathogen - integral membrane protein SCO1819 4 COG2261 COG2261, Predicted membrane protein Function unknown 21224416 Common - transport system integral membrane protein SCO6087 149 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219483 Common - hypothetical protein SCO0965 36 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 21223462 Common - cyclase SCO5091 87 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21220809 Common - hypothetical protein SCO2341 7 None None None 21220956 Common - hypothetical protein SCO2493 71 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 21221044 Common proA gamma-glutamyl phosphate reductase SCO2585 191 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 21219230 Common - regulator SCO0703 6 None None None 21223284 Nonpathogen - hypothetical protein SCO4910 1 None None None 21224960 Common - transcriptional regulator SCO6664 47 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21223510 Common - dihydropteroate synthase SCO5141 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 21219497 Common - hypothetical protein SCO0980 122 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 21224476 Common - ADA-like regulatory protein SCO6150 85 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 21224528 Common - catalase SCO6204 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 21220944 Common - hypothetical protein SCO2481 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 21225819 Common - solute binding lipoprotein SCO7555 40 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21218966 Nonpathogen - hypothetical protein SCO0424 1 None None None 21219529 Common - oxidoreductase SCO1012 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21224345 Common - ABC transporter ATP-binding protein SCO6010 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 21221293 Common - N-acetylglucosamine-6-phosphate deacetylase SCO2843 110 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 21220600 Common - hypothetical protein SCO2122 155 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21221628 Common - hypothetical protein SCO3193 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222599 Common - hypothetical protein SCO4203 14 None None None 21224920 Common - ATP/GTP binding protein SCO6622 23 COG3410 COG3410, Uncharacterized conserved protein Function unknown 21224577 Common - transcriptional regulator SCO6256 129 COG2188 PhnF, Transcriptional regulators Transcription 21224837 Common - nitrate reductase alpha chain NarG SCO6535 110 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 21220949 Common - nitrite reductase NirB SCO2486 226 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 21221627 Common - integral membrane protein SCO3192 29 COG4292 COG4292, Predicted membrane protein Function unknown 21221965 Nonpathogen - small secreted protein SCO3546 2 None None None 21225679 Common - binding-protein dependent transport protein SCO7409 163 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219394 Nonpathogen - hypothetical protein SCO0873 1 None None None 21223586 Common - integral membrane protein SCO5218 120 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 21223892 Common - ATP/GTP binding protein SCO5537 29 COG2229 COG2229, Predicted GTPase General function prediction only 21223323 Common - nitrate reductase gamma chain NarI3 SCO4950 55 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 21223937 Common - hypothetical protein SCO5581 5 None None None 21218659 Nonpathogen - transposase SCO0090 4 None None None 21222331 Common - transcriptional regulator SCO3925 43 COG1414 IclR, Transcriptional regulator Transcription 21223004 Nonpathogen - sporulation-related protein SCO4621 1 None None None 21220860 Common - aldose 1-epimerase SCO2393 94 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 21225240 Nonpathogen - hypothetical protein SCO6953 1 None None None 21222348 Common - transcriptional regulator SCO3943 122 COG1609 PurR, Transcriptional regulators Transcription 21218996 Common - binding-protein dependent transport protein SCO0455 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219643 Common - secreted deacetylase SCO1129 120 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21226022 Common - hypothetical protein SCO7768 12 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 21225597 Common - hypothetical protein SCO7321 22 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220514 Common - citrate lyase beta chain SCO2033 99 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 21223225 Common - integral membrane protein SCO4849 93 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 21224188 Common - hypothetical protein SCO5844 36 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 21224286 Common - oxidoreductase SCO5948 73 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21225742 Common - phenylacetic acid degradation protein PaaD SCO7474 72 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 21225440 Common - hypothetical protein SCO7160 44 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 21221533 Common - hypothetical protein SCO3094 26 COG1507 COG1507, Uncharacterized conserved protein Function unknown 21221103 Common - integral membrane protein SCO2646 23 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 21225859 Common - integral membrane transport protein SCO7596 51 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 21225354 Nonpathogen - hypothetical protein SCO7071 1 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 21219377 Common - integral membrane protein SCO0856 8 None None None 21223657 Common - ATP/GTP-binding protein SCO5292 32 COG2229 COG2229, Predicted GTPase General function prediction only 32141328 Common - anti-sigma factor SCO7322 33 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21223918 Common - thiamine monophosphate kinase SCO5562 178 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 21225361 Common - insertion element transposase (fragment) SCO7078 42 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21223875 Common - hypothetical protein SCO5519 121 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 21222046 Nonpathogen - hypothetical protein SCO3631 1 None None None 21219047 Common - dehydrogenase (secreted protein) SCO0511 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21218795 Common - hypothetical protein SCO0242 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21224161 Common - DNA hydrolase with mutT domain SCO5817 68 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21225225 Common - probable acyl-CoA dehydrogenase SCO6938 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21223421 Common - secreted protein SCO5048 6 None None None 21224168 Common - two-component sensor SCO5824 66 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21224402 Nonpathogen - hypothetical protein SCO6072 4 None None None 21218754 Common - hypothetical protein SCO0198 12 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21223740 Nonpathogen - hypothetical protein SCO5380 1 None None None 21223177 Common - secreted lipase SCO4799 36 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 21223851 Common - phosphodiesterase SCO5495 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 21218987 Common - secreted protein SCO0445 6 None None None 21219215 Common - hypothetical protein SCO0686 118 COG1295 Rbn, Predicted membrane protein Function unknown 21224142 Common - secreted protein SCO5797 13 None None None 21218648 Nonpathogen - hypothetical protein SCO0074 1 None None None 21220137 Common - transport protein SCO1641 20 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21223073 Nonpathogen - hypothetical protein SCO4693 1 None None None 21218982 Common - integral membrane protein SCO0440 28 COG3819 COG3819, Predicted membrane protein Function unknown 21225560 Common - hydroxylase SCO7283 39 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21220003 Nonpathogen - secreted protein SCO1502 3 None None None 21223311 Common - hypothetical protein SCO4937 10 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21218708 Nonpathogen - hypothetical protein SCO0150 3 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21220104 Common - serine protease (membrane protein) SCO1607 109 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21223250 Common - sugar translocase SCO4876 7 COG2246 COG2246, Predicted membrane protein Function unknown 21220320 Common - oxidoreductase SCO1831 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221686 Nonpathogen - SpdD protein SCO3253 1 None None None 21224889 Common - elongation factor G SCO6589 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 21221394 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase SCO2949 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 21219940 Common - hypothetical protein SCO1437 6 None None None 21224598 Common - diaminobutyrate-pyruvate aminotransferase SCO6279 234 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 21218664 Common - transposase SCO0098 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219555 Common - ROK family regulatory protein SCO1039 154 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21219579 Common - sugar transport integral membrane protein SCO1064 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21225252 Common - hypothetical protein SCO6965 11 None None None 21224842 Common phhB pterin-4-alpha-carbinolamine dehydratase SCO6540 51 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 21225334 Common rho transcription termination factor Rho SCO7051 201 COG1158 Rho, Transcription termination factor Transcription 21224137 Nonpathogen - transmembrane protein SCO5792 1 None None None 21221452 Common - hypothetical protein SCO3009 81 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 21220202 Common - ABC sugar transporter, ATP-binding subunit SCO1707 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 21225627 Common - hypothetical protein SCO7353 201 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 21219847 Nonpathogen - lipoprotein SCO1341 1 None None None 21225838 Nonpathogen - hypothetical protein SCO7574 1 None None None 21222078 Nonpathogen - regulatory protein SCO3664 5 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219296 Common - ferredoxin SCO0773 11 COG1141 Fer, Ferredoxin Energy production and conversion 21221197 Common - probable LacI-family transcriptional regulator SCO2745 129 COG1609 PurR, Transcriptional regulators Transcription 21219570 Common - aminotransferase SCO1054 228 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 21224988 Common - transcriptional regulator SCO6694 27 COG1309 AcrR, Transcriptional regulator Transcription 21224363 Common - uroporphyrinogen decarboxylase SCO6031 174 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 21225675 Common - hypothetical protein SCO7404 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21219017 Common - hypothetical protein SCO0477 40 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21220664 Common - hypothetical protein SCO2190 106 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 21219007 Common - hypothetical protein SCO0467 23 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 21223542 Common - hypothetical protein SCO5173 9 None None None 21218957 Nonpathogen - membrane protei SCO0415 1 None None None 21222741 Common - integrase SCO4350 14 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 21224314 Common - amino acid permease SCO5977 147 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21221190 Common - deoxyribonuclease SCO2737 137 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 21220939 Common - dehydrogenase/reductase (secreted protein) SCO2476 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21224037 Common - transport system integral membrane protein SCO5688 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21223162 Nonpathogen - hypothetical protein SCO4783 1 None None None 21223594 Common - ribonucleotide-diphosphate reductase large chain SCO5226 222 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 21221339 Common - secreted protein SCO2892 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21222149 Common - lipoprotein SCO3737 14 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 21222161 Nonpathogen - integral membrane protein SCO3749 1 None None None 21219893 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase SCO1389 199 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 21220080 Common - secreted arabinosidase SCO1583 20 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 21222070 Common - spermidine synthase SCO3655 118 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 21221574 Common - galactokinase SCO3136 86 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 21219510 Common - hypothetical protein SCO0993 36 COG0439 AccC, Biotin carboxylase Lipid metabolism 21218944 Common - glutamate-1-semialdehyde 2,1-aminomutase SCO0401 236 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 21219573 Common - sugar transport integral membrane protein SCO1058 187 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21220757 Common - hypothetical protein SCO2288 4 None None None 21224965 Common - transcriptional regulator SCO6669 116 COG1414 IclR, Transcriptional regulator Transcription 21224025 Common - hypothetical protein SCO5675 2 None None None 21219553 Common - hypothetical protein SCO1037 32 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 21223539 Common - tetR-family transcriptional regulator SCO5170 105 COG1309 AcrR, Transcriptional regulator Transcription 21226019 Common - transcriptional regulator SCO7765 23 COG1846 MarR, Transcriptional regulators Transcription 21223998 Common - ABC transporter integral membrane protein SCO5647 133 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 21218896 Common - solute-binding protein SCO0352 42 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21221672 Common - hypothetical protein SCO3239 26 COG1099 COG1099, Predicted metal-dependent hydrolases with the TIM-barrel fold General function prediction only 21222702 Nonpathogen - hypothetical protein SCO4309 2 None None None 21222324 Common - hypothetical protein SCO3917 25 COG2153 ElaA, Predicted acyltransferase General function prediction only 21218716 Common - ECF sigma factor SCO0159 74 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21222315 Common rpsR 30S ribosomal protein S18 SCO3908 213 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 21219534 Common - lipoprotein SCO1017 5 None None None 21220279 Common - iron-siderophore uptake system transmembrane component SCO1787 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 21220511 Common - hypothetical protein SCO2030 2 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21220965 Common - glycyl-tRNA synthetase SCO2504 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 21223105 Common rpmJ 50S ribosomal protein L36 SCO4726 134 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 21225013 Common - UvrA-like ABC transporter SCO6719 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 21218689 Nonpathogen - hypothetical protein SCO0129 1 None None None 21223434 Common - hypothetical protein SCO5062 2 None None None 21219539 Nonpathogen - hypothetical protein SCO1023 2 None None None 32141206 Common - hypothetical protein SCO3500 5 None None None 21222341 Common - plasmid replication initiator protein SCO3936 5 None None None 21224844 Common - secreted glycosyl hydrolase SCO6542 14 None None None 32141285 Nonpathogen - transferase SCO6077 6 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 21225028 Common - L-asparagine permease SCO6734 143 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 21225792 Common - DeoR-family transcriptional regulator SCO7527 43 COG2378 COG2378, Predicted transcriptional regulator Transcription 21222928 Common - hypothetical protein SCO4544 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21218856 Nonpathogen - hypothetical protein SCO0308 1 None None None 21221431 Common - regulatory protein SCO2987 118 COG1846 MarR, Transcriptional regulators Transcription 21220178 Common - amino acid permease SCO1683 33 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21223659 Common - secreted protein SCO5294 104 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21221306 Common - hypothetical protein SCO2856 37 COG3832 COG3832, Uncharacterized conserved protein Function unknown 21223926 Common - hypothetical protein SCO5570 41 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 21221074 Common clpX ATP-dependent protease ATP-binding subunit SCO2617 229 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 21220087 Common - secreted protein SCO1590 38 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 21220609 Common - glycosyl transferase SCO2132 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21224003 Common - hypothetical protein SCO5652 44 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 21221591 Common - integral membrane protein SCO3154 34 COG1928 PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase Posttranslational modification, protein turnover, chaperones 21222761 Common - hypothetical protein SCO4371 13 None None None 21220317 Common - hypothetical protein SCO1828 12 None None None 21224105 Common - hypothetical protein SCO5759 47 COG3832 COG3832, Uncharacterized conserved protein Function unknown 21221183 Common - acetyltransferase SCO2729 135 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21223351 Common - integral membrane protein SCO4978 107 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 21221505 Common - peptide transporter SCO3064 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 21225540 Common - chitinase SCO7263 19 COG3179 COG3179, Predicted chitinase General function prediction only 21220799 Common - MarR-family transcriptional regulator SCO2331 10 COG1846 MarR, Transcriptional regulators Transcription 21219641 Common - oxidoreductase SCO1127 90 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21220265 Common - L-alanine dehydrogenase SCO1773 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 21225920 Common - oxidoreductase SCO7659 47 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21222901 Nonpathogen - hypothetical protein SCO4516 1 None None None 21225368 Common - MerR-family transcriptional regulator SCO7086 100 COG0789 SoxR, Predicted transcriptional regulators Transcription 21224649 Nonpathogen - hypothetical protein SCO6336 2 None None None 21221889 Common - hypothetical protein SCO3464 52 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 21223257 Common - peptidase SCO4883 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 21222368 Common - hypothetical protein SCO3963 51 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 21221059 Nonpathogen - integral membrane protein SCO2601 2 None None None 21225108 Common - ABC transporter permease protein SCO6815 222 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 21225829 Common - oligopeptide ABC transporter integral membrane protein SCO7565 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21221226 Common - tetR-family regulatory protein SCO2775 72 COG1309 AcrR, Transcriptional regulator Transcription 31340551 Common - xylanase SCO1883 40 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 21219977 Common - primosome assembly protein PriA SCO1475 194 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 21222693 Common - hypothetical protein SCO4300 5 None None None 32141218 Common - transcriptional regulator SCO3864 108 COG2188 PhnF, Transcriptional regulators Transcription 21220693 Common - hypothetical protein SCO2221 25 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 21225953 Common - oxidoreductase SCO7693 150 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221561 Common - ribose-phosphate pyrophosphokinase SCO3123 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 21218673 Nonpathogen - hypothetical protein SCO0109 1 None None None 21225201 Nonpathogen - hypothetical protein SCO6913 1 None None None 21224784 Common - hypothetical protein SCO6480 9 COG1359 COG1359, Uncharacterized conserved protein Function unknown 21224909 Common - hypothetical protein SCO6611 7 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21221387 Common - hypothetical protein SCO2941 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 32141197 Common - hypothetical protein SCO3284 61 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221231 Nonpathogen - secreted protein SCO2780 4 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 21221928 Common - integral membrane efflux protein SCO3507 111 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225213 Nonpathogen - hypothetical protein (membrane protein) SCO6925 1 None None None 21220285 Common - hypothetical protein SCO1794 113 COG1881 COG1881, Phospholipid-binding protein General function prediction only 21219443 Common - cytochrome B subunit SCO0924 30 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 21224701 Nonpathogen - hypothetical protein SCO6389 1 None None None 21219624 Common - secreted lyase SCO1110 13 None None None 21226034 Common - probable IS110 transposase SCO7782 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220679 Nonpathogen - hypothetical secreted protein SCO2207 1 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 21221278 Common - probable amino acid ABC transporter protein, solute-binding component SCO2828 130 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 21220854 Common - ACP S-malonyltransferase SCO2387 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 21224229 Common - acyl carrier protein SCO5887 35 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21220448 Common - integral membrane export protein SCO1963 89 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 21224737 Common - hypothetical protein SCO6430 44 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 21222951 Common - NADH dehydrogenase subunit G SCO4568 201 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 21225528 Nonpathogen - hypothetical protein SCO7251 2 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 21222987 Nonpathogen - NADH dehydrogenase subunit NuoJ2 SCO4604 3 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 21224215 Common - turgor pressure regulator SCO5872 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21222129 Common - cation transport system component SCO3716 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 21225503 Common - integral membrane protein SCO7226 17 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21220068 Common - argininosuccinate lyase SCO1570 228 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 21220597 Common - 6-phosphofructokinase SCO2119 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 21222675 Nonpathogen - dimeric protein SCO4282 1 None None None 21225664 Nonpathogen - lipoprotein SCO7393 3 None None None 21219157 Nonpathogen - transporter protein SCO0625 6 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 21224240 Common - hypothetical protein SCO5899 37 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21219449 Common - lipoprotein SCO0930 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 21220387 Common - integral membrane sugar transport protein SCO1900 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219855 Common - hypothetical protein SCO1349 17 None None None 21224531 Nonpathogen - hypothetical protein SCO6207 1 COG0011 COG0011, Uncharacterized conserved protein Function unknown 21221876 Nonpathogen - hypothetical protein SCO3451 2 None None None 32141302 Common - SIR2 family transcriptional regulator SCO6464 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 21224024 Nonpathogen - integral membrane protein SCO5674 1 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21225807 Common - secreted protein SCO7542 3 None None None 21225172 Nonpathogen - ATP-binding protein SCO6881 2 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 21221315 Nonpathogen - hypothetical protein SCO2866 1 None None None 21225933 Common - lipoprotein SCO7673 32 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 21222943 Common - polypetide deformylase SCO4560 209 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 21224426 Common - sulfate adenylyltransferase subunit 1 SCO6097 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 21219408 Common - secreted protein SCO0888 121 COG0431 COG0431, Predicted flavoprotein General function prediction only 21220338 Common cobN cobaltochelatase SCO1849 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 21222457 Common - integral membrane protein SCO4054 2 None None None 21222381 Common - protease (secreted protein) SCO3977 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21225988 Common - hypothetical protein SCO7729 142 COG1741 COG1741, Pirin-related protein General function prediction only 21224057 Common truB tRNA pseudouridine synthase B SCO5709 243 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 21222911 Common - protein kinase SCO4526 173 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 21224376 Common - hypothetical protein SCO6045 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 21225535 Common - hypothetical protein SCO7258 121 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 21219132 Common - regulator of sig8 SCO0599 7 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220441 Common - transcriptional regulator (lacI family) SCO1956 126 COG1609 PurR, Transcriptional regulators Transcription 21220207 Nonpathogen - hypothetical protein SCO1713 1 None None None 21221944 Nonpathogen - hypothetical protein SCO3523 1 None None None 21224609 Common - hypothetical protein SCO6290 25 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 21222505 Common - integral membrane protein SCO4104 133 COG2860 COG2860, Predicted membrane protein Function unknown 21219477 Common - secreted protein SCO0959 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 21219470 Common - solute-binding protein SCO0952 88 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21218736 Common - zinc-containing dehydrogenase SCO0179 210 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21221736 Common - hypothetical protein SCO3305 94 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 21222377 Nonpathogen - hypothetical protein SCO3973 1 None None None 21222338 Common - gntR-family transcriptional regulator SCO3932 115 COG2188 PhnF, Transcriptional regulators Transcription 21219198 Common - flavoprotein SCO0668 171 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21221790 Common - AsnC-family transcriptional regulator SCO3361 153 COG1522 Lrp, Transcriptional regulators Transcription 21224195 Common - integral membrane protein SCO5851 8 COG2510 COG2510, Predicted membrane protein Function unknown 21220077 Common argC N-acetyl-gamma-glutamyl-phosphate reductase SCO1580 213 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 21225763 Nonpathogen - integral membrane protein SCO7496 3 COG0730 COG0730, Predicted permeases General function prediction only 21221186 Common - hypothetical protein SCO2733 60 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21224036 Common - transport system integral membrane protein SCO5687 140 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 21224904 Common - hypothetical protein SCO6606 12 None None None 21221725 Common - small integral membrane protein SCO3293 2 None None None 21222116 Common - substrate binding protein SCO3703 13 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 21219285 Common - hypothetical protein SCO0761 5 None None None 21224114 Nonpathogen - hypothetical protein SCO5768 1 None None None 21224327 Nonpathogen - hypothetical protein SCO5990 1 None None None 21219369 Common - oxidoreductase SCO0848 65 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21220817 Common - hypothetical protein SCO2349 24 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 21225658 Nonpathogen - integral membrane protein SCO7385 1 None None None 21223991 Nonpathogen - hypothetical protein SCO5640 1 None None None 21222712 Nonpathogen - hypothetical protein SCO4320 1 None None None 21220160 Common - hypothetical protein SCO1664 18 None None None 21222287 Common rpmH 50S ribosomal protein L34 SCO3880 191 None None None 21221973 Common - integral membrane protein SCO3554 4 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 21223823 Common - hypothetical protein SCO5465 37 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 21221642 Common - tetR-family transcriptional regulator (fragment) SCO3207 37 COG1309 AcrR, Transcriptional regulator Transcription 21221178 Common - amino acid transporter SCO2724 83 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21221545 Nonpathogen - lipoprotein SCO3106 3 None None None 21225510 Nonpathogen - secreted protein SCO7233 6 None None None 21222103 Common - hydrolase SCO3690 126 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225788 Common - DNA ligase SCO7522 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 21218620 Nonpathogen - integral membrane protein SCO0041 1 None None None 21221798 Common - large ATP-binding protein SCO3369 14 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 21223180 Common - hypothetical protein SCO4802 15 None None None 21220075 Common argD acetylornithine aminotransferase SCO1577 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 21223393 Nonpathogen - hypothetical protein SCO5020 1 None None None 21219960 Common - asnC-family regulatory protein SCO1458 148 COG1522 Lrp, Transcriptional regulators Transcription 21220829 Common - hypothetical protein SCO2361 11 None None None 21223581 Common - integral membrane protein SCO5213 9 None None None 21220361 Common - acetyltransferase SCO1873 39 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 32141339 Common - hypothetical protein SCO7628 108 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 21219122 Common - lysR-family transcriptional regulator SCO0589 185 COG0583 LysR, Transcriptional regulator Transcription 21221825 Common - dihydropteroate synthase SCO3398 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 21224798 Common - dehydrogenase SCO6495 40 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21219116 Common - cytochrome P450 SCO0583 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21221521 Nonpathogen - secreted protein SCO3080 1 None None None 21223556 Common - glutaredoxin-like protein SCO5187 36 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 21220521 Common - hypothetical protein SCO2040 11 None None None 21219883 Common - glycine dehydrogenase SCO1378 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 32141251 Common - tetR-family transcriptional regulator SCO4940 26 COG1309 AcrR, Transcriptional regulator Transcription 32141114 Common - large, multifunctional secreted protein SCO0505 35 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 21224718 Nonpathogen - DNa-binding protein SCO6410 2 COG1396 HipB, Predicted transcriptional regulators Transcription 21220561 Common - hypothetical protein SCO2081 161 COG1496 COG1496, Uncharacterized conserved protein Function unknown 21222242 Common - transcriptional regulator SCO3833 107 COG1309 AcrR, Transcriptional regulator Transcription 21219182 Nonpathogen - gas vesicle synthesis protein SCO0652 1 None None None 21225152 Common - protein kinase-like protein SCO6861 152 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21222209 Common - chromosome condensation protein SCO3798 137 COG1741 COG1741, Pirin-related protein General function prediction only 21222217 Common - hydrolase SCO3807 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 21218740 Common - deoxiribopirymidine photolyase SCO0183 142 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 21220211 Nonpathogen - hypothetical protein SCO1717 4 None None None 21223642 Common - ATP/GTP binding protein SCO5275 36 None None None 21222980 Common - two-component system sensor kinase SCO4597 70 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220355 Common - hydroxylase SCO1867 35 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 21219504 Common - integral membrane protein SCO0987 62 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 21221884 Nonpathogen - hypothetical potein SCE4616c SCO3459 1 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21225519 Nonpathogen - hypothetical protein SCO7242 1 None None None 21223144 Common - hypothetical protein SCO4765 58 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 21224663 Common - hypothetical protein SCO6350 8 COG1309 AcrR, Transcriptional regulator Transcription 21221693 Common - MutT-like protein SCO3260 82 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21221572 Common - two-component system response regulator SCO3134 160 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21222444 Common upp uracil phosphoribosyltransferase SCO4041 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 32141105 Common - substrate binding protein SCO0273 77 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21225663 Common - hypothetical protein SCO7392 6 None None None 21224934 Nonpathogen - hypothetical protein SCO6637 2 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 21222727 Nonpathogen - hypothetical protein SCO4335 1 None None None 21220568 Common - putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- D-alanyl-alanyl ligase SCO2088 210 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 21220789 Nonpathogen - secreted protein SCO2321 8 COG5029 CAL1, Prenyltransferase, beta subunit Posttranslational modification, protein turnover, chaperones 21221963 Nonpathogen - hypothetical protein SCO3544 1 None None None 21222958 Common - NADH dehydrogenase subunit N SCO4575 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 21224411 Common - glycogen debranching enzyme SCO6082 153 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 21220159 Common cysS cysteinyl-tRNA synthetase SCO1663 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21223328 Common - ATP/GTP-binding protein SCO4955 25 None None None 21220054 Common - methyltransferase SCO1555 33 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 21220169 Common - hypothetical protein SCO1673 3 None None None 21220792 Common - ABC transporter ATP-binding subunit SCO2324 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 21226087 Nonpathogen - hypothetical protein SCO7838 1 None None None 21221659 Common - ABC transporter ATP-binding protein SCO3224 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21219871 Common - hypothetical protein SCO1366 73 COG1695 COG1695, Predicted transcriptional regulators Transcription 21224523 Common - secreted esterase SCO6199 7 None None None 21221800 Common - hypothetical protein SCO3371 7 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 21219401 Common - hypothetical protein SCO0881 131 COG1741 COG1741, Pirin-related protein General function prediction only 21224579 Common - sugar ABC transporter permease protein SCO6258 108 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 21225905 Common - ATP binding protein SCO7644 54 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 32141124 Common - hydrolase SCO0790 93 COG0546 Gph, Predicted phosphatases General function prediction only 21223261 Common - sugar ABC transporter integral membrane protein SCO4887 99 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 21224867 Common - transcriptional regulator SCO6565 110 COG1802 GntR, Transcriptional regulators Transcription 32141118 Common - tellurium resistance protein SCO0641 29 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21225276 Common - membrane transport protein SCO6990 71 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 21219850 Common - solute binding transport lipoprotein SCO1344 186 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21223857 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B SCO5501 211 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 21224171 Common - transmembrane transport protein SCO5827 114 COG4147 DhlC, Predicted symporter General function prediction only 21225143 Nonpathogen - hypothetical protein SCO6852 1 None None None 21224700 Nonpathogen - hypothetical protein SCO6388 1 None None None 21221532 Common - hydrolase SCO3093 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 21224458 Common - carboxypeptidase SCO6131 103 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 21224996 Common - 3-oxoadipate CoA-transferase subunit B SCO6702 96 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 31340548 Common - two-component system sensor kinase SCO1802 146 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 32141153 Common - hypothetical protein SCO2023 57 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 21223423 Common - nucleotide-sugar dehydrogenase SCO5050 180 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 21223153 Common - glycerol phosphate dehydrogenase SCO4774 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 21220972 Nonpathogen - hypothetical protein SCO2511 1 None None None 21219701 Common - export protein SCO1190 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221083 Common - DNA repair hydrolase (fragment) SCO2626 165 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 21223945 Nonpathogen - hypothetical protein SCO5590 1 None None None 21224358 Common - fatty acid oxidation complex alpha-subunit SCO6026 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21220426 Common - secreted protein SCO1940 20 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 21220867 Nonpathogen - hypothetical protein SCO2400 1 COG5386 COG5386, Cell surface protein Cell envelope biogenesis, outer membrane 21225239 Common - hypothetical protein SCO6952 8 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 21221754 Common - RNA polymerase sigma factor SCO3323 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21218783 Common - tetR-family transcriptional regulator SCO0230 71 COG1309 AcrR, Transcriptional regulator Transcription 21224600 Common - FAD-binding protein SCO6281 39 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21224178 Nonpathogen - hypothetical protein SCO5834 1 None None None 21221710 Nonpathogen - phosphotransferase SCO3277 4 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 21224466 Common - two-component system response regulator SCO6140 211 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225633 Common - hydrolase SCO7359 110 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21224176 Common - citrate synthase SCO5832 194 COG0372 GltA, Citrate synthase Energy production and conversion 21222884 Common - tetR-family regulatory protein SCO4499 98 COG1309 AcrR, Transcriptional regulator Transcription 21221852 Common - 30S ribosomal protein S18 SCO3425 96 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 21218821 Common - hypothetical protein SCO0270 9 None None None 21220332 Common - secreted protein SCO1843 12 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21225391 Common - oxidoreductase SCO7109 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 21219935 Nonpathogen - membrane protein SCO1432 6 None None None 21221258 Nonpathogen - integral membrane protein SCO2807 6 None None None 21223681 Common - polyketide beta-ketoacyl synthase alpha SCO5318 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21221273 Common - decarboxylase SCO2823 45 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 21224655 Nonpathogen - hypothetical protein SCO6342 1 None None None 21219969 Nonpathogen - hypothetical protein SCO1467 5 None None None 21222277 Common - WD-40 repeat protein SCO3869 80 COG2319 COG2319, FOG: WD40 repeat General function prediction only 21220098 Common - hypothetical protein SCO1601 9 None None None 21220329 Common - ABC transporter ATP binding protein SCO1840 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21224018 Common - polyamine ABC transporter ATP-binding protein SCO5668 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 21223752 Common - ABC transporter integral membrane subunit SCO5392 8 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 21222791 Common - lipoprotein SCO4401 3 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 21225406 Common aceE pyruvate dehydrogenase subunit E1 SCO7124 154 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 21224820 Common - transcriptional regulator SCO6518 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21223784 Common - acetate kinase SCO5424 162 COG0282 ackA, Acetate kinase Energy production and conversion 21219239 Common - lipase (secreted protein) SCO0713 4 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 21224878 Common - hypothetical protein SCO6577 24 COG1099 COG1099, Predicted metal-dependent hydrolases with the TIM-barrel fold General function prediction only 21225324 Nonpathogen - hypothetical protein SCO7041 3 None None None 21221267 Common - hypothetical protein SCO2817 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 21221953 Nonpathogen - hypothetical protein SCO3532 1 None None None 21219877 Common - integral membrane protein SCO1372 16 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 21226002 Nonpathogen - hypothetical protein SCO7743 1 None None None 21224728 Common - two-component system sensor kinase SCO6421 59 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21225268 Common - hypothetical protein SCO6982 58 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21222521 Common - MarR-family transcriptional regulator SCO4122 69 COG1846 MarR, Transcriptional regulators Transcription 21221356 Nonpathogen - hypothetical protein SCO2909 1 None None None 21219833 Common - integral membrane protein SCO1327 33 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 32141129 Nonpathogen - hypothetical protein SCO1021 1 None None None 21222275 Nonpathogen - ferredoxin SCO3867 1 COG1141 Fer, Ferredoxin Energy production and conversion 32141330 Common - nitrate reductase NarB (fragment) SCO7374 189 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 32141292 Common - serine/threonine protein kinase SCO6219 13 None None None 21224284 Nonpathogen - hypothetical protein SCO5946 3 COG3619 COG3619, Predicted membrane protein Function unknown 21225204 Nonpathogen - secreted protein SCO6916 1 None None None 21221637 Common - RNA polymerase principal sigma factor SCO3202 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 21219953 Common - endoglucanase precursor SCO1451 15 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 21222753 Common - two component system sensor kinase SCO4362 112 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21222621 Nonpathogen - integral membrane protein SCO4225 1 None None None 21222616 Common - hypothetical protein SCO4220 14 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21224871 Common - oxidoreductase SCO6570 129 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21221066 Common - penicillin binding protein SCO2608 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21222844 Common - membrane-associated oxidoreductase SCO4456 6 None None None 21224615 Common - hypothetical protein SCO6296 29 COG0824 FcbC, Predicted thioesterase General function prediction only 21221119 Common - secreted protein SCO2663 6 None None None 21224355 Common - hypothetical protein SCO6023 20 None None None 21223136 Common - hypothetical protein SCO4757 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 21222192 Nonpathogen - secreted protein SCO3781 1 None None None 21223337 Common - integral membrane transport protein SCO4964 52 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21219440 Common - hypothetical protein SCO0921 60 COG3176 COG3176, Putative hemolysin General function prediction only 21221494 Common - UDP-glucose 6-dehydrogenase SCO3052 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 21221289 Nonpathogen - lipoprotein SCO2839 1 None None None 21219356 Common - methyltransferase SCO0835 33 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221151 Common - 2-hydroxyacid-family dehydrogenase SCO2696 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 21221764 Common - hydrolase SCO3333 180 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 21225853 Common - catalase SCO7590 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 21220376 Common - dihydropicolinate synthase SCO1889 219 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 21222233 Common - quinone oxidoreductase SCO3823 196 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21225464 Common - branched amino acid binding secreted protein SCO7185 97 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 21225638 Common - TetR-family transcriptional regulator SCO7364 27 COG1309 AcrR, Transcriptional regulator Transcription 21218950 Common - probable methyltransferase SCO0408 30 COG0500 SmtA, SAM-dependent methyltransferases Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21223803 Common - hypothetical protein SCO5445 14 COG4762 COG4762, Uncharacterized protein conserved in bacteria Function unknown 21221807 Nonpathogen - small membrane protein SCO3378 1 None None None 21220822 Nonpathogen - hypothetical protein SCO2354 1 None None None 21221984 Nonpathogen - integral membrane transport protein SCO3565 1 None None None 21223609 Nonpathogen - integral membrane protein SCO5242 1 None None None 21223600 Common - sugar transporter sugar binding protein SCO5232 77 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 32141317 Common - hypothetical protein SCO6929 9 None None None 21222210 Nonpathogen - hypothetical protein SCO3799 1 None None None 21220330 Common - hypothetical protein SCO1841 26 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 21224970 Nonpathogen - hypothetical protein SCO6674 1 None None None 21222839 Common - export protein SCO4451 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219251 Common - oxidoreductase SCO0726 17 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 21225445 Common - sugar-binding integral membrane transport protein SCO7165 138 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219613 Common - MarR-family regulatory protein SCO1098 74 COG1846 MarR, Transcriptional regulators Transcription 21223819 Nonpathogen - secreted protein SCO5461 2 None None None 21220373 Common - integral membrane transport protein SCO1886 163 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21223203 Nonpathogen - hypothetical protein SCO4826 1 None None None 21220619 Common - two component sensor kinase SCO2142 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21223120 Common - hypothetical protein SCO4741 25 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 21219128 Common - hypothetical protein SCO0595 24 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 21222475 Common - sensor kinase SCO4073 61 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 32141263 Common - glycogen phosphorylase SCO5444 141 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 21221550 Common - ABC transport system ATP-binding protein SCO3111 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21222825 Common - sodium-coupled permease SCO4437 145 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 21220832 Common - hypothetical protein SCO2364 27 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21219897 Common - acetyl-CoA synthetase SCO1393 201 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 32141231 Nonpathogen - hypothetical protein SCO4260 6 None None None 21222863 Common - hypothetical protein SCO4476 18 None None None 21225314 Common - binding-protein-dependent transport protein SCO7029 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21221421 Nonpathogen - hypothetical protein SCO2977 1 None None None 21220150 Common - two-component response regulator SCO1654 221 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220927 Common - ABC transporter SCO2464 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21223082 Common rplC 50S ribosomal protein L3 SCO4702 230 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 21223850 Common ligA NAD-dependent DNA ligase LigA SCO5494 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 21222398 Common - partial replication initiator protein SCO3995 4 None None None 21222566 Common - oxidoreductase SCO4169 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21223116 Common - integral membrane protein SCO4737 48 COG1808 COG1808, Predicted membrane protein Function unknown 21223271 Common - transcriptional regulator SCO4897 182 COG0583 LysR, Transcriptional regulator Transcription 21218637 Common - LacI family transcriptional regulator SCO0062 127 COG1609 PurR, Transcriptional regulators Transcription 21219204 Common - secreted endo-1,4-beta-xylanase SCO0674 38 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 21221238 Nonpathogen - hypothetical protein SCO2787 1 None None None 21225919 Nonpathogen - hypothetical protein SCO7658 1 None None None 21224509 Common - transferase SCO6185 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21225068 Nonpathogen - transcriptional regulator SCO6775 3 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 21220779 Nonpathogen - hypothetical protein SCO2311 4 None None None 21223173 Nonpathogen - integral membrane protein SCO4795 1 None None None 21222664 Common - NADP-dependent alcohol dehydrogenase SCO4271 146 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 21222986 Common - NADH dehydrogenase subunit NuoI2 SCO4603 176 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 21222768 Common - hypothetical protein SCO4378 11 None None None 21224538 Nonpathogen - hypothetical protein SCO6215 2 None None None 21219454 Common - secreted protein SCO0935 14 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 21224693 Common - lipoprotein SCO6381 5 None None None 21219147 Nonpathogen - hypothetical protein SCO0614 1 None None None 21224621 Common - hydroxylase SCO6303 170 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 21221389 Common - sugar transporter membrane protein SCO2944 156 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21221539 Common - nucleoside triphosphate pyrophosphohydrolase SCO3100 152 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 21222438 Common - RNA polymerase sigma factor SCO4035 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21225879 Common - hypothetical protein SCO7617 12 None None None 21222687 Common - hypothetical protein SCO4294 44 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 21225119 Common - polyketide synthase SCO6827 219 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21220349 Common - hypothetical protein SCO1861 64 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 21225349 Common - 2,4-dienoyl-CoA reductase (NADPH) SCO7066 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 21224586 Common - gamma-butyrolactone binding protein SCO6265 100 COG1309 AcrR, Transcriptional regulator Transcription 21219247 Common - glycosyl transferase SCO0721 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 21221123 Common - hypothetical protein SCO2667 21 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 21222141 Nonpathogen - regulatory protein SCO3729 5 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21222571 Nonpathogen - integral membrane protein SCO4174 1 None None None 21225342 Common - oxidoreductase SCO7059 127 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 32141224 Common - amino acid/metabolite permease SCO4097 89 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21224644 Common - hypothetical protein SCO6330 4 None None None 21221585 Common - ABC transporter ATP-binding subunit SCO3147 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21224047 Common - hypothetical protein SCO5698 11 COG0456 RimI, Acetyltransferases General function prediction only 21219326 Common - hypothetical protein SCO0804 17 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 21221408 Nonpathogen - hypothetical protein SCO2963 1 None None None 21221844 Common - ABC transporter transmembrane component SCO3417 30 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21219333 Common - sugar isomerase SCO0812 39 COG4952 COG4952, Predicted sugar isomerase Cell envelope biogenesis, outer membrane 21220391 Common - transcriptional regulator SCO1904 32 COG1309 AcrR, Transcriptional regulator Transcription 21220252 Common - transferase SCO1759 83 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21221326 Nonpathogen - membrane protein SCO2877 1 None None None 21221472 Common - L-lactate permease SCO3029 103 COG1620 LldP, L-lactate permease Energy production and conversion 21222546 Common - ABC transport system ATP-binding protein SCO4148 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21219768 Common - two-component system response regulator SCO1260 202 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223848 Common - short chain dehydrogenase SCO5492 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21222500 Common - probable tetR family transcriptional regulator SCO4099 37 None None None 21222088 Common - conserved secreted protein SCO3675 27 None None None 21220222 Common - gntR-family transcriptional regulator SCO1728 85 COG1725 COG1725, Predicted transcriptional regulators Transcription 21219906 Common - large secreted protein SCO1402 11 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21223988 Common - mutT-like protein SCO5637 117 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21219728 Common - transmembrane transport protein SCO1218 120 COG4147 DhlC, Predicted symporter General function prediction only 21224975 Nonpathogen - hypothetical protein SCO6679 3 None None None 21225622 Nonpathogen - hypothetical protein SCO7348 1 None None None 21223667 Common - sensor-like histidine kinase SCO5304 196 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21223954 Common - signal peptidase I SCO5599 62 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 21222415 Common - integral membrane protein SCO4012 2 None None None 21221902 Common - dehydrogenase SCO3478 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 21225641 Common - probable membrane efflux protein SCO7367 27 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 21224789 Nonpathogen - hypothetical protein SCO6485 4 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 21223062 Common - tautomerase SCO4682 11 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 21223874 Common - transcriptional regulator SCO5518 10 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21218913 Common - secreted protein SCO0369 23 None None None 21220380 Common - lyase SCO1893 7 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21223301 Common - ligase SCO4927 195 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 32141130 Common - alpha-xylosidase YicI SCO1055 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 21223115 Common - phospho-sugar mutase SCO4736 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 32141166 Common - tetracenomycin C efflux protein SCO2373 179 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21220762 Common - integral membrane protein SCO2293 43 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21224638 Common - tetR-family regulatory protein SCO6323 5 COG1309 AcrR, Transcriptional regulator Transcription 21225194 Common - hypothetical protein SCO6904 5 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 21220628 Common - cytochrome c oxidase subunit III SCO2151 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 21225975 Common - hypothetical protein SCO7716 6 None None None 21221846 Common - hypothetical protein SCO3419 13 COG1695 COG1695, Predicted transcriptional regulators Transcription 21225726 Nonpathogen - hypothetical protein SCO7457 1 None None None 21223886 Common - integral membrane protein SCO5531 20 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21220632 Common - cytochrome c oxidase subunit I SCO2155 162 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 21225005 Common - hypothetical protein SCO6711 45 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 21223215 Common - tryptophanyl-tRNA synthetase SCO4839 229 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21225061 Common - 1-deoxy-D-xylulose-5-phosphate synthase SCO6768 218 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 21224554 Common - beta-mannosidase SCO6232 44 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21221251 Common - two component system histidine kinase SCO2800 157 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21225015 Nonpathogen - integral membrane protein SCO6721 3 None None None 21224068 Common - hypothetical protein SCO5721 7 None None None 21222020 Nonpathogen - hypothetical protein SCO3604 1 None None None 21219775 Nonpathogen - acyl carrier protein SCO1267 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21218591 Nonpathogen - hypothetical protein SCO0009 1 None None None 21222595 Nonpathogen - hypothetical protein SCO4199 3 None None None 21224946 Nonpathogen - hypothetical protein SCO6649 18 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21221638 Common - phosphinothricin acetyltransferase SCO3203 123 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 21219026 Common - hydrolase SCO0488 24 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 21221935 Nonpathogen - ATP-binding protein SCO3514 3 None None None 21219207 Common - secreted chitosanase SCO0677 6 None None None 21222388 Nonpathogen - hypothetical protein SCO3984 1 None None None 21219225 Nonpathogen - hypothetical protein SCO0698 1 None None None 21218883 Common - dehydrogenase SCO0338 153 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 21222648 Common - hypothetical protein SCO4253 56 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 21219395 Common - integral membrane protein SCO0874 13 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 21224256 Common - hypothetical protein SCO5917 9 COG0789 SoxR, Predicted transcriptional regulators Transcription 21222423 Common - two component system response regulator SCO4020 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21223555 Common - hypothetical protein SCO5186 93 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 21219680 Common - conserved hypothetical protein 2SCG1102c SCO1168 31 COG4279 COG4279, Uncharacterized conserved protein Function unknown 21221391 Common - sugar transporter sugar-binding protein SCO2946 105 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 21225021 Nonpathogen - hypothetical protein SCO6727 1 None None None 21220469 Common - hypothetical protein SCO1986 14 None None None 21220874 Common - aldose 1-epimerase SCO2407 96 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 21219995 Common aroB 3-dehydroquinate synthase SCO1494 208 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 21225454 Common - regulator SCO7175 7 None None None 21220872 Common - sugar-transport ATP binding protein SCO2405 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 21225374 Nonpathogen - secreted protein SCO7092 1 None None None 21223199 Nonpathogen - integral membrane protein SCO4822 1 None None None 21220498 Common - monooxygenase SCO2016 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 21224148 Common - LexA repressor SCO5803 171 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 21222370 Common - secreted protein SCO3966 98 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 21225109 Common - ABC transporter binding lipoprotein SCO6816 138 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 21219480 Common - glycosyl transferase SCO0962 214 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21222016 Common - hypothetical protein SCO3600 7 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 21224233 Common - peptide synthase SCO5891 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21224486 Common - bifunctional preprotein translocase subunit SecD/SecF SCO6160 206 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 21223371 Common - hypothetical protein SCO4998 6 None None None 21222193 Nonpathogen - regulatory protein SCO3782 1 COG1396 HipB, Predicted transcriptional regulators Transcription 21225099 Common - phage integrase SCO6806 94 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 21218702 Common - hypothetical protein SCO0143 69 None None None 21220658 Common - transcriptional regulator SCO2184 60 COG2378 COG2378, Predicted transcriptional regulator Transcription 21225442 Common - oxidoreductase SCO7162 152 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21219236 Common - branched-chain amino acid transport ATP-binding protein SCO0710 235 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 21220930 Nonpathogen - hypothetical protein SCO2467 2 None None None 21221909 Common - lacI-family transcriptional regulator SCO3485 126 COG1609 PurR, Transcriptional regulators Transcription 21225840 Common - secreted hydrolase SCO7576 10 None None None 21218955 Nonpathogen - hypothetical protein SCO0413 1 None None None 21221766 Common - hydrolase SCO3336 70 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 21223464 Common - mini-circle protein SCO5093 10 None None None 21220644 Common - methyltransferase SCO2170 110 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 21223285 Common - bifunctional protein SCO4911 192 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21221157 Nonpathogen - secreted protein SCO2702 1 None None None 21221393 Common - hypothetical protein SCO2948 127 COG1678 COG1678, Putative transcriptional regulator Transcription 21222900 Nonpathogen - hypothetical protein SCO4515 2 None None None 21224347 Common - secreted chitinase (secreted protein) SCO6012 21 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 21219166 Common - hypothetical protein SCO0635 6 COG2267 PldB, Lysophospholipase Lipid metabolism 21220532 Common hisH imidazole glycerol phosphate synthase subunit HisH SCO2051 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 21223226 Common - tetR-family transcriptional regulator SCO4850 107 COG1309 AcrR, Transcriptional regulator Transcription 21220569 Common - putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase SCO2089 207 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 21219130 Common - hypothetical protein SCO0597 8 None None None 21223788 Common - integral membrane transport protein SCO5429 191 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21224071 Nonpathogen - hypothetical protein SCO5724 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 21218848 Common - oxidoreductase SCO0299 178 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21221833 Common - hypothetical protein SCO3406 181 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 21225117 Common - integral membrane protein SCO6825 157 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21225017 Common - oxidoreductase (secreted protein) SCO6723 29 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 21224353 Common - hypothetical protein SCO6021 20 None None None 21222077 Nonpathogen - hypothetical protein SCO3663 1 None None None 21224804 Common - gas vesicle synthesis protein SCO6501 14 None None None 21219844 Common - monooxygenase (secreted protein) SCO1338 70 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21225455 Common - secreted peptidase SCO7176 111 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21219306 Common - tetracycline resistance protein SCO0783 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 21224592 Common - secreted FAD-binding protein SCO6272 41 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21225333 Common - D-alanyl-D-alanine carboxypeptidase SCO7050 145 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 21220749 Common - TetR-family transcriptional regulator SCO2280 61 COG1309 AcrR, Transcriptional regulator Transcription 21218945 Common - hypothetical protein SCO0403 20 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21223417 Common - fumarate hydratase class I SCO5044 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 21220891 Common - regulatory protein SCO2426 9 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 21220356 Common - hypothetical protein SCO1868 35 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 21225650 Nonpathogen - hypothetical protein SCO7377 1 None None None 21223131 Common - O-sialoglycoprotein endopeptidase SCO4752 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 21224080 Nonpathogen - hypothetical protein SCO5733 1 None None None 21222895 Nonpathogen - hypothetical protein SCO4510 1 None None None 21223593 Common - ribonucleotide-diphosphate reductase small chain SCO5225 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 21224384 Common - hypothetical protein SCO6053 207 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 21224846 Nonpathogen - hypothetical protein SCO6544 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21218807 Common - hypothetical protein SCO0254 48 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21219849 Common - uracil-DNA glycosylase SCO1343 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 21224502 Nonpathogen - hypothetical protein SCO6177 1 None None None 32141141 Common - hypothetical protein SCO1381 20 COG0789 SoxR, Predicted transcriptional regulators Transcription 21223972 Nonpathogen - hypothetical protein SCO5617 1 None None None 21219331 Common - ABC transporter permease SCO0809 105 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 21219117 Common - cytochrome P450 SCO0584 59 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21224517 Common - transcriptional regulator SCO6193 55 COG3899 COG3899, Predicted ATPase General function prediction only 21222325 Common - lysR-family transcriptional regulator SCO3919 157 COG0583 LysR, Transcriptional regulator Transcription 21221432 Common - UDP-glucose 4-epimerase SCO2988 227 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 21223872 Common - integral membrane efflux protein SCO5516 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225272 Common - DNA-binding protein SCO6986 35 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21224361 Common - two-component regulator SCO6029 138 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219189 Common - DeoR-family transcriptional regulator SCO0659 113 COG1609 PurR, Transcriptional regulators Transcription 32141173 Common - 2-isopropylmalate synthase SCO2528 209 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 21219424 Nonpathogen - secreted protein SCO0904 1 None None None 21220430 Common tpiA triosephosphate isomerase SCO1945 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 21219782 Nonpathogen - hypothetical protein 2SCG1821 SCO1274 2 None None None 21220012 Nonpathogen - hypothetical protein SCO1512 1 None None None 21224259 Common - probable DEAD-box RNA helicase SCO5920 228 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 21224040 Common - hypothetical protein SCO5691 8 None None None 21220108 Common - short chain dehydrogenase SCO1611 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21220946 Nonpathogen - secreted protein SCO2483 1 None None None 21220621 Common - integral membrane transporter SCO2144 67 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 21221964 Common - transferase SCO3545 19 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 21221444 Common - hypothetical protein SCO3001 2 None None None 21225033 Common - BCCT family transporter SCO6739 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 21220102 Nonpathogen - hypothetical protein SCO1605 1 None None None 21219577 Common - hydrolase SCO1062 78 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21225359 Common - two-component histidine kinase SCO7076 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21221216 Common - lipoprotein SCO2764 17 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 21220755 Common - alkaline phosphatase SCO2286 57 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 21225216 Common - O-methyltransferase SCO6928 150 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 32141176 Nonpathogen - hypothetical protein SCO2616 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21223701 Nonpathogen - hypothetical protein SCO5340 1 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 21223362 Common - IclR-family transcriptional regulatory protein SCO4989 121 COG1414 IclR, Transcriptional regulator Transcription 21223745 Common - 3-hydroxybutyryl-coA dehydrogenase SCO5385 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21224125 Common - secreted protein SCO5780 89 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 21223617 Common - polyprenyl synthetase SCO5250 193 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 21225320 Common - secreted protein SCO7037 19 COG1572 COG1572, Uncharacterized conserved protein Function unknown 21221418 Common - serine/threonine protein kinase SCO2974 149 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21223544 Nonpathogen - integral membrane protein SCO5175 1 None None None 21225285 Common - hypothetical protein SCO6999 30 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 21219489 Common - lysR-family trancsriptional regulator SCO0971 186 COG0583 LysR, Transcriptional regulator Transcription 21223083 Common rplD 50S ribosomal protein L4 SCO4703 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 21218769 Common - hypothetical protein SCO0215 25 None None None 21225770 Common - extracellular solute-binding protein SCO7503 33 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21220004 Common - secreted protein SCO1503 11 None None None 21220742 Common - FecCD-family membrane transport protein SCO2273 187 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 21223808 Common - ABC transporter SCO5450 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21222189 Common - threonyl tRNA synthetase SCO3778 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21220296 Common - ABC transporter ATP-binding protein SCO1806 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21222795 Common - hypothetical protein SCO4406 8 None None None 21220524 Common - anthranilate synthase component I SCO2043 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 21224268 Common - oxidoreductase SCO5929 209 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21219210 Common - ferredoxin/ferredoxin-NADP reductase (putative secreted protein) SCO0681 187 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 21221125 Nonpathogen - hypothetical protein SCO2669 6 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 21221193 Nonpathogen - secreted protein SCO2741 1 None None None 21225898 Common - secreted endoglucanase SCO7637 28 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 21223845 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SCO5488 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 21223756 Common - cellulose-binding protein SCO5396 45 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 21222926 Common - hypothetical protein SCO4542 2 None None None 21223325 Common - tetR-family transcriptional regulator SCO4952 48 COG1309 AcrR, Transcriptional regulator Transcription 21220215 Nonpathogen - hypothetical protein SCO1721 1 None None None 21220733 Common - integral membrane protein SCO2264 80 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 32141304 Common - hypothetical protein SCO6492 13 None None None 21224085 Common - dihydrodipicolinate reductase SCO5739 214 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 21220179 Nonpathogen - hypothetical protein SCO1684 2 None None None 32141106 Common - sugar ABC-transporter integral membrane protein SCO0292 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21224681 Common - two-component sensor SCO6369 150 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21220839 Common aceE pyruvate dehydrogenase subunit E1 SCO2371 137 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 21223469 Nonpathogen - integral membrane protein SCO5098 1 None None None 21222584 Common - GntR-family transcriptional regulator SCO4188 54 COG2186 FadR, Transcriptional regulators Transcription 21221883 Common - integral membrane protein SCO3458 12 COG0398 COG0398, Uncharacterized conserved protein Function unknown 21225130 Common - monooxygenase SCO6838 171 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21218625 Common - hydrolase SCO0046 85 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 21218932 Common - lipoprotein SCO0389 6 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 21225673 Common - lyase SCO7402 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 21223293 Common - flavoprotein disulfide reductase SCO4919 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 21220493 Common - branched chain amino acid transport ATP-binding protein SCO2011 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 21222232 Common - hypothetical protein SCO3822 12 None None None 21223913 Common - hypothetical protein SCO5557a 11 COG1920 COG1920, Uncharacterized conserved protein Function unknown 21223516 Common - RNA polymerase sigma factor SigE SCO5147 175 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21223487 Common - peptide transport system secreted peptide-binding protein SCO5117 170 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 21222725 Nonpathogen - integral membrane protein SCO4333 2 None None None 21219976 Nonpathogen - hypothetical protein SCO1474 4 None None None 21218677 Common - tetR-family transcriptional regulator SCO0116 48 COG1309 AcrR, Transcriptional regulator Transcription 21223504 Common - hypothetical protein SCO5134 15 COG3393 COG3393, Predicted acetyltransferase General function prediction only 21219237 Common - hypothetical protein SCO0711 8 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21219652 Common - secreted protein SCO1138 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 21224295 Common - transport protein SCO5957 172 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219866 Common - hypothetical protein SCO1361 35 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21223412 Common - penicillin-binding protein SCO5039 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 21221033 Nonpathogen - hypothetical protein SCO2574 1 None None None 21221648 Common - probable anthranilate synthase component II SCO3213 237 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 21222228 Common - two-component system response transcriptional regulator SCO3818 194 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220697 Common - isomerase SCO2225 10 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 21218606 Nonpathogen - hypothetical protein SCO0027 1 None None None 21224866 Common - 3-oxoacyl-(acyl carrier protein) synthase III SCO6564 201 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 21220651 Common - cobalamin (5'-phosphate) synthase SCO2177 10 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 21223533 Common - hypothetical protein SCO5164 6 COG1432 COG1432, Uncharacterized conserved protein Function unknown 21224335 Common - aconitate hydratase SCO5999 222 COG1048 AcnA, Aconitase A Energy production and conversion 21224953 Common - hypothetical protein SCO6657 5 None None None 21218772 Common - nitrate reductase delta chain NarJ2 SCO0218 57 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 21225849 Common - merR-family transcriptional regulator SCO7585 34 COG0789 SoxR, Predicted transcriptional regulators Transcription 21221243 Common - araC-family transcriptional regulator SCO2792 134 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21222128 Common - ECF sigma factor SCO3715 43 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220134 Common - peptidyl-prolyl cis-trans isomerase SCO1638 147 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 21224297 Common - cobalt transport integral membrane protein SCO5959 44 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 32141323 Common - aldehyde dehydrogenase SCO7139 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21225691 Common - hypothetical protein SCO7421 10 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21221669 Common - oxygenase SCO3236 11 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 21220458 Common - hypothetical protein SCO1975 9 None None None 21221598 Common - ABC transport protein, ATP-binding subunit SCO3161 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 21225769 Common - LacI-family transcriptional regulator SCO7502 126 COG1609 PurR, Transcriptional regulators Transcription 21220571 Common - hypothetical protein SCO2091 7 None None None 21224303 Common - integral membrane protein SCO5965 6 None None None 21225991 Nonpathogen - hypothetical protein SCO7732 2 None None None 21225506 Common - membrane protein SCO7229 9 None None None 21223672 Common - hypothetical protein SCO5309 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 21219523 Nonpathogen - hypothetical protein SCO1006 1 None None None 21225594 Common - hypothetical protein SCO7318 8 COG1289 COG1289, Predicted membrane protein Function unknown 21221773 Common - hypothetical protein SCO3343 5 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 21219044 Common - hypothetical protein SCO0507 32 None None None 21219566 Common - DNA protection protein SCO1050 131 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 21219878 Common - hypothetical protein SCO1373 20 COG2170 COG2170, Uncharacterized conserved protein Function unknown 21225144 Nonpathogen - hypothetical protein SCO6853 1 None None None 21221810 Common - nicotinate-nucleotide pyrophosphorylase SCO3381 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 21222704 Common - hypothetical protein SCO4311 42 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21223365 Nonpathogen - hypothetical protein 2SCK3615 SCO4992 1 None None None 21221153 Nonpathogen - small hydrophilic protein SCO2698 1 None None None 21225352 Common - secreted hydrolase SCO7069 26 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 21221898 Common - sugar kinase SCO3474 164 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21222285 Common - 6-phosphogluconate dehydrogenase-like protein SCO3877 177 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 21225842 Nonpathogen - hypothetical protein SCO7578 1 None None None 21220978 Common - two-component system response regulator SCO2517 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21224956 Common - hypothetical protein SCO6660 19 COG3429 COG3429, Glucose-6-P dehydrogenase subunit Carbohydrate transport and metabolism 21219382 Nonpathogen - secreted protein SCO0861 1 None None None 21220451 Common - integral membrane protein SCO1967 38 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 21218968 Nonpathogen - hypothetical protein SCO0426 1 None None None 21223494 Nonpathogen - hypothetical protein SCO5124 4 None None None 21221515 Nonpathogen - integral membrane protein SCO3074 1 None None None 21225589 Nonpathogen - hypothetical protein SCO7313 1 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21221869 Common - pyridine nucleotide-disulphide oxidoreductase SCO3443 223 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 21224646 Common - hypothetical protein SCO6332 3 None None None 21224832 Common - hypothetical protein SCO6530 17 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 21222877 Common ubiA prenyltransferase SCO4491 161 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 21224967 Common - hypothetical protein SCO6671 11 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 21219713 Common - MutT-like protein SCO1203 20 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 21223305 Common - hypothetical protein SCO4931 171 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 21225329 Common ccrB camphor resistance protein CrcB SCO7046 6 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 21224962 Common - integral membrane protein SCO6666 37 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225437 Common - integral membrane protein SCO7157 63 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 21221652 Common - transcriptional regulator SCO3217 22 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21223689 Nonpathogen - hypothetical protein SCO5326 2 None None None 21224759 Common - transport permease protein SCO6453 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21219291 Common - hypothetical protein SCO0767 80 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21222353 Common - two component sensor SCO3948 99 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21224204 Nonpathogen - hypothetical protein SCO5861 1 None None None 21218877 Common - transcriptional regulator SCO0332 32 COG1309 AcrR, Transcriptional regulator Transcription 21218760 Common - luxR family two-component response regulator SCO0204 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225632 Nonpathogen - hypothetical protein SCO7358 13 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 21219793 Common - ketoreductase SCO1285 33 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21224896 Common - secreted protein SCO6596 21 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21219988 Common pyrB aspartate carbamoyltransferase catalytic subunit SCO1487 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 21221700 Nonpathogen - hypothetical protein SCO3267 1 None None None 21219294 Common - hypothetical protein SCO0771 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 21224390 Common - UDP-N-acetylmuramoyl-L-alanine ligase SCO6060 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 32141097 Common - transposase SCO0020 36 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 21221029 Nonpathogen - secreted protein SCO2570 1 None None None 21221028 Common - hypothetical protein SCO2569 48 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 21218855 Common - DNA-binding protein SCO0307 41 None None None 21221662 Common - glycolate oxidase SCO3228 109 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 21226079 Nonpathogen - hypothetical protein SCO7830 1 None None None 21220710 Common - membrane protein SCO2240 14 None None None 21225127 Common - arsenate reductase SCO6835 129 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 21219552 Common - phosphotriesterase-family protein SCO1036 31 COG1735 Php, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 32141331 Common - acetyltransferase (fragment) SCO7405 82 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 21220970 Common - undecaprenyl phosphate synthetase SCO2509 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 21221069 Common - rod shape-determining protein SCO2611 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 21219980 Common - guanylate kinase SCO1479 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 21223547 Common - molybdopterin biosynthesis-like protein MoeZ SCO5178 222 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 21222843 Common - integral membrane protein SCO4455 8 None None None 21218728 Common - nicotinate phosphoribosyltransferase SCO0171 108 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 21218694 Nonpathogen - hypothetical protein SCO0134 1 None None None 21219631 Common - secreted protein SCO1117 69 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 21220546 Common - hypothetical protein SCO2065 31 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 21226086 Nonpathogen - membrane protein SCO7837 1 None None None 21220046 Common - anthranilate synthase SCO1547 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 21223512 Common - DNA-3-methyladenine glycosylase I SCO5143 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 21219755 Common bioD dithiobiotin synthetase SCO1246 15 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 161353679 Common - citrate synthase 2 SCO4388 193 COG0372 GltA, Citrate synthase Energy production and conversion 21224717 Common - methionine aminopeptidase SCO6409 240 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 21225473 Common - polysaccharide biosynthesis protein SCO7194 150 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 21218670 Common - insertion element transposase SCO0106 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219371 Common - membrane protein SCO0850 7 None None None 21225943 Common - non-ribosomal peptide synthase SCO7683 207 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21222269 Common - serine/threonine protein kinase SCO3860 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21223680 Common - polyketide beta-ketoacyl synthase beta SCO5317 194 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21220702 Common - maltose permease SCO2230 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222697 Common - oxidoreductase SCO4304 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21219741 Common - urease accessory protein SCO1232 147 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 21219367 Common - hypothetical protein SCO0846 17 None None None 21225817 Common - oxidoreductase SCO7553 113 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21225661 Common - dehydrogenase SCO7388 52 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21222080 Common - regulatory protein SCO3666 18 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219499 Common - isocitrate lyase SCO0982 126 COG2224 AceA, Isocitrate lyase Energy production and conversion 21220019 Common - holliday junction DNA helicase SCO1519 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 21223550 Common - integral membrane protein SCO5181 13 COG0392 COG0392, Predicted integral membrane protein Function unknown 21225076 Common - hypothetical protein SCO6783 11 None None None 21221738 Common - hypothetical protein SCO3307 13 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21225860 Common - hypothetical protein SCO7597 6 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 21222827 Common - D-alanyl-D-alanine carboxypeptidase SCO4439 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 21222811 Common - hydrolase SCO4422 39 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21221609 Common - monooxygenase SCO3172 85 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21223446 Nonpathogen - dehydratase SCO5074 3 None None None 21220675 Common - heat shock protein HtpX SCO2202 190 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 21223066 Nonpathogen - hypothetical protein SCO4686 1 None None None 21220190 Nonpathogen - hypothetical protein SCO1695 1 None None None 21221208 Common - integral membrane protein SCO2756 96 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21218822 Common - binding-protein-dependent transport protein SCO0271 141 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222072 Nonpathogen - hypothetical protein SCO3657 1 None None None 21224840 Nonpathogen - integral membrane protein SCO6538 1 None None None 21220866 Common - hypothetical protein SCO2399 9 COG3393 COG3393, Predicted acetyltransferase General function prediction only 21225582 Common - regulatory protein SCO7306 19 None None None 21218684 Common - hypothetical protein SCO0124 43 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21223577 Common - tetR-family transcriptional regulator SCO5209 29 COG1309 AcrR, Transcriptional regulator Transcription 21220717 Nonpathogen - hypothetical protein SCO2247 1 None None None 21220302 Common - integral membrane transporter SCO1812 79 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 21220725 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase SCO2256 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 21220709 Common - NAD(+) synthase (glutamine-hydrolysing) SCO2238 208 COG0171 NadE, NAD synthase Coenzyme metabolism 21223143 Common - dehydrogenase SCO4764 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21221723 Common - regulatory protein SCO3291 7 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21222244 Common - dehydrogenase SCO3835 157 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21221568 Common - dehydratase SCO3130 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 21226020 Common - hypothetical protein SCO7766 63 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21219918 Nonpathogen - membrane protein SCO1415 1 None None None 21221801 Common - large ATP-binding protein SCO3372 21 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 21225381 Common - RNA polymerase sigma factor SCO7099 40 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21222851 Common - hydrolase SCO4464 122 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 21221558 Common - hypothetical protein SCO3119 46 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21222529 Nonpathogen - integral membrane protein SCO4130 1 None None None 21219731 Common - AsnC-family regulatory protein SCO1221 152 COG1522 Lrp, Transcriptional regulators Transcription 21220346 Common - hypothetical protein SCO1858 82 COG2138 COG2138, Uncharacterized conserved protein Function unknown 21226070 Nonpathogen - integral membrane protein SCO7821 1 None None None 21224539 Common - hypothetical protein SCO6216 36 COG0824 FcbC, Predicted thioesterase General function prediction only 21224247 Nonpathogen - hypothetical protein SCO5908 1 COG3905 COG3905, Predicted transcriptional regulator Transcription 21220502 Nonpathogen - hypothetical protein SCO2020 1 None None None 32141289 Common - hypothetical protein SCO6165 22 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 21219645 Common - hypothetical protein SCO1131 112 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 21222068 Common - two-component system regulator SCO3653 211 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21222686 Common - threonine synthase SCO4293 145 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 21221971 Nonpathogen - hypothetical protein SCO3552 1 None None None 21218756 Common - hypothetical protein SCO0200 32 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21219011 Common - araC family transcriptional regulator SCO0471 31 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21220400 Nonpathogen - small membrane protein SCO1913 1 None None None 21218909 Common - probable oxidoreductase (secreted protein) SCO0365 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21220886 Common - ABC-transporter integral membrane protein SCO2421 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 21221991 Common - hypothetical protein SCO3573 29 None None None 21223170 Common - two-component system DNA-binding response regulator SCO4792 178 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225762 Nonpathogen - hypothetical protein SCO7494 1 None None None 21222918 Nonpathogen - hypothetical protein SCO4534 2 None None None 21219349 Common - alkaline phosphatase SCO0828 57 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 21221875 Common - RNA polymerase sigma factor (ECF subfamily) SCO3450 112 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220234 Common - hypothetical protein SCO1740 8 COG1511 COG1511, Predicted membrane protein Function unknown 21223960 Nonpathogen - hypothetical protein SCO5605 1 None None None 21223057 Common - regulatory protein SCO4677 7 None None None 21220200 Common - alcohol dehydrogenase (zinc-binding) SCO1705 149 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 21219638 Common - integral membrane protein SCO1124 7 None None None 21218961 Common - zinc-binding oxidoreductase SCO0419 171 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21223662 Common - hypothetical protein SCO5299 16 None None None 21221586 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase SCO3148 125 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 21220844 Common - aldo/keto reductase SCO2377 194 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21220761 Common - secreted endo-1,4-beta-xylanase B (xylanase B) SCO2292 8 COG4907 COG4907, Predicted membrane protein Function unknown 21221781 Common - DNA-binding protein SCO3352 28 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 21220992 Common - PhoH-like protein SCO2532 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 21223732 Common - F0F1 ATP synthase subunit gamma SCO5372 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 21219195 Nonpathogen - secreted protein SCO0665 1 None None None 21225600 Common - anti-sigma factor antagonist SCO7325 38 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21219891 Common - membrane associated protein SCO1387 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 21222207 Common - hypothetical protein SCO3796 101 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21222446 Common - hypothetical protein SCO4043 13 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 21225539 Nonpathogen - hypothetical protein SCO7262 1 None None None 21222933 Common - hypothetical protein SCO4550 87 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 21223244 Common - methylmalonyl CoA mutase SCO4869 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 21222019 Common - potassium/proton antiporter SCO3603 82 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 21224499 Common - hypothetical protein SCO6174 111 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 21222175 Common - integral membrane protein SCO3764 207 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21222053 Common - two-component system regulator SCO3638 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219061 Common - oxidoreductase SCO0526 123 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225291 Common - oxidoreductase SCO7005 102 COG0579 COG0579, Predicted dehydrogenase General function prediction only 21223075 Common - hypothetical protein SCO4695 3 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21218643 Common - hydrolase (secreted protein) SCO0068 5 COG4833 COG4833, Predicted glycosyl hydrolase Carbohydrate transport and metabolism 21225733 Common - hypothetical protein SCO7464 9 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21221925 Common - binding protein dependent transport protein SCO3504 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21226059 Common - TetR-family transcriptional regulator SCO7809 6 COG1309 AcrR, Transcriptional regulator Transcription 21220246 Common - integral membrane protein SCO1753 7 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21220442 Common - fructokinase SCO1957 126 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21225869 Common - hydrolase SCO7607 127 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21220562 Common - cell division protein FtsZ SCO2082 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 21222872 Common - hypothetical protein SCO4486 17 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21224676 Common - two-component regulator SCO6363 200 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225087 Common - membrane protein SCO6794 10 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21224750 Common - gamma-glutamyl transferase SCO6444 146 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 21225054 Nonpathogen - hypothetical protein SCO6761 1 None None None 21224338 Nonpathogen - hypothetical protein SCO6002 1 None None None 21224816 Common - hypothetical protein SCO6513 9 None None None 21220903 Common - calcium-binding protein SCO2439 84 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 21225572 Common - hypothetical protein SCO7296 23 COG5207 UBP14, Isopeptidase T Posttranslational modification, protein turnover, chaperones 21223628 Common - malate oxidoreductase SCO5261 202 COG0281 SfcA, Malic enzyme Energy production and conversion 21222805 Common - monooxygenase SCO4416 105 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21225247 Common - hypothetical protein SCO6960 6 None None None 21221014 Common hrcA heat-inducible transcription repressor SCO2555 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 21224058 Nonpathogen - large Pro/Ala/Gly-rich protein SCO5710 1 COG5164 SPT5, Transcription elongation factor Transcription 21220245 Common - integral membrane protein SCO1752 10 COG5542 COG5542, Predicted integral membrane protein Function unknown 21223606 Common - TetR-family protein SCO5238 83 COG1309 AcrR, Transcriptional regulator Transcription 21221174 Common - long-chain fatty acid ligase SCO2720 209 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 21221305 Common - hypothetical protein SCO2855 2 None None None 21224423 Common - transport system integral membrane protein SCO6094 173 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 21219366 Common - hypothetical protein SCO0845 19 None None None 21221709 Common - integral membrane transporter SCO3276 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 21224948 Common - hypothetical protein SCO6652 9 None None None 21222533 Nonpathogen - lipoprotein SCO4135 1 None None None 21220539 Common - transcriptional regulatory protein SCO2058 108 COG2606 EbsC, Uncharacterized conserved protein Function unknown 21221224 Common - acyl CoA thioesterase II SCO2773 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 21219101 Common - insertion element transposase SCO0567 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21221491 Common - acyl-CoA hydrolase SCO3049 135 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 21225654 Nonpathogen - hypothetical protein SCO7381 1 None None None 21223190 Nonpathogen - integral membrane protein SCO4812 1 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 21219824 Common - hypothetical protein SCO1317 15 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 21221983 Common - sodium/proton antiporter SCO3564 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 21225167 Nonpathogen - hypothetical protein SCO6876 1 None None None 21223770 Nonpathogen - hypothetical protein SCO5410 1 None None None 21222156 Common - hypothetical protein SCO3744 8 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 21222482 Nonpathogen - hypothetical protein SCO4080 4 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 21222498 Common - ATP-dependent RNA helicase SCO4096 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 21219490 Common - transposase remnant SCO0972 5 None None None 21223194 Common - serine/threonine protein kinase SCO4817 123 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21220800 Common - hydrolase SCO2332 73 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225465 Nonpathogen - integral membrane protein SCO7186 1 None None None 32141240 Nonpathogen - hypothetical protein SCO4530 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 21223091 Common rpsQ 30S ribosomal protein S17 SCO4711 225 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 21225551 Nonpathogen - hypothetical protein SCO7274 1 None None None 21224279 Common - aminotransferase SCO5941 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 21219664 Common - integral membrane protein SCO1151 8 None None None 161353682 Common - DNA polymerase IV SCO1380 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 21224532 Common - DNA-binding protein SCO6208 9 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 21222736 Common - transposase SCO4344 24 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 21222049 Common - ABC transporter membrane-spanning protein SCO3634 19 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 21219956 Common - amino oxidase SCO1454 28 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 21221422 Common - secreted protein SCO2978 63 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21224439 Common - sugar kinase SCO6110 9 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 32141207 Common - transposase SCO3539 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21225749 Common - hypothetical protein SCO7481 11 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 21223377 Common - hypothetical protein SCO5004 2 None None None 21225447 Common - secreted sugar-binding protein SCO7167 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21222176 Common - integral membrane protein SCO3765 214 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21222638 Nonpathogen - secreted protein SCO4243 4 None None None 21223774 Common - hypothetical protein SCO5414 18 None None None 21225918 Nonpathogen - secreted protein SCO7657 4 None None None 21225399 Common - ferredoxin reductase SCO7117 222 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 21219608 Common - hydroxylase SCO1093 35 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21219262 Common - oxidoreductase SCO0737 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21226066 Common - DNA-binding protein SCO7817 40 None None None 21223934 Common - sugar transporter SCO5578 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224404 Nonpathogen - integral membrane protein SCO6074 2 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21221461 Common - regulatory protein SCO3018 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 21224488 Common - two-component system response regulator SCO6162 196 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220516 Common - hypothetical protein SCO2035 22 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 21219091 Common - MerR-family transcriptional regulator SCO0557 116 COG0789 SoxR, Predicted transcriptional regulators Transcription 21221018 Common - coproporphyrinogen III oxidase SCO2559 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 21220188 Nonpathogen - hypothetical protein SCO1693 1 None None None 21223402 Common - secreted protein SCO5029 16 None None None 21219312 Common - hypothetical protein SCO0789 69 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 21224585 Common - reductase SCO6264 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221466 Common - S-adenosyl-L-homocysteine hydrolase SCO3023 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 21222665 Nonpathogen - mutT-like protein SCO4272 6 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21221679 Common - 3-oxoacyl-(acyl carrier protein) synthase III SCO3246 204 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 21223347 Common - deaminase SCO4974 205 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 21223378 Common - hypothetical proten SCK1507 SCO5005 10 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 21224561 Common - hypothetical protein SCO6240 33 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21219889 Common - hypothetical protein SCO1385 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 21224912 Nonpathogen - hypothetical protein SCO6614 1 None None None 21222035 Common - hypothetical protein SCO3619 46 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 21224637 Common - integral membrane protein SCO6321 58 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21223690 Common - transposase SCO5327 6 None None None 21219692 Nonpathogen - hypothetical protein SCO1181 3 None None None 21223235 Nonpathogen - hypothetical protein SCO4859 1 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 21221295 Common - GntR-family transcriptional regulatory protein SCO2845 10 COG2188 PhnF, Transcriptional regulators Transcription 21224475 Common - ribosome-associated GTPase SCO6149 163 COG1162 COG1162, Predicted GTPases General function prediction only 21218592 Nonpathogen - hypothetical protein (secreted protein) SCO0010 1 None None None 21220284 Common - 3-methyladenine DNA glycosylase SCO1792 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 21221615 Common - molybdenum cofactor biosynthesis protein (putative secreted protein) SCO3179 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 21220607 Nonpathogen - hypothetical protein SCO2130 5 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 21218699 Common - merR-family transcriptional regulator SCO0140 17 COG0789 SoxR, Predicted transcriptional regulators Transcription 21222945 Common - NADH dehydrogenase subunit A SCO4562 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 21221445 Nonpathogen - hypothetical protein SCO3002 1 None None None 21223316 Common - oxidoreductase SCO4943 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21220310 Common moaA molybdenum cofactor biosynthesis protein A SCO1821 196 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 21221632 Common - 1-phosphofructokinase SCO3197 97 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 21219461 Common - RNA polymerase sigma factor SigL SCO0942 18 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21219110 Common - oxidoreductase SCO0576 11 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 21222557 Common - transcriptional regulatory protein SCO4159 202 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21218829 Common - glycosyl hydrolase SCO0279 33 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 21219319 Common - integral membrane protein SCO0797 2 None None None 31340553 Nonpathogen - integral membrane protein SCO1941 1 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 21220684 Nonpathogen - hypothetical protein SCO2212 1 None None None 21221365 Common - nicotinamidase SCO2918 123 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 21225494 Common - iron ABC transporter ATP-binding protein SCO7217 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 21220321 Nonpathogen - hypothetical protein SCO1832 1 None None None 21223693 Common - DNA methylase SCO5331 41 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 21222479 Common - phosphoribosylformylglycinamidine synthase subunit PurS SCO4077 106 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 21219342 Common - threonine dehydratase SCO0821 229 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 21218638 Common - glucokinase SCO0063 44 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21219037 Common - formyltransferase SCO0499 225 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 21219297 Common - cytochrome P450 SCO0774 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21222756 Nonpathogen - hypothetical protein SCO4365 1 None None None 21222135 Common - transcriptional regulator SCO3722 155 COG0640 ArsR, Predicted transcriptional regulators Transcription 21225484 Nonpathogen - membrane protein SCO7207 1 None None None 21225492 Common - hypothetical protein SCO7215 27 COG2320 GrpB, Uncharacterized conserved protein Function unknown 21225094 Common - LysR-family transcriptional regulator SCO6801 140 COG0583 LysR, Transcriptional regulator Transcription 21222516 Common - hypothetical protein SCO4117 25 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21226048 Nonpathogen - hypothetical protein SCO7796 1 None None None 21224375 Nonpathogen - integral membrane protein SCO6044 1 None None None 21221681 Common - 3-oxoacyl-[acyl carrier protein] synthase II SCO3248 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222558 Common - hydrolase SCO4160 31 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21220449 Common - export associated protein SCO1964 24 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21220264 Common - partitioning or sporulation protein SCO1772 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 21224699 Nonpathogen - hypothetical protein SCO6387 2 None None None 21225279 Common - regulatory protein SCO6993 17 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221332 Common - cytochrome P450 SCO2883 52 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21222396 Nonpathogen - hypothetical protein SCO3993 1 None None None 21225711 Common - transcriptional regulatory protein SCO7441 91 COG1309 AcrR, Transcriptional regulator Transcription 21221707 Common - hypothetical protein SCO3274 2 None None None 21225294 Common - ABC transporter ATP-binding protein SCO7008 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 32141226 Nonpathogen - secreted protein SCO4115 2 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 21223330 Nonpathogen - hypothetical protein SCO4957 2 None None None 21225027 Common - transcriptional regulator SCO6733 7 COG0789 SoxR, Predicted transcriptional regulators Transcription 21218885 Nonpathogen - hypothetical protein SCO0340 1 None None None 21219187 Nonpathogen - gas vesicle synthesis protein SCO0657 1 None None None 21225704 Nonpathogen - lipoprotein SCO7434 1 COG3212 COG3212, Predicted membrane protein Function unknown 21220402 Common - hypothetical protein SCO1915 11 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 21222549 Common - acetyltransferase SCO4151 32 COG0456 RimI, Acetyltransferases General function prediction only 21223310 Common - ABC transporter ATP-binding protein SCO4936 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21225607 Common - glycogen branching enzyme SCO7332 148 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 21222432 Common - hypothetical protein SCO4029 12 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 21220435 Common - hypothetical protein SCO1950 46 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 21222717 Common - cold shock protein B SCO4325 173 COG1278 CspC, Cold shock proteins Transcription 21223743 Common - ABC transporter, ATP-binding subunit SCO5383 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21224265 Common - hypothetical protein SCO5926 190 COG1048 AcnA, Aconitase A Energy production and conversion 21225347 Nonpathogen - secreted protein SCO7064 1 None None None 21225620 Common - probable ATP-dependent DNA ligase SCO7345 108 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 21218711 Common - hypothetical protein SCO0154 27 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 21225335 Nonpathogen - hypothetical protein SCO7052 1 None None None 21219612 Common - hydrolase SCO1097 162 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221543 Common - hypothetical protein SCO3104 93 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 21225705 Common - transmembrane transport protein SCO7435 99 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225895 Nonpathogen - hypothetical protein SCO7634 1 None None None 21223063 Common - glutamate dehydrogenase SCO4683 168 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 21219515 Common - Fe uptake system permease SCO0998 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 21223523 Common - hypothetical protein SCO5154 165 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 21220152 Common - hydrolase SCO1656 136 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 21222468 Nonpathogen - hypothetical protein SCO4066 1 COG4469 CoiA, Competence protein General function prediction only 21224999 Common - secreted protein SCO6705 14 None None None 21220286 Common - hypothetical protein SCO1795 94 COG1403 McrA, Restriction endonuclease Defense mechanisms 21219587 Nonpathogen - hypothetical protein SCO1072 1 None None None 21219993 Common - peptidase SCO1492 226 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 21221145 Common - membrane transport protein SCO2690 13 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224994 Common - protocatechuate 3,4-dioxygenase beta subunit SCO6700 51 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 21223339 Nonpathogen - hypothetical protein SCO4966 2 None None None 21225327 Common ccrB camphor resistance protein CrcB SCO7044 5 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 21219201 Nonpathogen - hypothetical protein SCO0671 1 None None None 21223722 Common - hypothetical protein SCO5362 234 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 21225695 Common - multidrug-efflux transporter protein SCO7425 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 32141284 Common - transmembrane transport protein SCO6054 159 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 21223172 Common - integral membrane protein SCO4794 10 None None None 32141168 Common - ABC-transporter integral membrane protein SCO2420 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 21221838 Common - membrane protein SCO3411 166 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21223669 Nonpathogen - protein phosphatase SCO5306 2 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 32141238 Common - serine/threonine protein kinase (fragment) SCO4481 137 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21225885 Common pntA NAD(P) transhydrogenase subunit alpha SCO7623 159 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 21222061 Common - oxidoreductase SCO3646 42 COG3483 TDO2, Tryptophan 2,3-dioxygenase (vermilion) Amino acid transport and metabolism 21223391 Nonpathogen - integral membrane protein SCO5018 1 None None None 21220550 Common - hypothetical protein SCO2070 54 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 21224716 Common - clp protease ATP binding subunit SCO6408 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 21225886 Common - tetR-family regulatory protein SCO7624 29 None None None 21222642 Common - hypothetical protein SCO4247 18 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 21221196 Nonpathogen - hypothetical protein SCO2744 1 None None None 21225684 Nonpathogen - integral membrane protein SCO7414 2 COG1295 Rbn, Predicted membrane protein Function unknown 21224134 Common - hypothetical protein SCO5789 4 None None None 21220171 Nonpathogen - small membrane protein SCO1675 1 None None None 21221142 Common ribA GTP cyclohydrolase II SCO2687 178 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 21222783 Common - hypothetical protein SCO4393 21 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 21223844 Common - hypothetical protein SCO5487 98 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 21221842 Common - esterase SCO3415 108 COG0657 Aes, Esterase/lipase Lipid metabolism 21220463 Common - hypothetical protein SCO1980 8 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21220518 Common - tryptophan synthase subunit beta SCO2037 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 21224556 Common - secreted beta-mannosidase SCO6234 12 None None None 21220622 Common - glycerate kinase SCO2145 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 21219816 Common - regulatory protein SCO1309 145 COG0640 ArsR, Predicted transcriptional regulators Transcription 21221711 Nonpathogen - hypothetical protein SCO3278 1 None None None 21225450 Common - secreted sugar hydrolase SCO7170 29 None None None 21225269 Common - hypothetical protein SCO6983 75 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 21221687 Nonpathogen - SpdC protein SCO3254 1 None None None 21222985 Common - NADH dehydrogenase subunit NuoH2 SCO4602 184 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 21221529 Common - ABC transporter ATP-binding protein SCO3089 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21224519 Common - acetyl-coenzyme A synthetase SCO6195 218 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 21221257 Common - mutase SCO2806 135 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21218976 Common - bifunctional maltose and glucose-specific PTS system components IICB SCO0434 53 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 21221046 Common - gamma-glutamyl kinase SCO2587 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 21224729 Common - two-component system regulatory protein SCO6422 190 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223785 Common - 6-phosphofructokinase SCO5426 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 21224316 Common - enoyl-CoA hydratase SCO5979 163 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21224322 Common - hypothetical protein SCO5985 32 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21225911 Common - secreted hydrolase SCO7650 37 None None None 21219502 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase SCO0985 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 21218594 Nonpathogen - hypothetical protein SCO0012 1 None None None 21221630 Nonpathogen - hypothetical protein SCO3195 1 None None None 21221534 Common - hypothetical protein SCO3095 17 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 21221181 Nonpathogen - hypothetical protein SCO2727 1 None None None 21223349 Common - hypothetical protein SCO4976 28 COG1656 COG1656, Uncharacterized conserved protein Function unknown 21220227 Common - acetyltransferase SCO1733 13 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 21225372 Common - integral membrane protein SCO7090 29 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225196 Common - hypothetical protein SCO6906 4 None None None 21224403 Common - cyclase SCO6073 12 None None None 21226081 Common - Na+/H+ antiporter SCO7832 103 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 21218989 Common - MarR-family regulatory protein SCO0447 18 COG1846 MarR, Transcriptional regulators Transcription 21224678 Common - ABC transporter ATP-binding protein SCO6366 246 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21218762 Common - pyruvate phosphate dikinase SCO0208 229 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 21225625 Common - AraC-family transcriptional regulator SCO7351 68 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21220960 Common - transport ATPase SCO2499 194 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 21219958 Nonpathogen - hypothetical protein SCO1456 1 None None None 21223156 Common - protein serine/threonine kinase SCO4777 152 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21225836 Common - oxidoreductase SCO7572 196 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21221052 Common - hypothetical protein SCO2594 20 None None None 21223695 Nonpathogen - hypothetical protein SCO5334 1 None None None 21225432 Nonpathogen - hypothetical protein SCO7152 1 None None None 21222598 Common - NLP/P60-family secreted protein SCO4202 120 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21225195 Nonpathogen - hypothetical protein SCO6905 1 None None None 21222847 Nonpathogen - hypothetical protein SCO4460 4 None None None 21219694 Common - hypothetical protein SCO1183 59 COG0714 COG0714, MoxR-like ATPases General function prediction only 21225002 Nonpathogen - hypothetical protein SCO6708 1 None None None 21219330 Common - secreted solute-binding lipoprotein SCO0808 87 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21224973 Common - ABC transporter ATP-binding protein SCO6677 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 21219679 Nonpathogen - integral membrane protein SCO1166 1 None None None 21223797 Common - thioredoxin SCO5438 229 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 21222658 Common - transport integral membrane protein SCO4265 176 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21219347 Common - hypothetical protein SCO0826 9 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21222142 Common - oxidoreductase SCO3730 131 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21220922 Common - hypothetical protein SCO2458 7 None None None 21222422 Common - gntR family regulatory protein SCO4019 55 COG1802 GntR, Transcriptional regulators Transcription 21224173 Common - two-component sensor SCO5829 165 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 21222548 Nonpathogen - ABC transport system transmembrane protein SCO4150 1 None None None 21221503 Common - two-component system histidine kinase SCO3062 209 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21224016 Common - hypothetical protein SCO5665 14 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 21218721 Common - cation-transporting ATPase SCO0164 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 21223855 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A SCO5499 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 21218718 Nonpathogen - hypothetical protein SCO0161 1 None None None 21220544 Nonpathogen - small hydrophilic protein SCO2063 1 None None None 21220198 Common - transcriptional regulator SCO1703 37 COG0640 ArsR, Predicted transcriptional regulators Transcription 21221353 Common - PTS transmembrane component SCO2906 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 21219548 Common - ABC transport system ATP-binding protein SCO1032 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21220374 Common - integral membrane transport protein SCO1887 172 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222200 Common - integral membrane protein SCO3789 26 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 21220039 Common - lipoprotein SCO1539 58 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219551 Common - hypothetical protein SCO1035 13 None None None 21223340 Common - hypothetical protein SCO4967 34 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 21225312 Common - probable LacI-family transcriptional regulator SCO7027 126 COG1609 PurR, Transcriptional regulators Transcription 21223992 Common - transposase SCO5641 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21224504 Common - nucleotide-sugar dehydratase SCO6179 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223671 Common - hypothetical protein SCO5308 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 21219766 Common - ABC transport system ATP-binding protein SCO1258 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21222317 Common - hypothetical protein SCO3910 170 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 21224066 Nonpathogen - hypothetical protein SCO5719 3 None None None 21221502 Common - integral membrane protein SCO3061 16 COG2246 COG2246, Predicted membrane protein Function unknown 21219352 Nonpathogen - hypothetical protein SCO0831 2 None None None 21219930 Nonpathogen - hypothetical protein SCO1427 1 None None None 21223280 Common - sensor kinase protein SCO4906 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21224342 Common - probable transmembrane transport protein SCO6007 156 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21223946 Common rpsP 30S ribosomal protein S16 SCO5591 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 21225977 Nonpathogen - hypothetical protein SCO7718 1 None None None 21222869 Common - hypothetical protein SCO4483 30 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21225223 Nonpathogen - hypothetical protein SCO6936 1 None None None 21219088 Nonpathogen - hypothetical protein SCO0553 1 None None None 21225404 Common - acetyltransferase SCO7122 16 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 21226090 Common - ATP/GTP-binding protein SCO0006 5 None None None 21223764 Common - probable two-component sensor kinase SCO5404 129 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21225556 Nonpathogen - DNA-binding protein SCO7279 2 COG1396 HipB, Predicted transcriptional regulators Transcription 21224856 Common - transcriptional regulatory protein SCO6554 44 COG1522 Lrp, Transcriptional regulators Transcription 21223134 Common - transcriptional regulator SCO4755 60 COG1316 LytR, Transcriptional regulator Transcription 21223038 Common - integral membrane protein SCO4657 19 COG5542 COG5542, Predicted integral membrane protein Function unknown 21225045 Common - efflux protein SCO6751 191 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 21223060 Common - DNA-binding protein SCO4680 41 COG1396 HipB, Predicted transcriptional regulators Transcription 32141191 Common - oxidoreductase SCO3092 171 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 21221117 Common - sugar hydrolase SCO2661 50 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 21221496 Common - hypothetical protein SCO3054 12 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21222472 Common - hypothetical protein SCO4070 22 None None None 21218682 Common - flavin-containing monooxygenase (putative secreted protein) SCO0122 89 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21223711 Nonpathogen - hypothetical protein SCO5350 1 None None None 21222591 Common - ATP/GTP binding protein SCO4195 34 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 21220810 Common - secreted protein SCO2342 7 None None None 21223932 Common - acylphosphatase SCO5576 92 COG1254 AcyP, Acylphosphatases Energy production and conversion 21220056 Common - lipoprotein SCO1557 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 21219674 Common - integral membrane protein SCO1161 42 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 21219705 Common - export protein SCO1194 168 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21223205 Common - betaine aldehyde dehydrogenase SCO4828 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21225618 Common - porphobilinogen deaminase SCO7343 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 21224613 Common - gntR-family regulatory protein SCO6294 125 COG1802 GntR, Transcriptional regulators Transcription 21221932 Common - lipoprotein SCO3511 111 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21222695 Nonpathogen - secreted protein SCO4302 1 None None None 21224611 Common - dihydropicolinate synthase SCO6292 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 21221434 Common - hypothetical protein SCO2990 12 None None None 21224635 Common - lipoprotein SCO6319 9 None None None 21225923 Common - chloramphenicol resistance protein SCO7662 100 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219442 Common sdhA succinate dehydrogenase flavoprotein subunit SCO0923 225 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 21226088 Nonpathogen - hypothetical protein SCO7839 1 None None None 21224745 Common - DNA-binding protein SCO6439 91 COG1278 CspC, Cold shock proteins Transcription 21224819 Common - uvrA-like protein SCO6517 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 21223952 Common - signal peptidase I SCO5597 164 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 21224580 Common - probable ABC sugar transport ATP binding protein SCO6259 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 21221385 Nonpathogen - hypothetical protein SCO2939 1 None None None 21221886 Nonpathogen - integral membrane protein SCO3461 2 None None None 21221313 Common - helicase SCO2863 213 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 21223983 Common - integral membrane protein SCO5628 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 21219006 Common - araC family transcriptional regulator SCO0466 123 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21221803 Nonpathogen - hypothetical proline-rich protein SCO3374 1 None None None 32141295 Common - type I polyketide synthase SCO6275 211 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21219431 Common - hypothetical protein SCO0911 112 COG1262 COG1262, Uncharacterized conserved protein Function unknown 21224242 Common - RNA methyltransferase SCO5901 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 21218903 Common - hypothetical protein SCO0359 21 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 21221109 Common - hypothetical protein SCO2652 56 COG1959 COG1959, Predicted transcriptional regulator Transcription 21221287 Common - secreted protein SCO2837 15 None None None 21222777 Common - pyridoxamine oxidase SCO4387 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 21224216 Common - hypothetical protein SCO5873 11 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 21218788 Common - short chain dehydrogenase SCO0235 68 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21220035 Common - hypothetical protein SCO1535 10 None None None 21219787 Common - secreted protein SCO1279 18 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21220354 Common ectC L-ectoine synthase SCO1866 35 None None None 21222295 Common - hypothetical protein SCO3888 11 None None None 21226013 Common - DNA-binding protein SCO7759 86 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225147 Nonpathogen - hypothetical protein SCO6856 1 None None None 21224155 Common - transmembrane efflux protein SCO5810 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219392 Common - two-component sensor protein SCO0871 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 21222037 Common - serine-threonine protein kinase SCO3621 141 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21221274 Common - NAD-binding protein SCO2824 225 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 21222417 Common - hypothetical protein SCO4014 134 COG1733 COG1733, Predicted transcriptional regulators Transcription 21222279 Common - decarboxylase SCO3871 77 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 21220474 Nonpathogen - integral membrane protein SCO1992 2 None None None 21223588 Nonpathogen - hypothetical protein SCO5220 3 None None None 21225300 Common - secreted glycosyl hydrolase SCO7015 63 COG1572 COG1572, Uncharacterized conserved protein Function unknown 21220251 Common engA GTP-binding protein EngA SCO1758 217 COG1160 COG1160, Predicted GTPases General function prediction only 21225242 Nonpathogen - putative monovalent cation/H+ antiporter subunit C SCO6955 1 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 21220425 Common - 6-phosphogluconolactonase SCO1939 101 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 21223686 Common - Asn-C family transcriptional regulator SCO5323 91 COG1522 Lrp, Transcriptional regulators Transcription 21219327 Common - prolyl aminopeptidase SCO0805 29 COG2267 PldB, Lysophospholipase Lipid metabolism 21222607 Common - integrase, partial CDS SCO4211 82 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 21224859 Common - neuramidase (secreted protein) SCO6557 16 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 21225782 Common - heat shock protein 90 SCO7516 147 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 31340545 Common - expression regulator SCO1748 5 None None None 32141245 Common - adenylate kinase SCO4723 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 21224936 Common - ATP/GTP binding protein SCO6639 28 None None None 21223652 Common - secreted hydrolase SCO5286 42 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 21220680 Common - carboxylesterase SCO2208 18 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 32141127 Common - regulatory protein SCO0946 107 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21219180 Common - gas vesicle synthesis-like protein SCO0650 22 None None None 21224623 Common - hypothetical protein SCO6305 47 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 21224116 Common recX recombination regulator RecX SCO5770 16 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 21222995 Common - amino acid transporter SCO4612 36 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21224733 Common - hypothetical protein SCO6426 126 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 21221959 Common - proteinase (secreted protein) SCO3540 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21218734 Nonpathogen - membrane protein SCJ126 SCO0177 1 None None None 21219857 Common - large transcriptional regulator SCO1351 28 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223636 Nonpathogen - hypothetical protein 2SC7G1131 SCO5269 1 None None None 21219433 Common - lipoprotein SCO0914 88 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21218675 Common - oxidoreductase SCO0111 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21222164 Common - ABC transporter ATP-binding protein SCO3752 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21220057 Common - ABC transporter permease protein SCO1558 102 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 21221694 Common - ATP-binding protein SCO3261 24 COG3950 COG3950, Predicted ATP-binding protein involved in virulence General function prediction only 21222972 Common - aminopeptidase (secreted protein) SCO4589 57 COG2234 Iap, Predicted aminopeptidases General function prediction only 21219807 Common - exonuclease SCO1300 87 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 21222832 Common - glutathione peroxidase SCO4444 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 21220165 Common - ATP/GTP-binding protein SCO1669 86 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21222300 Common - hypothetical protein SCO3893 21 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21219057 Common - oxidoreductase SCO0522 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21224443 Common - hypothetical protein SCO6116 31 COG5476 COG5476, Uncharacterized conserved protein Function unknown 21225230 Common - sensor histidine-kinase SCO6943 18 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 21219475 Common - oxidoreductase SCO0957 24 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21224576 Common - dehydrogenase SCO6255 138 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21220453 Common - DNA-methyltransferase SCO1969 31 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 21221524 Common - integral membrane protein SCO3083 26 COG4760 COG4760, Predicted membrane protein Function unknown 21223958 Common - hypothetical protein SCO5603 196 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 21222774 Common - enoyl-CoA hydratase SCO4384 142 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21219791 Common - hypothetical protein SCO1283 5 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 21222050 Nonpathogen - hypothetical protein SCO3635 1 None None None 21223595 Nonpathogen - redoxin SCO5227 1 None None None 21222667 Common - secreted protein SCO4274 20 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 21226041 Nonpathogen - secreted oxidoreductase SCO7790 1 None None None 21224424 Common - ABC transporter ATP-binding protein SCO6095 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 21225949 Common - ABC transporter ATP-binding protein SCO7689 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21220786 Common - glycosyl transferase SCO2318 94 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21225158 Nonpathogen - hypothetical protein SCO6867 1 None None None 21218631 Nonpathogen - hypothetical protein SCO0056 1 None None None 21225822 Common - beta-glucosidase SCO7558 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 21219800 Common - hypothetical protein SCO1293 28 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 21220365 Nonpathogen - hypothetical protein SCO1877 1 None None None 21218800 Common - hypothetical protein SCO0247 20 COG4326 Spo0M, Sporulation control protein General function prediction only 21220796 Common - dipeptidase SCO2328 28 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 21224606 Common - thioesterase II SCO6287 47 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21225520 Common - secreted protein SCO7243 145 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21225775 Common - hypothetical protein SCO7508 45 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 21224989 Nonpathogen - hypothetical protein SCO6695 1 None None None 21220363 Common - secreted penicillin binding protein SCO1875 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21222562 Common - hypothetical protein SCO4165 10 None None None 21219216 Common - probable oxidoreductase SCO0687 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21223307 Nonpathogen - hypothetical protein SCO4933 1 None None None 21218696 Common ulaA ascorbate-specific PTS system enzyme IIC SCO0136 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 21219730 Common - regulatory protein SCO1220 130 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 21223263 Common - cytidine deaminase SCO4889 114 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 21221175 Common - lipoprotein SCO2721 62 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 21222391 Nonpathogen - hypothetical protein SCO3987 1 None None None 21223129 Common - hypothetical protein SCO4750 181 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 21220060 Common - integral membrane protein SCO1561 2 None None None 21222410 Common - integral membrane protein SCO4007 62 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224852 Common - oxidoreductase SCO6550 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 32141136 Common - bifunctional protein SCO1226 42 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 21220981 Nonpathogen - hypothetical protein SCO2520 2 None None None 21224306 Common - hypothetical protein SCO5969 34 COG1694 MazG, Predicted pyrophosphatase General function prediction only 21224460 Common - hypothetical protein SCO6133 15 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 21219124 Common - lysozyme precursor SCO0591 43 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 21224707 Nonpathogen - hypothetical protein SCO6399 3 None None None 21220557 Common - hypothetical protein SCO2077 20 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 21224843 Nonpathogen - hypothetical protein SCO6541 2 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21223151 Common - transposase SCO4772 45 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 21224941 Common - solute-binding lipoprotein SCO6644 86 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21225907 Nonpathogen - hypothetical protein SCO7646 1 None None None 21219962 Nonpathogen - hypothetical protein SCO1460 1 None None None 21220774 Common - ABC transporter ATP-binding subunit SCO2305 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21224825 Common - hypothetical protein SCO6523 111 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 21223478 Common sdhA succinate dehydrogenase flavoprotein subunit SCO5107 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 21225365 Nonpathogen - insertion element transposase (fragment) SCO7083 1 None None None 21224207 Common - hypothetical protein SCO5864 19 None None None 21222114 Common - hypothetical protein SCO3701 4 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 21224317 Common - salicylyl-CoA 5-hydroxylase SCO5980 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 21218667 Common - flavohemoprotein SCO0103 141 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 21224387 Common - ATP/GTP-binding integral membrane protein SCO6057 91 COG1485 COG1485, Predicted ATPase General function prediction only 21221796 Common - tetR-family regulator SCO3367 130 COG1309 AcrR, Transcriptional regulator Transcription 21221480 Common - F420-0--gamma-glutamyl ligase SCO3037 51 COG1478 COG1478, Uncharacterized conserved protein Function unknown 21221341 Common - ABC-transport protein, ATP-binding component SCO2894 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 21222230 Common - serine/threonine protein kinase SCO3820 153 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21221937 Nonpathogen - hypothetical protein SCO3516 1 None None None 21222997 Common - nucleotide-binding protein SCO4614 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 21222108 Nonpathogen - secreted protein SCO3695 16 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21222198 Nonpathogen - integral membrane protein SCO3787 2 None None None 21221746 Common - transcriptional regulator SCO3315 19 COG1309 AcrR, Transcriptional regulator Transcription 21221401 Common - integral-membrane protein SCO2956 2 COG5500 COG5500, Predicted integral membrane protein Function unknown 21225258 Common - precorrin 6A synthase SCO6971 52 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 21223818 Common - AbaA-like regulatory protein SCO5460 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21219028 Common - esterase SCO0490 17 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 21224765 Common - regulatory protein SCO6459 18 COG0640 ArsR, Predicted transcriptional regulators Transcription 21224140 Common - zinc metalloprotease (membrane protein) SCO5795 146 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 21225710 Common - hydrolase SCO7440 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225423 Common - transcriptional regulator SCO7143 44 COG3899 COG3899, Predicted ATPase General function prediction only 21225940 Common - ABC transporter ATP-binding protein SCO7680 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 21225717 Common - hypothetical protein SCO7448 97 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221817 Common - two component system response regulator SCO3389 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21218838 Nonpathogen - hypothetical protein SCO0288 1 None None None 21222578 Common - hypothetical protein SCO4181 75 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 21221808 Nonpathogen - hypothetical protein SCO3379 1 None None None 21225966 Common - hypothetical protein SCO7707 9 None None None 21222005 Common - hypothetical protein SCO3588 17 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 21220069 Common - hypothetical protein SCO1571 24 None None None 21223981 Common pyrH uridylate kinase SCO5626 237 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 21223018 Common - hypothetical protein SCO4636 32 COG2030 MaoC, Acyl dehydratase Lipid metabolism 21222355 Common - hypothetical protein SCO3950 108 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 21222914 Nonpathogen - integral membrane protein SCO4529 1 None None None 21219590 Common - bifunctional protein (ATP/GTP binding protein/MutT-like) SCO1075 35 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21221269 Nonpathogen - hypothetical protein SCO2819 1 None None None 21223835 Common - oligopeptide transport system integral membrane protein SCO5478 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21222886 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SCO4501 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21225987 Common - hypothetical protein SCO7728 23 COG2388 COG2388, Predicted acetyltransferase General function prediction only 21226000 Common - bifunctional protein SCO7741 66 COG0431 COG0431, Predicted flavoprotein General function prediction only 21218663 Nonpathogen - integral membrane protein SCO0097 1 None None None 21220957 Common - pyruvate phosphate dikinase SCO2494 232 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 21223575 Common - hypothetical protein SCO5207 114 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 21224448 Common - transcriptional regulator SCO6121 73 COG1309 AcrR, Transcriptional regulator Transcription 21224563 Common - hypothetical protein SCO6242 17 None None None 21224103 Nonpathogen - hypothetical protein SCO5757 1 None None None 21223754 Common - ABC transporter integral membrane subunit SCO5394 16 None None None 32141156 Common - oxidoreductase SCO2107 105 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 21225613 Common - glycogen debranching enzyme SCO7338 159 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 21220583 Common - 5,10-methylenetetrahydrofolate reductase SCO2103 154 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 21219626 Common - oxidoreductase SCO1112 135 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21220167 Common - hypothetical protein SCO1671 49 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 21223621 Nonpathogen - superoxide dismutase SCO5254 13 None None None 21225177 Common - hypothetical protein SCO6886 5 None None None 21223210 Common - hypothetical protein SCO4834 79 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21219601 Common - hypothetical protein SCO1086 19 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 21221587 Common ksgA dimethyladenosine transferase SCO3149 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 21224778 Common - transcriptional regulator SCO6474 64 COG1309 AcrR, Transcriptional regulator Transcription 21224809 Common - gas vesicle protein SCO6506 12 None None None 32141202 Common - hypothetical protein SCO3394 18 COG3428 COG3428, Predicted membrane protein Function unknown 21220048 Nonpathogen - hypothetical protein SCO1549 3 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 21220385 Common - substrate binding protein SCO1898 92 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21223924 Common - phosphopantetheine adenylyltransferase SCO5568 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 21221100 Common - aminopeptidase N SCO2643 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 21220787 Common - tetR-family regulatory protein SCO2319 18 COG1309 AcrR, Transcriptional regulator Transcription 21221237 Common - beta-N-acetylhexosaminidase SCO2786 54 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 21225340 Common - esterase SCO7057 19 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 21219383 Common - integral membrane protein SCO0862 3 None None None 21225522 Common - hydrolase SCO7245 71 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21224548 Common - hypothetical protein SCO6226 19 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 21219137 Common - hypothetical protein SCO0604 7 None None None 21221162 Common - transferase SCO2707 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 21224254 Common - hypothetical protein SCO5915 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21225183 Nonpathogen - hypothetical protein SCO6892 1 None None None 21219402 Common - hypothetical protein SCO0882 6 COG4700 COG4700, Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats Function unknown 21224951 Common - GTP cyclohydrolase II SCO6655 205 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 21225750 Nonpathogen - integral membrane protein SCO7482 1 COG2246 COG2246, Predicted membrane protein Function unknown 32141181 Common - agmatinase SCO2770 159 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 21219155 Common - membrane transport protein SCO0623 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221626 Nonpathogen - hypothetical protein SCO3191 1 None None None 21218943 Common - epimerase SCO0400 164 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 21219501 Common - 3-hydroxybutyryl-CoA dehydrogenase SCO0984 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21223907 Common - regulator SCO5552 91 COG1414 IclR, Transcriptional regulator Transcription 21218818 Common - hydrolase SCO0267 164 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21220333 Common - aldolase SCO1844 132 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 21224180 Common - DNA topoisomerase IV subunit A SCO5836 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 21221918 Common - lyase precursor SCO3496 7 None None None 21224026 Common - 4-aminobutyrate aminotransferase SCO5676 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 21223090 Common - 50S ribosomal protein L29 SCO4710 80 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 21224414 Common - hypothetical protein SCO6085 5 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 21220747 Nonpathogen - hypothetical protein SCO2278 1 None None None 21221751 Common - redox-sensing transcriptional repressor Rex SCO3320 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 21222677 Common - N-acetylglucosamine-6-phosphate deacetylase SCO4284 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 21220695 Common - tetR-family transcriptional regulator SCO2223 23 COG1309 AcrR, Transcriptional regulator Transcription 21221416 Nonpathogen - secreted protein SCO2971 1 None None None 21220273 Common ppnK inorganic polyphosphate/ATP-NAD kinase SCO1781 235 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 21222836 Nonpathogen - hypothetical protein SCO4448 4 None None None 21221292 Nonpathogen - membrane protein SCO2842 1 None None None 21225809 Common - ABC-transport protein, membrane component SCO7544 198 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 21221248 Common - cellobiose transport permease SCO2797 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21224907 Common - secreted protein SCO6609 37 COG0627 COG0627, Predicted esterase General function prediction only 21219067 Common - sugar transporter membrane protein SCO0532 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222797 Nonpathogen - hypothetical protein SCO4408 2 None None None 21219070 Common - hydrolase (secreted protein) SCO0535 9 None None None 21224684 Nonpathogen - very hypotheticl protein SC4A208 SCO6372 1 None None None 21223806 Common - ABC transporter SCO5448 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21220564 Common murG N-acetylglucosaminyl transferase SCO2084 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 21221946 Nonpathogen - hypothetical protein SCO3525 1 None None None 21222121 Nonpathogen - integral membrane protein SCO3708 1 None None None 21220827 Common - two-component system sensor kinase SCO2359 133 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21222091 Common dcd deoxycytidine triphosphate deaminase SCO3678 161 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 21222097 Common - hypothetical protein SCO3684 4 None None None 21224771 Common - phosphatidylserine synthase SCO6467 95 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 21220591 Common - bacterioferritin SCO2113 109 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 21219868 Common - integral membrane protein SCO1363 13 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 21222755 Common - hypothetical protein SCO4364 13 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 21221647 Common - probable anthranilate phosphoribotransferase SCO3212 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 32141109 Common - integral membrane transport protein SCO0375 148 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 32141216 Common - acyl-CoA dehydrogenase SCO3800 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21225935 Nonpathogen - integral membrane protein SCO7675 1 None None None 21223356 Nonpathogen - hypothetical protein 2SCK3606c SCO4983 1 None None None 21219978 Common - S-adenosylmethionine synthetase SCO1476 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 21220300 Nonpathogen - hypothetical protein SCO1810 1 None None None 21223910 Nonpathogen - hypothetical protein SCO5555 1 None None None 21224792 Common - acyl-peptide hydrolase SCO6488 94 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21223006 Nonpathogen - hypothetical protein SCO4623 1 None None None 21222711 Nonpathogen - integral membrane protein SCO4319 1 None None None 21220652 Common - endo alpha-1,4 polygalactosaminidase SCO2178 19 COG3868 COG3868, Uncharacterized conserved protein Function unknown 21224379 Nonpathogen - integral membrane protein SCO6048 1 None None None 21225233 Nonpathogen - hypothetical protein SCO6946 1 None None None 21225768 Common - hydrolase SCO7501 21 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 21219721 Common - polypeptide deformylase SCO1211 210 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 21225512 Common - integral membrane protein SCO7235 16 None None None 32141315 Common - hypothetical protein SCO6849 20 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 21220145 Nonpathogen - ferredoxin SCO1649 4 COG1141 Fer, Ferredoxin Energy production and conversion 21220319 Common - hypothetical protein SCO1830 70 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 21220399 Common - dihydrodipicolinate synthase SCO1912 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 21221136 Common - ATP /GTP-binding protein SCO2681 42 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 21221878 Common - ABC-transporter ATP binding protein SCO3453 248 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 21220089 Common - hypothetical protein SCO1592 7 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21219126 Nonpathogen - hypothetical protein SCO0593 1 None None None 21222374 Common - Xaa-Pro aminopeptidase SCO3970 223 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 21223253 Common - hypothetical protein SCO4879 4 None None None 21220526 Common - hypothetical protein SCO2045 15 None None None 21222979 Common - two-component system response regulator SCO4596 176 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219929 Nonpathogen - hypothetical protein SCO1426 1 None None None 21223106 Common rpsM 30S ribosomal protein S13 SCO4727 247 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 21222185 Common - beta-lactamase related protein SCO3774 21 COG2367 PenP, Beta-lactamase class A Defense mechanisms 21218640 Common - extracellular binding protein SCO0065 69 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21221241 Common - hypothetical protein SCO2790 18 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21222605 Common - phosphoglyceromutase SCO4209 151 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 21222624 Common - sensor kinase SCO4229 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 21221509 Common - RNA polymerase sigma factor SCO3068 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21221690 Common - plasmid transfer protein SCO3257 13 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21219256 Common - transferase SCO0731 95 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 21219380 Common - membrane protein SCO0859 5 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 21219986 Common - integral membrane protein SCO1485 10 None None None 21220006 Common rpsD 30S ribosomal protein S4 SCO1505 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 21220994 Common - hypothetical protein SCO2535 37 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 21219708 Common - acyl-CoA dehydrogenase SCO1197 24 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21223200 Nonpathogen - hypothetical protein SCO4823 1 None None None 21223623 Common - hypothetical protein SCO5256 12 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21219950 Common - transport protein SCO1448 63 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21222182 Common - secreted penicillin binding protein SCO3771 133 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21220497 Common - nucleotidase SCO2015 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 21223880 Common - bifunctional urease subunit gamma/beta SCO5525 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 21219647 Common - oxidoreductase, molybdopterin binding subunit SCO1133 85 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 21225546 Common - hypothetical protein SCO7269 13 None None None 21223291 Common - purine nucleoside phosphorylase SCO4917 151 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 21221031 Nonpathogen - integral membrane protein SCO2572 4 COG2717 COG2717, Predicted membrane protein Function unknown 21218984 Common - hypothetical protein SCO0442 95 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 21224098 Common - hypothetical protein SCO5752 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 21218854 Common - hypothetical protein SCO0305 28 COG2319 COG2319, FOG: WD40 repeat General function prediction only 21222525 Common - hypothetical protein SCO4126 7 None None None 21221624 Nonpathogen - hypothetical protein SCO3189 1 None None None 21219603 Common - oxidoreductase SCO1088 4 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221283 Common - secreted chitin binding protein SCO2833 27 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 21219662 Common - hypothetical protein SCO1149 5 None None None 21221904 Common - racemase SCO3480 134 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 32141325 Nonpathogen - regulatory protein SCO7198 1 None None None 21220720 Nonpathogen - hypothetical protein SCO2250 4 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21220471 Common - aminopeptidase SCO1989 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225428 Nonpathogen - hypothetical protein SCO7148 1 None None None 21223029 Common - transcription antitermination protein SCO4647 215 COG0250 NusG, Transcription antiterminator Transcription 21219042 Common - DEAD-box RNA-helicase SCO0504 220 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 21223604 Common nagB glucosamine-6-phosphate deaminase SCO5236 97 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 21220656 Common - gntR-family transcriptional regulator SCO2182 47 COG1802 GntR, Transcriptional regulators Transcription 21218627 Nonpathogen - hypothetical protein SCO0048 1 None None None 21219161 Common - transcriptional regulator SCO0629 107 COG1609 PurR, Transcriptional regulators Transcription 21220126 Common - integral membrane protein SCO1630 21 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21222582 Common - hypothetical protein SCO4185 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 21223233 Common - succinate dehydrogenase membrane subunit SCO4857 13 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 21225350 Common - hypothetical protein SCO7067 33 COG1695 COG1695, Predicted transcriptional regulators Transcription 21224901 Common - secreted sugar binding protein SCO6601 110 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21225186 Nonpathogen - integral membrane protein SCO6896 2 None None None 21221867 Common - secreted protein SCO3441 2 None None None 21225449 Nonpathogen - hypothetical protein SCO7169 1 None None None 21220976 Nonpathogen - lipoprotein SCO2515 1 None None None 21221551 Common - hypothetical protein SCO3112 14 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 21221713 Common - hypothetical protein SCO3280 9 None None None 21219568 Common - regulatory protein SCO1052 15 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21221132 Common - hypothetical protein SCO2676 64 COG0824 FcbC, Predicted thioesterase General function prediction only 21221785 Common - ECF sigma factor SCO3356 81 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21223962 Common - transcriptional regulator SCO5607 25 COG2188 PhnF, Transcriptional regulators Transcription 32141333 Common - flavin-binding monooxygenase SCO7468 75 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21221702 Common - gntR-family regulator SCO3269 110 COG2188 PhnF, Transcriptional regulators Transcription 21218616 Common - sigma factor SCO0037 43 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21224661 Common - hypothetical protein SCO6348 13 None None None 21224473 Common aldo alditol oxidase SCO6147 75 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21219795 Common - hypothetical protein SCO1287 45 COG2898 COG2898, Uncharacterized conserved protein Function unknown 21222829 Common - DNA-binding protein SCO4441 6 COG1396 HipB, Predicted transcriptional regulators Transcription 21220290 Nonpathogen - hypothetical protein SCO1799 5 None None None 21221371 Common - regulator SCO2924 8 None None None 21223751 Common - ATP/GTP-binding protein, doubtful CDS SCO5391 14 None None None 21225847 Common - secreted hydrolase SCO7583 11 None None None 21221378 Common - ABC transporter ATP-binding protein SCO2931 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 21225136 Common - DNA methylase SCO6844 23 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 21220412 Common - DNA-binding protein SCO1926 43 COG2345 COG2345, Predicted transcriptional regulator Transcription 21222283 Common - hypothetical protein SCO3875 18 COG5512 COG5512, Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives General function prediction only 21225457 Nonpathogen - transcriptional regulatory protein SCO7178 6 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225263 Common - hypothetical protein SCO6977 13 None None None 21221650 Nonpathogen - hypothetical protein SCO3215 3 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221775 Common - dihydroxy-acid dehydratase SCO3345 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 21221172 Nonpathogen - secreted protein SCO2718 1 None None None 21224182 Common - protease SCO5838 112 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 21224794 Common - acetyltransferase SCO6490 75 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21220262 Common - hypothetical protein SCO1770 105 COG1354 COG1354, Uncharacterized conserved protein Function unknown 21222466 Nonpathogen - secreted protein SCO4063 1 None None None 21220573 Common - hypothetical protein SCO2093 49 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 21222222 Common - gntR-family transcriptional regulator SCO3812 138 COG1725 COG1725, Predicted transcriptional regulators Transcription 21224910 Common - hydrolase SCO6612 105 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21222130 Common - potassium-transporting ATPase subunit B SCO3717 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 21218875 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SCO0330 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21219895 Common - phosphoenolpyruvate-protein phosphotransferase SCO1391 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 21225592 Common - integral membrane protein SCO7316 7 None None None 21222794 Common - ABC transport system ATP-binding protein SCO4405 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21224412 Common - hypothetical protein SCO6083 2 None None None 21220882 Common - secreted protein SCO2416 11 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 21219106 Common - cytosine permease SCO0572 64 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 21225394 Common - ECF-family RNA polymerase sigma factor SCO7112 43 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21218751 Nonpathogen - lipoprotein SCO0195 6 None None None 21219376 Common - acetyltransferase SCO0855 12 COG3153 COG3153, Predicted acetyltransferase General function prediction only 21223061 Common - short chain dehydrogenase SCO4681 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221062 Nonpathogen - secreted protein SCO2604 1 None None None 21221530 Common - ABC transporter integral membrane protein SCO3090 190 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 21219346 Nonpathogen - transmembrane transport protein SCO0825 2 None None None 21222845 Common - integral membrane protein SCO4457 54 COG1808 COG1808, Predicted membrane protein Function unknown 21219274 Nonpathogen - hypothetical protein SCO0750 1 None None None 21223518 Common - protease SCO5149 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21221513 Common - allantoate amidohydrolase SCO3072 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 21225413 Common - lipase SCO7131 119 COG0657 Aes, Esterase/lipase Lipid metabolism 21225587 Common - probable amino acid decarboxylase SCO7311 90 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 21225129 Common - arsenic resistance membrane transport protein SCO6837 133 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 21224969 Common - hypothetical protein SCO6673 34 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 21225682 Common - pyruvate decarboxylase SCO7412 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 21223141 Common groEL chaperonin GroEL SCO4762 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 21221383 Common - hypothetical protein SCO2936 39 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 21221040 Nonpathogen - membrane protein SCO2581 1 None None None 21223951 Common - signal peptidase I SCO5596 57 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 21219748 Nonpathogen - hypothetical protein 2SCG114 SCO1239 1 None None None 21224132 Common - hypothetical protein SCO5787 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 21225107 Common - ABC transporter ATP-binding protein SCO6814 245 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 21222401 Common - hypothetical protein 2SC10A702c SCO3998 4 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 21221525 Common - 4-hydroxybenzoate 3-monooxygenase SCO3084 63 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21221107 Nonpathogen - secreted protein SCO2650 1 None None None 21224811 Common - gas vesicle synthesis protein SCO6508 19 None None None 21218704 Common - secreted protein SCO0145 23 COG2267 PldB, Lysophospholipase Lipid metabolism 21221038 Common nadD nicotinic acid mononucleotide adenyltransferase SCO2579 182 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 21220213 Common - ABC-transporter ATP-binding protein SCO1719 248 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21221666 Common - hydrolase SCO3233 147 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21223440 Common - tetR-family transcriptional regulator SCO5068 31 COG1309 AcrR, Transcriptional regulator Transcription 21224490 Common - hypothetical protein SCO6164 59 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 21225652 Nonpathogen - hypothetical protein SCO7379 1 None None None 21220325 Common - stress-like protein SCO1836 38 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 21220642 Common - hypothetical protein SCO2168 37 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 21222699 Nonpathogen - hypothetical protein SCO4306 1 None None None 21223514 Common - hypothetical protein SCO5145 16 None None None 21225777 Common - glyceraldehyde 3-phosphate dehydrogenase SCO7511 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 21222893 Common - cell division-related protein SCO4508 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21225746 Common - phosphotransferase SCO7478 26 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 21223425 Nonpathogen - hypothetical protein SCO5052 1 None None None 21219487 Common - reductase SCO0969 53 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 21221607 Common - short chain dehydrogenase SCO3170 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 32141261 Common rho transcription termination factor Rho SCO5357 207 COG1158 Rho, Transcription termination factor Transcription 21222961 Nonpathogen - hypothetical protein SCO4578 1 None None None 21223915 Common - glycerol-3-phosphate dehydrogenase SCO5559 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 21225896 Nonpathogen - secreted extracellular small neutral protease SCO7635 3 None None None 21224802 Nonpathogen - gas vesicle synthesis protein SCO6499 1 None None None 32141147 Common - glycerophosphoryl diester phosphodiesterase SCO1565 95 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 21223776 Common - transcriptional regulator SCO5416 107 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21224483 Nonpathogen - transmembrane protein SCO6157 1 None None None 21220154 Common - glycerol operon regulatory protein SCO1658 119 COG1414 IclR, Transcriptional regulator Transcription 21222024 Nonpathogen - hypothetical protein SCO3608 2 None None None 21222075 Common - hypothetical protein SCO3660 23 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 21218824 Common - alpha-galactosidase SCF8502 SCO0274 42 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 21225000 Common - glutathione-dependent aldehyde dehydrogenase SCO6706 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21223419 Common - hypothetical protein SCO5046 18 None None None 21220668 Nonpathogen - hypothetical protein SCO2195 1 None None None 32141188 Common - hypothetical protein SCO2999 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 21225034 Common - D-amino acid oxidase SCO6740 32 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 21223619 Common - hypothetical protein SCO5252 34 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 21218799 Common - integral membrane protein SCO0246 215 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21222813 Nonpathogen - sigma-like protein SCO4425 1 None None None 21220719 Nonpathogen - hypothetical protein SCO2249 1 None None None 21221812 Common - hypothetical protein SCO3384 45 COG5495 COG5495, Uncharacterized conserved protein Function unknown 21219711 Common - regulatory protein SCO1200 106 COG1396 HipB, Predicted transcriptional regulators Transcription 21221321 Common - hypothetical protein SCO2872 76 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 21223042 Common - elongation factor G SCO4661 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 21219234 Common - branched-chain amino acid ABC transport protein SCO0708 119 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 21223879 Common - transmembrane transport protein SCO5524 7 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 21222906 Nonpathogen - secreted protein SCO4521 2 None None None 21222267 Common - hypothetical protein SCO3858 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 21225331 Common - delta fatty acid desaturase SCO7048 22 COG3239 DesA, Fatty acid desaturase Lipid metabolism 21220893 Common - phosphate binding protein (secreted protein) SCO2428 86 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 21221962 Common - probable DNA topoisomerase I SCO3543 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 21220914 Common - serine/threonine protein kinase (regulator) SCO2450 80 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21224484 Nonpathogen - hypothetical protein SCO6158 2 None None None 21223287 Common - aldehyde dehydrogenase SCO4913 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 32141158 Common - quinolinate synthetase SCO2162 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 21225052 Common - phytoene synthase SCO6759 78 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 21223166 Common - hypothetical protein SCO4787 125 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 21220864 Common - oxidoreductase SCO2397 105 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 21223228 Common - integral membrane protein SCO4852 6 None None None 21219594 Nonpathogen - hypothetical protein SCO1079 1 None None None 21225151 Nonpathogen - hypothetical protein SCO6860 1 None None None 21221891 Common - transposase SCO3467 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21223302 Common - adenylate cyclase SCO4928 9 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 21220766 Common - hypothetical protein SCO2297 23 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 21225656 Nonpathogen - hypothetical protein SCO7383 1 None None None 21218779 Nonpathogen - hypothetical protein SCO0226 1 None None None 21220432 Common - glyceraldehyde-3-phosphate dehydrogenase SCO1947 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 21219212 Common - hypothetical protein SCO0683 11 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21224389 Common - hypothetical protein SCO6059 5 None None None 21223708 Common - replication initiation protein SCO5347 5 None None None 21223540 Common - hypothetical protein SCO5171 3 None None None 21218994 Common - probable secreted solute-binding lipoprotein SCO0453 31 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21218767 Common - nitrate/nitrite transporter protein SCO0213 89 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 21223758 Common - hypothetical protein SCO5398 88 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 21224101 Common - hypothetical protein SCO5755 17 None None None 21220298 Common - phosphoserine phosphatase SCO1808 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 21219942 Common ribH riboflavin synthase subunit beta SCO1440 224 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 21223747 Nonpathogen - large hypothetical protein SCO5387 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 21224594 Common - type I polyketide synthase SCO6274 211 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21224828 Nonpathogen - hypothetical protein SCO6526 1 None None None 21225439 Common - integral membrane protein SCO7159 10 COG1289 COG1289, Predicted membrane protein Function unknown 21224275 Nonpathogen - hypothetical protein SCO5937 3 None None None 21225421 Common - hypothetical protein SCO7141 45 COG0778 NfnB, Nitroreductase Energy production and conversion 21219081 Common - pyruvate carboxylase SCO0546 233 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 21224127 Common - transmembrane transport protein SCO5782 99 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 21222327 Common - low molecular weight protein-tyrosine-phosphatase SCO3921 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 21221981 Common - integral membrane transport protein SCO3562 182 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 21219719 Common - acyl-CoA dehydrogenase SCO1209 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21218790 Common - oxidoreductase SCO0237 219 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 21221873 Nonpathogen - hypothetical protein SCO3448 1 None None None 21224786 Common - hypothetical protein SCO6482 7 None None None 21221179 Nonpathogen - lipoprotein SCO2725 3 None None None 21223502 Common - two-component system response regulator SCO5132 192 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21218892 Common - 2-hydroxyacid-family dehydrogenase SCO0348 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 21223813 Common - two-component system response regulator SCO5455 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219599 Common - thioredoxin SCO1084 11 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 21220522 Nonpathogen - hypothetical protein SCO2041 1 None None None 21219911 Nonpathogen - membrane protein SCO1408 4 None None None 21221826 Common - hypothetical protein SCO3399 13 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 21222968 Common - ABC transporter ATP-binding protein SCO4585 244 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21225489 Common - secreted glycosyl hydrolase SCO7212 119 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 21220491 Common - branched chain amino acid transport permease SCO2009 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 21223809 Common - ABC transporter SCO5451 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21223373 Nonpathogen - hypothetical protein SCO5000 1 None None None 21220948 Common - hypothetical protein SCO2485 72 COG0730 COG0730, Predicted permeases General function prediction only 21221699 Nonpathogen - hypothetical protein SCO3266 1 None None None 21221070 Common - nucleoside diphosphate kinase SCO2612 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 21225554 Nonpathogen - regulator protein SCO7277 1 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 21220044 Common - hypothetical protein SCO1544 40 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 21221191 Common - hypothetical protein SCO2738 4 None None None 21219373 Common - aldolase SCO0852 123 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 21224497 Common - oxidoreductase SCO6172 114 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 21220753 Common - membrane transport protein SCO2284 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225826 Common - transcriptional regulator SCO7562 115 COG1414 IclR, Transcriptional regulator Transcription 21225270 Common - oxidoreductase SCO6984 100 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21219684 Common - transcriptional regulator SCO1173 77 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 21225256 Common - integral membrane protein SCO6969 38 COG0730 COG0730, Predicted permeases General function prediction only 21218810 Common - hypothetical protein SCO0258 14 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 21223327 Nonpathogen - hypothetical protein 2SCK3114c SCO4954 6 None None None 21224266 Nonpathogen - hypothetical protein SCO5927 1 None None None 21218595 Common - hypothetical protein SCO0013 3 None None None 21223192 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase SCO4814 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 21224568 Common - allantoinase SCO6247 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 21225863 Common - alanyl tRNA synthetase SCO7600 242 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21226050 Common - transposase SCO7798 44 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220740 Common - hypothetical protein SCO2271 6 None None None 21223093 Common rplX 50S ribosomal protein L24 SCO4713 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 21221731 Common - hypothetical protein SCO3299 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 21226039 Nonpathogen - hypothetical protein SCO7788 1 None None None 21222803 Common - integral membrane transport protein SCO4414 134 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21220010 Common - hydrolase SCO1509 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21219364 Common - hypothetical protein SCO0843 7 None None None 21221939 Nonpathogen - hypothetical protein SCO3518 1 None None None 32141243 Common - DNA-directed RNA polymerase subunit beta' SCO4655 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 21224344 Common - solute-binding protein SCO6009 106 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 21222386 Nonpathogen - hypothetical protein SCO3982 1 None None None 21222031 Common - aspartate kinase SCO3615 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 21222429 Common - ATP binding protein SCO4026 11 None None None 21224877 Common - hypothetical protein SCO6576 5 None None None 21225693 Common - hypothetical protein SCO7423 14 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 21224894 Nonpathogen - secreted protein SCO6594 8 None None None 21218900 Common - probable oxidoreductase SCO0356 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21220676 Common - hypothetical protein SCO2203 13 None None None 21223447 Common - integral membrane protein SCO5076 172 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225965 Common - DNA-binding protein SCO7706 42 COG1396 HipB, Predicted transcriptional regulators Transcription 21218924 Common - glycosyl transferase SCO0381 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 21219825 Nonpathogen - hypothetical protein SCO1318 1 None None None 32141258 Common - magnesium chelatase SCO5277 66 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 21224892 Nonpathogen - secreted protein SCO6592 1 None None None 21226053 Nonpathogen - hypothetical protein SCO7801 1 None None None 21221478 Common - hypothetical protein SCO3035 8 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21222531 Common - secreted transglycosylase SCO4132 141 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21218657 Common - secreted beta-lactamase SCO0088 13 COG2367 PenP, Beta-lactamase class A Defense mechanisms 21222043 Common - secreted protein SCO3628 7 None None None 21225452 Nonpathogen - hypothetical protein SCO7172 1 None None None 21222009 Common - hypothetical protein SCO3593 34 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 21224041 Common - transcriptional regulator SCO5692 126 COG1609 PurR, Transcriptional regulators Transcription 21224277 Common - peptidylprolyl isomerase SCO5939 132 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 21224283 Common - transferase SCO5945 144 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 21224692 Common - hypothetical protein SCO6380 4 None None None 21224192 Common - tagatose 6-phosphate kinase SCO5848 32 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 21223485 Common - BldKC, ABC transport system integral membrane protein SCO5114 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21218866 Common - oxidoreductase SCO0318 109 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21220530 Common - hypothetical protein SCO2049 43 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21220309 Nonpathogen - integral membrane protein SCO1820 2 None None None 21221214 Nonpathogen - secreted protein SCO2762 1 None None None 21225357 Common - hypothetical protein SCO7074 40 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21224430 Nonpathogen - hypothetical protein SCO6101 5 None None None 21222363 Common - ABC transporter ATP-binding protein SCO3958 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21225759 Common - hypothetical protein SCO7491 73 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21219659 Common - marR-family regulator SCO1145 22 COG1846 MarR, Transcriptional regulators Transcription 21224868 Common - ABC transporter ATP-binding protein SCO6567 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 21223218 Common - oxidoreductase SCO4842 101 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21218846 Nonpathogen - secreted protein SCO0297 1 None None None 21220986 Nonpathogen - hypothetical protein SCO2525 2 None None None 21218812 Common - acetyltransferase SCO0261 76 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 21225689 Common - ATP/GTP binding protein SCO7419 31 COG2229 COG2229, Predicted GTPase General function prediction only 21219063 Common - lipoprotein SCO0528 9 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 32141138 Common - secreted alkaline phosphatase SCO1290 54 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 21223011 Common - regulator SCO4628 69 COG2188 PhnF, Transcriptional regulators Transcription 21221247 Common - cellobiose transport permease SCO2796 161 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21223414 Nonpathogen - hypothetical protein SCO5041 4 COG2306 COG2306, Uncharacterized conserved protein Function unknown 21225463 Common - branched amino acid transport system permease SCO7184 106 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 21226064 Common - TetR-family transcriptional regulator SCO7815 13 COG1309 AcrR, Transcriptional regulator Transcription 21224773 Common - acyl-CoA dehydrogenase SCO6469 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21219050 Common - hypothetical protein SCO0514 4 None None None 21218939 Common - hypothetical protein SCO0396 14 COG4310 COG4310, Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain General function prediction only 21219492 Common - 6-phosphogluconate dehydrogenase SCO0975 184 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 21219004 Common - integral membrane protein SCO0464 77 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221093 Nonpathogen - hypothetical protein SCO2636 2 None None None 21222524 Nonpathogen - acetyltransferase SCO4125 6 COG0456 RimI, Acetyltransferases General function prediction only 21219093 Common - hypothetical protein SCO0559 5 None None None 21220537 Nonpathogen - hypothetical protein SCO2056 1 None None None 21221424 Common - integral membrane transport protein SCO2980 165 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21225386 Common - RNA polymerase sigma factor SCO7104 41 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21219421 Nonpathogen - hypothetical protein SCO0901 5 None None None 21221334 Common - hypothetical protein SCO2885 80 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21221683 Common - integrase SCO3250 148 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 21222106 Common - hypothetical protein SCO3693 11 None None None 21223772 Common - hypothetical protein SCO5412 2 COG0011 COG0011, Uncharacterized conserved protein Function unknown 21222947 Common - NADH dehydrogenase subunit C SCO4564 174 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 21224883 Common - formyl-coenzyme A transferase SCO6583 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 21225084 Common - probable acyl-coA dehydrogenase SCO6791 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21226029 Nonpathogen - hypothetical protein SCO7776 1 None None None 21224515 Nonpathogen - hypothetical protein SCO6191 2 COG2327 WcaK, Uncharacterized conserved protein Function unknown 21219277 Nonpathogen - hypothetical protein SCO0753 1 None None None 21219304 Common - anti sigma factor antagonist SCO0781 17 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21219851 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SCO1345 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21219973 Common - transposase SCO1471 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219320 Common - secreted protein SCO0798 72 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 21224697 Common - integral membrane protein SCO6385 43 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21222253 Common - secreted protein SCO3844 28 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 21222002 Common - hypothetical protein SCO3585 5 None None None 21224349 Common - hypothetical protein SCO6015 6 None None None 21224238 Common - oxidase SCO5897 76 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 21223345 Common - dehydrogenase SCO4972 115 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 21220323 Nonpathogen - hypothetical protein SCO1834 1 None None None 21225630 Common - oxidoreductase SCO7356 161 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 21220120 Common - acetyltransferase SCO1624 14 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21225388 Common - hypothetical protein SCO7106 19 None None None 21223221 Common - integral membrane protein SCO4845 13 COG2246 COG2246, Predicted membrane protein Function unknown 21221060 Common - hypothetical protein SCO2602 8 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 21220027 Common - membrane transferase SCO1527 71 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 21221168 Nonpathogen - hypothetical protein SCO2713 7 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 21222030 Common - aspartate-semialdehyde dehydrogenase SCO3614 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 21222822 Common - LysR-family transcriptional regulator SCO4434 187 COG0583 LysR, Transcriptional regulator Transcription 21219340 Common - transmembrane transport protein SCO0819 5 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 32141288 Common mmuM homocysteine methyltransferase SCO6137 115 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 21220938 Common - lysR-family transcriptional regulator SCO2475 186 COG0583 LysR, Transcriptional regulator Transcription 21221050 Common - transferase SCO2592 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21225277 Nonpathogen - hypothetical protein SCO6991 1 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 21218832 Common - deoR family transcriptional regulator SCO0282 114 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 21223021 Nonpathogen - hypothetical protein SCO4639 3 COG1309 AcrR, Transcriptional regulator Transcription 21224757 Common - substrate binding protein SCO6451 204 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21222738 Nonpathogen - hypothetical protein SCO4347 2 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 21222518 Common - NADH dehydrogenase SCO4119 148 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 21221016 Common - hypothetical protein SCO2557 15 None None None 21222555 Common - protease SCO4157 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21225614 Common - hypothetical protein SCO7339 28 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21220857 Common - 3-oxoacyl-(ACP) synthase II SCO2390 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21221623 Common - 5'-methylthioadenosine phosphorylase SCO3188 128 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 21219243 Common - integral membrane protein SCO0717 37 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21224732 Common - hypothetical protein SCO6425 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21224437 Common - esterase SCO6108 31 None None None 21223887 Common - transcriptional regulator SCO5532 61 COG1309 AcrR, Transcriptional regulator Transcription 21219112 Common - ribose 5-phosphate isomerase SCO0579 122 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 21225480 Common - integral membrane protein SCO7203 7 None None None 21222784 Common - iron repressor SCO4394 84 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 21225064 Nonpathogen - small hydrophobic secreted protein SCO6771 1 None None None 21225482 Common - hydrolase SCO7205 84 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21220186 Common - tetR transcriptional regulator SCO1691 143 COG1309 AcrR, Transcriptional regulator Transcription 21220243 Common - acyl CoA dehydrogenase SCO1750 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21225120 Common - secreted protein SCO6828 22 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21223314 Nonpathogen - hypothetical protein SCO4941 1 None None None 21221549 Common - ABC transport system integral membrane protein SCO3110 80 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 21219242 Common - glycosyl hydrolase (secreted protein) SCO0716 10 None None None 21223699 Nonpathogen - regulatory protein SCO5338 1 None None None 21218999 Common - Beta-glucosidase SCO0458 94 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21220884 Common - secreted protein SCO2418 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 21219318 Common - integral membrane protein SCO0796 11 COG4129 COG4129, Predicted membrane protein Function unknown 21220738 Common - hypothetical protein SCO2269 4 None None None 21225089 Common - hypothetical protein SCO6796 9 None None None 21219094 Common - catalase/peroxidase SCO0560 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 21220661 Common - hypothetical protein SCO2187 13 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 21219876 Common - oxidoreductase SCO1371 111 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 21221469 Common - hypothetical protein SCO3026 10 None None None 21218758 Common - hypothetical protein SCO0202 6 None None None 21218672 Nonpathogen - hypothetical protein SCO0108 1 None None None 21220282 Common - hypothetical protein SCO1790 18 None None None 21222394 Nonpathogen - hypothetical protein SCO3990 1 None None None 21220731 Common - oxidoreductase SCO2262 47 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 21225471 Common - sigma factor SCO7192 43 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21219774 Common - 3-oxoacyl-(ACP) synthase II SCO1266 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21220611 Common - hypothetical protein SCO2134 7 None None None 21223068 Common - hypothetical protein SCO4688 10 COG0789 SoxR, Predicted transcriptional regulators Transcription 21220419 Common - hypothetical protein SCO1933 3 None None None 21222581 Nonpathogen - aerial mycelium formation SCO4184 4 None None None 21219789 Common - oxidoreductase SCO1281 51 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 21218839 Common - probable transcriptional regulator SCO0289 125 COG1609 PurR, Transcriptional regulators Transcription 21223382 Common - secretory protein SCO5009 227 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 21220687 Common - two-component system sensor kinase SCO2215 104 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220478 Common - dephospho-CoA kinase SCO1996 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 21221483 Common - secreted protein SCO3040 15 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 21224386 Nonpathogen - secreted protein SCO6056 1 None None None 21220627 Common - cytochrome C heme-binding subunit SCO2150 54 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 21225565 Common - membrane protein SCO7288 10 None None None 21221405 Nonpathogen - integral membrane protein SCO2960 1 COG5028 COG5028, Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 Intracellular trafficking and secretion 21225096 Common - acetyltransferase SCO6803 27 COG0456 RimI, Acetyltransferases General function prediction only 21222082 Common - heat shock protein SCO3668 56 COG0789 SoxR, Predicted transcriptional regulators Transcription 21222450 Common - hypothetical protein SCO4047 11 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 21224083 Common rpsO 30S ribosomal protein S15 SCO5736 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 21220147 Common - hypothetical protein SCO1651 59 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 21220192 Common - merR-family transcriptional regulator SCO1697 51 COG0789 SoxR, Predicted transcriptional regulators Transcription 21223404 Common - alkyl hydroperoxide reductase system hypothetical protein SCO5031 27 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21219513 Common - lipoprotein SCO0996 112 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 21221831 Common - cell division protein ftsH homolog SCO3404 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 21221026 Common - integral membrane protein SCO2567 117 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 21222173 Nonpathogen - hypothetical protein SCO3762 1 None None None 21223525 Nonpathogen - hypothetical protein SCO5156 2 None None None 21225813 Nonpathogen - hypothetical protein SCO7549 1 None None None 21218801 Nonpathogen - hypothetical protein SCO0248 1 None None None 21219269 Common - tetR-family transcriptional regulator SCO0745 6 COG1309 AcrR, Transcriptional regulator Transcription 21218907 Common - integral membrane protein SCO0363 6 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21222246 Common - hypothetical protein SCO3837 10 None None None 21221457 Common - translation initiation factor SCO3014 128 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 21222221 Common - D-alanyl-D-alanine carboxypeptidase SCO3811 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 21219583 Common - hypothetical protein SCO1068 9 None None None 32141345 Nonpathogen - hypothetical protein SCO7843 5 None None None 21219076 Common - alpha-galactosidase SCO0541 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 21220119 Common - hypothetical protein SCO1623 62 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 21220771 Nonpathogen - hypothetical protein SCO2302 2 None None None 21220797 Common - transcriptional regulator SCO2329 136 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21219633 Common - asnC-family transcriptional regulatory protein SCO1119 154 COG1522 Lrp, Transcriptional regulators Transcription 21223049 Common - two-component system response regulator SCO4668 128 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21224290 Nonpathogen - hypothetical protein SCO5952 4 None None None 21223898 Common - hypothetical protein SCO5543 13 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21219923 Common - integral membrane protein SCO1420 66 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 21220500 Common - aminopeptidase SCO2018 162 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 21222503 Common - MerR family transcriptional regulator SCO4102 98 COG0789 SoxR, Predicted transcriptional regulators Transcription 21223496 Common - hypothetical protein SCO5126 25 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 21218601 Nonpathogen - hypothetical protein SCO0019 1 None None None 21223360 Common - D-amino acid deaminase SCO4987 47 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 21224095 Common - two-component regulator SCO5749 221 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 21224249 Nonpathogen - hypothetical protein SCO5910 1 None None None 21223996 Common - hypothetical protein SCO5645 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 21219677 Nonpathogen - hypothetical protein SCO1164 1 None None None 21222051 Common - cytochrome P-450 hydroxylase SCO3636 79 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21225666 Common - membrane transport protein SCO7395 152 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224301 Common - hypothetical protein SCO5963 6 None None None 21223631 Common - hypothetical protein SCO5264 58 COG1695 COG1695, Predicted transcriptional regulators Transcription 21219009 Common - hypothetical protein SCO0469 70 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21225283 Nonpathogen - hypothetical protein SCO6997 3 None None None 21221320 Common - hypothetical protein SCO2871 16 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 21225850 Common - oxidoreductase SCO7586 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 21220358 Common - hypothetical protein SCO1870 21 COG3506 COG3506, Uncharacterized conserved protein Function unknown 21222404 Common - hypothetical protein 2SC10A705c SCO4001 7 None None None 21225929 Common - oxidoreductase SCO7669 12 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21220802 Nonpathogen - integral membrane protein SCO2334 5 None None None 21220901 Nonpathogen - integral membrane protein SCO2437 2 None None None 21223739 Common - hypothetical protein SCO5379 13 None None None 21220999 Common - carbohydrate kinase SCO2540 153 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21221170 Nonpathogen - hypothetical protein SCO2715 7 COG3919 COG3919, Predicted ATP-grasp enzyme General function prediction only 21219059 Common - gluconolactonase precursor SCO0524 80 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 21223790 Common - secreted nucleosidase SCO5431 12 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 21224163 Common - sporulation transcription factor, WhiH SCO5819 97 COG2186 FadR, Transcriptional regulators Transcription 21221721 Nonpathogen - large membrane protein SCO3289 1 None None None 21222731 Common - reductase SCO4339 183 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21221993 Common - hypothetical protein SCO3575 91 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21219174 Common - membrane protein SCO0644 5 COG5373 COG5373, Predicted membrane protein Function unknown 21221369 Common - hypothetical protein SCO2922 8 COG1714 COG1714, Predicted membrane protein/domain Function unknown 21223562 Nonpathogen - secreted protein SCO5193 4 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 21225574 Common - thioredoxin reductase SCO7298 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 21223727 Common - ATP synthase A chain SCO5367 202 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 21222935 Common - hydrolase SCO4552 20 None None None 21224763 Common - beta-galactosidase SCO6457 77 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21225402 Common - ubiquinol-cytochrome C reductase cytochrome B subunit SCO7120 143 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 21224051 Nonpathogen - lipoprotein SCO5702 1 None None None 21224111 Common - hypothetical protein SCO5765 7 None None None 21225580 Common - putative FAD-binding dehydrogenase SCO7304 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 21218608 Nonpathogen - hypothetical protein SCO0029 1 None None None 21226010 Common - anti-sigma factor antagonist SCO7754 4 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21219882 Common - molibdenum binding protein SCO1377 57 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 21220727 Common - probable ABC-transporter, transmembrane component SCO2258 84 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21221978 Common - oxidoreductase SCO3559 9 COG3177 COG3177, Uncharacterized conserved protein Function unknown 21225174 Nonpathogen - hypothetical protein SCO6883 1 None None None 21220106 Common - hypothetical protein SCO1609 14 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 21223148 Common - RNA polymerase sigma factor SigD SCO4769 75 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220406 Common - hypothetical protein SCO1920 167 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 21223242 Nonpathogen - hypothetical protein SCO4867 1 None None None 21218731 Common - DNA-binding protein SCO0174 13 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21219260 Common - oxidoreductase SCO0735 135 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21219193 Common - 2-hydroxyacid-family dehydrogenase SCO0663 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 21223369 Common - RNA polymerase ECF sigma factor SCO4996 9 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21221741 Nonpathogen - hypothetical protein SCO3310 1 None None None 21222809 Nonpathogen - hypothetical protein SCO4420 1 None None None 21225322 Common - ABC transporter ATP-binding protein SCO7039 117 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 21219754 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase SCO1245 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 21221006 Common - ribonuclease Z SCO2547 123 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 21223176 Common - peptidase SCO4798 185 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21219119 Common - hypothetical protein SCO0586 8 None None None 21223730 Common - ATP synthase delta chain SCO5370 71 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 21222722 Common - hypothetical protein SCO4330 18 None None None 21221089 Common - transposase SCO2632 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219733 Common - ornithine aminotransferase SCO1223 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 21220509 Nonpathogen - hypothetical protein SCO2028 2 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21226068 Common - integral membrane protein SCO7819 13 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 21225169 Common - ATP-binding protein SCO6878 13 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 21222420 Common - iron dependent repressor SCO4017 66 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 21219271 Common - hypothetical protein SCO0747 52 COG0622 COG0622, Predicted phosphoesterase General function prediction only 21223110 Common truA tRNA pseudouridine synthase A SCO4731 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 21222656 Nonpathogen - hypothetical protein SCO4262 1 None None None 21223406 Common - hydrogen peroxide sensing regulator SCO5033 169 COG0583 LysR, Transcriptional regulator Transcription 21224722 Common - dihydropyrimidinase SCO6415 198 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 21219451 Common - integral membrane protein SCO0932 8 None None None 21219329 Common - hypothetical protein SCO0807 40 COG3254 COG3254, Uncharacterized conserved protein Function unknown 21221995 Common - ion-transporting ATPase SCO3577 13 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 21220662 Common - peptidase (secreted protein) SCO2188 66 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21223985 Nonpathogen - hypothetical protein SCO5632 1 None None None 21218964 Common - two-component sensor kinase SCO0422 58 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223240 Nonpathogen - hypothetical protein SCO4865 1 None None None 21219086 Common - histidine kinase protein SCO0551 98 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21224222 Common - acyl-coa dehydrogenase RedW SCO5879 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21223729 Common - F0F1 ATP synthase subunit B SCO5369 28 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 21225979 Common - hypothetical protein SCO7720 6 None None None 21221564 Nonpathogen - hypothetical protein SCO3126 1 None None None 21222214 Common - araC-family transcriptional regulator SCO3804 112 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21219617 Nonpathogen - integral membrane protein SCO1102 1 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21219672 Common - hypothetical protein SCO1159 17 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21220585 Common - oxidoreductase SCO2106 197 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 21225149 Nonpathogen - hypothetical protein SCO6858 1 None None None 21225047 Common - glycerol dehydrogenase SCO6754 115 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 21221347 Nonpathogen - membrane protein SCO2900 1 None None None 21222870 Nonpathogen - integral membrane protein SCO4484 2 None None None 21223183 Common - hypothetical protein SCO4805 25 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 21218723 Common - regulator SCO0166 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 21219939 Common - secreted protein SCO1436 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21225947 Common - thioesterase SCO7687 50 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21223948 Common - 16S rRNA processing protein SCO5593 115 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 21224800 Common - transketolase SCO6497 223 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 21225310 Common - probable LysR-family transcriptional regulator SCO7025 150 COG0583 LysR, Transcriptional regulator Transcription 21219359 Common - hypothetical protein SCO0838 8 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 21218948 Common - hypothetical protein SCO0406 11 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 21220372 Common - oxidoreductase SCO1885 44 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21224175 Common - citrate synthase-like protein SCO5831 121 COG0372 GltA, Citrate synthase Energy production and conversion 21222411 Common - tetR family regulatory protein SCO4008 16 COG1309 AcrR, Transcriptional regulator Transcription 21220862 Common - integral membrane protein SCO2395 6 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 21225524 Common - hypothetical protein SCO7247 12 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21220429 Nonpathogen secG preprotein translocase subunit SecG SCO1944 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 21223298 Nonpathogen - hypothetical protein SCO4924 1 None None None 21222611 Common - GntR-family regulatory protein SCO4215 138 COG2188 PhnF, Transcriptional regulators Transcription 21221805 Common - N-acetylglutamate synthase SCO3376 98 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 21224541 Common - phosphatase SCO6218 164 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21221115 Common - sugar transport system permease protein SCO2659 155 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222577 Common - iron uptake regulatory protein SCO4180 188 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 21221913 Nonpathogen - transmembrane protein SCO3491 1 None None None 21223119 Common - D-fructose-6-phosphate amidotransferase SCO4740 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 21221498 Common - hypothetical protein SCO3056 14 None None None 21224850 Common - secreted cellulase SCO6548 19 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 21218650 Common - integral membrane transport protein SCO0079 142 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219049 Common - integral membrane protein SCO0513 62 COG0628 PerM, Predicted permease General function prediction only 21223762 Nonpathogen - Asp-rich hydrophilic protein (putative membrane protein) SCO5402 1 COG3212 COG3212, Predicted membrane protein Function unknown 21223564 Common - hypothetical protein SCO5195 37 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21223501 Common - two-component system sensor kinase SCO5131 37 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21221888 Common - phosphorylase SCO3463 129 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 21222684 Nonpathogen - secreted protein SCO4291 1 None None None 21219836 Common - fatty acid CoA ligase SCO1330 8 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21220422 Common - transaldolase SCO1936 102 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 21221436 Common - acetyltransferase SCO2992 5 None None None 21223931 Common - transmembrane protein SCO5575 74 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 32141214 Common - regulatory protein SCO3723 90 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225501 Common - integral membrane protein SCO7224 29 COG2259 COG2259, Predicted membrane protein Function unknown 21220983 Nonpathogen - hypothetical protein SCO2522 2 None None None 21221851 Common - regulator SCO3424 6 None None None 21222302 Common - hypothetical protein SCO3895 14 None None None 21220805 Nonpathogen - acetyltransferase SCO2337 1 COG0456 RimI, Acetyltransferases General function prediction only 21218680 Nonpathogen - small secreted protein SCO0119 1 None None None 21223278 Nonpathogen - integral membrane protein SCO4904 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 32141267 Common - nitrogen regulatory protein P-II SCO5584 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 21224854 Common - long-chain-fatty-acid-CoA ligase SCO6552 215 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 21221934 Nonpathogen - secreted protein SCO3513 1 None None None 21222779 Common - acetyltransferase SCO4389 74 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21222867 Common - tetR-family transcriptional regulatory protein SCO4480 66 COG1309 AcrR, Transcriptional regulator Transcription 21223508 Common - dipeptidase SCO5139 171 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 21224582 Nonpathogen - probable secreted protein SCO6261 1 None None None 21219853 Nonpathogen - secreted protein SCO1347 1 None None None 21224113 Common - hypothetical protein SCO5767 111 COG0628 PerM, Predicted permease General function prediction only 21224462 Nonpathogen - hypothetical protein SCO6135 1 None None None 21225815 Nonpathogen - secreted protein SCO7551 1 None None None 21220352 Common - acetyltransferase SCO1864 29 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21224444 Common - hypothetical protein SCO6117 48 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 21225616 Common - RNA polymerase secondary sigma factor SCO7341 214 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21220877 Nonpathogen - integral membrane protein SCO2410 2 None None None 21223398 Common - transcriptional regulator SCO5025 56 COG0789 SoxR, Predicted transcriptional regulators Transcription 21219468 Common - transport system permease protein SCO0950 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219772 Common - hydrolase SCO1264 56 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 32141313 Common - integral membrane transferase SCO6752 4 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 21218741 Common - hypothetical protein SCO0184 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 21222758 Common - oxidoreductase SCO4367 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21222772 Common - acyl CoA dehydrogenase SCO4382 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21221276 Nonpathogen - hypothetical protein SCO2826 1 None None None 21218898 Common - binding-protein-dependent transport protein SCO0354 157 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21218786 Common - DNA-binding protein SCO0233 41 None None None 21220476 Nonpathogen - integral membrane protein SCO1994 1 None None None 21223108 Common - DNA-directed RNA polymerase subunit alpha SCO4729 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 21222270 Common - hypothetical protein SCO3861 2 None None None 32141247 Common - hypothetical protein SCO4816 9 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 21223684 Common - polyketide hydroxylase SCO5321 83 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21224633 Nonpathogen - hypothetical protein SCO6317 1 None None None 21225208 Nonpathogen - hypothetical protein SCO6920 1 None None None 21220782 Nonpathogen - integral membrane protein SCO2314 2 None None None 21220059 Common - phosphatase SCO1560 179 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 21221285 Nonpathogen - membrane protein SCO2835 2 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21224014 Nonpathogen - integral membrane protein SCO5663 1 None None None 21225133 Common - hypothetical protein SCO6841 15 COG3586 COG3586, Uncharacterized conserved protein Function unknown 21223645 Nonpathogen - hypothetical protein SCO5279 2 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 21224743 Common - hypothetical protein SCO6437 37 COG0439 AccC, Biotin carboxylase Lipid metabolism 21223792 Common - AfsR-like regulator SCO5433 25 COG3903 COG3903, Predicted ATPase General function prediction only 21224396 Common - ATP/GTP-binding protein SCO6066 32 COG2229 COG2229, Predicted GTPase General function prediction only 21221351 Common rph ribonuclease PH SCO2904 187 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 21218850 Common - lipoprotein SCO0301 29 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 21224288 Common - export protein SCO5950 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224031 Nonpathogen - integral membrane protein SCO5682 2 COG5650 COG5650, Predicted integral membrane protein Function unknown 21219185 Common - gas vesicle synthesis protein SCO0655 14 None None None 21222669 Common - response regulatory protein SCO4276 179 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21225009 Common - transcriptional regulator SCO6715 19 None None None 21220859 Nonpathogen - lipoprotein SCO2392 4 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21220268 Common - CTP synthetase SCO1776 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 21223868 Common - acetolactate synthase 1 catalytic subunit SCO5512 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 21223279 Nonpathogen - lipoprotein SCO4905 1 None None None 21225115 Common - integral membrane efflux protein SCO6822 195 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21225370 Common - two-component system response regulator SCO7088 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223332 Nonpathogen - hypothetical protein SCO4959 1 None None None 21223842 Nonpathogen - small hydrophobic membrane protein SCO5485 1 None None None 21220841 Common - transcriptional regulator SCO2374 81 COG1309 AcrR, Transcriptional regulator Transcription 21219998 Nonpathogen - integral membrane protein SCO1497 1 None None None 21222816 Nonpathogen - secreted protein SCO4428 16 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 21222384 Nonpathogen - hypothetical protein SCO3980 1 None None None 21225888 Common - monooxygenase SCO7626 106 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21225346 Common - hypothetical protein SCO7063 101 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21224648 Nonpathogen - very hypothetical protein SC3A703c SCO6335 1 None None None 21219710 Common - oxidoreductase SCO1199 134 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21219558 Common - hypothetical protein SCO1042 6 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 21222427 Common - integral membrane efflux protein SCO4024 184 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224310 Common - phosphatase SCO5973 118 COG4639 COG4639, Predicted kinase General function prediction only 21221840 Common - transcriptional regulator SCO3413 70 COG0789 SoxR, Predicted transcriptional regulators Transcription 21221617 Common - molybdopterin biosynthesis protein SCO3181 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 32141161 Common - hypothetical protein SCO2206 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 21221905 Common - hypothetical protein SCO3481 6 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 21220288 Common - integral membrane protein SCO1797 17 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21225893 Common - hypothetical protein SCO7632 28 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 21220952 Common - tetR-family transcriptional regulator SCO2489 91 COG1309 AcrR, Transcriptional regulator Transcription 21223249 Common - integral membrane protein SCO4874 5 COG4485 COG4485, Predicted membrane protein Function unknown 21225025 Common - acetyl-CoA acetyltransferase SCO6731 181 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21224263 Common - probable integral membrane protein SCO5924 211 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 21218954 Nonpathogen - hypothetical protein SCO0412 1 None None None 21221340 Common - hypothetical protein SCO2893 12 None None None 21218887 Nonpathogen - hypothetical protein SCO0343 1 None None None 21221952 Nonpathogen - hypothetical protein SCO3531 1 None None None 21221836 Common - inorganic pyrophosphatase SCO3409 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 32141228 Common - thiosulfate sulfurtransferase SCO4164 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 21220437 Common - hypothetical protein SCO1952 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 21225789 Common - chaperone SCO7523 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 21221476 Common - integral membrane regulatory protein SCO3033 32 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 21224409 Common - dehydrogenase SCO6080 3 None None None 21223590 Common - lyase SCO5222 10 None None None 21222530 Nonpathogen - integral membrane protein SCO4131 1 None None None 21222745 Nonpathogen - hypothetical protein SCO4354 2 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 32141148 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein SCO1579 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 21223008 Nonpathogen - hypothetical protein SCO4625 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 21223889 Common - secreted lyase SCO5534 12 None None None 21221870 Nonpathogen - small membrane protein SCO3445 1 None None None 21219589 Common - hypothetical protein SCO1074 179 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 21220648 Nonpathogen - transferase SCO2174 2 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21218899 Common - hypothetical protein SCO0355 14 COG3254 COG3254, Uncharacterized conserved protein Function unknown 21224875 Nonpathogen - hypothetical protein SCO6574 1 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 21224658 Common - secreted chitinase SCO6345 20 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 21223458 Common - actinorhodin polyketide beta-ketoacyl synthase alpha subunit SCO5087 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21218633 Nonpathogen - hypothetical protein SCO0058 1 None None None 21225700 Common - hypothetical protein SCO7430 32 COG1865 COG1865, Uncharacterized conserved protein Function unknown 21219991 Common nusB transcription antitermination protein NusB SCO1490 176 COG0781 NusB, Transcription termination factor Transcription 21221144 Common - hypothetical protein SCO2689 53 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21221589 Nonpathogen - hypothetical protein SCO3152 1 None None None 21221311 Nonpathogen - hypothetical protein SCO2861 1 None None None 21222732 Common - integrase SCO4340 61 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 21224971 Nonpathogen - DNA-binding protein SCO6675 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 21222888 Common - long-chain-fatty acid CoA ligase SCO4503 212 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 21219337 Common - iron-sulfur protein SCO0816 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 21225198 Nonpathogen - hypothetical protein SCO6908 1 None None None 21225697 Common - hypothetical protein SCO7427 54 COG1959 COG1959, Predicted transcriptional regulator Transcription 21220384 Common - transcriptional regulator SCO1897 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 21220641 Common - hypothetical protein SCO2167 10 None None None 21221147 Common - repetative protein SCO2692 51 COG2319 COG2319, FOG: WD40 repeat General function prediction only 21218902 Common - racemase SCO0358 91 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21222881 Common - acetyltransferase SCO4496 20 COG0456 RimI, Acetyltransferases General function prediction only 21223882 Common - hypothetical protein SCO5527 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 21222335 Common - hypothetical protein SCO3929 4 None None None 21222304 Nonpathogen - hypothetical protein SCO3897 1 None None None 21220132 Common - hypothetical protein SCO1636 25 COG2378 COG2378, Predicted transcriptional regulator Transcription 21222999 Nonpathogen - excisionase SCO4616 2 COG3311 AlpA, Predicted transcriptional regulator Transcription 21219818 Common - hypothetical protein SCO1311 15 COG2606 EbsC, Uncharacterized conserved protein Function unknown 21222644 Nonpathogen - hypothetical protein SCO4249 1 None None None 21223132 Nonpathogen - hypothetical protein SCO4753 1 None None None 21224218 Common - potassium uptake protein SCO5875 142 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 21223212 Common - gntR-family regulator SCO4836 137 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 32141282 Common - 1-deoxy-D-xylulose-5-phosphate synthase SCO6013 221 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 21220624 Common trpD anthranilate phosphoribosyltransferase SCO2147 219 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 21222629 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase SCO4234 185 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 21223427 Common - hypothetical protein SCO5054 15 None None None 21224230 Common - 3-oxoacyl-(acyl carrier protein) synthase III SCO5888 222 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 21224558 Nonpathogen - regulatory protein SCO6237 2 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220513 Common - hypothetical protein SCO2032 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 21219779 Common - 3-oxoacyl-(ACP) synthase III SCO1271 195 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 21218915 Common - secreted protein SCO0371 29 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 21224992 Common - 3-carboxy-cis,cis-muconate cycloisomerase SCO6698 137 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 21222255 Common - FtsW/RodA/SpoVE family cell cycle protein SCO3846 202 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 21223289 Nonpathogen - integral membrane protein SCO4915 1 None None None 21224927 Common - hypothetical protein SCO6630 5 None None None 21218978 Common rpmF 50S ribosomal protein L32 SCO0436 4 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 21225530 Common - hypothetical protein SCO7253 66 None None None 21225010 Nonpathogen - hypothetical protein SCO6716 1 None None None 21224371 Common - flavoprotein oxidoreductase SCO6039 203 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 21225713 Common - phosphoglucomutase SCO7443 219 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 21223825 Common - transmembrane transport protein SCO5468 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21223077 Common - integral membrane protein SCO4697 12 None None None 21225249 Common - glutamine synthetase SCO6962 221 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 21222542 Nonpathogen - hypothetical protein SCO4144 1 None None None 21224525 Common - glyoxylate carboligase SCO6201 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 21219114 Common - transporter protein SCO0581 140 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 21224917 Common - dehydrogenase SCO6619 230 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21220216 Nonpathogen - hypothetical protein SCO1722 6 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 21224281 Common - hydrolase SCO5943 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21220100 Common - transposase SCO1603 28 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219399 Common - hydrolase SCO0878 105 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21223904 Common - hydrolase SCO5549 77 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 21221748 Common - uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase SCO3317 184 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 21222319 Common - beta-lactamase SCO3912 131 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21222434 Common - integral membrane transport protein SCO4031 185 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224139 Common - kinase/phosphohydrolase SCO5794 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 21219221 Nonpathogen - membrane protein SCO0693 1 None None None 21222860 Common - cytochrome biogenesis related protein SCO4473 186 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 21221536 Common - secreted protein SCO3097 12 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 21225363 Common - phospholipase SCO7081 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 21225019 Common - hypothetical protein SCO6725 35 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 21219322 Common - TetR-family transcriptional regulatory protein SCO0800 67 COG1309 AcrR, Transcriptional regulator Transcription 21221318 Common - regulatory protein SCO2869 7 COG1396 HipB, Predicted transcriptional regulators Transcription 21221858 Nonpathogen - membrane protein SCO3431 1 None None None 21223921 Common - hypothetical protein SCO5565 46 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 21219301 Common - integral membrane protein SCO0778 3 None None None 21222126 Nonpathogen - hypothetical protein SCO3713 2 None None None 21219764 Nonpathogen - hypothetical protein 2SCG1803c SCO1256 1 None None None 21220776 Common - two-component sensor kinase SCO2307 113 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21224421 Common - hypothetical protein SCO6092 41 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 21220461 Common - AbaA-like protein SCO1978 6 None None None 21222983 Common - NADH dehydrogenase subunit NuoB2 SCO4600 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 21224705 Common - transposase SCO6393 82 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 21225516 Common - hypothetical protein SCO7239 24 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 21220312 Common - integral membrane protein SCO1823 20 COG3162 COG3162, Predicted membrane protein Function unknown 21224506 Common - dehydratase SCO6182 120 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 21223573 Common - hypothetical protein SCO5205 48 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 21221605 Common - protease SCO3168 40 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 21225430 Common - acetyltransferase SCO7150 9 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 21219079 Common - conserved hypothetical secreted protein SCO0544 16 COG5607 COG5607, Uncharacterized conserved protein Function unknown 21219176 Common - TetR-family transcriptional regulator SCO0646 9 COG1309 AcrR, Transcriptional regulator Transcription 21220466 Common - hypothetical protein SCO1983 28 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 32141100 Common - sugar-transport protein SCO0137 39 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 21225723 Nonpathogen - hypothetical protein SCO7454 4 COG1715 Mrr, Restriction endonuclease Defense mechanisms 21221645 Common - 2-dehydro-3-deoxyheptonate aldolase SCO3210 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 21225185 Common - hypothetical protein SCO6894 13 COG1733 COG1733, Predicted transcriptional regulators Transcription 21221221 Common - acetolactate synthase SCO2769 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 21222916 Nonpathogen - hypothetical protein SCO4532 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 21220639 Common - two component system response regulator SCO2165 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21224453 Nonpathogen - hypothetical protein SCO6126 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 32141204 Common - hypothetical protein SCO3444 68 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 21224513 Common - transferase SCO6189 51 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 21222144 Common - DEAD-box RNA helicase SCO3732 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 21220924 Common - hypothetical protein SCO2460 12 None None None 21225668 Common - hypothetical protein SCO7397 16 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 21219903 Common - ATP/GTP-binding protein SCO1399 32 COG2229 COG2229, Predicted GTPase General function prediction only 21223196 Nonpathogen - secreted protein SCO4819 1 None None None 21222003 Nonpathogen - integral membrane protein SCO3586 1 None None None 21221403 Common - bifunctional uroporphyrinogen-III synthetase/response regulator domain protein SCO2958 52 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 21220051 Common - rRNA methylase SCO1552 209 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 21225795 Common - regulatory protein SCO7530 140 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 21223319 Common - hypothetical protein SCO4946 10 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21222633 Common - guanyltransferase SCO4238 174 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 21219542 Common - transcriptional regulatory protein SCO1026 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 21221235 Common - aceytltranferase SCO2784 41 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21223168 Nonpathogen - integral membrane protein SCO4789 2 COG2259 COG2259, Predicted membrane protein Function unknown 21223922 Common - ATP-dependent DNA helicase SCO5566 212 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 21224469 Common - hypothetical protein SCO6143 51 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 21225913 Common - acetyltransferase SCO7652 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21221948 Nonpathogen - hypothetical protein SCO3527 1 None None None 21225179 Nonpathogen - hypothetical protein SCO6888 1 None None None 21222561 Nonpathogen - secreted protein SCO4163 2 None None None 21219466 Common - alpha-mannosidase SCO0948 51 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 21219153 Common - hypothetical protein SCO0621 48 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 21219628 Common - uracil-DNA glycosylase SCO1114 130 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 21224788 Common - hypothetical protein SCO6484 104 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 32141134 Common - xylulose kinase SCO1170 171 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 21225800 Nonpathogen - lipoprotein SCO7535 1 None None None 21220605 Nonpathogen - hypothetical protein SCO2127 1 None None None 21218781 Nonpathogen - hypothetical protein SCO0228 1 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21220812 Common - integral membrane transport protein SCO2344 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224671 Common - hypothetical protein SCO6358 11 COG3682 COG3682, Predicted transcriptional regulator Transcription 21225715 Nonpathogen - regulator SCO7446 1 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21218870 Nonpathogen - hypothetical protein SCO0323 1 None None None 32141193 Common - hypothetical protein SCO3150 30 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 21222765 Common - marR-family regulatory protein SCO4375 73 COG1846 MarR, Transcriptional regulators Transcription 21220593 Common - 2-dehydro-3-deoxyphosphoheptonate aldolase SCO2115 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 21220022 Common - hypothetical protein SCO1522 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 21226030 Common - hydrolase SCO7777 56 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221260 Nonpathogen - hypothetical protein SCO2809 1 COG1715 Mrr, Restriction endonuclease Defense mechanisms 21225900 Common - marR-family regulatory protein SCO7639 29 COG1846 MarR, Transcriptional regulators Transcription 21221821 Common - integral membrane protein SCO3393 33 COG3402 COG3402, Uncharacterized conserved protein Function unknown 21225140 Common - hypothetical protein SCO6848 8 None None None 21219530 Common - mut-like protein SCO1013 66 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21223837 Common - oligopeptide ABC transporter ATP-binding protein SCO5480 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 21223974 Nonpathogen - hypothetical protein SCO5619 1 None None None 21221138 Common - single-strand DNA-binding protein SCO2683 19 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 21222155 Common - hypothetical protein SCO3743 26 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 32141113 Common - secreted chitinase SCO0482 21 COG3179 COG3179, Predicted chitinase General function prediction only 32141171 Nonpathogen - hypothetical protein SCO2495 10 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 21219404 Common - probable oxidoreductase SCO0884 228 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 21222462 Common - transcriptional regulator SCO4059 66 COG1777 COG1777, Predicted transcriptional regulators Transcription 21219069 Common - beta-hexosaminidase (secreted protein) SCO0534 51 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 21225514 Nonpathogen - secreted protein SCO7237 1 None None None 21219580 Common - sugar transport sugar binding protein SCO1065 56 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21220850 Common - secreted protein SCO2383 18 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 21220258 Common - glycohydrolase SCO1766 18 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21222484 Common - secreted peptidase SCO4082 92 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21221169 Nonpathogen - secreted protein SCO2714 5 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 21222955 Common - NADH dehydrogenase subunit K SCO4572 157 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 21224807 Common - hypothetical protein SCO6504 16 COG5637 COG5637, Predicted integral membrane protein Function unknown 21223718 Common - hypothetical protein SCO5358 63 COG1316 LytR, Transcriptional regulator Transcription 21224905 Common - hypothetical protein SCO6607 12 None None None 21223651 Common - ATP-dependent protease SCO5285 203 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 21222191 Common - sugar hydrolase SCO3780 145 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21224157 Nonpathogen - hypothetical protein SCO5813 1 None None None 21222838 Common - tetR-family transcriptional regulator SCO4450 28 COG1309 AcrR, Transcriptional regulator Transcription 21219389 Nonpathogen - regulatory protein SCO0868 1 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21223830 Common - ATP/GTP binding protein SCO5473 5 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 21221828 Common - hydroxymethyldihydropteridine pyrophosphokinase SCO3401 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 21223354 Nonpathogen - bifunctional protein SCO4981 1 COG4282 SMI1, Protein involved in beta-1,3-glucan synthesis Carbohydrate transport and metabolism 21219535 Common - glutamate racemase SCO1018 69 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 21225881 Common - anti sigma factor antagonist SCO7619 22 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21225611 Nonpathogen - hypothetical protein SCO7336 1 None None None 21222670 Common - tellurium resistance protein SCO4277 29 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21220037 Common - transport system membrane protein SCO1537 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21222137 Common - hypothetical protein SCO3725 5 None None None 21222311 Common - hypothetical protein SCO3904 31 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 21223430 Common - amino acid permease SCO5057 93 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21223583 Common - hypothetical protein SCO5215 37 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 21222095 Common - delta fatty acid desaturase SCO3682 45 COG3239 DesA, Fatty acid desaturase Lipid metabolism 161353680 Common rpmB 50S ribosomal protein L28 SCO3429 85 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 21225309 Common - acetyltransferase SCO7024 7 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21218583 Nonpathogen - hypothetical protein SCO0001 1 None None None 21224006 Common - hypothetical protein SCO5655 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 21224054 Common - hypothetical protein SCO5705 46 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 21224199 Common - DNA-binding protein SCO5855 19 None None None 21225707 Common - benzoylformate decarboxylase SCO7437 219 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 21225784 Common - tetR-family transcriptional regulatory protein SCO7518 24 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 21225235 Common - hypothetical protein SCO6948 89 COG1720 COG1720, Uncharacterized conserved protein Function unknown 21225748 Common - hypothetical protein SCO7480 6 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21220275 Nonpathogen - hypothetical protein SCO1783 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21219525 Common - hypothetical protein SCO1008 21 COG0640 ArsR, Predicted transcriptional regulators Transcription 21219446 Common - lysR-family transcriptional regulator SCO0927 171 COG0583 LysR, Transcriptional regulator Transcription 21220082 Common - hypothetical protein SCO1585 36 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 32141209 Common - transpeptidase SCO3580 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 21224211 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase SCO5868 174 COG0756 Dut, dUTPase Nucleotide transport and metabolism 21222679 Common - solute-binding protein (secreted protein) SCO4286 89 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21224862 Common - respiratory chain oxidoreductase SCO6560 162 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 21221363 Common clpS ATP-dependent Clp protease adaptor protein ClpS SCO2916 19 COG2127 COG2127, Uncharacterized conserved protein Function unknown 21221696 Nonpathogen - hypothetical protein SCO3263 1 None None None 21224987 Nonpathogen - hypothetical protein SCO6693 4 None None None 21224921 Common - ATP/GTP binding protein SCO6623 20 COG3410 COG3410, Uncharacterized conserved protein Function unknown 21218852 Nonpathogen - secreted protein SCO0303 1 None None None 21223654 Common - hypothetical protein SCO5288 7 None None None 21222112 Common - transcriptional regulator SCO3699 116 COG0640 ArsR, Predicted transcriptional regulators Transcription 21225957 Common - secreted hydrolase SCO7697 19 COG4247 Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) Lipid metabolism 21223956 Common - hypothetical protein SCO5601 17 None None None 21221206 Common - hypothetical protein SCO2754 18 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21225952 Nonpathogen - hypothetical protein SCO7692 1 None None None 21218859 Common - ligase SCO0311 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21225105 Common - ArsR-family transcriptional regulator SCO6812 145 COG0640 ArsR, Predicted transcriptional regulators Transcription 21219801 Common - cystathionine gamma-synthase SCO1294 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 21223831 Nonpathogen - hypothetical protein SCO5474 2 None None None 21219508 Common - hypothetical protein SCO0991 16 COG4542 PduX, Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase Secondary metabolites biosynthesis, transport, and catabolism 21219145 Nonpathogen - secreted protein SCO0612 1 None None None 21220367 Common - secreted pectinesterase SCO1879 20 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 21222834 Common - integral membrane protein SCO4446 4 None None None 21221916 Common - sugar kinase SCO3494 171 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21224587 Nonpathogen - ScbA protein SCO6266 4 None None None 21221579 Nonpathogen - hypothetical protein SCO3141 1 None None None 21224319 Common - regulator SCO5982 29 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 32141120 Common - oxidoreductase SCO0691 117 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 21219610 Nonpathogen - hypothetical protein 2SCG411 SCO1095 1 None None None 21224028 Common - aldehyde dehydrogenase SCO5679 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21226015 Nonpathogen - hypothetical protein SCO7761 1 None None None 21220344 Common - precorrin-6Y C5,15-methyltransferase SCO1856 108 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 21221957 Common - DNA-binding protein SCO3537 41 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 21220488 Nonpathogen - hypothetical protein SCO2006 1 None None None 21224938 Common - hypothetical protein SCO6641 47 None None None 21225156 Common - regulatory protein SCO6865 71 COG0714 COG0714, MoxR-like ATPases General function prediction only 21220163 Common - ion transport protein SCO1667 165 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 21219880 Nonpathogen - hypothetical protein SCO1375 3 None None None 21222299 Common - RNA polymerase sigma factor SigM SCO3892 170 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21224830 Common - integral membrane transport protein SCO6528 106 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 32141275 Common - SuhB protein SCO5860 194 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 21220745 Common - membrane protein SCO2276 39 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 21222293 Common - partitioning or sporulation protein SCO3886 202 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 21225508 Common - two-component system sensor kinase SCO7231 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21225232 Nonpathogen - hypothetical protein SCO6945 1 None None None 21222690 Common - oxidoreduxtase SCO4297 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 32141293 Common - DNA-binding protein SCO6236 6 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 21221080 Common - hypothetical protein SCO2623 13 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 21221894 Nonpathogen - transposase SCO3470 4 None None None 21219473 Nonpathogen - hypothetical protein SCO0955 1 None None None 21222018 Common - transmembrane transport protein SCO3602 23 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 21225984 Nonpathogen - hypothetical protein SCO7725 1 None None None 21221758 Nonpathogen - hypothetical protein SCO3327 1 None None None 21223638 Common - hypothetical protein SCO5271 5 None None None 21225824 Common - MutT-family protein SCO7560 2 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21222344 Common - hypothetical protein SCO3939 26 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21222942 Common - electron transfer oxidoreductase SCO4559 135 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21219964 Common - hypothetical protein SCO1462 2 None None None 21219438 Common - hypothetical protein SCO0919 8 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 21223265 Nonpathogen - secreted protein SCO4891 1 None None None 21224209 Common - hypothetical protein SCO5866 12 None None None 21220062 Common - acetyltransferase SCO1563 28 COG0456 RimI, Acetyltransferases General function prediction only 21221940 Nonpathogen - hypothetical protein SCO3519 1 None None None 21221426 Common - glycosyl transferase SCO2982 129 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 21220122 Common - cytochrome P450 SCO1626 63 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21221203 Common - hypothetical protein SCO2751 21 None None None 21224668 Common - integral membrane protein SCO6355 5 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21221054 Common rpmA 50S ribosomal protein L27 SCO2596 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 21220128 Common - integral membrane protein SCI4115c SCO1632 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 21223127 Nonpathogen - hypothetical protein SCO4748 1 None None None 21223720 Common prfA peptide chain release factor 1 SCO5360 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 21219415 Common - RNA polymerase principal sigma factor HrdC SCO0895 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 21221127 Common - globin SCO2671 69 COG2346 COG2346, Truncated hemoglobins General function prediction only 21221077 Common tig trigger factor SCO2620 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 21220964 Common - chitinase precursor SCO2503 22 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 21224574 Common - two-component sensor kinase SCO6253 93 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 32141260 Common - hypothetical protein SCO5332 7 None None None 21224324 Nonpathogen - hypothetical protein SCO5987 3 None None None 21219689 Common - hypothetical protein SCO1178 2 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 21218629 Nonpathogen - hypothetical protein SCO0050 1 None None None 21225909 Common - two-component system response regulator SCO7648 176 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21222973 Common - hypothetical protein SCO4590 14 None None None 21224150 Common - vitamin B12-dependent ribonucleotide reductase SCO5805 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 21223816 Common - lipoprotein SCO5458 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 21221783 Nonpathogen - hypothetical proline-rich protein SCO3354 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21219103 Common rpmJ 50S ribosomal protein L36 SCO0569 49 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 21219597 Common - electron transfer flavoprotein, beta subunit SCO1082 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 21224244 Common - probable export protein SCO5905 51 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225646 Common - hypothetical protein SCO7372 15 COG2259 COG2259, Predicted membrane protein Function unknown 21223707 Nonpathogen - hypothetical protein SCO5346 1 None None None 21225050 Common - ABC transporter membrane component SCO6757 71 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 21220481 Common - hypothetical protein SCO1999 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21219921 Common - integral membrane protein SCO1418 28 COG2364 COG2364, Predicted membrane protein Function unknown 21220559 Common - hypothetical protein SCO2079 53 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 21220398 Common - integral membrane protein SCO1911 10 None None None 21222993 Common - hypothetical protein SCO4610 41 COG3304 COG3304, Predicted membrane protein Function unknown 21223202 Nonpathogen - integral membrane protein SCO4825 1 None None None 21221794 Common - hypothetical protein SCO3365 6 None None None 21224823 Common - secreted protein SCO6521 4 None None None 21225585 Common - membrane transport protein SCO7309 133 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 21220071 Common - oxidoreductase (membrane protein) SCO1573 139 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 21223535 Common - helicase SCO5166 231 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 21225937 Common - secreted solute-binding protein SCO7677 169 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21224108 Common - AraC family transcriptional regulator SCO5762 56 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21221580 Nonpathogen - hypothetical protein SCO3142 1 None None None 21220096 Common rpmI 50S ribosomal protein L35 SCO1599 127 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 21223994 Nonpathogen - hypothetical protein SCO5643 1 None None None 32141335 Common - oxidoreductase SCO7525 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 21226009 Common - integral membrane protein SCO7752 10 None None None 21224398 Common - hypothetical protein SCO6068 15 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21221819 Common - hypothetical protein SCO3391 16 COG1565 COG1565, Uncharacterized conserved protein Function unknown 21221520 Common - acetyl-CoA acetyltransferase SCO3079 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21223147 Common - two-component regulator SCO4768 195 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221768 Common - integral membrane protein SCO3338 109 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21220552 Common - hypothetical protein SCO2072 33 COG2153 ElaA, Predicted acyltransferase General function prediction only 21223763 Common - probable two-component system response regulator SCO5403 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21224212 Common - hypothetical protein SCO5869 19 None None None 21222692 Nonpathogen - integral membrane protein SCO4299 1 None None None 21225369 Common - oxidoreductase SCO7087 177 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21224063 Common - peptide transport system secreted peptide binding protein SCO5716 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21220818 Common - integral membrane protein SCO2350 36 COG2259 COG2259, Predicted membrane protein Function unknown 21221407 Common - bi-functional transferase/deacetylase SCO2962 221 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21225360 Common - integral membrane protein SCO7077 49 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225828 Common - oligopeptide ABC transporter integral membrane protein SCO7564 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21218674 Common - DNA-binding protein SCO0110 41 None None None 21222921 Nonpathogen - hypothetical protein 2SCD408 SCO4537 1 None None None 21221791 Common - hypothetical protein SCO3362 10 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 21225752 Nonpathogen - hypothetical protein SCO7484 1 None None None 21219108 Common - IclR-family regulatory protein SCO0574 115 COG1414 IclR, Transcriptional regulator Transcription 21221581 Nonpathogen - hypothetical protein SCO3143 1 None None None 21223300 Common - propionyl-CoA carboxylase complex B subunit SCO4926 213 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 21221956 Nonpathogen - hypothetical protein SCO3535 3 None None None 21219183 Nonpathogen - hypothetical protein SCO0653 1 None None None 21219670 Common - ATP/GTP binding protein SCO1157 29 COG2229 COG2229, Predicted GTPase General function prediction only 21219179 Nonpathogen - gas vesicle synthesis protein SCO0649 7 None None None 21222290 Common - putative inner membrane protein translocase component YidC SCO3883 211 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 21222218 Common - hypothetical protein SCO3808 8 None None None 21223920 Common rpmB 50S ribosomal protein L28 SCO5564 71 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 21219437 Common - excinuclease ABC subunit A SCO0918 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 21225839 Common - secreted hydrolase SCO7575 47 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 21224652 Common - 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase SCO6339 156 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 21225490 Common - hypothetical protein SCO7213 36 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 21221264 Common - methyltransferase SCO2814 183 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221485 Common - transcriptional regulator SCO3042 64 COG1316 LytR, Transcriptional regulator Transcription 21223031 Common rplA 50S ribosomal protein L1 SCO4649 219 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 21220775 Common - ABC transporter integral membrane protein SCO2306 17 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21224427 Common - sulfate adenylyltransferase subunit 2 SCO6098 133 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 21221201 Common - carbohydrate transport protein SCO2749 46 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 21219790 Common - oxidoreductase SCO1282 105 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 21223578 Common - molecular chaperone SCO5210 97 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 21221204 Common - oxidoreductase SCO2752 48 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21224165 Common - serine protease SCO5821 27 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 21219621 Common - lipoprotein SCO1106 37 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 21225902 Common - dehydrogenase SCO7641 127 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 21221239 Nonpathogen - hypothetical protein SCO2788 2 None None None 21226082 Nonpathogen - hypothetical protein SCO7833 1 None None None 21221594 Common - penicillin-binding protein (secreted protein) SCO3157 66 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21220616 Common - integral membrane protein SCO2139 110 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 21220158 Common - hypothetical protein SCO1662 22 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 21219904 Common - hypothetical protein SCO1400 6 None None None 32141343 Nonpathogen - hypothetical protein SCO7804 4 None None None 21222909 Nonpathogen - hypothetical protein SCO4524 2 None None None 21219284 Common - methyltransferase SCO0760 13 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 21222347 Nonpathogen - hypothetical protein SCO3942 1 None None None 21224208 Common - hypothetical protein SCO5865 3 None None None 21222248 Common - hypothetical protein SCO3839 124 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 21223536 Common - hypothetical protein SCO5167 13 None None None 21225067 Common - hypothetical protein SCO6774 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21218940 Nonpathogen - integral membrane protein SCO0397 5 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 21219115 Common - transcriptional regulator SCO0582 144 COG2186 FadR, Transcriptional regulators Transcription 21223009 Nonpathogen - hypothetical protein SCO4626 1 None None None 21221930 Common - hypothetical protein SCO3509 16 COG3586 COG3586, Uncharacterized conserved protein Function unknown 21225989 Common - hypothetical protein SCO7730 46 COG2388 COG2388, Predicted acetyltransferase General function prediction only 21222000 Common - integral membrane regulator SCO3583 2 None None None 21220335 Nonpathogen - hypothetical protein SCO1846 1 None None None 21222041 Common - RNA polymerase sigma factor SCO3626 54 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225799 Common - two component system histidine kinase SCO7534 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21222729 Common - integral membrane efflux protein SCO4337 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224761 Common - ABC transporter ATP-binding protein SCO6455 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21221671 Common - hypothetical protein SCO3238 10 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21225012 Common - dimethylarginine dimethylaminohydrolase SCO6718 30 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 21224313 Common - ornithine carbamoyltransferase SCO5976 236 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 32141117 Common - putative phosphoketolase SCO0617 66 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 21224903 Common - transmembrane sugar transport protein SCO6603 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21222715 Common - hydrolase SCO4323 7 COG0546 Gph, Predicted phosphatases General function prediction only 21224627 Common - lysR-family transcriptional regulator SCO6309 96 COG0583 LysR, Transcriptional regulator Transcription 21224201 Common - FAD-dependent oxidoreductase SCO5857 40 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21219925 Nonpathogen - membrane protein SCO1422 2 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 21224010 Nonpathogen - integral membrane protein SCO5659 3 None None None 21221976 Common - septum site determining protein SCO3557 12 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 21224326 Nonpathogen - integral membrane protein SCO5989 1 None None None 21226007 Common - hypothetical protein SCO7750 2 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21218634 Common - zinc-binding oxidoreductase SCO0059 136 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21220377 Common - transcriptional regulator SCO1890 113 COG1802 GntR, Transcriptional regulators Transcription 21223802 Common - alpha-amylase SCO5443 78 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21219199 Common - TetR-family transcriptional regulator SCO0669 9 COG1309 AcrR, Transcriptional regulator Transcription 21219172 Common - hypothetical protein SCO0642 26 None None None 21224196 Common - tagatose-bisphosphate aldolase SCO5852 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 21220951 Common - nitrite reductase small subunit NirC SCO2488 44 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 21221949 Common - hypothetical protein SCO3528 27 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 21222303 Common - RNA nucleotidyltransferase SCO3896 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 21225791 Common - chloramphenicol resistance protein SCO7526 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21223125 Common - lipase SCO4746 107 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21222630 Common cysS cysteinyl-tRNA synthetase SCO4235 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21224359 Common - acetyl-coa acetyltransferase (thiolase) SCO6027 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21222390 Common - GntR-family transcriptional regulator SCO3986 109 COG2188 PhnF, Transcriptional regulators Transcription 21218739 Nonpathogen - hypothetical protein SCO0182 1 None None None 21221279 Common - probable amino acid ABC transporter protein, integral membrane component SCO2829 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 21225102 Common - integral membrane transport protein SCO6809 34 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220629 Common - response regulator SCO2152 11 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21218713 Common - hypothetical protein SCO0156 2 None None None 21218732 Nonpathogen - hypothetical protein SCO0175 1 None None None 21220316 Common - DNA polymerase III subunit epsilon SCO1827 183 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 21218724 Common - hypothetical protein SCO0167 48 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21221941 Nonpathogen - hypothetical protein SCO3520 1 None None None 21223656 Common - hypothetical protein SCO5291 9 None None None 21222089 Nonpathogen - integral membrane protein SCO3676 1 None None None 32141235 Common purU formyltetrahydrofolate deformylase SCO4403 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 21222990 Common - NADH dehydrogenase subunit NuoM2 SCO4607 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 21220370 Common - secreted sugar-binding protein SCO1882 114 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21222365 Common - hypothetical protein SCO3960 111 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 21222399 Nonpathogen - excisionase SCO3996 3 None None None 21224797 Nonpathogen - hypothetical protein SCO6494 1 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 21220404 Common - hypothetical protein SCO1917 31 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 21222301 Common - transmembrane protein SCO3894 185 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 21222241 Common - transcriptional regulator SCO3832 60 COG1522 Lrp, Transcriptional regulators Transcription 21222619 Common - AraC-family transcriptional regulator SCO4223 80 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 21223174 Common - NLP/P60 family secreted protein SCO4796 143 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21223822 Nonpathogen - hypothetical protein SCO5464 1 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 21222339 Common - regulatory protein SCO3933 3 None None None 21219884 Common - hypothetical protein SCO1379 8 None None None 21223587 Common - lipoprotein SCO5219 15 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 21225939 Common - transport system integral membrane protein SCO7679 25 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21221822 Nonpathogen - secreted protein SCO3395 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 21222981 Common - two-component system sensor kinase SCO4598 123 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223207 Common - glycine betaine ABC transport system ATP-binding protein SCO4830 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 21220784 Common - hypothetical protein SCO2316 12 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 21219135 Common - hypothetical protein SCO0602 37 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 21224566 Nonpathogen - hypothetical protein SCO6245 1 None None None 21224625 Common - cyclase SCIF309c SCO6307 33 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 21225698 Common - flavohemoprotein SCO7428 133 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 21221887 Nonpathogen - hypothetical protein SCO3462 2 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 21222760 Common - transposase SCO4370 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21224581 Common - sugar kinase SCO6260 166 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21224666 Common - two-component sensor SCO6353 173 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21220935 Common - integral membrane protein SCO2472 73 COG2949 SanA, Uncharacterized membrane protein Function unknown 21219407 Common - TetR-family transcriptional regulator SCO0887 11 COG1309 AcrR, Transcriptional regulator Transcription 21221227 Common - acetyl/propionyl CoA carboxylase, beta subunit SCO2776 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 21220692 Nonpathogen - hypothetical protein SCO2220 1 None None None 21221166 Common - glycosyl transferase SCO2711 98 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21222150 Nonpathogen - integral membrane protein SCO3738 1 None None None 21225518 Common - oxidoreductase SCO7241 39 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21220065 Common - transmembrane-transport protein SCO1567 138 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21219151 Nonpathogen - hypothetical protein SCO0619 1 COG0730 COG0730, Predicted permeases General function prediction only 21225930 Common - hypothetical protein SCO7670 14 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 21222007 Nonpathogen - small membrane protein SCO3591 1 None None None 21224187 Common - hypothetical protein SCO5843 8 None None None 21221232 Common - hypothetical protein SCO2781 62 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 21225912 Common - tetR-family transcriptional regulator SCO7651 22 COG1309 AcrR, Transcriptional regulator Transcription 21218868 Common - hypothetical protein SCO0320 18 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21224731 Common - two-component system sensor protein SCO6424 136 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21224023 Common - secreted chitinase SCO5673 22 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 21220021 Common - hypothetical protein SCO1521 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 21225532 Common - hypothetical protein SCO7255 19 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 21223001 Nonpathogen - hypothetical protein SCO4618 1 None None None 21221863 Nonpathogen - integral membrane protein SCO3437 1 None None None 21220175 Common - gluconokinase SCO1679 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 21220586 Common - hypothetical protein SCO2108 67 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 21220394 Nonpathogen - hypothetical protein SCO1907 2 None None None 21219531 Common - transferase SCO1014 152 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 21220529 Common - hisF, cyclase SCO2048 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 21226033 Common - transcriptional regulator SCO7780 12 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21226016 Nonpathogen - hypothetical protein SCO7762 1 None None None 21220446 Common - 3-dehydroquinate dehydratase SCO1961 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 21225243 Common - putative monovalent cation/H+ antiporter subunit D SCO6956 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 21219032 Common - iron-siderophore binding lipoprotein SCO0494 64 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 32141219 Common - chromosomal replication initiator protein SCO3879 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 21220053 Common - nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase SCO1554 147 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 21222949 Common - NADH dehydrogenase subunit E SCO4566 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 21219716 Common - polyketide synthase SCO1206 44 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 21222435 Common - marR regulatory protein SCO4032 37 COG1846 MarR, Transcriptional regulators Transcription 21225956 Common - marR-family transcriptional regulator SCO7696 48 COG1846 MarR, Transcriptional regulators Transcription 21218655 Common - ribosylglycohydrolase (secreted protein) SCO0086 21 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21219001 Common - hypothetical protein SCO0460 24 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21224352 Common - transcriptional regulator SCO6020 63 COG1316 LytR, Transcriptional regulator Transcription 21224704 Common - transposase SCO6392 21 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 32141125 Common - ABC transporter ATP-binding protein SCO0811 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 21222720 Nonpathogen - lipoprotein SCO4328 1 None None None 21225527 Common - hypothetical protein SCO7250 46 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 21222952 Common - NADH dehydrogenase subunit H SCO4569 190 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 21222672 Common - acetyltransferase SCO4279 8 None None None 21225364 Common - hypothetical protein SCO7082 3 None None None 21223648 Common - two-component system sensor kinase SCO5282 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 21224002 Common - hypothetical protein SCO5651 28 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 21223610 Common - RNA polymerase sigma factor SCO5243 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21220271 Common - hypothetical protein SCO1779 37 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21223999 Common - ABC transporter ATP-binding protein SCO5648 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 21224520 Common - acyl-CoA synthetase SCO6196 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222340 Nonpathogen - hypothetical protein SCO3935 1 None None None 21224775 Common - citratelyase SCO6471 117 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 21221547 Nonpathogen - hypothetical protein SCO3108 1 None None None 21221575 Common - UDP-glucose 4-epimerase SCO3137 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 21219052 Nonpathogen - hypothetical protein SCO0517 2 None None None 21224479 Nonpathogen - regulatory protein SCO6153 5 COG1378 COG1378, Predicted transcriptional regulators Transcription 21220289 Common - ABC transporter ATP-binding subunit SCO1798 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 21223697 Common - mutT-like protein SCO5336 117 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21226043 Common - secreted oxidoreductase SCO7791a 56 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21224395 Common - secreted substrate-binding protein SCO6065 89 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 21220086 Common - hypothetical protein SCO1589 7 None None None 21223352 Common - phosphoenolpyruvate carboxykinase SCO4979 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 21222314 Common - single-strand DNA-binding protein SCO3907 183 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 21222104 Common - regulatory protein SCO3691 91 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21223559 Common - DNA-binding protein SCO5190 15 None None None 21222456 Common - transport integral membrane protein SCO4053 37 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 21223753 Common - ABC transporter ATP-binding subunit SCO5393 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 32141133 Common - helicase SCO1167 145 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 21221590 Common - hypothetical protein SCO3153 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 32141194 Common - penicillin acylase SCO3184 74 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 21222145 Nonpathogen - hypothetical protein SCO3733 1 None None None 21221073 Common valS valyl-tRNA synthetase SCO2615 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21225649 Common - hypothetical protein SCO7376 23 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 21222487 Common - lipoprotein SCO4085 8 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 21219640 Common - hypothetical protein SCO1126 19 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 21224033 Common - two-component system response regulator SCO5684 198 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221914 Nonpathogen - hypothetical protein SCO3492 1 None None None 21224043 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase SCO5694 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 21221921 Nonpathogen - integral membrane protein SCO3499 1 None None None 21222139 Common - stress response protein SCO3727 26 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21220467 Common - hydrolase SCO1984 158 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 21222635 Common - ABC transporter ATP-binding protein SCO4240 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 21220608 Common - long chain fatty acid CoA ligase SCO2131 214 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 21220084 Common - transcriptional regulator SCO1587 183 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 21224931 Nonpathogen - hypothetical protein SCO6634 1 None None None 21223716 Common - threonine synthase SCO5355 201 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 21220847 Common - hypothetical protein SCO2380 32 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21220968 Common - metal transport ABC transporter SCO2507 193 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 21223254 Common - transferase SCO4880 119 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 21220855 Common - 3-oxoacyl-(acyl carrier protein) synthase III SCO2388 227 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 21221296 Common - transcriptional regulatory protein SCO2846 40 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21223269 Common - RNA polymerase factor sigma-70 SCO4895 163 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21221397 Common - helicase protein SCO2952 32 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 21223854 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C SCO5498 132 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 21225980 Common - hypothetical protein SCO7721 9 None None None 21222752 Nonpathogen - integral membrane protein SCO4361 2 None None None 21223456 Common - actinorhodin cluster activator protein SCO5085 16 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21223114 Common rpsI 30S ribosomal protein S9 SCO4735 216 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 21224360 Common - ribonuclease SCO6028 112 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 21226045 Nonpathogen - hypothetical protein SCO7793 1 None None None 21218919 Common - transcriptional regulator SCO0376 51 COG1396 HipB, Predicted transcriptional regulators Transcription 21223828 Common - glycine cleavage system H protein SCO5471 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 21223746 Nonpathogen - anti-sigma factor antagonist SCO5386 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21219761 Common - integral membrane protein SCO1252 213 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21221857 Common rpsN 30S ribosomal protein S14 SCO3430 189 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 21225193 Nonpathogen - hypothetical protein SCO6903 1 None None None 32141336 Common - sulfatase SCO7547 92 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 21221829 Common - secreted protein SCO3402 4 None None None 21223811 Common - integral membrane protein SCO5453 7 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21225821 Common - sugar transport integral membrane protein SCO7557 157 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21219411 Common - DNA-binding protein SCO0891 41 COG1396 HipB, Predicted transcriptional regulators Transcription 21222110 Common - oxidoreductase SCO3697 169 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21218912 Common - transposase SCO0368 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21225008 Common - hydroxylase SCO6714 33 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21223601 Common - sugar transporter integral membrane protein SCO5233 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21221180 Common - methylmalonic acid semialdehyde dehydrogenase SCO2726 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21220807 Nonpathogen - hypothetical protein SCO2339 1 None None None 21222464 Nonpathogen - hypothetical protein 2SCD6027c SCO4061 1 None None None 21222039 Nonpathogen - hypothetical protein SCO3624 2 None None None 21219398 Common - transcriptional regulatory protein SCO0877 57 COG3899 COG3899, Predicted ATPase General function prediction only 21222792 Nonpathogen - hypothetical protein SCO4402 1 None None None 21225060 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase SCO6767 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 21224145 Common - hypothetical protein SCO5800 46 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 21224151 Common - hypothetical protein SCO5806 10 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21220871 Common - sugar-binding receptor SCO2404 103 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 21225022 Nonpathogen - hypothetical protein SCO6728 1 None None None 21225111 Common - phosphoglyceromutase SCO6818 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 21221255 Nonpathogen - hypothetical protein SCO2804 1 None None None 21219267 Nonpathogen - secreted protein SCO0743 1 None None None 21222197 Nonpathogen - integral membrane protein SCO3786 1 None None None 21220238 Common - two-component system sensor kinase SCO1744 118 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223840 Common - transcriptional regulator SCO5483 36 COG1309 AcrR, Transcriptional regulator Transcription 32141291 Common - uricase SCO6211 14 COG3648 COG3648, Uricase (urate oxidase) Secondary metabolites biosynthesis, transport, and catabolism 21218803 Common - transcriptional regulator SCO0250 29 COG1309 AcrR, Transcriptional regulator Transcription 21222596 Common - hypothetical protein SCO4200 11 None None None 21223102 Common secY preprotein translocase subunit SecY SCO4722 231 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 21222087 Nonpathogen - sensor kinase SCO3674 3 None None None 21220520 Common trpC indole-3-glycerol-phosphate synthase SCO2039 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 21219996 Common - shikimate kinase I SCO1495 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 21221643 Common - secreted protein SCO3208 5 None None None 21225317 Common - hypothetical protein SCO7032 39 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 21221814 Nonpathogen - hypothetical protein SCO3386 1 None None None 21219334 Common - short chain dehydrogenase SCO0813 225 COG3347 COG3347, Uncharacterized conserved protein Function unknown 21220613 Common - secreted protein SCO2136 133 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21224158 Nonpathogen - hypothetical protein SCO5814 1 None None None 21224261 Common - short chain dehydrogenase SCO5922 57 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21224397 Common - hypothetical protein SCO6067 6 None None None 21220408 Common - ABC transporter ATP-binding subunit SCO1922 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 21220276 Common - hypothetical protein SCO1784 5 None None None 21225901 Common - lysR-family transcriptional regulator SCO7640 164 COG0583 LysR, Transcriptional regulator Transcription 21222012 Common - D-alanine:D-alanine dipeptidase SCO3596 43 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 21221252 Common - two component system response regulator SCO2801 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21218796 Nonpathogen - hypothetical protein SCO0243 1 None None None 21220635 Common - kinase SCO2158 105 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21219428 Common - hypothetical protein SCO0908 11 None None None 21220063 Nonpathogen - RNA polymerase sigma factor SCO1564 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21218851 Common - tetR-family transcriptional regulator SCO0302 18 None None None 21221542 Nonpathogen - integral membrane protein SCO3103 1 None None None 21219886 Common - hypothetical protein SCO1382 79 COG1259 COG1259, Uncharacterized conserved protein Function unknown 21224410 Common - alpha amylase SCO6081 104 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 21223885 Common - hypothetical protein SCO5530 4 COG4371 COG4371, Predicted membrane protein Function unknown 21223433 Common - translation-associated GTPase SCO5061 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 21219709 Common - acyl-CoA dehydrogenase SCO1198 141 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21219900 Common - D-alanyl-D-alanine dipeptidase (putative secreted protein) SCO1396 43 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 21220030 Common - hypothetical protein SCO1530 109 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 21222125 Common - hydrolase SCO3712 115 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21219872 Common - ABC transport system ATP-binding protein SCO1367 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21219616 Common - integral membrane protein SCO1101 14 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 21222647 Common - hypothetical protein SCO4252 18 None None None 21221849 Nonpathogen - hypothetical protein SCO3422 1 None None None 21220926 Common - ABC transporter SCO2463 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21220427 Common pgi glucose-6-phosphate isomerase SCO1942 180 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 21222615 Common - hydrolase (dienelactone hydrolase family) SCO4219 97 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21225048 Common - transferase SCO6755 9 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 21225478 Common - hypothetical protein SCO7200 4 None None None 21225708 Common - LysR-family transcriptional regulatory protein SCO7438 172 COG0583 LysR, Transcriptional regulator Transcription 21224440 Common - oligopeptide ABC transporter ATP-binding protein SCO6111 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 21222883 Common - proton transport protein SCO4498 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 21225889 Common - hypothetical protein SCO7627 30 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 21222508 Common - integral membrane protein SCO4107 78 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225435 Common - hypothetical protein SCO7155 14 None None None 21221316 Nonpathogen - hypothetical protein SCO2867 2 None None None 21223087 Common rplV 50S ribosomal protein L22 SCO4707 219 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 21219675 Common - methyltransferase SCO1162 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21218777 Nonpathogen - hypothetical protein SCO0224 1 None None None 21222545 Nonpathogen - integral membrane protein SCO4147 1 None None None 21225409 Common - hypothetical protein SCO7127 15 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21224690 Common - hypothetical protein SCO6378 11 None None None 21218959 Common - hypothetical protein SCO0417 8 None None None 21219811 Common - hypothetical protein SCO1304 121 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 21225238 Common - hypothetical protein SCO6951 6 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 21218894 Common - hypothetical protein SCO0350 43 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 21218986 Nonpathogen - integral membrane protein SCO0444 1 None None None 21219455 Common - oligosaccharide deacetylase SCO0936 121 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21224009 Common - polyamine-binding lipoprotein SCO5658 121 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 21222259 Common - integral membrane protein SCO3850 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 21218918 Common - ABC transport protein SCO0374 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21220343 Common - precorrin-4 C11-methyltransferase SCO1855 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 21225400 Common - hypothetical protein SCO7118 3 None None None 21223664 Common - secreted penicillin-binding protein SCO5301 205 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21219769 Common - transcriptional regulatory protein SCO1261 98 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21222959 Common - hypothetical protein SCO4576 7 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 21224709 Common - hypothetical protein SCO6401 13 None None None 21220929 Nonpathogen - hypothetical protein SCO2466 4 None None None 21220438 Common uvrC excinuclease ABC subunit C SCO1953 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 21222544 Common - ECF subfamily sigma factor SCO4146 51 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220099 Common - hypothetical protein SCO1602 10 None None None 21225339 Common - gntR-family transcriptional regulator SCO7056 17 COG2188 PhnF, Transcriptional regulators Transcription 21224672 Common - integral membrane protein SCO6359 5 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 21223274 Common - hypothetical protein SCO4900 6 COG0400 COG0400, Predicted esterase General function prediction only 21220489 Nonpathogen - hypothetical protein SCO2007 1 None None None 21219557 Common - hypothetical protein SCO1041 105 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 21222439 Common - hypothetical protein SCO4036 4 None None None 32141221 Common - ftsK/spoIIIE family protein SCO3934 43 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21223613 Common - Na+/H+ antiporter SCO5246 101 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 21221692 Common - korSA, regulatory protein SCO3259 128 COG2188 PhnF, Transcriptional regulators Transcription 21224712 Nonpathogen - hypothetical protein SCO6404 1 None None None 21222931 Nonpathogen - secreted protein SCO4547 4 None None None 21219505 Common - acetyltransferase SCO0988 4 None None None 21223214 Nonpathogen - hypothetical protein SCO4838 1 None None None 21218949 Common - transcriptional regulator SCO0407 50 COG0789 SoxR, Predicted transcriptional regulators Transcription 21221538 Common - cytochrome P450 hydroxylase SCO3099 88 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21224821 Common - lyase SCO6519 42 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21219148 Common - secreted protein SCO0615 4 None None None 21222603 Common - hypothetical protein SCO4207 15 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 21219839 Nonpathogen - integral membrane protein SCO1333 1 None None None 21224285 Common - integral membrane protein SCO5947 89 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219248 Common - hydrolase SCO0722 75 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 21221507 Common - regulator of Sig15 SCO3066 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220074 Common - arginine repressor SCO1576 79 COG1438 ArgR, Arginine repressor Transcription 21221636 Common - tetR-family transcriptional regulator SCO3201 48 COG1309 AcrR, Transcriptional regulator Transcription 21222622 Nonpathogen - hypothetical protein SCO4226 4 None None None 21219934 Nonpathogen - membrane protein SCO1431 1 None None None 21223397 Common - oxidoreductase SCO5024 38 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21219457 Common - amino acid transporter protein SCO0938 138 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21223023 Common - transmembrane efflux protein SCO4641 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219541 Nonpathogen - integral membrane protein SCO1025 3 None None None 21222683 Common - trehalose-phosphate synthase SCO4290 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 21218834 Common - probable secreted alpha-galactosidase SCO0284 22 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 21219832 Common uppP undecaprenyl pyrophosphate phosphatase SCO1326 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 21221743 Common - hypothetical protein SCO3312 14 None None None 21222866 Common - secreted hydrolase SCO4479 52 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225972 Nonpathogen - hypothetical protein SCO7713 1 None None None 21223309 Common - integral membrane protein SCO4935 7 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 21220831 Common - ATP/GTP-binding protein SCO2363 22 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 21219797 Common - gntR-family regulatory protein SCO1289 168 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 21225802 Common - aminotransferase SCO7537 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 21222771 Common - acetyl/propionyl CoA carboxylase, alpha subunit SCO4381 224 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 21222969 Nonpathogen - ABC transporter integral membrane protein SCO4586 5 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 21225205 Nonpathogen - hypothetical protein SCO6917 1 None None None 21219021 Nonpathogen - secreted protein SCO0483 1 None None None 21221134 Common - hypothetical protein SCO2678 4 None None None 21221493 Common - acyl-CoA dehydrogenase SCO3051 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21222654 Common - AAA family ATPase SCO4259 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 21220255 Common - iron-sulphur protein (secreted protein) SCO1763 51 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 21220678 Common - hypothetical protein SCO2205 2 None None None 21222413 Common - secreted protein SCO4010 4 None None None 21222681 Common - phosphatase SCO4288 67 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 21225141 Nonpathogen - hypothetical protein SCO6850 1 None None None 21219898 Common - glycosyl hydrolase SCO1394 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 161353681 Common pheS phenylalanyl-tRNA synthetase subunit alpha SCO1595 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 21223483 Common - BldKA, ABC transport system integral membrane protein SCO5112 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21224838 Common - hypothetical protein SCO6536 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21225502 Common - secreted chitinase SCO7225 22 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 21219838 Nonpathogen - hypothetical protein SCO1332 2 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21224812 Nonpathogen - hydrophobic protein SCO6509 1 None None None 21224601 Common - 3-oxoacyl-[acyl-carrier protein] reductase SCO6282 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21220473 Common - hypothetical protein SCO1991 90 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 21224890 Common - secreted esterase SCO6590 10 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 21221281 Common - probable amino acid ABC transporter protein, ATP-binding component SCO2831 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 21221936 Common - integral membrane protein SCO3515 7 None None None 21222476 Nonpathogen - integral membrane protein SCO4074 1 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21224019 Common - polyamine ABC-transporter integral memb rane protein SCO5669 173 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 21221877 Common - methyltransferase SCO3452 70 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221437 Common - hypothetical protein SCO2993 4 None None None 21222212 Nonpathogen - hypothetical protein SCO3802 2 None None None 21223198 Nonpathogen - hypothetical protein SCO4821 1 None None None 21219169 Common - lipoprotein SCO0638 67 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 21221514 Common - urocanate hydratase SCO3073 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 21225138 Nonpathogen - hypothetical protein SCO6846 1 None None None 21221531 Common - cyclopropane-fatty-acyl-phospholipid synthase SCO3091 160 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 21220906 Common - gntR-family transcriptional regulator SCO2442 140 COG2186 FadR, Transcriptional regulators Transcription 21224603 Common - decarboxylase SCO6284 200 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 21219357 Common - hypothetical protein SCO0836 221 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 21221106 Common - 4-alpha-glucanotransferase SCO2649 117 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 21221187 Common - LysR-family transcriptional regulator SCO2734 122 COG0583 LysR, Transcriptional regulator Transcription 21221412 Common - carboxy-terminal processing protease precursor SCO2967 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 21223942 Common - cell division protein FtsH homolog SCO5587 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 21221728 Common - oxidoreductase SCO3296 80 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21223655 Common - hypothetical protein SCO5290 8 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21225636 Common - oxidoreductase SCO7362 201 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 21225876 Common - regulatory protein SCO7614 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 31340549 Common - hypothetical protein SCO1816 166 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 21220714 Common - probable serine/threonine protein kinase SCO2244 158 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21218882 Common - transcriptional regulator SCO0337 22 COG1309 AcrR, Transcriptional regulator Transcription 21220351 Nonpathogen - hypothetical protein SCO1863 1 None None None 21225118 Common - hypothetical protein SCO6826 15 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 21224618 Common - secreted hydrolase SCO6300 181 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21223675 Common - hypothetical protein SCO5312 11 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 21224997 Common - 3-oxoadipate CoA-transferase subunit A SCO6703 98 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 21221799 Common - large ATP-binding protein SCO3370 19 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 21220666 Common - regulator SCO2192 6 None None None 21222211 Common - putative aminopeptidase 2 SCO3801 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 32141249 Common - secreted hydrolase SCO4860 61 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 21222560 Common - integral membrane protein SCO4162 3 COG0730 COG0730, Predicted permeases General function prediction only 21224725 Common - hypothetical protein SCO6418 3 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 21225541 Common - oxidoreductase SCO7264 153 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21222119 Common - ABC transporter ATP-binding subunit SCO3706 248 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 21219471 Common - lacI-family transcriptional regulator SCO0953 124 COG1609 PurR, Transcriptional regulators Transcription 21225304 Common - secreted alpha-amylase SCO7019 138 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 32141286 Common - peptide ABC transporter integral membrane protein SCO6113 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21218979 Common - hypothetical protein SCO0437 19 None None None 21225188 Common - carboxylase SCO6898 195 COG0439 AccC, Biotin carboxylase Lipid metabolism 21219945 Common - riboflavin synthase subunit alpha SCO1443 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 21224654 Common - exonuclease SCO6341 191 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 21222272 Nonpathogen - secreted protein SCO3863 1 None None None 21224943 Common - transport system permease protein SCO6646 42 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221855 Common rpmG 50S ribosomal protein L33 SCO3428 122 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 21222430 Common - anti sigma factor antagonist SCO4027 3 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21224632 Nonpathogen - hypothetical protein SCO6316 1 None None None 21224872 Common - DNA-binding protein SCO6571 59 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21219655 Common - hypothetical protein SCO1141 38 COG0432 COG0432, Uncharacterized conserved protein Function unknown 21221270 Nonpathogen - hypothetical protein SCO2820 1 None None None 21224118 Common - hypothetical protein SCO5772 7 None None None 21221122 Common - serine/threonine protein kinase SCO2666 124 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21223799 Common - glycogen branching enzyme SCO5440 149 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 21221761 Common - acetoin utilization protein SCO3330 159 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 21222569 Nonpathogen - hypothetical protein SCO4172 1 None None None 21221113 Common - hypothetical protein SCO2656 102 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 21222818 Nonpathogen - secreted protein SCO4430 2 None None None 21223139 Common - secreted protein SCO4760 24 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21223154 Common - serine/threonine protein kinase SCO4775 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21222416 Common - secreted penicillin-binding protein SCO4013 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 21225091 Common - hypothetical protein SCO6798 52 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 21221357 Common - cysteine synthase SCO2910 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 21225155 Nonpathogen - hypothetical protein SCO6864 2 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 21224978 Nonpathogen - hypothetical protein SCO6682 1 None None None 21219084 Common - acyl carrier protein SCO0549 103 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21221350 Nonpathogen - secreted protein SCO2903 1 None None None 21225231 Common - hypothetical protein SCO6944 67 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 21221475 Common - secreted protein SCO3032 9 None None None 21223908 Common - isopropylmalate isomerase large subunit SCO5553 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 21219226 Common - hypothetical protein SCO0699 5 None None None 21223901 Common - hypothetical protein SCO5546 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 21221381 Common - secreted protein SCO2934 63 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 21219700 Nonpathogen - hypothetical protein SCO1189 1 None None None 32141150 Common - gluconate permease SCO1680 78 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 21221376 Common - transposase SCO2929 67 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220225 Common - hypothetical protein SCO1731 187 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21219143 Common - gntR-family transcriptional regulator SCO0610 107 COG2188 PhnF, Transcriptional regulators Transcription 21225555 Common - RNA polymerase sigma factor SCO7278 214 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21222938 Nonpathogen - integral membrane transferase SCO4555 2 None None None 21222740 Common - hypothetical protein SCO4349 10 None None None 21224860 Common - formate dehydrogenase accessory protein SCO6558 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 21222575 Nonpathogen - small membrane protein SCO4178 1 None None None 21219543 Common - hypothetical protein SCO1027 4 None None None 21224888 Common - hypothetical protein SCO6588 33 COG4325 COG4325, Predicted membrane protein Function unknown 21224153 Common - hypothetical protein SCO5808 11 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21225738 Common - phenylacetic acid degradation protein PaaI SCO7470 59 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 21222360 Common - hypothetical protein SCO3955 6 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 21224687 Common - secreted protein SCO6375 54 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 21218806 Common - tetR-family transcriptional regulator SCO0253 14 COG1309 AcrR, Transcriptional regulator Transcription 21219598 Common - flavin-dependent reductase SCO1083 114 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 21223051 Common - serine protease precursor SCO4670 15 None None None 21222220 Common - gntR-family transcriptional regulator SCO3810 38 COG1802 GntR, Transcriptional regulators Transcription 21219783 Common - halogenase SCO1275 37 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21221427 Common - glycosyl transferase SCO2983 205 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 21225765 Common - transcriptional regulator SCO7498 126 COG1802 GntR, Transcriptional regulators Transcription 21218952 Common - hypothetical protein SCO0410 220 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 21224756 Common - hypothetical protein SCO6450 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 21222491 Common - valine dehydrogenase SCO4089 142 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 21222661 Common - hypothetical protein SCO4268 45 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 21218622 Common - hypothetical protein SCO0043 39 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21220567 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase SCO2087 212 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 21221706 Nonpathogen - hypothetical protein SCO3273 1 None None None 21226063 Common - hypothetical protein SCO7813 33 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21219861 Common - secreted serine protease SCO1355 118 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21223599 Common - gntR-family transcriptional regulator SCO5231 126 COG2188 PhnF, Transcriptional regulators Transcription 21225591 Nonpathogen - hypothetical protein SCO7315 1 None None None 21221656 Common - prephenate dehydrogenase SCO3221 145 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 21221449 Common - acetyltransferase SCO3006 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 32141103 Common - sigma factor SCO0255 149 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 21223864 Common - oxidoreductase SCO5508 120 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 21220908 Common - acyl-CoA synthetase SCO2444 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222899 Nonpathogen - integral membrane protein SCO4514 1 None None None 21223497 Nonpathogen - integral membrane protein SCO5127 1 None None None 21219585 Common - two component system response regulator SCO1070 208 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21224185 Common - phosphocarrier protein hpr SCO5841 21 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 21225251 Common - hypothetical protein SCO6964 11 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 21225872 Common - transcriptional regulator SCO7610 76 COG2378 COG2378, Predicted transcriptional regulator Transcription 21222403 Nonpathogen - hypothetical protein 2SC10A704c SCO4000 1 None None None 21224428 Common - adenylylsulfate kinase SCO6099 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 21225644 Common - NAD-dependent dehydratase SCO7370 218 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21218784 Nonpathogen - small hydrophobic hypothetical protein SCO0231 1 None None None 21222808 Common - hypothetical protein SCO4419 4 None None None 21223283 Common - ATP-binding protein SCO4909 3 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 21219098 Common - hypothetical protein SCO0564 14 None None None 21222064 Common - fructose-bisphosphate aldolase SCO3649 172 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 21225056 Common - polyprenyl synthatase SCO6763 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 21224768 Common - methylated-DNA-protein-cysteine methyltransferase SCO6462 206 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 21220973 Nonpathogen - hypothetical protein SCO2512 1 None None None 21225444 Nonpathogen - hypothetical protein SCO7164 1 None None None 21223025 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase SCO4643 201 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 21221299 Common - hypothetical protein SCO2849 11 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21219425 Common - membrane protein SCO0905 8 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225871 Common - esterase SCO7609 6 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225379 Common - MarR-family regulatory protein SCO7097 59 COG1846 MarR, Transcriptional regulators Transcription 21225890 Common - probable starvation sensing protein SCO7629 99 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21220193 Common - hypothetical protein SCO1698 70 COG2030 MaoC, Acyl dehydratase Lipid metabolism 21223481 Common - lipoprotein SCO5110 34 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21222858 Common - secreted protein SCO4471 11 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21220688 Common - two-component system response regulator SCO2216 171 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21218974 Common - probable secreted peptidase SCO0432 143 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21220962 Common - DNA-binding protein SCO2501 41 None None None 21220124 Common - hypothetical protein SCO1628 8 None None None 21220261 Common - hypothetical protein SCO1769 143 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 21223186 Common sucC succinyl-CoA synthetase subunit beta SCO4808 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 21224291 Common - hypothetical protein SCO5953 51 COG2319 COG2319, FOG: WD40 repeat General function prediction only 21224599 Common - regulatory protein SCO6280 22 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21225289 Nonpathogen - hypothetical protein SCO7003 2 None None None 21219634 Common - hydrolase SCO1120 186 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 21221486 Common - hypothetical protein SCO3043 61 COG1316 LytR, Transcriptional regulator Transcription 21220988 Nonpathogen - hypothetical protein SCO2527 1 None None None 21220535 Common hisD histidinol dehydrogenase SCO2054 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 21220778 Common - transmembrane transport protein SCO2309 171 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224810 Common - gas vesicle synthesis protein SCO6507 5 None None None 21222034 Common recR recombination protein RecR SCO3618 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 21225561 Common - ribonuclease H SCO7284 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 21223554 Common - peptidase SCO5185 170 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 21220094 Common - rRNA methylase SCO1597 210 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 21223395 Nonpathogen - lipoprotein SCO5022 1 None None None 21223079 Common - Rhs protein SCO4699 69 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 21224865 Common - integral membrane transporter SCO6563 86 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 21222250 Common - hypothetical protein SCO3841 29 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 21220515 Common - prolipoprotein diacylglyceryl transferase SCO2034 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 21220707 Common - hypothetical protein SCO2236 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 21221834 Common - hypothetical protein SCO3407 27 COG5282 COG5282, Uncharacterized conserved protein Function unknown 21220105 Nonpathogen - hypothetical protein SCO1608 1 None None None 21218687 Common - multi-domain beta keto-acyl synthase SCO0127 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21222824 Common - lyase SCO4436 34 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21225078 Common - probable fatty acid co-A racemase SCO6785 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 21221263 Common - hypothetical protein SCO2813 36 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 21221325 Common - acetyltransferase SCO2876 156 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21225041 Common - hypothetical protein SCO6747 73 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21222734 Common - hypothetical protein SCO4342 12 None None None 21223902 Common gltX glutamyl-tRNA synthetase SCO5547 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 21220744 Common - lipoprotein SCO2275 28 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 21219759 Common - acetyltransferase SCO1250 32 COG0456 RimI, Acetyltransferases General function prediction only 32141255 Common - hypothetical protein SCO5138 14 None None None 21223381 Nonpathogen - septum site-determining protein SCO5008 1 None None None 21223736 Common - chitinase C (secreted protein) SCO5376 49 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 21222567 Nonpathogen - hypothetical protein SCO4170 1 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 21219650 Common - two component system response regulator SCO1136 62 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 21219752 Common - 8-amino-7-oxononanoate synthase SCO1243 182 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 21220382 Common - 5-dehydro-4-deoxyglucarate dehydratase SCO1895 217 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 21219314 Common - hypothetical protein SCO0792 74 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21221997 Common - regulatory protein SCO3579 19 None None None 21225080 Common - probable acyl-CoA dehydrogenase SCO6787 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21223232 Common sdhA succinate dehydrogenase flavoprotein subunit SCO4856 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 21220416 Common - integral membrane transport protein SCO1930 19 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 21225566 Nonpathogen - regulator SCO7289 6 None None None 21219695 Common - hypothetical protein SCO1184 25 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 21224096 Common - ftsK homolog SCO5750 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21220455 Common - hypothetical protein SCO1971 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21220314 Nonpathogen - membrane protein SCO1825 1 None None None 21225583 Common - chromosome replication initiation inhibitor protein SCO7307 131 COG0583 LysR, Transcriptional regulator Transcription 21221553 Nonpathogen - hypothetical protein SCO3114 1 None None None 21221622 Common - hypothetical protein SCO3187 74 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 21222085 Nonpathogen - cell surface biosynthesis associated protein SCO3672 4 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 21224046 Common - hypothetical protein SCO5697 18 COG3393 COG3393, Predicted acetyltransferase General function prediction only 21225319 Common - argininosuccinate synthase SCO7036 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 21221021 Common - GTP-binding protein LepA SCO2562 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 21226047 Nonpathogen - transposase SCO7795 3 None None None 21221610 Common - merR-family transcriptional regulator SCO3173 22 COG0789 SoxR, Predicted transcriptional regulators Transcription 21225499 Common - TetR-family transcriptional regulator SCO7222 9 COG1309 AcrR, Transcriptional regulator Transcription 21219518 Nonpathogen - hypothetical protein 2SCG214 SCO1001 1 None None None 21219605 Common - phosphodiesterase SCO1090 183 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 21226055 Nonpathogen - hypothetical protein SCO7805 1 None None None 21222451 Common - hypothetical protein SCO4048 44 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 21219266 Common - oxidoreductase SCO0741 210 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 21223046 Nonpathogen - hypothetical protein SCO4665 1 None None None 21223917 Common - hypothetical protein SCO5561 37 COG1522 Lrp, Transcriptional regulators Transcription 21221987 Common - endonuclease SCO3569 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 21223476 Common - hypothetical protein SCO5105 2 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 21220305 Common - 3-oxacyl-(ACP) reductase SCO1815 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21223938 Common - regulator SCO5582 6 None None None 32141198 Common lysK lysyl-tRNA synthetase SCO3303 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 21219657 Common - hypothetical protein SCO1143 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 21220603 Common - hypothetical protein SCO2125 13 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 21223895 Common - membrane protein SC1C221c SCO5540 29 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21219668 Common - hypothetical protein SCO1155 10 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21221776 Common - transcriptional regulator SCO3346 99 COG1309 AcrR, Transcriptional regulator Transcription 21224696 Common - integral membrane lysyl-tRNA synthetase SCO6384 48 COG2898 COG2898, Uncharacterized conserved protein Function unknown 21220548 Common - hypothetical protein SCO2067 16 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 21218938 Common - epimerase/dehydratase SCO0395 207 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21219879 Nonpathogen - secreted protein SCO1374 2 None None None 21224899 Common - transcriptional regulator SCO6599 18 COG1309 AcrR, Transcriptional regulator Transcription 21225395 Nonpathogen - integral membrane protein SCO7113 1 None None None 21218835 Common - sodium/proton antiporter SCO0285 143 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 21225993 Nonpathogen - hypothetical protein SCO7734 1 None None None 21220111 Common - transcriptional regulator SCO1614 11 COG2186 FadR, Transcriptional regulators Transcription 21225683 Common - short chain dehydrogenase SCO7413 137 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21222351 Common - cytochrome oxidase subunit II SCO3946 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 21225469 Nonpathogen - hypothetical protein SCO7190 1 None None None 21225834 Common - isomerase SCO7570 124 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21218585 Nonpathogen - DNA-binding protein SCO0003 2 None None None 21218612 Common - secreted neuraminidase SCO0033 20 None None None 21218922 Common - catalase SCO0379 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 21225548 Common - ion channel subunit SCO7271 185 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21221063 Common - hypothetical protein SCO2605 4 None None None 21221212 Nonpathogen - membrane protein SCO2760 1 None None None 21225390 Common - hypothetical protein SCO7108 44 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223725 Common - transferase SCO5365 223 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 21221453 Common - hypothetical protein SCO3010 8 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 21222236 Common - ion channel membrane protein SCO3826 113 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 21222923 Nonpathogen - hypothetical protein SCO4539 2 None None None 21218826 Common - oxidoreductase SCO0276 177 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21219494 Common - hypothetical protein SCO0977 15 COG2388 COG2388, Predicted acetyltransferase General function prediction only 21220507 Common - glutamate synthase large subunit SCO2026 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 21222751 Common - ABC transport system integral membrane protein SCO4360 93 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21220638 Common - hypothetical protein SCO2161 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 21220712 Nonpathogen - membrane protein SCO2242 2 COG5500 COG5500, Predicted integral membrane protein Function unknown 21225385 Nonpathogen - hypothetical protein SCO7103 1 None None None 21221301 Common - membrane protein SCO2851 194 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 21220017 Common - secreted protein SCO1517 28 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 21221171 Nonpathogen - small membrane protein SCO2717 1 None None None 21223568 Common - hypothetical protein SCO5199 27 COG5282 COG5282, Uncharacterized conserved protein Function unknown 21224089 Common thyX FAD-dependent thymidylate synthase SCO5743 36 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 21220736 Common - probable heme oxygenase SCO2267 24 COG5398 COG5398, Heme oxygenase Inorganic ion transport and metabolism 21219464 Common - formamidopyrimidine-DNA glycosylase SCO0945 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 21224495 Common - oxidoreductase subunit SCO6170 91 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 21226027 Common - secreted protein SCO7774 14 None None None 21222470 Common - phosphoribosylamine-glycine ligase SCO4068 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 21219974 Common - conserved hypothetical Sun-family protein SCL629c SCO1472 183 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 21220205 Common - integral membrane transport protein SCO1710 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 21219259 Common - transcriptional repressor SCO0734 77 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21225852 Common - oxidoreductase SCO7588 34 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223611 Common - anti-sigma factor SCO5244 11 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220280 Common - hypothetical protein SCO1788 117 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 21225170 Nonpathogen - hypothetical protein SCO6879 1 None None None 21224551 Common - sugar transport system permease protein SCO6229 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21225804 Common - TetR-family transcriptional regulator SCO7539 36 COG1309 AcrR, Transcriptional regulator Transcription 21223096 Common rpsH 30S ribosomal protein S8 SCO4716 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 21224680 Nonpathogen - lipoprotein SCO6368 4 None None None 21223914 Common - acyltransferase SCO5558 101 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21224512 Common - transferase SCO6188 15 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 21219016 Common - ABC transport protein, ATP-binding subunit SCO0476 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 21226036 Common - transcriptional regulator SCO7785 15 None None None 21219821 Common - sugar acetyltransferase SCO1314 19 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 21225275 Common - hypothetical protein SCO6989 12 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 21223014 Common - ATP/GTP binding protein SCO4632 43 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 21222460 Common - transport integral membrane protein SCO4057 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 21224535 Common - permease SCO6212 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 21226072 Nonpathogen - membrane protein SCO7823 3 None None None 21222153 Common - response regulator SCO3741 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21219846 Common - hypothetical protein SCO1340 13 None None None 32141242 Nonpathogen - hypothetical protein SCO4630 1 None None None 21220969 Common - metal uptake regulation protein SCO2508 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 21220823 Common - lipoprotein SCO2355 8 None None None 21219279 Common - ABC transporter SCO0755 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 21225051 Common - ABC transporter ATP-binding protein SCO6758 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 21218603 Common - IS element ATP-binding protein SCO0022 79 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 21219803 Common - hypothetical protein SCO1296 38 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 21219820 Common - integral membrane protein SCO1313 11 COG2510 COG2510, Predicted membrane protein Function unknown 21218770 Common - nitrate reductase alpha chain NarG2 SCO0216 107 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 21221098 Common - resistance protein SCO2641 28 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21223625 Common - ATP-binding protein SCO5258 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 21220256 Common - hypothetical protein SCO1764 23 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 21221219 Common - ATP/GTP-binding protein SCO2767 26 None None None 21218843 Common - acetyltransferase SCO0294 70 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 21223387 Nonpathogen - secreted protein SCO5014 3 None None None 21225915 Common - oxidoreductase SCO7654 190 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21219537 Common - hypothetical protein SCO1020 26 COG4110 COG4110, Uncharacterized protein involved in stress response General function prediction only 21225856 Common - hypothetical protein SCO7593 6 None None None 21221335 Common - hydrolase SCO2886 172 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21224446 Common - AraC family transcriptional regulator SCO6119 17 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21220241 Common - hypothetical protein SCO1747 22 COG3358 COG3358, Uncharacterized conserved protein Function unknown 21225962 Common - integral membrane transport protein SCO7703 69 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 21223072 Nonpathogen - hypothetical protein SCO4692 2 None None None 21224055 Common - small conserved hypothetical protein SCO5707 34 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 21221244 Common - oligoribonuclease SCO2793 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 21225358 Common - two component response regulator protein SCO7075 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21222552 Common - hypothetical protein SCO4154 82 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21221078 Nonpathogen - hypothetical protein SCO2621 1 None None None 21225757 Common - binding protein dependent transport lipoprotein SCO7489 9 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21225162 Common - lipoprotein SCO6871 3 None None None 21223603 Common - sugar hydrolase SCO5235 182 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21221675 Common - puitative transferase SCO3242 3 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 21223413 Common - hypothetical protein SCO5040 91 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21219827 Common - elongation factor Tu SCO1321 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 21218927 Nonpathogen - hypothetical protein SCO0384 1 None None None 21222620 Nonpathogen - hypothetical protein SCO4224 1 None None None 21223777 Common - zinc-binding oxidoreductase SCO5417 166 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21222538 Common - phosphate ABC transport system permease protein SCO4140 229 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 21221912 Common - transposase SCO3490 44 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 21225113 Common - oxidoreductase SCO6820 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 21219039 Common - secreted protein SCO0501 56 COG2936 COG2936, Predicted acyl esterases General function prediction only 21220299 Common - hypothetical protein SCO1809 70 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 32141327 Common - serine/threonine protein kinase SCO7291 89 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21224496 Common - oxidoreductase SCO6171 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 21218753 Common - hypothetical protein SCO0197 9 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21223527 Common - hypothetical protein SCO5158 5 None None None 21219276 Common - protease precursor SCO0752 22 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21219220 Nonpathogen - membrane protein SCO0692 1 None None None 21222281 Common - DNA gyrase subunit A SCO3873 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 21220002 Common alaS alanyl-tRNA synthetase SCO1501 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21220763 Common - araC-family regulatory protein SCO2294 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21218988 Common - hypothetical protein SCO0446 2 None None None 21224982 Nonpathogen - DNA-binding protein SCO6687 2 None None None 21219724 Common - 6-phosphofructokinase SCO1214 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 21225676 Common - secreted protein SCO7406 8 COG5520 COG5520, O-Glycosyl hydrolase Cell envelope biogenesis, outer membrane 21223222 Common - integral membrane protein SCO4846 22 COG1295 Rbn, Predicted membrane protein Function unknown 21222162 Common - two-component sensor histidine kinase SCO3750 12 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223789 Common - extracellular solute-binding lipoprotein SCO5430 96 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21221907 Common - integral membrane transport protein SCO3483 160 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21221229 Common - hydroxymethylglutaryl-CoA lyase SCO2778 190 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 21223420 Common glpX fructose 1,6-bisphosphatase II SCO5047 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 21219511 Common - integral membrane protein SCO0994 89 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21222709 Common - ATP/GTP binding protein SCO4316 36 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 21225851 Common - integral membrane protein SCO7587 6 None None None 21224128 Common - hypothetical protein SCO5783 22 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 21218811 Common - hypothetical protein SCO0260 23 COG1359 COG1359, Uncharacterized conserved protein Function unknown 21225290 Common - probable carbohydrate kinase SCO7004 177 COG0554 GlpK, Glycerol kinase Energy production and conversion 21224544 Common - aminotransferase AlaT SCO6222 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 21223247 Common - hypothetical protein SCO4872 4 None None None 21224419 Common - antibiotic resistance macrolide glycosyltransferase SCO6090 36 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 21219231 Common - hypothetical protein SCO0705 12 None None None 21219574 Common - beta-glucosidase SCO1059 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 21224836 Common - nitrate reductase beta chain NarH SCO6534 149 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 21218610 Nonpathogen - hypothetical protein SCO0031 1 None None None 21221865 Common - hypothetical protein SCO3439 39 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 21224250 Common - oligopeptide binding protein SCO5911 191 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21220728 Common - multi-domain regulatory protein SCO2259 29 COG3903 COG3903, Predicted ATPase General function prediction only 21221460 Common - secreted protein SCO3017 10 None None None 21222726 Common - integral membrane protein SCO4334 135 COG2252 COG2252, Permeases General function prediction only 21223329 Common - methionine sulfoxide reductase A SCO4956 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 21218707 Nonpathogen - hypothetical protein SCO0149 1 None None None 21225323 Common - glyceraldehyde-3-phosphate dehydrogenase SCO7040 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 21218997 Common - LacI family transcriptional regulator SCO0456 126 COG1609 PurR, Transcriptional regulators Transcription 21220185 Common - acyl-CoA dehydrogenase SCO1690 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21222181 Common - cytochrome P450 oxidoreductase SCO3770 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 32141163 Common - secreted protein SCO2239 25 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 21222328 Common - hypothetical protein SCO3922 74 COG1950 COG1950, Predicted membrane protein Function unknown 21221755 Nonpathogen - hypothetical protein SCO3324 4 None None None 21225671 Common - ABC transporter ATP-binding protein SCO7400 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 21219486 Common - hypothetical protein SCO0968 2 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21222509 Common - probable peptidase SCO4108 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21222713 Common - hypothetical protein SCO4321 15 COG2378 COG2378, Predicted transcriptional regulator Transcription 21218840 Common - probable solute-binding protein SCO0290 96 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219378 Common - TetR-family regulator SCO0857 28 COG1309 AcrR, Transcriptional regulator Transcription 21221900 Common - short-chain dehydrogenase SCO3476 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21220242 Common - hypothetical protein SCO1749 46 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 21225488 Common - secreted glycosyl hydrolase SCO7211 36 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 21221896 Nonpathogen - transposase remnant SCO3472 1 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220024 Common - hypothetical protein SCO1524 7 COG1704 LemA, Uncharacterized conserved protein Function unknown 21225603 Nonpathogen - regulatory protein SCO7328 1 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21224571 Common - transport protein SCO6250 18 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 21220911 Common - hypothetical protein SCO2447 7 None None None 21219335 Common - rhamnose kinase SCO0814 83 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 21223549 Common - peptidase SCO5180 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221043 Nonpathogen - membrane protein SCO2584 1 None None None 21223067 Nonpathogen - hypothetical protein SCO4687 1 None None None 21223893 Common - hypothetical protein SCO5538 9 None None None 21220953 Common - dehydrogenase (secreted protein) SCO2490 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221039 Nonpathogen - membrane protein SCO2580 1 None None None 21221660 Common - two component sensor kinase SCO3225 64 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21222892 Common - serine/threonine protein kinase SCO4507 93 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21222706 Common - regulatory protein SCO4313 20 COG1309 AcrR, Transcriptional regulator Transcription 21220156 Common - glycerol kinase SCO1660 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 21222910 Common - hypothetical protein SCO4525 6 COG5283 COG5283, Phage-related tail protein Function unknown 21224964 Common - two-component sensor SCO6668 55 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21219526 Nonpathogen - transposase SCO1009 3 None None None 21223229 Common - hypothetical protein SCO4853 3 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21224958 Common - transaldolase SCO6662 121 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 21223043 Common tuf elongation factor Tu SCO4662 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 21220148 Common - hypothetical protein SCO1652 75 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 21220484 Nonpathogen - hypothetical protein SCO2002 1 None None None 21220751 Common - hypothetical protein SCO2282 15 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 21220920 Common - integral membrane protein SCO2456 10 None None None 21225662 Common - short chain dehydrogenase SCO7389 160 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21221056 Common - dehydrogenase SCO2598 92 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 21221779 Common - hypothetical protein SCO3349 9 None None None 21224300 Common - transcriptional regulator SCO5962 135 COG0789 SoxR, Predicted transcriptional regulators Transcription 32141144 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase SCO1477 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 21220208 Nonpathogen - secreted protein SCO1714 1 None None None 21221733 Nonpathogen - secreted protein SCO3301 1 None None None 21222975 Common - integral membrane protein SCO4592 103 COG2962 RarD, Predicted permeases General function prediction only 21220541 Nonpathogen - integral membrane transport protein SCO2060 3 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21224312 Common - arginine deiminase SCO5975 56 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 21225659 Common - secreted serine protease SCO7386 9 None None None 21221087 Common - biotin synthase SCO2630 55 COG1268 BioY, Uncharacterized conserved protein General function prediction only 21221345 Common - molecular chaperone SCO2898 109 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 21225037 Common - transcriptional accessory protein SCO6743 140 COG2183 Tex, Transcriptional accessory protein Transcription 21221104 Common - MarR-family regulatory protein SCO2647 60 COG1846 MarR, Transcriptional regulators Transcription 21223160 Common - cholesterol oxidase SCO4781 39 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 21225098 Common - integral membrane efflux protein SCO6805 35 None None None 21225950 Common - ABC transporter ATP-binding protein SCO7690 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21221308 Nonpathogen - hypothetical protein SCO2858 1 COG4709 COG4709, Predicted membrane protein Function unknown 21219690 Common - hypothetical protein SCO1179 18 COG3361 COG3361, Uncharacterized conserved protein Function unknown 21219744 Common ureB urease subunit beta SCO1235 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 21222627 Common - transcriptional factor regulator SCO4232 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 21222963 Common - fumarylacetoacetase SCO4580 47 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 21223101 Common rplO 50S ribosomal protein L15 SCO4721 207 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 21224826 Common - integral membrane protein SCO6524 32 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21222701 Common - transcriptional regulator SCO4308 105 COG1737 RpiR, Transcriptional regulators Transcription 21219046 Common glpK glycerol kinase SCO0509 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 21223408 Common - ABC transporter ATP-binding protein SCO5035 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21224527 Nonpathogen - hypothetical protein SCO6203 1 None None None 21225355 Common - hypothetical protein SCO7072 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 21225476 Common - amino acid transport integral membrane protein SCO7197 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 21224123 Common - glutamate uptake system ATP-binding protein SCO5777 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 21222601 Common - hypothetical protein SCO4205 10 None None None 21224239 Common - probable membrane protein SCO5898 21 COG3752 COG3752, Predicted membrane protein Function unknown 21223967 Common - ATP binding protein SCO5612 52 COG3378 COG3378, Predicted ATPase General function prediction only 21222045 Nonpathogen - hypothetical protein SCO3630 2 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 21221324 Common - MerR-family transcriptional regulator SCO2875 38 COG0789 SoxR, Predicted transcriptional regulators Transcription 21223761 Common - probable integral membrane protein SCO5401 3 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221310 Common - rifampin ADP-ribosyl transferase SCO2860 11 None None None 21223878 Common - branched-chain amino acid aminotransferase SCO5523 202 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 21225596 Common - hypothetical protein SCO7320 77 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21220043 Nonpathogen - hypothetical protein SCO1543 1 None None None 21221968 Common - anti-sigma factor antagonist SCO3549 61 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21224481 Common - pyruvate dehydrogenase SCO6155 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 21224078 Common - secreted serine protease SCO5731 134 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21225417 Common - hypothetical protein SCO7135 41 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 21224724 Common - integral membrane transporter SCO6417 63 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 21219288 Common - hydrolase SCO0764 5 None None None 21219105 Common - hypothetical protein SCO0571 197 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 21223401 Common - ATP-binding protein SCO5028 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 21223941 Common - signal recognition particle protein SCO5586 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 21222358 Common - phosphotransferase SCO3953 44 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 21222132 Nonpathogen - small membrane protein SCO3719 1 None None None 21223267 Common - transport integral membrane protein SCO4893 59 COG0679 COG0679, Predicted permeases General function prediction only 21224407 Common - alpha amylase SCO6078 127 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 21218794 Common - transcriptional regulator SCO0241 15 COG1309 AcrR, Transcriptional regulator Transcription 21219623 Common - oxidoreductase SCO1109 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 21221395 Common - DNA-binding protein Hu (hs1) SCO2950 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 21222204 Common - hypothetical protein SCO3793 29 None None None 21223927 Common rpmF 50S ribosomal protein L32 SCO5571 69 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 21224061 Common - ABC transporter ATP-binding protein SCO5713 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21223438 Common - beta-lactamase SCO5066 81 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21223563 Common - hypothetical protein SCO5194 139 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 21225721 Common - O-methyltransferase SCO7452 47 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21220814 Common - hydrolase SCO2346 104 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 21220996 Common - DNA-binding protein SCO2537 42 None None None 21225772 Common - integral membrane binding-protein-dependent transport protein SCO7505 161 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21220410 Common - hypothetical protein SCO1924 175 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 32141196 Common - CDA peptide synthetase III SCO3232 214 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21219941 Common hisE phosphoribosyl-ATP pyrophosphatase SCO1439 19 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 21221470 Common - hypothetical protein SCO3027 70 COG2835 COG2835, Uncharacterized conserved protein Function unknown 21220941 Common - reductase SCO2478 85 COG0431 COG0431, Predicted flavoprotein General function prediction only 21223705 Nonpathogen - SpdD2 protein SCO5344 1 None None None 21225262 Common - hypothetical protein SCO6976 51 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 21223149 Common - inosine 5' monophosphate dehydrogenase SCO4770 238 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 21224366 Nonpathogen - hypothetical protein SCO6034 1 None None None 21223859 Common - acetyltransferase SCO5503 42 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21219649 Common - tetR-family transcriptional regulator SCO1135 36 COG1309 AcrR, Transcriptional regulator Transcription 21225266 Common - ABC transporter membrane protein SCO6980 113 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 21223466 Common - DNA-binding protein SCO5095 101 COG1396 HipB, Predicted transcriptional regulators Transcription 21223676 Common - membrane protein SCO5313 9 None None None 21224741 Common - hypothetical protein SCO6435 12 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 21220881 Common - secreted protein SCO2415 45 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 21220328 Common - transcriptional regulator SCO1839 6 None None None 21220646 Common - hypothetical protein SCO2172 8 None None None 21220933 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein SCO2470 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 21218691 Common - secreted protein SCO0131 75 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 21218700 Nonpathogen - calcium-binding protein SCO0141 1 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 21219343 Common - DNA-binding protein SCO0822 27 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 21220267 Common - hypothetical protein SCO1775 153 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 21221716 Common - cobalt-precorrin-6x reductase SCO3283 45 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 21222057 Common - hypothetical protein SCO3642 7 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 21222071 Common - hypothetical protein SCO3656 8 None None None 21219718 Nonpathogen - hypothetical protein SCO1208 10 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 21223429 Common xseA exodeoxyribonuclease VII large subunit SCO5056 203 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 21225410 Common - transmembrane efflux protein SCO7128 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220291 Nonpathogen - small secreted protein SCO1800 1 None None None 21225278 Common - regulatory protein SCO6992 7 None None None 21225122 Common - ArsR-family transcriptional regulator SCO6830 156 COG0640 ArsR, Predicted transcriptional regulators Transcription 21225297 Common - membrane transport protein SCO7011 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21222170 Common - integral membrane protein SCO3759 8 None None None 21222223 Common - hypothetical protein SCO3813 4 None None None 21222875 Common - hypothetical protein SCO4489 12 None None None 21224346 Common - probable ABC-type transmembrane transport protein SCO6011 112 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 21224713 Common - DNA recombinase SCO6405 81 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 32141265 Common - hypothetical protein SCO5489 14 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21219947 Common - hypothetical protein SCO1445 48 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21221007 Common - Hit-family protein SCO2548 201 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 21223782 Nonpathogen - hypothetical hydrophilic protein SCO5422 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 21218873 Common - hypothetical protein SCO0326 9 None None None 21218933 Nonpathogen - hypothetical protein SCO0390 1 None None None 21222953 Common - NADH dehydrogenase subunit I SCO4570 193 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 21223506 Common - N-succinyldiaminopimelate aminotransferase SCO5136 231 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 21219030 Common - peptide synthetase SCO0492 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21224084 Common - protease SCO5738 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 21219984 Common carB carbamoyl phosphate synthase large subunit SCO1483 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 21222608 Nonpathogen - hypothetical protein SCO4212 2 None None None 21222265 Common - peptidyl-prolyl cis-trans isomerase SCO3856 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 21219041 Common - hypothetical protein SCO0503 35 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 21220993 Common - hypothetical protein SCO2533 55 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 21224815 Common - ABC transporter ATP-binding protein SCO6512 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21219506 Nonpathogen - hypothetical protein 2SCG202c SCO0989 1 None None None 21223976 Common - RNA polymerase sigma factor WhiG SCO5621 207 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21219162 Common - acetyltransferase SCO0630 66 COG3153 COG3153, Predicted acetyltransferase General function prediction only 21219915 Common - hypothetical protein SCO1412 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 32141186 Common - serine/threonine protein kinase SCO2973 112 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21218963 Common - two-component response regulator SCO0421 211 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223209 Common - glycine betaine-binding lipoprotein SCO4832 59 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 21218645 Common - hypothetical protein SCO0070 133 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21218992 Common - hypothetical protein SCO0451 95 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21223585 Common - anti-sigma factor SCO5217 16 None None None 21225846 Common - hypothetical protein SCO7582 60 COG0714 COG0714, MoxR-like ATPases General function prediction only 21221061 Common - integrase SCO2603 21 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 21221566 Common - fatty acid desaturase (membrane) SCO3128 68 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 21223647 Common kgd alpha-ketoglutarate decarboxylase SCO5281 194 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 21224272 Common - sigma factor SCO5934 35 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21224008 Common - aldehyde dehydrogenase SCO5657 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21219661 Common - ABC transporter SCO1148 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21220721 Nonpathogen - integral membrane protein SCO2251 2 None None None 21220861 Common - secreted protein SCO2394 7 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 32141320 Common - aminotransferase (fragment) SCO7034 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 21220834 Common - integral membrane protein SCO2366 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 21222528 Nonpathogen - integral membrane protein SCO4129 1 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 21222288 Common - ribonuclease P component SCO3881 10 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 21220575 Common - hypothetical protein SCO2095 52 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 21223361 Common - carbohydrate kinase SCO4988 132 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21223833 Common - oligopeptide transport integral membrane protein SCO5476 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21219253 Common - regulatory protein SCO0728 57 COG1309 AcrR, Transcriptional regulator Transcription 21225135 Nonpathogen - hypothetical protein SCO6843 2 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 21225427 Common - ketoreductase SCO7147 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21225420 Common - DNA-binding protein SCO7140 40 None None None 21224380 Nonpathogen - hypothetical protein SCO6049 1 None None None 21222367 Common - prephenate dehydratase SCO3962 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 32141104 Common - alcohol dehydrogenase (zinc-binding) SCO0259 208 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 21223256 Common - hypothetical protein 2SCK808 SCO4882 3 None None None 21218748 Common - oxidoreductase SCO0192 20 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21219503 Nonpathogen - integral membrane protein SCO0986 1 None None None 21220341 Common - cobyrinic acid a,c-diamide synthase SCO1852 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 21218862 Common - secreted protein SCO0314 43 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 21219444 Common - lysR-family transcriptional regulator SCO0925 192 COG0583 LysR, Transcriptional regulator Transcription 21225534 Nonpathogen - secreted protein SCO7257 1 None None None 21221881 Common - hypothetical protein SCO3456 34 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 21222897 Nonpathogen - hypothetical protein SCO4512 2 None None None 21220560 Common - hypothetical protein SCO2080 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 21224746 Common - hypothetical protein SCO6440 26 COG1891 COG1891, Uncharacterized protein conserved in archaea Function unknown 21225214 Common - hypothetical protein SCO6926 27 None None None 21224702 Common - integral membrane protein SCO6390 40 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21222674 Common - hypothetical protein SCO4281 174 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 21224315 Common - hypothetical protein SCO5978 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21224738 Common - peptide synthase SCO6431 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21225954 Common - tetR-family transcriptional regulator SCO7694 61 COG1309 AcrR, Transcriptional regulator Transcription 21220369 Common - secreted protein SCO1881 16 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 21222988 Nonpathogen - NADH dehydrogenase subunit NuoK2 SCO4605 6 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 21224530 Common - oxidoreductase SCO6206 75 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 21226035 Common - oxidoreductase SCO7784 61 COG0778 NfnB, Nitroreductase Energy production and conversion 32141301 Common - oxidoreductase SCO6434 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 21221349 Common - hypothetical protein SCO2902 236 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 21219158 Nonpathogen - hypothetical protein SCO0626 1 None None None 21222944 Common - NLP/P60 family protein SCO4561 49 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21219462 Nonpathogen - hypothetical protein SCO0943 1 None None None 21220389 Common - hypothetical hydrophilic protein SCO1902 4 None None None 21221927 Common - lacI-family transcriptional regulator SCO3506 126 COG1609 PurR, Transcriptional regulators Transcription 21223990 Nonpathogen - hypothetical protein SCO5639 7 None None None 21225511 Common - cytochrome C oxidase polypeptide I SCO7234 173 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 21223589 Common - polypeptide deformylase SCO5221 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 21223260 Common - sugar ABC transporter ATP-binding protein SCO4886 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 21219856 Nonpathogen - hypothetical protein SCO1350 1 None None None 21222382 Common - oxidoreductase SCO3978 133 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21218869 Common - carboxylesterase SCO0321 57 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 21219224 Common - integral membrane protein SCO0696 6 None None None 21220055 Common - acetyltransferase SCO1556 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21223714 Common - diaminopimelate decarboxylase SCO5353 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 21219894 Common - PTS system sugar phosphotransferase component IIA SCO1390 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 21222663 Common - transcriptional regulator SCO4270 47 COG1309 AcrR, Transcriptional regulator Transcription 21225504 Common - secreted protein SCO7227 219 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 21220388 Common - zinc-binding dehydrogenase SCO1901 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21222458 Common - alcohol dehydrogenase SCO4055 210 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21219133 Common - RNA polymerase sigma factor sig8 SCO0600 214 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21222912 Nonpathogen - integral membrane protein SCO4527 7 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 21220067 Common - oxidoreductase SCO1569 17 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21225173 Nonpathogen - hypothetical protein SCO6882 1 None None None 21222093 Nonpathogen - hypothetical protein SCO3680 1 None None None 21220206 Common - dehydrogenase SCO1711 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 21221230 Common - acyl-CoA dehydrogenase SCO2779 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21218884 Common - dehydrogenase SCO0339 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 21225932 Common - integral membrane protein SCO7672 6 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 21221058 Common - hypothetical protein SCO2600 42 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 21222940 Nonpathogen - hypothetical protein SCO4557 1 None None None 21220161 Common - hypothetical protein SCO1665 17 None None None 21221641 Common - transmembrane efflux protein SCO3206 177 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21223350 Common - tetR-family transcriptional regulator SCO4977 30 COG1309 AcrR, Transcriptional regulator Transcription 21221726 Nonpathogen - transferase SCO3294 1 None None None 21220601 Common - esterase/lipase SCO2123 56 COG1647 COG1647, Esterase/lipase General function prediction only 21221400 Common - hypothetical protein SCO2955 15 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21222117 Common - substrate-binding transport protein SCO3704 111 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 21223435 Nonpathogen - hypothetical protein SCO5063 2 None None None 21219966 Common - ribulose-phosphate 3-epimerase SCO1464 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 21220590 Common - hypothetical protein SCO2112 86 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 21222885 Common - dehydratase SCO4500 27 COG2030 MaoC, Acyl dehydratase Lipid metabolism 21221573 Common - acetyltransferase SCO3135 30 COG0456 RimI, Acetyltransferases General function prediction only 21220966 Common - ABC-transporter metal-binding lipoprotein SCO2505 176 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 21222297 Common - thioredoxin reductase (NADPH) SCO3890 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 21224522 Common - secreted protein SCO6198 4 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 21222480 Common - phosphoribosylformylglycinamidine synthase subunit I SCO4078 229 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 21224620 Nonpathogen - hypothetical protein SCO6302 1 None None None 21220143 Common - hypothetical protein SCO1647 16 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 21219554 Common - hypothetical protein SCO1038 6 None None None 21218895 Nonpathogen - hypothetical protein SCO0351 1 None None None 21222323 Common - hypothetical protein SCO3916 28 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 32141131 Common - regulatory protein SCO1108 30 COG0640 ArsR, Predicted transcriptional regulators Transcription 21220440 Common - iron sulphur binding protein SCO1955 48 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 21220278 Common - iron-siderophore uptake system transmembrane component SCO1786 160 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 21224686 Common - sugar transferase SCO6374 215 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21221124 Common - hypothetical protein SCO2668 12 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 21219281 Common - phosphatase SCO0757 170 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 21220392 Common - hypothetical protein SCO1905 15 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 21222123 Nonpathogen - large integral membrane protein SCO3710 1 None None None 21218653 Nonpathogen - hypothetical protein SCO0084 1 None None None 21220151 Common - lipoprotein oligopeptide binding protein SCO1655 185 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 21225961 Common - GntR-family transcriptional regulator SCO7702 108 COG2186 FadR, Transcriptional regulators Transcription 21222342 Common - integrase /recombinase SCO3937 19 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 21224529 Common - dehydrogenase SCO6205 190 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 21221920 Common - secreted protein SCO3498 11 None None None 21219075 Common - probable sugar transport membrane protein SCO0540 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21225031 Nonpathogen - hypothetical protein SCO6737 1 None None None 21225153 Nonpathogen - hypothetical protein SCO6862 1 None None None 21221075 Common - ATP-dependent Clp protease proteolytic subunit SCO2618 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21221592 Nonpathogen - hypothetical protein SCO3155 1 None None None 21223003 Common - sporulation-related protein SCO4620 91 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21218816 Common - hydroxylase SCO0265 46 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21219642 Common - integral membrane protein SCO1128 10 None None None 21224781 Common - hypothetical protein SCO6477 66 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 21223016 Common - hydrolase SCO4634 55 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 21218995 Common - binding-protein dependent transport protein SCO0454 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222330 Nonpathogen - hypothetical protein SCO3924 1 None None None 21224393 Common - ABC transporter permease protein SCO6063 72 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 21222098 Common - hypothetical protein SCO3685 4 None None None 21224004 Nonpathogen - integral membrane protein SCO5653 1 None None None 21224106 Common - DNA glycosylase SCO5760 175 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 21223852 Common - small membrane hydrophobic protein SCO5496 4 None None None 21222234 Common - ABC-transporter ATP-binding component SCO3824 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 32141341 Nonpathogen - cyclase SCO7700 4 None None None 21224664 Common - hypothetical protein SCO6351 31 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221307 Nonpathogen - membrane protein SCO2857 1 None None None 21219121 Common - sensor kinase SCO0588 11 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21220088 Common - 3-hydroxybutyryl-CoA dehydrogenase SCO1591 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21225968 Common - MarR-family transcriptional regulator SCO7709 17 COG1846 MarR, Transcriptional regulators Transcription 21222349 Common - putative aminotransferase SCO3944 241 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 21222902 Nonpathogen - hypothetical protein SCO4517 1 None None None 21223883 Common - transcriptional regulator SCO5528 67 COG1309 AcrR, Transcriptional regulator Transcription 21218942 Common - hypothetical protein SCO0399 17 COG2327 WcaK, Uncharacterized conserved protein Function unknown 21220210 Common - gntR-family transcriptional regulator SCO1716 112 COG2188 PhnF, Transcriptional regulators Transcription 21223178 Common - isobutiryl CoA mutase, small subunit SCO4800 109 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 21219778 Common - pyruvate dehydrogenase alpha subunit SCO1270 158 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 21221266 Common - hypothetical protein SCO2816 116 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21222195 Nonpathogen - hypothetical protein SCO3784 1 None None None 21224228 Common - 3-oxoacyl-[acyl-carrier-protein] synthase II SCO5886 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21219482 Common - hypothetical protein SCO0964 31 None None None 21220554 Common lspA lipoprotein signal peptidase SCO2074 16 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 21223576 Common - monophosphatase SCO5208 197 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 21223145 Common - transcriptional regulator SCO4766 189 COG0583 LysR, Transcriptional regulator Transcription 21224357 Common - hypothetical protein SCO6025 4 None None None 21220219 Common - secreted hydrolase SCO1725 15 None None None 32141233 Common - hypothetical protein SCO4346 8 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 21224382 Common - iron-sulfur binding oxidoreductase SCO6051 74 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 32141212 Common - ATP-dependent protease ATP-binding subunit SCO3661 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 21224790 Common - transport associated protein SCO6486 35 COG2362 DppA, D-aminopeptidase Amino acid transport and metabolism 21223768 Common - hypothetical protein SCO5408 47 COG2013 COG2013, Uncharacterized conserved protein Function unknown 21225719 Common - secreted protein SCO7450 13 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 21222372 Nonpathogen - integral membrane protein SCO3968 1 None None None 21225837 Common - anti-sigma factor antagonist SCO7573 62 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21222109 Common - transcriptional regulator SCO3696 153 COG0640 ArsR, Predicted transcriptional regulators Transcription 21221429 Nonpathogen - integral membrane protein SCO2985 1 None None None 21220623 Common - aminotransferase SCO2146 234 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 21222694 Common - DNA-binding protein SCO4301 6 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 21224160 Common - hypothetical protein SCO5816 3 None None None 21222216 Nonpathogen - hypothetical protein SCO3806 4 None None None 21225639 Nonpathogen - hypothetical protein SCO7365 1 None None None 21224221 Common - polyketide synthase RedX SCO5878 208 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21225904 Common - hypothetical protein SCO7643 13 None None None 21224241 Common - probable membrane protein SCO5900 43 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21222208 Common - integral membrane protein SCO3797 160 COG0628 PerM, Predicted permease General function prediction only 21221275 Common - hypothetical protein SCO2825 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 21224799 Common - dehydrogenase SCO6496 218 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 21222021 Common - hypothetical protein SCO3605 4 None None None 21224167 Nonpathogen - integral membrane protein SCO5823 1 None None None 21223824 Common - hydrolase SCO5466 34 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 21219023 Common - tetR-family transcriptional regulator SCO0485 96 COG1309 AcrR, Transcriptional regulator Transcription 21221002 Common - 5-dehydro-4-deoxyglucarate dehydratase SCO2543 221 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 21225780 Nonpathogen - integral membrane protein SCO7514 3 None None None 21221999 Common - secreted protein SCO3582 61 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 21223262 Common - sugar ABC transporter integral membrane protein SCO4888 129 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 21223804 Common - hypothetical protein SCO5446 47 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 21223538 Common - ATP-binding protein SCO5169 16 None None None 21224608 Common - secreted oxidoreductase SCO6289 100 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 21224214 Common - turgor pressure sensor SCO5871 217 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 21219874 Common - two component system histidine kinase SCO1369 130 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21219409 Common - LysR-family transcriptional regulatory protein SCO0889 174 COG0583 LysR, Transcriptional regulator Transcription 21221155 Common - tyrosinase (monophenol monooxygenase) SCO2700 16 None None None 21220791 Common - integral membrane protein SCO2323 8 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 21224578 Common - ABC transport system sugar binding lipoprotein SCO6257 64 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21222159 Common - integral membrane protein SCO3747 5 None None None 21221658 Common - ABC transporter integral membrane protein SCO3223 7 None None None 21222907 Nonpathogen - hypothetical protein SCO4522 1 None None None 21222014 Common - hypothetical protein SCO3598 24 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 21222337 Nonpathogen - hypothetical protein SCO3931 1 None None None 21220816 Common - secreted protein SCO2348 24 None None None 21224595 Common - secreted protein SCO6276 22 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21225754 Common - ROK-family transcriptional regulator SCO7486 149 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21220337 Common - cobyric acid synthase SCO1848 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 21221753 Common - hypothetical protein SCO3322 67 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 21223723 Common - hypothetical protein 2SC6G507 SCO5363 13 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 32141205 Common - hypothetical protein SCO3465 121 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21225529 Common - regulatory protein SCO7252 6 None None None 21221673 Common - hypothetical protein SCO3240 3 None None None 21221571 Common - MarR-family regulator SCO3133 88 COG1846 MarR, Transcriptional regulators Transcription 21223320 Common - nitrate reductase alpha chain NarG3 SCO4947 134 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 21223694 Common - hypothetical protein SCO5333 6 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 21221141 Nonpathogen - luxR-family transcriptional regulator SCO2686 6 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220694 Common - iron-sulfur oxidoreductase (secreted protein) SCO2222 116 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 21220598 Common - two-component system regulator SCO2120 188 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223557 Common - ATP-dependent DNA helicase SCO5188 228 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 21220403 Common - transferase SCO1916 35 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 32141338 Common - LysR-family transcriptional regulator SCO7603 163 COG0583 LysR, Transcriptional regulator Transcription 21224194 Common - hypothetical protein SCO5850 60 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 21221919 Common - polyguluronate lyase precursor SCO3497 6 None None None 32141252 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase SCO5058 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 21223359 Common - D-aminoacylase SCO4986 56 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 21219286 Nonpathogen - protease inhibitor protein SCO0762 1 None None None 21218630 Nonpathogen - membrane-associated oxidoreductase SCO0055 5 None None None 21220339 Common - chelatase SCO1850 76 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 21221495 Common - secreted esterase SCO3053 23 None None None 21221974 Common - integral membrane protein SCO3555 3 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 21220078 Nonpathogen - hypothetical protein SCO1581 1 None None None 21222787 Common - ABC transport system ATP-binding protein SCO4397 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21220828 Common - hypothetical protein SCO2360 115 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21223634 Common - hypothetical protein 2SC7G1129c SCO5267 8 None None None 21218715 Common - oxidoreductase SCO0158 190 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 21221943 Common - transcriptional regulator SCO3522 46 COG0640 ArsR, Predicted transcriptional regulators Transcription 21224115 Common recA recombinase A SCO5769 242 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 21222166 Common - ABC transport system ATP binding protein SCO3755 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21224919 Common - hypothetical protein SCO6621 35 COG1520 COG1520, FOG: WD40-like repeat Function unknown 31340550 Nonpathogen - permease SCO1854 1 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 32141115 Common - secreted beta-mannosidase SCO0554 24 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 21223531 Common - integral membrane protein SCO5162 151 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 21223658 Common - oxygenase subunit SCO5293 19 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21219181 Nonpathogen - gas vesicle synthesis protein SCO0651 7 None None None 21220360 Common - IclR-family transcriptional regulator SCO1872 124 COG1414 IclR, Transcriptional regulator Transcription 21221824 Common - integral membrane lysyl-tRNA synthetase SCO3397 48 COG2898 COG2898, Uncharacterized conserved protein Function unknown 21226005 Common - hypothetical protein SCO7748 93 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225944 Common - hypothetical protein SCO7684 5 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 21224629 Common - integral membrane protein SCO6311 4 None None None 21220076 Common - acetylglutamate kinase SCO1578 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 21219197 Common - secreted protein SCO0667 51 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 21225609 Common - trehalose synthase SCO7334 172 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21218737 Common - hypothetical protein SCO0180 18 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21220177 Common - zinc-binding alcohol dehydrogenase SCO1682 195 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21222378 Common - hypothetical protein SCO3974 8 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 21223580 Common - 3-phosphoshikimate 1-carboxyvinyltransferase SCO5212 227 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 21224087 Nonpathogen - hypothetical protein SCO5741 1 None None None 32141128 Common - secreted protein SCO0974 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21219932 Common - chitinase (secreted protein) SCO1429 39 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 21218599 Nonpathogen - hypothetical protein SCO0017 1 None None None 21225764 Common - transcriptional regulator SCO7497 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21221135 Nonpathogen - lipoprotein SCO2679 1 None None None 21221288 Common - secreted endoglucanase SCO2838 17 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 21224630 Common - transcriptional regulator SCO6312 118 COG1309 AcrR, Transcriptional regulator Transcription 21219954 Nonpathogen - hypothetical protein SCO1452 9 None None None 21222274 Common - hypothetical protein SCO3866 60 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 21224752 Common - hypothetical protein SCO6446 5 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 21224674 Common - integral membrane protein SCO6361 8 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 21225245 Nonpathogen - membrane protein SCO6958 1 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 21219834 Nonpathogen - hypothetical protein SCO1328 1 None None None 21223392 Common - secreted protein SCO5019 6 COG1430 COG1430, Uncharacterized conserved protein Function unknown 21220223 Nonpathogen - hypothetical protein SCO1729 4 COG3153 COG3153, Predicted acetyltransferase General function prediction only 21220982 Nonpathogen - hypothetical protein SCO2521 2 None None None 21224952 Common - hypothetical protein SCO6656 139 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21224373 Common - hypothetical protein SCO6042 37 COG3253 COG3253, Uncharacterized conserved protein Function unknown 21223608 Common - hypothetical protein SCO5241 81 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 21224350 Common - hypothetical protein SCO6018 2 None None None 32141096 Common - transposase SCO0005 35 None None None 21220588 Common - eukaryotic-type serine/threonine protein kinase SCO2110 164 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21221473 Common - hypothetical protein SCO3030 18 None None None 21223216 Common - secreted protein SCO4840 11 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 21221439 Common - ABC transporter integral membrane protein SCO2995 121 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 21220833 Common - hypothetical protein SCO2365 18 COG4110 COG4110, Uncharacterized protein involved in stress response General function prediction only 21225542 Common - hypothetical protein SCO7265 9 None None None 21222418 Nonpathogen - hypothetical protein 2SC10A719 SCO4015 1 None None None 21219361 Common - marR-family transcriptional regulator SCO0840 29 COG1846 MarR, Transcriptional regulators Transcription 21219666 Common - acyl-CoA thioesterase II SCO1153 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 21222799 Common - anti anti sigma factor SCO4410 30 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21224328 Nonpathogen - secreted protein SCO5991 1 None None None 21221806 Common - hypothetical protein SCO3377 21 COG3682 COG3682, Predicted transcriptional regulator Transcription 21218857 Common - amide hydrolase SCO0309 63 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21222408 Common - RNA polymerase sigma factor SCO4005 130 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21226093 Nonpathogen - DNA-binding protein SCO7844 2 None None None 21224858 Common - transmembrane protein SCO6556 56 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 21221342 Common - integral membrane transport protein SCO2895 21 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 21219252 Nonpathogen - hypothetical protein 3SC5B705c SCO0727 1 None None None 21220780 Common - secreted protein SCO2312 12 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 21223702 Nonpathogen - SpdA2 protein SCO5341 4 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 21220618 Nonpathogen - small secreted hydrophilic protein SCO2141 1 None None None 21221560 Nonpathogen - hypothetical protein SCO3121 1 None None None 21225558 Common - ATP-dependent Clp protease proteolytic subunit 1 SCO7281 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21221879 Nonpathogen - ABC-transporter membrane protein SCO3454 4 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 21223123 Common acpS 4'-phosphopantetheinyl transferase SCO4744 16 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 21221938 Common - ATP-binding protein SCO3517 8 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 21223204 Common - malate dehydrogenase SCO4827 76 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 21219448 Common - hypothetical protein SCO0929 12 None None None 21222652 Nonpathogen - hydrolytic protein SCO4257 4 None None None 21223505 Common - ferredoxin SCO5135 146 COG1146 COG1146, Ferredoxin Energy production and conversion 21219916 Nonpathogen - hypothetical protein SCO1413 1 None None None 21222864 Common - merR-family transcriptional regulatory protein SCO4477 18 COG0789 SoxR, Predicted transcriptional regulators Transcription 32141264 Common - muramoyl-pentapeptide carboxypeptidase SCO5467 16 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 32141119 Common - transmembrane efflux protein SCO0680 160 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21218990 Common - secreted solute-binding lipoprotein SCO0449 74 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219205 Common - hypothetical protein SCO0675 76 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21222593 Common - MarR-family regulator SCO4197 6 COG1846 MarR, Transcriptional regulators Transcription 21224870 Common - secreted solute binding protein SCO6569 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21221185 Common - integral-membrane protein SCO2732 20 COG5500 COG5500, Predicted integral membrane protein Function unknown 21223793 Common - two-component response regulator SCO5434 65 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 21220195 Common - hypothetical protein SCO1700 11 COG4298 COG4298, Uncharacterized protein conserved in bacteria Function unknown 21223152 Common - nucleotide-sugar dehydrogenase SCO4773 201 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 21223944 Nonpathogen - hypothetical protein SCO5589 3 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21223906 Common - hypothetical protein SCO5551 8 None None None 21218782 Common - short chain dehydrogenase SCO0229 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21220058 Common - ABC transporter ATP-binding protein SCO1559 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 21221954 Nonpathogen - hypothetical protein SCO3533 1 None None None 21221354 Common - PTS transmembrane component SCO2907 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 21221367 Common - secreted protease SCO2920 22 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 21221084 Common - ribose-5-phosphate isomerase B SCO2627 126 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 21225407 Common - hypothetical protein SCO7125 29 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21220811 Common - acetyltransferase SCO2343 9 COG3153 COG3153, Predicted acetyltransferase General function prediction only 21224616 Common - 3-hydroxyacyl-CoA dehydrogenase SCO6297 131 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21219799 Nonpathogen - secreted protein SCO1292 2 None None None 21221355 Common - hypothetical protein SCO2908 89 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 32141165 Common - integral membrane efflux protein SCO2310 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21223755 Common - ABC transporter ATP-binding subunit SCO5395 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21224914 Common - secreted protein SCO6616 21 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21219218 Common - oxidoreductase, iron-sulphur binding subunit SCO0689 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 21224177 Common - hypothetical protein SCO5833 2 None None None 21224459 Nonpathogen - hypothetical protein SCO6132 1 None None None 21223422 Common - hypothetical protein SCO5049 46 COG0778 NfnB, Nitroreductase Energy production and conversion 21221409 Common - lysR-family transcriptional regulator SCO2964 177 COG0583 LysR, Transcriptional regulator Transcription 21222971 Nonpathogen - hypothetical protein SCO4588 1 None None None 21222147 Nonpathogen - secreted protein SCO3735 1 COG5373 COG5373, Predicted membrane protein Function unknown 21221111 Nonpathogen - hypothetical protein SCO2654 3 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 21224553 Common - probable sugar transport system sugar-binding lipoprotein SC2H413c SCO6231 29 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21221067 Nonpathogen - rod shape-determining protein SCO2609 1 None None None 21221222 Common - hypothetical protein SCO2771 3 None None None 21221272 Common - decarboxylase SCO2822 35 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 21224656 Nonpathogen - hypothetical protein SCO6343 1 None None None 21219082 Common - acyltransferase SCO0547 80 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 32141152 Common - hypothetical protein SCO1987 55 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21219792 Common - aminotransferase (secreted protein) SCO1284 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 21222276 Nonpathogen - hypothetical protein SCO3868 1 None None None 21220253 Common - cytidylate kinase SCO1760 203 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 21223099 Common rpsE 30S ribosomal protein S5 SCO4719 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 21224179 Common - ATP/GTP-binding protein SCO5835 124 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 21224320 Common - fatty acid-CoA ligase SCO5983 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 21219435 Common - hypothetical protein, SCM1004c SCO0916 6 None None None 21225974 Common - hypothetical protein SCO7715 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21224727 Common - DNA-binding protein SCO6420 4 None None None 21219702 Common - marR-family transcriptional regulator SCO1191 27 COG1846 MarR, Transcriptional regulators Transcription 21221374 Common - 4-hydroxyphenylpyruvate dioxygenase SCO2927 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 21221763 Common - hypothetical protein SCO3332 4 None None None 21225878 Common - AbaA-like protein SCO7616 6 None None None 21221853 Common - hypothetical protein SCO3426 60 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 32141298 Nonpathogen - integral membrane protein SCO6333 1 None None None 21224995 Common - beta-ketoadipyl-CoA thiolase SCO6701 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21225203 Nonpathogen - hypothetical protein SCO6915 1 None None None 21218676 Nonpathogen - hypothetical protein SCO0112 1 None None None 21224990 Common - regulatory protein SCO6696 21 COG3899 COG3899, Predicted ATPase General function prediction only 21219170 Common - integral membrane protein SCO0639 8 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 21223306 Common hutH histidine ammonia-lyase SCO4932 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 21221847 Common - aldehyde dehydrogenase SCO3420 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21225883 Common - hypothetical protein SCO7621 5 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 21222798 Common - RNA polymerase sigma factor SCO4409 41 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21218914 Common - DNA-binding protein (secreted protein) SCO0370 8 None None None 21221399 Common - RNA polymerase sigma factor SigL SCO2954 138 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21222613 Common - hypothetical protein SCO4217 48 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 21219396 Common - ArsR-family transcriptional regulatory protein SCO0875 38 COG0640 ArsR, Predicted transcriptional regulators Transcription 21222754 Common - two component system response regulator SCO4363 179 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221390 Common - sugar transporter membrane protein SCO2945 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21225453 Nonpathogen - hypothetical protein SCO7174 1 None None None 21224824 Common - hypothetical protein SCO6522 9 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 21223033 Nonpathogen - lipoprotein SCO4651 2 None None None 21224945 Nonpathogen - hypothetical protein SCO6648 13 None None None 21220756 Common - oxidoreductase SCO2287 235 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21221890 Common - transposase SCO3466 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21221011 Common - hypothetical protein SCO2552 153 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 21220918 Common - integral membrane protein SCO2454 36 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225062 Common - probable aminotransferase SCO6769 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 21223104 Common - translational initiation factor IF1 SCO4725 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 21225222 Common - hypothetical protein SCO6935 9 None None None 21225296 Common - alpha glucosidase SCO7010 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21225006 Common - copper oxidase SCO6712 74 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 21223444 Common - hydroxylacyl-CoA dehydrogenase SCO5072 147 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21224719 Common - hydrolase SCO6411 183 COG0388 COG0388, Predicted amidohydrolase General function prediction only 21225228 Nonpathogen - hypothetical protein SCO6941 1 None None None 21225686 Nonpathogen - hypothetical protein SCO7416 1 None None None 21221688 Nonpathogen - SpdB protein SCO3255 1 None None None 21222389 Nonpathogen - hypothetical protein SCO3985 1 None None None 21225020 Common - endonuclease SCO6726 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 21222426 Common - integral membrane protein SCO4023 19 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 21223454 Common - actinorhodin transporter SCO5083 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220116 Common - glycine betaine transport system permease protein SCO1620 148 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 21220633 Common - cytochrome c oxidase subunit II SCO2156 135 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 21220873 Common - sugar transport permease SCO2406 105 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 21219813 Common - hypothetical protein SCO1306 32 COG0714 COG0714, MoxR-like ATPases General function prediction only 21221129 Nonpathogen - hypothetical protein SCO2673 1 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 21226061 Nonpathogen - membrane protein SCO7811 2 None None None 21220379 Nonpathogen - integral membrane efflux protein SCO1892 5 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 21218726 Common - hypothetical protein SCO0169 158 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 21221314 Common - regulatory protein SCO2865 7 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 21224217 Common - hypothetical protein SCO5874 15 None None None 21220032 Nonpathogen - hypothetical protein SCO1532 2 None None None 21221639 Common - hypothetical protein SCO3204 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 21223858 Common - integral membrane export protein SCO5502 31 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21222649 Nonpathogen - hypothetical protein SCO4254 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 21223805 Common - neutral zinc metalloprotease SCO5447 50 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 21219270 Common - serine/threonine protein kinase (putative secreted protein) SCO0746 35 COG3391 COG3391, Uncharacterized conserved protein Function unknown 32141200 Common - hypothetical protein SCO3350 2 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225142 Nonpathogen - hypothetical protein SCO6851 1 None None None 21226084 Nonpathogen - hypothetical protein SCO7835 1 None None None 21223873 Common - transcriptional regulator SCO5517 9 COG1309 AcrR, Transcriptional regulator Transcription 21222594 Common - DNA-binding protein SCO4198 37 COG1396 HipB, Predicted transcriptional regulators Transcription 21224202 Common - integral membrane protein SCO5858 26 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224143 Common - secreted protein SCO5798 12 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 32141318 Common - acetolactate synthase SCO6975 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 21222506 Nonpathogen - hypothetical protein SCO4105 1 None None None 21224257 Nonpathogen - hypothetical protein SCO5918 1 None None None 21219416 Common - oxidoreductase SCO0896 78 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 21224147 Common - ATP-dependent helicase SCO5802 133 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 21224425 Common - lipoprotein SCO6096 106 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 21225315 Common - binding-protein-dependent transport protein SCO7030 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21220090 Common - transcriptional regulator SCO1593 4 None None None 21224501 Common - hypothetical protein SCO6176 37 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 21220465 Nonpathogen - hypothetical protein SCO1982 1 None None None 21225383 Common - dehydrogenase SCO7101 156 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 21219323 Common - cytochrome P450 SCO0801 71 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21222397 Nonpathogen - hypothetical protein SCO3994 1 None None None 21219994 Nonpathogen - secreted protein SCO1493 1 COG5602 SIN3, Histone deacetylase complex, SIN3 component Chromatin structure and dynamics 21225069 Common - hypothetical protein SCO6776 104 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 32141239 Common - hypothetical protein SCO4494 82 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 21224442 Common - ROK family transcriptional regulator SCO6115 165 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21221540 Nonpathogen - lipoprotein SCO3101 2 None None None 21218880 Common - secreted protein SCO0335 12 None None None 21222437 Common - RNA polymerase sigma factor SCO4034 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21220700 Common - alpha-glucosidase SCO2228 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21222316 Common rplI 50S ribosomal protein L9 SCO3909 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 21224930 Common - transcriptional regulator SCO6633 13 COG3899 COG3899, Predicted ATPase General function prediction only 21221718 Common - secreted protein SCO3286 32 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 21223117 Common - pantothenate kinase SCO4738 79 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 21223272 Common - tetR-family transcriptional regulator SCO4898 64 COG1309 AcrR, Transcriptional regulator Transcription 21221048 Common - glycosyl transferase SCO2589 193 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 21225626 Common - membrane protein SCO7352 7 COG4270 COG4270, Predicted membrane protein Function unknown 21224508 Common - transferase SCO6184 15 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21219909 Common - heat shock protein (hsp90-family) SCO1405 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 21222441 Common - deaminase SCO4038 208 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 21219355 Nonpathogen - hypothetical protein SCO0834 1 None None None 21220136 Common - hypothetical protein SCO1640 16 None None None 21223081 Common rpsJ 30S ribosomal protein S10 SCO4701 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 21219453 Nonpathogen - integral membrane protein SCO0934 1 COG1470 COG1470, Predicted membrane protein Function unknown 21223666 Nonpathogen - hypothetical protein SCO5303 1 COG4907 COG4907, Predicted membrane protein Function unknown 21222769 Common - hypothetical protein SCO4379 35 None None None 21221523 Nonpathogen - hypothetical protein SCO3082 3 None None None 21222257 Common - serine/threonine protein kinase SCO3848 167 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21223490 Common - peptide transport system ATP-binding protein SCO5120 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21220375 Common - dihydroxy-acid dehydratase SCO1888 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 21221250 Common - secreted sugar hydrolase SCO2799 24 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 21221259 Nonpathogen - secreted protein SCO2808 1 None None None 21219688 Common - gntR-famly transcriptional regulator SCO1177 106 COG2186 FadR, Transcriptional regulators Transcription 21224643 Nonpathogen - hypothetical protein SCO6329 1 None None None 21219729 Nonpathogen - integral membrane protein SCO1219 1 COG2056 COG2056, Predicted permease General function prediction only 21223955 Common - hypothetical protein SCO5600 15 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 32141223 Common - transposase SCO4065 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 21225341 Common - integral membrane protein SCO7058 4 None None None 21222570 Common - hypothetical protein SCO4173 5 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 21219767 Common - two-component system sensor kinase SCO1259 60 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21225433 Common - sugar transporter SCO7153 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220097 Common infC translation initiation factor IF-3 SCO1600 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 21225623 Nonpathogen - hypothetical protein SCO7349 1 None None None 21220645 Common - secreted protease SCO2171 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21225181 Nonpathogen - secreted protein SCO6890 1 None None None 21223987 Common - transcriptional regulator SCO5636 128 COG2188 PhnF, Transcriptional regulators Transcription 21221140 Common - ATP-binding protein SCC61A06c SCO2685 9 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 21219699 Common - secreted cellulose binding protein SCO1188 26 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 21223615 Common - hypothetical protein SCO5248 4 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 21225702 Nonpathogen - secreted extracellular small neutral protease SCO7432 3 None None None 21222305 Common - hypothetical protein SCO3898 30 None None None 21222547 Nonpathogen - ABC transport system transmembrane protein SCO4149 1 None None None 21222762 Nonpathogen - hypothetical protein SCO4372 1 None None None 21221845 Common - ABC transporter ATP-binding component SCO3418 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21223847 Common - hypothetical protein SCO5491 132 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 21222617 Nonpathogen - hypothetical protein SCO4221 2 None None None 21223682 Common - whiE protein II SCO5319 18 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21219146 Common - arginine deiminase SCO0613 51 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 21225344 Common - marR-family transcriptional regulator SCO7061 58 COG1846 MarR, Transcriptional regulators Transcription 21220248 Nonpathogen - conserved hypothetical protein 2SCI3408c SCO1755 1 None None None 21225397 Common - hypothetical protein SCO7115 9 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 21219970 Common - serine/threonine protein kinase SCO1468 84 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21219385 Common - probable ECF-family sigma factor SCO0864 154 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220916 Common - two-component sensor histidine kinase SCO2452 14 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21226074 Nonpathogen - hypothetical protein SCO7825 1 None None None 21223020 Common - hypothetical protein SCO4638 55 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21224434 Common - regulatory protein SCO6105 80 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 21220015 Common secF preprotein translocase subunit SecF SCO1515 215 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 21225497 Common - hypothetical protein SCO7220 29 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221095 Nonpathogen - hypothetical protein SCO2638 1 None None None 21224457 Common - hypothetical protein SCO6130 8 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21223471 Common - gntR-family regulatory protein SCO5100 44 COG2188 PhnF, Transcriptional regulators Transcription 161353684 Common - hypothetical protein SCO0101 8 None None None 21219496 Nonpathogen - hypothetical protein SCO0979 1 None None None 21222048 Common - ABC transporter ATP-binding protein SCO3633 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21220928 Common - RNA polymerase principal sigma factor SCO2465 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 21223520 Nonpathogen - hypothetical protein SCO5151 1 None None None 21219208 Nonpathogen - hypothetical protein SCO0678 1 None None None 21220109 Common - aldehyde dehydrogenase SCO1612 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21221612 Common - acetyltransferase SCO3175 20 COG3393 COG3393, Predicted acetyltransferase General function prediction only 21221601 Common - integral membrane protein SCO3164 51 COG5617 COG5617, Predicted integral membrane protein Function unknown 21224639 Common - hydrolase SCO6324 139 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 21221065 Common - Sfr protein SCO2607 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 21223936 Common - prokaryotic docking protein SCO5580 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 21221455 Common - two-component system histidine kinase SCO3012 202 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21223474 Common - regulatory protein SCO5103 8 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21224348 Common - cationic amino acid transporter SCO6014 170 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21223869 Common ilvH acetolactate synthase 3 regulatory subunit SCO5513 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 21218936 Common - transferase SCO0393 102 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 21220768 Common - hypothetical protein SCO2299 136 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21220671 Common - glutamine synthetase I SCO2198 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 21223074 Common - hypothetical protein SCO4694 2 None None None 21221096 Common - RNA polymerase sigma factor SCO2639 79 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21219245 Nonpathogen - hypothetical protein SCO0719 4 None None None 21222637 Nonpathogen - hypothetical protein SCO4242 1 None None None 21221448 Common - preprotein translocase subunit SecA SCO3005 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 21219546 Common - hypothetical protein SCO1030 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21225467 Common - secreted peptidase SCO7188 137 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21218828 Common - MutT domain containing protein SCO0278 17 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21221372 Common - oxidoreductase subunit SCO2925 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21222055 Common - two-component system regulator SCO3640 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219010 Common - hydrolase SCO0470 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21219498 Common - DNA-binding protein SCO0981 50 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 21219521 Nonpathogen - hypothetical protein 2SCG217c SCO1004 1 None None None 21220203 Nonpathogen - hypothetical protein SCO1708 1 None None None 21220636 Nonpathogen - hypothetical protein SCO2159 1 None None None 21220272 Common - DNA repair protein SCO1780 197 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 21219018 Common - hypothetical protein SCO0478 12 None None None 21219250 Common - hypothetical protein 3SC5B703 SCO0725 3 None None None 21224364 Common - hydrolase SCO6032 179 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21223488 Common - peptide transport system integral membrane protein SCO5118 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21221463 Common - integral membrane protein SCO3020 37 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 21225273 Common - hypothetical protein SCO6987 9 COG3548 COG3548, Predicted integral membrane protein Function unknown 21220682 Common - glutamine synthetase SCO2210 110 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 21220825 Common - hypothetical protein SCO2357 5 None None None 21225211 Nonpathogen - hypothetical protein SCO6923 1 None None None 21223238 Nonpathogen - hypothetical protein SCO4863 1 None None None 21224510 Common - phosphoheptose isomerase SCO6186 112 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 21223048 Common - two-component system sensor kinase SCO4667 23 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220672 Nonpathogen - integral membrane protein SCO2199 1 None None None 21219264 Common - short chain dehydrogenase SCO0739 40 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21220955 Common - hypothetical protein SCO2492 3 None None None 21221210 Common - beta-N-acetylglucosaminidase (secreted protein) SCO2758 183 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21222202 Common - hypothetical protein SCO3791 6 COG5373 COG5373, Predicted membrane protein Function unknown 21225392 Common - ferredoxin SCO7110 124 COG1146 COG1146, Ferredoxin Energy production and conversion 21225588 Nonpathogen - hypothetical protein SCO7312 1 None None None 21221985 Common - hydrolase SCO3566 141 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221290 Common - LysR-family transcriptional regulatory protein SCO2840 147 COG0583 LysR, Transcriptional regulator Transcription 21225727 Common - membrane protein SCO7458 12 None None None 21223385 Nonpathogen - integral membrane protein SCO5012 1 None None None 21220468 Nonpathogen - integral membrane protein SCO1985 1 COG1289 COG1289, Predicted membrane protein Function unknown 21220734 Common - hypothetical protein SCO2265 4 None None None 21223566 Common - hypothetical protein SCO5197 20 COG2013 COG2013, Uncharacterized conserved protein Function unknown 21220931 Common dnaG DNA primase SCO2468 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 21224465 Common - sensor kinase SCO6139 56 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220875 Common - aminotransferase SCO2408 224 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 21221468 Common - mannose-6-phosphate isomerase SCO3025 42 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 21223779 Common - thioredoxin SCO5419 228 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 21219785 Nonpathogen - hypothetical protein 2SCG1824 SCO1277 1 None None None 21220505 Common - chitosanase (secreted protein) SCO2024 4 None None None 21219727 Common - sensor kinase SCO1217 108 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 21221777 Common - hypothetical protein SCO3347 27 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21225854 Common - regulatory protein SCO7591 89 COG0583 LysR, Transcriptional regulator Transcription 21219025 Common - MarR-family transcriptional regulator SCO0487 25 COG1846 MarR, Transcriptional regulators Transcription 21222169 Common - fatty acid desaturase SCO3758 32 COG3239 DesA, Fatty acid desaturase Lipid metabolism 21218920 Nonpathogen - hypothetical protein SCO0377 1 None None None 21224583 Common - helicase SCO6262 141 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 21219736 Common - DNA-binding protein SCO1227 3 COG1396 HipB, Predicted transcriptional regulators Transcription 21225917 Nonpathogen - hypothetical protein SCO7656 1 None None None 21219989 Common - pyrimidine regulatory protein PyrR SCO1488 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 21220723 Common - hypothetical protein SCO2253 6 None None None 21224976 Common - oxidoreductase alpha subunit SCO6680 72 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 21218931 Common - hypothetical protein SCO0388 24 None None None 21219823 Common - integral membrane protein SCO1316 167 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21224470 Common - transcriptional regulator SCO6144 10 COG1309 AcrR, Transcriptional regulator Transcription 21218841 Common - binding protein dependent transport protein SCO0291 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222788 Common - hypothetical protein SCO4398 5 None None None 21223375 Nonpathogen - hypothetical protein SCO5002 1 None None None 21220853 Common - hypothetical protein SCO2386 18 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 21222724 Common - integral membrane ATPase SCO4332 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 21221360 Common - hypothetical protein SCO2913 32 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 21219484 Common - dehydratase SCO0966 36 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21218792 Common - hypothetical protein SCO0239 2 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21222453 Common - acetyltransferase SCO4050 29 None None None 21225164 Nonpathogen - hypothetical protein SCO6873 1 None None None 21219008 Common - hypothetical protein SCO0468 143 COG1741 COG1741, Pirin-related protein General function prediction only 21222781 Common - hypothetical protein SCO4391 149 COG1733 COG1733, Predicted transcriptional regulators Transcription 21218905 Common - hypothetical protein SCO0361 35 COG3970 COG3970, Fumarylacetoacetate (FAA) hydrolase family protein General function prediction only 21219257 Common - secreted protease SCO0732 11 None None None 21219138 Common - araC-family transcriptional regulator SCO0605 156 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21224735 Common - secreted protein SCO6428 62 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 21221420 Nonpathogen - hypothetical protein SCO2976 1 None None None 21224694 Common - secreted protein SCO6382 12 COG2367 PenP, Beta-lactamase class A Defense mechanisms 21225634 Common - hypothetical protein SCO7360 120 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 21224307 Nonpathogen - hypothetical protein SCO5970 1 None None None 21220183 Nonpathogen - hypothetical protein SCO1688 1 None None None 21224537 Common - permease SCO6214 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 21221337 Common - hypothetical protein SCO2888 31 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 21221654 Common - lipase (secreted protein) SCO3219 11 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 21222102 Nonpathogen - hypothetical protein SCO3689 1 None None None 21223251 Common - hypothetical protein 2SCK803c SCO4877 2 None None None 21225576 Common - hypothetical protein SCO7300 14 None None None 21219952 Common - uracyl permease SCO1450 123 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 21220654 Common - dihydrolipoamide dehydrogenase SCO2180 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 21225709 Common - hypothetical protein SCO7439 17 COG3340 PepE, Peptidase E Amino acid transport and metabolism 21219516 Common - superoxide dismutase SCO0999 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 32141329 Common - hypothetical protein SCO7347 34 COG1309 AcrR, Transcriptional regulator Transcription 21225043 Nonpathogen - hypothetical protein SCO6749 2 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223492 Common - peptidase SCO5122 50 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21223978 Common - hypothetical protein SCO5623 18 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21218636 Common - hypothetical protein SCO0061 19 COG3538 COG3538, Uncharacterized conserved protein Function unknown 21218813 Common - LysR-family transcriptional regulator SCO0262 42 COG0583 LysR, Transcriptional regulator Transcription 21219308 Nonpathogen - integral membrane protein SCO0785 1 None None None 21218926 Common - hypothetical protein SCO0383 150 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21224331 Common - integral membrane cytochrome biogenesis protein SCO5994 45 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 21225755 Common - integral membrane binding protein dependent transport protein SCO7487 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21224048 Common - prolyl-tRNA synthetase SCO5699 246 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21222006 Common - two component sensor kinase SCO3589 202 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21222550 Common - secreted 5'-nucleotidase SCO4152 127 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 21220181 Common - NTP pyrophosphohydrolase SCO1686 27 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 21219686 Common - hypothetical protein SCO1175 41 COG0657 Aes, Esterase/lipase Lipid metabolism 21219907 Nonpathogen - hypothetical protein SCO1403 1 None None None 21225858 Common anmK anhydro-N-acetylmuramic acid kinase SCO7595 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 21221584 Common - secreted protein SCO3146 2 COG1520 COG1520, FOG: WD40-like repeat Function unknown 21223862 Common - regulatory protein SCO5506 126 COG3899 COG3899, Predicted ATPase General function prediction only 21225325 Common - marR-family transcriptional regulator SCO7042 31 COG1846 MarR, Transcriptional regulators Transcription 21219072 Common - secreted protein SCO0537 17 COG3868 COG3868, Uncharacterized conserved protein Function unknown 21222742 Common - DNA invertase SCO4351 134 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 21224450 Common - quinone binding protein SCO6123 27 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 21223312 Common - ECF-sigma factor SCO4938 52 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220794 Common - hypothetical protein SCO2326 13 None None None 21224834 Common - nitrate reductase gamma chain NarI SCO6532 60 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 21219758 Nonpathogen - hypothetical protein 2SCG124c SCO1249 1 None None None 21221677 Nonpathogen - secreted protein SCO3244 2 None None None 21222115 Common - DNA-binding protein SCO3702 27 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 21223080 Nonpathogen - hypothetical protein SCO4700 2 None None None 21225736 Nonpathogen - hypothetical protein SCO7467 3 None None None 21223027 Common - aspartate aminotransferase SCO4645 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 21223334 Common - marR-family transcriptional regulator SCO4961 56 COG1846 MarR, Transcriptional regulators Transcription 32141271 Common - peptide transport system permease SCO5715 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21219614 Common - integral membrane protein SCO1099 23 COG1289 COG1289, Predicted membrane protein Function unknown 21222376 Common - hypothetical protein SCO3972 2 None None None 21222066 Common - hypothetical protein SCO3651 29 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 21225865 Common - tetR-family transcriptional regulator SCO7602 74 COG1309 AcrR, Transcriptional regulator Transcription 21221704 Nonpathogen - dehydrogenase SCO3271 1 None None None 21222076 Nonpathogen - hypothetical protein SCO3662 1 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 21222572 Nonpathogen - hypothetical protein SCO4175 1 None None None 21223529 Common - hypothetical protein SCO5160 6 None None None 21219141 Nonpathogen - regulatory protein SCO0608 1 None None None 21223597 Common - permease SCO5229 42 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 21225100 Nonpathogen - hypothetical protein SCO6807 6 None None None 21225446 Common - sugar-transporter integral membrane protein SCO7166 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21223499 Common - ABC transporter ATP-binding protein SCO5129 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21224980 Common - ABC transporter ATP-binding protein SCO6684 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21219863 Common - hypothetical protein SCO1357 13 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21219888 Common - hypothetical protein SCO1384 66 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 21220615 Nonpathogen - hypothetical protein SCO2138 2 None None None 21221990 Common - hydrolase SCO3572 143 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21220620 Common - two component system response regulator SCO2143 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21225486 Nonpathogen - hypothetical protein SCO7209 1 None None None 21222362 Nonpathogen - integral membrane protein SCO3957 4 None None None 21218755 Common - alcohol dehydrogenase SCO0199 214 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 21219372 Common - PfkB-family carbohydrate kinase SCO0851 69 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21218624 Nonpathogen - hypothetical protein SCO0045 1 None None None 21221344 Common - probable secreted penicillin-binding protein SCO2897 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 21222826 Nonpathogen - integral membrane protein SCO4438 5 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 21225571 Common - LuxR-family regulator SCO7295 87 COG3899 COG3899, Predicted ATPase General function prediction only 21222696 Common - transcriptional regulator SCO4303 86 COG1309 AcrR, Transcriptional regulator Transcription 21224766 Common - cation-transporting ATPase SCO6460 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 21225536 Common - hypothetical protein SCO7259 47 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21220348 Nonpathogen - secreted protein SCO1860 1 None None None 21221597 Common - integral membrane transport protein SCO3160 42 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 21225874 Common - hypothetical protein SCO7612 117 COG2353 COG2353, Uncharacterized conserved protein Function unknown 21219592 Common - sugar kinase SCO1077 154 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 32141311 Common - two-component system response regulator SCO6685 152 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220849 Common - hypothetical protein SCO2382 6 None None None 21221765 Common - araC-family transcriptional regulator SCO3335 125 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21221555 Nonpathogen - hypothetical protein SCO3116 3 None None None 21223552 Common - ATP-dependent DNA helicase SCO5183 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 21225642 Nonpathogen - hypothetical protein SCO7368 2 None None None 21222495 Common - integral membrane protein SCO4093 9 COG1409 Icc, Predicted phosphohydrolases General function prediction only 21224564 Common - malate synthase SCO6243 61 COG2225 AceB, Malate synthase Energy production and conversion 21220868 Common - dehydratase SCO2401 120 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21220971 Common recO DNA repair protein RecO SCO2510 48 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 21220414 Common - ABC transporter, ATP-binding subunit SCO1928 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21223451 Common - hydrolase SCO5080 50 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21220231 Nonpathogen - hypothetical protein SCO1737 3 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 21219177 Common - short chain oxidoreductase SCO0647 230 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21221327 Nonpathogen - hypothetical protein SCO2878 1 None None None 21219418 Common - regulator SCO0898 11 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21222320 Common - hypothetical protein SCO3913 47 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 21224383 Common - hypothetical protein SCO6052 34 COG3211 PhoX, Predicted phosphatase General function prediction only 21222564 Common - tetR-family transcriptional regulator SCO4167 5 COG1309 AcrR, Transcriptional regulator Transcription 21221619 Common - hypothetical protein SCO3183 53 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 21219636 Common - regulatory protein SCO1122 17 COG0583 LysR, Transcriptional regulator Transcription 21221735 Common argS arginyl-tRNA synthetase SCO3304 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21222268 Nonpathogen - DNA-binding protein SCO3859 2 COG2522 COG2522, Predicted transcriptional regulator General function prediction only 21223441 Common - oxidoreductase SCO5069 173 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21220888 Nonpathogen - secreted protein SCO2423 1 None None None 21225082 Common - fatty oxidation protein SCO6789 159 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21226003 Common - insertion element transposase SCO7746 69 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21223053 Nonpathogen - secreted protein SCO4672 1 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21225568 Common - threonine dehydratase SCO7292 198 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 21219238 Common - transcriptional activator SCO0712 19 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223989 Nonpathogen - integral membrane protein SCO5638 3 None None None 21224493 Nonpathogen - hypothetical protein SCO6168 1 None None None 21225267 Common - ABC transporter ATP-binding protein SCO6981 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 21220029 Nonpathogen - hypothetical protein SCO1529 1 None None None 21218685 Common - oxidoreductase SCO0125 21 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 21220041 Common - regulator SCO1541 8 None None None 21225563 Common - oxidoreducatse SCO7286 184 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21221787 Common - two-component system response regulator SCO3358 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21223561 Common - hypothetical protein SCO5192 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 21225377 Common - hydrolase SCO7095 77 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221488 Common - secreted protein SCO3045 57 COG1316 LytR, Transcriptional regulator Transcription 21221745 Common - dehydrogenase SCO3314 100 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21222073 Common - aminotransferase SCO3658 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 21221102 Common - integral membrane protein SCO2645 57 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21220103 Common - hypothetical protein SCO1606 8 COG2367 PenP, Beta-lactamase class A Defense mechanisms 21220232 Common - hypothetical protein SCO1738 152 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 21225287 Common - integral membrane protein SCO7001 208 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 21224710 Nonpathogen - hypothetical protein SCO6402 1 None None None 21218830 Common - hypothetical protein SCO0280 37 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 21223158 Common - serine/threonine protein kinase SCO4779 146 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21222493 Common - DNA-binding protein SCO4091 12 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 21223660 Nonpathogen - hypothetical protein SCO5295 1 None None None 21224401 Common - A-factor receptor homolog SCO6071 117 COG1309 AcrR, Transcriptional regulator Transcription 21222536 Common - phosphate transport protein SCO4138 167 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 21223230 Nonpathogen - integral membrane protein SCO4854 3 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 21225071 Common - transcriptional regulator SCO6778 84 COG1309 AcrR, Transcriptional regulator Transcription 21218698 Common - hypothetical protein SCO0139 14 None None None 21218661 Nonpathogen - hypothetical protein SCO0095 2 None None None 21219697 Common - lacI-family transcriptional regulator SCO1186 126 COG1609 PurR, Transcriptional regulators Transcription 21225474 Nonpathogen - hypothetical protein SCO7195 1 None None None 21218614 Nonpathogen - hypothetical protein SCO0035 1 None None None 21222522 Common - two-component system response regulator SCO4123 199 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21224017 Common - ABC-transporter polyamine-binding lipoprotein SCO5667 118 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 21220705 Nonpathogen - integral membrane protein SCO2233 6 None None None 21223783 Common - pyruvate kinase SCO5423 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 21225073 Common - secreted protein SCO6780 7 None None None 32141154 Common - secreted alkaline phosphatase SCO2068 57 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 21221685 Common - replication initiator protein SCO3252 5 None None None 21223436 Common - bifunctional protein SCO5064 116 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 21224926 Common - hypothetical protein SCO6629 6 None None None 21223734 Common - ATP synthase epsilon chain SCO5374 169 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 21220457 Common - hypothetical protein SCO1973 92 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21224754 Common - AraC-like transcriptional regulator SCO6448 113 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21225720 Nonpathogen - hypothetical protein SCO7451 3 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 21224334 Common - secreted protein SCO5997 12 COG3953 COG3953, SLT domain proteins General function prediction only 21219726 Nonpathogen - integral membrane protein SCO1216 1 None None None 32141253 Common - oxidoreductase SCO5075 183 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21222688 Common - cold shock protein SCO4295 184 COG1278 CspC, Cold shock proteins Transcription 21220114 Common - integral membrane protein SCO1617 20 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 21223969 Common - transcriptional regulator SCO5614 4 COG1476 COG1476, Predicted transcriptional regulators Transcription 21221620 Common - potassium/proton antiporter SCO3185 109 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 21222134 Common - carbonic anhydrase SCO3721 105 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 21219607 Common - hypothetical protein SCO1092 15 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21224933 Common - bacteriophage (phiC31) resistance gene pglZ SCO6636 9 None None None 21223935 Common - transmembrane protein SCO5579 49 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 21220581 Common - carotenoid dehydrogenase (secreted protein) SCO2101 68 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21222238 Common - molybdopterin-guanine dinucleotide biosynthesis protein SCO3828 10 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 21224392 Common - ABC transporter ATP-binding protein SCO6062 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 21225774 Common - dioxygenase SCO7507 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 21221518 Common - cystathionine beta-synthase SCO3077 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 21221451 Common - two-component system response regulator SCO3008 222 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 31340547 Common - secreted protein SCO1793 20 COG4326 Spo0M, Sporulation control protein General function prediction only 21223713 Common - arginyl tRNA synthetase SCO5352 49 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21225811 Common - lipoprotein SCO7546 98 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 21225302 Common - hypothetical protein SCO7017 21 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 21221664 Common - CDA peptide synthetase I SCO3230 220 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21220517 Common trpA tryptophan synthase subunit alpha SCO2036 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 21223641 Nonpathogen - hypothetical protein 2SC7G1136 SCO5274 3 None None None 21221874 Common - hypothetical protein SCO3449 2 None None None 21224881 Common - transmembrane transport protein SCO6581 104 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21224237 Common - methyltransferase SCO5895 42 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 21220141 Common - hypothetical protein SCO1645 3 None None None 21223766 Common - hypothetical protein SCO5406 18 COG2013 COG2013, Uncharacterized conserved protein Function unknown 21223342 Common - regulatory protein SCO4969 10 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 21224897 Common - beta-glucosidase SCO6597 120 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 21223403 Common - integral membrane protein SCO5030 35 COG0628 PerM, Predicted permease General function prediction only 21225415 Nonpathogen - hypothetical protein SCO7133 1 None None None 21219295 Common - regulatory protein SCO0772 57 COG1309 AcrR, Transcriptional regulator Transcription 21222225 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 SCO3815 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 21225832 Common - regulatory protein SCO7568 126 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21222861 Common - integral membrane protein SCO4474 24 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 21224641 Common - integral membrane protein SCO6327 8 None None None 21220229 Common - secreted lipase SCO1735 39 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 21224029 Common - cytidine deaminase SCO5680 12 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 21221035 Common - phosphoglycerate mutase SCO2576 60 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21221177 Common - ABC transporter ATP-binding protein SCO2723 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21223810 Common - ABC transporter, ATP-binding subunit SCO5452 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21221771 Nonpathogen - integral membrane protein SCO3341 1 None None None 21220293 Common - oxidoreductase SCO1803 102 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21224038 Common - beta-galactosidase SCO5689 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 21223571 Common - secreted protein SCO5202 49 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 21222474 Common - luxR family two component system response regulator SCO4072 199 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220895 Common - alpha-L-arabinofuranosidase SCO2431 31 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 21224226 Nonpathogen - hypothetical protein SCO5884 2 None None None 21225681 Common - LacI-family transcriptional regulator SCO7411 126 COG1609 PurR, Transcriptional regulators Transcription 21222226 Common - branched-chain alpha keto acid dehydrogenase E1 beta subunit SCO3816 220 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 21225093 Common - 2-amino-3-ketobutyrate coenzyme A ligase SCO6800 214 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 21221441 Common - transferase SCO2997 25 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 21225124 Common - methylmalonyll-CoA mutase SCO6832 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 21219379 Nonpathogen - hypothetical protein SCO0858 1 None None None 21222559 Common - molybdopterin converting factor SCO4161 5 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 21222820 Nonpathogen - hypothetical protein SCO4432 1 None None None 21220758 Nonpathogen - membrane protein SCO2289 2 COG2259 COG2259, Predicted membrane protein Function unknown 21223829 Common gcvT glycine cleavage system aminomethyltransferase T SCO5472 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 21224959 Common - transketolase SCO6663 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 21220577 Common - hypothetical protein SCO2097 16 None None None 21224035 Common - lipoprotein SCO5686 9 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21224082 Common - integral membrane protein SCO5735 7 None None None 21222263 Common - putative septation inhibitor protein SCO3854 10 None None None 21220596 Common - D-lactate dehydrogenase SCO2118 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 21219949 Common - ROK-family transcriptional regulatory protein SCO1447 154 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21224966 Common - glucosidase SCO6670 52 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 21220998 Common era GTP-binding protein Era SCO2539 217 COG1159 Era, GTPase General function prediction only 21223468 Common - short-chain oxidoreductase SCO5097 230 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 32141178 Common - hypothetical protein SCO2680 6 None None None 21222447 Nonpathogen - hypothetical protein 2SCD6010 SCO4044 1 None None None 21224477 Common - methylated-DNA-protein-cysteine methyltransferase SCO6151 216 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 21223627 Common - secreted protein SCO5260 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 21219065 Common - transcriptional regulator SCO0530 125 COG2188 PhnF, Transcriptional regulators Transcription 32141308 Common - beta-glucosidase SCO6604 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 21224590 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta SCO6269 133 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 21219961 Common - amino acid transporter SCO1459 182 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 21222469 Common - DNA polymerase III subunits gamma and tau SCO4067 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 21224091 Common - hypothetical protein SCO5745 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 32141305 Nonpathogen - hypothetical protein SCO6516 2 None None None 21224748 Common - alcohol dehydrogenase SCO6442 122 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 21222187 Nonpathogen - hypothetical protein SCO3776 1 None None None 21220836 Common - hypothetical protein SCO2368 29 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21222512 Common - hypothetical protein SCO4112 3 None None None 21223415 Common fumC fumarate hydratase SCO5042 234 COG0114 FumC, Fumarase Energy production and conversion 21221511 Common - chlorohydrolase SCO3070 104 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 21224377 Common - hypothetical protein SCO6046 7 COG1990 COG1990, Uncharacterized conserved protein Function unknown 21222841 Common - hypothetical protein SCO4453 36 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 21222286 Common - DNA polymerase III subunit beta SCO3878 212 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 21222650 Nonpathogen - hypothetical protein SCO4255 1 None None None 21223678 Common - polyketide cyclase SCO5315 4 COG3427 COG3427, Uncharacterized conserved protein Function unknown 21225844 Common - hypothetical protein SCO7580 12 None None None 21222965 Common - hypothetical protein SCO4582 13 COG3953 COG3953, SLT domain proteins General function prediction only 21224597 Common - integral membrane transport protein SCO6278 77 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21218605 Nonpathogen - secreted protein SCO0026 1 None None None 21220220 Common - ATPase SCO1726 30 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 21219354 Nonpathogen - hypothetical protein SCO0833 2 None None None 21224329 Nonpathogen - integral membrane protein SCO5992 3 None None None 21221522 Nonpathogen - hypothetical protein SCO3081 1 None None None 21219982 Common - orotidine 5'-phosphate decarboxylase SCO1481 64 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 21223367 Nonpathogen - hypothetical protein 2SCK3617 SCO4994 1 None None None 21219368 Nonpathogen - lyase SCO0847 4 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21219703 Common - hypothetical protein SCO1192 41 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 21222308 Common - secreted penicillin-binding protein SCO3901 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 21223295 Common - acyl-CoA carboxylase complex A subunit SCO4921 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 32141322 Common - regulatory protein SCO7137 40 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 21224848 Common - secreted cellulase SCO6546 22 None None None 21219214 Common - hypothetical protein SCO0685 9 None None None 21218965 Common - membrane transport protein SCO0423 53 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 32141184 Common - transmembrane transport protein SCO2937 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21218871 Common - secreted protein SCO0324 47 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 21218746 Common - methyltransferase SCO0190 50 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21223322 Common - nitrate reductase delta chain NarJ3 SCO4949 26 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 21219164 Common - RNA polymerase sigma factor SigK SCO0632 127 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220801 Nonpathogen - hypothetical protein SCO2333 1 None None None 21225282 Common - RNA polymerase sigma factor SCO6996 18 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21223511 Common - secreted protein SCO5142 5 None None None 21222261 Common - hypothetical protein SCO3852 8 None None None 21225925 Common - hypothetical protein SCO7664 44 COG5483 COG5483, Uncharacterized conserved protein Function unknown 21219913 Common - GntR-family transcriptional regulator SCO1410 109 COG1802 GntR, Transcriptional regulators Transcription 21225038 Nonpathogen - hypothetical protein SCO6744 1 None None None 21218647 Nonpathogen - hypothetical protein SCO0073 1 None None None 21224252 Common - probable secreted protease SCO5913 10 None None None 21222719 Nonpathogen - hypothetical protein SCO4327 12 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 21225226 Common - hypothetical protein SCO6939 21 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 21222812 Nonpathogen - secreted protein SCO4424 1 None None None 21224076 Nonpathogen - hypothetical protein SCO5729 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 21218981 Common - hypothetical protein SCO0439 28 COG3817 COG3817, Predicted membrane protein Function unknown 21221217 Nonpathogen - hypothetical protein SCO2765 1 None None None 21225367 Nonpathogen - hypothetical protein SCO7085 1 None None None 21219842 Common - lipoprotein N-acyltransferase (integral membrane) SCO1336 159 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 21223971 Nonpathogen - hypothetical protein SCO5616 1 None None None 21225785 Common - sugar acetyltransferase SCO7519 149 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 21218864 Common - DNA-binding protein SCO0316 17 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21220665 Nonpathogen - oxidoreductase SCO2191 18 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21225674 Nonpathogen - hypothetical protein SCO7403 1 None None None 21218709 Nonpathogen - integral membrane protein SCO0151 1 None None None 21218765 Common - hypothetical protein SCO0211 23 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21222160 Common - cold shock protein SCO3748 181 COG1278 CspC, Cold shock proteins Transcription 21224489 Common - sensor kinase SCO6163 128 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21225605 Nonpathogen - membrane protein SCO7330 1 None None None 21225337 Common - hypothetical protein SCO7054 33 COG1695 COG1695, Predicted transcriptional regulators Transcription 21222405 Nonpathogen - secreted protein SCO4002 1 None None None 21223748 Common - hypothetical protein SCO5388 37 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 21221209 Common - LysR-family transcriptional regulator SCO2757 71 COG0583 LysR, Transcriptional regulator Transcription 21221740 Nonpathogen - hypothetical protein SCO3309 1 None None None 21223620 Nonpathogen - hypothetical protein 2SC7G1115 SCO5253 1 None None None 21218679 Common - xylosidase/arabinosidase SCO0118 43 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 21225665 Common - integral membrane protein SCO7394 3 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21224136 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase SCO5791 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 21222079 Nonpathogen - regulatory protein SCO3665 7 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21222489 Common - phosphoribosylaminoimidazole synthetase SCO4087 224 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 21222148 Common - RNA polymerase ECF sigma factor SCO3736 23 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21222946 Common - NADH dehydrogenase subunit B SCO4563 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 21220842 Common - secreted protein SCO2375 9 None None None 21222703 Common - hypothetical protein SCO4310 10 None None None 21222749 Common - tetR family transcriptional regulatory protein SCO4358 26 COG1309 AcrR, Transcriptional regulator Transcription 21219227 Common - probable ABC transporter protein, ATP-binding component SCO0700 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 21221528 Nonpathogen - hypothetical protein SCO3088 1 None None None 21221004 Common - transmembrane efflux protein SCO2545 3 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 32141143 Common hisG ATP phosphoribosyltransferase SCO1438 213 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 21220495 Common - two-component system response regulator SCO2013 195 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 21223741 Common - hypothetical protein SCO5381 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 21221596 Common - hypothetical protein SCO3159 55 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 21220138 Common - LacI family regulator SCO1642 124 COG1609 PurR, Transcriptional regulators Transcription 21224270 Common - arabinofuranosidase SCO5932 16 None None None 21224546 Nonpathogen - secreted protein SCO6224 2 None None None 21225866 Nonpathogen - hypothetical protein SCO7604 6 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 21219848 Common - hypothetical protein SCO1342 5 None None None 21221972 Nonpathogen - small membrane protein SCO3553 2 None None None 21221198 Common - ABC transporter protein, ATP binding component SCO2746 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 21218649 Nonpathogen - hypothetical protein SCO0075 1 None None None 21223163 Common - hypothetical protein SCO4784 9 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 21222856 Common - glutamate-1-semialdehyde aminotransferase SCO4469 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 21219572 Common - sugar transport integral membrane protein SCO1057 192 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21218598 Nonpathogen - hypothetical protein SCO0016 1 None None None 21219578 Common - sugar transport integral membrane protein SCO1063 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21223543 Common - transferase SCO5174 99 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21225628 Common - hypothetical protein SCO7354 40 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225553 Nonpathogen - hypothetical protein SCO7276 2 None None None 21221045 Nonpathogen - hypothetical protein SCO2586 3 None None None 21225678 Common - probable solute-binding lipoprotein SCO7408 75 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21226018 Nonpathogen - hypothetical protein SCO7764 1 None None None 21220990 Nonpathogen - hypothetical protein SCO2530 1 None None None 21226056 Nonpathogen - DNA-binding protein SCO7806 5 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 21224487 Nonpathogen - secreted protein SCO6161 1 None None None 21219563 Common - integral membrane protein SCO1047 9 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21220808 Common - hypothetical protein SCO2340 8 None None None 21225660 Common - hypothetical protein SCO7387 6 None None None 21222519 Common - hypothetical protein SCO4120 96 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21224094 Common - sensory histidine kinase SCO5748 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21219393 Common - hypothetical protein SCO0872 155 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21219528 Common - hypothetical protein SCO1011 26 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 21223410 Common - hypothetical protein SCO5037 8 COG4877 COG4877, Uncharacterized protein conserved in bacteria Function unknown 21222927 Common - hypothetical protein SCO4543 6 None None None 21224845 Nonpathogen - hypothetical protein SCO6543 1 None None None 21221966 Common hppA membrane-bound proton-translocating pyrophosphatase SCO3547 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 21226025 Nonpathogen - hypothetical protein SCO7772 1 None None None 21220486 Common - formate dehydrogenase SCO2004 177 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 21225014 Common - ABC transporter SCO6720 239 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21220307 Common - tyrosyl-tRNA synthetase SCO1818 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21226076 Common - transposase SCO7827 36 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 21221629 Common - lipoprotein SCO3194 25 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 21224293 Common - hypothetical protein SCO5955 6 None None None 21224417 Common - solute-binding transport protein SCO6088 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21221832 Common - hypoxanthine phosphoribosyltransferase SCO3405 157 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 21223891 Nonpathogen - hypothetical protein SCO5536 1 None None None 21221430 Common - hypothetical protein SCO2986 101 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 21222332 Common - regulator SCO3926 8 None None None 21220533 Common - imidazoleglycerol-phosphate dehydratase SCO2052 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 21225425 Common - transcriptional regulator SCO7145 22 COG1846 MarR, Transcriptional regulators Transcription 21225004 Common - glycosyl hydrolase SCO6710 38 None None None 21221414 Common - cell division ATP-binding protein SCO2969 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 21224287 Common - hypothetical protein SCO5949 9 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 32141217 Common - E1-alpha branched-chain alpha keto acid dehydrogenase SCO3831 157 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 32141278 Common - xylanase A SCO5931 46 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 21223258 Common - lipoprotein SCO4884 105 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 21224234 Common - polyketide synthase SCO5892 235 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21219305 Common - ribose-phosphate pyrophosphokinase SCO0782 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 21221567 Common - TetR-family transcriptional regulator SCO3129 133 COG1309 AcrR, Transcriptional regulator Transcription 21223224 Common - integral membrane protein SCO4848 6 None None None 21223919 Common - phosphomethylpyrimidine kinase SCO5563 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 21225353 Common - hypothetical protein SCO7070 2 None None None 21225743 Common - phenylacetic acid degradation NADH oxidoreductase PaaE SCO7475 148 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 21224189 Common - thymidine kinase SCO5845 67 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 21223876 Nonpathogen - hypothetical protein SCO5521 1 None None None 21222587 Common - hydrolase SCO4191 60 COG0546 Gph, Predicted phosphatases General function prediction only 21221037 Nonpathogen - membrane protein SCO2578 3 COG1316 LytR, Transcriptional regulator Transcription 21222504 Common - peptidase SCO4103 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 21219815 Common - 4-hydroxybenzoate 3-monooxygenase SCO1308 54 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21224974 Common - iron-sulfur oxidoreductase beta subunit SCO6678 102 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 21225197 Common - DNA ligase SCO6907 24 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 21225250 Nonpathogen - lipoprotein SCO6963 1 None None None 21224518 Common - response regulator SCO6194 8 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21219338 Common - hypothetical protein SCO0817 34 COG1556 COG1556, Uncharacterized conserved protein Function unknown 21223118 Nonpathogen - lipoprotein SCO4739 1 None None None 21224039 Common - hypothetical protein SCO5690 17 None None None 21220932 Common - reductase SCO2469 235 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 21221562 Common - 50S ribosomal protein L25/general stress protein Ctc SCO3124 168 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 32141215 Common - ABC transporter integral membrane subunit SCO3754 12 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 21222789 Common - hypothetical protein SCO4399 7 None None None 21224555 Common - transcriptional regulator SCO6233 124 COG1609 PurR, Transcriptional regulators Transcription 21224575 Common - two-component system response regulator SCO6254 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220028 Common - elongation factor G SCO1528 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 21221535 Common eno phosphopyruvate hydratase SCO3096 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 21224323 Common - oxidoreductase SCO5986 11 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21220963 Common - transport protein SCO2502 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225202 Nonpathogen - hypothetical protein SCO6914 1 None None None 21221256 Common - hypothetical protein SCO2805 5 None None None 21221312 Nonpathogen - hypothetical protein SCO2862 1 None None None 21224808 Common - gas vesicle synthesis protein SCO6505 22 None None None 21224370 Common - integral membrane protein SCO6038 125 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 21218975 Nonpathogen - transcriptional regulator SCO0433 14 COG1378 COG1378, Predicted transcriptional regulators Transcription 21223953 Common - signal peptidase I SCO5598 182 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 21220217 Common - RNA polymerase sigma factor SigK SCO1723 89 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21221618 Common - UTP-glucose-1-phosphate uridylyltransferase SCO3182 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 21223040 Common rpsL 30S ribosomal protein S12 SCO4659 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 21219955 Common - hypothetical protein SCO1453 13 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21220462 Common - DNA-binding protein SCO1979 6 None None None 21224677 Common - two-component regulator SCO6364 203 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21225301 Common - LacI-family transcriptional regulatory protein SCO7016 123 COG1609 PurR, Transcriptional regulators Transcription 21218953 Nonpathogen - hypothetical protein SCO0411 1 None None None 21225431 Common - hypothetical protein SCO7151 22 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223881 Common ureC urease subunit alpha SCO5526 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 21220034 Common - DNA polymerase III subunit epsilon SCO1534 12 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 32141316 Nonpathogen - regulator (fragment) SCO6895 1 None None None 21224675 Common - two-component sensor SCO6362 64 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21225003 Common - hypothetical protein SCO6709 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 21218669 Common - endo-1,4-beta-xylanase (secreted protein) SCO0105 8 None None None 21221047 Common - integral membrane protein SCO2588 3 None None None 21223574 Common - hydrogen peroxide sensitive repressor SCO5206 116 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 21219765 Common - ABC transport system integral membrane protein SCO1257 7 None None None 21223277 Common - hypothetical protein SCO4903 15 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 21224422 Common - secreted protein SCO6093 39 COG2138 COG2138, Uncharacterized conserved protein Function unknown 21221277 Common - hypothetical protein SCO2827 5 None None None 21222157 Common - lipoprotein SCO3745 4 None None None 31340544 Common - TetR-family transcriptional regulator SCO1712 56 COG1309 AcrR, Transcriptional regulator Transcription 21224822 Common - RNA polymerase sigma factor SCO6520 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 21225114 Common - hypothetical protein SCO6821 245 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 21219400 Nonpathogen - membrane protein SCO0880 1 None None None 21221328 Common - hypothetical protein SCO2879 7 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21219414 Common - membrane protein SCO0894 47 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21225624 Common - membrane efflux protein SCO7350 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21218763 Nonpathogen - hypothetical protein SCO0209 1 None None None 21222278 Nonpathogen - integral membrane protein SCO3870 1 None None None 21222757 Common - phosphoserine aminotransferase SCO4366 176 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 21222880 Common - DNA polymerase related protein SCO4495 149 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 21222743 Common - oxidoreductase SCO4352 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21225088 Common - hypothetical protein SCO6795 10 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21219971 Common - hypothetical protein SCO1469 4 None None None 21222243 Common - 3-hydroxybutyryl-CoA dehydrogenase SCO3834 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21225685 Common - racemase SCO7415 110 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21225787 Common - secreted peptidase SCO7521 127 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21224015 Nonpathogen - integral membrane protein SCO5664 1 None None None 21222395 Nonpathogen - hypothetical protein SCO3992 1 None None None 21221497 Common - hypothetical protein SCO3055 14 None None None 21219773 Common - lipase SCO1265 27 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 21224264 Nonpathogen - hypothetical protein SCO5925 4 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 21224947 Nonpathogen - hypothetical protein SCO6650 21 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 21221184 Common - probable cation-transporting P-type ATPase SCO2731 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 21219272 Common - hydrolase SCO0748 117 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 21221724 Common - hypothetical protein SCO3292 6 None None None 21224451 Nonpathogen - hypothetical protein SCO6124 1 None None None 21220943 Common - secreted protein SCO2480 12 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 21225703 Common - small neutral protease regulatory protein SCO7433 148 COG0583 LysR, Transcriptional regulator Transcription 21220434 Nonpathogen - hypothetical protein SCO1949 1 None None None 21219188 Common - gas vesicle synthesis protein SCO0658 8 None None None 21223331 Common - cystathionine gamma-synthase SCO4958 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 21225248 Common - hypothetical protein SCO6961 7 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 21223491 Common - peptide transport system ATP-binding protein SCO5121 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 21220989 Common - metalloprotease SCO2529 45 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 21222871 Common - transcriptional regulator SCO4485 50 COG2378 COG2378, Predicted transcriptional regulator Transcription 21225884 Common - NAD(P) transhydrogenase beta subunit SCO7622 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 21224154 Common - hydrolase SCO5809 19 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21221546 Common - lipoprotein SCO3107 24 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 21222541 Common - mutT-like protein SCO4143 24 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 21225026 Common - fatty acid oxidative multifunctional enzyme SCO6732 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21219992 Common - elongation factor P SCO1491 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 21223742 Nonpathogen - ABC transporter, integral membrane subunit SCO5382 4 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21224986 Common - integral membrane protein SCO6692 10 None None None 21222215 Common - hypothetical protein SCO3805 7 COG4894 COG4894, Uncharacterized conserved protein Function unknown 21221839 Common - hypothetical protein SCO3412 90 COG0393 COG0393, Uncharacterized conserved protein Function unknown 21220347 Common - hypothetical protein SCO1859 203 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 21223721 Common - methylase SCO5361 220 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 21219441 Common - succinate dehydrogenase/fumarate reductase iron-sulfur subunit SCO0922 204 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 21225101 Common - ArsR-family transcriptional regulator SCO6808 152 COG0640 ArsR, Predicted transcriptional regulators Transcription 21219005 Common - non-heme chloroperoxidase (chloride peroxidase) SCO0465 159 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225621 Common - membrane transport protein SCO7346 173 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225894 Common - secreted endo-beta-N-acetylglucosaminidase SCO7633 7 None None None 21222318 Common - replicative DNA helicase SCO3911 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 21223668 Nonpathogen - lipoprotein SCO5305 1 None None None 21223528 Common - integral membrane transport protein SCO5159 67 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 32141283 Common - protoporphyrinogen oxidase SCO6041 47 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 21218710 Common - secreted protein SCO0153 16 None None None 21222443 Nonpathogen - hypothetical protein S2SCD6006 SCO4040 1 None None None 21223171 Common - NPL/P60 family secreted protein SCO4793 155 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21224993 Common - protocatechuate 3,4-dioxygenase alpha subunit SCO6699 38 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 21219478 Common - hydrolase (secreted protein) SCO0960 78 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21220170 Nonpathogen - secreted protein SCO1674 1 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 21221843 Common - glutamate decarboxylase SCO3416 66 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 21224135 Nonpathogen - hypothetical protein SCO5790 1 None None None 21222471 Nonpathogen - integral membrane protein SCO4069 1 None None None 21219586 Common - two component system sensor kinase SCO1071 88 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 32141237 Common - lipoprotein SCO4458 39 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 21223843 Common - pyridoxal-phosphate-dependent aminotransferase SCO5486 234 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 21221195 Common - hypothetical protein SCO2743 72 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21222852 Common - hypothetical protein SCO4465 19 COG1695 COG1695, Predicted transcriptional regulators Transcription 21222887 Common - acetyl-CoA acetyltransferase SCO4502 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21218683 Common - hypothetical protein SCO0123 6 None None None 21223687 Common - oxidoreductase SCO5324 21 COG0778 NfnB, Nitroreductase Energy production and conversion 21219222 Nonpathogen - hypothetical protein SCO0694 1 None None None 21221802 Common - Clp-family ATP-binding protease SCO3373 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 21223477 Common - fumarate reductase iron-sulfur subunit SCO5106 204 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 21222563 Nonpathogen - integral membrane protein SCO4166 3 None None None 21219835 Nonpathogen - hypothetical protein SCO1329 1 None None None 21220424 Common - hypothetical protein SCO1938 19 COG3429 COG3429, Glucose-6-P dehydrogenase subunit Carbohydrate transport and metabolism 21221386 Common - oxidoreductase SCO2940 112 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 21219951 Common - hypothetical protein SCO1449 5 COG0824 FcbC, Predicted thioesterase General function prediction only 21224942 Common - transport system permease protein SCO6645 79 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21225916 Common - oxidoreductase SCO7655 187 COG4989 COG4989, Predicted oxidoreductase General function prediction only 21219432 Common - hypothetical protein SCO0912 37 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 21222848 Common - tetR-family transcriptional regulatory protein SCO4461 27 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 21219931 Common - acyl-CoA dehydrogenase SCO1428 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21221631 Common - fructose-specific permease SCO3196 128 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 21225806 Common - hypothetical protein SCO7541 105 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21224612 Common - hypothetical protein SCO6293 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 21221719 Nonpathogen - serine/arginine rich protein SCO3287 1 None None None 21225922 Common - secreted protein SCO7661 50 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 21226089 Nonpathogen - hypothetical protein SCO7840 1 None None None 21224614 Common - ABC transporter ATP-binding protein SCO6295 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21225547 Common - transcriptional regulator SCO7270 190 COG0583 LysR, Transcriptional regulator Transcription 21222859 Common - secreted protein SCO4472 162 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 21223211 Common - hypothetical protein SCO4835 81 COG2128 COG2128, Uncharacterized conserved protein Function unknown 21222776 Nonpathogen - hypothetical protein SCO4386 1 None None None 21223661 Common - tetR-family transcriptional regulator SCO5296 36 COG1309 AcrR, Transcriptional regulator Transcription 21226021 Common - DNA-binding protein SCO7767 41 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 21224550 Common - hypothetical protein SCO6228 3 None None None 21219852 Common - 3-oxoacyl-(ACP) reductase SCO1346 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21224853 Common - oxidoreductase SCO6551 188 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 21221569 Common - hypothetical protein SCO3131 20 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21221747 Common - dehydrogenase SCO3316 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221433 Common - integral membrane protein SCO2989 4 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 21224928 Common - hypothetical protein SCO6631 4 None None None 21220885 Common - secreted protein SCO2419 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 21222271 Nonpathogen - hypothetical protein SCO3862 1 None None None 21224069 Common - serine protease (secreted protein) SCO5722 140 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21226028 Common - secreted protein SCO7775 19 None None None 21222036 Nonpathogen - membrane protei SCO3620 1 None None None 21224636 Common - transport integral membrane protein SCO6320 162 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 21221286 Common - glycosyl transferase SCO2836 91 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21223968 Nonpathogen - hypothetical protein SCO5613 1 None None None 21221359 Nonpathogen - hypothetical protein SCO2912 1 None None None 21224289 Common - transcriptional regulator SCO5951 27 COG1309 AcrR, Transcriptional regulator Transcription 21219089 Common - membrane-bound oxidoreductase SCO0555 97 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 32141246 Common - integral membrane protein SCO4790 19 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 21222449 Nonpathogen - hypothetical protein 2SCD6012c SCO4046 1 None None None 21225146 Nonpathogen - hypothetical protein SCO6855 1 None None None 21223405 Common - alkyl hydroperoxide reductase SCO5032 212 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 32141296 Common - TetR-family transcriptional regulator SCO6299 11 COG1309 AcrR, Transcriptional regulator Transcription 21222606 Nonpathogen - hypothetical protein SCO4210 1 None None None 21220760 Common - secreted acetylxylan esterase SCO2291 98 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21220423 Common - glucose-6-phosphate 1-dehydrogenase SCO1937 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 21220915 Common - rod shape-determining protein SCO2451 172 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 21225308 Nonpathogen - hypothetical protein SCO7023 1 None None None 21218962 Common - homoserine dehydrogenase SCO0420 194 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 21218639 Common - hypothetical protein SCO0064 37 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 32141155 Common - transcriptional regulatory protein SCO2105 15 None None None 21224318 Common - hypothetical protein SCO5981 22 None None None 21224857 Common - LysR-family transcriptional regulator SCO6555 180 COG0583 LysR, Transcriptional regulator Transcription 21223923 Common - DNA methylase SCO5567 213 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 21220331 Nonpathogen - hypothetical protein SCO1842 1 None None None 21218720 Common - hypothetical protein SCO0163 57 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 21223856 Nonpathogen - hypothetical protein SCO5500 1 None None None 21221506 Common - hypothetical protein SCO3065 14 None None None 21225209 Nonpathogen - membrane protein SCO6921 1 None None None 21224452 Nonpathogen - membrane lipoprotein SCO6125 1 None None None 21223206 Common - oxidoreductase SCO4829 93 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 21222419 Common - hypothetical protein SCO4016 22 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 21219545 Nonpathogen - hypothetical protein SCO1029 1 None None None 21220663 Common - acetyltransferase SCO2189 4 COG0456 RimI, Acetyltransferases General function prediction only 21219073 Common - probable sugar transporter sugar binding lipoprotein SCO0538 99 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219348 Common - hypothetical protein SCO0827 3 None None None 21223710 Nonpathogen - integrase SCO5349 5 None None None 21223798 Common - hypothetical protein SCO5439 34 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 21218727 Common - hypothetical protein SCO0170 29 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 32141099 Common - integral membrane protein SCO0120 5 None None None 21219999 Common - shikimate 5-dehydrogenase SCO1498 115 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 21223189 Nonpathogen - integral membrane protein SCO4811 1 None None None 21221352 Common - hypothetical protein SCO2905 50 COG1264 PtsG, Phosphotransferase system IIB components Carbohydrate transport and metabolism 21218886 Common - large secreted protein SCO0341 18 None None None 21220545 Common dnaE DNA polymerase III subunit alpha SCO2064 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 21225796 Common - integral membrane protein SCO7531 56 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 21220767 Common - KHG/KDPG aldolase SCO2298 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 21225313 Common - sugar-binding lipoprotein SCO7028 97 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219129 Common - DNA-binding protein SCO0596 111 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 21222239 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 SCO3829 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 32141112 Nonpathogen - hypothetical protein SCO0480 2 None None None 21222610 Common - AbaA-like regulatory protein SCO4214 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21224170 Nonpathogen - hypothetical protein SCO5826 3 COG3162 COG3162, Predicted membrane protein Function unknown 21223341 Nonpathogen - hypothetical protein SCO4968 2 None None None 21222775 Common - tetR-family transcriptional regulator SCO4385 53 COG1309 AcrR, Transcriptional regulator Transcription 21220228 Common - secreted cellulose-binding protein SCO1734 28 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 21218970 Common - tetR family transcriptional regulator SCO0428 13 COG1309 AcrR, Transcriptional regulator Transcription 21221992 Common - epoxide hydrolase SCO3574 89 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21223336 Common - ABC transporter ATP-binding protein SCO4963 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21225405 Common - acyltransferase SCO7123 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 21225976 Nonpathogen - secreted protein SCO7717 1 None None None 21222412 Common - bifunctional protein (histidine kinase and regulator) SCO4009 82 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21219581 Common - lacI-family transcriptional regulator SCO1066 129 COG1609 PurR, Transcriptional regulators Transcription 21219706 Nonpathogen - hypothetical protein SCO1195 1 None None None 32141290 Common - transferase SCO6180 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 21219673 Common - hypothetical protein SCO1160 17 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21219123 Common - oxidoreductase SCO0590 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 21219351 Common - penicillin-binding protein SCO0830 64 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21220770 Common - hypothetical protein SCO2301 128 COG0327 COG0327, Uncharacterized conserved protein Function unknown 21222590 Common - TetR-family transcriptional regulator SCO4194 13 COG1309 AcrR, Transcriptional regulator Transcription 21225959 Common - nucleotide-binding protein SCO7699 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 21221118 Common - kinase SCO2662 14 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 21223390 Common - araC family regulatory protein SCO5017 47 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21224876 Common - hypothetical protein SCO6575 21 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21225044 Common - isopentenyl-diphosphate delta-isomerase SCO6750 55 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 21221951 Common - hypothetical protein SCO3530 6 None None None 21223933 Common - chromosome associated protein SCO5577 178 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 21224783 Common - secreted peptidase SCO6479 24 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21220984 Nonpathogen - hypothetical protein SCO2523 3 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 21222174 Common - hypothetical protein SCO3763 26 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21225557 Common - ATP-dependent Clp protease proteolytic subunit 2 SCO7280 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21219948 Nonpathogen - integral membrane protein SCO1446 1 None None None 21221501 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit PurE SCO3059 230 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 21223643 Nonpathogen - hypothetical protein SCO5276 2 None None None 21223035 Common rplL 50S ribosomal protein L7/L12 SCO4653 213 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 21220510 Nonpathogen - secreted protein SCO2029 1 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 21225462 Common - branched amino acid transport system permease SCO7183 122 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 21221512 Common - N-formimino-L-glutamate deiminase SCO3071 139 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 21223135 Common - hypothetical protein SCO4756 44 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 21221479 Common - hypothetical protein SCO3036 39 COG0391 COG0391, Uncharacterized conserved protein Function unknown 21218695 Common - hypothetical protein SCO0135 40 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21224243 Nonpathogen - hypothetical protein SCO5904 1 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 21223457 Common - ketoacyl reductase SCO5086 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21225595 Common - oxidoreductase SCO7319 179 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 21223450 Common - hypothetical protein SCO5079 73 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21225740 Common - phenylacetic acid degradation protein PaaB SCO7472 38 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 21225507 Common - two-component system response regulator SCO7230 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21224219 Common - potassium uptake protein SCO5876 120 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 21225523 Common - hypothetical protein SCO7246 6 None None None 21219963 Common - inositol-5-monophosphate dehydrogenase SCO1461 239 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 21225375 Common - transcriptional regulator SCO7093 38 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 21222459 Nonpathogen - secreted protein SCO4056 1 None None None 21223259 Common - lipoprotein SCO4885 108 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 21222307 Common - hypothetical protein SCO3900 22 COG1695 COG1695, Predicted transcriptional regulators Transcription 21223719 Common rpmE 50S ribosomal protein L31 SCO5359 202 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 21218668 Common - hydrolase SCO0104 55 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 21225159 Nonpathogen - hypothetical protein SCO6868 1 None None None 21222321 Common - transcriptional regulator SCO3914 43 COG1846 MarR, Transcriptional regulators Transcription 21223709 Nonpathogen - excisionase SCO5348 3 None None None 21222387 Nonpathogen - hypothetical protein SCO3983 1 None None None 21224879 Common - hypothetical protein SCO6578 10 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21222966 Common - polyprenyl diphosphate synthase SCO4583 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 21223264 Common deoA thymidine phosphorylase SCO4890 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 21224378 Common - ABC transporter ATP-binding protein SCO6047 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21221076 Common - ATP dependent Clp protease proteolytic subunit 1 SCO2619 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21225906 Common - tetR-family transcriptional regulator SCO7645 6 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 21222294 Common - partitioning or sporulation protein SCO3887 182 COG1475 Spo0J, Predicted transcriptional regulators Transcription 21222107 Common - transcriptional regulator SCO3694 80 COG0789 SoxR, Predicted transcriptional regulators Transcription 21221481 Common - hypothetical protein SCO3038 13 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 21222023 Common - secreted protein SCO3607 32 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 21225951 Common - lyase SCO7691 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 21221816 Common - TmrB-like protein SCO3388 11 None None None 21223128 Nonpathogen - secreted protein SCO4749 2 None None None 21223304 Common - enoyl-CoA hydratase SCO4930 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21225718 Common - membrane protein SCO7449 4 None None None 21221795 Common - exporter SCO3366 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220589 Common - endonuclease SCO2111 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 21221809 Common - pantothenate kinase SCO3380 132 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 21224205 Common - two-component regulator CutR SCO5862 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21225941 Common - AMP-binding ligase SCO7681 220 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 21222231 Common - serine/threonine protein kinase SCO3821 154 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21218837 Common - regulatory protein SCO0287 62 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21219625 Common - hypothetical protein SCO1111 2 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 21220397 Nonpathogen - alanine-rich protein SCO1910 1 None None None 21224918 Common - hypothetical protein SCO6620 41 COG1846 MarR, Transcriptional regulators Transcription 21225234 Common - hypothetical protein SCO6947 7 None None None 21222424 Common - two component system histidine kinase SCO4021 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21221020 Common - long-chain fatty-acid CoA ligase SCO2561 215 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 21223817 Common - enoyl-coA hydratase SCO5459 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21220556 Common ileS isoleucyl-tRNA synthetase SCO2076 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21219776 Common - acyltransferase SCO1268 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 21220527 Nonpathogen - integral membrane efflux protein SCO2046 2 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219794 Common - oxidoreductase SCO1286 58 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21222336 Nonpathogen - hypothetical protein SCO3930 2 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21225531 Common - myo-inositol dehydrogenase SCO7254 101 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21220079 Common - ATP/GTP binding protein SCO1582 10 None None None 21224449 Common - hypothetical protein SCO6122 4 COG5500 COG5500, Predicted integral membrane protein Function unknown 21221268 Nonpathogen - hypothetical protein SCO2818 3 None None None 21223532 Nonpathogen - hypothetical protein SCO5163 1 None None None 32141270 Common infB translation initiation factor IF-2 SCO5706 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 21225640 Common - hypothetical protein SCO7366 8 None None None 21223159 Common gabD2 succinic semialdehyde dehydrogenase SCO4780 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21222718 Common - hypothetical protein SCO4326 39 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 21219808 Common - exonuclease SCO1301 123 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 21222764 Common - integral membrane protein SCO4374 52 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 21220795 Nonpathogen - hypothetical protein SCO2327 2 None None None 21219591 Nonpathogen - secreted protein SCO1076 1 None None None 21222375 Common - hypothetical protein SCO3971 22 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 32141277 Common - phosphoenolpyruvate-utilizing enzyme SCO5896 162 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 32141121 Common frcK putative fructose transport system kinase SCO0723 40 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 21226012 Nonpathogen - hypothetical protein SCO7756 1 None None None 21224793 Common - hypothetical protein SCO6489 83 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 21218735 Nonpathogen - hypothetical protein SCO0178 3 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21222915 Nonpathogen - septum determining protein SCO4531 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 21222994 Nonpathogen - hypothetical protein SCO4611 1 None None None 21225612 Nonpathogen - hypothetical protein SCO7337 1 None None None 21220070 Common - secreted protein SCO1572 34 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 21224549 Common - hypothetical protein SCO6227 44 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 32141189 Common - hypothetical protein SCO3046 58 COG1316 LytR, Transcriptional regulator Transcription 21222659 Common - oxidoreductase SCO4266 159 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21223635 Nonpathogen - hypothetical protein 2SC7G1130 SCO5268 1 None None None 21225848 Common - transcriptional regulator SCO7584 13 COG1309 AcrR, Transcriptional regulator Transcription 21222831 Common - merR-family transcriptional regulator SCO4443 13 COG0789 SoxR, Predicted transcriptional regulators Transcription 21225985 Common - hydrolase SCO7726 84 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 21219325 Common - RNA polymerase sigma factor SCO0803 55 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 32141210 Common - two-component system response regulator SCO3590 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21224657 Common - secreted amidase SCO6344 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 21219540 Common - hypothetical protein SCO1024 82 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 21221143 Common - riboflavin-specific deaminase SCO2688 227 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 21219054 Common - oxidoreductase SCO0519 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21219434 Common - hypothetical protein SCO0915 42 COG3360 COG3360, Uncharacterized conserved protein Function unknown 21221695 Common - hypothetical protein SCO3262 4 COG1403 McrA, Restriction endonuclease Defense mechanisms 21221236 Common - hypothetical protein SCO2785 49 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 21224835 Common - nitrate reductase delta chain NarJ SCO6533 57 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 21220386 Common - integral membrane sugar transport protein SCO1899 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21219488 Common - dehydrogenase/reductase (secreted protein) SCO0970 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21224935 Common - hypothetical protein SCO6638 23 COG3472 COG3472, Uncharacterized conserved protein Function unknown 21224979 Common - ABC transporter ATP-binding protein SCO6683 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21219926 Common - glycosyl transferase SCO1423 184 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21221917 Common - aldolase SCO3495 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 21225823 Common - secreted sugar hydrolase SCO7559 10 None None None 21224067 Nonpathogen - hypothetical protein SCO5720 3 None None None 21225521 Common - acyl-CoA synthetase SCO7244 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 32141126 Common - hypothetical protein SCO0913 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 21221101 Common - lysR-family transcriptional regulator SCO2644 167 COG0583 LysR, Transcriptional regulator Transcription 21224605 Common - regulatory protein SCO6286 19 COG1309 AcrR, Transcriptional regulator Transcription 21219175 Common - Zinc-containing dehydrogenase SCO0645 123 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 32141098 Common - secreted protein SCO0072 77 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 32141179 Nonpathogen - secreted protein SCO2716 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 32141190 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit PurK SCO3060 189 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 21220362 Nonpathogen - hypothetical protein SCO1874 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220487 Common - hypothetical protein SCO2005 79 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 21222343 Nonpathogen - thiamin biosynthesis protein ThiC SCO3938 1 None None None 21219600 Common - acyltransferase SCO1085 138 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21220826 Common - two-component system response regulator SCO2358 143 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21222090 Common - purine phosphoribosyltransferase SCO3677 60 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 21224734 Common - integral membrane transport protein SCO6427 97 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221126 Common - O-methyltransferase SCO2670 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 21225513 Common - ubiquinol-cytochrome C reductase cytochrome subunit B SCO7236 146 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 21225725 Nonpathogen - hypothetical protein SCO7456 1 None None None 21220599 Common - two-component system sensor kinase SCO2121 14 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21225500 Common - monooxygenase SCO7223 67 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21223995 Nonpathogen - hypothetical protein SCO5644 2 None None None 21221850 Common - regulator SCO3423 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21225790 Common - hypothetical protein SCO7524 24 COG5637 COG5637, Predicted integral membrane protein Function unknown 21224027 Common - regulatory protein SCO5678 28 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21225032 Common - carboxypeptidase (secreted protein) SCO6738 18 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 21221003 Common - IclR-family transcriptional regulator SCO2544 119 COG1414 IclR, Transcriptional regulator Transcription 21222096 Nonpathogen - secreted protein SCO3683 1 None None None 21224356 Common - transferase SCO6024 208 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21224432 Common - acetyltransferase SCO6103 30 COG0456 RimI, Acetyltransferases General function prediction only 21219423 Nonpathogen - hypothetical protein SCO0903 2 COG1695 COG1695, Predicted transcriptional regulators Transcription 21220696 Nonpathogen - hypothetical protein SCO2224 1 None None None 21224908 Common - secreted protein SCO6610 12 None None None 21218793 Common - oxidoreductase SCO0240 111 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21222540 Common - phosphate-binding protein precursor SCO4142 141 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 21222956 Common - NADH dehydrogenase subunit L SCO4573 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 21220049 Nonpathogen - small membrane protein SCO1550 1 None None None 21219536 Common - integral membrane protein SCO1019 56 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21222676 Common - sugar kinase SCO4283 90 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 21224770 Common - transferase SCO6466 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 21224708 Common - IS117 transposase SCO6400 28 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219131 Nonpathogen - anti anti sigma factor SCO0598 1 None None None 21221249 Common - cellobiose hydrolase SCO2798 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 32141108 Common - secreted protein SCO0342 12 None None None 21221945 Nonpathogen - hypothetical protein SCO3524 1 None None None 21222996 Common - integral membrane protein SCO4613 19 COG2261 COG2261, Predicted membrane protein Function unknown 21222120 Nonpathogen - lipoprotein SCO3707 1 None None None 21223005 Nonpathogen - integral membrane protein SCO4622 1 None None None 21219000 Common - hypothetical protein SCO0459 61 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 21219020 Common - secreted chitin binding protein SCO0481 23 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 21224849 Nonpathogen - very hypothetical protein SC5C732 SCO6547 1 None None None 21222188 Common - peptidase SCO3777 234 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 21222380 Common - phosphodiesterase SCO3976 153 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 21222099 Common - hypothetical protein SCO3686 4 None None None 21224060 Common - ABC transporter ATP-binding protein SCO5712 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21221152 Nonpathogen - secreted protein SCO2697 4 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 21221402 Common - hypothetical protein SCO2957 2 None None None 21220592 Common - hypothetical protein SCO2114 9 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 21223010 Nonpathogen - hypothetical protein SCO4627 1 None None None 21223370 Nonpathogen - hypothetical protein SCO4997 1 None None None 21219979 Common - DNA-directed RNA polymerase subunit omega SCO1478 24 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 21225257 Common - membrane transport protein SCO6970 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221388 Common - sugar hydrolase SCO2943 56 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 21224777 Common - crotonyl CoA reductase SCO6473 184 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21218717 Common - DNA-binding protein SCO0160 10 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21218872 Nonpathogen - hypothetical protein SCO0325 1 None None None 21222782 Common - esterase SCO4392 66 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225586 Nonpathogen - regulatory protein SCO7310 12 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 21224086 Common - hypothetical protein SCO5740 11 None None None 21222483 Nonpathogen - hypothetical protein SCO4081 5 COG0640 ArsR, Predicted transcriptional regulators Transcription 21222369 Common - hypothetical protein SCO3965 54 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 21224032 Common - two-component system sensor kinase SCO5683 131 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223836 Common - oligopeptide ABC transporter ATP-binding protein SCO5479 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21222710 Nonpathogen - hypothetical protein SCO4317 1 None None None 21220146 Nonpathogen - secreted protein SCO1650 1 None None None 32141101 Common - transmembrane transport protein SCO0152 11 COG4147 DhlC, Predicted symporter General function prediction only 21218808 Common - short chain oxidoreductase SCO0256 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21218742 Common - geranylgeranyl pyrophosphate synthase SCO0185 52 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 21223980 Common tsf elongation factor Ts SCO5625 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 21223252 Common - glycosyltransferase SCO4878 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21224744 Common - diaminopimelate decarboxylase SCO6438 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 21219722 Common - ligase SCO1212 55 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 32141232 Common - aminoglycoside phosphotransferase SCO4264 30 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 21223767 Common - hypothetical protein SCO5407 25 COG2013 COG2013, Uncharacterized conserved protein Function unknown 21220813 Nonpathogen - peptidodoglycan-binding membrane protein SCO2345 2 COG5099 COG5099, RNA-binding protein of the Puf family, translational repressor Translation, ribosomal structure and biogenesis 21220582 Nonpathogen - hypothetical protein SCO2102 1 None None None 21222925 Nonpathogen - hypothetical protein SCO4541 3 None None None 21220604 Common - glucokinase SCO2126 165 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21224117 Common - hypothetical protein SCO5771 49 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 21220958 Nonpathogen - secreted protein SCO2496 1 None None None 21221220 Nonpathogen - hypothetical protein SCO2768 1 None None None 21219066 Common - sugar transporter sugar binding protein SCO0531 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21222100 Nonpathogen - hypothetical protein SCO3687 1 None None None 21224104 Common - transcriptional regulator SCO5758 50 COG0640 ArsR, Predicted transcriptional regulators Transcription 21220081 Common - hypothetical protein SCO1584 9 None None None 21224141 Common - hypothetical protein SCO5796 224 COG2262 HflX, GTPases General function prediction only 21224223 Nonpathogen - RedY protein SCO5880 2 None None None 21218889 Common - probable IclR family regulator (secreted protein) SCO0345 94 COG1414 IclR, Transcriptional regulator Transcription 21219452 Nonpathogen - lipoprotein SCO0933 1 None None None 21219858 Common - Xaa-Pro aminopeptidase II SCO1352 225 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 21221082 Common - hypothetical protein SCO2625 18 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 21221348 Common - hypothetical protein SCO2901 213 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 21222666 Common - metallopeptidase SCO4273 139 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 21223121 Common - hypothetical protein SCO4742 164 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 21221163 Nonpathogen - integral membrane protein SCO2708 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 21222004 Common - regulatory protein SCO3587 5 COG1309 AcrR, Transcriptional regulator Transcription 21223098 Common rplR 50S ribosomal protein L18 SCO4718 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 21224255 Nonpathogen - hypothetical protein SCO5916 3 None None None 32141201 Common - pantoate-amino acid ligase SCO3383 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 21225934 Common - secreted metal-binding protein SCO7674 26 COG3794 PetE, Plastocyanin Energy production and conversion 21220168 Nonpathogen - hypothetical protein SCO1672 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 21224391 Common - oxidoreductase SCO6061 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 21224622 Common - oxidoreductase SCO6304 47 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21225029 Common - hypothetical protein SCO6735 8 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 21219629 Common - hypothetical protein SCO1115 12 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 21220050 Common - eukaryotic-type protein kinase SCO1551 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21223150 Common - inositol-5-monophosphate dehydrogenase SCO4771 223 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 21218946 Common - 2-haloalkanoic acid dehalogenase SCO0404 54 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 21224540 Nonpathogen - hypothetical protein SCO6217 1 None None None 21220166 Common - oxidoreductase SCO1670 180 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21222310 Common - hypothetical protein SCO3903 4 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 21220311 Common - transmembrane transport protein SCO1822 167 COG4147 DhlC, Predicted symporter General function prediction only 21220788 Nonpathogen - hypothetical protein SCO2320 5 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21220851 Nonpathogen - hypothetical protein SCO2384 1 None None None 21218703 Common - hypothetical protein SCO0144 7 None None None 21222015 Common - hypothetical protein SCO3599 18 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21224467 Nonpathogen - transmembrane protein SCO6141 1 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21224662 Common - transcriptional regulator SCO6349 127 COG1609 PurR, Transcriptional regulators Transcription 21225182 Nonpathogen - hypothetical protein SCO6891 1 None None None 32141137 Common - adenylosuccinate lyase SCO1254 220 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 21219384 Common - integral membrane protein SCO0863 62 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 32141172 Common - efflux protein SCO2498 223 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 32141180 Common - regulator SCO2730 6 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 21225986 Common - marR-family regulatory protein SCO7727 38 COG1846 MarR, Transcriptional regulators Transcription 21221910 Common - aldehyde dehydrogenase SCO3486 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21221261 Common - regulator SCO2811 32 COG0640 ArsR, Predicted transcriptional regulators Transcription 21223592 Common - araC-family transcriptional regulator SCO5224 116 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 32141167 Nonpathogen - secreted protein SCO2413 2 None None None 21221892 Common - transposase SCO3468 28 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 21221897 Common - aldolase SCO3473 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 21219522 Common - insertion element SCO1005 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220450 Common - export associated protein SCO1965 27 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21219576 Common - bifunctional protein (secreted sugar binding protein/sugar hydrolase) SCO1061 14 None None None 21224088 Nonpathogen - hypothetical protein SCO5742 1 None None None 21225271 Common - hypothetical protein SCO6985 14 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 21221750 Common hemA glutamyl-tRNA reductase SCO3319 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 21220144 Common - AAA ATPase SCO1648 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 21221861 Common - transcriptional regulator SCO3435 184 COG0583 LysR, Transcriptional regulator Transcription 21221640 Common - MarR-family transcriptional repressor SCO3205 55 COG1846 MarR, Transcriptional regulators Transcription 21224415 Common - transport system integral membrane protein SCO6086 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222705 Common - hypothetical protein SCO4312 30 COG4339 COG4339, Uncharacterized protein conserved in bacteria Function unknown 21221516 Common - transcriptional regulator SCO3075 65 COG1737 RpiR, Transcriptional regulators Transcription 21223324 Common - aldoketoreductase SCO4951 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21218768 Common - hypothetical protein SCO0214 7 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 32141276 Common - response regulator SCO5881 169 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221458 Common - integral membrane protein SCO3015 8 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 21222481 Common - phosphoribosylformylglycinamidine synthase II SCO4079 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 21224258 Nonpathogen - hypothetical protein SCO5919 1 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 21218815 Common - transcriptional regulator SCO0264 16 COG1846 MarR, Transcriptional regulators Transcription 21222122 Common - ECF sigma factor SCO3709 54 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21223807 Common - ABC transporter SCO5449 211 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21220431 Common pgk phosphoglycerate kinase SCO1946 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 21222040 Common - hypothetical protein SCO3625 4 None None None 21225220 Nonpathogen - hypothetical protein SCO6933 1 None None None 21222266 Nonpathogen - regulatory protein SCO3857 1 None None None 21221901 Common - dehydrogenase SCO3477 203 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 21222140 Common - hypothetical protein SCO3728 5 None None None 21225030 Common - metallopeptidase SCO6736 133 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 21223015 Common - hypothetical protein SCO4633 36 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21225332 Common - glutaminase SCO7049 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 21220413 Common - aminoglycoside acetyltransferase SCO1927 22 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 21224079 Nonpathogen - hypothetical protein SCO5732 1 None None None 21220584 Common thiE thiamine-phosphate pyrophosphorylase SCO2104 124 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 21222967 Nonpathogen - hypothetical protein SCO4584 5 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 32141332 Common - cytochrome P450 (fragment) SCO7444 45 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21221417 Common prfB peptide chain release factor 2 SCO2972 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 21223757 Common - large Ala/Glu-rich protein SCO5397 26 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 21225328 Common - hypothetical protein SCO7045 50 COG1993 COG1993, Uncharacterized conserved protein Function unknown 21225999 Common - hypothetical protein SCO7740 6 None None None 21223084 Common - 50S ribosomal protein L23 SCO4704 170 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 21223795 Common - sodium:dicarboxylate symporter SCO5436 155 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 21222796 Common - hypothetical protein SCO4407 10 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 21218757 Common - integral membrane protein SCJ1213c SCO0201 4 None None None 21221108 Common - dehydrogenase/reductase (secreted protein) SCO2651 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21223424 Common - glycosyltransferase SCO5051 154 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21223545 Common - reductase SCO5176 29 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21223517 Common - hypothetical protein SCO5148 4 None None None 21219571 Common - sugar transport sugar binding protein SCO1056 108 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21219720 Common - transcriptional regulatory protein SCO1210 17 COG1309 AcrR, Transcriptional regulator Transcription 21222354 Common - secreted peptidase SCO3949 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21220945 Common - dehydrogenase (secreted protein) SCO2482 12 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 21222978 Common - oxidoreductase SCO4595 106 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 21224385 Common - probable carbonic anhydrase SCO6055 151 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 21223846 Common - hypothetical protein SCO5490 52 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 21219806 Common - transcriptional regulatory protein SCO1299 157 COG1522 Lrp, Transcriptional regulators Transcription 21224269 Common - NTP pyrophosphohydrolase SCO5930 51 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 21225608 Common - hypothetical protein SCO7333 57 COG3281 Ble, Uncharacterized protein, probably involved in trehalose biosynthesis Carbohydrate transport and metabolism 21222167 Common - two component system response regulator SCO3756 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220107 Nonpathogen - hypothetical protein SCO1610 3 None None None 21219374 Nonpathogen - membrane protein SCO0853 1 None None None 21220295 Common - hypothetical protein SCO1805 14 COG3953 COG3953, SLT domain proteins General function prediction only 21222698 Common - hypothetical protein SCO4305 12 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 21225899 Common - enolase SCO7638 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 21219118 Common - ATP/GTP binding protein SCO0585 28 COG2229 COG2229, Predicted GTPase General function prediction only 21221194 Common - sigma factor SCO2742 56 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 32141262 Common - phosphate acetyltransferase SCO5425 170 COG0280 Pta, Phosphotransacetylase Energy production and conversion 21224232 Common - 8-amino-7-oxononanoate synthase SCO5890 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 21220643 Common - integral membrane protein SCO2169 19 None None None 21224133 Common - hypothetical protein SCO5788 9 None None None 21222908 Nonpathogen - integral membrane protein SCO4523 1 None None None 21224369 Common - transmembrane transport protein SCO6037 17 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21224485 Common - gntR family transcriptional regulator SCO6159 120 COG1802 GntR, Transcriptional regulators Transcription 21221780 Common - DNA repair protein RadA SCO3351 201 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 21225672 Common - hypothetical protein SCO7401 48 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 21224562 Nonpathogen - hypothetical protein SCO6241 1 None None None 21220480 Common rpsA 30S ribosomal protein S1 SCO1998 224 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 21223622 Nonpathogen - signal peptidase protein SCO5255 9 COG2932 COG2932, Predicted transcriptional regulator Transcription 21224149 Common - hypothetical protein SCO5804 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 21223286 Common - aldehyde dehydrogenase SCO4912 181 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21219841 Common - oxidoreductase SCO1335 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21225215 Nonpathogen - hypothetical protein SCO6927 3 None None None 21224354 Common - hypothetical protein SCO6022 7 None None None 21220005 Common - regulator SCO1504 27 COG3903 COG3903, Predicted ATPase General function prediction only 21219203 Nonpathogen - hypothetical protein SCO0673 3 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21221872 Common - transcriptional regulatory protein SCO3447 59 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 21219403 Common def peptide deformylase SCO0883 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 21219873 Common - ABC transport system transmembrane protein SCO1368 13 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 21224847 Common - secreted cellulase SCO6545 37 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 32141310 Common - glycosyl transferase SCO6651 155 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21222022 Common - regulator SCO3606 26 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 21223418 Common - hypothetical protein SCO5045 16 None None None 21219943 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein SCO1441 217 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 21225016 Common - regulator SCO6722 8 None None None 21219602 Common - aldolase SCO1087 119 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 21225655 Nonpathogen - hypothetical protein SCO7382 1 None None None 21224074 Nonpathogen - hypothetical protein SCO5727 1 None None None 21224220 Common - transcriptional regulator RedD SCO5877 15 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21219235 Common - branched-chain amino acid transport ATP-binding protein SCO0709 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 21221392 Common - hypothetical protein SCO2947 19 None None None 32141182 Common - hypothetical protein SCO2810 13 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 21221599 Common - esterase SCO3162 51 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21225116 Common - ArsR-family transcriptional regulator SCO6823 37 COG1777 COG1777, Predicted transcriptional regulators Transcription 21223130 Common - acetyltransferase SCO4751 76 COG0456 RimI, Acetyltransferases General function prediction only 21225651 Common - hypothetical protein SCO7378 10 None None None 21220890 Nonpathogen - secreted protein SCO2425 1 None None None 21220748 Common - hypothetical protein SCO2279 5 None None None 21224805 Nonpathogen - gas vesicle synthesis protein SCO6502 1 None None None 21218941 Common - glycosyl transferase SCO0398 175 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21224503 Common - deacetylase (secreted protein) SCO6178 127 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21219223 Common - hypothetical protein SCO0695 20 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 32141140 Common - integral membrane protein SCO1359 68 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21223973 Nonpathogen - hypothetical protein SCO5618 1 None None None 21219332 Common - ABC transporter permease SCO0810 101 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 21221752 Common - redoxin SCO3321 19 None None None 21220135 Common - secreted peptidyl-prolyl cis-trans isomerase protein SCO1639 128 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 21219293 Common - hypothetical protein SCO0770 12 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 21222579 Common - D-tyrosyl-tRNA deacylase SCO4182 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 21223364 Common - sugar transport integral membrane protein SCO4991 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 21221068 Common - rod shape-determining protein SCO2610 137 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 21225992 Nonpathogen - transcriptional regulatory protein SCO7733 3 COG2944 COG2944, Predicted transcriptional regulator Transcription 21224124 Common - two-component system regulator SCO5778 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21225145 Nonpathogen - hypothetical protein SCO6854 1 None None None 21223963 Nonpathogen - hypothetical protein SCO5608 1 None None None 21220977 Common - secreted protein SCO2516 34 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225424 Common - ECF sigma factor SCO7144 52 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21224791 Common - hypothetical protein SCO6487 180 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 21225236 Common - hypothetical protein SCO6949 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21218967 Common - hypothetical protein SCO0425 4 None None None 21218847 Common - lysR-family transcriptional regulator SCO0298 171 COG0583 LysR, Transcriptional regulator Transcription 21224362 Common - hypothetical protein SCO6030 19 None None None 21219565 Common - secreted oxidoreductase SCO1049 123 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21221443 Common - phosphatase SCO3000 9 COG0546 Gph, Predicted phosphatases General function prediction only 21224720 Common - DNA-binding protein SCO6413 21 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21225505 Common - polysaccharide lyase SCO7228 30 None None None 21223650 Common - hypothetical protein SCO5284 34 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 21218750 Common - sigma factor SCO0194 116 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21221982 Common - acetyl-CoA synthetase SCO3563 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 32141346 Common - hypothetical protein SCO7845 23 COG4889 COG4889, Predicted helicase General function prediction only 21223022 Common - tetR-family transcriptional regulator SCO4640 59 COG1309 AcrR, Transcriptional regulator Transcription 21224902 Common - transmembrane sugar transport protein SCO6602 166 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21225843 Common - DNA-binding protein SCO7579 6 COG1396 HipB, Predicted transcriptional regulators Transcription 21223959 Common - hypothetical protein SCO5604 204 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 21221868 Common - hypothetical protein SCO3442 18 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 21219865 Common - gntR-family transcriptional regulator SCO1360 114 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 21224833 Common - ATP/GTP binding protein SCO6531 66 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 21219095 Common - Fe regulatory protein SCO0561 129 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 21225841 Common - secreted hydrolase SCO7577 19 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 32141303 Common - hypothetical protein SCO6465 7 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21221653 Common - small conserved hypothetical protein SCO3218 37 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 21224099 Common - phosphatidylglycerophosphate synthase SCO5753 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 21221366 Nonpathogen - hypothetical protein SCO2919 1 None None None 21220263 Common - hypothetical protein SCO1771 5 None None None 21223503 Common - hypothetical protein SCO5133 35 COG2912 COG2912, Uncharacterized conserved protein Function unknown 21222284 Common recF recombination protein F SCO3876 173 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 21219714 Common gabD1 succinic semialdehyde dehydrogenase SCO1204 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21224388 Common - hypothetical protein SCO6058 16 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 21225414 Common - hypothetical protein SCO7132 44 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21221604 Common - tetR-family transcriptional regulator SCO3167 47 COG1309 AcrR, Transcriptional regulator Transcription 21224968 Common - hypothetical protein SCO6672 11 COG1409 Icc, Predicted phosphohydrolases General function prediction only 21225969 Common - phosphotransferase SCO7710 3 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 21219910 Common - hypothetical protein SCO1406 4 None None None 21224304 Common - hypothetical protein SCO5967 31 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 21225351 Nonpathogen - secreted protein SCO7068 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 21224882 Common - hypothetical protein SCO6582 153 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 21226078 Nonpathogen - hypothetical protein SCO7829 5 None None None 21225126 Common - thioredoxin reductase SCO6834 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 21219981 Common - hypothetical protein SCO1480 17 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 21223733 Common - F0F1 ATP synthase subunit beta SCO5373 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 21223137 Common - hypothetical protein SCO4758 25 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 32141269 Nonpathogen - ATP/GTP binding protein SCO5677 1 None None None 21221137 Common - hypothetical protein SCO2682 2 None None None 21218747 Common - lycopene cyclase SCO0191 15 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21222309 Common - integral membrane protein SCO3902 17 COG5650 COG5650, Predicted integral membrane protein Function unknown 21222632 Nonpathogen - integral membrane protein SCO4237 2 COG2259 COG2259, Predicted membrane protein Function unknown 21223461 Common - actinorhodin polyketide synthase bifunctional cyclase/dehydratase SCO5090 6 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 21222846 Nonpathogen - hypothetical protein SCO4459 1 None None None 21218626 Common - transcriptional regulator SCO0047 50 COG1846 MarR, Transcriptional regulators Transcription 21219738 Common - reductase SCO1229 8 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21222400 Common - integrase SCO3997 109 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 21220838 Common - hypothetical protein SCO2370 16 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 21219749 Common - NLP/P60 family protein (secreted protein) SCO1240 129 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21223294 Common - deoR-family transcriptional regulator SCO4920 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 21221649 Common - probable anthranilate synthase component I SCO3214 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 21219933 Common - TetR-family transcriptional regulator SCO1430 56 COG1309 AcrR, Transcriptional regulator Transcription 21221384 Common - oxidoreductase SCO2938 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21225095 Common - DNA-binding protein SCO6802 41 COG1396 HipB, Predicted transcriptional regulators Transcription 21224706 Common - IS element ATP binding protein SCO6394 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 21220492 Common - branched chain amino acid transport permease SCO2010 158 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 21222445 Nonpathogen - hypothetical protein SCO4042 2 None None None 21222604 Common - integral membrane transport protein SCO4208 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220659 Nonpathogen - hypothetical protein SCO2185 1 None None None 21222184 Common - lysR family transcriptional regulatory protein SCO3773 160 COG0583 LysR, Transcriptional regulator Transcription 21219045 Common - tetR family transcriptional regulator SCO0508 21 COG1309 AcrR, Transcriptional regulator Transcription 21225106 Common - ArsR-family transcriptional regulator SCO6813 95 COG0640 ArsR, Predicted transcriptional regulators Transcription 21224954 Common - 6-phosphogluconate dehydrogenase-like protein SCO6658 188 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 21223513 Common - acyl CoA isomerase SCO5144 160 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21222514 Common - sporulation associated protein SCO4114 7 None None None 21221979 Common - ATP-binding protein SCO3560 20 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 21219034 Common - iron-siderophore permease transmembrane protein SCO0496 162 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 21221282 Common - IclR-family transcriptional regulator SCO2832 59 COG1414 IclR, Transcriptional regulator Transcription 21218798 Common - integral membrane protein SCO0245 188 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 32141324 Common - transcriptional regulator SCO7173 27 COG3899 COG3899, Predicted ATPase General function prediction only 21218823 Common - binding-protein-dependent transport protein SCO0272 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21224296 Common - cobalt transport system ATP binding protein SCO5958 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 21218678 Common - short chain dehydrogenase SCO0117 214 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21222878 Common - octaprenyl carboxylase SCO4492 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 21219080 Common - secreted protein SCO0545 17 None None None 21222948 Common - NADH dehydrogenase subunit D SCO4565 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 21225131 Nonpathogen - hypothetical protein SCO6839 3 None None None 21220681 Nonpathogen - transcriptional regulator SCO2209 3 COG1846 MarR, Transcriptional regulators Transcription 21220865 Nonpathogen - marR-family transcriptonal regulator SCO2398 5 COG1846 MarR, Transcriptional regulators Transcription 21225544 Common - hypothetical protein SCO7267 44 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21221242 Nonpathogen - hypothetical protein SCO2791 1 None None None 21223688 Nonpathogen - hypothetical protein SCO5325 2 COG1733 COG1733, Predicted transcriptional regulators Transcription 21225776 Common - peptidyl-prolyl cis-trans isomerase SCO7510 189 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 21219481 Common - hypothetical protein SCO0963 4 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 21224305 Nonpathogen - bldA-regulated nucleotide binding protein SCO5968 2 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 21218642 Common - integral membrane permease SCO0067 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21224607 Common - regulatory protein SCO6288 14 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21224294 Common - regulatory protein SCO5956 6 COG1309 AcrR, Transcriptional regulator Transcription 21224751 Common - inositol monophosphatase SCO6445 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 21225083 Common - long chain fatty acid coA ligase SCO6790 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 21220997 Common - hypothetical protein SCO2538 10 None None None 21223663 Common - hypothetical protein SCO5300 16 None None None 21223982 Common - ribosome recycling factor SCO5627 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 21225280 Common - hypothetical protein SCO6994 6 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 21221423 Common - integral membrane transport protein SCO2979 117 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21226067 Common - oxidoreductase SCO7818 149 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 21219283 Common - hypothetical protein SCO0759 13 None None None 21220345 Common - bifunctional protein (CbiGH) SCO1857 118 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 21224764 Common - hypothetical protein SCO6458 57 COG1801 COG1801, Uncharacterized conserved protein Function unknown 21225761 Common - hypothetical protein SCO7493 45 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 21219217 Nonpathogen - hypothetical protein SCO0688 1 None None None 21218865 Common - transmembrane transport protein SCO0317 6 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21219908 Common - hypothetical protein SCO1404 10 None None None 21223961 Nonpathogen - hypothetical protein SCO5606 1 None None None 21218609 Nonpathogen - hypothetical protein SCO0030 1 None None None 21222254 Common - protein phosphatase SCO3845 136 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 21219090 Common - hypothetical protein SCO0556 18 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21221557 Nonpathogen - hypothetical protein SCO3118 2 None None None 21224049 Common - kinase SCO5700 8 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 21218958 Nonpathogen - probable integral membrane protein SCO0416 3 None None None 21222814 Common - regulatory protein SCO4426 27 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 21224691 Common - hypothetical protein SCO6379 114 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21225667 Common - secreted protein SCO7396 22 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 21222074 Nonpathogen - hypothetical protein SCO3659 2 None None None 21225578 Common - hypothetical protein SCO7302 39 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 21221717 Common - large glycine/alanine rich protein SCO3285 12 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 21220887 Common - ABC-transporter ATP-binding protein SCO2422 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 21219691 Common - DNA polymerase III beta chain SCO1180 67 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 21218651 Common - hypothetical protein SCO0080 3 None None None 21223142 Nonpathogen - hypothetical protein SCO4763 1 None None None 21219644 Common - hypothetical protein SCO1130 66 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 21220121 Common - ribosomal pseudouridine synthase SCO1625 214 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 21219303 Common - zinc-binding oxidoreductase SCO0780 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21222854 Nonpathogen - hypothetical protein SCO4467 1 None None None 21220900 Nonpathogen - integral membrane protein SCO2436 2 None None None 21225562 Common - hydroxylase SCO7285 42 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21219196 Common - catalase SCO0666 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 21223056 Common - hypothetical protein SCO4675 4 None None None 21219111 Common - triosephosphate isomerase SCO0578 213 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 21219328 Common - LacI-family transcriptional regulatory protein SCO0806 127 COG1609 PurR, Transcriptional regulators Transcription 21218831 Common - hypothetical protein SCO0281 9 None None None 21223245 Common - hypothetical protein SCO4870 89 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21220937 Common - metalloproteinase (secreted protein) SCO2474 43 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 21225538 Common - hypothetical protein SCO7261 11 None None None 32141259 Common - two component sensor kinase SCO5289 26 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21220233 Common - DNA polymerase III, alpha chain SCO1739 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 21220283 Nonpathogen - hypothetical protein SCO1791 1 None None None 21222556 Common - LacI-family regulatory protein SCO4158 126 COG1609 PurR, Transcriptional regulators Transcription 21224169 Common - two-component response regulator SCO5825 200 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223616 Common - nucleotide-binding protein SCO5249 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 21222957 Common - NADH dehydrogenase subunit M SCO4574 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 21221025 Common - hypothetical protein SCO2566 114 COG2353 COG2353, Uncharacterized conserved protein Function unknown 21222201 Common - hypothetical protein SCO3790 68 COG3211 PhoX, Predicted phosphatase General function prediction only 21221742 Common - delta-aminolevulinic acid dehydratase SCO3311 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 31340552 Common - hypothetical protein SCO1919 143 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 21223161 Nonpathogen - integral membrane protein SCO4782 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 21219788 Common - hypothetical protein SCO1280 13 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 21221830 Common folE GTP cyclohydrolase I SCO3403 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 21219756 Common - hypothetical protein SCO1247 94 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21223860 Nonpathogen - integral membrane protein SCO5504 1 None None None 21225121 Common - oxidoreductase SCO6829 227 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21221608 Common - hydrolase SCO3171 143 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21220475 Common - hypothetical protein SCO1993 9 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 21222929 Common - hypothetical protein SCO4545 4 None None None 21221737 Common - aminotransferase SCO3306 187 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 21221789 Nonpathogen - hypothetical protein SCO3360 4 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 21219683 Common - amidase (secreted protein) SCO1172 95 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 21222934 Nonpathogen - hypothetical protein SCO4551 1 None None None 21221304 Common - transmembrane efflux protein SCO2854 41 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21225472 Common - hypothetical protein SCO7193 54 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 21225573 Common - two-component sensor histidine kinase SCO7297 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21219753 Common - biotin synthase SCO1244 181 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 21225493 Common - FecCD-family membrane transport protein SCO7216 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 21219968 Nonpathogen - integral membrane protein SCO1466 1 None None None 21225942 Common - non-ribosomal peptide synthase SCO7682 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21219740 Common - urease accessory protein SCO1231 9 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 21218897 Common - binding protein dependent transport protein SCO0353 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21225868 Common - amino acid binding protein SCO7606 6 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 32141107 Common - ABC transport ATP-binding subunit SCO0322 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21220610 Common - integral membrane protein SCO2133 8 COG5650 COG5650, Predicted integral membrane protein Function unknown 21223236 Nonpathogen - hypothetical protein SCO4861 1 None None None 21224341 Common - probable transmembrane transport protein SCO6006 141 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21218930 Common - bi-domain oxidoreductase SCO0387 148 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21225075 Common - probable zinc-binding alcohol dehydrogenase SCO6782 188 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 21218802 Common - hypothetical protein SCO0249 130 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21225818 Common - lacI-family transcriptional regulator SCO7554 127 COG1609 PurR, Transcriptional regulators Transcription 21226058 Nonpathogen - hypothetical protein SCO7808 1 None None None 21222054 Common - two-component system sensor kinase SCO3639 75 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21221504 Common - two-component system reponse regulator SCO3063 208 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21222950 Common - NuoF, NADH dehydrogenase subunit SCO4567 172 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 21220703 Common - maltose-binding protein SCO2231 125 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 21222081 Common - secreted solute-binding protein SCO3667 99 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 21222497 Nonpathogen - lipoprotein SCO4095 1 None None None 21220197 Common - transcriptional regulator SCO1702 49 COG1309 AcrR, Transcriptional regulator Transcription 21221797 Common - peptidase (secreted protein) SCO3368 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21220401 Nonpathogen - hypothetical protein SCO1914 1 None None None 21222421 Common - hypothetical protein SCO4018 125 COG1881 COG1881, Phospholipid-binding protein General function prediction only 21221689 Nonpathogen - SpdA protein SCO3256 2 None None None 21222730 Common - hypothetical protein SCO4338 25 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 21225559 Common - DNA-binding protein SCO7282 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 21219739 Common - secreted tripeptidylaminopeptidase SCO1230 38 None None None 21220876 Common - secreted protein SCO2409 18 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 21226091 Common - transposase SCO7842 35 None None None 21221329 Common - hypothetical protein SCO2880 6 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21224336 Nonpathogen - hypothetical protein SCO6000 3 None None None 21219417 Common - hypothetical protein SCO0897 32 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 21220531 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase SCO2050 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 21220899 Nonpathogen - hypothetical protein SCO2435 1 None None None 21226023 Common - hypothetical protein SCO7769 43 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21222585 Nonpathogen - hypothetical protein SCO4189 1 None None None 21221215 Common - ABC transporter protein, ATP-binding component SCO2763 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21220724 Common - transmembrane efflux protein SCO2254 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220459 Common - integral membrane protein SCO1976 21 COG5500 COG5500, Predicted integral membrane protein Function unknown 21222592 Common - organophosphate acid anhydrase SCO4196 76 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 21219630 Common - hypothetical protein SCO1116 4 None None None 21225734 Common - hypothetical protein SCO7465 9 None None None 161353678 Common - cobalt transport protein CbiM SCO5961 65 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 21220625 Common - cytochrome B subunit SCO2148 143 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 21223493 Nonpathogen - small membrane protein SCO5123 1 None None None 21222828 Nonpathogen - hypothetical protein SCO4440 4 None None None 21225448 Common - gntR-family transcriptional regulator SCO7168 94 COG1802 GntR, Transcriptional regulators Transcription 21222523 Common - two-component sensor kinase SCO4124 75 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21225485 Nonpathogen - hypothetical protein SCO7208 1 None None None 21219310 Common - secreted hydrolase SCO0787 54 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 21223317 Common - DNA-binding protein SCO4944 41 COG1396 HipB, Predicted transcriptional regulators Transcription 21224246 Nonpathogen - hypothetical protein SCO5907 1 None None None 21218775 Common - acetyltransferase SCO0222 88 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21221331 Common - conserved ATP/GTP-binding protein SCO2882 29 COG2229 COG2229, Predicted GTPase General function prediction only 21222917 Nonpathogen - hypothetical protein SCO4533 1 None None None 21221368 Nonpathogen - hypothetical protein SCO2921 1 None None None 21222639 Nonpathogen - hypothetical protein SCO4244 20 None None None 21225398 Common - hypothetical protein SCO7116 19 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 21220357 Common - hypothetical protein SCO1869 79 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 32141208 Common - serine protease SCO3567 139 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 21221678 Common - salicylate hydroxylase (secreted protein) SCO3245 85 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21218615 Nonpathogen - hypothetical protein SCO0036 1 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 21224533 Common - hypothetical protein SCO6209 9 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 21220803 Common - integral membrane protein SCO2335 9 COG5650 COG5650, Predicted integral membrane protein Function unknown 21222819 Common - integral membrane protein SCO4431 19 COG5472 COG5472, Predicted small integral membrane protein Function unknown 21224516 Common - hypothetical protein SCO6192 14 None None None 21219391 Common - two-component system response regulator SCO0870 216 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220519 Nonpathogen - hypothetical protein SCO2038 1 None None None 21220013 Common - GTP pyrophosphokinase SCO1513 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 21223376 Common - chinitase A precursor SCO5003 25 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 21224924 Common - protein kinase SCO6626 67 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21221465 Nonpathogen - hypothetical protein SCO3022 1 None None None 21220897 Common - sugar transporter membrane protein SCO2433 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21218888 Common - GntR family DNA-binding regulator SCO0344 138 COG1802 GntR, Transcriptional regulators Transcription 21221680 Common - acyl CoA oxidase SCO3247 82 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21221926 Common - secreted substrate binding protein SCO3505 102 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21218593 Common - hypothetical protein SCO0011 3 None None None 21219012 Common - secreted protein SCO0472 16 None None None 21223899 Common - membrane protein SC1C225c SCO5544 78 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21221379 Common - permease membrane component SCO2932 148 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 21224913 Nonpathogen - hypothetical protein SCO6615 1 None None None 21225631 Common - probable dioxygenase SCO7357 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 21224869 Common - ABC transporter integral membrane protein SCO6568 105 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 21225694 Common - MarR-family transcriptional regulator SCO7424 10 COG1846 MarR, Transcriptional regulators Transcription 21218809 Common - hypothetical protein SCO0257 21 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 21224050 Nonpathogen - hypothetical protein SCO5701 2 None None None 21219083 Common - 3-oxoacyl-(ACP) synthase SCO0548 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222763 Common - mut-like protein SCO4373 67 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21223692 Common - hypothetical protein SCO5330 4 None None None 21225495 Common - iron transport lipoprotein SCO7218 88 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 21220683 Nonpathogen - hypothetical protein SCO2211 2 None None None 21225617 Nonpathogen - hypothetical protein SCO7342 1 None None None 21219341 Common - hypothetical protein SCO0820 16 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 21222179 Nonpathogen - translocase protein SCO3768 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 21225741 Common - phenylacetic acid degradation protein PaaC SCO7473 42 COG3396 COG3396, Uncharacterized conserved protein Function unknown 21225207 Nonpathogen - hypothetical protein SCO6919 1 None None None 21219460 Common - lipoprotein SCO0941 71 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 21219192 Common - binding protein dependent transport protein SCO0662 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21223346 Common - hypothetical protein SCO4973 67 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 21223219 Nonpathogen - integral membrane protein SCO4843 2 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21221544 Nonpathogen - hypothetical protein SCO3105 1 None None None 21219298 Common - hypothetical protein SCO0775 11 None None None 21219875 Common - two component system DNA binding response regulator SCO1370 148 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220606 Common - hypothetical protein SCO2129 9 None None None 21219317 Common - hypothetical protein SCO0795 8 None None None 21225200 Common - insertion element transposase SCO6910 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219653 Nonpathogen - integral membrane protein SCO1139 3 None None None 21220322 Nonpathogen - hypothetical protein SCO1833 1 None None None 21220503 Common - hypothetical protein SCO2021 16 COG2968 COG2968, Uncharacterized conserved protein Function unknown 21221160 Nonpathogen - hypothetical protein SCO2705 1 None None None 21225830 Common - oligopeptide ABC transporter ATP-binding protein SCO7566 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21221614 Nonpathogen - hypothetical protein SCO3177 3 COG3619 COG3619, Predicted membrane protein Function unknown 21221446 Nonpathogen - hypothetical protein SCO3003 1 None None None 21221603 Common - membrane transport protein SCO3166 38 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21221017 Nonpathogen - hypothetical protein SCO2558 10 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 21222515 Common - AfsR-like regulatory protein SCO4116 28 COG3903 COG3903, Predicted ATPase General function prediction only 21220741 Common - binding-protein-dependent transport lipoprotein SCO2272 117 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 21223076 Nonpathogen - hypothetical protein SCO4696 2 None None None 21223773 Common - MarR-transcriptional regulator SCO5413 76 COG1846 MarR, Transcriptional regulators Transcription 21219156 Nonpathogen - secreted protein SCO0624 2 None None None 21218923 Common - hypothetical protein SCO0380 66 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 21220201 Common - aldehyde dehydrogenase SCO1706 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 32141220 Common - hypothetical protein SCO3918 8 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 21220508 Common - hypothetical protein SCO2027 68 COG1814 COG1814, Uncharacterized membrane protein Function unknown 21219003 Common - hypothetical protein SCO0463 14 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21220180 Common - integral membrane protein SCO1685 8 None None None 21223607 Common - hypothetical protein SCO5240 19 None None None 21221013 Common - DnaJ protein SCO2554 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 32141225 Common - oxidoreductase SCO4109 184 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21219987 Common pyrC dihydroorotase SCO1486 214 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 21219860 Nonpathogen - secreted protein SCO1354 1 None None None 21219244 Nonpathogen - hypothetical protein SCO0718 2 None None None 161353683 Common glgC glucose-1-phosphate adenylyltransferase SCO0961 154 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 21219514 Common - Fe uptake system integral membrane protein SCO0997 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 21225687 Common - cytochrome P450-family protein SCO7417 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21220904 Common - transcriptional regulator SCO2440 120 COG1414 IclR, Transcriptional regulator Transcription 21222806 Common - acetyltransferase SCO4417 72 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21219533 Nonpathogen - secreted protein SCO1016 1 None None None 21225055 Common - phytoene dehydrogenase SCO6762 21 COG3349 COG3349, Uncharacterized conserved protein Function unknown 21222431 Common - hypothetical protein SCO4028 10 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 21224271 Common - hypothetical protein SCO5933 55 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21220009 Common hisS histidyl-tRNA synthetase SCO1508 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21218607 Nonpathogen - hypothetical protein SCO0028 1 None None None 21220538 Common - hypothetical protein SCO2057 56 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 21221300 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase SCO2850 181 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 21219469 Common - transport system permease protein SCO0951 114 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21221094 Common - serine protease (secreted protein) SCO2637 36 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21223472 Nonpathogen - hypothetical protein SCO5101 2 None None None 21226051 Common - transposase SCO7799 61 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 21220563 Common - sporulation protein SCO2083 24 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 21223486 Common - BldKD, ABC transporter intracellular ATPase subunit SCO5115 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 21219365 Common - DNA-binding protein SCO0844 13 None None None 21225166 Nonpathogen - hypothetical protein SCO6875 1 None None None 21219100 Nonpathogen - hypothetical protein SCO0566 1 None None None 21219051 Common - lipoprotein SCO0516 18 COG3391 COG3391, Uncharacterized conserved protein Function unknown 21219202 Common - anti-sigma factor antagonist SCO0672 30 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21223522 Common - integral membrane protein SCO5153 45 COG4420 COG4420, Predicted membrane protein Function unknown 21220674 Common - hypothetical protein SCO2201 123 COG1733 COG1733, Predicted transcriptional regulators Transcription 21221182 Nonpathogen - hypothetical protein, SCC4613 SCO2728 3 None None None 21222643 Common - hypothetical protein SCO4248 19 None None None 21221225 Common - acyl-CoA dehydrogenase SCO2774 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21224895 Common - secreted protein SCO6595 6 None None None 21224059 Common - bifunctional riboflavin kinase/FMN adenylyltransferase SCO5711 211 COG0196 RibF, FAD synthase Coenzyme metabolism 21224278 Common - hypothetical protein SCO5940 30 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 21224591 Common - oxidoreductase alpha-subunit SCO6270 106 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 21219429 Nonpathogen - hypothetical protein SCO0909 13 COG4295 COG4295, Uncharacterized protein conserved in bacteria Function unknown 21220301 Nonpathogen - hypothetical protein SCO1811 1 None None None 21221490 Common - hypothetical protein SCO3048 62 COG1316 LytR, Transcriptional regulator Transcription 21222737 Nonpathogen - hypothetical protein SCO4345 1 None None None 21225550 Nonpathogen - hypothetical protein SCO7273 1 None None None 21225175 Common - secreted protein SCO6884 92 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21220716 Common - hypothetical protein SCO2246 6 None None None 21221970 Nonpathogen - membrane spanning protein SCO3551 1 None None None 21224893 Common - hypothetical protein SCO6593 5 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 21223193 Nonpathogen - secreted protein SCO4815 2 None None None 21223092 Common rplN 50S ribosomal protein L14 SCO4712 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 21222060 Common - hydrolase SCO3645 63 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 21221552 Nonpathogen - hypothetical protein SCO3113 1 None None None 21220318 Common - hypothetical protein SCO1829 52 COG3346 COG3346, Uncharacterized conserved protein Function unknown 21223047 Common - ABC-transporter ATP-binding protein SCO4666 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21220443 Common uvrA excinuclease ABC subunit A SCO1958 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 21222067 Common - hypothetical protein SCO3652 4 COG3427 COG3427, Uncharacterized conserved protein Function unknown 21219491 Common - integral membrane protein SCO0973 3 COG2510 COG2510, Predicted membrane protein Function unknown 21222873 Common - serine/threonine protein kinase SCO4487 146 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21222984 Common - dehydrogenase SCO4601 167 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 32141123 Common - aldo/keto reductase SCO0769 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21224659 Common - hypothetical protein SCO6346 2 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21221477 Common - sporulation regulatory protein SCO3034 19 None None None 21223565 Common - hypothetical protein SCO5196 28 COG2013 COG2013, Uncharacterized conserved protein Function unknown 21225403 Common - secreted protein SCO7121 43 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21225921 Common - voltage-gated potassium channel SCO7660 84 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 32141294 Common - acyl-CoA carboxylase complex A subunit SCO6271 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 21222954 Common - NADH dehydrogenase subunit J SCO4571 72 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 21219784 Nonpathogen - RNA polymerase ECF sigma factor SCO1276 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225892 Common - secreted protein SCO7631 15 COG1409 Icc, Predicted phosphohydrolases General function prediction only 21223685 Common - hypothetical protein SCO5322 13 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 21221148 Common - oxygenase (secreted protein) SCO2693 10 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 21225132 Common - hypothetical protein SCO6840 7 None None None 21223479 Common - integral membrane protein SCO5108 10 None None None 21221435 Nonpathogen - hypothetical protein SCO2991 1 None None None 32141248 Common - phosphorylmutase SCO4833 44 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 21224619 Nonpathogen - hypothetical protein SCO6301 1 None None None 32141157 Common - hypothetical protein SCO2128 11 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 21225224 Nonpathogen - DNA-binding protein SCO6937 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220772 Nonpathogen - hypothetical protein SCO2303 1 None None None 21225808 Common - Crp-family transcriptional regulator SCO7543 127 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21225910 Common - two-component system sensor kinase SCO7649 68 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21223644 Nonpathogen - magnesium chelatase SCO5278 2 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 21219830 Common - 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase SCO1324 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21225647 Common - hypothetical protein SCO7373 3 None None None 21223598 Common - integral membrane protein SCO5230 13 None None None 21219854 Common - hypothetical protein SCO1348 15 None None None 32141268 Common - aldehyde dehydrogenase SCO5666 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21222580 Common - transposase SCO4183 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21224855 Common - integral membrane efflux protein SCO6553 153 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21222273 Common - hypothetical protein SCO3865 3 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21223248 Nonpathogen - hypothetical protein SCO4873 1 None None None 21220921 Common - lipoprotein SCO2457 2 None None None 21223157 Common - serine/threonine protein kinase SCO4778 150 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21225575 Common - stress-inducible protein SCO7299 15 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21225706 Common - probable aldehyde dehydrogenase SCO7436 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21218729 Common - hypothetical protein SCO0172 18 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21221633 Common - deoR-family transcriptional regulator SCO3198 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 21223290 Common - phosphomannomutase SCO4916 237 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 21223107 Common - 30S ribosomal protein S11 SCO4728 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 21225148 Nonpathogen - hypothetical protein SCO6857 1 None None None 21223738 Common - chitinase two-component sensor kinase SCO5378 100 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21224610 Common - secreted oxidase SCO6291 90 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 21223509 Common - hypothetical protein SCO5140 149 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 21222773 Common - 4-coumarate:CoA ligase SCO4383 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21225928 Common - hypothetical protein SCO7668 10 COG2345 COG2345, Predicted transcriptional regulator Transcription 21219229 Common - regulator SCO0702 7 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 21222685 Common - hypothetical protein SCO4292 52 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21220980 Common - integral membrane protein SCO2519 44 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225348 Nonpathogen - hypothetical protein SCO7065 1 None None None 21220477 Common - hypothetical protein SCO1995 5 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 21225696 Nonpathogen - hypothetical protein SCO7426 3 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 21224634 Common - hypothetical protein SCO6318 18 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21222143 Common - cold-shock protein SCO3731 180 COG1278 CspC, Cold shock proteins Transcription 21220353 Common - diaminobutyrate--2-oxoglutarate aminotransferase SCO1865 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 21220421 Common - transketolase SCO1935 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 21219658 Common - ABC transporter ATP-binding protein SCO1144 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21218960 Common - DNA-binding protein SCO0418 18 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 21220739 Common - membrane protein SCO2270 5 COG3889 COG3889, Predicted solute binding protein General function prediction only 21222414 Nonpathogen - integral membrane protein SCO4011 1 None None None 21221358 Common - hypothetical protein SCO2911 43 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 21221674 Common - putaive isomerase SCO3241 33 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 21224715 Common - gamma-glutamyltranspeptidase (putative secreted protein) SCO6407 147 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 21218749 Common - DNA-binding regulator SCO0193 16 COG0789 SoxR, Predicted transcriptional regulators Transcription 21223297 Common - hypothetical protein SCO4923 168 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 21222589 Nonpathogen - ATP/GTP-binding membrane protein SCO4193 1 None None None 21219087 Common - response regulator SCO0552 204 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21224172 Common - two-component transcriptional regulator SCO5828 219 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 21225978 Nonpathogen - tetR-family transcriptional regulator SCO7719 2 COG1309 AcrR, Transcriptional regulator Transcription 21219450 Nonpathogen - secreted proline-rich protein SCO0931 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21218719 Common - hypothetical protein SCO0162 19 None None None 21221749 Common hemC porphobilinogen deaminase SCO3318 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 21220985 Nonpathogen - hypothetical protein SCO2524 2 None None None 21225046 Common - nucleotide sugar-1-phosphate transferase SCO6753 63 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 32141230 Common - phosphate transport system regulator SCO4228 189 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 21224429 Common - phosphoadenosine phosphosulfate reductase SCO6100 165 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 21222058 Common - hypothetical protein SCO3643 8 None None None 21220863 Common - hypothetical protein SCO2396 109 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 21219936 Nonpathogen - hypothetical protein SCO1433 3 None None None 21224874 Common - secreted protein SCO6573 15 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 21221189 Common gltA type II citrate synthase SCO2736 194 COG0372 GltA, Citrate synthase Energy production and conversion 21223929 Common - formamidopyrimidine-DNA glycosylase SCO5573 179 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 21223182 Common - hypothetical protein SCO4804 23 None None None 21221346 Common - GroES-family molecular chaperone SCO2899 72 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 21223338 Common - transcription elongation factor SCO4965 203 COG0782 GreA, Transcription elongation factor Transcription 21220781 Common - hypothetical protein SCO2313 43 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 21220798 Common - isochorismatase SCO2330 66 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 21223037 Nonpathogen - integral membrane protein SCO4656 1 None None None 21221510 Nonpathogen - integral membrane protein SCO3069 2 None None None 21223728 Common - ATP synthase C chain SCO5368 11 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 21222645 Nonpathogen - hypothetical protein SCO4250 1 None None None 21224851 Common - hypothetical protein SCO6549 6 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 21223426 Common - secreted protein SCO5053 78 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 21224110 Nonpathogen - hypothetical protein SCO5764 1 None None None 21219671 Common - hypothetical protein SCO1158 9 None None None 32141169 Common - secreted beta-galactosidase SCO2430 24 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 21220287 Common - secreted protein SCO1796 216 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 32141227 Common - lipoprotein SCO4134 45 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 21226026 Common - hypothetical protein SCO7773 3 None None None 21218722 Common - hypothetical protein SCO0165 40 COG3439 COG3439, Uncharacterized conserved protein Function unknown 21219561 Nonpathogen - metal associated protein SCO1045 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 21224940 Common - hypothetical protein SCO6643 10 COG0456 RimI, Acetyltransferases General function prediction only 21220501 Common - chorismate mutase SCO2019 58 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 21220551 Common - Na+/H+ antiporter SCO2071 86 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 21224454 Common - carboxylesterase SCO6127 83 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 21221116 Common - sugar transport membrane protein SCO2660 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21220732 Nonpathogen - hypothetical protein SCO2263 2 None None None 21225311 Common - hypothetical protein SCO7026 29 None None None 21223997 Common - solute binding lipoprotein SCO5646 71 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 21219200 Common - glycerol-3-phosphate dehydrogenase SCO0670 132 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 21219618 Common - hydrolase SCO1103 19 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 21222750 Common - ABC transport system ATP-binding protein SCO4359 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21225739 Common - phenylacetic acid degradation protein PaaA SCO7471 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 21222882 Nonpathogen - hypothetical protein SCO4497 1 None None None 21223030 Common rplK 50S ribosomal protein L11 SCO4648 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 21220042 Common - hypothetical protein SCO1542 26 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21224231 Nonpathogen - hypothetical protein SCO5889 3 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222392 Nonpathogen - hypothetical protein SCO3988 1 None None None 21220961 Nonpathogen - hypothetical protein SCO2500 1 None None None 21221319 Nonpathogen - hypothetical protein SCO2870 1 None None None 32141213 Common dnaK molecular chaperone DnaK SCO3671 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 21219092 Nonpathogen - hypothetical protein SCO0558 1 None None None 21224557 Common - hypothetical protein SCO6235 5 None None None 21219336 Common - hypothetical protein SCO0815 162 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 21219817 Common - cation efflux system protein SCO1310 99 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 21224679 Common - ABC transporter ATP-binding protein SCO6367 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21224972 Nonpathogen - hypothetical protein SCO6676 1 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 21224542 Common - hypothetical protein SCO6220 69 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 21219859 Nonpathogen - transcriptional regulator SCO1353 5 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21223947 Common - hypothetical protein SCO5592 51 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 21224146 Common - hypothetical protein SCO5801 54 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21221837 Common - hypothetical protein SCO3410 25 COG2966 COG2966, Uncharacterized conserved protein Function unknown 21222628 Common - 4-diphodphocytidyl-2C-methyl-D-erythriol synthase SCO4233 182 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 21223133 Common - transcriptional regulator SCO4754 126 COG1609 PurR, Transcriptional regulators Transcription 21221933 Nonpathogen - integral membrane protein SCO3512 1 None None None 21221859 Common - hypothetical protein SCO3432 6 None None None 21220395 Common - large secreted protein SCO1908 42 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 21223984 Common - ATP /GTP-binding protein SCO5629 39 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 21221732 Nonpathogen - secreted serine-rich protein SCO3300 1 None None None 21225199 Nonpathogen - hypothetical protein SCO6909 1 None None None 21220773 Common - dehydrogenase SCO2304 31 COG2030 MaoC, Acyl dehydratase Lipid metabolism 21223270 Common - transport integral membrane protein SCO4896 90 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21224916 Nonpathogen - hypothetical protein SCO6618 2 None None None 21220460 Common - putative oxidoreductase SCO1977 190 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 21225835 Common - hypothetical protein SCO7571 126 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21224573 Nonpathogen - hypothetical protein SCO6252 1 None None None 21218916 Common - secreted protein SCO0372 7 None None None 21222028 Nonpathogen - hypothetical protein SCO3612 1 None None None 21224399 Common - large secreted protein SCO6069 43 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21224524 Nonpathogen - hypothetical protein SCO6200 1 None None None 21219467 Common - hypothetical protein SCO0949 8 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 21224156 Common rnhB ribonuclease HII SCO5812 229 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 21220036 Common - hypothetical protein SCO1536 7 None None None 21224280 Common - hypothetical protein SCO5942 9 COG1309 AcrR, Transcriptional regulator Transcription 21225714 Common - hypothetical protein SCO7445 52 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 21223000 Nonpathogen - ATP-binding protein SCO4617 11 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 21219439 Common - acyltransferase SCO0920 71 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 21224372 Common - lipoprotein SCO6040 31 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 21223407 Nonpathogen - integral membrane protein SCO5034 3 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 21222127 Common - transposase SCO3714 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219763 Common - G/U mismatch-specific DNA glycosylase SCO1255 29 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 21219113 Common - glycerone kinase SCO0580 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 21220878 Nonpathogen - hypothetical protein SCO2411 2 None None None 21225065 Common - hypothetical protein SCO6772 51 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 21225781 Nonpathogen - hypothetical protein SCO7515 2 None None None 21220381 Common - hypothetical alanine-rich protein SCO1894 9 None None None 21224984 Nonpathogen - hypothetical protein SCO6689 2 None None None 21222393 Common - ribonuclease inhibitor SCO3989 5 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 21220226 Nonpathogen - hypothetical protein SCO1732 1 None None None 21223826 Common - L-serine dehydratase SCO5469 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 21226080 Nonpathogen - hypothetical protein SCO7831 1 None None None 21220101 Common - hypothetical protein SCO1604 13 None None None 21225001 Common ligC ATP-dependent DNA ligase SCO6707 46 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 21222345 Nonpathogen - transmembrane protein SCO3940 1 None None None 21223333 Nonpathogen - sigma factor SCO4960 1 None None None 21220313 Common - secreted subtilisin-like protease SCO1824 124 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21222433 Common - hypothetical protein SCO4030 116 COG2353 COG2353, Uncharacterized conserved protein Function unknown 21223591 Common - cytochrome P450 SCO5223 77 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21223841 Nonpathogen - small hydrophobic membrane protein SCO5484 1 None None None 21223867 Common - membrane associated phophodiesterase SCO5511 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 21219186 Common - gas vesicle synthesis protein SCO0656 4 None None None 21220840 Nonpathogen - small hydrophobic protein SCO2372 1 None None None 32141160 Common lipB lipoyltransferase SCO2193 168 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 32141139 Common - hypothetical protein SCO1319 3 None None None 21224949 Nonpathogen - hypothetical protein SCO6653 10 COG0392 COG0392, Predicted integral membrane protein Function unknown 21225345 Common - methylase SCO7062 196 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 21221578 Common - hypothetical protein SCO3140 7 None None None 21221906 Common - sugar-permease SCO3482 160 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21223582 Common - hypothetical protein SCO5214 104 COG2135 COG2135, Uncharacterized conserved protein Function unknown 21221284 Common - hypothetical protein SCO2834 35 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 21223111 Nonpathogen - hypothetical protein SCO4732 1 None None None 21222245 Common - rRNA methylase SCO3836 58 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 21222759 Common - lipase (secreted protein) SCO4368 11 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 21225610 Common - alpha-amylase SCO7335 76 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 21222657 Common - transcriptional regulatory protein SCO4263 16 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21224647 Common - transcriptional regulator SCO6334 75 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 21225241 Common - putative monovalent cation/H+ antiporter subunit A SCO6954 206 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 32141314 Common - phosphonopyruvate decarboxylase (fragment) SCO6824 36 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 21223275 Common - adenosine deaminase SCO4901 102 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 21220172 Common - hypothetical protein SCO1676 191 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 21221051 Nonpathogen - hypothetical protein SCO2593 1 None None None 21225024 Common - racemase SCO6730 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 21226046 Common - TetR-family transcriptional regulator SCO7794 46 COG1309 AcrR, Transcriptional regulator Transcription 21220269 Common - hypothetical protein SCO1777 71 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 21219412 Common - integral membrane protein SCO0892 93 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 21225318 Common - regulatory protein SCO7033 35 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 21221563 Common - peptidyl-tRNA hydrolase SCO3125 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 21224721 Common - hypothetical protein SCO6414 198 COG0388 COG0388, Predicted amidohydrolase General function prediction only 21224420 Common - integral membrane protein SCO6091 34 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21225880 Common - transcriptional regulator SCO7618 107 COG1414 IclR, Transcriptional regulator Transcription 21219559 Common - transcriptional regulatory protein SCO1043 111 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 21224505 Common - transferase SCO6181 26 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 21222668 Common - histidine autokinase SCO4275 85 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21224262 Common - ABC transporter ATP-binding protein SCO5923 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 21225862 Common - transcriptional regulator SCO7599 118 COG1737 RpiR, Transcriptional regulators Transcription 21222467 Nonpathogen - hypothetical protein 2SCD6030c SCO4064 1 None None None 21224065 Nonpathogen - secreted protein SCO5718 1 COG1520 COG1520, FOG: WD40-like repeat Function unknown 21224191 Common - transcriptional regulator SCO5847 105 COG2188 PhnF, Transcriptional regulators Transcription 21220436 Common - hypothetical protein SCO1951 87 COG0391 COG0391, Uncharacterized conserved protein Function unknown 21224670 Common - hypothetical protein SCO6357 103 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 21225971 Common - two component system response regulator SCO7712 187 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21221947 Common - hypothetical protein SCO3526 18 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 21219771 Common - ECF-sigma factor SCO1263 49 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220649 Common - nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase SCO2175 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 21219611 Nonpathogen - hypothetical protein S2SCG412 SCO1096 1 None None None 21221254 Common - hypothetical protein SCO2803 33 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 21224408 Common - hypothetical protein SCO6079 36 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 21220602 Nonpathogen - hypothetical protein SCO2124 1 None None None 21225983 Common - hypothetical protein SCO7724 2 None None None 21222868 Common - lysR-family transcriptional regulator SCO4482 155 COG0583 LysR, Transcriptional regulator Transcription 21218845 Common - transcriptional regulator SCO0296 38 COG1309 AcrR, Transcriptional regulator Transcription 21219919 Common - membrane protein SCO1416 4 None None None 21220131 Nonpathogen - hypothetical protein SCO1635 1 None None None 21222576 Common - hypothetical protein SCO4179 16 None None None 21218947 Common - hypothetical protein SCO0405 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 32141149 Common - hypothetical protein SCO1618 78 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 21222063 Common - transmembrane efflux protein SCO3648 195 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21225887 Common - monooxygenase SCO7625 50 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21219588 Common - hydrogenase SCO1073 93 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21220371 Common - hypothetical protein SCO1884 4 None None None 21225451 Common - lyase SCO7171 17 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21223870 Common - ketol-acid reductoisomerase SCO5514 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 21222744 Common - hypothetical protein SCO4353 111 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21218632 Nonpathogen - hypothetical protein SCO0057 1 None None None 21223112 Nonpathogen - integral membrane protein SCO4733 1 None None None 21221722 Nonpathogen - hypothetical protein SCO3290 2 COG4271 COG4271, Predicted nucleotide-binding protein containing TIR -like domain Transcription 21219990 Common - DNA-binding protein SCO1489 7 COG1395 COG1395, Predicted transcriptional regulator Transcription 21222837 Common - hydrolase SCO4449 24 COG4257 Vgb, Streptogramin lyase Defense mechanisms 21225515 Common - hypothetical protein SCO7238 14 None None None 21219068 Common - sugar transporter membrane protein SCO0533 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21225255 Common - probable long-chain-fatty-acid-CoA ligase SCO6968 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21221128 Nonpathogen - hypothetical protein SCO2672 1 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 21224640 Common - integral membrane protein SCO6326 7 None None None 21218584 Common - hypothetical protein SCO0002 23 COG4889 COG4889, Predicted helicase General function prediction only 32141170 Common - sugar kinase (fragment) SCO2462 149 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 21222640 Common - hypothetical protein SCO4245 37 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 21219031 Common - ABC-transporter transmembrane protein SCO0493 245 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21224126 Common - secreted protein SCO5781 10 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 21220594 Common - secreted protein SCO2116 55 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 21223838 Common - integral membrane protein SCO5481 133 COG2860 COG2860, Predicted membrane protein Function unknown 21222094 Common - hypothetical protein SCO3681 3 None None None 32141135 Common - reductase SCO1201 179 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 21219405 Common - thioredoxin SCO0885 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 21222038 Common - hypothetical protein SCO3622 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 21220650 Common - integral membrane protein SCO2176 6 None None None 21222974 Common - hypothetical protein SCO4591 30 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21225176 Common - DNA methylase SCO6885 98 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 21221303 Common - hypothetical protein SCO2853 117 COG1733 COG1733, Predicted transcriptional regulators Transcription 21222766 Nonpathogen - hypothetical protein SCO4376 1 None None None 21223977 Common - transcriptional regulator SCO5622 3 None None None 21224020 Common - polyamine ABC-transporter integral memb rane protein SCO5670 138 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 21224906 Common - secreted protein SCO6608 26 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 21226031 Common - transcriptional regulator SCO7778 103 COG1414 IclR, Transcriptional regulator Transcription 32141187 Common - tetR-family transcriptional regulator (fragment) SCO2994 36 COG1309 AcrR, Transcriptional regulator Transcription 21220250 Nonpathogen - hypothetical protein 2SCI3410 SCO1757 1 None None None 21222485 Nonpathogen - hypothetical protein SCO4083 1 None None None 21224021 Common - oxidoreductase SCO5671 96 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 21224102 Common - hypothetical protein SCO5756 59 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 21224780 Nonpathogen - hypothetical protein SCO6476 1 None None None 21219071 Nonpathogen - hypothetical protein SCO0536 1 None None None 21218991 Common - integral membrane protein SCO0450 23 COG3447 COG3447, Predicted integral membrane sensor domain Signal transduction mechanisms 21219127 Common - methyltransferase SCO0594 56 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221071 Common - hypothetical protein SCO2613 11 None None None 21222017 Common - hypothetical protein SCO3601 25 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 21225306 Common - secreted protein SCO7021 109 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 21218878 Common - dioxygenase (secreted protein) SCO0333 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21218789 Common - DNA-binding protein SCO0236 41 COG1396 HipB, Predicted transcriptional regulators Transcription 21219928 Common - AsnC-family transcriptional regulatory protein SCO1425 162 COG1522 Lrp, Transcriptional regulators Transcription 21224772 Common - phosphatidylserine decarboxylase SCO6468 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 21222312 Nonpathogen - hypothetical protein SCO3905 1 None None None 21220821 Nonpathogen - hypothetical protein SCO2353 1 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21224007 Common - transcriptional regulatory protein SCO5656 137 COG1522 Lrp, Transcriptional regulators Transcription 21224206 Common - two-component sensor (kinase) SCO5863 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21222113 Common - heavy metal reductase SCO3700 128 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 21225747 Nonpathogen - integral membrane protein SCO7479 1 None None None 21225793 Common - hypothetical protein SCO7528 52 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 21219445 Common - hypothetical protein SCO0926 13 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21221644 Common - transcriptional regulator SCO3209 55 COG1414 IclR, Transcriptional regulator Transcription 21219538 Common - hypothetical protein SCO1022 51 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 21222154 Common - glycosyltransferase SCO3742 61 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21225936 Common - ferredoxin SCO7676 11 COG1141 Fer, Ferredoxin Energy production and conversion 21224053 Common nusA transcription elongation factor NusA SCO5704 220 COG0195 NusA, Transcription elongation factor Transcription 21222998 Common - integrase SCO4615 20 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 21222136 Nonpathogen - hypothetical protein SCO3724 1 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21222025 Common - hypothetical protein SCO3609 15 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 21223007 Common - hypothetical protein SCO4624 4 None None None 21218744 Common - phytoene synthase SCO0187 109 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 21221154 Nonpathogen - small membrane protein SCO2699 1 None None None 21220690 Nonpathogen - lipoprotein SCO2218 1 None None None 21219547 Common - ABC transport system integral membrane protein SCO1031 34 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 21222903 Nonpathogen - integral membrane protein SCO4518 1 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 21226008 Common - regulatory protein SCO7751 7 COG1846 MarR, Transcriptional regulators Transcription 21225669 Common - iron-hydroxamate transporter permease subunit SCO7398 184 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 21223905 Common - transcriptional regulator SCO5550 12 COG0789 SoxR, Predicted transcriptional regulators Transcription 21225716 Common - acetyltranferase SCO7447 71 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21220858 Common - hypothetical protein SCO2391 17 None None None 21224650 Common - transposase SCO6337 120 None None None 21225958 Common - merR-family transcriptional regulator SCO7698 104 COG0789 SoxR, Predicted transcriptional regulators Transcription 21219627 Common - hypothetical protein SCO1113 38 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 21224624 Common - hypothetical protein SCO6306 88 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21226001 Common - MarR-family transcriptional regulator SCO7742 46 COG1846 MarR, Transcriptional regulators Transcription 21225190 Common - hypothetical protein SCO6900 29 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 21221130 Common - ABC transporter ATP-binding protein SCO2674 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21221330 Common - hypothetical protein SCO2881 9 COG1414 IclR, Transcriptional regulator Transcription 21224012 Common - hypothetical protein SCO5661 137 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 21223653 Common - MarR-family transcriptional regulator SCO5287 24 COG1846 MarR, Transcriptional regulators Transcription 21224468 Nonpathogen - hypothetical protein SCO6142 1 None None None 21223912 Nonpathogen - hypothetical protein SCO5557 2 None None None 32141110 Nonpathogen - integral membrane protein SCO0402 1 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21219902 Common - hypothetical protein SCO1398 148 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 21221969 Common - helicase SCO3550 154 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 21219078 Common - peptidase SCO0543 185 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21219550 Common - tetR-family regulatory protein SCO1034 108 COG1309 AcrR, Transcriptional regulator Transcription 21223318 Common - dehydrogenase SCO4945 202 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 21221404 Common - nitrate extrusion protein SCO2959 78 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 21218977 Common - aminotransferase SCO0435 206 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 21224588 Common - hypothetical protein SCO6267 74 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 32141203 Common - DNA polymerase I SCO3434 97 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 21225517 Common - serine/threonine-protein kinase SCO7240 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21220052 Common - uroporphyrin-III methyltransferase SCO1553 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 21223765 Common - transcriptional regulator SCO5405 57 COG1846 MarR, Transcriptional regulators Transcription 21225584 Common - membrane transport protein SCO7308 72 COG1279 COG1279, Lysine efflux permease General function prediction only 21221864 Common - hypothetical protein SCO3438 10 COG3439 COG3439, Uncharacterized conserved protein Function unknown 21222857 Common - phosphoglycerate mutase SCO4470 41 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 21219620 Nonpathogen - secreted protein SCO1105 6 COG5276 COG5276, Uncharacterized conserved protein Function unknown 21225112 Common - 3-phosphoshikimate 1-carboxyvinyltransferase SCO6819 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 21219381 Common - probable cation-transporting ATPase SCO0860 228 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 21219890 Common - integral membrane protein SCO1386 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 21220334 Common - low-affinity phosphate transport protein SCO1845 165 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 21220023 Common - pyridoxine biosynthesis protein SCO1523 88 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 21225908 Nonpathogen - calcium binding protein SCO7647 2 None None None 21219810 Nonpathogen - hypothetical protein SCO1303 3 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21221634 Common - transmembrane efflux protein SCO3199 214 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21220698 Common - bi-functional protein (secreted alpha-amylase/dextrinase) SCO2226 167 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 21224461 Common - regulatory protein SCO6134 173 COG0714 COG0714, MoxR-like ATPases General function prediction only 21225525 Common - hypothetical protein SCO7248 6 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 21218780 Nonpathogen - hypothetical protein SCO0227 1 None None None 21223541 Common - hydrolase SCO5172 50 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21223950 Common rplS 50S ribosomal protein L19 SCO5595 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 21221161 Common - transferase SCO2706 201 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 21223167 Nonpathogen - ntegral membrane protein SCO4788 1 None None None 21224660 Common - beta-galactosidase SCO6347 24 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 21225184 Nonpathogen - hypothetical protein SCO6893 1 None None None 21221811 Common - L-aspartate oxidase SCO3382 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 21225330 Common uppP undecaprenyl pyrophosphate phosphatase SCO7047 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 32141309 Common - hypothetical protein SCO6627 40 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 21221958 Nonpathogen - hypothetical protein SCO3538 1 None None None 21220259 Common - DNA hydrolase SCO1767 89 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 21220123 Common - ATP-GTP binding protein SCO1627 32 COG2229 COG2229, Predicted GTPase General function prediction only 21223629 Common - dehydrogenase SCO5262 171 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21225798 Common - two-component system response regulator SCO7533 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21219596 Common - electron transfer flavoprotein, alpha subunit SCO1081 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 21220061 Common - integral membrane protein SCO1562 12 None None None 32141177 Common - secreted sugar-binding protein SCO2658 112 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21225157 Nonpathogen - hypothetical protein SCO6866 1 None None None 21225509 Nonpathogen - secreted protein SCO7232 2 None None None 21223706 Common - hypothetical protein SCO5345 128 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 21222678 Common - sugar kinase SCO4285 160 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21223431 Common - polyphosphate glucokinase SCO5059 111 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21221784 Common - adenine glycosylase SCO3355 202 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 21223266 Nonpathogen - regulatory protein SCO4892 3 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 21221880 Common - ABC-transporter transport protein SCO3455 11 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 21224806 Nonpathogen - hypothetical protein SCO6503 1 COG5406 COG5406, Nucleosome binding factor SPN, SPT16 subunit Transcription / DNA replication, recombination, and repair / Chromatin structure and dynamics 21222010 Common - D-lactate dehydrogenase SCO3594 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 21220155 Common - glycerol uptake facilitator protein SCO1659 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 21223815 Common - lipoprotein SCO5457 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 21221818 Common - two component sensor kinase SCO3390 73 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21220095 Common rplT 50S ribosomal protein L20 SCO1598 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 21221793 Nonpathogen - hypothetical protein SCO3364 1 None None None 21224245 Common - probable transcriptional regulator SCO5906 2 COG1309 AcrR, Transcriptional regulator Transcription 21226040 Nonpathogen - hypothetical protein SCO7789 1 None None None 21224225 Nonpathogen - hypothetical protein SCO5883 7 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 32141192 Common - nucleotidyltransferase SCO3122 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 21221425 Common - glycosyl transferase SCO2981 212 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 21221899 Common - isomerase SCO3475 105 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21218951 Nonpathogen - spore-associated protein precursor SCO0409 2 None None None 21220558 Common - hypothetical protein SCO2078 18 None None None 21221053 Common obgE GTPase ObgE SCO2595 249 COG0536 Obg, Predicted GTPase General function prediction only 21224109 Common - membrane protein SC4H802 SCO5763 49 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 21223572 Common - hypothetical protein 2SC3B627c SCO5203 9 None None None 21222190 Common - nucleoside hydrolase SCO3779 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 21218733 Common - hypothetical protein SCO0176 2 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 21219965 Common - transcriptional regulator SCO1463 65 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 21222960 Common - helicase SCO4577 213 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 21219027 Common - hypothetical protein SCO0489 37 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 21225767 Common - allantoin permease SCO7500 52 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 21218666 Nonpathogen - hypothetical protein SCO0102 1 None None None 21222199 Nonpathogen - hypothetical protein SCO3788 10 None None None 21219125 Nonpathogen - hypothetical protein SCO0592 1 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 21219920 Common - GntR-family regulatory protein SCO1417 213 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 21220525 Common hisI phosphoribosyl-AMP cyclohydrolase SCO2044 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 21223126 Common - ATP/GTP binding protein SCO4747 17 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 21222280 Common - integral membrane protein SCO3872 17 None None None 21225373 Nonpathogen - hypothetical protein SCO7091 1 None None None 21222334 Common - thiamine biosynthesis protein ThiC SCO3928 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 21220274 Common - hypothetical protein SCO1782 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 21223357 Common - aminotransferase AlaT SCO4984 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 21219350 Common - serine protease SCO0829 17 None None None 32141334 Common - hypothetical protein SCO7509 20 COG2170 COG2170, Uncharacterized conserved protein Function unknown 21222373 Nonpathogen - ATP/GTP-binding protein SCO3969 1 None None None 21219809 Common - hypothetical protein SCO1302 137 COG1739 COG1739, Uncharacterized conserved protein Function unknown 21221207 Common - acetyltransferase SCO2755 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21222691 Common - carboxylesterase SCO4298 63 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 21223832 Nonpathogen - hypothetical protein SCO5475 1 None None None 21224198 Common - thiosulfate sulfurtransferase SCO5854 139 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 21221081 Common - integral membrane protein SCO2624 42 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21223957 Common - hypothetical protein SCO5602 111 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 21220366 Common - secreted protein SCO1878 24 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 21223630 Common - hypothetical protein SCO5263 23 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 21224013 Common - adenosine deaminase SCO5662 114 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 21225104 Nonpathogen - secreted protein SCO6811 16 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 21218972 Common - tetR family transcriptional regulator SCO0430 30 COG1309 AcrR, Transcriptional regulator Transcription 21220364 Common - RNA polymerase sigma factor SCO1876 11 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21224210 Common - hypothetical protein SCO5867 33 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 21223534 Common - hydrolase SCO5165 26 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21224795 Nonpathogen - hypothetical protein SCO6491 3 None None None 21224922 Nonpathogen - hypothetical protein SCO6624 1 None None None 21222716 Nonpathogen - integral membrane protein SCO4324 1 None None None 21223637 Common - hypothetical protein SCO5270 90 COG0714 COG0714, MoxR-like ATPases General function prediction only 21220785 Common - methyltransferase SCO2317 162 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21225724 Common - isochorismatase SCO7455 88 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 21220072 Nonpathogen - hypothetical protein SCO1574 6 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 21223188 Nonpathogen - hypothetical protein SCO4810 3 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225366 Common - hypothetical protein SCO7084 2 None None None 21221697 Common - gntR-family regulator SCO3264 112 COG2188 PhnF, Transcriptional regulators Transcription 21221915 Common - acetyl transferase SCO3493 99 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 21224937 Common - ATP-dependent helicase SCO6640 234 COG1201 Lhr, Lhr-like helicases General function prediction only 21221657 Nonpathogen - secreted protein SCO3222 3 None None None 21219802 Common - AsnC-family transcriptional regulatory protein SCO1295 132 COG1522 Lrp, Transcriptional regulators Transcription 21219723 Common - hypothetical protein SCO1213 61 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 21219507 Nonpathogen - integral membrane protein SCO0990 3 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 21219107 Common - hypothetical protein SCO0573 14 None None None 21224445 Common - AraC family transcriptional regulator SCO6118 112 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21219144 Nonpathogen - hypothetical protein SCO0611 1 COG0730 COG0730, Predicted permeases General function prediction only 21221362 Common - hypothetical protein SCO2915 15 None None None 21222461 Common - hypothetical protein 2SCD6024 SCO4058 6 COG3832 COG3832, Uncharacterized conserved protein Function unknown 21219870 Nonpathogen - hypothetical protein SCO1365 1 None None None 21224779 Common - oxidoreductase SCO6475 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 21224000 Common - hypothetical protein SCO5649 9 None None None 21219609 Common - tetR-family regulatory protein SCO1094 93 COG1309 AcrR, Transcriptional regulator Transcription 21226014 Common - oxidoreductase fragment SCO7760 13 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21224742 Common - tRNA synthetase SCO6436 232 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21221588 Common - hypothetical protein SCO3151 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 21222298 Nonpathogen - hypothetical protein SCO3891 1 None None None 21224311 Common - integral membrane ion exchanger SCO5974 51 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 21219056 Common - TetR family transcriptional regulator SCO0521 20 COG1309 AcrR, Transcriptional regulator Transcription 21221759 Common - hypothetical protein SCO3328 24 None None None 21225760 Common - hypothetical protein SCO7492 22 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 21224863 Common - respiratory chain oxidoreductase SCO6561 186 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 21222292 Common gidB glucose-inhibited division protein B SCO3885 195 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 21220428 Common - electron transport protein SCO1943 19 None None None 21219154 Common - tetR-family transcriptional regulator SCO0622 3 COG1309 AcrR, Transcriptional regulator Transcription 21222205 Common - glycosyl transferase SCO3794 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21225825 Common - esterase SCO7561 110 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 21219459 Common - marR-family regulatory protein SCO0940 22 COG1846 MarR, Transcriptional regulators Transcription 21225948 Common - hypothetical protein SCO7688 4 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21221820 Common - NADH dehydrogenase subunit NuoD2 SCO3392 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 21222833 Nonpathogen - transcriptional regulator SCO4445 3 COG0640 ArsR, Predicted transcriptional regulators Transcription 21219136 Common - amino transferase SCO0603 216 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 21225801 Common - integral membrane protein SCO7536 39 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 21219430 Common - hypothetical protein SCO0910 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 21222282 Common gyrB DNA gyrase subunit B SCO3874 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 21224645 Common - hypothetical protein SCO6331 25 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 21225128 Common - ArsR-family transcriptional regulator SCO6836 106 COG0640 ArsR, Predicted transcriptional regulators Transcription 21219388 Nonpathogen - integral-membrane protein SCO0867 1 None None None 21223871 Common - probable D-3-phosphoglycerate dehydrogenase SCO5515 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 21223140 Common groES co-chaperonin GroES SCO4761 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 21223208 Common - glycine betaine ABC transport system integral membrane protein SCO4831 160 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 21226049 Nonpathogen - transposase fragment SCO7797 1 None None None 21219747 Common - ATP-dependent Clp protease SCO1238 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 21221760 Common - hypothetical protein SCO3329 3 None None None 21221813 Common - L-allo-threonine aldolase SCO3385 72 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 21223515 Common - methyltransferase SCO5146 58 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 21225187 Nonpathogen - hypothetical protein SCO6897 1 None None None 21221370 Common - hypothetical protein SCO2923 3 COG1714 COG1714, Predicted membrane protein/domain Function unknown 21218969 Common - hydrolase SCO0427 40 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21224831 Common - ATP/GTP binding protein SCO6529 48 COG0714 COG0714, MoxR-like ATPases General function prediction only 21225137 Common - hypothetical protein SCO6845 7 None None None 21219345 Common - ABC transporter ATP-binding protein SCO0824 242 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21221131 Nonpathogen - hypothetical protein SCO2675 1 None None None 21222876 Common - decarboxylase SCD6910 SCO4490 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 21223411 Common - integral membrane protein SCO5038 37 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 21225422 Common - hypothetical protein SCO7142 141 COG1733 COG1733, Predicted transcriptional regulators Transcription 21219867 Nonpathogen - integral membrane protein SCO1362 1 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 21222177 Common - hypothetical protein SCO3766 20 COG4326 Spo0M, Sporulation control protein General function prediction only 21225419 Nonpathogen - hypothetical protein SCO7138 1 None None None 21224803 Common - gas vesicle synthesis-like protein SCO6500 22 None None None 21225412 Common - hypothetical protein SCO7130 29 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 21224274 Nonpathogen - hypothetical protein SCO5936 1 None None None 21223673 Nonpathogen - hypothetical protein SCO5310 1 None None None 21223965 Nonpathogen - hypothetical protein SCO5610 1 None None None 21224302 Nonpathogen - hypothetical protein SCO5964 1 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 21225429 Nonpathogen - lyase SCO7149 3 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21220543 Common - hypothetical protein SCO2062 7 COG1432 COG1432, Uncharacterized conserved protein Function unknown 21224911 Common - hypothetical protein SCO6613 107 COG1733 COG1733, Predicted transcriptional regulators Transcription 21221701 Nonpathogen - secreted protein SCO3268 1 None None None 21219292 Common - lipoprotein SCO0768 7 None None None 21224213 Common - ABC transporter ATP-binding protein SCO5870 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21221980 Common - secreted protein SCO3561 11 None None None 21224064 Common - hypothetical protein SCO5717 14 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 21218596 Nonpathogen - hypothetical protein SCO0014 1 None None None 21221114 Common - ROK-family transcriptional regulatory protein SCO2657 94 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21221714 Common - hypothetical protein SCO3281 35 None None None 21224474 Common - hypothetical protein SCO6148 9 None None None 32141175 Common - glycosyltransferase SCO2590 115 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 21220754 Common - oxidoreductase SCO2285 160 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21218752 Nonpathogen - hypothetical protein SCO0196 1 None None None 21219375 Common - hypothetical protein SCO0854 5 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 21224121 Common - glutamate permease SCO5775 170 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 21221651 Common - integral membrane ATPase SCO3216 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 21223890 Common - carboxyl transferase SCO5535 217 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 21222634 Nonpathogen - small membrane protein SCO4239 1 None None None 21224005 Common - ABC transporter ATP-binding protein SCO5654 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21222962 Common - integral membrane protein SCO4579 12 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 21222083 Common - molecular chaperone SCO3669 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 21222920 Nonpathogen - hypothetical protein SCO4536 2 None None None 21219109 Common - peptidase E SCO0575 32 COG3340 PepE, Peptidase E Amino acid transport and metabolism 21219896 Nonpathogen - hypothetical protein SCO1392 1 None None None 21220490 Common - branched chain amino acid binding protein SCO2008 135 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 21222478 Common - LSR2-like protein SCO4076 17 None None None 21223546 Common - hypothetical protein 2SC3B601 SCO5177 6 None None None 21219560 Common - secreted protein SCO1044 14 None None None 21223814 Common - glycosyl hydrolase (secreted protein) SCO5456 149 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 21225967 Common - hypothetical protein SCO7708 19 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 21221646 Common - indoleglycerol phosphate synthase SCO3211 217 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 21222655 Common - response regulator SCO4261 82 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 21220883 Common - secreted protein SCO2417 18 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 21222131 Common - potassium-transporting ATPase subunit A SCO3718 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 21222992 Common - heat shock protein HtpX SCO4609 188 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 21225218 Nonpathogen - hypothetical protein SCO6931 1 None None None 21219567 Common - integral membrane protein SCO1051 9 None None None 21219509 Common - cysteine synthase SCO0992 139 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 21223017 Common rpmG 50S ribosomal protein L33 SCO4635 85 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 21219707 Common - secreted protein SCO1196 7 None None None 21221382 Common - transcriptional regulator SCO2935 50 COG1414 IclR, Transcriptional regulator Transcription 21222402 Nonpathogen - lipoprotein SCO3999 1 None None None 21220326 Nonpathogen - hypothetical protein SCO1837 1 None None None 21222465 Common - transposase SCO4062 4 None None None 21218833 Nonpathogen - hypothetical protein SCO0283 1 None None None 21221240 Common - glucosamine-fructose-6-phosphate aminotransferase SCO2789 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 21219255 Common - hypothetical protein SCO0730 12 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 21222602 Common - AraC-family transcriptional regulator SCO4206 40 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21218644 Common - hypothetical protein SCO0069 10 None None None 21220579 Nonpathogen - hypothetical protein SCO2099 1 None None None 21218705 Nonpathogen - transmembrane transport protein SCO0147 3 None None None 21222625 Common - response regulator SCO4230 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21224351 Nonpathogen - hypothetical protein SCO6019 1 None None None 21221005 Common - adenosine deaminase SCO2546 100 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 21223032 Nonpathogen - lipoprotein SCO4650 1 None None None 21225460 Common - branched amino acid transport system ATP-binding protein SCO7181 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 21225260 Common - hypothetical protein SCO6973 78 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 21224884 Common - TPP-requiring enzyme SCO6584 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 21219843 Common - oxidoreductase SCO1337 80 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 21221871 Common - dehalogenase SCO3446 60 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 21225778 Common - AraC-family transcriptional regulator SCO7512 122 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 21218853 Common - hypothetical protein SCO0304 31 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21223519 Common - sec-independent translocase SCO5150 9 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 21222356 Common - hypothetical protein SCO3951 21 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 21224669 Common - integral membrane protein SCO6356 3 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21221663 Common - 4-hydroxyphenylpyruvic acid dioxygenase SCO3229 77 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 21221606 Nonpathogen - hypothetical protein SCO3169 1 None None None 21225264 Common - carbohydrate kinase SCO6978 98 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 21218761 Nonpathogen - hypothetical protein SCO0207 1 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 21220113 Common - transcriptional regulator SCO1616 182 COG0583 LysR, Transcriptional regulator Transcription 21223800 Common - hypothetical protein SCO5441 56 COG3281 Ble, Uncharacterized protein, probably involved in trehalose biosynthesis Carbohydrate transport and metabolism 21225085 Common - TetR-family transcriptional regulator SCO6792 37 COG1309 AcrR, Transcriptional regulator Transcription 21223463 Common - actinorhodin polyketide dimerase SCO5092 125 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 21226065 Common - membrane protein SCO7816 4 COG0730 COG0730, Predicted permeases General function prediction only 21221159 Nonpathogen - secreted protein SCO2704 1 None None None 21222583 Common - hypothetical protein SCO4186 17 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 21219160 Common - secreted protein SCO0628 29 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 21224097 Common - hypothetical protein SCO5751 45 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 21225990 Common - hypothetical protein SCO7731 16 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 21218628 Common - hypothetical protein SCO0049 6 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 21223780 Common - cholesterol esterase SCO5420 5 None None None 21223039 Common - glucosyltransferase SCO4658 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21220496 Common - pyruvate kinase SCO2014 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 21219678 Nonpathogen - integral membrane protein SCO1165 2 None None None 21220164 Nonpathogen - hypothetical protein SCO1668 2 None None None 21223605 Common - oxidoreductase SCO5237 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21225690 Common - hypothetical protein SCO7420 9 None None None 21220127 Common - helicase SCO1631 94 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 21219500 Common - malate synthase SCO0983 83 COG2225 AceB, Malate synthase Energy production and conversion 21223292 Common - hypothetical protein SCO4918 20 None None None 21218867 Nonpathogen - hypothetical protein SCO0319 1 None None None 21222835 Common - integral membrane protein SCO4447 34 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21220572 Common - hypothetical protein SCO2092 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 21220657 Common - 2-oxoacid dehydrogenase subunit E1 SCO2183 155 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 21221205 Common - LacI-family transcriptional regulator SCO2753 126 COG1609 PurR, Transcriptional regulators Transcription 21219922 Common - phosphodiesterase SCO1419 129 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 21220470 Common - hypothetical protein SCO1988 27 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 21218817 Common - transcriptional regulator SCO0266 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 21220909 Common - acetyl CoA carboxylase (alpha and beta subunits) SCO2445 172 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 21223124 Common - alanine racemase SCO4745 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 21219219 Common - oxidoreductase, molybdopterin binding subunit SCO0690 72 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 21222526 Common - ATP/GTP-binding protein SCO4127 10 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 21221280 Common - probable amino acid ABC transporter protein, integral membrane component SCO2830 170 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 21224162 Common - ABC transporter SCO5818 246 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21220765 Nonpathogen - integral membrane protein SCO2296 1 None None None 21223759 Common - acetyl-CoA acetyltransferase SCO5399 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 21223363 Common - hypothetical protein SCO4990 175 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21223326 Nonpathogen - hypothetical protein 2SCK3113 SCO4953 2 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21223744 Common - tetR-family transcriptional regulator SCO5384 11 COG1309 AcrR, Transcriptional regulator Transcription 21218778 Nonpathogen - hypothetical protein SCO0225 1 None None None 21225253 Common - lipase SCO6966 103 COG2267 PldB, Lysophospholipase Lipid metabolism 21220433 Common - zinc-binding carboxypeptidase SCO1948 28 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 21224482 Common - regulatory protein SCO6156 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21220669 Common - integral membrane protein SCO2196 19 None None None 21219043 Common nadE NAD synthetase SCO0506 117 COG0171 NadE, NAD synthase Coenzyme metabolism 21221961 Common - integral membrane protein with kinase activity SCO3542 233 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 21222326 Common - cystathionine gamma-lyase SCO3920 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 21219796 Common - integral membrane protein SCO1288 3 None None None 21221625 Common - mechanosensitive channel SCO3190 141 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 21219427 Common - dehydrogenase SCO0907 170 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 21225292 Common - oxidoreductase SCO7006 19 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 21218993 Common - SIR2-like regulatory protein SCO0452 151 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 21224774 Common - hypothetical protein SCO6470 75 COG2030 MaoC, Acyl dehydratase Lipid metabolism 21219476 Common - hypothetical protein SCO0958 28 None None None 21219781 Common - reductase SCO1273 44 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 21220947 Common - secreted protein SCO2484 19 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 21223975 Common - recombinase SCO5620 75 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 21221757 Common - epimerase SCO3326 63 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21219211 Common - hypothetical protein SCO0682 13 None None None 21220297 Nonpathogen - integral membrane protein SCO1807 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 21225593 Nonpathogen - hypothetical protein SCO7317 1 None None None 21225657 Common - transmembrane transport protein SCO7384 131 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 21218891 Common - racemase SCO0347 78 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 21224689 Common - lipoprotein SCO6377 4 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 21225997 Common - hypothetical protein SCO7738 181 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 21221903 Common - beta-galatosidase SCO3479 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 21218791 Nonpathogen - hypothetical protein SCO0238 1 None None None 32141274 Common - transcriptional regulator SCO5811 46 COG1309 AcrR, Transcriptional regulator Transcription 21225229 Nonpathogen - hypothetical protein SCO6942 2 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 21220910 Common - secreted peptidase SCO2446 140 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 21219261 Common - secreted protein SCO0736 14 None None None 21224593 Common - type I polyketide synthase SCO6273 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 21222165 Nonpathogen - integral membrane SCO3753 5 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 21223700 Nonpathogen - plasmid transfer protein SCO5339 6 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 21219060 Common - hypothetical protein SCO0525 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21224961 Common - secreted glucosidase SCO6665 38 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 21223085 Common rplB 50S ribosomal protein L2 SCO4705 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 21224100 Common - hypothetical protein SCO5754 189 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 21221410 Common - transport protein SCO2965 15 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21218712 Common - transcriptional regulatory protein SCO0155 65 COG1309 AcrR, Transcriptional regulator Transcription 21223281 Common - transcriptional regulatory protein SCO4907 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21218860 Common - acyl-CoA dehydrogenase SCO0312 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21224955 Common pgi glucose-6-phosphate isomerase SCO6659 180 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 21225058 Nonpathogen - lipoprotein SCO6765 6 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 21218876 Common - short chain oxidoreductase (secreted protein) SCO0331 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21223299 Nonpathogen - hypothetical protein SCO4925 1 None None None 21221015 Common - hypothetical protein SCO2556 33 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 21221827 Common - dihydroneopterin aldolase SCO3400 76 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 21219619 Common - tetR-family transcriptional regulatory protein SCO1104 22 COG1309 AcrR, Transcriptional regulator Transcription 21226071 Common - prolipoprotein diacylglyceryl transferase SCO7822 194 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 21221192 Nonpathogen - hypothetical protein SCO2739 2 None None None 21221698 Nonpathogen - hypothetical protein SCO3265 1 None None None 21224090 Common dapA dihydrodipicolinate synthase SCO5744 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 21224491 Common - hypothetical protein SCO6166 15 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 21224785 Common - hypothetical protein SCO6481 104 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 21222707 Nonpathogen - hypothetical protein SCO4314 1 None None None 21224077 Nonpathogen - hypothetical protein SCO5730 1 None None None 21225897 Nonpathogen - hypothetical protein SCO7636 1 None None None 21219524 Common - oxidoreductase SCO1007 61 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21220007 Common - recombination factor protein RarA SCO1506 208 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 21221767 Common - pyrroline-5-carboxylate reductase SCO3337 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 21222138 Common - hypothetical protein SCO3726 14 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 21225481 Nonpathogen - hypothetical protein SCO7204 1 None None None 21221419 Common - hypothetical protein SCO2975 26 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 21224267 Common - hypothetical protein SCO5928 21 COG3393 COG3393, Predicted acetyltransferase General function prediction only 21218956 Common - RNA polymerase sigma factor SCO0414 46 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21220482 Common - ATP-binding RNA helicase SCO2000 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 21221234 Common - monooxygenase SCO2783 58 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 21223070 Nonpathogen - hypothetical protein SCO4690 2 None None None 21224138 Common dapF diaminopimelate epimerase SCO5793 187 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 21222728 Common - marR-family protein SCO4336 49 COG1846 MarR, Transcriptional regulators Transcription 21221041 Common - hypothetical protein SCO2582 38 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 21221199 Common - bifunctional carbohydrate binding and transport protein SCO2747 170 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 21223551 Common - hypothetical protein SCO5182 20 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 21222905 Nonpathogen - hypothetical protein SCO4520 1 None None None 21220026 Common - lipid A biosynthesis lauroyl acyltransferase SCO1526 29 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 21219022 Common - monooxygenase SCO0484 74 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21221158 Nonpathogen - hypothetical protein SCO2703 1 None None None 21225286 Common - isocitrate dehydrogenase SCO7000 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 21223372 Nonpathogen - hypothetical protein SCO4999 1 None None None 21219315 Nonpathogen - hypothetical protein SCO0793 1 None None None 21220000 Common - integral membrane protein SCO1499 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 21222894 Nonpathogen - hypothetical protein SCO4509 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 21224413 Common - DNA polymerase III subunit epsilon SCO6084 82 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 21224367 Common - lysine/ornithine decarboxylase SCO6035 166 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 21221167 Nonpathogen - hypothetical protein SCO2712 1 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 21222229 Nonpathogen - hypothetical protein SCO3819 1 None None None 21225035 Common - oxidoreductase SCO6741 3 None None None 21222890 Common - cold shock protein SCO4505 181 COG1278 CspC, Cold shock proteins Transcription 21222240 Common - branched-chain alpha keto acid dehydrogenase E1 beta subunit SCO3830 210 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 21223065 Common - DEAD-box RNA helicase SCO4685 229 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 21219167 Common - ABC transporter ATP-binding protein SCO0636 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 21220631 Common - integral membrane protein SCO2154 18 None None None 21225816 Common - tetR-family transcriptional regulator SCO7552 36 COG1309 AcrR, Transcriptional regulator Transcription 21223624 Common - methyltransferase SCO5257 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21218983 Common - hypothetical protein SCO0441 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 32141159 Common - integral membrane efflux protein SCO2164 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 21225670 Common - binding-protein-dependent transport lipoprotein SCO7399 77 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 21226038 Common - hypothetical protein SCO7787 6 None None None 21220133 Common - hypothetical protein SCO1637 31 COG2378 COG2378, Predicted transcriptional regulator Transcription 21221541 Common - eukaryotic-type protein kinase SCO3102 147 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21223227 Nonpathogen - hypothetical protein SCO4851 3 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 21219339 Common - ABC transporter ATP-binding protein SCO0818 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 21225653 Common - hypothetical protein SCO7380 92 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21223220 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase SCO4844 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 32141146 Common - acetyltransferase SCO1545 24 COG0456 RimI, Acetyltransferases General function prediction only 21224072 Nonpathogen - hypothetical protein SCO5725 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 21225018 Common - hypothetical protein SCO6724 12 None None None 21218804 Nonpathogen - hypothetical protein SCO0251 1 None None None 21219712 Common ligB ATP-dependent DNA ligase SCO1202 110 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 21220153 Common - methionine synthase SCO1657 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 21224131 Common - secreted hydrolase SCO5786 14 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 21219604 Common - hypothetical protein 2SCG405c SCO1089 7 None None None 32141344 Common - ATP/GTP-binding protein SCO7841 5 None None None 21219646 Common - oxidoreductase SCO1132 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 21221322 Common - hypothetical protein SCO2873 20 COG0456 RimI, Acetyltransferases General function prediction only 21220892 Common - secreted arabinase SCO2427 39 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 21221667 Nonpathogen - phosphotransferase SCO3234 2 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 21220452 Common - secreted hydrolase SCO1968 176 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 21220913 Common - hypothetical protein SCO2449 85 COG0714 COG0714, MoxR-like ATPases General function prediction only 21223041 Common - 30S ribosomal protein S7 SCO4660 241 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 21221668 Common - ABC transporter SCO3235 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 21222011 Common - D-alanine:D-lactate ligase SCO3595 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 21224841 Common - hypothetical protein SCO6539 32 COG1476 COG1476, Predicted transcriptional regulators Transcription 21225150 Nonpathogen - hypothetical protein SCO6859 1 None None None 21221030 Common leuS leucyl-tRNA synthetase SCO2571 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21223288 Common - deoxyribose-phosphate aldolase SCO4914 134 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 21224260 Common - cold-shock domain protein SCO5921 181 COG1278 CspC, Cold shock proteins Transcription 21219233 Common - branched-chain amino acid ABC transport permease SCO0707 113 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 21220499 Common - amino acid decarboxylase SCO2017 128 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 21220324 Nonpathogen - hypothetical protein SCO1835 1 None None None 21219173 Common - secreted cellulose-binding protein SCO0643 14 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 21224991 Common - 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase SCO6697 129 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 21219302 Common - hypothetical protein SCO0779 12 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 21224405 Common - hypothetical protein SCO6075 46 COG1409 Icc, Predicted phosphohydrolases General function prediction only 21222206 Common aspS aspartyl-tRNA synthetase SCO3795 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 21220359 Common - aldehyde dehydrogenase SCO1871 176 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 21221019 Common - hypothetical protein SCO2560 47 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221462 Common - lipoprotein SCO3019 88 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 21225479 Common - transcriptional regulator SCO7201 46 COG1846 MarR, Transcriptional regulators Transcription 21221774 Common - serine/threonine protein kinase SCO3344 174 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 21221333 Common - cytochrome P450 SCO2884 90 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 21225168 Nonpathogen - hypothetical protein SCO6877 3 COG1475 Spo0J, Predicted transcriptional regulators Transcription 21219190 Common - probable solute-binding lipoprotein SCO0660 72 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21225053 Common - phytoene synthase SCO6760 112 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 21219278 Common - secreted protein SCO0754 15 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 21221092 Common - aminopeptidase SCO2635 162 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 21223344 Common - dehydrogenase SCO4971 121 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 21223524 Nonpathogen - lipoprotein SCO5155 1 None None None 21219390 Nonpathogen - anti-sigma factor antagonist SCO0869 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 32141250 Common - sugar transferase SCO4875 199 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 21220173 Common - hypothetical protein SCO1677 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 21221364 Common - nicotinate phosphoribosyltransferase SCO2917 103 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 21220383 Common - hypothetical protein SCO1896 66 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 32141281 Common - secreted ATP/GTP binding protein SCO6004 27 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 21224514 Common - transferase SCO6190 68 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 21221091 Common - hypothetical protein SCO2634 16 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 21218658 Common - transcriptional regulator SCO0089 191 COG0583 LysR, Transcriptional regulator Transcription 21218908 Common - enoyl-CoA hydratase SCO0364 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 21220270 Common - transcriptional regulator SCO1778 28 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 21223379 Common - septum site-determining protein SCO5006 6 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 21223775 Common - isobutyryl-CoA mutase A SCO5415 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 21223771 Common - integrase/recombinase SCO5411 76 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 21219422 Common - hypothetical protein SCO0902 23 None None None 21221931 Common - DNA methylase SCO3510 108 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 21221682 Nonpathogen - acyl carrier protein SCO3249 3 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21224438 Nonpathogen - secreted hydrolase SCO6109 4 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 21222032 Common - hypothetical protein SCO3616 6 None None None 21219651 Common - two component system histidine kinase SCO1137 146 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 21220711 Common - probable glutamine synthetase SCO2241 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 21220407 Common - aminotransferase SCO1921 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 21224698 Nonpathogen - hypothetical protein SCO6386 3 None None None 21218617 Nonpathogen - sigma factor SCO0038 1 None None None 21223865 Common - oxidoreductase SCO5509 172 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 21223698 Common - hypothetical protein SCO5337 6 None None None 21218730 Nonpathogen - hypothetical protein SCO0173 7 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 21221377 Common - permease membrane component SCO2930 150 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 21225483 Nonpathogen - membrane protein SCO7206 1 None None None 21221616 Common moaC molybdenum cofactor biosynthesis protein C SCO3180 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 21223388 Common - secreted protein SCO5015 141 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 21220991 Common - beta-glucosidase SCO2531 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 21223078 Common - IS1652 transposase SCO4698 80 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 21219639 Nonpathogen - hypothetical protein 2SCG3818c SCO1125 2 COG5502 COG5502, Uncharacterized conserved protein Function unknown 21222069 Common - two-component system sensor kinase SCO3654 110 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 21219241 Nonpathogen - hypothetical protein SCO0715 1 None None None 21223731 Common - F0F1 ATP synthase subunit alpha SCO5371 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 21222919 Nonpathogen - integral membrane protein SCO4535 1 None None None 21218766 Nonpathogen - hypothetical protein SCO0212 6 None None None 21220845 Common - merR-family transciptional regulator SCO2378 88 COG0789 SoxR, Predicted transcriptional regulators Transcription 21225387 Common - RNA polymerase sigma factor SCO7105 47 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21223315 Common - regulatory protein SCO4942 56 COG1309 AcrR, Transcriptional regulator Transcription 21222539 Common - phosphate ABC transport system permease protein SCO4141 228 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 21220685 Common - regulatory protein SCO2213 197 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 21222785 Common - hydrolase SCO4395 171 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 21222517 Common - tetR-family transcriptional regulator SCO4118 7 COG1309 AcrR, Transcriptional regulator Transcription 21218693 Nonpathogen - hypothetical protein SCO0133 1 None None None 21225615 Nonpathogen - hypothetical protein SCO7340 3 None None None 21225995 Common - integral membrane protein SCO7736 10 COG1289 COG1289, Predicted membrane protein Function unknown 21221885 Common - oxidoreductase SCO3460 237 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 21219014 Common - lipoprotein SCO0474 12 None None None 21225063 Common - DNA-binding protein SCO6770 16 COG1476 COG1476, Predicted transcriptional regulators Transcription 21223396 Nonpathogen - secreted protein SCO5023 4 None None None 21219097 Common - hypothetical protein SCO0563 13 COG3831 COG3831, Uncharacterized conserved protein Function unknown 21219309 Nonpathogen - integral membrane protein SCO0786 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 21218929 Common - asparagine synthetase SCO0386 198 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 21219493 Common - hypothetical protein SCO0976 12 None None None 21223639 Nonpathogen - hypothetical protein 2SC7G1134 SCO5272 1 None None None 21223448 Common - hypothetical protein SCO5077 4 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 21223470 Common - hypothetical protein SCO5099 6 None None None 21220038 Common - transport system membrane protein SCO1538 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 21222385 Common - GntR-family transcriptional regulator SCO3981 109 COG2188 PhnF, Transcriptional regulators Transcription 21225244 Common - putative monovalent cation/H+ antiporter subunit E SCO6957 21 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 21220011 Common - peptidyl-prolyl cis-trans isomerase SCO1510 192 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 21225299 Common - probable LacI-family transcriptional regulatory protein SCO7014 125 COG1609 PurR, Transcriptional regulators Transcription 21223094 Common rplE 50S ribosomal protein L5 SCO4714 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 21220303 Common - gntR-family transcriptional regulator SCO1813 143 COG2186 FadR, Transcriptional regulators Transcription 32141244 Nonpathogen - hypothetical protein SCO4676 1 None None None 21222409 Common - acyl-CoA synthetase SCO4006 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 21222490 Common - hypothetical protein SCO4088 12 None None None 21223050 Nonpathogen - hypothetical protein SCO4669 1 None None None 21223191 Common purN phosphoribosylglycinamide formyltransferase SCO4813 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 21220444 Common - mycothiol-dependent maleylpyruvate isomerase SCO1959 12 None None None 21222804 Nonpathogen - integral membrane protein SCO4415 1 None None None 21219019 Common - phosphatase SCF7619c SCO0479 116 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 21220902 Common - secreted protein SCO2438 19 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 21219363 Common - deoxyribodipyrimidine photolyase SCO0842 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 21224817 Nonpathogen - hypothetical protein SCO6514 4 None None None 21221923 Common - 3-oxoacyl-[acyl carrier protein] reductase SCO3502 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21221782 Common - hypothetical protein SCO3353 8 None None None 21224052 Common - hypothetical protein SCO5703 48 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 21219512 Common - methyltransferase SCO0995 192 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 21218901 Common - probable GntR-family regulator (secreted protein) SCO0357 125 COG2186 FadR, Transcriptional regulators Transcription 21218681 Common - ABC transport system ATP-binding protein SCO0121 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21222510 Common - integral membrane protein SCO4110 10 COG2339 COG2339, Predicted membrane protein Function unknown 21220718 Common - hypothetical protein SCO2248 8 None None None 21218937 Common - hypothetical protein SCO0394 16 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 21221246 Common - sugar binding secreted protein SCO2795 32 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 21222172 Nonpathogen - hypothetical protein SCO3761 1 None None None 21223019 Common - hypothetical protein SCO4637 45 COG2030 MaoC, Acyl dehydratase Lipid metabolism 21225964 Common - oxidoreductase SCO7705 64 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21222247 Common - hypothetical protein SCO3838 2 None None None 21223217 Common - short-chain dehydrogenase SCO4841 188 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21224193 Common - AgaS protein SCO5849 65 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 21223012 Common - hypothetical protein SCO4629 18 COG1434 COG1434, Uncharacterized conserved protein Function unknown 21225389 Common - hypothetical protein SCO7107 116 COG2353 COG2353, Uncharacterized conserved protein Function unknown 21223195 Nonpathogen - hypothetical protein SCO4818 1 None None None 21219053 Common - hypothetical protein SCO0518 24 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 21219663 Common rpmE2 50S ribosomal protein L31 type B SCO1150 139 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 21224569 Common - allantoicase SCO6248 15 COG4266 Alc, Allantoicase Nucleotide transport and metabolism 21224682 Nonpathogen - integral membrane protein SCO6370 1 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 21220536 Nonpathogen - hypothetical protein SCO2055 5 None None None 21224276 Common - hypothetical protein SCO5938 18 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 21218773 Common - nitrate reductase delta chain NarI2 SCO0219 57 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 21222746 Common - nucleotidyltransferase SCO4355 25 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 21220236 Common - ABC-transporter ATP-binding protein SCO1742 248 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 21225581 Common - hypothetical protein SCO7305 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 21219917 Common - ankyrin-like protein SCO1414 35 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 21219892 Common - mannose-1-phosphate guanyltransferase SCO1388 242 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 21224298 Nonpathogen - cobalt transport protein CbiN SCO5960 2 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 21222440 Nonpathogen - small membrane protein SCO4037 1 None None None 21223691 Common - hypothetical protein SCO5329 73 COG1479 COG1479, Uncharacterized conserved protein Function unknown 21222801 Common - regulatory protein SCO4412 6 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 21225321 Nonpathogen - integral membrane protein SCO7038 2 None None None 21221559 Nonpathogen - hypothetical protein SCO3120 1 None None None 21223495 Common - hypothetical protein SCO5125 6 None None None 21223632 Common - hypothetical protein SCO5265 22 COG3595 COG3595, Uncharacterized conserved protein Function unknown 21224498 Common - permease SC6C509 SCO6173 139 COG2252 COG2252, Permeases General function prediction only 21225380 Nonpathogen - hypothetical protein SCO7098 1 None None None 21225401 Common - dehydrogenase SCO7119 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 21220565 Common - cell division protein SCO2085 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 21222062 Common - hypothetical protein SCO3647 14 None None None 21223234 Common - succinate dehydrogenase membrane subunit SCO4858 19 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 21221294 Nonpathogen - hypothetical protein SCO2844 1 None None None 21219972 Nonpathogen - hypothetical protein SCO1470 1 None None None 21221720 Nonpathogen - integral membrane protein SCO3288 1 None None None 21223618 Common - acetyltransferase SCO5251 15 COG0456 RimI, Acetyltransferases General function prediction only 21222364 Nonpathogen - integral membrane protein SCO3959 3 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 21225926 Common - hypothetical protein SCO7665 20 None None None 21221000 Common - probable transmembrane transport protein SCO2541 95 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 21223059 Common - hypothetical protein SCO4679 5 None None None 21219693 Nonpathogen - hypothetical protein SCO1182 2 None None None 21224560 Common - sigma factor SCO6239 53 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 21225598 Common - anti-sigma factor antagonist SCO7323 30 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 21221994 Common - hypothetical protein SCO3576 16 None None None 21224762 Common - hydrolytic protein SCO6456 16 None None None 21220235 Common - secreted serine protease SCO1741 10 None None None 21221866 Common - hypothetical protein SCO3440 73 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 21224119 Common - monooxygenase SCO5773 55 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 21219058 Common - transcriptional regulator SCO0523 150 COG1522 Lrp, Transcriptional regulators Transcription 21222052 Nonpathogen - hypothetical protein SCO3637 1 None None None 21223368 Nonpathogen - hypothetical protein SCO4995 1 None None None 21225161 Nonpathogen - hypothetical protein SCO6870 1 None None None 21222739 Common - hypothetical protein SCO4348 9 None None None 21221977 Common - morphological differentiation-associated protein SCO3558 80 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 21220726 Common - probable ABC transporter, ATP-binding component SCO2257 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 32141257 Common - histidine kinase SCO5239 96 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 21223243 Common - lipoprotein SCO4868 16 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 21221730 Common - oxidoreductase SCO3298 184 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 21226011 Nonpathogen - hypothetical protein SCO7755 1 None None None 21220199 Common - integral membrane conserved hypothetical protein SCO1704 19 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 21222821 Common - integral membrane protein SCO4433 2 None None None 21220950 Common - nitrite reductase large subunit NirB SCO2487 190 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 21221440 Common - ABC transporter ATP-binding protein SCO2996 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 21222936 Nonpathogen - hypothetical protein SCO4553 1 None None None 21221146 Nonpathogen - hypothetical protein SCO2691 2 None None None 21222183 Common - secreted protein SCO3772 20 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 21219036 Common - peptide monooxygenase SCO0498 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 21224330 Common - hypothetical protein SCO5993 107 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 21225438 Common - hypothetical protein SCO7158 133 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21221989 Common - transcriptional regulator SCO3571 168 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 21219732 Common - hypothetical protein SCO1222 33 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 21222723 Common - hypothetical protein SCO4331 8 None None None 21220686 Common - reductase SCO2214 50 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21220187 Common - oxidoreductase SCO1692 169 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 21220390 Common - transport associated protein SCO1903 28 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 21221708 Common - merR-family transcriptional regulator SCO3275 141 COG0789 SoxR, Predicted transcriptional regulators Transcription 21220746 Common - hypothetical protein SCO2277 81 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 21224337 Nonpathogen - hypothetical protein SCO6001 1 None None None 21224343 Common - probable transcriptional repressor protein SCO6008 175 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 21225712 Nonpathogen - hypothetical protein SCO7442 1 None None None 21220730 Nonpathogen - membrane protein SCO2261 1 None None None 21225470 Common - secreted protein SCO7191 46 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 21220118 Common - 5'-3' exonuclease SCO1622 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 21222059 Common - lipase/esterase SCO3644 15 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 21225732 Common - sensor histidine kinase SCO7463 10 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 21221010 Nonpathogen - hypothetical protein SCO2551 1 None None None 21219681 Common - xylose isomerase SCO1169 75 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 21220737 Common - hypothetical protein SCO2268 30 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 21219194 Common - hypothetical protein SCO0664 18 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 21219938 Common - integral membrane protein SCO1435 203 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 21220191 Common - hypothetical protein SCO1696 8 COG3246 COG3246, Uncharacterized conserved protein Function unknown 21223024 Nonpathogen - hypothetical protein SCO4642 2 None None None 21223383 Common - integral membrane protein SCO5010 15 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 21225077 Common - regulatory protein SCO6784 66 COG1309 AcrR, Transcriptional regulator Transcription 21220244 Common - transmembrane transport protein SCO1751 121 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 21221482 Common - nucleotide phosphorylase SCO3039 238 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 21225861 Nonpathogen - hypothetical protein SCO7598 1 None None None 21225870 Common - hypothetical protein SCO7608 16 None None None 21220018 Common ruvB Holliday junction DNA helicase B SCO1518 213 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 21220418 Common - hypothetical protein SCO1932 7 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 21220708 Common - lyase SCO2237 25 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 21221023 Common - DNA-binding protein SCO2564 31 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 21225564 Nonpathogen - hypothetical protein SCO7287 1 None None None 21225803 Common - LysR-family transcriptional regulator SCO7538 168 COG0583 LysR, Transcriptional regulator Transcription 21221739 Common - DNA-binding protein SCO3308 2 COG1396 HipB, Predicted transcriptional regulators Transcription 21224886 Common - succinyl-CoA synthetase subunit alpha SCO6586 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 21225601 Common - hypothetical protein SCO7326 93 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21226006 Common - hypothetical protein SCO7749 22 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 21221173 Nonpathogen - secreted protein SCO2719 1 None None None 21224183 Common - hypothetical protein SCO5839 183 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 21224758 Common - transport permease protein SCO6452 216 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 21220047 Common - hypothetical protein SCO1548 5 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 21223445 Common - oxidoreductase SCO5073 163 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 21223787 Common - integral membrane transport protein SCO5428 164 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 21225458 Common - secreted amidase SCO7179 47 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 21223058 Common - hypothetical protein SCO4678 6 None None None 21222532 Common - integral membrane protein SCO4133 96 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 21219077 Common - hypothetical regulatory protein SCO0542 89 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 21225362 Nonpathogen - insertion element transposase SCO7080 4 None None None 21219048 Common - regulatory protein SCO0512 39 COG1309 AcrR, Transcriptional regulator Transcription 21222252 Common - hypothetical protein SCO3843 31 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 21219632 Common - integral membrane protein SCO1118 7 COG1289 COG1289, Predicted membrane protein Function unknown 21219746 Nonpathogen - hypothetical protein SCO1237 4 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 21223184 Nonpathogen - secreted protein SCO4806 1 None None None 21222499 Common - acetyltransferase SCO4098 158 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 21225441 Common - 3-oxoacyl-[acyl-carrier protein] reductase SCO7161 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 21225814 Common - secreted hydrolase SCO7550 166 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 21218600 Nonpathogen - hypothetical protein SCO0018 5 None None None 21222502 Nonpathogen - secreted protein SCO4101 1 None None None 21223897 Common - hypothetical protein SCO5542 9 None None None 21221499 Common - dipeptidase SCO3057 89 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 21221729 Common - hypothetical protein SCO3297 79 COG1742 COG1742, Uncharacterized conserved protein Function unknown 21224042 Common - acyl CoA dehydrogenase SCO5693 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 21218602 Nonpathogen - hypothetical protein SCO0021 1 None None None 21220975 Nonpathogen - hypothetical protein SCO2514 4 None None None 21221804 Common - Lsr2-like protein SCO3375 17 None None None 21220214 Common - ABC-transporter transmembrane protein SCO1720 52 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 21224248 Common - hypothetical protein SCO5909 3 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 21224431 Common - nitrite/sulphite reductase SCO6102 170 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism