Methanosarcina acetivorans C2A, complete genome NC_003552 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 20090037 Common - hypothetical protein MA1171 103 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 20090836 Nonpathogen - hypothetical protein MA1988 1 None None None 20092999 Common glnB nitrogen regulatory protein P-II MA4208 186 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20089365 Nonpathogen - hypothetical protein MA0476 2 None None None 20089186 Nonpathogen - hypothetical protein MA0288 1 None None None 20092028 Common trx thioredoxin MA3212 228 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 20090700 Common - iron(III) ABC transporter, solute-binding protein MA1850 94 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20090178 Common putP sodium:proline symporter (proline permease) MA1316 154 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 20090171 Common - metal-dependent hydrolase MA1308 107 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 20091236 Nonpathogen - hypothetical protein MA2405 1 None None None 20093296 Common guaA GMP synthase subunit B MA4511 238 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 20092977 Common - reverse transcriptase MA4185 79 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20091493 Common - hypothetical protein MA2670 16 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090952 Common - LysE type translocator MA2108 52 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 20090308 Common - hypothetical protein MA1449 40 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 20092489 Nonpathogen purP 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase MA3689 20 COG1759 COG1759, ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) General function prediction only 20089967 Nonpathogen - hypothetical protein MA1097 1 COG1497 COG1497, Predicted transcriptional regulator Transcription 20092119 Common - cytochrome c-type synthesis protein MA3304 175 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 20090633 Nonpathogen rnpA ribonuclease P protein component 3 MA1782 22 COG1603 RPP1, RNase P/RNase MRP subunit p30 Translation, ribosomal structure and biogenesis 20088913 Common cheA2 chemotaxis sensor histidine kinase MA0014 155 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 20090091 Common - ABC transporter, ATP-binding protein MA1227 241 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20090934 Nonpathogen - hypothetical protein MA2089 1 None None None 20090449 Common - surface antigen gene MA1591 95 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20093372 Common - cell surface protein MA4588 91 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089979 Common rps11p 30S ribosomal protein S11P MA1110 246 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 20091821 Nonpathogen - hypothetical protein MA3003 1 None None None 20091086 Common - squamous cell carcinoma antigen MA2246 30 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 20092822 Nonpathogen - hypothetical protein MA4028 6 COG5513 COG5513, Predicted secreted protein Function unknown 20089506 Common - cation efflux system protein MA0617 212 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 20092274 Common - ABC transporter, solute-binding protein MA3461 215 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20089252 Common - transcriptional regulator, TetR family MA0354 112 COG1309 AcrR, Transcriptional regulator Transcription 20089497 Common ppdK pyruvate phosphate dikinase MA0608 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 20091192 Common - hypothetical protein MA2359 15 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 20092589 Common leuA (R)-citramalate synthase MA3793 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 20091736 Common - cell surface protein MA2916 42 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092165 Nonpathogen - hypothetical protein MA3351 1 None None None 20092992 Nonpathogen - hypothetical protein MA4201 9 COG4273 COG4273, Uncharacterized conserved protein Function unknown 20093169 Common - CobW protein MA4382 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 20089024 Nonpathogen - hypothetical protein MA0125 8 None None None 20092137 Common uvrB excinuclease ABC subunit B MA3323 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 20091475 Common - hypothetical protein MA2652 10 COG4449 COG4449, Predicted protease of the Abi (CAAX) family General function prediction only 20093215 Common serB phosphoserine phosphatase MA4429 154 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 20090624 Common - nitroreductase MA1774 136 COG0778 NfnB, Nitroreductase Energy production and conversion 20091434 Nonpathogen - hypothetical protein MA2608 1 None None None 20089854 Common frhG coenzyme F420 hydrogenase, subunit gamma MA0977 71 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 20092963 Common - hypothetical protein MA4170 17 COG1145 NapF, Ferredoxin Energy production and conversion 20089996 Common - iron ABC transporter, solute-binding protein MA1130 55 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20089444 Nonpathogen - hypothetical protein MA0555 2 None None None 20092350 Common - sensory transduction histidine kinase MA3543 175 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089685 Nonpathogen - hypothetical protein MA0801 1 None None None 20093255 Common - hypothetical protein MA4469 27 COG3503 COG3503, Predicted membrane protein Function unknown 20092763 Nonpathogen - hypothetical protein MA3968 8 COG4746 COG4746, Uncharacterized protein conserved in archaea Function unknown 20090155 Common - hypothetical protein MA1291 42 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 20090599 Common - cobalt ABC transporter, ATP-binding protein MA1747 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20090773 Nonpathogen - hypothetical protein MA1924 3 None None None 20091723 Common - transcriptional regulator, TetR family MA2902 81 COG1309 AcrR, Transcriptional regulator Transcription 20092017 Common hisD histidinol dehydrogenase MA3201 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 20089262 Common - outer membrane protein expression inhibitor MA0365 104 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 20092852 Common sui1 translation initiation factor Sui1 MA4059 80 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 20091967 Nonpathogen - hypothetical protein MA3149 3 None None None 20090152 Common rrmJ 23S RNA methyltransferase J MA1288 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 20093108 Common - hypothetical protein MA4319 23 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 20091418 Nonpathogen - hypothetical protein MA2592 1 None None None 20089280 Common - protoporphyrin IX magnesium chelatase MA0383 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20091283 Nonpathogen - hypothetical protein MA2452 2 None None None 20091446 Common - hypothetical protein MA2620 2 None None None 20090441 Common gyrA DNA topoisomerase (ATP-hydrolyzing), subunit A MA1583 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 20092644 Common - hypothetical protein MA3848 15 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089278 Common fwdE formylmethanofuran dehydrogenase, subunit E MA0381 38 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 20091863 Common - hypothetical protein MA3045 28 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 20093135 Common menG menaquinone biosynthesis methyltransferase (2-heptaprenyl-1, 4-naphthoquinone methyltransferase) MA4347 222 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20093184 Nonpathogen - hypothetical protein MA4397 11 COG4742 COG4742, Predicted transcriptional regulator Transcription 20091072 Common - hypothetical protein MA2232 6 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 20092792 Nonpathogen - hypothetical protein MA3997 14 COG4070 COG4070, Predicted peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family Posttranslational modification, protein turnover, chaperones 20092809 Common - DNA-(apurinic or apyrimidinic site) lyase MA4014 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 20090136 Common - hypothetical protein MA1272 93 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 20093325 Common - Mrr restriction system protein MA4541 45 COG1715 Mrr, Restriction endonuclease Defense mechanisms 20089872 Common - hypothetical protein MA0995 30 COG3910 COG3910, Predicted ATPase General function prediction only 20092480 Common - sulfate adenylyltransferase (ADP) MA3680 77 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 20092474 Common - N-acetyltransferase MA3674 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 20089789 Nonpathogen - hypothetical protein MA0911 1 None None None 20091067 Nonpathogen - hypothetical protein MA2227 1 None None None 20089301 Common - hypothetical protein MA0407 30 COG0716 FldA, Flavodoxins Energy production and conversion 20093062 Nonpathogen nusG transcription antitermination protein NusG MA4273 34 COG0250 NusG, Transcription antiterminator Transcription 20093196 Common - hypothetical protein MA4409 79 COG0348 NapH, Polyferredoxin Energy production and conversion 20092285 Nonpathogen - hypothetical protein MA3474 1 None None None 20092921 Nonpathogen - hypothetical protein MA4128 1 None None None 20093430 Common - hypothetical protein MA4651 128 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 20089879 Common - Fmn oxidoreductase protein MA1003 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 20093121 Nonpathogen - hypothetical protein MA4333 28 COG1354 COG1354, Uncharacterized conserved protein Function unknown 20089679 Common - hypothetical protein MA0795 103 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 20091626 Nonpathogen - hypothetical protein MA2804 2 None None None 20090665 Nonpathogen - hypothetical protein MA1814 1 None None None 20093361 Common - cell surface protein MA4577 56 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20091456 Common - Na+/H+ antiporter MA2633 92 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 20089557 Nonpathogen hmaA archaeal histone MA0672 22 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 20091680 Nonpathogen - hypothetical protein MA2856 1 None None None 20088933 Common porG pyruvate ferredoxin oxidoreductase subunit gamma MA0034 93 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 20090314 Nonpathogen trm1 N(2),N(2)-dimethylguanosine tRNA methyltransferase MA1455 38 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 20091315 Common - peptide ABC transporter, permease protein MA2484 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20092982 Common - hypothetical protein MA4191 19 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 20089259 Common - hypothetical protein MA0362 33 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 20089404 Nonpathogen - hypothetical protein MA0515 4 None None None 20092063 Common - hypothetical protein MA3247 203 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 20089737 Common bcrA bacitracin ABC transporter, ATP-binding protein MA0853 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20092112 Common thrC threonine synthase MA3297 86 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 20089528 Common - hypothetical protein MA0641 34 COG1379 COG1379, Uncharacterized conserved protein Function unknown 20092536 Nonpathogen - hypothetical protein MA3738 1 None None None 20091712 Common - sensory transduction histidine kinase MA2890 156 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092036 Nonpathogen - hypothetical protein MA3220 2 None None None 20090784 Common - hypothetical protein MA1935 18 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 20093392 Common - bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase MA4608 64 COG1795 COG1795, Uncharacterized conserved protein Function unknown 20092897 Common - hypothetical protein MA4104 63 COG3272 COG3272, Uncharacterized conserved protein Function unknown 20090604 Common - ABC transporter, ATP-binding protein MA1752 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20089843 Common - thioredoxin MA0965 191 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 20090406 Common - hypothetical protein MA1548 4 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20091378 Nonpathogen - hypothetical protein MA2551 9 COG4742 COG4742, Predicted transcriptional regulator Transcription 20091717 Common thrS threonyl-tRNA synthetase MA2896 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20090330 Nonpathogen ef1B elongation factor 1-beta MA1471 31 COG2092 EFB1, Translation elongation factor EF-1beta Translation, ribosomal structure and biogenesis 20090744 Nonpathogen - hypothetical protein MA1894 1 None None None 20090793 Common - hypothetical protein MA1944 24 COG1808 COG1808, Predicted membrane protein Function unknown 20089108 Common - hypothetical protein MA0210 12 COG3377 COG3377, Uncharacterized conserved protein Function unknown 20091912 Common pstC phosphate ABC transporter, permease protein MA3094 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 20093266 Common - cell surface protein MA4481 10 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20091703 Common - GufA protein MA2881 92 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 20089546 Common nqr1 Na+-transporting NADH:ubiquinone oxidoreductase, subunit 1 MA0659 72 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 20093311 Nonpathogen - hypothetical protein MA4526 1 None None None 20089434 Nonpathogen - hypothetical protein MA0545 18 COG1326 COG1326, Uncharacterized archaeal Zn-finger protein General function prediction only 20090985 Common argG argininosuccinate synthase MA2142 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 20093359 Common cdc48 cell division control protein 48 MA4575 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 20089688 Common - hypothetical protein MA0804 10 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092367 Common - 8-oxoguanine DNA glycosylase MA3561 21 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 20091525 Common - transposase MA2701 38 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 20092948 Common atpE V-type ATP synthase subunit E MA4155 30 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 20090809 Common - cell surface glycoprotein (S-layer protein) MA1961 62 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20092280 Common - methyltransferase MA3467 25 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 20092360 Nonpathogen cbiN cobalt transport protein CbiN MA3553 2 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 20090369 Common - hypothetical protein MA1510 50 COG5276 COG5276, Uncharacterized conserved protein Function unknown 20092777 Nonpathogen - hypothetical protein MA3983 1 COG4854 COG4854, Predicted membrane protein Function unknown 20089473 Common - dihydroorotate dehydrogenase electron transfer subunit MA0584 90 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 20092381 Common - hypothetical protein MA3577 65 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 20091792 Nonpathogen - hypothetical protein MA2974 1 None None None 20092260 Common - moaA/nifB/pqqE family protein MA3448 92 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 20092540 Common - hypothetical protein MA3742 21 COG1633 COG1633, Uncharacterized conserved protein Function unknown 20090472 Common - hypothetical protein MA1614 115 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 20089117 Common hisB imidazoleglycerol-phosphate dehydratase MA0219 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 20091298 Common - hypothetical protein MA2467 19 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 20088968 Common hypE hydrogenase expression/formation protein MA0069 211 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 20090027 Common mef macrolide-efflux protein MA1161 182 None None None 20090755 Nonpathogen - hypothetical protein MA1906 3 None None None 20092576 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase MA3780 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 20090075 Common nifI2 P-II family nitrogen regulatory protein MA1211 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20091045 Common - hypothetical protein MA2204 15 COG1285 SapB, Uncharacterized membrane protein Function unknown 20092441 Common - iron ABC transporter, permease MA3641 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20090457 Common - hypothetical protein MA1599 13 COG5513 COG5513, Predicted secreted protein Function unknown 20091243 Common - hypothetical protein MA2412 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 20090816 Common - hypothetical protein MA1968 122 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 20091613 Nonpathogen - hypothetical protein MA2790 1 None None None 20089427 Common - peptidase family protein U32 MA0538 141 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 20092267 Common nikA nickel ABC transporter, solute-binding protein MA3455 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20088981 Nonpathogen - hypothetical protein MA0082 1 None None None 20093141 Common phoA alkaline phosphatase MA4354 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 20093394 Nonpathogen - hypothetical protein MA4610 1 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 20092039 Nonpathogen - hypothetical protein MA3223 1 None None None 20089808 Nonpathogen - transmembrane protein MttP MA0930 2 None None None 20090729 Common - hypothetical protein MA1879 12 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090092 Common - hypothetical protein MA1228 25 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 20089661 Common - signal-transducing histidine kinase MA0777 149 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20092861 Common - bacterioferritin comigratory protein Bcp MA4068 214 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 20089630 Common - hypothetical protein MA0745 6 None None None 20093151 Common - corrinoid protein MA4364 53 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20090460 Common - mutT/NUDIX family protein MA1602 38 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 20092423 Nonpathogen - hypothetical protein MA3623 4 COG4921 COG4921, Uncharacterized protein conserved in archaea Function unknown 20090889 Nonpathogen - hypothetical protein MA2042 1 None None None 20091345 Nonpathogen - hypothetical protein MA2517 26 COG2433 COG2433, Uncharacterized conserved protein Function unknown 20091090 Nonpathogen - hypothetical protein MA2251 5 COG0392 COG0392, Predicted integral membrane protein Function unknown 20093162 Nonpathogen - hypothetical protein MA4375 11 COG4742 COG4742, Predicted transcriptional regulator Transcription 20093271 Nonpathogen - hypothetical protein MA4486 1 None None None 20088957 Common - hypothetical protein MA0058 35 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 20092151 Common - hypothetical protein MA3337 3 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090485 Common - sensory transduction histidine kinase MA1630 181 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20093379 Common - prephenate dehydrogenase MA4595 145 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 20089326 Nonpathogen - hypothetical protein MA0434 1 None None None 20090291 Common - methionine sulfoxide reductase A MA1431 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 20091901 Nonpathogen flaJ flagellar assembly protein J MA3083 18 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 20091662 Nonpathogen - hypothetical protein MA2838 18 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20091121 Common - isochorismatase MA2283 99 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 20092690 Common - bacteriochlorophyll synthase MA3894 113 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20090286 Common - NADH peroxidase MA1426 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 20091956 Common - peptidylprolyl isomerase MA3138 111 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 20090243 Nonpathogen - hypothetical protein MA1382 14 COG3365 COG3365, Uncharacterized protein conserved in archaea Function unknown 20091341 Common topA DNA topoisomerase I MA2510 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 20091731 Common vorB 2-ketoisovalerate ferredoxin reductase MA2910 122 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 20092101 Common - universal stress protein MA3286 129 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20090852 Common - FtsJ-like methyltransferase MA2004 39 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 20091422 Nonpathogen - hypothetical protein MA2596 1 None None None 20089975 Common - gliding motility protein MA1106 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20090358 Common fpoH F(420)H(2) dehydrogenase, subunit FpoH MA1499 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 20093339 Common rbcL ribulose bisophosphate carboxylase MA4555 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 20091693 Nonpathogen - albumin-binding protein MA2869 1 None None None 20091898 Nonpathogen - hypothetical protein MA3080 7 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 20091992 Nonpathogen - hypothetical protein MA3174 2 None None None 20090167 Nonpathogen - hypothetical protein MA1303 1 None None None 20091147 Common - hypothetical protein MA2309 139 COG0457 NrfG, FOG: TPR repeat General function prediction only 20089341 Nonpathogen - hypothetical protein MA0450 1 None None None 20090890 Common - hypothetical protein MA2043 61 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 20093158 Common - hydrogenase membrane subunit MA4371 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 20092653 Common - hypothetical protein MA3857 30 COG1432 COG1432, Uncharacterized conserved protein Function unknown 20090454 Common - ATP-binding protein MA1596 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20092834 Common - hypothetical protein MA4041 173 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 20093286 Common pyrI aspartate carbamoyltransferase regulatory subunit MA4501 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 20089639 Nonpathogen - hypothetical protein MA0754 1 None None None 20090649 Nonpathogen - hypothetical protein MA1798 1 None None None 20089960 Nonpathogen rpl19e 50S ribosomal protein L19e MA1090 34 COG2147 RPL19A, Ribosomal protein L19E Translation, ribosomal structure and biogenesis 20089938 Common - dolichyl-phosphate beta-D-mannosyltransferase MA1068 150 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20093178 Common mtaC2 methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 2 MA4391 163 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20090900 Common - hypothetical protein MA2053 16 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 20090707 Nonpathogen - hypothetical protein MA1857 10 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20089161 Common - L-fuculose phosphate aldolase MA0263 111 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 20092778 Common - helix-turn-helix family protein MA3984 74 COG1476 COG1476, Predicted transcriptional regulators Transcription 20092805 Nonpathogen ubiA prenyltransferase MA4010 6 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 20092616 Common - hypothetical protein MA3820 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090675 Nonpathogen thyA thymidylate synthase MA1824 8 COG1810 COG1810, Uncharacterized protein conserved in archaea Function unknown 20093171 Common - hypothetical protein MA4384 164 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20090643 Common - diamine N-acetyltransferase MA1792 86 COG0456 RimI, Acetyltransferases General function prediction only 20090719 Nonpathogen - hypothetical protein MA1869 2 None None None 20092294 Nonpathogen - hypothetical protein MA3483 1 None None None 20090111 Common oppB oligopeptide ABC transporter, permease MA1247 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091025 Common rbfA glucose-1-phosphate thymidylyltransferase MA2183 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 20090928 Nonpathogen - hypothetical protein MA2083 1 None None None 20091115 Nonpathogen - hypothetical protein MA2277 6 None None None 20092583 Common gltD putative oxidoreductase MA3787 194 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 20092579 Common arsM arsenite S-adenosylmethyltransferase MA3783 205 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090899 Nonpathogen - hypothetical protein MA2052 1 COG4872 COG4872, Predicted membrane protein Function unknown 20089626 Nonpathogen - hypothetical protein MA0741 1 None None None 20089669 Nonpathogen - proteophosphoglycan MA0785 1 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 20090612 Common - surface antigen gene MA1761 76 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090192 Common - hypothetical protein MA1331 18 COG0730 COG0730, Predicted permeases General function prediction only 20090419 Nonpathogen - hypothetical protein MA1561 1 None None None 20089462 Common nirJ heme d1 biosynthesis protein NirJ MA0573 204 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20092448 Nonpathogen - hypothetical protein MA3648 2 None None None 20089290 Common cbiQ cobalt ABC transporter, permease protein MA0393 52 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20093343 Common cmtM methylcobalamin:coenzyme M methyltransferase MA4559 56 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20089731 Common mtbA methyltransferase MA0847 18 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20089464 Common nirH heme d1 biosynthesis protein NirH MA0575 58 COG1522 Lrp, Transcriptional regulators Transcription 20089033 Nonpathogen - hypothetical protein MA0134 1 None None None 20091011 Common - dolichyl-phosphate beta-D-mannosyltransferase MA2169 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20089572 Nonpathogen hdrE heterodisulfide reductase, subunit E MA0687 9 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 20089592 Common - caffeoyl-CoA O-methyltransferase MA0707 95 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 20090102 Common mop molybdenum-pterin binding protein MA1238 65 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 20090854 Nonpathogen - hypothetical protein MA2006 2 None None None 20091485 Common - hypothetical protein MA2662 3 None None None 20092912 Nonpathogen - hypothetical protein MA4119 1 COG2034 COG2034, Predicted membrane protein Function unknown 20091848 Nonpathogen - hypothetical protein MA3030 2 None None None 20089297 Common - hypothetical protein MA0402 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 20093060 Common ftsZ cell division protein FtsZ MA4271 233 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 20091168 Common - 2-heptaprenyl-1,4-naphthoquinone methyltransferase MA2333 131 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089703 Common - malate dehydrogenase MA0819 196 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 20089014 Common psd phosphatidylserine decarboxylase MA0115 92 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 20090533 Nonpathogen - hypothetical protein MA1681 1 None None None 20089171 Nonpathogen mtrB tetrahydromethanopterin S-methyltransferase subunit B MA0273 9 COG4062 MtrB, Tetrahydromethanopterin S-methyltransferase, subunit B Coenzyme metabolism 20091033 Nonpathogen - hypothetical protein MA2192 1 None None None 20090966 Nonpathogen - hypothetical protein MA2123 1 None None None 20092935 Nonpathogen - hypothetical protein MA4142 1 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 20089633 Common - Maf protein MA0748 195 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 20091960 Common - hypothetical protein MA3142 45 COG0392 COG0392, Predicted integral membrane protein Function unknown 20088926 Nonpathogen - hypothetical protein MA0027 1 None None None 20091150 Nonpathogen - hypothetical protein MA2312 1 None None None 20089709 Nonpathogen - hypothetical protein MA0825 1 None None None 20091564 Common - hypothetical protein MA2741 16 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 20090868 Nonpathogen - retroviral pol related endonuclease MA2020 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093299 Common - acetyltransferase (GNAT) family protein MA4514 95 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 20090691 Nonpathogen - hypothetical protein MA1841 1 None None None 20090070 Common - antibiotic resistance protein MA1206 36 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 20092510 Common - hypothetical protein MA3711 29 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 20089241 Nonpathogen - hypothetical protein MA0343 9 COG4827 COG4827, Predicted transporter General function prediction only 20092204 Nonpathogen - hypothetical protein MA3391 2 None None None 20091519 Common - hypothetical protein MA2695 78 COG2898 COG2898, Uncharacterized conserved protein Function unknown 20089510 Nonpathogen - hypothetical protein MA0622 8 COG4742 COG4742, Predicted transcriptional regulator Transcription 20091095 Common - sensory transduction histidine kinase MA2256 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20091222 Common - hypothetical protein MA2391 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 20089597 Nonpathogen - hypothetical protein MA0712 4 None None None 20088986 Common - DnaK protein MA0087 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 20089091 Nonpathogen - hypothetical protein MA0193 1 None None None 20091586 Common - hypothetical protein MA2763 35 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20093225 Nonpathogen - hypothetical protein MA4439 1 None None None 20090555 Common cat chloramphenicol O-acetyltransferase MA1703 22 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 20091503 Nonpathogen - hypothetical protein MA2682 1 None None None 20089199 Common oppB oligopeptide ABC transporter, permease protein MA0301 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20092567 Common - hypothetical protein MA3771 15 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090920 Common - transposase MA2074 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20089913 Common - hypothetical protein MA1041 3 None None None 20090543 Common - hypothetical protein MA1691 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 20092009 Common purF amidophosphoribosyltransferase MA3193 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 20092507 Nonpathogen - hypothetical protein MA3708 2 None None None 20090553 Common - acetyltransferase MA1701 95 COG3153 COG3153, Predicted acetyltransferase General function prediction only 20089061 Nonpathogen - hypothetical protein MA0163 6 COG4885 COG4885, Uncharacterized protein conserved in archaea Function unknown 20089248 Nonpathogen - hypothetical protein MA0350 4 None None None 20091751 Nonpathogen - hypothetical protein MA2932 1 None None None 20089566 Common mcm2 Mcm2 DNA replication licensing factor MA0681 36 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 20090518 Common nrd ribonucleotide reductase MA1665 224 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 20089776 Common pyrC dihydroorotase MA0892 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 20090400 Nonpathogen - hypothetical protein MA1542 1 None None None 20092751 Nonpathogen - hypothetical protein MA3955 1 None None None 20089715 Common - transposase MA0831 76 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089128 Nonpathogen - hypothetical protein MA0230 3 None None None 20090250 Common - holocytochrome-c synthase MA1389 10 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 20090181 Common - phosphatidylethanolamine N-methyltransferase MA1319 227 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20091982 Nonpathogen - hypothetical protein MA3164 1 None None None 20092628 Nonpathogen - hypothetical protein MA3832 1 None None None 20093413 Nonpathogen - hypothetical protein MA4634 16 COG1745 COG1745, Predicted metal-binding protein General function prediction only 20092596 Common - transposase MA3800 19 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090190 Nonpathogen - hypothetical protein MA1329 1 None None None 20091513 Common - hypothetical protein MA2690 17 COG1892 COG1892, Uncharacterized protein conserved in archaea Function unknown 20093085 Nonpathogen - hypothetical protein MA4296 1 None None None 20090233 Nonpathogen - hypothetical protein MA1372 18 COG1885 COG1885, Uncharacterized protein conserved in archaea Function unknown 20091922 Common - hypothetical protein MA3104 44 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 20092757 Nonpathogen - hypothetical protein MA3961 9 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20089533 Nonpathogen rpl44e 50S ribosomal protein L44e MA0646 33 COG1631 RPL42A, Ribosomal protein L44E Translation, ribosomal structure and biogenesis 20089140 Common - hypothetical protein MA0242 235 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 20092158 Common - bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase MA3344 204 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 20092646 Nonpathogen pfdB prefoldin, subunit beta MA3850 31 COG1382 GimC, Prefoldin, chaperonin cofactor Posttranslational modification, protein turnover, chaperones 20090146 Common - hypothetical protein MA1282 20 COG3619 COG3619, Predicted membrane protein Function unknown 20093010 Common - coenzyme F420-dependent oxidoreductase MA4220 28 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 20092200 Nonpathogen - hypothetical protein MA3386 1 None None None 20091304 Common ybtP iron ABC transporter MA2473 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 20091882 Common cheD1 chemotaxis protein CheD MA3064 85 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 20092185 Nonpathogen - hypothetical protein MA3371 1 None None None 20090176 Common - hypothetical protein MA1314 19 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20092709 Nonpathogen - hypothetical protein MA3913 1 None None None 20089481 Common serA phosphoglycerate dehydrogenase MA0592 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 20091010 Nonpathogen - hypothetical protein MA2168 1 None None None 20089746 Nonpathogen - hypothetical protein MA0862 11 COG4742 COG4742, Predicted transcriptional regulator Transcription 20091639 Common - GCN5-related N-acetyltransferase MA2815 8 COG0456 RimI, Acetyltransferases General function prediction only 20089333 Nonpathogen - hypothetical protein MA0441 9 COG5306 COG5306, Uncharacterized conserved protein Function unknown 20090199 Common - heavy-metal-associated protein MA1338 9 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 20091542 Common - cysteine desulphurase MA2718 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 20091550 Nonpathogen - hypothetical protein MA2726 1 None None None 20093288 Nonpathogen - hypothetical protein MA4503 5 None None None 20093245 Common - UTP-glucose-1-phosphate uridylyltransferase MA4459 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 20092346 Common - hypothetical protein MA3539 19 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 20091558 Common - hypothetical protein MA2734 15 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089742 Common hyuA hydantoinase MA0858 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20089501 Nonpathogen - hypothetical protein MA0612 2 None None None 20090022 Nonpathogen - hypothetical protein MA1156 1 None None None 20092143 Common - hypothetical protein MA3329 6 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 20089451 Nonpathogen - hypothetical protein MA0562 2 None None None 20091906 Nonpathogen prp1 phosphate regulatory protein homolog MA3088 26 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 20091645 Common istB IstB helper protein MA2821 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20091954 Common - peptidylprolyl isomerase MA3136 176 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 20089074 Common - transcriptional regulator, MarR family MA0176 56 COG1846 MarR, Transcriptional regulators Transcription 20090671 Common taqD glycerol-3-phosphate cytidyltransferase MA1820 151 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 20091994 Nonpathogen - hypothetical protein MA3176 3 COG0439 AccC, Biotin carboxylase Lipid metabolism 20089190 Nonpathogen srp19 signal recognition particle protein Srp19 MA0292 27 COG1400 SEC65, Signal recognition particle 19 kDa protein Intracellular trafficking and secretion 20092376 Common - acetyltransferase (GNAT) family protein MA3570 55 COG0456 RimI, Acetyltransferases General function prediction only 20092467 Nonpathogen - hypothetical protein MA3667 13 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 20093033 Common - hypothetical protein MA4243 35 COG1433 COG1433, Uncharacterized conserved protein Function unknown 20090564 Common - aspartate aminotransferase MA1712 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 20092254 Common cysE serine O-acetyltransferase MA3442 137 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 20092736 Common cadC transcriptional regulator MA3940 135 COG0640 ArsR, Predicted transcriptional regulators Transcription 20090347 Nonpathogen - hypothetical protein MA1488 21 COG1920 COG1920, Uncharacterized conserved protein Function unknown 20089874 Nonpathogen - hypothetical protein MA0998 4 None None None 20090871 Nonpathogen - hypothetical protein MA2023 1 None None None 20091781 Common - iron-sulfur cluster binding protein MA2963 139 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 20091451 Common - glycogen debranching enzyme MA2628 41 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 20092993 Common - hypothetical protein MA4202 89 COG0622 COG0622, Predicted phosphoesterase General function prediction only 20090947 Common - type I site-specific deoxyribonuclease MA2103 63 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 20089941 Nonpathogen - hypothetical protein MA1071 1 None None None 20090996 Common - periplasmic binding protein MA2153 107 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20089588 Nonpathogen - hypothetical protein MA0703 1 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 20091538 Common metA homoserine O-acetyltransferase MA2714 187 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 20092451 Nonpathogen - hypothetical protein MA3651 1 None None None 20090954 Common - multidrug ABC transporter, ATP-binding protein MA2110 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20090228 Nonpathogen - hypothetical protein MA1367 2 COG1414 IclR, Transcriptional regulator Transcription 20091264 Common - H(+)-transporting ATP synthase, subunit gamma MA2433 206 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 20092500 Common - cell surface protein MA3700 63 COG3291 COG3291, FOG: PKD repeat General function prediction only 20093094 Common - cell surface protein MA4305 91 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092391 Common - multidrug resistance efflux pump MA4663 162 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20092421 Common - hypothetical protein MA3621 57 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 20091874 Common flaI flagella accessory protein I MA3056 220 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 20089792 Common - hypothetical protein MA0914 124 COG1973 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 20090972 Nonpathogen - hypothetical protein MA2129 5 None None None 20093105 Nonpathogen - hypothetical protein MA4316 3 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20089799 Common - hypothetical protein MA0921 30 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 20090206 Common - FmtA-like protein MA1345 149 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 20092863 Nonpathogen - hypothetical protein MA4070 3 None None None 20089948 Common rps3p 30S ribosomal protein S3P MA1078 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 20090241 Common - hypothetical protein MA1380 35 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 20090354 Common fpoA F(420)H(2) dehydrogenase, subunit FpoA MA1495 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 20090297 Common - divalent cation transporter MA1437 27 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 20090654 Nonpathogen - hypothetical protein MA1803 1 None None None 20091352 Nonpathogen - hypothetical protein MA2524 1 None None None 20092890 Nonpathogen - hypothetical protein MA4097 13 COG1872 COG1872, Uncharacterized conserved protein Function unknown 20089698 Nonpathogen - hypothetical protein MA0814 2 None None None 20089021 Nonpathogen - hypothetical protein MA0122 1 None None None 20088999 Common - nucleotidyltransferase MA0100 53 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20089649 Common - hypothetical protein MA0764 23 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20090535 Common rpiA ribose 5-phosphate epimerase MA1683 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 20089150 Nonpathogen - hypothetical protein MA0252 1 None None None 20092300 Common - integral membrane protein MA3489 134 COG2962 RarD, Predicted permeases General function prediction only 20091807 Common trpD anthranilate phosphoribosyltransferase MA2989 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 20089089 Nonpathogen - hypothetical protein MA0191 9 COG4742 COG4742, Predicted transcriptional regulator Transcription 20092517 Common - hypothetical protein MA3719 3 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 20089729 Common - ABC transporter, ATP-binding protein MA0845 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20089315 Nonpathogen - hypothetical protein MA0423 1 None None None 20090004 Common hypA hydrogenase nickel incorporation protein MA1138 67 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 20089625 Nonpathogen - hypothetical protein MA0740 3 None None None 20092238 Common - hypothetical protein MA3426 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 20091077 Nonpathogen - hypothetical protein MA2237 1 None None None 20092602 Nonpathogen - hypothetical protein MA3806 1 None None None 20092216 Common - GTPase MA3404 115 COG1161 COG1161, Predicted GTPases General function prediction only 20092701 Common oppA oligopeptide ABC transporter, solute-binding protein MA3905 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20091633 Nonpathogen - hypothetical protein MA2809 1 None None None 20089614 Nonpathogen - hypothetical protein MA0729 1 None None None 20089147 Common - citrate (si)-synthase MA0249 194 COG0372 GltA, Citrate synthase Energy production and conversion 20092976 Common - reverse transcriptase MA4184 82 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20091746 Nonpathogen - hypothetical protein MA2927 1 None None None 20091219 Nonpathogen - hypothetical protein MA2388 4 None None None 20093173 Common hsp60-4 Hsp60 MA4386 244 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 20093119 Nonpathogen tbp-1 transcription factor MA4331 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 20093308 Common gatA glutamyl-tRNA (Gln) amidotransferase, subunit A MA4523 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 20090618 Common - cell surface protein MA1767 50 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092914 Nonpathogen - hypothetical protein MA4121 2 None None None 20093079 Common - hypothetical protein MA4290 15 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20091721 Nonpathogen - hypothetical protein MA2900 1 None None None 20088941 Nonpathogen erf1 peptide chain release factor 1 MA0042 34 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 20092902 Common - signal recognition particle receptor MA4109 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 20090765 Common dppA dipeptide ABC transporter, solute-binding protein MA1916 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20092166 Common - transposase MA3352 34 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093056 Nonpathogen - hypothetical protein MA4267 33 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 20089751 Common - multidrug ABC transporter, permease protein MA0867 142 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 20093182 Common hyuA hydantoinase MA4395 115 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20090399 Common - hypothetical protein MA1540 89 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20090128 Common rpoB1 DNA-directed RNA polymerase subunit B' MA1264 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 20091899 Nonpathogen flaH flagellar accessory protein FlaH MA3081 18 COG2874 FlaH, Predicted ATPases involved in biogenesis of archaeal flagella Cell motility and secretion / Intracellular trafficking and secretion 20089476 Common gltX glutamyl-tRNA synthetase MA0587 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 20091461 Common - hypothetical protein MA2638 4 None None None 20093420 Common - MotA/TolQ/ExbB proton channel family protein MA4641 21 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 20092817 Common - cobalt transport protein CbiM MA4023 65 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 20093202 Nonpathogen - 3-isopropylmalate dehydratase MA4415 33 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 20093112 Common - hypothetical protein MA4324 47 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 20089411 Common mutL DNA mismatch repair protein MA0522 192 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 20089001 Common - nucleotidyltransferase MA0102 51 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20089080 Nonpathogen eif5 translation initiation factor IF-2 subunit beta MA0182 34 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 20091251 Nonpathogen - hypothetical protein MA2420 2 None None None 20091099 Nonpathogen - hypothetical protein MA2260 3 None None None 20091628 Nonpathogen - hypothetical protein MA2806 1 None None None 20091432 Nonpathogen - hypothetical protein MA2606 1 None None None 20091778 Common - hypothetical protein MA2959 6 None None None 20092633 Nonpathogen - hypothetical protein MA3837 1 None None None 20092326 Nonpathogen - hypothetical protein MA3518 1 None None None 20088935 Nonpathogen sec11 signal sequence peptidase MA0036 17 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 20089420 Nonpathogen - hypothetical protein MA0531 2 None None None 20091157 Common - hypothetical protein MA2321 5 None None None 20091271 Common - F0F1 ATP synthase subunit epsilon MA2440 20 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 20091468 Common atsA arylsulfatase MA2645 81 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 20091708 Common - cell surface protein MA2886 63 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092094 Common pyrG CTP synthetase MA3279 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 20091313 Common - peptide ABC transporter, solute-binding protein MA2482 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20092609 Nonpathogen - hypothetical protein MA3813 1 None None None 20092044 Nonpathogen - hypothetical protein MA3228 1 None None None 20093350 Common mrpG putative monovalent cation/H+ antiporter subunit G MA4566 52 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 20091584 Common - transcriptional regulator, TetR family MA2761 56 COG1309 AcrR, Transcriptional regulator Transcription 20090059 Nonpathogen - hypothetical protein MA1193 18 COG1665 COG1665, Uncharacterized protein conserved in archaea Function unknown 20093072 Common - hypothetical protein MA4283 4 None None None 20092088 Nonpathogen - hypothetical protein MA3272 1 None None None 20090336 Common grpE heat shock protein MA1477 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 20088977 Nonpathogen - hypothetical protein MA0078 10 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 20092050 Nonpathogen - hypothetical protein MA3234 1 None None None 20089355 Common - hypothetical protein MA0464 10 COG4715 COG4715, Uncharacterized conserved protein Function unknown 20091258 Common - hypothetical protein MA2427 42 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 20091609 Common - hypothetical protein MA2786 6 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20090395 Common - ABC transporter, ATP-binding protein MA1536 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20092352 Common radA DNA repair and recombination protein RadA MA3545 68 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 20093268 Nonpathogen - retroviral pol related endonuclease MA4483 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092523 Common - hypothetical protein MA3726 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 20089900 Common - hypothetical protein MA1025 12 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20092318 Nonpathogen - hypothetical protein MA3509 2 None None None 20091682 Nonpathogen - hypothetical protein MA2858 1 None None None 20090468 Common thrC threonine synthase MA1610 227 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 161484932 Common - hypothetical protein MA4618 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 20092071 Nonpathogen - hypothetical protein MA3255 1 None None None 20093021 Nonpathogen - hypothetical protein MA4231 1 None None None 20088943 Nonpathogen - hypothetical protein MA0044 1 None None None 20089851 Nonpathogen - hypothetical protein MA0974 8 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 20089157 Nonpathogen - hypothetical protein MA0259 2 None None None 20092341 Common - methylase MA3534 153 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20089079 Common - multidrug-efflux transporter MA0181 233 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 161484942 Common thiC thiamine biosynthesis protein ThiC MA0261 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 20091329 Common fumB fumarate hydratase MA2498 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 20089227 Common - hypothetical protein MA0329 38 COG1359 COG1359, Uncharacterized conserved protein Function unknown 20089838 Nonpathogen - hypothetical protein MA0960 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 20091686 Common - glutamyl-tRNA(Gln) amidotransferase subunit E MA2862 180 COG2511 GatE, Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) Translation, ribosomal structure and biogenesis 20092688 Common - hypothetical protein MA3892 21 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 20091017 Common - membrane-bound galactosyl-transferase MA2175 87 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20091134 Nonpathogen - hypothetical protein MA2296 1 None None None 20092437 Nonpathogen - hypothetical protein MA3637 1 None None None 20091172 Common - hypothetical protein MA2337 9 COG3291 COG3291, FOG: PKD repeat General function prediction only 20091687 Nonpathogen - hypothetical protein MA2863 1 None None None 20090585 Common - hypothetical protein MA1733 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089387 Nonpathogen - hypothetical protein MA0498 1 None None None 20090103 Common - molybdenum-pterin binding protein MA1239 69 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 20089923 Common - transposase MA1052 24 None None None 20089585 Common oppB oligopeptide ABC transporter, permease protein MA0700 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091849 Common - ribonuclease Z MA3031 149 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 20089047 Nonpathogen - hypothetical protein MA0149 4 None None None 20090306 Nonpathogen - hypothetical protein MA1447 33 COG1258 COG1258, Predicted pseudouridylate synthase Translation, ribosomal structure and biogenesis 20090723 Common - hypothetical protein MA1873 163 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 20090010 Common vhtD F420-nonreducing hydrogenase II MA1144 49 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 20092825 Nonpathogen - hypothetical protein MA4032 2 None None None 20091320 Common - hypothetical protein MA2489 193 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 20091566 Common - hypothetical protein MA2743 19 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20089096 Nonpathogen - acetyltransferase (GNAT) family protein MA0198 2 COG0456 RimI, Acetyltransferases General function prediction only 20090422 Nonpathogen - hypothetical protein MA1564 1 None None None 20092400 Common cpcE phycocyanin alpha phycocyanobilin lyase MA3599 65 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 20091142 Common serC phosphoserine aminotransferase MA2304 63 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 20089656 Nonpathogen - hypothetical protein MA0772 7 COG3339 COG3339, Uncharacterized conserved protein Function unknown 20092888 Common - chlorohydrolase family protein MA4095 117 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 20090264 Nonpathogen - hypothetical protein MA1404 1 None None None 20091892 Nonpathogen - hypothetical protein MA3074 1 None None None 20090427 Common - Pap2 superfamily protein MA1569 4 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 20089651 Common - nucleotidyltransferase MA0766 24 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20089824 Nonpathogen - hypothetical protein MA0946 1 None None None 20091337 Nonpathogen - hypothetical protein MA2506 4 COG3247 HdeD, Uncharacterized conserved protein Function unknown 20093330 Nonpathogen - methyl coenzyme M reductase, subunit alpha MA4546 14 COG4058 McrA, Methyl coenzyme M reductase, alpha subunit Coenzyme metabolism 20092765 Nonpathogen rpl40e 50S ribosomal protein L40e MA3970 25 COG1552 RPL40A, Ribosomal protein L40E Translation, ribosomal structure and biogenesis 20091100 Nonpathogen - hypothetical protein MA2261 1 None None None 20089204 Common fmdA formylmethanofuran dehydrogenase, subunit A MA0306 30 COG1229 FwdA, Formylmethanofuran dehydrogenase subunit A Energy production and conversion 20090050 Common - glycosyltransferase group 2 family protein MA1184 209 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20089363 Nonpathogen - hypothetical protein MA0474 2 None None None 20089040 Nonpathogen - hypothetical protein MA0141 2 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 20091165 Nonpathogen - hypothetical protein MA2330 1 None None None 20091003 Common - hypothetical protein MA2161 14 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20091508 Common - hypothetical protein MA4679 23 COG5207 UBP14, Isopeptidase T Posttranslational modification, protein turnover, chaperones 20092716 Common - dienelactone hydrolase MA3920 16 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 20093407 Common - reverse transcriptase MA4628 77 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20093259 Common dapB dihydrodipicolinate reductase MA4474 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 20089888 Common cooC carbon-monoxide dehydrogenase accessory protein MA1013 30 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 20091621 Common - hypothetical protein MA2799 32 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20091325 Nonpathogen - hypothetical protein MA2494 4 None None None 20091203 Nonpathogen - hypothetical protein MA2371 3 None None None 20089136 Nonpathogen - hypothetical protein MA0238 9 COG1772 COG1772, Uncharacterized protein conserved in archaea Function unknown 20092784 Common - MutT related protein MA3990 73 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 20090529 Nonpathogen - hypothetical protein MA1676 2 None None None 20091404 Common - hypothetical protein MA2578 33 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090622 Common - transcriptional regulator, TetR family MA1771 44 COG1309 AcrR, Transcriptional regulator Transcription 20091520 Common - hypothetical protein MA2696 171 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 20090160 Common - hypothetical protein MA1296 53 COG2361 COG2361, Uncharacterized conserved protein Function unknown 20090218 Common - copper binding protein, plastocyanin/azurin family MA1357 37 COG3794 PetE, Plastocyanin Energy production and conversion 20090386 Common - hypothetical protein MA1527 69 None None None 20089313 Common - hypothetical protein MA0421 14 COG4902 COG4902, Uncharacterized protein conserved in archaea Function unknown 20091393 Nonpathogen - hypothetical protein MA2567 4 None None None 20090698 Common - ubiE/COQ5 methyltransferase MA1848 56 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089155 Common - transposase IS200-like protein MA0257 66 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091788 Nonpathogen - hypothetical protein MA2970 1 None None None 20090443 Nonpathogen - hypothetical protein MA1585 1 None None None 20090627 Common rrp42 exosome complex RNA-binding protein Rrp42 MA1776 140 COG2123 COG2123, RNase PH-related exoribonuclease Translation, ribosomal structure and biogenesis 20090328 Common - response regulator receiver MA1469 220 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 20090908 Common - hypothetical protein MA2061 4 None None None 20092366 Common - phosphorylase MA3560 19 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 20092952 Common atpB V-type ATP synthase subunit B MA4159 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 20089305 Common - hypothetical protein MA0412 7 None None None 20092684 Nonpathogen - hypothetical protein MA3888 1 None None None 20089981 Nonpathogen - hypothetical protein MA1115 1 None None None 20091758 Common - hypothetical protein MA2939 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 20091354 Nonpathogen - beta/gama crystallin family protein MA2526 1 None None None 20093249 Nonpathogen - retroviral pol related endonuclease MA4463 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091728 Common - transposase MA2907 108 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090157 Common - cell surface protein MA1293 50 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092283 Common - hypothetical protein MA3471 40 COG2138 COG2138, Uncharacterized conserved protein Function unknown 20089229 Common - hypothetical protein MA0331 78 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 20090782 Common - hypothetical protein MA1933 31 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 20089299 Common - hypothetical protein MA0404 97 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20090725 Nonpathogen - hypothetical protein MA1875 1 None None None 20091065 Nonpathogen - hypothetical protein MA2225 1 None None None 20092194 Nonpathogen - hypothetical protein MA3380 5 None None None 20090663 Common - hypothetical protein MA1812 25 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20089870 Common - chloride peroxidase MA0993 167 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20090790 Common - hypothetical protein MA1941 32 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 20092678 Common - multidrug efflux protein MA3882 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20090742 Common - hypothetical protein MA1892 115 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 20091481 Nonpathogen - hypothetical protein MA2658 3 None None None 20089877 Common fumC fumarate hydratase MA1001 210 COG0114 FumC, Fumarase Energy production and conversion 20091281 Common - divalent cation tolerance protein MA2450 118 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 20092534 Common cmd carboxymuconolactone decarboxylase MA3736 50 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20089338 Common - hypothetical protein MA0447 174 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 20090459 Nonpathogen - hypothetical protein MA1601 1 None None None 20089435 Nonpathogen - hypothetical protein MA0546 10 COG1326 COG1326, Uncharacterized archaeal Zn-finger protein General function prediction only 20089179 Common - sulfate/molybdate ABC transporter, permease protein MA0281 208 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 20089504 Common - transmembrane transport protein (DitE homolog) MA0615 111 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20092034 Nonpathogen - hypothetical protein MA3218 9 COG5513 COG5513, Predicted secreted protein Function unknown 20092970 Nonpathogen fmdD formylmethanofuran dehydrogenase, subunit D MA4177 15 COG1153 FwdD, Formylmethanofuran dehydrogenase subunit D Energy production and conversion 20090856 Common - sodium/calcium exchanger protein MA2008 117 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 20089568 Nonpathogen - ferredoxin MA0683 1 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 20091793 Nonpathogen - hypothetical protein MA2975 2 None None None 20089544 Common nosX membrane protein MA0657 141 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 20093133 Common - hypothetical protein MA4345 58 COG0701 COG0701, Predicted permeases General function prediction only 20091395 Nonpathogen - phosphoesterase MA2569 7 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 20089402 Common maa maltose O-acetyltransferase MA0513 127 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 20091454 Common - hypothetical protein MA2631 7 COG4894 COG4894, Uncharacterized conserved protein Function unknown 20092811 Nonpathogen - hypothetical protein MA4017 7 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 20092738 Common - hypothetical protein MA3942 67 None None None 20091448 Common - hypothetical protein MA2622 15 COG3937 COG3937, Uncharacterized conserved protein Function unknown 20092840 Common - proteinase IV MA4047 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 20089115 Common hisG ATP phosphoribosyltransferase MA0217 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 20092409 Common - hypothetical protein MA3609 157 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 20089845 Common - putative deoxyhypusine synthase MA0968 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 20089345 Nonpathogen - hypothetical protein MA0454 5 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 20092558 Common istB IstB helper protein MA3760 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20091058 Nonpathogen - hypothetical protein MA2217 6 None None None 20090710 Common isf-9 iron-sulfur flavoprotein MA1860 47 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20091376 Nonpathogen - hypothetical protein MA2549 11 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20089397 Nonpathogen - hypothetical protein MA0508 2 None None None 20091914 Common tadA2 type IV secretion system protein MA3096 150 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 20090251 Common - GTP-binding protein MA1390 228 COG1084 COG1084, Predicted GTPase General function prediction only 20092103 Common - PmbA/TldD family protein MA3288 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 20089530 Nonpathogen - H/ACA RNA-protein complex component Nop10p MA0643 24 COG2260 COG2260, Predicted Zn-ribbon RNA-binding protein Translation, ribosomal structure and biogenesis 20089969 Common - hypothetical protein MA1100 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 20091490 Common ppsA phosphoenolpyruvate synthase MA2667 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 20091533 Nonpathogen - hypothetical protein MA2709 4 None None None 20092156 Common aksA trans-homoaconitate synthase MA3342 199 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 20093067 Common - hypothetical protein MA4278 99 COG1262 COG1262, Uncharacterized conserved protein Function unknown 20092443 Common - hypothetical protein MA3643 17 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 20089800 Nonpathogen - hypothetical protein MA0922 2 None None None 20089814 Common - hypothetical protein MA0936 166 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 20090371 Nonpathogen - nucleotidyltransferase MA1512 20 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 20091860 Nonpathogen - hypothetical protein MA3042 6 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 20089762 Common - oligopeptide ABC transporter, ATP-binding protein MA0878 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 20093128 Common - biotin synthesis BioY protein MA4340 112 COG1268 BioY, Uncharacterized conserved protein General function prediction only 20090834 Common - transposase MA1986 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090025 Common - hypothetical protein MA1159 3 None None None 20089694 Common - hypothetical protein MA0810 30 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 20093240 Common - hypothetical protein MA4454 15 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20092140 Common - transposase MA3326 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090060 Common - hypothetical protein MA1194 6 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 20089826 Nonpathogen - hypothetical protein MA0948 3 None None None 20092023 Common alkA DNA-3-methyladenine glycosylase II MA3207 42 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 20089029 Common purM phosphoribosylaminoimidazole synthetase MA0130 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 20091495 Common - ATP-dependant helicase MA2672 213 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 20088911 Common cheC2 chemotaxis protein CheC MA0012 39 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 20090916 Nonpathogen - hypothetical protein MA2070 5 COG4104 COG4104, Uncharacterized conserved protein Function unknown 20092980 Nonpathogen - hypothetical protein MA4189 14 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 20089667 Common - hypothetical protein MA0783 61 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20089390 Nonpathogen - hypothetical protein MA0501 1 None None None 20092578 Common - cell surface protein MA3782 46 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20090290 Common - hypothetical protein MA1430 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20090935 Common - IstB helper protein MA2090 40 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20089753 Common cbiQ ABC transporter, permease protein MA0869 44 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20089868 Common - hypothetical protein MA0991 15 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 20093213 Nonpathogen - hypothetical protein MA4427 10 COG4827 COG4827, Predicted transporter General function prediction only 20088931 Common porA pyruvate synthase, subunit alpha MA0032 126 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 20089835 Common - hypothetical protein MA0957 57 COG5563 COG5563, Predicted integral membrane proteins containing uncharacterized repeats Function unknown 20091575 Nonpathogen - hypothetical protein MA2752 2 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 20091506 Common fabG2 3-oxoacyl-[acyl-carrier protein] reductase MA2686 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 20093200 Common hsp60-2 Hsp60 MA4413 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 20091768 Nonpathogen - hypothetical protein MA2949 3 None None None 20092135 Nonpathogen - hypothetical protein MA3321 12 COG2314 XynA, Predicted membrane protein Function unknown 20089303 Common nodL nodulation protein L MA0410 207 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 20093233 Nonpathogen - hypothetical protein MA4447 1 None None None 20092265 Common - iron ABC transporter, ATP-binding protein MA3453 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20089264 Common - hypothetical protein MA0367 28 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 20090635 Nonpathogen - 50S ribosomal protein L15e MA1784 34 COG1632 RPL15A, Ribosomal protein L15E Translation, ribosomal structure and biogenesis 20092965 Common - hypothetical protein MA4172 11 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 20093087 Nonpathogen - hypothetical protein MA4298 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 20090768 Common - adenylosuccinate synthase MA1919 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 20092117 Nonpathogen - hypothetical protein MA3302 11 COG4738 COG4738, Predicted transcriptional regulator Transcription 20090902 Common - MarR family protein MA2055 43 COG1846 MarR, Transcriptional regulators Transcription 20091738 Nonpathogen - hypothetical protein MA2918 3 None None None 20092414 Common - hypothetical protein MA3614 29 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 20089385 Nonpathogen - hypothetical protein MA0496 1 None None None 20092957 Common - corrinoid protein MA4164 169 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20091929 Nonpathogen - hypothetical protein MA3111 1 None None None 20089535 Nonpathogen - DNA primase small subunit MA0648 32 COG1467 PRI1, Eukaryotic-type DNA primase, catalytic (small) subunit DNA replication, recombination, and repair 20091194 Nonpathogen - hypothetical protein MA2361 1 None None None 20091477 Nonpathogen - hypothetical protein MA2654 1 None None None 20090838 Nonpathogen - hypothetical protein MA1990 1 None None None 20091031 Nonpathogen - hypothetical protein MA2190 5 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20090098 Common - iron(III) ABC transporter, permease protein MA1234 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20090138 Common - sensory transduction histidine kinase MA1274 182 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20093386 Common fwdE formylmethanofuran dehydrogenase, subunit E MA4602 39 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 20089664 Common - integral membrane protein MA0780 106 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 20091235 Common - hypothetical protein MA2404 23 COG3372 COG3372, Uncharacterized conserved protein Function unknown 20091695 Nonpathogen - hypothetical protein MA2873 3 None None None 20090312 Nonpathogen - hypothetical protein MA1453 1 None None None 20091436 Nonpathogen - hypothetical protein MA2610 1 None None None 20093167 Common - hypothetical protein MA4380 37 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 20093298 Nonpathogen - hypothetical protein MA4513 28 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 20090717 Nonpathogen - hypothetical protein MA1867 2 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 20091205 Common - hypothetical protein MA2373 32 None None None 20093176 Common cobW cobalamin biosynthesis protein MA4389 107 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 20090527 Common - hypothetical protein MA1674 206 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 20093370 Nonpathogen - hypothetical protein MA4586 1 None None None 20088928 Nonpathogen - hypothetical protein MA0029 4 None None None 20092428 Nonpathogen - nitrogenase-related protein MA3628 29 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20093046 Nonpathogen - hypothetical protein MA4256 2 None None None 20089375 Common - hypothetical protein MA0486 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 20091149 Nonpathogen - hypothetical protein MA2311 8 COG4079 COG4079, Uncharacterized protein conserved in archaea Function unknown 20092742 Nonpathogen cmd carboxymuconolactone decarboxylase MA3946 8 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20089289 Nonpathogen - hypothetical protein MA0392 1 None None None 20089521 Common - hypothetical protein MA0634 91 COG1738 COG1738, Uncharacterized conserved protein Function unknown 20091389 Common - hypothetical protein MA2563 7 COG5240 SEC21, Vesicle coat complex COPI, gamma subunit Intracellular trafficking and secretion 20090279 Common - cobalt transport protein MA1419 64 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20090647 Nonpathogen - hypothetical protein MA1796 3 None None None 20092664 Common - glycosyltransferase MA3868 184 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20092476 Common - ABC transporter, ATP-binding protein MA3676 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 20089705 Common - hypothetical protein MA0821 19 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 20089031 Common - cofactor-independent phosphoglycerate mutase MA0132 59 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 20092406 Common ack acetate kinase MA3606 162 COG0282 ackA, Acetate kinase Energy production and conversion 20089370 Nonpathogen - hypothetical protein MA0481 2 None None None 20089076 Common - transcriptional regulator, TetR family MA0178 86 COG1309 AcrR, Transcriptional regulator Transcription 20092012 Nonpathogen - hypothetical protein MA3196 1 None None None 20092910 Nonpathogen - 30S ribosomal protein S19e MA4117 34 COG2238 RPS19A, Ribosomal protein S19E (S16A) Translation, ribosomal structure and biogenesis 20090892 Common - hypothetical protein MA2045 83 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 20093345 Common - sensory transduction histidine kinase MA4561 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20092462 Common - hypothetical protein MA3662 97 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20092296 Common - mttA/Hcf106 protein MA3485 53 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 20089245 Nonpathogen - hypothetical protein MA0347 1 None None None 20092179 Common - hypothetical protein MA3365 6 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 20090645 Common - metallo-beta-lactamase MA1794 212 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 20090905 Common - hypothetical protein MA2058 189 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20092170 Nonpathogen - hypothetical protein MA3356 1 None None None 20090272 Nonpathogen - hypothetical protein MA1412 3 None None None 20089184 Common - hypothetical protein MA0286 109 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 20089195 Common - ubiE/COQ5 methyltransferase MA0297 176 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092655 Common - rhomboid protein MA3859 171 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 20092718 Common - periplasmic binding protein MA3922 132 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091166 Nonpathogen - hypothetical protein MA2331 2 None None None 20089466 Common hemA glutamyl-tRNA reductase MA0577 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 20091798 Nonpathogen - hypothetical protein MA2980 2 None None None 20090606 Common - cell surface protein MA1754 70 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092610 Nonpathogen - hypothetical protein MA3814 1 None None None 20088908 Nonpathogen - hypothetical protein MA0009 5 None None None 20090960 Nonpathogen - hypothetical protein MA2117 1 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 20090922 Common - hypothetical protein MA2076 31 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 20091137 Nonpathogen - hypothetical protein MA2299 1 None None None 20090194 Nonpathogen - hypothetical protein MA1333 1 None None None 20091749 Nonpathogen - hypothetical protein MA2930 1 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 20091013 Common cps capsular polysaccharide biosynthesis protein MA2171 15 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 20089551 Common nqr6 ferredoxin MA0664 60 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 20089292 Nonpathogen - hypothetical protein MA0396 1 None None None 20091027 Common - dTDP-glucose 4,6-dehydratase MA2186 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 20093080 Common - cell surface protein MA4291 102 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089739 Common mtaA methylcobalamin:coenzyme M methyltransferase MA0855 36 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20092545 Common - hypothetical protein MA3747 60 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 20092836 Common - hypothetical protein MA4043 63 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 20092586 Common ilvC ketol-acid reductoisomerase MA3790 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 20092807 Common purH phosphoribosylaminoimidazolecarboxamide formyltransferase MA4012 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 20091483 Nonpathogen - hypothetical protein MA2660 8 None None None 20089637 Common - hypothetical protein MA0752 176 COG1750 COG1750, Archaeal serine proteases General function prediction only 20091667 Common - hypothetical protein MA2843 117 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 20093273 Nonpathogen - hypothetical protein MA4488 1 None None None 20089012 Common - ADP-ribose pyrophosphatase MA0113 166 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 161484944 Common pylS pyrolysyl-tRNA synthetase MA0155 10 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 20088973 Common radB DNA repair and recombination protein RadB MA0074 200 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 20090471 Common - TPR-domain containing protein MA1613 184 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 20091671 Common - hypothetical protein MA2846 73 COG0628 PerM, Predicted permease General function prediction only 20089343 Common - glycosyltransferase MA0452 38 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 20091523 Common - flavodoxin MA2699 104 COG0716 FldA, Flavodoxins Energy production and conversion 20092933 Nonpathogen - hypothetical protein MA4140 1 None None None 20089164 Common - hypothetical protein MA0266 120 COG1690 RtcB, Uncharacterized conserved protein Function unknown 20090073 Nonpathogen anfG nitrogenase, subunit delta MA1209 5 None None None 20090054 Nonpathogen - hypothetical protein MA1188 1 None None None 20089519 Common groEL chaperonin GroEL MA0631 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 20091761 Common - transposase MA2942 22 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20089599 Common - hypothetical protein MA0714 43 COG0391 COG0391, Uncharacterized conserved protein Function unknown 20091309 Common - peptide ABC transporter, ATP-binding protein MA2478 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20090478 Common - hypothetical protein MA1623 34 COG1865 COG1865, Uncharacterized conserved protein Function unknown 20092561 Nonpathogen - hypothetical protein MA3763 1 None None None 20089211 Nonpathogen - hypothetical protein MA0313 6 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 20093377 Common aroD 3-dehydroquinate dehydratase MA4593 57 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 20091249 Common hsdR type I site-specific deoxyribonuclease protein R MA2418 126 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 20089276 Common eif2B2 translation initiation factor IF-2B subunit delta MA0379 132 COG1184 GCD2, Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 20091047 Common - transcription repressor MA2206 89 COG1846 MarR, Transcriptional regulators Transcription 20092092 Nonpathogen - hypothetical protein MA3277 1 None None None 20091369 Nonpathogen - hypothetical protein MA2542 1 None None None 20089784 Common - glycogen debranching enzyme-related protein (4-alpha-glucanotransferase) MA0905 48 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 20090845 Common - hypothetical protein MA1997 7 None None None 20091241 Common pfl formate acetyltransferase activating enzyme MA2410 38 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 20093143 Common isf-19 iron-sulfur flavoprotein MA4356 41 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20090578 Common iorB indolepyruvate oxidoreductase subunit B MA1726 88 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 20091343 Common - mRNA 3-end processing factor MA2513 139 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 20090759 Common dppE dipeptide ABC transporter, ATP-binding protein MA1910 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20093160 Common - hydrogenase-3, subunit G (HycG homolog) MA4373 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 20090380 Nonpathogen rpl7ae 50S ribosomal protein L7Ae MA1521 37 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 20091380 Common - sensory transduction histidine kinase MA2553 222 COG3322 COG3322, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 20091020 Common - LPS biosynthesis protein MA2178 201 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20093396 Common leuA 2-isopropylmalate synthase MA4615 221 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 20089559 Common pycB pyruvate carboxylase subunit B MA0674 162 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 20091347 Common - hypothetical protein MA2519 2 None None None 20089898 Common - indolepyruvate oxidoreductase subunit B MA1023 104 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 20090367 Common - cell surface protein MA1508 41 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20090887 Nonpathogen - hypothetical protein MA2040 4 None None None 20092711 Common - ubiE/COQ5 methyltransferase MA3915 158 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090032 Nonpathogen - hypothetical protein MA1166 2 None None None 20091252 Nonpathogen - hypothetical protein MA2421 4 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 20091946 Nonpathogen hdrA heterodisulfide reductase, subunit A MA3128 36 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 20092979 Common - hypothetical protein MA4188 42 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092304 Common - Hnh endonuclease MA3494 23 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 20092695 Common nifK nitrogenase, subunit beta MA3899 59 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20090109 Common oppD oligopeptide ABC transporter, ATP-binding protein MA1245 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091398 Common - homoserine dehydrogenase MA2572 218 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 20090678 Common - hypothetical protein MA1827 213 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20091117 Common brkB ribonuclease RN MA2279 66 COG1295 Rbn, Predicted membrane protein Function unknown 20092453 Nonpathogen - hypothetical protein MA3653 1 None None None 20090804 Common pheT phenylalanyl-tRNA synthetase subunit beta MA1956 243 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 20089328 Common - hypothetical protein MA0436 27 COG2516 COG2516, Biotin synthase-related enzyme General function prediction only 20091618 Nonpathogen - hypothetical protein MA2795 1 None None None 20092015 Nonpathogen - hypothetical protein MA3199 3 None None None 20091660 Nonpathogen - transposase MA2836 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091637 Common slyD peptidylprolyl isomerase MA2813 108 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 20093257 Nonpathogen rps17E 30S ribosomal protein S17e MA4472 33 COG1383 RPS17A, Ribosomal protein S17E Translation, ribosomal structure and biogenesis 20089973 Common cmk cytidylate kinase MA1104 38 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 20091154 Nonpathogen - hypothetical protein MA2318 1 None None None 20092771 Nonpathogen - hypothetical protein MA3977 1 None None None 20093337 Nonpathogen - hypothetical protein MA4553 1 None None None 20091336 Nonpathogen - hypothetical protein MA2505 1 None None None 20091229 Common - hypothetical protein MA2398 156 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 20091466 Nonpathogen - hypothetical protein MA2643 1 None None None 20088959 Nonpathogen - hypothetical protein MA0060 1 None None None 20092905 Nonpathogen eif6 translation initiation factor IF-6 MA4112 33 COG1976 TIF6, Translation initiation factor 6 (eIF-6) Translation, ribosomal structure and biogenesis 20089173 Nonpathogen mtrD tetrahydromethanopterin S-methyltransferase subunit D MA0275 14 COG4060 MtrD, Tetrahydromethanopterin S-methyltransferase, subunit D Coenzyme metabolism 20091424 Nonpathogen - hypothetical protein MA2598 1 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 20091742 Common - hypothetical protein MA2922 41 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 20091364 Common cam carbonate dehydratase MA2536 167 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 20090967 Nonpathogen - hypothetical protein MA2124 1 None None None 20091611 Nonpathogen - hypothetical protein MA2788 1 None None None 20091291 Nonpathogen - hypothetical protein MA2460 1 None None None 20091969 Common - hypothetical protein MA3151 37 COG1378 COG1378, Predicted transcriptional regulators Transcription 20091675 Common - putative thiazole biosynthetic enzyme MA2851 32 COG1635 THI4, Flavoprotein involved in thiazole biosynthesis Coenzyme metabolism 20089683 Nonpathogen - hypothetical protein MA0799 13 COG0392 COG0392, Predicted integral membrane protein Function unknown 20092734 Common - hypothetical protein MA3938 68 None None None 20092795 Nonpathogen - hypothetical protein MA4000 15 COG3389 COG3389, Uncharacterized protein conserved in archaea Function unknown 20089744 Nonpathogen - hypothetical protein MA0860 1 None None None 20091952 Nonpathogen - hypothetical protein MA3134 6 COG3247 HdeD, Uncharacterized conserved protein Function unknown 20092122 Common pyrE orotate phosphoribosyltransferase MA3307 234 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 20090508 Common - hypothetical protein MA1655 19 COG0778 NfnB, Nitroreductase Energy production and conversion 20090583 Nonpathogen - hypothetical protein MA1731 2 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 20090269 Common - 5-methylthioadenosine phosphorylase MA1409 168 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 20090592 Nonpathogen - hypothetical protein MA1740 8 COG2892 COG2892, Uncharacterized protein conserved in archaea Function unknown 20092065 Nonpathogen - hypothetical protein MA3249 1 None None None 20089925 Nonpathogen - hypothetical protein MA1054 8 COG4906 COG4906, Predicted membrane protein Function unknown 20092256 Nonpathogen - hypothetical protein MA3444 1 None None None 20092075 Common - serine/threonine specific protein phosphatase MA3259 22 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 20093363 Nonpathogen - hypothetical protein MA4579 1 None None None 20089911 Nonpathogen - hypothetical protein MA1039 1 None None None 20092085 Nonpathogen - peptidyl-tRNA hydrolase MA3269 34 COG1990 COG1990, Uncharacterized conserved protein Function unknown 20092598 Nonpathogen - hypothetical protein MA3802 1 None None None 20090262 Nonpathogen - hypothetical protein MA1402 1 None None None 20091021 Nonpathogen - hypothetical protein MA2179 3 None None None 20089994 Common - ABC transporter, solute-binding protein MA1128 59 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20092919 Common - hypothetical protein MA4126 17 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 20089549 Common nqr4 SoxR-reducing system protein RsxE MA0662 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 20090462 Common - hypothetical protein MA1604 2 None None None 20090597 Nonpathogen - hypothetical protein MA1745 1 None None None 20092879 Nonpathogen moaD molybdopterin converting factor, subunit 1 MA4086 9 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 20092543 Common - hypothetical protein MA3745 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20091990 Nonpathogen - hypothetical protein MA3172 8 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20093035 Common - hypothetical protein MA4245 33 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 20090566 Common - aldehyde ferredoxin oxidoreductase MA1714 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 20092465 Common - hypothetical protein MA3665 115 COG1203 COG1203, Predicted helicases General function prediction only 20090568 Common - hypothetical protein MA1716 29 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 20089621 Nonpathogen - hypothetical protein MA0736 2 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 20091070 Nonpathogen - hypothetical protein MA2230 1 None None None 20091595 Common - iron(III) ABC transporter, solute-binding protein MA2772 86 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20093275 Nonpathogen - hypothetical protein MA4490 2 None None None 20089577 Common - geranylgeranyl reductase MA0692 102 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20092235 Common - hypothetical protein MA3423 15 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20090814 Common asn asparagine synthase (glutamine-hydrolyzing) MA1966 200 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 20089866 Common - transcriptional regulator, MerR family MA0989 55 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 20091872 Nonpathogen - hypothetical protein MA3054 2 None None None 20090974 Common - nucleotidyltransferase MA2131 50 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20088921 Common - iron dependent repressor MA0022 80 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 20092222 Common - hypothetical protein MA3410 16 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 20089453 Common - hypothetical protein MA0564 6 None None None 20088997 Nonpathogen - hypothetical protein MA0098 2 None None None 20090226 Nonpathogen - hypothetical protein MA1365 1 None None None 20090439 Common - hypothetical protein MA1581 52 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 20090739 Nonpathogen - hypothetical protein MA1889 1 None None None 20089045 Common - NADPH:quinone reductase MA0147 74 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 20090295 Common - potassium channel protein MA1435 19 COG3273 COG3273, Uncharacterized conserved protein Function unknown 20092723 Nonpathogen - hypothetical protein MA3927 3 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 20093107 Common - hypothetical protein MA4318 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 20090826 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B/molybdopterin converting factor, large subunit MA1978 168 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 20090162 Nonpathogen - hypothetical protein MA1298 7 None None None 20091744 Common mauG methylamine metabolism protein MA2925 56 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 20093328 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase MA4544 233 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 20091040 Common - hypothetical protein MA2199 31 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 20089797 Common - orotate phosphoribosyltransferase MA0919 118 COG0856 COG0856, Orotate phosphoribosyltransferase homologs Nucleotide transport and metabolism 20090188 Nonpathogen - hypothetical protein MA1327 2 COG3462 COG3462, Predicted membrane protein Function unknown 20089804 Nonpathogen - hypothetical protein MA0926 11 COG3355 COG3355, Predicted transcriptional regulator Transcription 20092302 Common - hypothetical protein MA3492 22 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 20090537 Common - hypothetical protein MA1685 27 COG3794 PetE, Plastocyanin Energy production and conversion 20091773 Common - transposase MA2954 37 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091075 Common - hypothetical protein MA2235 22 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 20091635 Common ssrA site-specific recombinase MA2811 153 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20089946 Common rps19p 30S ribosomal protein S19P MA1076 247 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 20092873 Nonpathogen - hypothetical protein MA4080 1 None None None 20090208 Common - ubiE/COQ5 methyltransferase MA1347 188 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092945 Common atpH H(+)-transporting ATP synthase, subunit H MA4152 18 COG2811 NtpF, Archaeal/vacuolar-type H+-ATPase subunit H Energy production and conversion 20089495 Common idsA bifunctional short chain isoprenyl diphosphate synthase MA0606 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 20090894 Common - hypothetical protein MA2047 3 None None None 20091599 Common - iron(III) ABC transporter, ATP-binding protein MA2776 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20091358 Nonpathogen - hypothetical protein MA2530 1 None None None 20093421 Common - hypothetical protein MA4642 13 COG4744 COG4744, Uncharacterized conserved protein Function unknown 20091208 Common - nucleotidyltransferase MA2376 51 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20089512 Common - hypothetical protein MA0624 33 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 20092229 Nonpathogen - hypothetical protein MA3417 1 None None None 20092172 Common - iron(III) ABC transporter, ATP-binding protein MA3358 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20090866 Nonpathogen - hypothetical protein MA2018 1 None None None 20091669 Common - hypothetical protein MA2845 11 COG5426 COG5426, Uncharacterized membrane protein Function unknown 20090763 Common dppA dipeptide ABC transporter, solute-binding protein MA1914 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20091037 Nonpathogen - hypothetical protein MA2196 1 None None None 20090042 Common - polysaccharide ABC transporter, permease protein MA1176 121 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 20090829 Nonpathogen - hypothetical protein MA1981 14 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 20093048 Common cbiC precorrin-8X methylmutase MA4258 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 20092924 Nonpathogen - hypothetical protein MA4131 1 None None None 20090082 Common vnfK nitrogenase, subunit beta MA1218 53 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20089416 Common mtbC dimethylamine corrinoid protein MA0527 170 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20090049 Common - 1,2-diacylglycerol 3-glucosyltransferase MA1183 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 161484934 Common - hypothetical protein MA2756 187 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20090100 Common modB molybdate ABC transporter, permease protein MA1236 235 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 20091654 Nonpathogen - hypothetical protein MA2830 1 None None None 20089429 Nonpathogen - hypothetical protein MA0540 15 COG1694 MazG, Predicted pyrophosphatase General function prediction only 20092245 Common istB IstB helper protein MA3433 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090864 Nonpathogen - hypothetical protein MA2016 10 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 20089971 Common - hypothetical protein MA1102 82 COG1262 COG1262, Uncharacterized conserved protein Function unknown 20091097 Common - hypothetical protein MA2258 49 COG1801 COG1801, Uncharacterized conserved protein Function unknown 20091941 Common istB IstB helper protein MA3123 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20091856 Common - hypothetical protein MA3038 12 None None None 20089720 Common - transposase MA0836 43 None None None 20089093 Common - hypothetical protein MA0195 41 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 20089576 Common - geranylgeranyl reductase MA0691 97 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20093004 Common - benzodiazepine receptor TspO MA4214 60 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 20091220 Nonpathogen - hypothetical protein MA2389 8 None None None 20091844 Nonpathogen - hypothetical protein MA3026 3 None None None 20092309 Nonpathogen - hypothetical protein MA3499 1 None None None 20090730 Common - hypothetical protein MA1880 16 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20090034 Common moaC putative molybdenum cofactor biosynthesis protein C MA1168 196 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 20092505 Common gcp O-sialoglycoprotein endopeptidase/protein kinase MA3705 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 20090332 Common - amino acid kinase MA1473 23 COG2054 COG2054, Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases General function prediction only 20092560 Nonpathogen - hypothetical protein MA3762 1 None None None 20089478 Nonpathogen - hypothetical protein MA0589 1 None None None 20089321 Common - hypothetical protein MA0429 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 20089696 Nonpathogen - hypothetical protein MA0812 1 None None None 20092753 Common - ABC transporter, ATP-binding protein MA3957 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20089422 Common - hypothetical protein MA0533 11 COG3212 COG3212, Predicted membrane protein Function unknown 20089488 Nonpathogen rpoK DNA-directed RNA polymerase, subunit K MA0599 29 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 20090183 Common - sensory transduction histidine kinase MA1322 181 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090843 Nonpathogen - hypothetical protein MA1995 3 COG0439 AccC, Biotin carboxylase Lipid metabolism 20092374 Common - hypothetical protein MA3568 11 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 20089101 Common - signal-transducing histidine kinase MA0203 192 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20091705 Common - hypothetical protein MA2883 9 None None None 20092868 Common - transcriptional regulator, CopG family MA4075 66 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 20090541 Nonpathogen - hypothetical protein MA1689 2 None None None 20089243 Common - hypothetical protein MA0345 14 COG4744 COG4744, Uncharacterized conserved protein Function unknown 20092344 Nonpathogen - hypothetical protein MA3537 5 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 20093017 Common - transposase MA4227 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092426 Common cbiA2 cobyrinic acid a,c-diamide synthase MA3626 137 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 20089413 Nonpathogen - hypothetical protein MA0524 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 20093247 Common - polysaccharide biosynthesis protein MA4461 163 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 20092495 Nonpathogen rps24e 30S ribosomal protein S24e MA3695 32 COG2004 RPS24A, Ribosomal protein S24E Translation, ribosomal structure and biogenesis 20091984 Common - hypothetical protein MA3166 114 COG1733 COG1733, Predicted transcriptional regulators Transcription 20092755 Common - ABC transporter, permease protein MA3959 185 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 20089760 Nonpathogen - hypothetical protein MA0876 3 None None None 20089331 Common - fructose-bisphosphate aldolase MA0439 97 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 20091568 Common - hypothetical protein MA2745 35 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20093415 Common ndh NADH dehydrogenase MA4636 193 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 20092298 Common tatC translocase protein MA4666 202 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 20090065 Common - iron ABC transporter, permease protein MA1199 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20092707 Nonpathogen - hypothetical protein MA3911 1 None None None 20089885 Common - transposase MA1009 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091556 Common - sensory transduction histidine kinase MA2732 123 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089294 Nonpathogen - retroviral pol related endonuclease MA0399 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092740 Common - universal stress protein MA3944 52 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20091544 Common cysK cysteine synthase MA2720 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 20089717 Common fwdA formylmethanofuran dehydrogenase, subunit A MA0833 24 COG1229 FwdA, Formylmethanofuran dehydrogenase subunit A Energy production and conversion 20092379 Common - transposase MA3575 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090174 Common - hypothetical protein MA1312 28 COG3875 COG3875, Uncharacterized conserved protein Function unknown 20089655 Common - NADPH:quinone reductase MA0771 191 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 20089740 Common - hypothetical protein MA0856 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 20090349 Common - FO synthase subunit 2 MA1490 82 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 20091588 Common - hypothetical protein MA2765 33 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20091515 Common - protease MA4661 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 20091546 Common thiE thiamine-phosphate pyrophosphorylase MA2722 207 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 20092626 Nonpathogen - hypothetical protein MA3830 1 None None None 20092876 Common - NaH antiporter protein MA4083 200 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 20089670 Nonpathogen - hypothetical protein MA0786 1 None None None 20091535 Common - hypothetical protein MA2711 11 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 20089192 Nonpathogen - hypothetical protein MA0294 3 None None None 20091643 Nonpathogen - hypothetical protein MA2819 3 None None None 20090918 Common - hypothetical protein MA2072 14 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091322 Nonpathogen - hypothetical protein MA2491 2 None None None 20092858 Common phnP ATP-binding protein PhnP MA4065 106 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 20091327 Nonpathogen - hypothetical protein MA2496 7 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 20090704 Common - hypothetical protein MA1854 25 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 20091684 Common aldH aldehyde dehydrogenase (NAD+) MA2860 223 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 20092183 Nonpathogen - hypothetical protein MA3369 1 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 20091973 Common - hypothetical protein MA3155 16 None None None 20092059 Common - integral membrane protein MA3243 140 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 20091227 Nonpathogen - hypothetical protein MA2396 1 None None None 20090019 Common - 2-methylthioadenine synthase MA1153 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 20092827 Common - hypothetical protein MA4034 55 COG5276 COG5276, Uncharacterized conserved protein Function unknown 20092129 Nonpathogen - hypothetical protein MA3315 2 None None None 20091651 Common - metal-dependent phosphohydrolase MA2827 9 None None None 20092333 Nonpathogen - hypothetical protein MA3525 33 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 20091266 Common - H(+)-transporting ATP synthase, subunit B MA2435 30 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 20091999 Common - integral membrane protein MA3181 81 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 20093261 Nonpathogen - hypothetical protein MA4476 3 None None None 20089513 Nonpathogen - hypothetical protein MA0625 1 None None None 20090420 Common - hypothetical protein MA1562 5 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 20090425 Common pyrOA pyridoxine biosynthesis protein MA1567 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 20093012 Common - cell surface protein MA4222 20 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 161484940 Common rpl13p 50S ribosomal protein L13P MA0596 187 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 20091577 Nonpathogen - hypothetical protein MA2754 3 None None None 20092521 Nonpathogen - hypothetical protein MA3724 1 None None None 20092073 Nonpathogen - hypothetical protein MA3257 3 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20092648 Common - transposase MA3852 41 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091163 Common - hypothetical protein MA2328 6 None None None 20088962 Common ssuB sulfonate ABC transporter, ATP-binding protein MA0063 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 20093059 Nonpathogen - hypothetical protein MA4270 1 None None None 20093405 Nonpathogen - hypothetical protein MA4624 1 None None None 20090941 Common - hypothetical protein MA2096 18 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 20092782 Common - transposase MA3988 68 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092604 Nonpathogen - hypothetical protein MA3808 1 None None None 20092909 Nonpathogen - hypothetical protein MA4116 33 COG2118 COG2118, DNA-binding protein General function prediction only 20090089 Common nifV homocitrate synthase MA1225 208 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 20092529 Common fpoF F420H2 dehydrogenase subunit F MA3732 40 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 20089361 Common - hypothetical protein MA0472 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092686 Common pyk pyruvate kinase MA3890 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 20091818 Nonpathogen - hypothetical protein MA3000 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 20093153 Common - ABC transporter, ATP-binding protein MA4366 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 20091771 Common - hypothetical protein MA2952 36 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20089134 Common - NifS protein MA0236 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 20089931 Common - polysaccharide biosynthesis protein MA1061 87 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20090384 Common infB translation initiation factor IF-2 MA1525 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 20091935 Nonpathogen - hypothetical protein MA3117 2 None None None 20092209 Nonpathogen - hypothetical protein MA3397 4 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090799 Common - hypothetical protein MA1951 96 COG1262 COG1262, Uncharacterized conserved protein Function unknown 20091894 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta MA3076 112 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 20092781 Nonpathogen eif5A translation initiation factor IF-5A MA3987 34 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 20091144 Nonpathogen - hypothetical protein MA2306 1 None None None 20093332 Nonpathogen - methyl coenzyme M reductase, subunit D MA4548 14 COG4056 McrC, Methyl coenzyme M reductase, subunit C Coenzyme metabolism 20091886 Common cheY1 chemotaxis response regulator MA3068 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 20092354 Nonpathogen - hypothetical protein MA3547 6 None None None 20091278 Common - potassium channel protein MA2447 112 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 20092988 Common - hypothetical protein MA4197 94 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 20092900 Common - hypothetical protein MA4107 19 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20093070 Nonpathogen - hypothetical protein MA4281 2 None None None 20090753 Common - hypothetical protein MA1904 156 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20092202 Common - serine protease inhibitor MA3388 29 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 20091884 Common cheA1 chemotaxis sensor histidine kinase MA3066 149 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 20090551 Common - hypothetical protein MA1699 47 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20089311 Common isf-4 iron-sulfur flavoprotein MA0418 51 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20090126 Common rpoA2 DNA-directed RNA polymerase subunit A'' MA1262 214 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 20093054 Common - isocitrate/isopropylmalate dehydrogenase family protein MA4265 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 20091366 Nonpathogen - hypothetical protein MA2538 1 None None None 20093114 Common - hypothetical protein MA4326 16 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 20092885 Common ribD hypothetical protein MA4092 212 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 20093231 Nonpathogen - hypothetical protein MA4445 7 None None None 20090278 Common - hypothetical protein MA1418 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20092145 Nonpathogen - hypothetical protein MA3331 1 None None None 20093180 Common - GPR1/FUN34/yaaH family protein MA4393 53 COG1584 COG1584, Predicted membrane protein Function unknown 20093077 Nonpathogen - hypothetical protein MA4288 1 None None None 20091501 Common - transposase MA2680 48 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089357 Nonpathogen - hypothetical protein MA0468 1 None None None 20090305 Nonpathogen - 50S ribosomal protein L21e MA1446 34 COG2139 RPL21A, Ribosomal protein L21E Translation, ribosomal structure and biogenesis 20092396 Common - hypothetical protein MA3595 37 COG1146 COG1146, Ferredoxin Energy production and conversion 20091805 Common trpE anthranilate synthase component I MA2987 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 20090641 Common thiC thiamine biosynthesis protein ThiC MA1790 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 20092316 Common - transposase MA3506 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089236 Nonpathogen - hypothetical protein MA0338 3 None None None 20091570 Nonpathogen - hypothetical protein MA2747 1 None None None 20093038 Common - phosphatidylethanolamine N-methyltransferase MA4248 211 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089142 Common - hypothetical protein MA0244 38 COG1786 COG1786, Uncharacterized conserved protein Function unknown 20091603 Common - hypothetical protein MA2780 36 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 20090393 Common - transposase MA1534 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093009 Common - hypothetical protein MA4219 47 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 20090169 Common - nucleotidyltransferase MA1305 44 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20093323 Nonpathogen - hypothetical protein MA4538 1 None None None 20088945 Nonpathogen - hypothetical protein MA0046 2 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 20089149 Nonpathogen - hypothetical protein MA0251 2 COG1470 COG1470, Predicted membrane protein Function unknown 20090998 Common - hypothetical protein MA2155 195 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089274 Common - ABC transporter, ATP-binding protein MA0377 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20092052 Nonpathogen - hypothetical protein MA3236 3 None None None 20093418 Nonpathogen - hypothetical protein MA4639 1 None None None 20090949 Common - StySKI methylase MA2105 21 None None None 20091103 Common - hypothetical protein MA2265 4 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 20089643 Common - sensory transduction histidine kinase MA0758 180 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090057 Common - acetyltransferase (GNAT) family protein MA1191 29 COG0456 RimI, Acetyltransferases General function prediction only 20090397 Common - hypothetical protein MA1538 22 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20088970 Common - radical activating enzyme MA0071 73 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 20089902 Nonpathogen - hypothetical protein MA1027 10 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20093352 Common mrpE putative monovalent cation/H+ antiporter subunit E MA4568 5 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 20089882 Common cydA cytochrome d ubiquinol oxidase, subunit I MA1006 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 20088979 Common - hypothetical protein MA0080 38 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 20089953 Nonpathogen rpl24p 50S ribosomal protein L24P MA1083 34 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 20090611 Common - hypothetical protein MA1760 7 COG1572 COG1572, Uncharacterized conserved protein Function unknown 20090876 Common istB IstB helper protein MA2028 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20093238 Common - glycosyltransferase (group I) MA4452 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20090879 Nonpathogen - hypothetical protein MA2031 1 None None None 20092854 Nonpathogen - hypothetical protein MA4061 32 COG1602 COG1602, Uncharacterized conserved protein Function unknown 20092168 Common - transposase MA3354 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093354 Common mrpC putative monovalent cation/H+ antiporter subunit C MA4570 98 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 20090483 Common - sensory transduction histidine kinase MA1628 180 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092388 Nonpathogen - hypothetical protein MA3584 12 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20091911 Common pstS phosphate ABC transporter, solute-binding protein MA3093 24 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 20090434 Nonpathogen - hypothetical protein MA1576 1 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 20092830 Nonpathogen - hypothetical protein MA4037 2 None None None 20092176 Common - hypothetical protein MA3362 45 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 161484931 Nonpathogen - hypothetical protein MA4660 35 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 20090781 Nonpathogen - hypothetical protein MA1932 1 None None None 20091795 Nonpathogen - hypothetical protein MA2977 1 None None None 20090365 Common fpoN F(420)H(2) dehydrogenase, subunit FpoN MA1506 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 20090914 Nonpathogen - hypothetical protein MA2067 1 None None None 20091049 Common - protein export membrane protein MA2208 98 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 20091386 Common - hypothetical protein MA2559 63 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 20093082 Nonpathogen - hypothetical protein MA4293 4 COG3291 COG3291, FOG: PKD repeat General function prediction only 20091832 Nonpathogen - hypothetical protein MA3014 10 COG4860 COG4860, Uncharacterized protein conserved in archaea Function unknown 20089447 Common - hypothetical protein MA0558 7 None None None 20091224 Nonpathogen - hypothetical protein MA2393 1 None None None 20090522 Nonpathogen - hypothetical protein MA1669 13 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 20092297 Nonpathogen - mttA/Hcf106 family protein MA3486 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 20092939 Nonpathogen - hypothetical protein MA4146 1 None None None 20092348 Nonpathogen - hypothetical protein MA3541 2 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 20089764 Common - dipeptide ABC transporter, dipeptide-binding protein MA0880 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20093276 Nonpathogen - hypothetical protein MA4491 1 None None None 20089988 Common - transcriptional regulator, MarR family MA1122 85 COG1846 MarR, Transcriptional regulators Transcription 20090806 Common - acetolactate synthase MA1958 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 20091426 Nonpathogen - hypothetical protein MA2600 1 None None None 20091084 Common - coenzyme A ligase MA2244 130 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 20090885 Nonpathogen - hypothetical protein MA2038 1 None None None 20091666 Common moxR methanol dehydrogenase regulatory protein MA2842 177 COG0714 COG0714, MoxR-like ATPases General function prediction only 20090001 Nonpathogen - hypothetical protein MA1135 1 None None None 20091974 Nonpathogen - hypothetical protein MA3156 1 None None None 20088964 Common ssuA sulfonate ABC transporter, solute-binding protein MA0065 126 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 20091902 Nonpathogen - hypothetical protein MA3084 1 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 20090481 Common - hypothetical protein MA1626 2 None None None 20090248 Nonpathogen - hypothetical protein MA1387 1 None None None 20092915 Nonpathogen - hypothetical protein MA4122 1 None None None 20089493 Common idi isopentenyl pyrophosphate isomerase MA0604 81 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 20091820 Nonpathogen - hypothetical protein MA3002 2 None None None 20089347 Common mtaC1 methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 1 MA0456 164 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20092345 Nonpathogen - hypothetical protein MA3538 1 None None None 20092544 Common aldC acetolactate decarboxylase MA3746 39 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 20089162 Common - CDP-alcohol phosphatidyltransferase MA0264 84 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 20092270 Common nikC nickel ABC transporter, permease protein MA3458 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089541 Nonpathogen - hypothetical protein MA0654 25 COG4089 COG4089, Predicted membrane protein Function unknown 20091382 Common - sensory transduction histidine kinase MA2555 223 COG3322 COG3322, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 20089839 Common ubiA prenyltransferase MA0961 47 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 20091349 Nonpathogen - hypothetical protein MA2521 7 None None None 20092249 Common - branched chain amino acid transport protein AzlC MA3437 47 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 20092132 Nonpathogen - hypothetical protein MA3318 1 None None None 20090842 Common - hypothetical protein MA1994 6 None None None 20092231 Common - metallo-beta-lactamase MA3419 52 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 20088953 Nonpathogen - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MA0054 5 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 20091716 Common - hypothetical protein MA2895 93 COG0628 PerM, Predicted permease General function prediction only 20089372 Nonpathogen - hypothetical protein MA0483 1 None None None 20090284 Common - transcriptional regulator, Hth-3 family MA1424 113 COG1396 HipB, Predicted transcriptional regulators Transcription 20091038 Common nimD antibiotic resistance protein MA2197 39 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 20091153 Nonpathogen - hypothetical protein MA2315 1 None None None 20089169 Nonpathogen mtrF tetrahydromethanopterin S-methyltransferase subunit F MA0271 7 COG4218 MtrF, Tetrahydromethanopterin S-methyltransferase, subunit F Coenzyme metabolism 20092411 Common - lipolytic enzyme MA3611 175 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20091678 Nonpathogen - hypothetical protein MA2854 2 None None None 20092693 Common nifI2 P-II family nitrogen regulatory protein MA3897 180 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20088938 Nonpathogen - hypothetical protein MA0039 14 COG4022 COG4022, Uncharacterized protein conserved in archaea Function unknown 20089381 Nonpathogen - hypothetical protein MA0492 2 None None None 20089897 Common - indolepyruvate ferredoxin oxidoreductase, subunit alpha MA1022 115 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 20089030 Common - aspartate kinase MA0131 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 20092090 Common - hypothetical protein MA3275 59 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 20093145 Nonpathogen - hypothetical protein MA4358 1 None None None 20089892 Common - hypothetical protein MA1017 40 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 20092337 Common - transposase MA3529 41 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090488 Common nifH nitrogenase (iron protein) MA1633 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 20091616 Common - cell surface protein MA2793 70 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089896 Common - acetyl-CoA decarbonylase/synthase accessory protein MA1021 30 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 20091221 Nonpathogen - hypothetical protein MA2390 3 None None None 20088994 Nonpathogen - hypothetical protein MA0095 1 None None None 20089220 Common nadC nicotinate-nucleotide pyrophosphorylase (carboxylating) MA0322 198 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 20089196 Common - oligopeptide ABC transporter, ATP-binding protein MA0298 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20092281 Common - hypothetical protein MA3468 92 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 20089816 Common cobY nucleoside triphosphate (NTP):5-deoxyadenosylcobinamide phosphate nucleotidyltransferase MA0938 29 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 20091944 Common hdrB heterodisulfide reductase, subunit B MA3126 48 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 20093384 Common oppB oligopeptide ABC transporter, permease protein MA4600 216 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091089 Nonpathogen - hypothetical protein MA2250 2 None None None 20090382 Nonpathogen - 50S ribosomal protein L24e MA1523 30 COG2075 RPL24A, Ribosomal protein L24E Translation, ribosomal structure and biogenesis 20092946 Common atpI V-type ATP synthase subunit I MA4153 45 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 20093281 Nonpathogen - hypothetical protein MA4496 1 None None None 20090616 Nonpathogen - hypothetical protein MA1765 3 None None None 20089189 Nonpathogen - hypothetical protein MA0291 1 None None None 20092699 Common - sugar ABC transporter, ATP-binding protein MA3903 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 20093195 Nonpathogen - hypothetical protein MA4408 10 COG3355 COG3355, Predicted transcriptional regulator Transcription 20089212 Common - hypothetical protein MA0314 30 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 20092772 Common - acetyltransferase (GNAT) family protein MA3978 19 COG3393 COG3393, Predicted acetyltransferase General function prediction only 20093097 Nonpathogen - hypothetical protein MA4308 1 None None None 20091530 Common - cell surface protein MA2706 43 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089622 Nonpathogen - hypothetical protein MA0737 1 None None None 20092068 Common ocd alanine dehydrogenase MA3252 101 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 20091569 Common - hypothetical protein MA2746 112 COG1309 AcrR, Transcriptional regulator Transcription 20091217 Nonpathogen - hypothetical protein MA2386 1 None None None 20092587 Common ilvH acetolactate synthase 3 regulatory subunit MA3791 194 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 20089772 Common pstC phosphate ABC transporter, permease protein MA0888 227 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 20090017 Common - glutamine amidotransferase (class I) MA1151 180 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 20090924 Common - flavodoxin MA2078 23 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 20090115 Common - hypothetical protein MA1251 191 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20088982 Common ppx exopolyphosphatase MA0083 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 20093250 Common - dTDP-glucose 4,6-dehydratase MA4464 235 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 20092404 Nonpathogen - hypothetical protein MA3603 1 None None None 20089287 Nonpathogen - hypothetical protein MA0390 1 None None None 20092250 Common - branched chain amino acid transport protein AzlD MA3438 22 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 20089964 Common rpl15p 50S ribosomal protein L15P MA1094 34 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 20089182 Nonpathogen - hypothetical protein MA0284 15 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20090895 Nonpathogen - hypothetical protein MA2048 1 None None None 20089680 Nonpathogen - hypothetical protein MA0796 4 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20089983 Common czcD cation efflux system protein MA1117 210 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 20092657 Nonpathogen cdhB acetyl-CoA decarbonylase/synthase complex subunit epsilon MA3861 10 COG1880 CdhB, CO dehydrogenase/acetyl-CoA synthase epsilon subunit Energy production and conversion 20090903 Common - hypothetical protein MA2056 114 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 20089018 Common argD acetylornithine aminotransferase MA0119 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 20091888 Common cheW1 chemotaxis signal transduction coupling protein MA3070 137 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 20093175 Nonpathogen - hypothetical protein MA4388 1 None None None 20089468 Nonpathogen - transposase MA0579 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091644 Common - hypothetical protein MA2820 28 None None None 20091210 Nonpathogen - hypothetical protein MA2378 1 None None None 20091187 Common - hypothetical protein MA2353 22 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 20093047 Nonpathogen - hypothetical protein MA4257 2 None None None 20090576 Common - hypothetical protein MA1724 173 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20092290 Common - ferrous iron transport protein A MA3479 54 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 20090858 Nonpathogen - integral membrane protein MA2010 8 COG0170 SEC59, Dolichol kinase Lipid metabolism 20093057 Common pan proteasome-activating nucleotidase MA4268 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 20089037 Common - preprotein translocase subunit SecF MA0138 144 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 20091183 Common - sensory transduction histidine kinase MA2348 223 COG3322 COG3322, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 20090596 Common - hypothetical protein MA1744 171 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 161484941 Common cobN cobaltochelatase MA0385 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20093397 Common mttC membrane targeting/translocation system protein MA4616 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 20092154 Nonpathogen - hypothetical protein MA3340 1 None None None 20091652 Common - hypothetical protein MA2828 143 COG0327 COG0327, Uncharacterized conserved protein Function unknown 20089514 Common - hypothetical protein MA0626 35 None None None 20090338 Common hsp40 heat shock protein 40 MA1479 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 20092571 Nonpathogen - hypothetical protein MA3775 1 None None None 20092048 Nonpathogen - hypothetical protein MA3232 1 None None None 20089407 Nonpathogen - hypothetical protein MA0518 2 None None None 20092444 Nonpathogen - hypothetical protein MA3644 1 None None None 20091816 Nonpathogen - hypothetical protein MA2998 1 None None None 20092427 Common nifH nitrogenase (iron protein) MA3627 152 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 20092662 Nonpathogen - hypothetical protein MA3866 1 None None None 20091247 Common - hypothetical protein MA2416 4 None None None 20090715 Common - hypothetical protein MA1865 13 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 20092259 Nonpathogen - hypothetical protein MA3447 7 COG1504 COG1504, Uncharacterized conserved protein Function unknown 20092838 Common - hypothetical protein MA4045 7 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 20089377 Common - cell surface protein MA0488 21 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089780 Common - sodium/chloride-dependent transporter MA0901 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 20091053 Common - hypothetical protein MA2212 34 COG1378 COG1378, Predicted transcriptional regulators Transcription 20089769 Common - DNA-directed DNA polymerase MA0885 65 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 20093292 Common - DNA helicase RecQ MA4507 231 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 20089876 Common - hypothetical protein MA1000 43 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 20091449 Nonpathogen - hypothetical protein MA2626 4 None None None 20091470 Common atsB arylsulfatase regulator MA2647 120 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 20091828 Nonpathogen - hypothetical protein MA3010 2 None None None 20092180 Common - cation efflux system protein (cadmium/zinc/cobalt) MA3366 213 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 20093382 Common oppD oligopeptide ABC transporter, ATP-binding protein MA4598 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091307 Common - iron ABC transporter, solute-binding protein MA2476 202 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20090989 Common proW glycine betaine/L-proline ABC transporter, permease MA2146 194 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 20092747 Common - hypothetical protein MA3951 26 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 20090950 Common - hypothetical protein MA2106 107 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 20091288 Common slg cell surface glycoprotein (S-layer protein) MA2457 83 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20090304 Nonpathogen - hypothetical protein MA1445 1 None None None 20089828 Common - ferric enterobactin transport ATP-binding protein MA0950 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20091733 Common - AMP-binding protein MA2912 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 20089391 Nonpathogen - hypothetical protein MA0502 1 None None None 20091755 Common - hypothetical protein MA2936 37 COG1433 COG1433, Uncharacterized conserved protein Function unknown 20092041 Nonpathogen - hypothetical protein MA3225 1 None None None 20092024 Nonpathogen - hypothetical protein MA3208 3 COG0778 NfnB, Nitroreductase Energy production and conversion 20091492 Common pgk phosphoglycerate kinase MA2669 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 20089820 Common hisC histidinol-phosphate aminotransferase MA0942 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 20091766 Nonpathogen - hypothetical protein MA2947 3 None None None 20091919 Common - cell surface protein MA3101 45 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20092485 Nonpathogen - hypothetical protein MA3685 23 COG1860 COG1860, Uncharacterized protein conserved in archaea Function unknown 20092196 Common glnA glutamate-ammonia ligase MA3382 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 20091180 Common - LPS biosynthesis related protein MA2345 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20093376 Common - 3-dehydroquinate synthase MA4592 28 COG1465 COG1465, Predicted alternative 3-dehydroquinate synthase Amino acid transport and metabolism 20093149 Common - hypothetical protein MA4362 127 COG4048 COG4048, Uncharacterized protein conserved in archaea Function unknown 20091842 Common pmmB phosphomannomutase MA3024 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 20090214 Nonpathogen eif1A translation initiation factor IF-1A MA1353 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 20088917 Common - response regulator receiver MA0018 220 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 20092845 Common - alpha-amylase MA4052 25 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 20090144 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase MA1280 235 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 20089124 Nonpathogen - hypothetical protein MA0226 1 None None None 20090311 Nonpathogen - hypothetical protein MA1452 2 COG3794 PetE, Plastocyanin Energy production and conversion 20090377 Common net sodium/chloride-dependent noradrenaline transporter MA1518 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 20092497 Nonpathogen - hypothetical protein MA3697 1 None None None 20091332 Common - cation-transporting P-type ATPase MA2501 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 20093211 Common - hypothetical protein MA4425 14 COG4744 COG4744, Uncharacterized conserved protein Function unknown 20093089 Nonpathogen - hypothetical protein MA4300 1 None None None 20093218 Nonpathogen - hypothetical protein MA4432 10 COG1810 COG1810, Uncharacterized protein conserved in archaea Function unknown 20089690 Common - hypothetical protein MA0806 6 None None None 20092632 Nonpathogen - hypothetical protein MA3836 1 None None None 20090370 Nonpathogen - hypothetical protein MA1511 1 None None None 20091022 Common - polysaccharide biosynthesis protein MA2180 114 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 20093216 Nonpathogen mtd F420-dependent methylenetetrahydromethanopterin dehydrogenase MA4430 15 COG1927 Mtd, Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase Energy production and conversion 20089440 Common - sensory transduction histidine kinase MA0551 188 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089358 Nonpathogen - hypothetical protein MA0469 1 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 20090129 Common rpoB2 DNA-directed RNA polymerase subunit beta'' MA1265 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 20090325 Common thiI thiazole biosynthesis protein MA1466 96 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 20089269 Common pyrH uridylate kinase MA0372 238 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 20089912 Nonpathogen - hypothetical protein MA1040 4 None None None 20092531 Nonpathogen - hypothetical protein MA4664 1 None None None 20089758 Common - hypothetical protein MA0874 5 None None None 20090503 Common - hypothetical protein MA1650 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090131 Common - sensory transduction histidine kinase MA1267 221 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089247 Nonpathogen - hypothetical protein MA0349 1 None None None 20089324 Nonpathogen - hypothetical protein MA0432 3 None None None 20091867 Common oppB oligopeptide ABC transporter, permease protein MA3049 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091927 Nonpathogen - hypothetical protein MA3109 1 None None None 20090266 Nonpathogen - hypothetical protein MA1406 1 None None None 20092967 Common fmdF formylmethanofuran dehydrogenase, subunit F MA4174 173 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 20090040 Common gmd GDP-mannose 4,6-dehydratase MA1174 225 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 20090416 Nonpathogen - hypothetical protein MA1558 1 None None None 20091128 Common - hypothetical protein MA2290 23 COG5470 COG5470, Uncharacterized conserved protein Function unknown 20092995 Common - hypothetical protein MA4204 30 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090373 Nonpathogen - hypothetical protein MA1514 3 COG1753 COG1753, Uncharacterized conserved protein Function unknown 20090076 Common nifI1 P-II family nitrogen regulatory protein MA1212 186 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20092189 Common - hypothetical protein MA3375 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092953 Common atpD V-type ATP synthase subunit D MA4160 46 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 20090982 Common - hypothetical protein MA2139 56 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 20092959 Common - sugar transport family protein MA4166 150 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 20089020 Nonpathogen - hypothetical protein MA0121 33 COG1370 COG1370, Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit Posttranslational modification, protein turnover, chaperones 20092279 Common - SAM-dependent methyltransferase MA3466 25 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 20091141 Nonpathogen - hypothetical protein MA2303 1 None None None 20092288 Common feoB ferrous iron transport protein B MA3477 187 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 20090020 Nonpathogen - hypothetical protein MA1154 1 None None None 20093131 Common - cobalt transport family protein MA4343 56 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20090088 Nonpathogen - hypothetical protein MA1224 5 None None None 20092801 Common - hypothetical protein MA4006 37 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 20092364 Nonpathogen - hypothetical protein MA3558 1 None None None 20090097 Common - iron(III) ABC transporter, ATP-binding protein MA1233 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20090771 Common - hypothetical protein MA1922 48 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 20090445 Common - DNA topoisomerase VI subunit B MA1587 34 COG1389 COG1389, DNA topoisomerase VI, subunit B DNA replication, recombination, and repair 20092116 Nonpathogen - hypothetical protein MA3301 1 None None None 20090066 Common - iron ABC transporter, solute-binding protein MA1200 88 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20092972 Nonpathogen - hypothetical protein MA4179 1 None None None 20089553 Common - hypothetical protein MA0666 12 COG5423 COG5423, Predicted metal-binding protein Function unknown 20089319 Common - aldo/keto reductase MA0427 184 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20091300 Common - hypothetical protein MA2469 17 COG2128 COG2128, Uncharacterized conserved protein Function unknown 20089618 Common - hypothetical protein MA0733 10 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 20091464 Nonpathogen - hypothetical protein MA2641 1 None None None 20091479 Nonpathogen - hypothetical protein MA2656 2 None None None 20091063 Nonpathogen - hypothetical protein MA2223 2 None None None 20091726 Nonpathogen - hypothetical protein MA2905 3 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089285 Nonpathogen - hypothetical protein MA0388 4 None None None 20090748 Nonpathogen - hypothetical protein MA1898 1 None None None 20091359 Common pfpI intracellular protease I MA2531 166 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 20089611 Common lysA diaminopimelate decarboxylase MA0726 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 20092361 Common cbiM cobalt transport protein CbiM MA3554 88 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 20090766 Nonpathogen - hypothetical protein MA1917 1 None None None 20089251 Nonpathogen - hypothetical protein MA0353 4 None None None 20091534 Nonpathogen - hypothetical protein MA2710 1 None None None 20092035 Common - hypothetical protein MA3219 7 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 20089850 Nonpathogen - hypothetical protein MA0973 1 None None None 20093434 Nonpathogen - hypothetical protein MA4655 1 COG2105 COG2105, Uncharacterized conserved protein Function unknown 20090081 Nonpathogen vnfG nitrogenase, subunit delta MA1217 5 None None None 20089803 Common tyrB aromatic amino acid transferase MA0925 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 20092032 Common - bacterial leucyl aminopeptidase MA3216 74 COG2234 Iap, Predicted aminopeptidases General function prediction only 20089919 Common - transposase MA1047 39 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089847 Common - sensory transduction histidine kinase MA0970 161 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20091488 Common pmm phosphomannomutase MA2665 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 20092605 Nonpathogen - hypothetical protein MA3809 1 None None None 20091962 Nonpathogen - hypothetical protein MA3144 1 None None None 20089524 Nonpathogen slpM S-layer-like protein MA0637 12 None None None 20092660 Common cdhD acetyl-CoA decarbonylase/synthase complex subunit delta MA3864 20 COG2069 CdhD, CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) Energy production and conversion 20092471 Common - hypothetical protein MA3671 35 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 20090361 Nonpathogen fpoJ F(420)H(2) dehydrogenase, subunit FpoJ MA1502 5 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 20090690 Common - fructokinase MA1840 190 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 20089177 Common putP sodium:proline symporter (proline permease) MA0279 177 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 20092724 Nonpathogen - hypothetical protein MA3928 2 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 20092272 Common - hypothetical protein MA3459 198 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092893 Common proA gamma-glutamyl phosphate reductase MA4100 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 20089351 Nonpathogen - hypothetical protein MA0460 9 COG4742 COG4742, Predicted transcriptional regulator Transcription 20092932 Nonpathogen - hypothetical protein MA4139 1 None None None 20089842 Nonpathogen - hypothetical protein MA0964 1 None None None 20090669 Common ribH riboflavin synthase subunit beta MA1818 156 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 20093125 Common feoB ferrous iron transport protein B MA4337 174 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 20089005 Common cbiA1 cobyrinic acid a,c-diamide synthase MA0106 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 20089275 Common - acetyltransferase (GNAT) family protein MA0378 15 COG0456 RimI, Acetyltransferases General function prediction only 20093424 Nonpathogen - replication factor A MA4645 29 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 20089832 Common - hypothetical protein MA0954 10 None None None 20090788 Nonpathogen - hypothetical protein MA1939 1 None None None 20091280 Common - sterol-regulatory element-binding protein intramembrane protease MA2449 44 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 20093206 Common tgt archaeosine tRNA-ribosyltransferase MA4419 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 20091499 Common - hypothetical protein MA2678 9 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 20091294 Common - hypothetical protein MA2463 14 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 20089817 Common cobS cobalamin (5-phosphate) synthase MA0939 138 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 20093075 Nonpathogen - hypothetical protein MA4286 1 None None None 20089604 Common - hypothetical protein MA0719 115 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 20093007 Common - hypothetical protein MA4217 83 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 20091851 Common - uroporphyrin-III C-methyltransferase MA3033 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 20091276 Common - response regulator receiver MA2445 225 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 20092395 Nonpathogen - hypothetical protein MA3594 2 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 20089904 Common - hypothetical protein MA1029 27 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 20088910 Common cheD2 chemotaxis protein CheD MA0011 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 20093356 Common mrpA putative monovalent cation/H+ antiporter subunit A MA4572 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 20092325 Nonpathogen - hypothetical protein MA3517 1 None None None 20090679 Common - integrase MA1828 168 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20091215 Common - hypothetical protein MA2384 22 None None None 20091302 Common - hypothetical protein MA2471 20 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20091171 Nonpathogen - hypothetical protein MA2336 1 None None None 20091959 Nonpathogen - hypothetical protein MA3141 1 None None None 20093116 Nonpathogen - hypothetical protein MA4328 10 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 20092851 Nonpathogen - hypothetical protein MA4058 2 COG4742 COG4742, Predicted transcriptional regulator Transcription 20092812 Nonpathogen - hypothetical protein MA4018 3 None None None 20092314 Nonpathogen - hypothetical protein MA3504 7 None None None 20092637 Nonpathogen - transposase MA3841 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091408 Common - hypothetical protein MA2582 15 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20089812 Common mtbC dimethylamine corrinoid protein MA0934 168 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20089054 Nonpathogen - hypothetical protein MA0156 3 None None None 20089113 Nonpathogen - hypothetical protein MA0215 1 COG5513 COG5513, Predicted secreted protein Function unknown 20092769 Common - type IV secretion system protein MA3975 225 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 20089928 Common - transposase MA1057 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093263 Nonpathogen slg cell surface protein MA4478 18 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20091640 Common - GCN5-related N-acetyltransferase MA2816 25 COG0456 RimI, Acetyltransferases General function prediction only 20091997 Common kup potassium uptake protein Kup MA3179 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 20088947 Nonpathogen - hypothetical protein MA0048 1 None None None 20089767 Common - extracellular solute-binding protein, family 5 MA0883 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20092335 Common cdc48 cell division control protein 48 AAA family protein MA3527 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 20092356 Nonpathogen metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MA3549 4 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 20093052 Common cbiT precorrin-8W decarboxylase MA4263 96 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 20093236 Common - polysaccharide biosynthesis protein MA4450 73 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 20092564 Common neuA acylneuraminate cytidylyltransferase MA3766 132 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 20091803 Nonpathogen - hypothetical protein MA2985 1 None None None 20091269 Nonpathogen - hypothetical protein MA2438 10 None None None 20092323 Common - hypothetical protein MA3515 17 None None None 20089368 Common - cyclohexanol dehydrogenase MA0479 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 20090875 Common - transposase MA2027 88 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093321 Common - ABC transporter, solute-binding protein MA4536 95 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20089209 Common - outer membrane protein MA0311 88 COG2968 COG2968, Uncharacterized conserved protein Function unknown 20089628 Common - multiple antibiotic resistance protein (MarR family) MA0743 36 COG1846 MarR, Transcriptional regulators Transcription 20092054 Nonpathogen - hypothetical protein MA3238 2 None None None 20090201 Common cooC CODH nickel-insertion accessory protein MA1340 80 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 20090219 Common - copper binding protein, plastocyanin/azurin family MA1358 39 COG3794 PetE, Plastocyanin Energy production and conversion 20090944 Nonpathogen - hypothetical protein MA2100 1 None None None 20091440 Nonpathogen - hypothetical protein MA2614 1 None None None 20089880 Nonpathogen - hypothetical protein MA1004 1 None None None 20093304 Nonpathogen - hypothetical protein MA4519 14 COG4065 COG4065, Uncharacterized protein conserved in archaea Function unknown 20092147 Nonpathogen - hypothetical protein MA3333 1 None None None 20091002 Nonpathogen - hypothetical protein MA2160 3 None None None 20093187 Nonpathogen - hypothetical protein MA4400 2 None None None 20091160 Common - hypothetical protein MA2324 111 COG0432 COG0432, Uncharacterized conserved protein Function unknown 20091950 Nonpathogen - hypothetical protein MA3132 1 None None None 20091175 Nonpathogen - hypothetical protein MA2340 1 None None None 20090976 Common - hypothetical protein MA2133 95 COG3177 COG3177, Uncharacterized conserved protein Function unknown 20093367 Nonpathogen - hypothetical protein MA4583 1 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 20091605 Common - transcriptional regulator, TetR family MA2782 72 COG1309 AcrR, Transcriptional regulator Transcription 20089785 Common - microbial collagenase domain MA0906 30 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092219 Common - cytidine/deoxycytidylate deaminase family protein MA3407 212 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 20090694 Common - sensory transduction histidine kinase MA1844 180 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092880 Common - molybdenum cofactor biosynthesis protein MoeA2 MA4087 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 20090496 Nonpathogen - hypothetical protein MA1643 1 None None None 20089951 Common rps17p 30S ribosomal protein S17P MA1081 176 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 20091207 Common atsA arylsulfatase MA2375 143 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 20093229 Nonpathogen - hypothetical protein MA4443 1 None None None 20090197 Common - heavy-metal-associated protein MA1336 7 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 20090268 Nonpathogen - hypothetical protein MA1408 29 COG2237 COG2237, Predicted membrane protein Function unknown 20091139 Common - hypothetical protein MA2301 59 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 20089756 Common cobN cobaltochelatase MA0872 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20092247 Nonpathogen - hypothetical protein MA3435 1 None None None 20090458 Common - hypothetical protein MA1600 15 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20090581 Nonpathogen - hypothetical protein MA1729 4 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 20091683 Common argD acetylornithine aminotransferase MA2859 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 20092797 Nonpathogen - hypothetical protein MA4002 2 None None None 20091775 Nonpathogen - hypothetical protein MA2956 4 None None None 20091917 Nonpathogen - hypothetical protein MA3099 3 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 20090495 Common - alpha-amylase family protein MA1641 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 20092433 Nonpathogen - hypothetical protein MA3633 2 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 20090840 Nonpathogen - hypothetical protein MA1992 1 None None None 20089087 Common - helicase (SNF2 family) MA0189 136 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 20093222 Common - hypothetical protein MA4436 26 COG1891 COG1891, Uncharacterized protein conserved in archaea Function unknown 20092788 Nonpathogen - hypothetical protein MA3993 14 COG4051 COG4051, Uncharacterized protein conserved in archaea Function unknown 20091846 Nonpathogen - hypothetical protein MA3028 1 None None None 20088972 Nonpathogen - hypothetical protein MA0073 1 None None None 20090955 Common htpX heat shock protein HtpX MA2111 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 20091562 Common istB IstB helper protein MA2739 105 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20093028 Common - hypothetical protein MA4238 17 COG3543 COG3543, Uncharacterized conserved protein Function unknown 20089672 Common glnQ glutamine ABC transporter, ATP-binding protein MA0788 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 20092673 Common - hypothetical protein MA3877 32 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 20093290 Nonpathogen - hypothetical protein MA4505 13 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 20092527 Nonpathogen - hypothetical protein MA3730 31 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 20090760 Common dppD dipeptide ABC transporter, ATP-binding protein MA1911 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20092520 Common uppS di-trans-poly-cis-decaprenylcistransferase MA3723 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 20092641 Nonpathogen - hypothetical protein MA3845 2 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 20089217 Nonpathogen - hypothetical protein MA0319 1 None None None 20091119 Common modB molybdenum ABC transporter, permease protein MA2281 234 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 20092683 Common - hypothetical protein MA3887 40 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 20090014 Nonpathogen vhtC cytochrome b MA1148 2 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 20089458 Nonpathogen - hypothetical protein MA0569 2 None None None 20089043 Common mtmC1 monomethylamine corrinoid protein MA0145 164 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20090681 Nonpathogen - hypothetical protein MA1830 2 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 20093031 Common - hypothetical protein MA4241 34 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 20091196 Common - phosphoesterase MA2363 90 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 20089200 Common oppA oligopeptide ABC transporter, solute-binding protein MA0302 214 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20090271 Common - hypothetical protein MA1411 173 COG1202 COG1202, Superfamily II helicase, archaea-specific General function prediction only 20089310 Common fdh formaldehyde dehydrogenase MA0417 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 20091333 Common - hypothetical protein MA2502 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 20093403 Common - hypothetical protein MA4622 30 COG1378 COG1378, Predicted transcriptional regulators Transcription 20092461 Nonpathogen - hypothetical protein MA3661 3 None None None 20090626 Nonpathogen rpl37ae 50S ribosomal protein L37Ae MA1775 33 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 20089933 Common capK capsular polysaccharide biosynthesis protein MA1063 115 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 20092439 Nonpathogen - hypothetical protein MA3639 3 None None None 20091606 Nonpathogen - hypothetical protein MA2783 1 None None None 20092760 Common flr flavoredoxin MA3965 66 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 20091574 Common - hypothetical protein MA2751 79 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20091412 Nonpathogen - hypothetical protein MA2586 10 None None None 20092477 Nonpathogen - hypothetical protein MA3677 2 None None None 20092087 Common truD tRNA pseudouridine synthase D MA3271 91 COG0585 COG0585, Uncharacterized conserved protein Function unknown 20093334 Nonpathogen - methyl coenzyme M reductase, subunit beta MA4550 14 COG4054 McrB, Methyl coenzyme M reductase, beta subunit Coenzyme metabolism 20091321 Common - hypothetical protein MA2490 201 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 20091625 Nonpathogen - hypothetical protein MA2803 1 None None None 20091896 Nonpathogen - hypothetical protein MA3078 6 None None None 20090255 Nonpathogen - hypothetical protein MA1394 12 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 20091419 Nonpathogen - hypothetical protein MA2593 1 None None None 20091659 Common - transposase MA2835 76 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089665 Nonpathogen - hypothetical protein MA0781 4 COG4997 COG4997, Uncharacterized conserved protein Function unknown 20091590 Nonpathogen - hypothetical protein MA2767 1 None None None 20091176 Common - cytosine deaminase MA2341 166 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 20089133 Nonpathogen - hypothetical protein MA0235 4 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 20090390 Nonpathogen - hypothetical protein MA1531 12 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 20092277 Common - ABC transporter, ATP-binding protein MA3464 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20093317 Common - iron compounds ABC transporter, ATP-binding protein MA4532 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20092234 Common - hypothetical protein MA3422 25 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20089210 Nonpathogen - hypothetical protein MA0312 1 None None None 20090451 Common - hypothetical protein MA1593 16 COG5513 COG5513, Predicted secreted protein Function unknown 20092732 Common - hypothetical protein MA3936 59 COG1742 COG1742, Uncharacterized conserved protein Function unknown 20092944 Common - metallo cofactor biosynthesis protein MA4151 179 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20089999 Common - hypothetical protein MA1133 24 COG4832 COG4832, Uncharacterized conserved protein Function unknown 20091838 Common - hypothetical protein MA3020 187 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 20090776 Nonpathogen - hypothetical protein MA1927 1 None None None 20092208 Nonpathogen - hypothetical protein MA3396 2 None None None 20090149 Nonpathogen - hypothetical protein MA1285 2 None None None 20091560 Common - serine O-acetyltransferase MA2737 38 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 20090404 Common - hypothetical protein MA1546 59 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20092592 Nonpathogen - hypothetical protein MA3796 1 None None None 20088906 Common - hypothetical protein MA0007 171 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 20092305 Common - hypothetical protein MA3495 168 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20092556 Common - rhamnosyl transferase MA3758 119 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 20092887 Common - universal stress protein MA4094 118 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20089027 Nonpathogen - hypothetical protein MA0128 10 COG4081 COG4081, Uncharacterized protein conserved in archaea Function unknown 20092482 Common - hypothetical protein MA3682 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20090547 Nonpathogen - hypothetical protein MA1695 1 None None None 20089653 Nonpathogen - hypothetical protein MA0768 1 None None None 20091355 Nonpathogen - hypothetical protein MA2527 1 None None None 20090734 Nonpathogen - hypothetical protein MA1884 1 None None None 20092005 Nonpathogen - hypothetical protein MA3188 1 None None None 20090343 Common - geranylgeranyl reductase MA1484 126 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20090223 Common - O-linked GlcNAc transferase MA1362 207 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20090514 Common - peptidylprolyl isomerase MA1661 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 20090411 Nonpathogen - hypothetical protein MA1553 9 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 20093013 Nonpathogen - hypothetical protein MA4223 2 None None None 20090827 Common radC DNA repair protein RadC MA1979 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 20091619 Common - reverse transcriptase MA2797 92 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20091986 Common acdA acetate-CoA ligase (ADP-forming), subunit alpha MA3168 160 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 20092848 Common purL phosphoribosylformylglycinamidine synthase MA4055 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 20092504 Common - TPR-domain containing protein MA3704 164 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 20090621 Nonpathogen - hypothetical protein MA1770 2 None None None 20091762 Nonpathogen - hypothetical protein MA2943 1 None None None 20092161 Common - ribosomal RNA adenine dimethylase MA3347 38 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 20090254 Common - 3-isopropylmalate dehydratase MA1393 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 20090320 Common - hypothetical protein MA1461 10 None None None 20092190 Common - hypothetical protein MA3376 2 None None None 20093365 Common - phosphoribosyltransferase MA4581 57 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 20092372 Common argC N-acetyl-gamma-glutamyl-phosphate reductase MA3566 213 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 20092377 Nonpathogen - hypothetical protein MA3571 1 None None None 20088919 Common cheW2 chemotaxis signal transduction coupling protein MA0020 141 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 20089144 Common - 4-hydroxybenzoate decarboxylase MA0246 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 20089483 Common ipdC indolepyruvate decarboxylase MA0594 221 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 20089910 Nonpathogen - hypothetical protein MA1038 1 None None None 20093165 Common - sodium/potassium-transporting ATPase, alpha subunit MA4378 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 20091930 Nonpathogen - hypothetical protein MA3112 1 None None None 20089749 Nonpathogen - hypothetical protein MA0865 1 None None None 20092705 Common oppF oligopeptide ABC transporter, ATP-binding protein MA3909 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20090185 Nonpathogen - hypothetical protein MA1324 15 COG3366 COG3366, Uncharacterized protein conserved in archaea Function unknown 20091554 Common - hypothetical protein MA2730 140 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089723 Common - hypothetical protein MA0839 21 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 20090142 Nonpathogen - hypothetical protein MA1278 30 COG1701 COG1701, Uncharacterized protein conserved in archaea Function unknown 20091029 Common - transposase MA2188 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090033 Common prs ribose-phosphate pyrophosphokinase MA1167 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 20090432 Common sodB superoxide dismutase MA1574 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 20092856 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase MA4063 150 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 20093408 Nonpathogen - hypothetical protein MA4629 1 None None None 20090594 Nonpathogen - hypothetical protein MA1742 3 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090232 Nonpathogen - hypothetical protein MA1371 18 COG1849 COG1849, Uncharacterized protein conserved in archaea Function unknown 20092624 Nonpathogen - hypothetical protein MA3828 1 None None None 20093019 Nonpathogen - hypothetical protein MA4229 2 None None None 20090849 Common pepO endothelin converting enzyme homolog PepO MA2001 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 20090930 Common - cation efflux system protein MA2085 211 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 20091105 Nonpathogen - hypothetical protein MA2267 1 None None None 20089719 Nonpathogen fwuD formylmethanofuran dehydrogenase, subunit D MA0835 15 COG1153 FwdD, Formylmethanofuran dehydrogenase subunit D Energy production and conversion 20090173 Nonpathogen - hypothetical protein MA1310 1 None None None 20090937 Nonpathogen - hypothetical protein MA2092 1 None None None 20089238 Nonpathogen - Nop56-like protein MA0340 34 COG1498 SIK1, Protein implicated in ribosomal biogenesis, Nop56p homolog Translation, ribosomal structure and biogenesis 20091548 Common - hypothetical protein MA2724 28 COG3291 COG3291, FOG: PKD repeat General function prediction only 20093066 Nonpathogen rpl12p 50S ribosomal protein L12P MA4277 33 COG2058 RPP1A, Ribosomal protein L12E/L44/L45/RPP1/RPP2 Translation, ribosomal structure and biogenesis 20089580 Nonpathogen - hypothetical protein MA0695 15 COG2457 COG2457, Uncharacterized conserved protein Function unknown 20089561 Common bpl biotin operon repressor/biotin-pyruvate carboxylase ligase MA0676 231 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 20093189 Common - undecaprenyl diphosphate synthase MA4402 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 20089065 Common - hypothetical protein MA0167 6 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 20092895 Common proC pyrroline-5-carboxylate reductase MA4102 215 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 20089878 Common - malate dehydrogenase (oxaloacetate decarboxylating) (NADP+) MA1002 55 COG0281 SfcA, Malic enzyme Energy production and conversion 20089008 Nonpathogen - DNA primase large subunit MA0109 25 COG2219 PRI2, Eukaryotic-type DNA primase, large subunit DNA replication, recombination, and repair 20089129 Nonpathogen - hypothetical protein MA0231 1 None None None 20093310 Common - carbon-nitrogen hydrolase MA4525 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 20090003 Common hypB hydrogenase expression/formation protein MA1137 156 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 20089606 Nonpathogen rpoL DNA-directed RNA polymerase, subunit L MA0721 11 COG1761 RPB11, DNA-directed RNA polymerase, subunit L Transcription 20090993 Common fecE Fe(III) dicitrate ABC transporter, ATP-binding protein MA2150 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20089883 Common cydB cytochrome d ubiquinol oxidase, subunit II MA1007 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 20089430 Common hisF imidazole glycerol phosphate synthase subunit HisF MA0541 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 20089062 Common - hypothetical protein MA0164 25 COG3482 COG3482, Uncharacterized conserved protein Function unknown 20090510 Common - efflux pump antibiotic resistance protein MA1657 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20089531 Common eif2A translation initiation factor IF-2 subunit alpha MA0644 231 COG1093 SUI2, Translation initiation factor 2, alpha subunit (eIF-2alpha) Translation, ribosomal structure and biogenesis 20092937 Common draG ADP-ribosylglycohydrolase (dinitrogenase reductase activating glycohydrolase) MA4144 59 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 20091593 Common - transposase, mutator family domain MA4670 13 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092077 Common fxsA FxsA MA3261 71 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 20093425 Nonpathogen - hypothetical protein MA4646 1 None None None 20091036 Nonpathogen - hypothetical protein MA2195 1 None None None 20092906 Nonpathogen - 50S ribosomal protein L31e MA4113 30 COG2097 RPL31A, Ribosomal protein L31E Translation, ribosomal structure and biogenesis 20090561 Common - hypothetical protein MA1709 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 20090117 Nonpathogen - hypothetical protein MA1253 1 None None None 20090294 Nonpathogen - transposase MA1434 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091875 Common flaH flagellar accessory protein FlaH MA3057 40 COG2874 FlaH, Predicted ATPases involved in biogenesis of archaeal flagella Cell motility and secretion / Intracellular trafficking and secretion 20091522 Common - hypothetical protein MA2698 24 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 20092726 Nonpathogen - hypothetical protein MA3930 2 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091976 Nonpathogen - transposase MA3158 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092120 Nonpathogen - hypothetical protein MA3305 1 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 20091707 Common - cell surface protein MA2885 56 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20089410 Common cbiD cobalt-precorrin-6A synthase MA0521 85 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 20091786 Common - hypothetical protein MA2968 67 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 20093090 Common - cell surface protein MA4301 100 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20093101 Common - cell surface protein MA4312 101 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089070 Common trpS tryptophanyl-tRNA synthetase MA0172 52 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20092455 Common - ubiE/COQ5 methyltransferase MA3655 175 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089777 Nonpathogen - hypothetical protein MA0893 33 COG1094 COG1094, Predicted RNA-binding protein (contains KH domains) General function prediction only 20091125 Nonpathogen - hypothetical protein MA2287 3 None None None 20089059 Common - ferritin MA0161 76 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 20089958 Common rpl6p 50S ribosomal protein L6P MA1088 208 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 20091092 Common - hypothetical protein MA2253 59 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 20090658 Nonpathogen - hypothetical protein MA1807 1 None None None 20089593 Nonpathogen - hypothetical protein MA0708 6 None None None 20092867 Common - phenylacetyl-CoA ligase MA4074 115 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 20090334 Common - hypothetical protein MA1475 31 COG1821 COG1821, Predicted ATP-utilizing enzyme (ATP-grasp superfamily) General function prediction only 20090063 Common - iron ABC transporter, solute-binding protein MA1197 96 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091597 Common - iron ABC transporter, permease MA2774 92 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20092212 Common - hypothetical protein MA3400 12 COG4741 COG4741, Predicted secreted endonuclease distantly related to archaeal Holliday junction resolvase Nucleotide transport and metabolism 20090246 Common - aspartate aminotransferase MA1385 242 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 20090437 Common - transposase MA1579 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089796 Common - acetyltransferase (GNAT) family protein MA0918 41 COG0456 RimI, Acetyltransferases General function prediction only 20091870 Common valS valyl-tRNA synthetase MA3052 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20091042 Common istB IstB helper protein MA2201 105 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090237 Common - phosphoribosylaminoimidazole carboxylase MA1376 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 20091600 Common - iron(III) ABC transporter, solute-binding protein MA2777 67 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091937 Nonpathogen - hypothetical protein MA3119 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 20089944 Common rplW 50S ribosomal protein L23 MA1074 50 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 20092127 Common - hypothetical protein MA3312 13 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20092383 Nonpathogen - hypothetical protein MA3579 1 None None None 20089437 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase MA0548 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 20091363 Common - hypothetical protein MA2535 136 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20092743 Common - hypothetical protein MA3947 48 COG3439 COG3439, Uncharacterized conserved protein Function unknown 20091631 Nonpathogen - hypothetical protein MA4677 1 None None None 20089194 Nonpathogen - hypothetical protein MA0296 1 None None None 20089579 Common - CitG family protein MA0694 22 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 20090558 Nonpathogen - hypothetical protein MA1706 1 None None None 20090751 Common adh alcohol dehydrogenase (NADP+) MA1901 198 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 20089856 Common - hypothetical protein MA0979 16 None None None 20092516 Nonpathogen - hypothetical protein MA3718 9 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20092299 Common tatC translocase protein MA4667 196 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 20093041 Common oppC oligopeptide ABC transporter, permease protein MA4251 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20092513 Common nadE NAD synthetase MA3715 175 COG0171 NadE, NAD synthase Coenzyme metabolism 20089423 Common lysK lysyl-tRNA synthetase MA0534 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 20089026 Nonpathogen - hypothetical protein MA0127 3 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 20089710 Common hat histone acetyltransferase MA0826 92 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 20089041 Common mttP ethanolamine permease MA0143 153 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 20089374 Common - hypothetical protein MA0485 51 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 20089962 Common rps5p 30S ribosomal protein S5P MA1092 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 20090340 Common trkH sodium transport protein MA1481 144 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 20091527 Nonpathogen - hypothetical protein MA2703 5 None None None 20090811 Common - phosphoribosylformylglycinamidine synthase subunit I MA1963 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 20091614 Nonpathogen - hypothetical protein MA2791 1 None None None 20090631 Nonpathogen - hypothetical protein MA1780 1 None None None 20092659 Common cooC carbon-monoxide dehydrogenase accessory protein MA3863 30 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 20092862 Nonpathogen - hypothetical protein MA4069 5 None None None 20093099 Nonpathogen - hypothetical protein MA4310 6 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20090452 Nonpathogen - hypothetical protein MA1594 1 None None None 20091729 Common - cytochrome c peroxidase MA2908 95 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 20091719 Nonpathogen - hypothetical protein MA2898 1 None None None 20092114 Common - hypothetical protein MA3299 39 COG1900 COG1900, Uncharacterized conserved protein Function unknown 20089379 Common - sensory transduction histidine kinase MA0490 168 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092380 Nonpathogen - hypothetical protein MA3576 2 None None None 20089805 Nonpathogen - hypothetical protein MA0927 19 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 20092435 Common - hydrolase MA3635 163 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20090851 Common - sodium-dependent transporter MA2003 77 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 20092581 Nonpathogen - hypothetical protein MA3785 1 None None None 20091552 Common - ornithine decarboxylase MA2728 212 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 20089472 Common pyrD dihydroorotate dehydrogenase 1B MA0583 159 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 20089787 Common - hypothetical protein MA0909 43 COG1855 COG1855, ATPase (PilT family) General function prediction only 20091691 Common - polyferredoxin MA2867 98 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 20089706 Nonpathogen - hypothetical protein MA0822 16 COG1693 COG1693, Uncharacterized protein conserved in archaea Function unknown 20092580 Common - transcriptional regulator, ArsR family MA3784 115 COG0640 ArsR, Predicted transcriptional regulators Transcription 20090276 Nonpathogen - hypothetical protein MA1416 1 None None None 20090539 Common gptA xanthine-guanine phosphoribosyltransferase MA1687 81 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 20090897 Common dinF DNA damage-inducible protein MA2050 174 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 20092139 Common uvrA excinuclease ABC, subunit A MA3325 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 20092223 Common - multiple antibiotic resistance protein (MarC homolog) MA3411 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 20090318 Nonpathogen - hypothetical protein MA1459 2 None None None 20092108 Common - hypothetical protein MA3293 88 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 20092803 Common - Fun34 related protein MA4008 52 COG1584 COG1584, Predicted membrane protein Function unknown 20093156 Common - hydrogenase-3 subunit (EchB homolog) MA4369 64 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 20090301 Nonpathogen - hypothetical protein MA1442 33 COG1491 COG1491, Predicted RNA-binding protein Translation, ribosomal structure and biogenesis 20089035 Common - dCMP deaminase MA0136 115 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 20090133 Common - response regulator receiver MA1269 209 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 20091016 Common - galactoside O-acetyltransferase MA2174 202 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 20091051 Common trkA Trk potassium uptake system protein MA2210 155 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 20092007 Common - integral membrane protein MA3191 120 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 20092242 Common - cell surface protein MA3430 25 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 20091008 Common - hypothetical protein MA2166 8 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20091189 Nonpathogen - hypothetical protein MA2355 1 None None None 20092192 Nonpathogen - hypothetical protein MA3378 2 None None None 20092651 Nonpathogen - hypothetical protein MA3855 8 COG4031 COG4031, Predicted metal-binding protein General function prediction only 20089735 Common - cell surface protein MA0851 111 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089635 Nonpathogen - hypothetical protein MA0750 9 COG4742 COG4742, Predicted transcriptional regulator Transcription 20092614 Nonpathogen - hypothetical protein MA3818 1 None None None 20090389 Common - TolB protein homolog MA1530 75 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20091698 Nonpathogen - hypothetical protein MA2876 1 None None None 20092446 Common - transposase MA3646 108 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091995 Nonpathogen - hypothetical protein MA3177 1 None None None 20093252 Common - CAAX amino terminal protease family protein MA4466 30 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 20093283 Nonpathogen - hypothetical protein MA4498 1 None None None 20092573 Common rfbA glucose-1-phosphate thymidylyltransferase MA3777 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 20093313 Nonpathogen - hypothetical protein MA4528 1 None None None 20093138 Common moeA molybdenum cofactor biosynthesis protein MA4350 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 20089214 Common - phosphoribosylglycinamide formyltransferase MA0316 223 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 20092928 Nonpathogen - hypothetical protein MA4135 1 None None None 20091133 Common - flavoredoxin Flr MA2295 93 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 20092018 Nonpathogen - hypothetical protein MA3202 1 None None None 20092930 Common - hypothetical protein MA4137 25 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 20089016 Nonpathogen - hypothetical protein MA0117 21 COG2098 COG2098, Uncharacterized protein conserved in archaea Function unknown 20089273 Common - hypothetical protein MA0376 31 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 20091185 Common - hypothetical protein MA2350 60 COG5607 COG5607, Uncharacterized conserved protein Function unknown 20090926 Common - transposase MA2080 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092292 Common - hypothetical protein MA3481 147 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089782 Common - HesB family protein MA0903 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 20090713 Common - transcriptional regulator, MarR family MA1863 39 COG1846 MarR, Transcriptional regulators Transcription 20090094 Common - iron(III) ABC transporter, solute-binding protein MA1230 82 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20089022 Nonpathogen - hypothetical protein MA0123 1 None None None 20092775 Common kefC glutathione-regulated potassium-efflux system protein MA3981 214 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 20089491 Common mvk mevalonate kinase MA0602 72 COG1577 ERG12, Mevalonate kinase Lipid metabolism 20091428 Common - hypothetical protein MA2602 12 None None None 20092819 Nonpathogen - hypothetical protein MA4025 1 None None None 20090302 Nonpathogen - hypothetical protein MA1443 1 None None None 20090288 Common ccmC heme exporter protein C MA1428 178 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 20092691 Common nifH nitrogenase reductase MA3895 88 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 20092891 Nonpathogen - hypothetical protein MA4098 12 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 20091305 Common - iron ABC transporter, ATP-binding protein MA2474 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 20090413 Nonpathogen - hypothetical protein MA1555 2 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20091814 Nonpathogen - hypothetical protein MA2996 1 None None None 20090818 Common - hypothetical protein MA1970 158 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20091384 Nonpathogen - hypothetical protein MA2557 2 None None None 20090242 Common - GTP-binding protein MA1381 108 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 20093414 Nonpathogen - DNA primase MA4635 34 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 20090520 Common - integral membrane protein MA1667 52 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 20091388 Common - hypothetical protein MA2561 84 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 20090883 Common - hypothetical protein MA2035 4 None None None 20090363 Common fpoL F(420)H(2) dehydrogenase, subunit FpoL MA1504 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 20090477 Nonpathogen - hypothetical protein MA1621 1 None None None 20092913 Nonpathogen - hypothetical protein MA4120 7 COG2034 COG2034, Predicted membrane protein Function unknown 20093147 Common gldA gliding motility protein MA4360 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20091809 Common trpB tryptophan synthase subunit beta MA2991 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 20092174 Common - hypothetical protein MA3360 41 COG1578 COG1578, Uncharacterized conserved protein Function unknown 20093348 Common - 3,5-cyclic-nucleotide phosphodiesterase MA4564 85 COG1409 Icc, Predicted phosphohydrolases General function prediction only 20092629 Nonpathogen - hypothetical protein MA3833 1 None None None 20088904 Common - transposase MA0005 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090164 Nonpathogen - hypothetical protein MA1300 1 None None None 20092975 Common - reverse transcriptase MA4183 92 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20089167 Nonpathogen mtrH tetrahydromethanopterin S-methyltransferase subunit H MA0269 17 COG1962 MtrH, Tetrahydromethanopterin S-methyltransferase, subunit H Coenzyme metabolism 20089852 Common frhA coenzyme F420 hydrogenase, subunit alpha MA0975 105 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 20090282 Common - acyl-CoA synthetase MA1422 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20090368 Nonpathogen fpoO F(420)H(2) dehydrogenase, subunit FpoO MA1509 2 None None None 20091368 Common - hypothetical protein MA2541 11 None None None 20090122 Common - 30S ribosomal protein S7P MA1258 195 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 20089890 Nonpathogen cdhB acetyl-CoA decarbonylase/synthase complex subunit epsilon MA1015 10 COG1880 CdhB, CO dehydrogenase/acetyl-CoA synthase epsilon subunit Energy production and conversion 20090688 Common - cell surface protein MA1838 110 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20089249 Nonpathogen - integrase MA0351 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091024 Common - hypothetical protein MA2182 14 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 20092925 Common - transposase MA4132 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092703 Common oppC oligopeptide ABC transporter, permease protein MA3907 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091256 Nonpathogen mtbB dimethylamine methyltransferase MA2425 1 None None None 20088955 Common - hypothetical protein MA0056 32 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 20092130 Common - hypothetical protein MA3316 16 COG3422 COG3422, Uncharacterized conserved protein Function unknown 20088992 Nonpathogen - hypothetical protein MA0093 5 COG1645 COG1645, Uncharacterized Zn-finger containing protein General function prediction only 20092542 Common aldC acetolactate decarboxylase MA3744 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 20091942 Common - transposase MA3124 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091850 Common - alpha-amylase MA3032 169 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 20091949 Nonpathogen - hypothetical protein MA3131 1 None None None 20092011 Nonpathogen - small nuclear ribonucleoprotein MA3195 32 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 20090289 Common ccmB heme exporter protein B MA1429 44 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 20090007 Common vhtG F420-nonreducing hydrogenase MA1141 78 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 20089573 Common hdrD heterodisulfide reductase, subunit D MA0688 178 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 20093084 Common - hypothetical protein MA4295 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20090881 Common - nitrogenase-related protein MA2033 39 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20091664 Common - ABC transporter, ATP-binding protein MA2840 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20089998 Common - iron ABC transporter, ATP-binding protein MA1132 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20090702 Common - hypothetical protein MA1852 33 COG2445 COG2445, Uncharacterized conserved protein Function unknown 20093427 Common - hypothetical protein MA4648 121 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 20090474 Nonpathogen mtaB3 methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 3 MA1616 6 None None None 20090058 Common - carboxypeptidase MA1192 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 20092413 Common cmtM methylcobalamin:coenzyme M methyltransferase MA3613 69 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20091834 Common - phosphoesterase MA3016 68 COG0622 COG0622, Predicted phosphoesterase General function prediction only 20091458 Common - hypothetical protein MA2635 155 COG0628 PerM, Predicted permease General function prediction only 20091819 Common - hypothetical protein MA3001 25 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092983 Nonpathogen - hypothetical protein MA4192 1 None None None 20089612 Common - DNA-directed DNA polymerase, family X MA0727 81 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 20092671 Common - hydrolase family protein MA3875 164 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 20090408 Common - hypothetical protein MA1550 47 None None None 20089857 Nonpathogen - hypothetical protein MA0980 2 None None None 20092286 Nonpathogen - hypothetical protein MA3475 2 None None None 20089283 Common - protoporphyrin IX magnesium chelatase MA0386 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20090150 Common slg cell surface glycoprotein (S-layer protein) MA1286 24 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20091126 Nonpathogen - hypothetical protein MA2288 2 None None None 20091908 Nonpathogen - hypothetical protein MA3090 1 None None None 20091416 Nonpathogen - hypothetical protein MA2590 1 None None None 20090746 Nonpathogen - hypothetical protein MA1896 1 None None None 20091714 Common - hypothetical protein MA2893 86 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20089624 Common - hypothetical protein MA0739 69 COG5015 COG5015, Uncharacterized conserved protein Function unknown 20091747 Nonpathogen - hypothetical protein MA2928 1 None None None 20093390 Common - iron(III) ABC transporter, ATP-binding protein MA4606 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20089921 Common - transposase MA1050 83 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090786 Nonpathogen - carbon-nitrogen hydrolase MA1937 8 COG0388 COG0388, Predicted amidohydrolase General function prediction only 20092061 Nonpathogen - hypothetical protein MA3245 1 None None None 20090353 Nonpathogen - hypothetical protein MA1494 1 None None None 20090795 Common dhpS dihydropteroate synthase MA1946 55 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 20091444 Common - hypothetical protein MA2618 7 None None None 20089126 Nonpathogen - hypothetical protein MA0228 2 None None None 20089508 Common - sensory transduction histidine kinase MA0620 107 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089254 Nonpathogen - hypothetical protein MA0356 9 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089393 Nonpathogen - transcriptional regulator, ArsR family MA0504 14 COG4742 COG4742, Predicted transcriptional regulator Transcription 20092538 Common isf-17 iron-sulfur flavoprotein MA3740 41 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20093204 Common - hypothetical protein MA4417 24 COG2445 COG2445, Uncharacterized conserved protein Function unknown 20092669 Common psmB multicatalytic endopeptidase complex, subunit beta MA3873 48 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 20091784 Common - hypothetical protein MA2966 122 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 20091964 Nonpathogen - hypothetical protein MA3146 8 None None None 20092030 Common - hypothetical protein MA3214 10 None None None 20089353 Common - hypothetical protein MA0462 41 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 20089849 Common - catalase/peroxidase MA0972 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 20089917 Common - transposase MA1045 49 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092607 Nonpathogen - hypothetical protein MA3811 1 None None None 20089819 Common cobD cobalamin biosynthesis protein MA0941 147 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 20092125 Common argF ornithine carbamoyltransferase MA3310 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 20092056 Nonpathogen - hypothetical protein MA3240 1 None None None 20090673 Common - iron-sulfur cluster binding protein MA1822 81 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 20092941 Common - type 2 phosphatidic acid phosphatase Pap2 MA4148 85 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 20089548 Common nqr3 Na+-transporting NADH:ubiquinone oxidoreductase, subunit 3 MA0661 54 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 20090263 Nonpathogen - hypothetical protein MA1403 2 None None None 20092001 Nonpathogen - hypothetical protein MA3184 1 None None None 20091340 Common - hypothetical protein MA2509 33 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 20091061 Nonpathogen - hypothetical protein MA2221 9 COG4746 COG4746, Uncharacterized protein conserved in archaea Function unknown 20089894 Common - glutathione reductase (NADPH) MA1019 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 20089555 Common rfc replication factor C small subunit MA0669 248 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 20093278 Nonpathogen - hypothetical protein MA4493 2 None None None 20090912 Nonpathogen - hypothetical protein MA2065 1 None None None 20091198 Common - hypothetical protein MA2365 22 None None None 20091265 Common - F0F1 ATP synthase subunit alpha MA2434 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 20089175 Common - hypothetical protein MA0277 27 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 20092961 Nonpathogen - hypothetical protein MA4168 1 None None None 20090831 Nonpathogen - hypothetical protein MA1983 1 None None None 20092473 Common - hypothetical protein MA3673 28 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 20092418 Nonpathogen - hypothetical protein MA3618 1 None None None 20088988 Common - hypothetical protein MA0089 20 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 20089810 Nonpathogen mttB trimethylamine methyltransferase MA0932 12 COG5598 COG5598, Trimethylamine:corrinoid methyltransferase Coenzyme metabolism 20092749 Common - 4-carboxymuconolactone decarboxylase MA3953 17 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20092611 Nonpathogen - hypothetical protein MA3815 1 None None None 20091735 Common - transcriptional regulator, Hth-3 family MA2914 81 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 20092618 Nonpathogen - hypothetical protein MA3822 1 None None None 20092262 Nonpathogen - hypothetical protein MA3450 2 None None None 20089766 Common cobN cobaltochelatase MA0882 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20090039 Common gmd GDP-mannose 4,6-dehydratase MA1173 222 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 161484933 Nonpathogen - 30S ribosomal protein S3Ae MA3416 34 COG1890 RPS1A, Ribosomal protein S3AE Translation, ribosomal structure and biogenesis 20089822 Common - hypothetical protein MA0944 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090159 Common - nucleotidyltransferase MA1295 53 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20091330 Nonpathogen - hypothetical protein MA2499 8 COG4742 COG4742, Predicted transcriptional regulator Transcription 20093374 Common guaA GMP synthase subunit A MA4590 240 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 20093000 Nonpathogen - hypothetical protein MA4209 2 None None None 20090087 Common leuC 3-isopropylmalate dehydratase MA1223 207 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 20091474 Nonpathogen - hypothetical protein MA2651 4 COG2862 COG2862, Predicted membrane protein Function unknown 20089340 Common - methionine sulfoxide reductase B MA0449 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 20089663 Common cmtM methylcobalamin:coenzyme M methyltransferase MA0779 66 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20091472 Common - nonspecific acid phosphatase precursor MA2649 25 None None None 20092269 Common nikD nickel ABC transporter, ATP-binding protein MA3457 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20090636 Nonpathogen - hypothetical protein MA1785 1 None None None 20091826 Common - phosphoglycerate mutase family protein MA3008 72 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 20091106 Common - methylpurine DNA glycosylase MA2268 165 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 20091740 Nonpathogen - hypothetical protein MA2920 1 None None None 20090824 Common - hypothetical protein MA1976 14 COG5418 COG5418, Predicted secreted protein Function unknown 20092099 Common - universal stress protein MA3284 168 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20089334 Nonpathogen - hypothetical protein MA0443 1 None None None 20091286 Common - KlaA protein MA2455 35 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 20090379 Common - hypothetical protein MA1520 61 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20091511 Common - multidrug ABC transporter, permease protein MA4681 178 COG1511 COG1511, Predicted membrane protein Function unknown 20092847 Nonpathogen - hypothetical protein MA4054 1 None None None 20092487 Nonpathogen - hypothetical protein MA3687 18 COG1967 COG1967, Predicted membrane protein Function unknown 20092425 Nonpathogen - hypothetical protein MA3625 1 None None None 20093244 Nonpathogen - hypothetical protein MA4458 1 None None None 20089526 Common - rubrerythrin MA0639 82 COG1592 COG1592, Rubrerythrin Energy production and conversion 20089686 Nonpathogen - hypothetical protein MA0802 8 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089676 Common arcA arginine deiminase MA0792 24 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 20088915 Common cheY2 chemotaxis response regulator MA0016 202 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 20089864 Common - hypothetical protein MA0987 8 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 20092955 Nonpathogen - hypothetical protein MA4162 3 None None None 20089396 Common - antibiotic resistance protein McbG MA0507 48 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 20091656 Nonpathogen - hypothetical protein MA2832 1 None None None 20090447 Nonpathogen - hypothetical protein MA1589 2 None None None 20090323 Nonpathogen - hypothetical protein MA1464 2 None None None 20093389 Common - iron(III) ABC transporter, permease protein MA4605 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20090801 Nonpathogen - hypothetical protein MA1953 11 COG4742 COG4742, Predicted transcriptional regulator Transcription 20092080 Common - cysteine desulphurase MA3264 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 20090808 Nonpathogen - hypothetical protein MA1960 1 None None None 20091442 Nonpathogen - hypothetical protein MA2616 3 None None None 20089260 Common - flavodoxin MA0363 10 COG0716 FldA, Flavodoxins Energy production and conversion 20091431 Nonpathogen - hypothetical protein MA2605 1 None None None 20090069 Common nifH nitrogenase reductase MA1205 71 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 20090775 Common - hypothetical protein MA1926 17 COG2389 COG2389, Uncharacterized metal-binding protein General function prediction only 20088936 Nonpathogen - DNA polymerase II small subunit MA0037 24 COG1311 HYS2, Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B DNA replication, recombination, and repair 20089308 Common linC 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase MA0415 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 20089187 Common - hypothetical protein MA0289 102 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 20092026 Nonpathogen - hypothetical protein MA3210 1 None None None 20090029 Common - DNA repair exonuclease MA1163 35 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 20090127 Common rpoA1 DNA-directed RNA polymerase subunit alpha MA1263 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 20090498 Common - sensory transduction histidine kinase MA1645 191 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090375 Common - transport protein MA1516 139 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20092697 Common nifN nitrogenase associated protein N MA3901 59 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20092029 Nonpathogen - hypothetical protein MA3213 1 None None None 20090685 Common - hypothetical protein MA1835 30 COG1378 COG1378, Predicted transcriptional regulators Transcription 20093294 Nonpathogen - hypothetical protein MA4509 1 None None None 20090418 Nonpathogen - hypothetical protein MA1560 1 None None None 20092275 Common - ABC transporter, permease protein MA3462 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089180 Common - sulfate/molybdate ABC transporter, ATP-binding protein MA0282 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 20092991 Common - hypothetical protein MA4200 42 COG0622 COG0622, Predicted phosphoesterase General function prediction only 20091689 Nonpathogen - hypothetical protein MA2865 1 None None None 20090572 Nonpathogen - hypothetical protein MA1720 1 None None None 20089389 Nonpathogen - hypothetical protein MA0500 1 None None None 20092393 Common pgk phosphoglycerate kinase MA3592 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 20093227 Nonpathogen - hypothetical protein MA4441 1 None None None 20092667 Nonpathogen tfe archaeal transcription factor E MA3871 30 COG1675 TFA1, Transcription initiation factor IIE, alpha subunit Transcription 20090957 Nonpathogen - hypothetical protein MA2114 7 None None None 20090493 Common - hypothetical protein MA1638 15 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20092264 Common - iron ABC transporter, permease MA3452 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20089400 Nonpathogen - hypothetical protein MA0511 2 None None None 20090052 Common - hexosyltransferase MA1186 222 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20090490 Nonpathogen - hypothetical protein MA1635 3 None None None 20089517 Nonpathogen - hypothetical protein MA0629 4 None None None 20093023 Nonpathogen - hypothetical protein MA4233 14 COG5423 COG5423, Predicted metal-binding protein Function unknown 20092882 Common crcB CrcB family protein MA4089 153 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 20090424 Common pyrOB pyridoxine biosynthesis protein MA1566 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 20090741 Nonpathogen - hypothetical protein MA1891 1 None None None 20090428 Nonpathogen - hypothetical protein MA1570 1 None None None 20089072 Common - hypothetical protein MA0174 32 COG2445 COG2445, Uncharacterized conserved protein Function unknown 20092458 Common isf-16 iron-sulfur flavoprotein MA3658 36 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20091350 Nonpathogen - hypothetical protein MA2522 1 None None None 20090608 Common - hypothetical protein MA1757 8 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 20093026 Common hdrC heterodisulfide reductase, subunit C MA4236 58 COG1150 HdrC, Heterodisulfide reductase, subunit C Energy production and conversion 20092162 Nonpathogen - hypothetical protein MA3348 1 None None None 20089085 Common moaB molybdenum cofactor biosynthesis protein B MA0187 190 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 20092904 Nonpathogen rplX 50S ribosomal protein LX MA4111 11 COG2157 RPL20A, Ribosomal protein L20A (L18A) Translation, ribosomal structure and biogenesis 20090230 Nonpathogen - hypothetical protein MA4683 3 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 20092828 Nonpathogen - hypothetical protein MA4035 1 None None None 20093401 Common - hypothetical protein MA4620 108 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090315 Common - hypothetical protein MA1456 7 None None None 20092898 Common - hypothetical protein MA4105 12 COG3672 COG3672, Predicted periplasmic protein Function unknown 20091572 Nonpathogen - hypothetical protein MA2749 1 None None None 20093092 Nonpathogen - hypothetical protein MA4303 1 None None None 20092681 Nonpathogen - hypothetical protein MA3885 29 COG1779 COG1779, C4-type Zn-finger protein General function prediction only 20089794 Common - erythrocyte band 7 integral membrane protein MA0916 199 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 20091213 Common - hypothetical protein MA2382 37 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 20092502 Common - thioredoxin MA3702 168 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 20089219 Common - hypothetical protein MA0321 35 COG2014 COG2014, Uncharacterized conserved protein Function unknown 20089131 Nonpathogen - integral membrane protein MA0233 22 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 20090964 Common - hypothetical protein MA2121 75 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 20091414 Nonpathogen - hypothetical protein MA2588 1 None None None 20092600 Nonpathogen - hypothetical protein MA3804 1 None None None 20092714 Common amtB ammonium transporter MA3918 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 20090114 Common oppA oligopeptide ABC transporter, oligopeptide-binding protein MA1250 211 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20089674 Common ubiA prenyltransferase MA0790 70 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 20091361 Common pncB nicotinate phosphoribosyltransferase MA2533 71 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 20089138 Common - hypothetical protein MA0240 65 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 20090796 Nonpathogen - hypothetical protein MA1947 13 COG5423 COG5423, Predicted metal-binding protein Function unknown 20092865 Common - 4-carboxymuconolactone decarboxylase MA4072 75 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20092917 Common ssr site-specific recombinase MA4124 7 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20092808 Common gor glutathione reductase (NADPH) MA4013 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 20090273 Nonpathogen - Sm protein MA1413 22 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 20091339 Nonpathogen - hypothetical protein MA2508 25 COG2042 COG2042, Uncharacterized conserved protein Function unknown 20089003 Common surE stationary phase survival protein SurE MA0104 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 20090257 Nonpathogen - hypothetical protein MA1396 21 COG2150 COG2150, Predicted regulator of amino acid metabolism, contains ACT domain General function prediction only 20091323 Nonpathogen - hypothetical protein MA2492 1 None None None 20092385 Common - type I site-specific deoxyribonuclease MA3581 42 None None None 20091371 Nonpathogen - hypothetical protein MA2544 13 COG4189 COG4189, Predicted transcriptional regulator Transcription 20092745 Nonpathogen - hypothetical protein MA3949 2 None None None 20092210 Common - hypothetical protein MA3398 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20089152 Common - MoxR-related protein MA0254 158 COG0714 COG0714, MoxR-like ATPases General function prediction only 20091094 Common - response regulator receiver MA4671 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 20092969 Common fmdC formylmethanofuran dehydrogenase, subunit C MA4176 65 COG2218 FwdC, Formylmethanofuran dehydrogenase subunit C Energy production and conversion 20092240 Common - hypothetical protein MA3428 54 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 20092307 Common hyuA hydantoinase MA3497 118 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20092312 Common - transposase MA3502 22 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20092511 Nonpathogen - hypothetical protein MA3712 1 None None None 20089384 Nonpathogen - hypothetical protein MA0495 1 None None None 20091159 Nonpathogen - hypothetical protein MA2323 5 None None None 20091438 Nonpathogen - serine proteinase inhibitor MA2612 10 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 20091623 Nonpathogen - hypothetical protein MA2801 1 None None None 20091505 Common - phosphoribosyltransferase MA2685 74 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 20089222 Common modB molybdenum ABC transporter, permease protein MA0324 185 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 20093005 Nonpathogen - hypothetical protein MA4215 1 None None None 20090588 Nonpathogen - Mov34 family protein MA1736 21 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 20091753 Common - hypothetical protein MA2934 48 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 20089647 Common - ATP-dependent DNA helicase MA0762 238 COG1201 Lhr, Lhr-like helicases General function prediction only 20093073 Common - cell surface protein MA4284 122 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20093380 Common - hypothetical protein MA4596 58 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 20091296 Common dpm dolichyl-phosphate beta-D-mannosyltransferase related protein MA2465 177 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20092985 Common - ferredoxin MA4194 52 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 20089527 Nonpathogen - hypothetical protein MA0640 1 None None None 20089602 Common hpt adenine phosphoribosyltransferase MA0717 154 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 20090667 Common aspC aspartate aminotransferase MA1816 181 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 20092328 Common glyA glycine hydroxymethyltransferase MA3520 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 20091274 Common - hypothetical protein MA2443 68 COG2153 ElaA, Predicted acyltransferase General function prediction only 20090586 Nonpathogen - hypothetical protein MA1734 1 None None None 20091853 Common pqqE coenzyme PQQ synthesis protein E MA3035 164 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20093234 Common idh myo-inositol 2-dehydrogenase MA4448 192 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 20089935 Common - hypothetical protein MA1065 12 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 20091421 Nonpathogen - hypothetical protein MA2595 1 None None None 20092554 Common - N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein Spt14 MA3756 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20092767 Common - hypothetical protein MA3972 37 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 20091939 Nonpathogen - hypothetical protein MA3121 3 None None None 20092082 Common - hypothetical protein MA3266 17 COG4271 COG4271, Predicted nucleotide-binding protein containing TIR -like domain Transcription 20089595 Nonpathogen - hypothetical protein MA0710 2 None None None 20091966 Common moxR methanol dehydrogenase regulatory protein MA3148 181 COG0714 COG0714, MoxR-like ATPases General function prediction only 20090085 Common - hypothetical protein MA1221 34 COG1433 COG1433, Uncharacterized conserved protein Function unknown 20092358 Common cbiO cobalt ABC transporter, ATP-binding protein MA3551 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 20090486 Common vnfE nitrogenase associated protein E MA1631 62 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20092319 Common - hypothetical protein MA3511 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090946 Common - hypothetical protein MA2102 53 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20089915 Nonpathogen - hypothetical protein MA1043 2 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20090026 Nonpathogen - hypothetical protein MA1160 6 None None None 20091801 Nonpathogen - transposase MA2983 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093265 Nonpathogen - hypothetical protein MA4480 4 None None None 20092599 Nonpathogen - hypothetical protein MA3803 1 None None None 20090873 Nonpathogen - hypothetical protein MA2025 1 None None None 20091131 Nonpathogen - hypothetical protein MA2293 1 None None None 20092398 Nonpathogen - hypothetical protein MA3597 10 COG4189 COG4189, Predicted transcriptional regulator Transcription 20092457 Common - hypothetical protein MA3657 66 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 20092565 Common - N-acetylneuraminic acid phosphate synthase MA3767 76 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 20092547 Common - hypothetical protein MA3749 67 COG1971 COG1971, Predicted membrane protein Function unknown 20089889 Common cdhC acetyl-CoA decarbonylase/synthase complex subunit beta MA1014 19 COG1614 CdhC, CO dehydrogenase/acetyl-CoA synthase beta subunit Energy production and conversion 20089111 Common pepQ2 Xaa-Pro dipeptidase (cobalt-dependent) MA0213 239 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 20090435 Common - hypothetical protein MA1577 9 None None None 20089271 Common - hypothetical protein MA0374 201 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 20089207 Common fmdB formylmethanofuran dehydrogenase, subunit B MA0309 142 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 20093050 Common cbiF precorrin-4 C11-methyltransferase MA4261 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 20093369 Common - hypothetical protein MA4585 15 COG5513 COG5513, Predicted secreted protein Function unknown 20092187 Common ilvD dihydroxy-acid dehydratase MA3373 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 20088967 Nonpathogen - hypothetical protein MA0068 15 COG1470 COG1470, Predicted membrane protein Function unknown 20090601 Nonpathogen - cell surface glycoprotein MA1749 3 None None None 20091006 Nonpathogen - hypothetical protein MA2164 1 COG0500 SmtA, SAM-dependent methyltransferases Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 20091582 Nonpathogen - hypothetical protein MA2759 1 None None None 20093185 Nonpathogen - hypothetical protein MA4398 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089640 Common - choloylglycine hydrolase MA0755 50 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 20091311 Common - peptide ABC transporter, permease protein MA2480 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20092149 Nonpathogen - hypothetical protein MA3335 9 None None None 20092343 Nonpathogen - hypothetical protein MA3536 1 None None None 20090615 Common - cell surface protein MA1764 118 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092630 Nonpathogen - hypothetical protein MA3834 1 None None None 20090721 Nonpathogen - hypothetical protein MA1871 1 None None None 20092798 Common - clostripain MA4003 14 None None None 20091314 Nonpathogen - hypothetical protein MA2483 1 None None None 20089869 Nonpathogen - hypothetical protein MA0992 2 None None None 20089906 Common - hypothetical protein MA1031 42 COG2006 COG2006, Uncharacterized conserved protein Function unknown 20093306 Common - hypothetical protein MA4521 21 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 20090105 Common fmdB formylmethanofuran dehydrogenase, subunit B MA1241 110 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 20092643 Common - hypothetical protein MA3847 20 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20092728 Common - ribosomal RNA adenine dimethylase MA3932 52 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 20091178 Common - tropinesterase MA2343 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20089446 Common - hypothetical protein MA0557 8 None None None 20093103 Common - hypothetical protein MA4314 24 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20091877 Nonpathogen - hypothetical protein MA3059 7 None None None 20092468 Nonpathogen - hypothetical protein MA3668 8 None None None 20093198 Common - isochorismatase MA4411 80 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 20089106 Common truA tRNA pseudouridine synthase A MA0208 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 20089317 Common - hypothetical protein MA0425 37 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20092339 Common phzF phenazine biosynthesis protein MA3532 122 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 20089779 Nonpathogen eif1A translation initiation factor IF-1A MA0895 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 20092199 Nonpathogen - hypothetical protein MA3385 1 None None None 20092973 Common - hypothetical protein MA4180 93 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20089692 Common - homocysteine desulfhydrase MA0808 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 20089985 Nonpathogen - hypothetical protein MA1119 10 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20089583 Common oppD oligopeptide ABC transporter, ATP-binding protein MA0698 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091110 Common - ABC transporter, permease protein MA2272 183 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 20092142 Common - hypothetical protein MA3328 98 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 20089336 Common isf-6 iron-sulfur flavoprotein MA0445 56 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20091079 Common - hypothetical protein MA2239 101 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20089094 Nonpathogen - hypothetical protein MA0196 1 None None None 20091074 Nonpathogen - hypothetical protein MA2234 1 None None None 20092875 Common pacL cation-transporting ATPase MA4082 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 20089908 Nonpathogen - hypothetical protein MA1033 1 None None None 20093220 Nonpathogen - hypothetical protein MA4434 3 None None None 20093242 Nonpathogen - hypothetical protein MA4456 1 None None None 20089067 Common - class H tetracycline resistance efflux protein MA0169 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20091978 Common - ferredoxin MA3160 53 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 20091861 Common - haloacid dehalogenase-like hydrolase MA3043 35 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 20091971 Common - hypothetical protein MA3153 59 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 20092321 Nonpathogen - hypothetical protein MA3513 2 None None None 20091981 Nonpathogen - hypothetical protein MA3163 10 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 20089431 Common - hypothetical protein MA0542 76 COG1259 COG1259, Uncharacterized conserved protein Function unknown 20089833 Common nadC nicotinate-nucleotide pyrophosphorylase (carboxylating) MA0955 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 20092252 Common - hypothetical protein MA3440 14 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 20092375 Nonpathogen - hypothetical protein MA3569 1 None None None 20090216 Common - aldehyde dehydrogenase MA1355 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 20089608 Nonpathogen - transcriptional regulator MA0723 4 COG4742 COG4742, Predicted transcriptional regulator Transcription 20088974 Common - myo-inositol-1-phosphate synthase MA0075 57 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 20090970 Nonpathogen - hypothetical protein MA2127 1 None None None 20092351 Common - phosphoglycolate phosphatase MA3544 141 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 20089942 Common rpl3p 50S ribosomal protein L3P MA1072 155 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 20090166 Common - tungsten-containing aldehyde ferredoxin oxidoreductase cofactor modifying protein MA1302 172 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20091406 Common - WD-domain containing protein MA2580 96 COG2319 COG2319, FOG: WD40 repeat General function prediction only 20089725 Common - hypothetical protein MA0841 55 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090203 Common - P-type copper-transporting ATPase MA1342 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 20091082 Nonpathogen - hypothetical protein MA2242 1 None None None 20089727 Common dppC dipeptide ABC transporter, permease MA0843 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20090299 Common - HemK related protein MA1440 148 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 20092721 Nonpathogen - hypothetical protein MA3925 13 COG4871 COG4871, Uncharacterized protein conserved in archaea Function unknown 20093285 Nonpathogen - hypothetical protein MA4500 1 None None None 20089957 Common rps8p 30S ribosomal protein S8P MA1087 191 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 20090563 Nonpathogen - hypothetical protein MA1711 11 COG4090 COG4090, Uncharacterized protein conserved in archaea Function unknown 20091123 Common - large conductance mechanosensitive channel protein MA2285 23 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20090628 Nonpathogen rrp4 exosome complex RNA-binding protein Rrp4 MA1777 24 COG1097 RRP4, RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) Translation, ribosomal structure and biogenesis 20092815 Common - ABC transporter, ATP-binding protein MA4021 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 20093043 Common oppF oligopeptide ABC transporter, ATP-binding protein MA4253 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20090556 Common - sensory transduction histidine kinase MA1704 114 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089601 Nonpathogen - hypothetical protein MA0716 1 None None None 20090574 Nonpathogen - hypothetical protein MA1722 4 None None None 20088991 Nonpathogen - hypothetical protein MA0092 28 COG1698 COG1698, Uncharacterized protein conserved in archaea Function unknown 20089425 Nonpathogen - hypothetical protein MA0536 6 None None None 20091391 Common - transposase MA2565 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090822 Common - hypothetical protein MA1974 166 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 20093341 Nonpathogen - hypothetical protein MA4557 1 None None None 20090861 Common - sensory transduction histidine kinase MA2013 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20090644 Nonpathogen - hypothetical protein MA1793 4 None None None 20093069 Nonpathogen - hypothetical protein MA4280 4 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 20090983 Common uvrD DNA helicase MA2140 224 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 20092226 Nonpathogen - hypothetical protein MA3414 1 None None None 20089296 Nonpathogen - hypothetical protein MA0401 1 None None None 20090351 Nonpathogen - phytoene dehydrogenase family protein MA1492 9 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 20089774 Common pstB phosphate ABC transporter, ATP-binding protein MA0890 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 20092730 Common crcB CrcB family protein MA3934 171 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 20089056 Nonpathogen - hypothetical protein MA0158 8 None None None 20093254 Nonpathogen - hypothetical protein MA4468 1 None None None 20091517 Nonpathogen - hypothetical protein MA2693 1 None None None 20091657 Common - H(+)-transporting ATPase MA2833 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 20090357 Common fpoD F(420)H(2) dehydrogenase, subunit FpoD MA1498 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 20089231 Common - hypothetical protein MA0333 149 COG1733 COG1733, Predicted transcriptional regulators Transcription 20089516 Common - hypothetical protein MA0628 52 COG2006 COG2006, Uncharacterized conserved protein Function unknown 20091541 Common - NifU protein MA2717 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 20089349 Nonpathogen - hypothetical protein MA0458 1 None None None 20091245 Common hsdM site-specific DNA-methyltransferase (adenine-specific), subunit M MA2414 156 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 20089733 Common - hypothetical protein MA0849 38 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 20090931 Nonpathogen - hypothetical protein MA2086 1 None None None 20093015 Common - hypothetical protein MA4225 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092712 Common glnK nitrogen regulatory protein P-II MA3916 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20091836 Nonpathogen - hypothetical protein MA3018 16 COG3390 COG3390, Uncharacterized protein conserved in archaea Function unknown 20090221 Common - hypothetical protein MA1360 49 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20091620 Nonpathogen - hypothetical protein MA2798 1 None None None 20090292 Common - hypothetical protein MA1432 128 COG1881 COG1881, Phospholipid-binding protein General function prediction only 20091648 Nonpathogen - hypothetical protein MA2824 1 None None None 20091650 Common - hypothetical protein MA2826 168 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 20092635 Nonpathogen - hypothetical protein MA3839 1 None None None 161484938 Common nusA transcription elongation factor NusA-like protein MA1260 109 COG0195 NusA, Transcription elongation factor Transcription 20090465 Common - hypothetical protein MA1607 15 COG4828 COG4828, Predicted membrane protein Function unknown 20092594 Common - transposase MA3798 42 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 20091529 Nonpathogen - hypothetical protein MA2705 6 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20089474 Common hpcE 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase MA0585 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 20090501 Common - mutT/NUDIX family protein MA1648 17 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 20091957 Nonpathogen - tRNA synthetase domain MA3139 4 COG4085 COG4085, Predicted RNA-binding protein, contains TRAM domain General function prediction only 20089417 Nonpathogen mttB trimethylamine methyltransferase MA0528 12 COG5598 COG5598, Trimethylamine:corrinoid methyltransferase Coenzyme metabolism 20092370 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein MA3564 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 20090402 Common - hypothetical protein MA1544 28 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20093437 Common - hypothetical protein MA4658 55 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 20089082 Nonpathogen - hypothetical protein MA0184 12 COG4012 COG4012, Uncharacterized protein conserved in archaea Function unknown 20089747 Common - sensory transduction histidine kinase MA0863 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20092758 Common - sensory transduction histidine kinase MA3962 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20091231 Common gpmA phosphoglycerate mutase MA2400 151 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 20090187 Common merP mercury ion binding protein MA1326 87 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 20092525 Nonpathogen - hypothetical protein MA3728 6 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 20090512 Nonpathogen - rubredoxin MA1659 17 COG4802 FtrB, Ferredoxin-thioredoxin reductase, catalytic subunit Energy production and conversion 20089069 Common pheS phenylalanyl-tRNA synthetase subunit alpha MA0171 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 20090519 Common - integral membrane protein MA1666 115 COG2962 RarD, Predicted permeases General function prediction only 20093191 Nonpathogen - hypothetical protein MA4404 16 COG1693 COG1693, Uncharacterized protein conserved in archaea Function unknown 20090708 Common - membrane transport protein MA1858 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20088923 Common znuC zinc ABC transporter, ATP-binding protein MA0024 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 20090012 Common vhtG F420-nonreducing hydrogenase MA1146 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 20090140 Common - N-ethylammeline chlorohydrolase MA1276 189 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 20093123 Nonpathogen - hypothetical protein MA4335 1 None None None 20091261 Nonpathogen - hypothetical protein MA2430 29 COG1634 COG1634, Uncharacterized Rossmann fold enzyme General function prediction only 20092046 Nonpathogen - hypothetical protein MA3230 1 None None None 20092217 Common - sensory transduction histidine kinase MA3405 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20091087 Common - hypothetical protein MA2248 9 None None None 20092491 Nonpathogen - hypothetical protein MA3691 23 COG1412 COG1412, Uncharacterized proteins of PilT N-term./Vapc superfamily General function prediction only 20093411 Nonpathogen tgt archaeosine tRNA-ribosyltransferase MA4632 31 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 20091238 Common porB pyruvate synthase, beta subunit MA2407 123 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 20090008 Common vhtA F420-nonreducing hydrogenase MA1142 99 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 20091988 Common - hypothetical protein MA3170 24 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 20090545 Nonpathogen - hypothetical protein MA1693 1 None None None 20091920 Nonpathogen - hypothetical protein MA3102 19 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 20090046 Common - hexosyltransferase MA1180 47 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20092821 Common - DNA-damage-inducible protein P MA4027 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 20091764 Common - hypothetical protein MA2945 30 None None None 20090732 Common - transposase MA1882 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093193 Common - ABC transporter, ATP-binding protein MA4406 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 20089366 Common - hypothetical protein MA0477 28 COG1873 COG1873, Uncharacterized conserved protein Function unknown 20090701 Nonpathogen - hypothetical protein MA1851 2 None None None 20092622 Common - terminase MA3826 17 COG5362 COG5362, Phage-related terminase General function prediction only 20090235 Common - hypothetical protein MA1374 48 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 20091536 Nonpathogen - hypothetical protein MA2712 1 None None None 20092998 Common amt ammonium transporter MA4207 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 20089701 Nonpathogen - hypothetical protein MA0817 19 COG4021 COG4021, Uncharacterized conserved protein Function unknown 20090516 Nonpathogen - hypothetical protein MA1663 1 None None None 20090345 Common - moaA/nifB/pqqE family protein MA1486 170 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 20092498 Common - cell surface protein MA3698 113 COG3291 COG3291, FOG: PKD repeat General function prediction only 20093064 Common rpl1P 50S ribosomal protein L1P MA4275 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 20090847 Common - sulfate transporter MA1999 107 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 20089582 Common oppF oligopeptide ABC transporter, ATP-binding protein MA0697 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20093315 Common - transposase MA4530 88 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090147 Nonpathogen - hypothetical protein MA1283 1 None None None 20090978 Common - hypothetical protein MA2135 35 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 20091514 Common - lipolytic enzyme MA2691 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20091915 Nonpathogen - hypothetical protein MA3097 17 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 20092878 Common - hypothetical protein MA4085 16 COG4745 COG4745, Predicted membrane-bound mannosyltransferase Posttranslational modification, protein turnover, chaperones 20089732 Nonpathogen - hypothetical protein MA0848 2 None None None 20090177 Common - hypothetical protein MA1315 15 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092627 Nonpathogen - hypothetical protein MA3831 1 None None None 20090659 Nonpathogen - hypothetical protein MA1808 2 COG5323 COG5323, Uncharacterized conserved protein Function unknown 20092872 Common aldH6 aldehyde dehydrogenase (NAD(P)+) MA4079 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 20091543 Nonpathogen - hypothetical protein MA2719 19 COG2522 COG2522, Predicted transcriptional regulator General function prediction only 20091151 Common - polysaccharide biosynthesis protein MA2313 98 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 20089479 Nonpathogen - replication factor A MA0590 26 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 20090180 Common argH argininosuccinate lyase MA1318 220 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 20089332 Common dcd deoxyuridine 5'-triphosphate nucleotidohydrolase MA0440 29 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 20092620 Nonpathogen - hypothetical protein MA3824 1 None None None 20089414 Common - CDP-diacylglycerol-inositol 3-phosphatidyltransferase MA0525 65 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 20090189 Common - amino acid transporter MA1328 84 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 20091397 Common lig DNA ligase (ATP) MA2571 113 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 20091923 Common - hypothetical protein MA3105 5 None None None 20092911 Common purA adenylosuccinate synthase MA4118 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 20089120 Nonpathogen - hypothetical protein MA0222 3 None None None 20090198 Common merP mercury ion binding protein MA1337 130 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 20090225 Common - O-linked N-acetylglucosamine transferase MA1364 158 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 20092494 Nonpathogen - hypothetical protein MA3694 27 COG1909 COG1909, Uncharacterized protein conserved in archaea Function unknown 20089714 Nonpathogen - hypothetical protein MA0830 3 None None None 20090738 Nonpathogen - hypothetical protein MA1888 1 None None None 20092157 Common - hypothetical protein MA3343 241 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 20090346 Common tetR transcription regulation protein MA1487 9 COG1309 AcrR, Transcriptional regulator Transcription 20089741 Common hsp60-5 Hsp60 MA0857 243 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 20090322 Common - sensory transduction histidine kinase MA1463 114 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092215 Nonpathogen - hypothetical protein MA3403 1 None None None 20093246 Common - dTDP-glucose 4,6-dehydratase MA4460 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 20091551 Nonpathogen - hypothetical protein MA2727 8 None None None 20090236 Nonpathogen - hypothetical protein MA1375 1 None None None 20089502 Common trmM 1-methylguanosine tRNA methyltransferase MA0613 43 COG2520 COG2520, Predicted methyltransferase General function prediction only 20090220 Nonpathogen - hypothetical protein MA1359 1 None None None 20092144 Common - hypothetical protein MA3330 34 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 20091326 Common isf-14 iron-sulfur flavoprotein MA2495 35 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20092373 Nonpathogen - hypothetical protein MA3567 2 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 20090638 Nonpathogen - hypothetical protein MA1787 1 None None None 20089316 Nonpathogen - hypothetical protein MA0424 1 None None None 20092203 Nonpathogen - hypothetical protein MA3389 11 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089534 Nonpathogen - hypothetical protein MA0647 9 COG1711 COG1711, Uncharacterized protein conserved in archaea Function unknown 20090084 Common vnfN nitrogenase associated protein N MA1220 63 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20089090 Common - hypothetical protein MA0192 73 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 161484935 Common ppa inorganic pyrophosphatase MA2676 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 20091940 Common - surface antigen gene MA3122 92 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20088987 Common - DnaJ protein MA0088 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 20089232 Common - uncharacterized membrane protein MA0334 112 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 20091653 Nonpathogen - hypothetical protein MA2829 4 None None None 20090971 Nonpathogen - hypothetical protein MA2128 1 None None None 20090043 Common - polysaccharide ABC transporter, ATP-binding protein MA1177 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 20090865 Common - cell surface protein MA2017 59 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20093287 Common pyrB aspartate carbamoyltransferase catalytic subunit MA4502 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 20090867 Common pspA pneumococcal surface protein MA2019 14 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 20089489 Common rps2P 30S ribosomal protein S2 MA0600 126 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 20089198 Common oppC oligopeptide ABC transporter, permease protein MA0300 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089642 Nonpathogen - phosphoesterase MA0757 33 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 20090101 Common modA molybdate ABC transporter, solute-binding protein MA1237 166 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 20091539 Common metY O-acetylhomoserine (thiol)-lyase MA2715 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 20090072 Common anfK nitrogenase, subunit K MA1208 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20089419 Common - transmembrane protein MttP MA0530 6 None None None 20089511 Nonpathogen - hypothetical protein MA0623 1 None None None 20092459 Nonpathogen - hypothetical protein MA3659 1 None None None 20092884 Common - hypothetical protein MA4091 10 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 20089575 Common - hypothetical protein MA0690 31 COG1852 COG1852, Uncharacterized conserved protein Function unknown 20092008 Common - hypothetical protein MA3192 140 COG0432 COG0432, Uncharacterized conserved protein Function unknown 20090210 Nonpathogen - hypothetical protein MA1349 1 None None None 20093429 Common - hypothetical protein MA4650 172 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 20090193 Common - hypothetical protein MA1332 5 None None None 20091026 Nonpathogen - hypothetical protein MA2185 2 COG3503 COG3503, Predicted membrane protein Function unknown 20091101 Nonpathogen - hypothetical protein MA2262 4 COG4831 COG4831, Uncharacterized conserved protein Function unknown 20089793 Common nfeD nodulation protein NfeD MA0915 70 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 20091112 Nonpathogen - hypothetical protein MA2274 1 None None None 20089075 Nonpathogen - hypothetical protein MA0177 1 None None None 20092737 Common - hypothetical protein MA3941 88 COG0701 COG0701, Predicted permeases General function prediction only 20093093 Common - hypothetical protein MA4304 4 None None None 20089916 Common - transposase MA1044 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092636 Common - hypothetical protein MA3840 41 COG4748 COG4748, Uncharacterized conserved protein Function unknown 20091873 Nonpathogen flaJ flagellar assembly protein J MA3055 18 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 20092236 Common - hypothetical protein MA3424 34 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20090461 Common - hypothetical protein MA1603 150 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 20089130 Nonpathogen - hypothetical protein MA0232 2 None None None 20092420 Common - hypothetical protein MA3620 7 COG4891 COG4891, Uncharacterized conserved protein Function unknown 20089949 Nonpathogen rpmC 50S ribosomal protein L29 MA1079 12 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 20090530 Common - H(+)-transporting ATPase MA1678 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 20093340 Common - hypothetical protein MA4556 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 20092221 Nonpathogen - hypothetical protein MA3409 1 None None None 20090355 Common fpoB F(420)H(2) dehydrogenase, subunit FpoB MA1496 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 20091661 Common - sodium/alanine symporter MA2837 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 20089699 Common tyrS tyrosyl-tRNA synthetase MA0815 186 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20088998 Nonpathogen - hypothetical protein MA0099 8 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 20089011 Nonpathogen - archaeal transcription factor S MA0112 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 20090979 Common - hypothetical protein MA2136 35 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20092508 Common - hypothetical protein MA3709 80 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 20091880 Nonpathogen flaB flagellin MA3062 8 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 20089728 Common - ABC transporter, ATP-binding protein MA0844 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20092700 Common - ubiE/COQ5 methyltransferase MA3904 207 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20088951 Nonpathogen - hypothetical protein MA0052 1 None None None 20089088 Common - hypothetical protein MA0190 39 COG4279 COG4279, Uncharacterized conserved protein Function unknown 20089859 Common - Pin protein MA0982 7 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 20091745 Common - cell surface protein MA2926 10 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20090853 Nonpathogen - hypothetical protein MA2005 7 COG4073 COG4073, Uncharacterized protein conserved in archaea Function unknown 20092519 Nonpathogen - hypothetical protein MA3722 9 None None None 20092382 Common - type I restriction modification DNA protein MA3578 38 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 20092206 Nonpathogen - hypothetical protein MA3393 1 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 20091808 Common trpA tryptophan synthase subunit alpha MA2990 219 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 20090754 Common cstA carbon starvation protein A MA1905 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 20088920 Common - high-affinity gluconate transporter (gluconate permease) MA0021 62 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 20091120 Common modC molydbenum ABC transporter, ATP-binding protein MA2282 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 20091078 Nonpathogen - hypothetical protein MA2238 14 COG4022 COG4022, Uncharacterized protein conserved in archaea Function unknown 20089009 Nonpathogen pcnA DNA polymerase sliding clamp MA0110 34 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 20089745 Nonpathogen - hypothetical protein MA0861 2 None None None 20089146 Nonpathogen - hypothetical protein MA0248 1 None None None 20089240 Common - transcriptional regulator, ArsR family MA0342 19 COG4189 COG4189, Predicted transcriptional regulator Transcription 20092237 Common - hypothetical protein MA3425 15 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20091907 Nonpathogen - hypothetical protein MA3089 2 None None None 20093034 Common - hypothetical protein MA4244 32 COG1433 COG1433, Uncharacterized conserved protein Function unknown 20092253 Common - NADPH nitroreductase (oxygen-insensitive) MA3441 149 COG0778 NfnB, Nitroreductase Energy production and conversion 20092466 Nonpathogen - hypothetical protein MA3666 9 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 20091782 Nonpathogen - hypothetical protein MA2964 1 None None None 20091889 Common mcp-1 methyl-accepting chemotaxis protein MA3071 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 20092512 Common - acetyltransferase MA3713 166 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 20091993 Nonpathogen - hypothetical protein MA3175 1 COG3832 COG3832, Uncharacterized conserved protein Function unknown 20089428 Nonpathogen - hypothetical protein MA0539 1 None None None 20088927 Nonpathogen - hypothetical protein MA0028 1 None None None 20093226 Common - polysaccharide deacetylase MA4440 72 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20092301 Common - hypothetical protein MA3490 84 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 20089587 Nonpathogen - hypothetical protein MA0702 1 None None None 20091096 Nonpathogen - hypothetical protein MA2257 2 None None None 20091760 Common - hypothetical protein MA2941 9 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 20090430 Nonpathogen - hypothetical protein MA1572 1 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 20089452 Common - hypothetical protein MA0563 10 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 20090888 Common - hypothetical protein MA2041 7 COG5529 COG5529, Pyocin large subunit General function prediction only 20090565 Nonpathogen - hypothetical protein MA1713 17 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 20090401 Common - hypothetical protein MA1543 7 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20089598 Common - hypothetical protein MA0713 88 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 20089721 Nonpathogen - hypothetical protein MA0837 1 None None None 20093272 Nonpathogen - hypothetical protein MA4487 1 None None None 20090071 Nonpathogen - hypothetical protein MA1207 7 None None None 20089066 Nonpathogen - hypothetical protein MA0168 2 None None None 20092450 Nonpathogen - hypothetical protein MA3650 1 None None None 20089102 Nonpathogen - hypothetical protein MA0204 43 COG0433 COG0433, Predicted ATPase General function prediction only 20090662 Nonpathogen - hypothetical protein MA1811 6 COG3432 COG3432, Predicted transcriptional regulator Transcription 20091585 Common - transposase MA2762 108 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091239 Common menG 2-heptaprenyl-1,4-naphthoquinone methyltransferase MA2408 191 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20091405 Common - transposase MA2579 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20088963 Common ssuC sulfonate ABC transporter, permease protein MA0064 188 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 20091891 Common hmgA hydroxymethylglutaryl-CoA reductase (NADPH) MA3073 52 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 20089205 Common fmdC formylmethanofuran dehydrogenase, subunit C MA0307 64 COG2218 FwdC, Formylmethanofuran dehydrogenase subunit C Energy production and conversion 20092889 Nonpathogen - hypothetical protein MA4096 1 None None None 20092764 Common - geranylgeranylglyceryl phosphate synthase-like protein MA3969 32 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 20090528 Common - integral membrane protein MA1675 82 COG0730 COG0730, Predicted permeases General function prediction only 20091608 Common - hypothetical protein MA2785 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089206 Nonpathogen fmdD formylmethanofuran dehydrogenase, subunit D MA0308 15 COG1153 FwdD, Formylmethanofuran dehydrogenase subunit D Energy production and conversion 20092397 Common - ferredoxin MA3596 64 COG1146 COG1146, Ferredoxin Energy production and conversion 20089237 Common - hypothetical protein MA0339 37 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 20092218 Nonpathogen - hypothetical protein MA3406 8 None None None 20092095 Nonpathogen - hypothetical protein MA3280 2 None None None 20093003 Nonpathogen - hypothetical protein MA4213 1 COG5466 COG5466, Predicted small metal-binding protein Function unknown 20090394 Nonpathogen - hypothetical protein MA1535 1 None None None 20093326 Common - small heat shock protein MA4542 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 20090785 Common - hypothetical protein MA1936 28 COG0388 COG0388, Predicted amidohydrolase General function prediction only 20088976 Common - hypothetical protein MA0077 21 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 20090509 Common - hypothetical protein MA1656 21 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 20092353 Nonpathogen - phosphopantetheine adenylyltransferase MA3546 28 COG1019 COG1019, Predicted nucleotidyltransferase General function prediction only 20090056 Common - glucan 1,4-alpha-glucosidase MA1190 74 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 20090722 Nonpathogen - hypothetical protein MA1872 2 None None None 20089364 Nonpathogen - hypothetical protein MA0475 1 None None None 20091467 Common - hypothetical protein MA2644 24 COG4803 COG4803, Predicted membrane protein Function unknown 20091855 Nonpathogen - prion protein precursor MA3037 1 None None None 20090870 Nonpathogen - hypothetical protein MA2022 2 None None None 20089924 Common - polysaccharide biosynthesis protein MA1053 83 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 20092340 Nonpathogen - hypothetical protein MA3533 1 None None None 20092089 Nonpathogen - hypothetical protein MA3274 1 None None None 20088940 Nonpathogen - hypothetical protein MA0041 1 None None None 20091394 Nonpathogen - hypothetical protein MA2568 6 None None None 20089125 Nonpathogen - hypothetical protein MA0227 1 None None None 20088942 Common argS arginyl-tRNA synthetase MA0043 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20090877 Nonpathogen - hypothetical protein MA2029 1 None None None 20090482 Common - sensory transduction histidine kinase MA1627 178 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090846 Common - hypothetical protein MA1998 18 None None None 20092070 Common - O-GlcNAc transferase, p110 subunit MA3254 140 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20092387 Common - ABC transporter, permease protein MA3583 33 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 20089156 Common - transposase MA0258 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092786 Common cmd carboxymuconolactone decarboxylase MA3991 18 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20090005 Common hypD hydrogenase expression/formation protein MA1139 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 20089862 Nonpathogen - hypothetical protein MA0985 1 None None None 20090502 Common - hypothetical protein MA1649 10 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20089193 Nonpathogen - hypothetical protein MA0295 2 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 20091500 Common - transposase MA2679 25 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 20091259 Nonpathogen - hypothetical protein MA2428 1 COG3478 COG3478, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 20089773 Common pstA phosphate ABC transporter, permease protein MA0889 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 20093078 Common - cell surface protein MA4289 104 COG3291 COG3291, FOG: PKD repeat General function prediction only 20093118 Common - dolichyl-phosphate beta-D-mannosyltransferase MA4330 156 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20093172 Nonpathogen - hypothetical protein MA4385 1 None None None 20092329 Nonpathogen - hypothetical protein MA3521 1 None None None 20091156 Common - metallo-beta-lactamase MA2320 197 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 20090398 Common - hypothetical protein MA1539 18 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20090316 Nonpathogen - hypothetical protein MA1457 9 COG4044 COG4044, Uncharacterized protein conserved in archaea Function unknown 20093111 Common ogt methylated-DNA--protein-cysteine methyltransferase MA4322 222 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 20091279 Common - potassium channel protein MA2448 59 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 20093267 Nonpathogen - hypothetical protein MA4482 2 None None None 20093183 Common hyuA hydantoinase MA4396 115 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20089226 Common - flavoredoxin MA0328 71 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 20093104 Common - cell surface protein MA4315 79 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090011 Common - hypothetical protein MA1145 22 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 20091179 Nonpathogen - hypothetical protein MA2344 6 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 20092814 Common - ABC transporter, ATP-binding protein MA4020 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 20091367 Common - phycocyanin alpha phycocyanobilin lyase related protein MA2540 75 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 20092310 Nonpathogen - hypothetical protein MA3500 1 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 20092308 Common hyuA hydantoinase MA3498 119 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20091068 Nonpathogen - hypothetical protein MA2228 1 None None None 20091777 Nonpathogen - hypothetical protein MA2958 2 None None None 20088949 Common - hypothetical protein MA0050 34 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 20091164 Common - hypothetical protein MA2329 7 None None None 20093360 Nonpathogen - Hth5 family protein MA4576 18 COG1777 COG1777, Predicted transcriptional regulators Transcription 20089002 Common - GPR1/FUN34/yaaH family protein MA0103 46 COG1584 COG1584, Predicted membrane protein Function unknown 20092392 Common - hypothetical protein MA3591 78 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 20088934 Common - hypothetical protein MA0035 212 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 20090051 Common - UDP-glucose 4-epimerase MA1185 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 20093055 Nonpathogen - hypothetical protein MA4266 26 COG1831 COG1831, Predicted metal-dependent hydrolase (urease superfamily) General function prediction only 20092989 Common - hypothetical protein MA4198 16 COG2029 COG2029, Uncharacterized conserved protein Function unknown 20091780 Common - aldehyde ferredoxin oxidoreductase MA2962 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 20093300 Common argB acetylglutamate kinase MA4515 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 20089678 Common - tungsten-containing aldehyde ferredoxin oxidoreductase cofactor modifying protein MA0794 108 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20089650 Common - hypothetical protein MA0765 14 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 20089083 Common - multidrug efflux protein MA0185 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20092003 Nonpathogen - hypothetical protein MA3186 1 None None None 20089314 Common - aldo/keto reductase MA0422 187 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20092853 Nonpathogen - hypothetical protein MA4060 19 COG2522 COG2522, Predicted transcriptional regulator General function prediction only 20090018 Common glpX fructose 1,6-bisphosphatase II MA1152 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 20092645 Common - cellulase MA3849 91 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 20090940 Nonpathogen - hypothetical protein MA2095 1 None None None 20091932 Common - acetyltransferase (GNAT) family protein MA3114 16 COG0456 RimI, Acetyltransferases General function prediction only 20091709 Nonpathogen - hypothetical protein MA2887 1 None None None 20092524 Common - hypothetical protein MA3727 10 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 20091338 Common - cell surface protein MA2507 78 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 20088971 Common nrdD anaerobic ribonucleoside-triphosphate reductase MA0072 99 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 20089068 Common - hypothetical protein MA0170 32 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20090919 Common - hypothetical protein MA2073 10 None None None 20091200 Common - hypothetical protein MA2367 16 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20089952 Common rpl14p 50S ribosomal protein L14P MA1082 246 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 20091700 Common fwdB formylmethanofuran dehydrogenase, subunit B MA2878 19 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 20090951 Nonpathogen - hypothetical protein MA2107 1 None None None 20090120 Common ef1A elongation factor 1-alpha MA1256 249 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 20093406 Common - reverse transcriptase MA4626 92 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20092831 Nonpathogen - hypothetical protein MA4038 2 None None None 20092550 Nonpathogen - transmembrane oligosaccharyl transferase MA3752 20 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 20090215 Common - acetolactate synthase MA1354 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 20092785 Nonpathogen - metalloproteinase domain MA4674 6 COG5549 COG5549, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 20091629 Nonpathogen - hypothetical protein MA4678 1 None None None 20093307 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C MA4522 122 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 20091578 Common - hypothetical protein MA2755 3 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 20091688 Nonpathogen - hypothetical protein MA2864 1 None None None 20091108 Nonpathogen - hypothetical protein MA2270 7 COG3431 COG3431, Predicted membrane protein Function unknown 20092687 Nonpathogen - hypothetical protein MA3891 2 None None None 20093199 Nonpathogen - hypothetical protein MA4412 1 None None None 20091372 Nonpathogen - hypothetical protein MA2545 2 None None None 20090261 Nonpathogen - hypothetical protein MA1400 10 COG4883 COG4883, Uncharacterized protein conserved in archaea Function unknown 20092184 Common - sensory transduction histidine kinase MA3370 188 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20093258 Common dapA dihydrodipicolinate synthase MA4473 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 20089659 Common - phosphinothricin acetyltransferase MA0775 110 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 20091191 Common pcrA ATP-dependent DNA helicase MA2358 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 20091812 Common - hypothetical protein MA2994 51 COG4804 COG4804, Uncharacterized conserved protein Function unknown 20090798 Common - hypothetical protein MA1950 213 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 20089529 Nonpathogen - 3-isopropylmalate dehydratase MA0642 25 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 20093024 Common - hypothetical protein MA4234 22 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 20091018 Nonpathogen - hypothetical protein MA2176 4 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 20091509 Nonpathogen - hypothetical protein MA2688 1 None None None 20089563 Common - hypothetical protein MA0678 83 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 20091267 Common - H(+)-transporting ATP synthase, subunit C MA2436 93 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 20093136 Nonpathogen - hypothetical protein MA4348 1 None None None 20093358 Common - hsp20/alpha crystallin family protein MA4574 63 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 20090307 Common - hypothetical protein MA1448 25 COG1901 COG1901, Uncharacterized conserved protein Function unknown 20093071 Common - hypothetical protein MA4282 2 None None None 20089600 Nonpathogen - hypothetical protein MA0715 8 COG5643 COG5643, Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E General function prediction only 20089388 Common - hypothetical protein MA0499 26 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 20091991 Common - ABC transporter, permease protein MA3173 192 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 20093336 Nonpathogen - DNA polymerase II large subunit MA4552 25 COG1933 COG1933, Archaeal DNA polymerase II, large subunit DNA replication, recombination, and repair 20091143 Nonpathogen - hypothetical protein MA2305 1 None None None 20091979 Nonpathogen - hypothetical protein MA3161 1 None None None 20090640 Common topA DNA topoisomerase, type I MA1789 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 20090423 Nonpathogen - hypothetical protein MA1565 1 None None None 20090275 Nonpathogen - hypothetical protein MA1415 1 None None None 20091135 Nonpathogen - hypothetical protein MA2297 1 None None None 20091752 Common - hypothetical protein MA2933 57 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 20090426 Nonpathogen - hypothetical protein MA1568 1 None None None 20092824 Common - hypothetical protein MA4031 9 None None None 20091757 Common - hypothetical protein MA2938 16 None None None 20091218 Nonpathogen - hypothetical protein MA2387 3 None None None 20092079 Common - hypothetical protein MA3263 6 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 20092665 Nonpathogen - hypothetical protein MA3869 33 COG1499 NMD3, NMD protein affecting ribosome stability and mRNA decay Translation, ribosomal structure and biogenesis 20093029 Common - hypothetical protein MA4239 16 COG4887 COG4887, Uncharacterized metal-binding protein conserved in archaea General function prediction only 20091983 Common - hypothetical protein MA3165 172 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 20091433 Nonpathogen - hypothetical protein MA2607 1 None None None 20092164 Nonpathogen - hypothetical protein MA3350 1 None None None 20092020 Common - putative ATPase RIL MA3204 249 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 20089823 Nonpathogen - hypothetical protein MA0945 1 None None None 20091829 Nonpathogen - hypothetical protein MA3011 1 None None None 20091824 Common - formaldehyde-activating enzyme MA3006 27 COG1795 COG1795, Uncharacterized conserved protein Function unknown 20092940 Nonpathogen - metallo-beta-lactamase family protein MA4147 5 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 20092539 Common - flavoprotein MA3741 18 COG1036 COG1036, Archaeal flavoproteins Energy production and conversion 20089668 Common - hypothetical protein MA0784 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 20089867 Common - peptidoglycan GlcNAc deacetylase MA0990 102 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20090772 Nonpathogen - hypothetical protein MA1923 5 None None None 20091169 Nonpathogen - hypothetical protein MA2334 1 None None None 20091469 Common - transmembrane protein MA2646 105 COG0628 PerM, Predicted permease General function prediction only 20093214 Common - hypothetical protein MA4428 50 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 20093391 Common tpi triosephosphate isomerase MA4607 53 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 20090933 Common - TPR-domain containing protein MA2088 39 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20091193 Nonpathogen - hypothetical protein MA2360 2 None None None 20091968 Common pheA chorismate mutase/prephenate dehydratase MA3150 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 20090099 Common modC molybdate ABC transporter, ATP-binding protein MA1235 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 20089263 Common - hypothetical protein MA0366 86 COG0701 COG0701, Predicted permeases General function prediction only 20092958 Common cmtA methylcobalamin:CoM methyltransferase isozyme A MA4165 20 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20090036 Common - hypothetical protein MA1170 217 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 20089137 Common - acetyltransferase (GNAT) family protein MA0239 45 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 20092696 Common nifE nitrogenase associated protein E MA3900 66 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20090598 Nonpathogen - hypothetical protein MA1746 1 COG1470 COG1470, Predicted membrane protein Function unknown 20092964 Nonpathogen - hypothetical protein MA4171 3 None None None 20092739 Nonpathogen - hypothetical protein MA3943 2 None None None 20091724 Common - hypothetical protein MA2903 35 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20092449 Nonpathogen - hypothetical protein MA3649 1 None None None 20092841 Common serS seryl-tRNA synthetase MA4048 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 20090625 Nonpathogen rpoP DNA-directed RNA polymerase subunit P MA4672 14 COG1996 RPC10, DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) Transcription 20090839 Common - sensory transduction histidine kinase MA1991 176 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090440 Common - hypothetical protein MA1582 43 None None None 20090024 Common - acetyltransferase (GNAT) family protein MA1158 65 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 20092823 Nonpathogen - hypothetical protein MA4030 1 None None None 20089860 Nonpathogen - hypothetical protein MA0983 1 None None None 20091085 Nonpathogen - ferredoxin MA2245 1 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 20089234 Common - cell surface protein MA0336 73 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090044 Common - hypothetical protein MA1178 39 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20090603 Nonpathogen - cell surface glycoprotein MA1751 2 None None None 20090329 Common - sensory transduction histidine kinase MA1470 182 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089185 Common - hypothetical protein MA0287 40 COG1378 COG1378, Predicted transcriptional regulators Transcription 20090999 Common - periplasmic binding protein MA2156 52 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20089100 Common leuD 3-isopropylmalate dehydratase small subunit MA0202 205 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 20091494 Common yibO phosphoglyceromutase MA2671 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 20090803 Common - hypothetical protein MA1955 9 COG4127 COG4127, Uncharacterized conserved protein Function unknown 20090835 Nonpathogen - hypothetical protein MA1987 1 None None None 20088902 Common - sodium:proline symporter MA0003 179 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 20090125 Nonpathogen - 50S ribosomal protein L30e MA1261 28 COG1911 RPL30, Ribosomal protein L30E Translation, ribosomal structure and biogenesis 20089966 Common adk adenylate kinase MA1096 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 20089657 Common - NADPH:quinone reductase MA0773 184 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 20092535 Common - desulfoferrodoxin MA3737 31 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 20092619 Common - hypothetical protein MA3823 4 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 20092488 Common - integral membrane protein MA3688 45 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 20089939 Common - hypothetical protein MA1069 29 None None None 20091869 Common - haloacid dehalogenase-like hydrolase MA3051 29 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 20090170 Nonpathogen - hypothetical protein MA1307 9 COG4069 COG4069, Uncharacterized protein conserved in archaea Function unknown 20090632 Nonpathogen rnpB ribonuclease P, subunit p14 MA1781 20 COG1369 POP5, RNase P/RNase MRP subunit POP5 Translation, ribosomal structure and biogenesis 20088914 Common cheB2 chemotaxis protein-glutamate methylesterase MA0015 221 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 20089978 Common rps4p 30S ribosomal protein S4 MA1109 120 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 20092582 Common pyrK ferredoxin--NADP(+) reductase subunit alpha MA3786 93 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 20090249 Nonpathogen - hypothetical protein MA1388 1 None None None 20090909 Nonpathogen - hypothetical protein MA2062 1 None None None 20093314 Common istB IstB helper protein MA4529 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090683 Nonpathogen - hypothetical protein MA1832 1 None None None 20092268 Common nikE nickel ABC transporter, ATP-binding protein MA3456 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 20090666 Common - hypothetical protein MA1815 25 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 20091526 Common - hypothetical protein MA2702 10 None None None 20092816 Common - cobalt transport protein MA4022 71 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20089255 Nonpathogen - hypothetical protein MA0357 1 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089380 Common - bacterial extracellular solute-binding family 3 protein MA0491 157 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 20090570 Common - hypothetical protein MA1718 208 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20092415 Common - hypothetical protein MA3615 4 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 20091316 Common - hypothetical protein MA2485 17 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 20089558 Nonpathogen - hypothetical protein MA0673 7 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 20090959 Common - site-specific DNA-methyltransferase (adenine-specific), subunit M MA2116 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 20089736 Common bcrB bacitracin ABC transporter, permease protein MA0852 11 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20091681 Common - hypothetical protein MA2857 18 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 20092031 Nonpathogen - hypothetical protein MA3215 1 None None None 20093438 Nonpathogen - hypothetical protein MA4659 18 COG1931 COG1931, Uncharacterized protein conserved in archaea Function unknown 20090331 Nonpathogen - hypothetical protein MA1472 29 COG2888 COG2888, Predicted Zn-ribbon RNA-binding protein with a function in translation Translation, ribosomal structure and biogenesis 20091346 Common - hypothetical protein MA2518 41 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 20092368 Nonpathogen glkA ADP-specific phosphofructokinase MA3562 8 COG4809 COG4809, Archaeal ADP-dependent phosphofructokinase/glucokinase Carbohydrate transport and metabolism 20092559 Nonpathogen - hypothetical protein MA3761 1 None None None 20089844 Common - hypothetical protein MA0966 12 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 20092123 Nonpathogen - hypothetical protein MA3308 1 None None None 20089543 Common - 2'-5' RNA ligase MA0656 103 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 20093387 Nonpathogen - hypothetical protein MA4603 1 None None None 20091913 Common pstA phosphate ABC transporter, permease protein MA3095 224 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 20091615 Nonpathogen - hypothetical protein MA2792 1 None None None 20093109 Common - hypothetical protein MA4320 48 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 20090313 Common - cell surface lipoprotein MA1454 6 COG3794 PetE, Plastocyanin Energy production and conversion 20092097 Common cooS carbon-monoxide dehydrogenase, catalytic subunit MA3282 27 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 20089110 Common map methionine aminopeptidase MA0212 242 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 20092493 Nonpathogen rpoE2 DNA-directed RNA polymerase, subunit E2 MA3693 33 COG2093 COG2093, DNA-directed RNA polymerase, subunit E'' Transcription 20089405 Common - hypothetical protein MA0516 22 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 20089433 Common pcm-1 protein-L-isoaspartate (D-aspartate) O-methyltransferase MA0544 164 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 20092365 Nonpathogen cca tRNA CCA-pyrophosphorylase MA3559 34 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 20089118 Common fdhD formate dehydrogenase accessory protein MA0220 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 20093140 Common - hypothetical protein MA4352 193 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 20092729 Common fepC ferric transport protein MA3933 236 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20089279 Common - hypothetical protein MA0382 98 COG1720 COG1720, Uncharacterized conserved protein Function unknown 20089398 Common - surface antigen gene MA0509 89 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20091800 Nonpathogen - hypothetical protein MA2982 1 None None None 20090469 Common leuS leucyl-tRNA synthetase MA1611 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20093342 Common - hypothetical protein MA4558 170 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20089302 Common pcaC 4-carboxymuconolactone decarboxylase MA0409 74 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20092791 Nonpathogen - hypothetical protein MA3996 14 COG4029 COG4029, Uncharacterized protein conserved in archaea Function unknown 20092284 Common - hypothetical protein MA3472 35 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20091284 Nonpathogen - hypothetical protein MA2453 2 None None None 20091455 Common - transmembrane transport protein MA2632 8 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 20093134 Nonpathogen - hypothetical protein MA4346 1 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 20092403 Common acdB acetate-CoA ligase (ADP-forming), subunit beta MA3602 138 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 20089871 Nonpathogen - hypothetical protein MA0994 5 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20090154 Common - transposase MA1290 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090820 Common - hypothetical protein MA1972 30 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 20090917 Common - transposase MA2071 85 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 20088960 Nonpathogen - hypothetical protein MA0061 2 None None None 20090646 Nonpathogen - hypothetical protein MA1795 1 None None None 20093203 Common - hypothetical protein MA4416 20 COG1751 COG1751, Uncharacterized conserved protein Function unknown 20090448 Common - surface antigen gene MA1590 90 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20089298 Common - zinc-binding alcohol dehydrogenase MA0403 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 20091445 Nonpathogen - hypothetical protein MA2619 1 None None None 20089836 Common - L-aspartate dehydrogenase MA0958 49 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 20092552 Nonpathogen - transmembrane oligosaccharyl transferase MA3754 23 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 20089258 Common - flavodoxin MA0361 11 COG0716 FldA, Flavodoxins Energy production and conversion 20092136 Common - hypothetical protein MA3322 87 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 20089976 Common - hypothetical protein MA1107 3 None None None 20091423 Nonpathogen - hypothetical protein MA2597 1 None None None 20088956 Common - hypothetical protein MA0057 34 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 20090689 Common - hypothetical protein MA1839 74 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 20092530 Common mer methylenetetrahydromethanopterin reductase MA3733 37 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 20091039 Common - hypothetical protein MA2198 5 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 20093305 Common - coenzyme F420-dependent oxidoreductase MA4520 44 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 20089550 Common nqr5 Na+-transporting NADH:ubiquinone oxidoreductase, subunit 5 MA0663 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 20092548 Nonpathogen - hypothetical protein MA3750 10 None None None 20089013 Nonpathogen - hypothetical protein MA0114 13 COG4083 COG4083, Predicted membrane protein Function unknown 20090855 Common - hypothetical protein MA2007 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20089899 Common - hypothetical protein MA1024 13 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20092152 Common - hypothetical protein MA3338 19 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090467 Nonpathogen - hypothetical protein MA1609 1 None None None 20090068 Common - hypothetical protein MA1204 83 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 20089325 Common - CobW protein MA0433 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 20093256 Nonpathogen - hypothetical protein MA4470 2 None None None 20089160 Nonpathogen - hypothetical protein MA0262 1 None None None 20091228 Common - sensory transduction histidine kinase MA2397 113 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 20089980 Common - moaA/nifB/pqqE family protein MA1114 150 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 20091263 Nonpathogen - hypothetical protein MA2432 2 COG4485 COG4485, Predicted membrane protein Function unknown 20090745 Common - hypothetical protein MA1895 3 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 20089050 Nonpathogen - hypothetical protein MA0152 3 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 20089813 Nonpathogen - hypothetical protein MA0935 5 None None None 20090794 Common - hypothetical protein MA1945 72 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20093338 Common - SUA5/yciO/yrdC family protein MA4554 240 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 20091046 Common - hypothetical protein MA2205 17 COG5036 COG5036, SPX domain-containing protein involved in vacuolar polyphosphate accumulation Inorganic ion transport and metabolism 20089224 Common - quinone reductase MA0326 69 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 20090407 Nonpathogen - hypothetical protein MA1549 2 None None None 20091452 Common - triacylglycerol lipase MA2629 128 COG0657 Aes, Esterase/lipase Lipid metabolism 20089682 Common - N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein MA0798 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20090484 Common - transposase MA1629 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090672 Common - hypothetical protein MA1821 94 COG1900 COG1900, Uncharacterized conserved protein Function unknown 20091253 Common sodC superoxide dismutase MA2422 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 20090298 Common - NAD+ pyrophosphatase MA1439 124 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 20091670 Nonpathogen - hypothetical protein MA4676 1 None None None 20090244 Nonpathogen - hypothetical protein MA1383 4 None None None 20090359 Common fpoI F(420)H(2) dehydrogenase, subunit FpoI MA1500 199 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 20091044 Common - cellulosomal protein MA2203 14 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 20092330 Common purN phosphoribosylglycinamide formyltransferase MA3522 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 20090473 Common cmtM methylcobalamin:coenzyme M methyltransferase MA1615 97 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20089165 Nonpathogen - hypothetical protein MA0267 1 None None None 20091955 Common - peptidylprolyl isomerase MA3137 162 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 20092173 Common - iron(III) ABC transporter, permease protein MA3359 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20092014 Common trpB tryptophan synthase subunit beta MA3198 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 20089807 Common - transmembrane protein MttP MA0929 9 None None None 20092261 Common - hypothetical protein MA3449 85 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 20091234 Common rad25 DNA repair protein MA2403 107 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 20088925 Nonpathogen - hypothetical protein MA0026 1 None None None 20091909 Nonpathogen - hypothetical protein MA3091 2 None None None 20091342 Common - universal stress protein MA2512 123 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20092776 Nonpathogen - hypothetical protein MA3982 1 None None None 20092577 Common rfbM mannose-1-phosphate guanylyltransferase (GDP) MA3781 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 20089937 Common - polysaccharide deacetylase MA1067 71 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20089955 Common rpl5p 50S ribosomal protein L5P MA1085 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 20093416 Common rtcA RNA 3'-terminal-phosphate cyclase MA4637 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 20092570 Nonpathogen - hypothetical protein MA3774 1 None None None 20088980 Common ppk polyphosphate kinase MA0081 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 20090815 Common cooC CODH nickel-insertion accessory protein MA1967 114 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 20091242 Nonpathogen - hypothetical protein MA2411 1 None None None 20089702 Nonpathogen - hypothetical protein MA0818 16 COG1873 COG1873, Uncharacterized conserved protein Function unknown 20088969 Nonpathogen - hypothetical protein MA0070 1 None None None 20090455 Common - hypothetical protein MA1597 88 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 20090726 Nonpathogen - hypothetical protein MA1876 1 None None None 20089505 Common - 2-cys peroxiredoxin, subunit A MA0616 183 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 20092860 Common - hypothetical protein MA4067 23 COG2155 COG2155, Uncharacterized conserved protein Function unknown 20092615 Nonpathogen - hypothetical protein MA3819 1 None None None 20091947 Nonpathogen - hypothetical protein MA3129 10 COG4738 COG4738, Predicted transcriptional regulator Transcription 20092038 Common - hypothetical protein MA3222 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089520 Nonpathogen - hypothetical protein MA0633 2 None None None 20089708 Nonpathogen - hypothetical protein MA0824 5 None None None 20091925 Common - hypothetical protein MA3107 3 None None None 20089571 Nonpathogen - hypothetical protein MA0686 1 None None None 20091057 Nonpathogen - hypothetical protein MA2216 1 None None None 20089354 Common - ferredoxin MA0463 165 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 20089034 Common - F420-0--gamma-glutamyl ligase MA0135 44 COG1478 COG1478, Uncharacterized conserved protein Function unknown 20090613 Common - cell surface protein MA1762 127 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092595 Common - hypothetical protein MA3799 25 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091612 Nonpathogen - hypothetical protein MA2789 1 None None None 20091486 Common - hypothetical protein MA2663 19 COG4907 COG4907, Predicted membrane protein Function unknown 20089498 Nonpathogen - H/ACA RNA-protein complex component Gar1 MA0609 8 COG3277 GAR1, RNA-binding protein involved in rRNA processing Translation, ribosomal structure and biogenesis 20089454 Nonpathogen - hypothetical protein MA0565 3 None None None 20091375 Common - ABC transporter, ATP-binding protein MA2548 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20091961 Common - integral membrane protein MA3143 12 COG0170 SEC59, Dolichol kinase Lipid metabolism 20089712 Nonpathogen - hypothetical protein MA0828 1 None None None 20091730 Common vorA 2-oxoisovalerate ferredoxin oxidoreductase, alpha subunit MA2909 111 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 20089172 Nonpathogen mtrC tetrahydromethanopterin S-methyltransferase subunit C MA0274 14 COG4061 MtrC, Tetrahydromethanopterin S-methyltransferase, subunit C Coenzyme metabolism 20090470 Nonpathogen - hypothetical protein MA1612 1 None None None 20092159 Common gap glyceraldehyde-3-phosphate dehydrogenase MA3345 58 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 20092109 Nonpathogen - hypothetical protein MA3294 2 COG0388 COG0388, Predicted amidohydrolase General function prediction only 20091415 Nonpathogen - hypothetical protein MA2589 1 None None None 20091674 Common - hypothetical protein MA2850 29 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 20089632 Common - hypothetical protein MA0747 5 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20089463 Common nirD heme d1 biosynthesis protein precursor NirD MA0574 53 COG1522 Lrp, Transcriptional regulators Transcription 20092936 Nonpathogen - hypothetical protein MA4143 1 None None None 20091565 Common - nitroreductase MA2742 65 COG0778 NfnB, Nitroreductase Energy production and conversion 20091034 Common - hypothetical protein MA2193 129 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 20089461 Nonpathogen - hypothetical protein MA0572 2 None None None 20091713 Nonpathogen - hypothetical protein MA2891 1 None None None 20089291 Common cbiO cobalt ABC transporter, ATP-binding protein MA0394 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 20090758 Common - hypothetical protein MA1909 44 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 20091559 Nonpathogen - hypothetical protein MA2735 1 None None None 20092708 Common - hypothetical protein MA3912 3 None None None 20093163 Common - response regulator receiver MA4376 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 20091318 Nonpathogen - hypothetical protein MA2487 1 None None None 20091694 Common - hypothetical protein MA2870 28 COG4802 FtrB, Ferredoxin-thioredoxin reductase, catalytic subunit Energy production and conversion 20092929 Nonpathogen - hypothetical protein MA4136 1 None None None 20089613 Common lig DNA ligase (ATP) MA0728 102 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 20090891 Common - hypothetical protein MA2044 2 None None None 20089638 Nonpathogen - hypothetical protein MA0753 2 None None None 20089342 Common - beta-phosphoglucomutase MA0451 179 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 20090711 Common - hypothetical protein MA1861 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 20093371 Common srp54 signal recognition particle protein Srp54 MA4587 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 20089591 Nonpathogen - hypothetical protein MA0706 3 None None None 20091114 Common - transcriptional regulator, Hth-3 family MA4668 66 COG1476 COG1476, Predicted transcriptional regulators Transcription 20090112 Common - ubiE/COQ5 methyltransferase MA1248 180 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090074 Common anfD nitrogenase, subunit D MA1210 59 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20089376 Common - hypothetical protein MA0487 23 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20090285 Common - transposase MA1425 46 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092804 Common - hypothetical protein MA4009 15 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 20089961 Nonpathogen rpl18p 50S ribosomal protein L18P MA1091 34 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 20090706 Nonpathogen - hypothetical protein MA1856 7 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 20093295 Nonpathogen - hypothetical protein MA4510 1 None None None 20092293 Common - moaA/nifB/pqqE family protein MA3482 91 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 20092244 Common - hypothetical protein MA3432 32 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 20090927 Common - sensory transduction histidine kinase MA2082 164 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20091727 Common - hypothetical protein MA2906 15 None None None 20091900 Common flaI flagella accessory protein I MA3082 225 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 20090718 Common - hypothetical protein MA1868 100 COG3177 COG3177, Uncharacterized conserved protein Function unknown 20092113 Common comDE sulfopyruvate decarboxylase MA3298 35 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 20091080 Nonpathogen - hypothetical protein MA2240 1 None None None 20093393 Common - DNA-(apurinic or apyrimidinic site) lyase MA4609 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 20093179 Nonpathogen mtaB2 methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 2 MA4392 6 None None None 20088989 Common pheRS O-phosphoseryl-tRNA synthetase MA0090 45 COG2024 COG2024, Phenylalanyl-tRNA synthetase alpha subunit (archaeal type) Translation, ribosomal structure and biogenesis 20091146 Nonpathogen - hypothetical protein MA2308 1 None None None 20089660 Nonpathogen - hypothetical protein MA0776 1 None None None 20092273 Nonpathogen - hypothetical protein MA3460 1 None None None 20093159 Common - hydrogenase-3, subunit E (HycE homolog) MA4372 192 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 20091299 Common - hypothetical protein MA2468 35 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20089730 Common - ABC-2 type transporter MA0846 207 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 20090526 Nonpathogen - hypothetical protein MA1673 1 None None None 20088909 Common ftr tetrahydromethanopterin formyltransferase MA0010 24 COG2037 Ftr, Formylmethanofuran:tetrahydromethanopterin formyltransferase Energy production and conversion 20091598 Common - hypothetical protein MA2775 187 COG4139 BtuC, ABC-type cobalamin transport system, permease component Coenzyme metabolism 20092128 Common - hypothetical protein MA3313 54 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091357 Common prt extracellular protease MA2529 47 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 20090064 Common - iron ABC transporter, ATP-binding protein MA1198 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20092452 Common - amidinotransferase MA3652 25 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 20093106 Common - phycocyanin alpha phycocyanobilin lyase related protein MA4317 74 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 20089791 Common hisH imidazole glycerol phosphate synthase subunit HisH MA0913 217 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 20089449 Common - hypothetical protein MA0560 7 None None None 20090660 Nonpathogen - hypothetical protein MA1809 1 None None None 20092756 Common - ABC transporter, ATP-binding protein MA3960 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20091865 Common oppF oligopeptide ABC transporter, ATP-binding protein MA3047 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089078 Common - transcriptional regulator, MarR family MA0180 90 COG1846 MarR, Transcriptional regulators Transcription 20088922 Common znuA zinc ABC transporter, solute-binding lipoprotein MA0023 163 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 20090973 Common - hypothetical protein MA2130 52 COG2361 COG2361, Uncharacterized conserved protein Function unknown 20092722 Nonpathogen - hypothetical protein MA3926 7 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 20092770 Nonpathogen - hypothetical protein MA3976 32 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 20091594 Common - transcriptional regulator, MarR family MA2771 68 COG1846 MarR, Transcriptional regulators Transcription 20091351 Common - hypothetical protein MA2523 13 None None None 20093344 Nonpathogen - hypothetical protein MA4560 9 COG4742 COG4742, Predicted transcriptional regulator Transcription 20090387 Nonpathogen - hypothetical protein MA1528 6 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 20090161 Nonpathogen - hypothetical protein MA1297 1 COG4069 COG4069, Uncharacterized protein conserved in archaea Function unknown 20092201 Common - hypothetical protein MA3387 6 None None None 20093432 Nonpathogen - hypothetical protein MA4653 19 COG1423 COG1423, ATP-dependent DNA ligase, homolog of eukaryotic ligase III DNA replication, recombination, and repair 20092677 Common - sugar transport family protein MA3881 16 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20088929 Common - hypothetical protein MA0030 19 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092706 Nonpathogen - hypothetical protein MA3910 7 COG3366 COG3366, Uncharacterized protein conserved in archaea Function unknown 20093309 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B MA4524 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 20092994 Common hyuA hydantoinase MA4203 113 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20090752 Common isf-10 iron-sulfur flavoprotein MA1902 45 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20091789 Common mtmC monomethylamine corrinoid protein MA2971 164 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20088996 Common glyS glycyl-tRNA synthetase MA0097 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 20093289 Common - bifunctional hexulose-6-phosphate synthase/ribonuclease regulator MA4504 122 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 20091743 Nonpathogen - hypothetical protein MA2923 5 None None None 20091806 Common trpF phosphoribosylanthranilate isomerase MA2988 185 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 20089482 Nonpathogen - hypothetical protein MA0593 10 COG3612 COG3612, Uncharacterized protein conserved in archaea Function unknown 20091871 Nonpathogen - hypothetical protein MA3053 3 None None None 20089654 Common - phosphatidylethanolamine N-methyltransferase MA0769 183 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089589 Nonpathogen - hypothetical protein MA0704 4 None None None 20090217 Nonpathogen - acidic integral membrane protein MA1356 1 None None None 20090532 Common - hypothetical protein MA1680 30 COG3592 COG3592, Uncharacterized conserved protein Function unknown 20091953 Common - hypothetical protein MA3135 21 COG5658 COG5658, Predicted integral membrane protein Function unknown 20092518 Common - transposase MA3720 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 20088984 Nonpathogen cdc6 cell division control protein 6 MA0085 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 20089947 Common rpl22p 50S ribosomal protein L22P MA1077 45 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 20091076 Nonpathogen - hypothetical protein MA2236 1 None None None 20091638 Common - transcriptional regulator, CopG family MA2814 64 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 20089339 Nonpathogen - hypothetical protein MA0448 1 None None None 20091646 Common - transposase MA2822 88 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091009 Common isf-12 iron-sulfur flavoprotein MA2167 46 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20089950 Nonpathogen - ribonuclease P protein component 1 MA1080 22 COG1588 POP4, RNase P/RNase MRP subunit p29 Translation, ribosomal structure and biogenesis 20090549 Nonpathogen - hypothetical protein MA1697 8 None None None 20090778 Common - hypothetical protein MA1929 11 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 20090267 Nonpathogen - hypothetical protein MA1407 2 None None None 20092796 Nonpathogen - hypothetical protein MA4001 1 None None None 20089616 Common - hypothetical protein MA0731 2 None None None 20089830 Common - iron transport periplasmic binding protein MA0952 75 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091589 Common - transcriptional regulator, TetR family MA2766 29 COG1309 AcrR, Transcriptional regulator Transcription 20093036 Common - nucleotide binding protein MA4246 239 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 20092654 Nonpathogen - hypothetical protein MA3858 2 None None None 20092121 Common - hypothetical protein MA3306 36 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 20091881 Common cheR cheR methyltransferase MA3063 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 20090593 Nonpathogen - Imp4 family protein MA1741 8 COG2136 IMP4, Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain Translation, ribosomal structure and biogenesis / RNA processing and modification 20091910 Common - hypothetical protein MA3092 98 COG1262 COG1262, Uncharacterized conserved protein Function unknown 20091450 Common - hypothetical protein MA2627 27 COG4803 COG4803, Predicted membrane protein Function unknown 20089743 Common - hypothetical protein MA0859 170 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20092074 Nonpathogen - hypothetical protein MA3258 1 None None None 20091545 Common - hypothetical protein MA2721 222 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 20093040 Common oppB oligopeptide ABC transporter, permease protein MA4250 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089578 Common - hypothetical protein MA0693 111 COG4008 COG4008, Predicted metal-binding transcription factor Transcription 20091602 Common - hypothetical protein MA2779 92 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090463 Common pepN membrane alanine aminopeptidase MA1605 157 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 20089993 Common - ribosomal RNA adenine dimethylase MA1127 40 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090997 Nonpathogen - hypothetical protein MA2154 1 None None None 20090682 Common uppS di-trans-poly-cis-decaprenylcistransferase MA1831 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 20092255 Common - hypothetical protein MA3443 7 COG1715 Mrr, Restriction endonuclease Defense mechanisms 20092464 Nonpathogen - cell surface protein MA3664 10 COG3291 COG3291, FOG: PKD repeat General function prediction only 20093395 Common - hypothetical protein MA4611 100 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20091839 Common - sodium/calcium exchanger protein MA3021 112 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 20090560 Common - uncharacterized Fe-S protein MA1708 82 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 20092870 Common - dolichol-P-glucose synthetase MA4077 52 COG0392 COG0392, Predicted integral membrane protein Function unknown 20090567 Common - hypothetical protein MA1715 35 COG2122 COG2122, Uncharacterized conserved protein Function unknown 20089109 Nonpathogen - hypothetical protein MA0211 2 None None None 20093224 Nonpathogen - hypothetical protein MA4438 3 None None None 20089060 Common - universal stress protein MA0162 116 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20092064 Nonpathogen - hypothetical protein MA3248 2 None None None 20090569 Common slg cell surface protein MA1717 9 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20092750 Common - acetyltransferase family protein MA3954 24 COG0456 RimI, Acetyltransferases General function prediction only 20092869 Common - transcriptional regulator, ArsR family MA4076 133 COG0640 ArsR, Predicted transcriptional regulators Transcription 20089127 Nonpathogen - hypothetical protein MA0229 4 None None None 20090540 Nonpathogen - hypothetical protein MA1688 1 None None None 20091985 Common - hypothetical protein MA3167 165 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 20090234 Common - PfkB family carbohydrate kinase MA1373 165 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 20091580 Common - sensory transduction histidine kinase MA2757 140 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089242 Common - MotA/TolQ/ExbB proton channel family protein MA0344 21 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 20091496 Nonpathogen - hypothetical protein MA2675 5 None None None 20092496 Nonpathogen - 30S ribosomal protein S27ae MA3696 23 COG1998 RPS31, Ribosomal protein S27AE Translation, ribosomal structure and biogenesis 20092371 Common - hypothetical protein MA3565 128 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 20090031 Nonpathogen - hypothetical protein MA1165 3 None None None 20089697 Nonpathogen - hypothetical protein MA0813 22 COG1572 COG1572, Uncharacterized conserved protein Function unknown 20092389 Common - transcriptional regulator, TetR family MA3586 93 COG1309 AcrR, Transcriptional regulator Transcription 20093018 Common - reverse transcriptase MA4228 81 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20089475 Nonpathogen - hypothetical protein MA0586 16 COG3388 COG3388, Uncharacterized protein conserved in archaea Function unknown 20090736 Nonpathogen - hypothetical protein MA1886 1 None None None 20090145 Nonpathogen - hypothetical protein MA1281 20 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 20090980 Common - hypothetical protein MA2137 28 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089500 Nonpathogen - hypothetical protein MA0611 23 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 20090296 Nonpathogen - divalent cation transporter MA1436 10 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 20090653 Common ilvD dihydroxy-acid dehydratase MA1802 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 20091226 Nonpathogen - hypothetical protein MA2395 1 None None None 20091303 Common ybtQ iron ABC transporter MA2472 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 20092877 Nonpathogen - hypothetical protein MA4084 13 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 20089344 Common - glycosyltransferase MA0453 28 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 20090825 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A MA1977 102 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 20091399 Nonpathogen - hypothetical protein MA2573 18 COG2061 COG2061, ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase Amino acid transport and metabolism 20089716 Common fwdC formylmethanofuran dehydrogenase, subunit C MA0832 63 COG2218 FwdC, Formylmethanofuran dehydrogenase subunit C Energy production and conversion 20091547 Common thiM hydroxyethylthiazole kinase MA2723 81 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 20092625 Nonpathogen - Mcm protein MA3829 34 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 20089141 Common - hypothetical protein MA0243 51 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 20089104 Nonpathogen purP 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase MA0206 20 COG1759 COG1759, ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) General function prediction only 20089329 Common - transposase MA0437 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091557 Common - hypothetical protein MA2733 6 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20092859 Common phr deoxyribodipyrimidine photolyase MA4066 108 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 20089636 Nonpathogen - hypothetical protein MA0751 3 None None None 20092761 Common isf-18 iron-sulfur flavoprotein MA3966 40 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20092220 Common ppsA phosphoenolpyruvate synthase MA3408 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 20090175 Common - hypothetical protein MA1313 28 COG3875 COG3875, Uncharacterized conserved protein Function unknown 20091972 Common - hypothetical protein MA3154 45 COG5483 COG5483, Uncharacterized conserved protein Function unknown 20091634 Nonpathogen - hypothetical protein MA2810 1 None None None 20091904 Nonpathogen - hypothetical protein MA3086 5 None None None 20090692 Common - hypothetical protein MA1842 148 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 20090023 Common - nigerythrin MA1157 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 20090108 Common oppF oligopeptide ABC transporter, ATP-binding protein MA1244 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091370 Common - hypothetical protein MA2543 6 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 20093422 Common - hypothetical protein MA4643 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20091879 Nonpathogen flaB flagellin MA3061 9 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 20092213 Nonpathogen - hypothetical protein MA3401 1 None None None 20089522 Nonpathogen - hypothetical protein MA0635 1 None None None 20091624 Nonpathogen - hypothetical protein MA2802 1 None None None 20090456 Nonpathogen - hypothetical protein MA1598 1 None None None 20089092 Common alaS alanyl-tRNA synthetase MA0194 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20090731 Nonpathogen - hypothetical protein MA1881 1 None None None 20092597 Nonpathogen - hypothetical protein MA3801 3 None None None 20091290 Nonpathogen - hypothetical protein MA2459 2 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20089356 Common - hypothetical protein MA0465 104 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 20090083 Common vnfE nitrogenase associated protein E MA1219 68 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20090078 Common nifI1 P-II family nitrogen regulatory protein MA1214 158 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20092568 Common - hypothetical protein MA3772 11 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20092670 Common - cleavage and polyadenylation specificity factor MA3874 171 COG1782 COG1782, Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain General function prediction only 20089470 Common hemL glutamate-1-semialdehyde aminotransferase MA0581 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 20090552 Nonpathogen - hypothetical protein MA1700 1 None None None 20089099 Common leuB 3-isopropylmalate dehydrogenase MA0201 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 20089415 Common hdrD heterodisulfide reductase, subunit D MA0526 177 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 20091462 Nonpathogen - hypothetical protein MA2639 2 COG4803 COG4803, Predicted membrane protein Function unknown 20089322 Common asd aspartate-semialdehyde dehydrogenase MA0430 210 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 20090863 Nonpathogen - hypothetical protein MA2015 1 None None None 20089077 Nonpathogen tbp-2 transcription factor MA0179 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 20089565 Nonpathogen - hypothetical protein MA0680 25 COG2412 COG2412, Uncharacterized conserved protein Function unknown 20089081 Nonpathogen rpl10e 50S ribosomal protein L10e MA0183 34 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 20093095 Common - TPR-domain containing protein MA4306 190 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 20089032 Common hspA small heat shock protein MA0133 162 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 20090035 Nonpathogen - hypothetical protein MA1169 1 None None None 20091843 Common rfbA glucose-1-phosphate thymidylyltransferase MA3025 242 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 20092506 Common - Ham1 protein MA3706 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 20089487 Nonpathogen rpoN DNA-directed RNA polymerase subunit N MA0598 34 COG1644 RPB10, DNA-directed RNA polymerase, subunit N (RpoN/RPB10) Transcription 20090554 Nonpathogen - hypothetical protein MA1702 1 None None None 20091857 Common - hypothetical protein MA3039 133 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 20093152 Common - hypothetical protein MA4365 38 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 20090642 Common - hypothetical protein MA1791 24 COG4866 COG4866, Uncharacterized conserved protein Function unknown 20090651 Common - sensory transduction histidine kinase MA1800 134 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 20092503 Nonpathogen - cell surface glycoprotein MA3703 2 None None None 20093404 Nonpathogen - hypothetical protein MA4623 1 None None None 20089048 Common ramA methylamine methyltransferase corrinoid activation protein MA0150 42 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 20092118 Nonpathogen - hypothetical protein MA3303 1 None None None 20090205 Common - hypothetical protein MA1344 22 COG4895 COG4895, Uncharacterized conserved protein Function unknown 20092317 Nonpathogen - hypothetical protein MA3508 2 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 20089840 Common mat S-adenosylmethionine synthetase MA0962 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 20091004 Common - hypothetical protein MA2162 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091507 Common fabG1 3-oxoacyl-[acyl-carrier protein] reductase MA2687 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 20090337 Common hsp70 heat shock protein 70 MA1478 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 20092685 Common - aldolase MA3889 78 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 20091401 Nonpathogen - hypothetical protein MA2575 2 None None None 20089644 Common - sensory transduction histidine kinase MA0759 182 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092384 Nonpathogen - hypothetical protein MA3580 2 None None None 20090534 Common hsp60-3 Hsp60 MA1682 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 20093329 Nonpathogen - hypothetical protein MA4545 11 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 20091202 Common recG ATP-dependent DNA helicase MA2370 74 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 20090016 Nonpathogen - hypothetical protein MA1150 14 COG1617 COG1617, Uncharacterized conserved protein Function unknown 20089932 Common - polysaccharide biosynthesis protein MA1062 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20091817 Nonpathogen - hypothetical protein MA2999 1 None None None 20089312 Common - membrane protein MA0419 62 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 20090584 Nonpathogen - hypothetical protein MA1732 1 None None None 20091250 Nonpathogen - hypothetical protein MA2419 2 None None None 20090277 Nonpathogen - hypothetical protein MA1417 8 None None None 20091893 Common - 2-oxoacid ferredoxin oxidoreductase, subunit alpha MA3075 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 20092855 Common - transposase MA4062 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092710 Common - hypothetical protein MA3914 69 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 20093022 Common pepQ1 Xaa-Pro dipeptidase (cobalt-dependent) MA4232 175 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 20093239 Common - glycosyltransferase MA4453 13 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20091328 Common fumA fumarate hydratase MA2497 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 20091145 Nonpathogen - hypothetical protein MA2307 1 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 20092866 Nonpathogen - hypothetical protein MA4073 1 None None None 20091770 Common - transcriptional regulator, TetR family MA2951 63 COG1309 AcrR, Transcriptional regulator Transcription 20089887 Common cdhD acetyl-CoA decarbonylase/synthase complex subunit delta MA1012 20 COG2069 CdhD, CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) Energy production and conversion 20092783 Common aor aldehyde ferredoxin oxidoreductase MA3989 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 20091272 Common - F0F1 ATP synthase subunit beta MA2441 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 20091702 Nonpathogen - hypothetical protein MA2880 1 None None None 20090942 Common - hypothetical protein MA2097 8 None None None 20089386 Nonpathogen - hypothetical protein MA0497 1 None None None 20089536 Common - hypothetical protein MA0649 94 COG1262 COG1262, Uncharacterized conserved protein Function unknown 20091091 Common - hypothetical protein MA2252 41 COG3326 COG3326, Predicted membrane protein Function unknown 20091173 Nonpathogen - acetyltransferase (GNAT) family protein MA2338 1 COG0456 RimI, Acetyltransferases General function prediction only 20092908 Nonpathogen - hypothetical protein MA4115 19 COG2117 COG2117, Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 20093331 Nonpathogen - methyl coenzyme M reductase, subunit gamma MA4547 14 COG4057 McrG, Methyl coenzyme M reductase, gamma subunit Coenzyme metabolism 20089135 Nonpathogen - hypothetical protein MA0237 1 None None None 20092227 Nonpathogen - hypothetical protein MA3415 2 None None None 20092601 Common - hypothetical protein MA3805 12 COG5280 COG5280, Phage-related minor tail protein Function unknown 20091532 Nonpathogen - hypothetical protein MA2708 1 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 20092522 Nonpathogen - hypothetical protein MA3725 1 None None None 20093324 Common - hypothetical protein MA4540 79 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 20092246 Common - transposase MA3434 88 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089560 Common pycA pyruvate carboxylase subunit A MA0675 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 20090259 Nonpathogen - hypothetical protein MA1398 1 None None None 161484943 Common - aconitate hydratase MA0250 222 COG1048 AcnA, Aconitase A Energy production and conversion 20090252 Common - hypothetical protein MA1391 97 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 20092058 Common deoA thymidine phosphorylase MA3242 147 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 20092182 Common - sensory transduction histidine kinase MA3368 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20090705 Common - hypothetical protein MA1855 114 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 20092833 Nonpathogen - hypothetical protein MA4040 29 COG1709 COG1709, Predicted transcriptional regulator Transcription 20090987 Common - carbamoyl phosphate synthase small subunit MA2144 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 20091576 Nonpathogen - hypothetical protein MA2753 3 None None None 20089409 Common cbiE cobalt-precorrin-6Y C(5)-methyltransferase MA0520 71 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 20090619 Nonpathogen - hypothetical protein MA1768 5 COG1572 COG1572, Uncharacterized conserved protein Function unknown 20090002 Common hypE hydrogenase expression/formation protein MA1136 195 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 20091685 Common - response regulator receiver MA2861 204 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 20093410 Common - D-lactate dehydrogenase MA4631 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 20092826 Common - surface antigen gene MA4033 77 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20091627 Nonpathogen - hypothetical protein MA2805 1 None None None 20090948 Nonpathogen - hypothetical protein MA2104 1 None None None 20091750 Nonpathogen - transposase MA2931 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089007 Common - glyoxalase MA0108 9 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 20091567 Nonpathogen - hypothetical protein MA2744 1 None None None 20090421 Nonpathogen - hypothetical protein MA1563 1 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 20092332 Common - hypothetical protein MA3524 33 COG1395 COG1395, Predicted transcriptional regulator Transcription 20092104 Common lonB endopeptidase La MA3289 201 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 20092478 Nonpathogen - hypothetical protein MA3678 2 None None None 20093362 Nonpathogen - hypothetical protein MA4578 1 None None None 20090118 Nonpathogen - hypothetical protein MA1254 1 None None None 20090910 Common - hypothetical protein MA2063 13 None None None 20092647 Common - Dhh protein MA3851 45 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 20091216 Nonpathogen - hypothetical protein MA2385 1 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 20089421 Nonpathogen mtbB dimethylamine methyltransferase MA0532 1 None None None 20089671 Common glnP glutamine ABC transporter, permease protein MA0787 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 20090990 Common proX glycine betaine/L-proline ABC transporter, solute-binding protein MA2147 67 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 20093127 Common - acetyltransferase MA4339 96 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 20091759 Nonpathogen - transposase MA2940 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093030 Common - hypothetical protein MA4240 30 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 20093197 Common - hypothetical protein MA4410 194 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 20090270 Nonpathogen - hypothetical protein MA1410 1 None None None 20090090 Common nifV homocitrate synthase MA1226 189 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 20092037 Common - hypothetical protein MA3221 19 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20091310 Common - peptide ABC transporter, ATP-binding protein MA2479 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089881 Common fur ferric uptake regulation protein MA1005 186 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 20089203 Common fmdF formylmethanofuran dehydrogenase, subunit F MA0305 153 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 20091934 Nonpathogen - hypothetical protein MA3116 1 None None None 20090168 Common - hypothetical protein MA1304 10 None None None 20092390 Common - small heat shock protein, class I MA3589 136 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 20092072 Nonpathogen - hypothetical protein MA3256 1 None None None 20091403 Nonpathogen - hypothetical protein MA2577 1 None None None 20092327 Common folD methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase MA3519 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 20091059 Common - potassium channel protein MA2218 77 COG4325 COG4325, Predicted membrane protein Function unknown 20091931 Nonpathogen - hypothetical protein MA3113 9 None None None 20090392 Common istB IstB helper protein MA1533 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090610 Nonpathogen - hypothetical protein MA1759 1 None None None 20093001 Nonpathogen - hypothetical protein MA4210 1 None None None 20092043 Nonpathogen - hypothetical protein MA3227 1 None None None 20088944 Nonpathogen - hypothetical protein MA0045 1 None None None 20093417 Common - RNA 2'-phosphotransferase-like protein MA4638 41 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 20091396 Common - GTP-binding protein MA2570 93 COG0218 COG0218, Predicted GTPase General function prediction only 20089926 Common - hypothetical protein MA1055 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20093269 Nonpathogen - hypothetical protein MA4484 12 COG4189 COG4189, Predicted transcriptional regulator Transcription 20093351 Common mrpF putative monovalent cation/H+ antiporter subunit F MA4567 45 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 20090697 Common hemU iron(III) ABC transporter, permease MA1847 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20088978 Common - hypothetical protein MA0079 63 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 20092762 Common - methylcoenzyme M reductase system, component A2 MA3967 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20092051 Common - hypothetical protein MA3235 41 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 20093353 Common mrpD putative monovalent cation/H+ antiporter subunit D MA4569 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 20091447 Common - hypothetical protein MA2621 3 None None None 20089886 Common cdhE acetyl-CoA decarbonylase/synthase complex subunit gamma MA1011 23 COG1456 CdhE, CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) Energy production and conversion 20092555 Common - mannosyltransferase B MA3757 231 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20092533 Nonpathogen - hypothetical protein MA3735 10 COG4855 COG4855, Uncharacterized protein conserved in archaea Function unknown 20089154 Nonpathogen - hypothetical protein MA0256 1 None None None 20093302 Common - hypothetical protein MA4517 68 COG1469 COG1469, Uncharacterized conserved protein Function unknown 20092987 Common - 6-pyruvoyltetrahydropterin synthase MA4196 72 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 20090507 Common pfpI intracellular protease MA1654 156 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 20092169 Common - hypothetical protein MA3355 29 None None None 20089442 Nonpathogen - hypothetical protein MA0553 1 None None None 20089837 Common nadA quinolinate synthetase MA0959 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 20089914 Common - hypothetical protein MA1042 6 None None None 20092634 Nonpathogen - hypothetical protein MA3838 1 None None None 20093181 Common - hypothetical protein MA4394 149 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 20089116 Common hisA N-(5-phospho-D-ribosylformimino)-5-amino-1-(5-phosphoribosyl)-4-imidazole carboxamide isomerase MA0218 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 20090396 Common - hypothetical protein MA1537 19 COG1470 COG1470, Predicted membrane protein Function unknown 20092436 Nonpathogen - hypothetical protein MA3636 1 None None None 20092886 Common - hypothetical protein MA4093 186 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 20089752 Common - multidrug ABC transporter, ATP-binding protein MA0868 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20093053 Common - isopropylmalate/homocitrate/citramalate synthase family protein MA4264 190 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 20091237 Common - transposase MA2406 68 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091365 Common mitM methyltransferase MA2537 135 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20093076 Common - cell surface protein MA4287 102 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090724 Common malP phosphorylase MA1874 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 20089228 Common - NADPH nitroreductase (oxygen-insensitive) MA0330 103 COG0778 NfnB, Nitroreductase Energy production and conversion 20090500 Nonpathogen - hypothetical protein MA1647 1 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 20090764 Common dppA dipeptide ABC transporter, solute-binding protein MA1915 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20089775 Common phoU phosphate transport system regulatory protein MA0891 199 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 20089000 Common - hypothetical protein MA0101 52 COG2361 COG2361, Uncharacterized conserved protein Function unknown 20091779 Common - proton/sodium-glutamate symporter MA2961 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 20089055 Common - hypothetical protein MA0157 41 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 20091277 Common - hypothetical protein MA2446 70 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 20091998 Nonpathogen - hypothetical protein MA3180 1 None None None 20093113 Common - hypothetical protein MA4325 24 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 161484937 Common - FO synthase subunit 2 MA1489 101 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 20091711 Common - hydantoinase/oxoprolinase MA2889 119 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20088932 Common porD pyruvate synthase, subunit delta MA0033 68 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 20093260 Nonpathogen - hypothetical protein MA4475 2 None None None 20092266 Common - hypothetical protein MA3454 50 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089901 Common - hypothetical protein MA1026 12 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090756 Nonpathogen - hypothetical protein MA1907 2 None None None 20091482 Nonpathogen - hypothetical protein MA2659 1 None None None 20089503 Common - 3-hydroxyisobutyrate dehydrogenase MA0614 180 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 20092195 Common fprA flavoprotein MA3381 91 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 20089253 Nonpathogen - hypothetical protein MA0355 1 None None None 20091737 Nonpathogen - hypothetical protein MA2917 2 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 20092675 Common hppA membrane-bound proton-translocating pyrophosphatase MA3879 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 20089567 Common - SpoU rRNA methylase MA0682 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 20089403 Nonpathogen - hypothetical protein MA0514 1 None None None 20092557 Common - transposase MA3759 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091050 Common trkH Trk potassium uptake system protein, transmembrane component H MA2209 138 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 20089853 Common frhD hydrogenase maturation protease MA0976 45 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 20089801 Nonpathogen - 30S ribosomal protein S8e MA0923 34 COG2007 RPS8A, Ribosomal protein S8E Translation, ribosomal structure and biogenesis 20089107 Common trmL N2-methylguanosine tRNA methyltransferase MA0209 44 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 20090200 Common - hypothetical protein MA1339 143 COG1733 COG1733, Predicted transcriptional regulators Transcription 20091476 Common - aminoacyl-histidine dipeptidase MA2653 57 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 20092363 Nonpathogen - hypothetical protein MA3556 8 None None None 20090986 Common carB carbamoyl phosphate synthase large subunit MA2143 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 20089023 Nonpathogen - hypothetical protein MA0124 1 None None None 20089346 Nonpathogen mtaB1 methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 1 MA0455 6 None None None 20090961 Common - hypothetical protein MA2118 22 COG4268 McrC, McrBC 5-methylcytosine restriction system component Defense mechanisms 20090991 Common fecC Fe(III) dicitrate ABC transporter, permease MA2148 112 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20093385 Common oppA oligopeptide ABC transporter, solute-binding protein MA4601 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20091353 Common - WD40-repeat containing protein MA2525 102 COG2319 COG2319, FOG: WD40 repeat General function prediction only 20089306 Common - hypothetical protein MA0413 18 COG4925 COG4925, Uncharacterized conserved protein Function unknown 20091282 Common - hypothetical protein MA2451 121 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 20092896 Common ahpC peroxiredoxin MA4103 221 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 20092355 Common - hypothetical protein MA3548 41 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 20091453 Common adh alcohol dehydrogenase MA2630 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 20089761 Common - magnesium-chelatase subunit MA0877 100 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 20090907 Nonpathogen - hypothetical protein MA2060 2 None None None 20091928 Nonpathogen - hypothetical protein MA3110 1 None None None 20092282 Nonpathogen - hypothetical protein MA3469 1 None None None 20091048 Common - hypothetical protein MA2207 39 COG1378 COG1378, Predicted transcriptional regulators Transcription 20090156 Common - cell surface protein MA1292 50 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092111 Nonpathogen - hypothetical protein MA3296 3 None None None 20090791 Nonpathogen - hypothetical protein MA1942 1 None None None 20092401 Nonpathogen - hypothetical protein MA3600 2 None None None 20089277 Nonpathogen - hypothetical protein MA0380 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 20092408 Common isf-15 iron-sulfur flavoprotein MA3608 66 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20090783 Common - hypothetical protein MA1934 15 COG1567 COG1567, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 20089256 Common - hypothetical protein MA0359 40 COG1378 COG1378, Predicted transcriptional regulators Transcription 20090792 Common - hypothetical protein MA1943 165 COG0457 NrfG, FOG: TPR repeat General function prediction only 20090915 Nonpathogen - hypothetical protein MA2069 1 None None None 20093120 Common - hypothetical protein MA4332 111 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 20090743 Nonpathogen - hypothetical protein MA1893 1 None None None 20092146 Common - hypothetical protein MA3332 8 None None None 20089759 Nonpathogen - hypothetical protein MA0875 1 None None None 20090524 Nonpathogen - hypothetical protein MA1671 10 COG4738 COG4738, Predicted transcriptional regulator Transcription 20093201 Nonpathogen - hypothetical protein MA4414 8 COG1935 COG1935, Uncharacterized conserved protein Function unknown 20089304 Common - hypothetical protein MA0411 5 None None None 20089362 Nonpathogen - hypothetical protein MA0473 1 None None None 20092966 Nonpathogen - hypothetical protein MA4173 1 None None None 20093319 Common - hypothetical protein MA4534 91 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 20089122 Nonpathogen - hypothetical protein MA0224 12 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 20092295 Nonpathogen - MutT protein MA3484 2 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 20093232 Common - hypothetical protein MA4446 134 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20089267 Nonpathogen - hypothetical protein MA0370 3 None None None 20089815 Common sufC ABC transporter, ATP-binding protein MA0937 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 20093212 Common - MotA/TolQ/ExbB proton channel family protein MA4426 21 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 20090605 Common - cell surface protein MA1753 52 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089265 Common - transcriptional regulator, TetR family MA0368 129 COG1309 AcrR, Transcriptional regulator Transcription 20091815 Nonpathogen - hypothetical protein MA2997 1 None None None 20092694 Common nifD nitrogenase, subunit alpha MA3898 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20090135 Common - hypothetical protein MA1271 11 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 20093154 Common ribD 5-amino-6-(5-phosphoribosylamino) uracil reductase MA4367 18 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 20093297 Common - acetyltransferase (GNAT) family protein MA4512 14 COG3393 COG3393, Predicted acetyltransferase General function prediction only 20093132 Common smtB efflux system transcriptional regulator, ArsR family MA4344 149 COG0640 ArsR, Predicted transcriptional regulators Transcription 20091672 Nonpathogen - hypothetical protein MA2847 2 None None None 20090505 Common - dihydrolipoamide dehydrogenase MA1652 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 20090212 Nonpathogen eif1A translation initiation factor IF-1A MA1351 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 20089538 Common - hypothetical protein MA0651 56 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 20092639 Nonpathogen - hypothetical protein MA3843 2 None None None 20090837 Common - hypothetical protein MA1989 158 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 20091722 Nonpathogen - hypothetical protein MA2901 3 COG4740 COG4740, Predicted metalloprotease General function prediction only 20092843 Common - glucan 1,4-alpha-glucosidase MA4050 39 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 20091732 Common vorC 2-oxoisovalerate ferredoxin oxidoreductase, gamma subunit MA2911 28 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 20092810 Common - hypothetical protein MA4016 220 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092167 Common istB IstB helper protein MA3353 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20089378 Nonpathogen - hypothetical protein MA0489 1 None None None 20089443 Nonpathogen - hypothetical protein MA0554 1 None None None 20089399 Nonpathogen - hypothetical protein MA0510 1 None None None 20091435 Nonpathogen - hypothetical protein MA2609 1 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 20093086 Common - cell surface protein MA4297 122 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20092954 Common hypF hydrogenase expression/formation regulatory protein MA4161 113 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 20092951 Common atpA V-type ATP synthase subunit A MA4158 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 20091822 Common - hypothetical protein MA3004 6 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20091491 Nonpathogen - hypothetical protein MA2668 1 None None None 20091195 Common - hypothetical protein MA2362 57 COG4717 COG4717, Uncharacterized conserved protein Function unknown 20092106 Nonpathogen - hypothetical protein MA3291 1 None None None 20089968 Common camH carbonate dehydratase MA1098 154 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 20092481 Nonpathogen - hypothetical protein MA3681 1 None None None 20093129 Common - membrane associated ATPase MA4341 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 20090327 Common - response regulator receiver MA1468 218 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 20092025 Nonpathogen - hypothetical protein MA3209 2 None None None 20093208 Common - bacteriochlorophyll synthase 43 kDa subunit MA4421 88 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 20089846 Common - orotidine-5-phosphate decarboxylase MA0969 162 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 20090805 Common - sensory transduction histidine kinase MA1957 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20090833 Nonpathogen - hypothetical protein MA1985 6 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 20092022 Common - hypothetical protein MA3206 41 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 20090953 Common - multidrug ABC transporter, permease protein MA2109 205 COG1511 COG1511, Predicted membrane protein Function unknown 20089330 Nonpathogen - hypothetical protein MA0438 1 None None None 20091066 Nonpathogen - hypothetical protein MA2226 1 None None None 20093068 Common - coenzyme PQQ synthesis protein E MA4279 111 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20091864 Common oppD oligopeptide ABC transporter, ATP-binding protein MA3046 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089825 Nonpathogen - hypothetical protein MA0947 2 None None None 20090130 Nonpathogen rpoH DNA-directed RNA polymerase subunit H MA1266 33 COG2012 RPB5, DNA-directed RNA polymerase, subunit H, RpoH/RPB5 Transcription 20089704 Common - hypothetical protein MA0820 21 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 20091162 Nonpathogen - hypothetical protein MA2327 1 None None None 20093248 Common - hypothetical protein MA4462 32 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090123 Common rps12P 30S ribosomal protein S12P MA1259 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 20093431 Common - hypothetical protein MA4652 74 COG2013 COG2013, Uncharacterized conserved protein Function unknown 20089666 Common - acetyltransferase (GNAT) family protein MA0782 25 None None None 20089496 Nonpathogen - hypothetical protein MA0607 1 None None None 20089293 Nonpathogen - hypothetical protein MA0398 1 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 20090696 Nonpathogen - hypothetical protein MA1846 1 None None None 20091055 Common - permease MA2214 166 COG0628 PerM, Predicted permease General function prediction only 20093170 Nonpathogen - hypothetical protein MA4383 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 20088912 Common cheR cheR methyltransferase MA0013 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 20092463 Nonpathogen - hypothetical protein MA3663 1 None None None 20091524 Common - hypothetical protein MA2700 9 None None None 20091028 Nonpathogen - transposase MA2187 2 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091718 Common - hypothetical protein MA2897 48 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 20092584 Nonpathogen - hypothetical protein MA3788 2 None None None 20088907 Common traB TraB family protein MA0008 39 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 20088939 Nonpathogen - hypothetical protein MA0040 33 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 20090921 Common - hypothetical protein MA2075 48 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 20089392 Nonpathogen - hypothetical protein MA0503 1 None None None 20091232 Common - hypothetical protein MA2401 30 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 20089465 Common cysG uroporphyrin-III C-methyltransferase MA0576 122 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 20091797 Common - cell surface protein MA2979 45 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20092793 Common - ABC transporter, ATP-binding protein MA3998 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20091136 Nonpathogen - hypothetical protein MA2298 1 None None None 20093378 Common aroE shikimate 5-dehydrogenase MA4594 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 20091410 Nonpathogen - hypothetical protein MA2584 1 None None None 20092475 Nonpathogen - hypothetical protein MA3675 2 None None None 20091012 Common - glycosyltransferase MA2170 211 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 20089783 Nonpathogen - hypothetical protein MA0904 7 None None None 20091373 Nonpathogen - hypothetical protein MA2546 4 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 20092585 Common - nitroreductase MA3789 122 COG0778 NfnB, Nitroreductase Energy production and conversion 20092779 Nonpathogen - hypothetical protein MA3985 1 None None None 20091032 Common isf-13 iron-sulfur flavoprotein MA2191 45 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20089738 Common - N-acetyltransferase MA0854 61 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 20092934 Nonpathogen - hypothetical protein MA4141 1 None None None 20090119 Common rps10p 30S ribosomal protein S10P MA1255 105 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 20090260 Nonpathogen - hypothetical protein MA1399 1 None None None 20090415 Nonpathogen - hypothetical protein MA1557 1 None None None 20092923 Nonpathogen - hypothetical protein MA4130 1 None None None 20091484 Common - hypothetical protein MA2661 5 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 20091676 Nonpathogen - hypothetical protein MA2852 1 None None None 20090239 Nonpathogen aroL shikimate kinase MA1378 27 COG1685 COG1685, Archaeal shikimate kinase Amino acid transport and metabolism / Coenzyme metabolism 20093312 Common - hypothetical protein MA4527 120 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090968 Nonpathogen - hypothetical protein MA2125 1 None None None 20089456 Nonpathogen - hypothetical protein MA0567 2 None None None 20093045 Common - c-type cytochrome biogenesis protein MA4255 177 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 20092663 Nonpathogen - hypothetical protein MA3867 2 None None None 20091098 Nonpathogen - hypothetical protein MA2259 1 None None None 20091725 Common - hypothetical protein MA2904 34 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20089174 Nonpathogen mtrE tetrahydromethanopterin S-methyltransferase subunit E MA0276 14 COG4059 MtrE, Tetrahydromethanopterin S-methyltransferase, subunit E Coenzyme metabolism 20090591 Common - sensory transduction histidine kinase MA1739 222 COG3322 COG3322, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 20091696 Nonpathogen - hypothetical protein MA2874 3 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 20092719 Nonpathogen - hypothetical protein MA3923 2 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 20093280 Nonpathogen - hypothetical protein MA4495 1 None None None 20090648 Nonpathogen - hypothetical protein MA1797 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 20090405 Common - hypothetical protein MA1547 49 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20090410 Nonpathogen - hypothetical protein MA1552 6 None None None 20089288 Nonpathogen - hypothetical protein MA0391 1 None None None 20090886 Nonpathogen - hypothetical protein MA2039 1 None None None 20092431 Common cbiX sirohydrochlorin cobaltochelatase MA3631 63 COG2138 COG2138, Uncharacterized conserved protein Function unknown 20089615 Nonpathogen - hypothetical protein MA0730 2 None None None 20092741 Common - sodium bile acid symporter family protein MA3945 131 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 20093177 Nonpathogen - hypothetical protein MA4390 1 None None None 20091417 Nonpathogen - hypothetical protein MA2591 1 None None None 20090929 Common - cob(I)alamin adenosyltransferase MA2084 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 20092013 Common thiD phosphomethylpyrimidine kinase MA3197 223 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 20089281 Common cobN cobaltochelatase MA0384 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20090716 Common - hypothetical protein MA1866 54 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 20089046 Common - ribosomal RNA adenine dimethylase MA0148 79 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20091847 Common - ATPase, AAA family MA3029 249 COG1223 COG1223, Predicted ATPase (AAA+ superfamily) General function prediction only 20090061 Common - hypothetical protein MA1195 20 COG3291 COG3291, FOG: PKD repeat General function prediction only 20091148 Common adeC adenine deaminase MA2310 69 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 20091248 Common - hypothetical protein MA2417 75 COG1479 COG1479, Uncharacterized conserved protein Function unknown 20091019 Nonpathogen - hypothetical protein MA2177 1 None None None 20089183 Nonpathogen - hypothetical protein MA0285 13 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20092257 Common - hypothetical protein MA3445 163 COG1162 COG1162, Predicted GTPases General function prediction only 20091181 Common - hypothetical protein MA2346 40 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 20089770 Nonpathogen - hypothetical protein MA0886 1 None None None 20092429 Nonpathogen - hypothetical protein MA3629 1 None None None 20089627 Nonpathogen - hypothetical protein MA0742 1 None None None 20089754 Common - ABC transporter, ATP-binding protein MA0870 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 20090893 Nonpathogen - hypothetical protein MA2046 28 COG1650 COG1650, Uncharacterized protein conserved in archaea Function unknown 20092981 Nonpathogen - hypothetical protein MA4190 8 COG4004 COG4004, Uncharacterized protein conserved in archaea Function unknown 20092347 Nonpathogen - hypothetical protein MA3540 1 None None None 20091167 Nonpathogen - hypothetical protein MA2332 2 None None None 20089523 Common aspC aspartate aminotransferase MA0636 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 20089320 Common - AIR carboxylase MA0428 64 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 20093346 Common hyuA hydantoinase MA4562 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20089865 Nonpathogen - hypothetical protein MA0988 3 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 20091945 Common hdrC heterodisulfide reductase, subunit C MA3127 37 COG1150 HdrC, Heterodisulfide reductase, subunit C Energy production and conversion 20090857 Common bla beta-lactamase MA2009 20 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 20092150 Nonpathogen - hypothetical protein MA3336 4 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20089327 Nonpathogen - hypothetical protein MA0435 2 None None None 20091677 Common - hypothetical protein MA2853 5 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 20088958 Common - hypothetical protein MA0059 28 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 20090844 Common - hypothetical protein MA1996 68 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 20091425 Nonpathogen - phage integrase MA2599 1 None None None 20092806 Nonpathogen - hypothetical protein MA4011 11 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089798 Nonpathogen - hypothetical protein MA0920 31 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 20089552 Nonpathogen - hypothetical protein MA0665 11 COG4818 COG4818, Predicted membrane protein Function unknown 20092303 Nonpathogen - hypothetical protein MA3493 1 None None None 20089982 Nonpathogen - transposase MA1116 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092978 Common - transposase MA4186 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091292 Nonpathogen - hypothetical protein MA2461 2 None None None 20093161 Common - hypothetical protein MA4374 176 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20093274 Nonpathogen - hypothetical protein MA4489 2 None None None 20090677 Nonpathogen - hypothetical protein MA1826 7 COG1504 COG1504, Uncharacterized conserved protein Function unknown 20091335 Nonpathogen - hypothetical protein MA2504 1 None None None 20091610 Nonpathogen - hypothetical protein MA2787 1 None None None 20091155 Common - hypothetical protein MA2319 13 COG4198 COG4198, Uncharacterized conserved protein Function unknown 20092066 Common - cobyric acid synthase MA3250 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 20091255 Common mtbC dimethylamine corrinoid protein MA2424 171 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20089974 Common - H/ACA RNA-protein complex component Cbf5p MA1105 238 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 20092656 Common cdhA acetyl-CoA decarbonylase/synthase complex subunit alpha MA3860 21 COG1152 CdhA, CO dehydrogenase/acetyl-CoA synthase alpha subunit Energy production and conversion 20090366 Nonpathogen fpoO F(420)H(2) dehydrogenase, subunit FpoO MA1507 2 None None None 20091642 Common - hypothetical protein MA2818 22 COG3603 COG3603, Uncharacterized conserved protein Function unknown 20090381 Nonpathogen rps28e 30S ribosomal protein S28e MA1522 33 COG2053 RPS28A, Ribosomal protein S28E/S33 Translation, ribosomal structure and biogenesis 20092735 Common - hypothetical protein MA3939 21 COG4273 COG4273, Uncharacterized conserved protein Function unknown 20089809 Common mttC trimethylamine corrinoid protein MA0931 165 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20089930 Common - transposase MA1060 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20090442 Common gyrB DNA topoisomerase (ATP-hydrolyzing), subunit B MA1584 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 20089620 Common paaI phenylacetic acid degradation protein MA0735 32 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 20091794 Nonpathogen - hypothetical protein MA2976 2 None None None 20089987 Common - integral membrane protein MA1121 146 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 20090813 Nonpathogen - hypothetical protein MA1965 1 None None None 20091223 Nonpathogen - hypothetical protein MA2392 1 None None None 20091791 Nonpathogen - hypothetical protein MA2973 5 None None None 20092440 Common - iron ABC transporter, solute-binding protein MA3640 82 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091344 Common - hypothetical protein MA2514 14 COG4739 COG4739, Uncharacterized protein containing a ferredoxin domain Function unknown 20092837 Nonpathogen cyaB adenylate cyclase MA4044 32 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 20093168 Common - hypothetical protein MA4381 122 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 20089052 Common bioB biotin synthase MA0154 119 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 20091890 Nonpathogen - hypothetical protein MA3072 1 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 20090479 Common - hypothetical protein MA1624 18 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 20091587 Common - transcriptional regulator, TetR family MA2764 92 COG1309 AcrR, Transcriptional regulator Transcription 20088900 Nonpathogen cdc6 cell division control protein 6 MA0001 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 20091240 Common - hypothetical protein MA2409 38 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 20091769 Nonpathogen - hypothetical protein MA2950 2 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 20092171 Common fecE iron(III) ABC transporter, ATP-binding protein MA3357 47 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091348 Common pyrE orotate phosphoribosyltransferase MA2520 44 COG0856 COG0856, Orotate phosphoribosyltransferase homologs Nucleotide transport and metabolism 20092134 Nonpathogen - hypothetical protein MA3320 3 None None None 20090542 Nonpathogen - hypothetical protein MA1690 1 None None None 20092546 Common leuB 3-isopropylmalate dehydrogenase MA3748 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 20090579 Common iorA indolepyruvate ferredoxin oxidoreductase, subunit alpha MA1727 127 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 20089163 Common - hypothetical protein MA0265 51 COG1371 COG1371, Uncharacterized conserved protein Function unknown 20092794 Common - hypothetical protein MA3999 113 COG4087 COG4087, Soluble P-type ATPase General function prediction only 20090728 Common - sensory transduction histidine kinase MA1878 160 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090195 Common hprA glycerate dehydrogenase MA1334 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 20092417 Common - hypothetical protein MA3617 44 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 20089991 Nonpathogen - transposase MA1125 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092562 Common - polysaccharide biosynthesis protein MA3764 64 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 20093142 Common cmtM methylcobamide:CoM methyltransferase isozyme M MA4355 31 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20089631 Common - hypothetical protein MA0746 177 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 20089477 Common - cell surface protein MA0588 32 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20089119 Nonpathogen - hypothetical protein MA0221 5 None None None 20089143 Common - hypothetical protein MA0245 39 COG1679 COG1679, Uncharacterized conserved protein Function unknown 20091571 Common - transposase MA2748 42 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090874 Nonpathogen - hypothetical protein MA2026 1 None None None 20091498 Common - hypothetical protein MA2677 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 20091641 Common - sodium/calcium exchanger protein MA2817 106 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 20092105 Common - hypothetical protein MA3290 23 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 20092053 Common aroK shikimate kinase MA3237 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 20089201 Common - hypothetical protein MA0303 213 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089216 Common - hypothetical protein MA0318 56 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 20092322 Common metF 5,10-methylenetetrahydrofolate reductase (FADH) MA3514 69 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 20090116 Common - haloacid dehalogenase-like hydrolase family protein MA1252 101 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 20092842 Nonpathogen - hypothetical protein MA4049 1 None None None 20089927 Nonpathogen - hypothetical protein MA1056 4 None None None 20091996 Common - rhodanese family protein MA3178 122 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 20089532 Nonpathogen rps27e 30S ribosomal protein S27e MA0645 34 COG2051 RPS27A, Ribosomal protein S27E Translation, ribosomal structure and biogenesis 20091936 Common - surface antigen gene MA3118 79 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20091334 Common varS transmembrane efflux protein MA2503 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20092081 Common nifU nitrogen fixation protein MA3265 150 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 20091275 Common - hypothetical protein MA2444 63 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 20092357 Common - hypothetical protein MA3550 25 COG2155 COG2155, Uncharacterized conserved protein Function unknown 20093115 Nonpathogen - hypothetical protein MA4327 10 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 20091174 Common - hypothetical protein MA2339 9 None None None 20093419 Nonpathogen - hypothetical protein MA4640 7 COG4827 COG4827, Predicted transporter General function prediction only 20089673 Common - hypothetical protein MA0789 247 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 20091916 Nonpathogen - hypothetical protein MA3098 25 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 20091007 Nonpathogen - hypothetical protein MA2165 1 None None None 20092148 Common - hypothetical protein MA3334 8 None None None 20090196 Nonpathogen - hypothetical protein MA1335 1 None None None 20091504 Nonpathogen - hypothetical protein MA2684 4 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 20089768 Nonpathogen - hypothetical protein MA0884 3 None None None 20089359 Nonpathogen - hypothetical protein MA0470 1 None None None 20089909 Nonpathogen - transposase MA1034 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092563 Common - hypothetical protein MA3765 20 COG2327 WcaK, Uncharacterized conserved protein Function unknown 20091636 Nonpathogen - hypothetical protein MA2812 1 None None None 20089786 Common - phosphoribosyl-AMP cyclohydrolase MA0908 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 20091883 Common cheC1 chemotaxis protein CheC MA3065 39 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 20091804 Common trpG anthranilate synthase, component II MA2986 241 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 20090021 Nonpathogen - hypothetical protein MA1155 5 None None None 20091604 Common - hypothetical protein MA2781 133 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20093412 Common - acetyltransferase (GNAT) family protein MA4633 113 COG0456 RimI, Acetyltransferases General function prediction only 20089401 Common - surface antigen gene MA0512 80 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20091001 Nonpathogen - hypothetical protein MA2159 3 None None None 20091312 Common - peptide ABC transporter, permease protein MA2481 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20090433 Nonpathogen - hypothetical protein MA1575 5 COG5485 COG5485, Predicted ester cyclase General function prediction only 20093373 Common - cell surface protein MA4589 122 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089903 Common - long-chain fatty-acid-CoA ligase MA1028 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20093074 Common - cell surface protein MA4285 125 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092899 Common - hypothetical protein MA4106 26 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 20091895 Nonpathogen flaB flagellin MA3077 7 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 20092324 Common dhpS dihydropteroate synthase MA3516 216 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 20090573 Common corA magnesium Mg(2+)/cobalt Co(2+) transport protein MA1721 186 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 20091390 Common - hypothetical protein MA2564 19 None None None 20089972 Nonpathogen - integral membrane protein MA1103 22 COG1422 COG1422, Predicted membrane protein Function unknown 20092768 Common - hypothetical protein MA3974 16 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 20091293 Common icaA glucosaminyltransferase MA2462 229 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20090096 Common - iron(III) ABC transporter, solute-binding protein MA1232 81 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20089537 Nonpathogen - hypothetical protein MA0650 6 None None None 20091852 Common hemD uroporphyrinogen-III synthase MA3034 86 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 20089755 Nonpathogen - hypothetical protein MA0871 1 None None None 20092084 Common rimK ribosomal protein S6 modification protein MA3268 102 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 20093402 Common emrB multidrug resistance protein MA4621 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20089006 Common gno gluconate 5-dehydrogenase MA0107 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 20091254 Common - hypothetical protein MA2423 5 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 20089605 Common - hypothetical protein MA0720 25 COG1096 COG1096, Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) Translation, ribosomal structure and biogenesis 20089509 Nonpathogen - hypothetical protein MA0621 2 None None None 20089920 Common istB IstB helper protein MA1049 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20093209 Common - moaA/nifB/pqqE family protein MA4422 155 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20090333 Common - hypothetical protein MA1474 24 COG1548 COG1548, Predicted transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 20090550 Nonpathogen - hypothetical protein MA1698 3 None None None 20092789 Common - BadF/BadG/BcrA/BcrD ATPase MA3994 64 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 20089629 Nonpathogen - hypothetical protein MA0744 4 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 20090211 Nonpathogen - hypothetical protein MA1350 1 None None None 20090464 Common - hypothetical protein MA1606 18 COG4828 COG4828, Predicted membrane protein Function unknown 20090055 Common - TrpR binding protein WrbA MA1189 109 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20090240 Nonpathogen - integrase core domain MA1379 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089223 Common modA molybdenum ABC transporter, solute-binding protein MA0325 91 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 20091124 Common - amino acid transporter MA2286 157 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 20089202 Nonpathogen fmdE formylmethanofuran dehydrogenase, subunit E MA0304 15 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 20091409 Nonpathogen - hypothetical protein MA2583 2 None None None 20091704 Common - hypothetical protein MA2882 24 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 20092315 Common istB IstB helper protein MA3505 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20088946 Nonpathogen - hypothetical protein MA0047 2 None None None 20089383 Nonpathogen - hypothetical protein MA0494 1 None None None 20092780 Common - agmatinase MA3986 159 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 20092752 Common deaD ATP-dependent RNA helicase MA3956 243 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 20090274 Nonpathogen - hypothetical protein MA1414 11 None None None 20092903 Nonpathogen pfdA prefoldin subunit alpha MA4110 17 COG1730 GIM5, Predicted prefoldin, molecular chaperone implicated in de novo protein folding Posttranslational modification, protein turnover, chaperones 20092649 Common ftsA coenzyme F390 synthetase MA3853 135 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 20093051 Common cbiL cobalt-precorrin-2 C(20)-methyltransferase MA4262 105 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 20090629 Nonpathogen - hypothetical protein MA1778 34 COG1500 COG1500, Predicted exosome subunit Translation, ribosomal structure and biogenesis 20092188 Common - hypothetical protein MA3374 20 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20092460 Common - iron-sulfur cluster binding protein MA3660 135 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 20091845 Nonpathogen - hypothetical protein MA3027 1 None None None 20091411 Nonpathogen - hypothetical protein MA2585 1 None None None 20092996 Common - antibiotic resistance ABC transporter permease protein MA4205 174 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 20090202 Common - Fmn-binding protein MA1341 83 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 20093333 Nonpathogen - methyl coenzyme M reductase, subunit C MA4549 14 COG4055 McrD, Methyl coenzyme M reductase, subunit D Coenzyme metabolism 20090536 Common aspC aspartyl-tRNA synthetase MA1684 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 20090207 Common - drug-efflux transporter MA1346 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20092631 Nonpathogen - hypothetical protein MA3835 1 None None None 20089153 Common - 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF MA0255 225 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 20093303 Nonpathogen - hypothetical protein MA4518 3 COG4014 COG4014, Uncharacterized protein conserved in archaea Function unknown 20091014 Common - beta-1,4-galactosyltransferase MA2172 14 COG5017 COG5017, Uncharacterized conserved protein Function unknown 20090163 Common - type IV secretion system protein MA1299 139 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 20089295 Common - hypothetical protein MA0400 125 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 20092430 Nonpathogen murD UDP-N-acetylmuramoylalanine-D-glutamate ligase MA3630 15 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 20090256 Common - transcriptional regulator, CopG family MA1395 66 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 20091289 Common ppsA phosphoenolpyruvate synthase MA2458 161 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 20089360 Nonpathogen - hypothetical protein MA0471 2 None None None 20091214 Common - glycosyltransferase (group I) MA2383 82 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20090497 Nonpathogen - hypothetical protein MA1644 1 None None None 20093364 Nonpathogen - hypothetical protein MA4580 13 COG3364 COG3364, Zn-ribbon containing protein General function prediction only 20091204 Common - hypothetical protein MA2372 34 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 20090695 Nonpathogen - hypothetical protein MA1845 1 None None None 20092881 Nonpathogen crcB CrcB family protein MA4088 9 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 20090962 Common - hypothetical protein MA2119 46 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 20089121 Nonpathogen - hypothetical protein MA0223 4 None None None 20090650 Common - flavodoxin MA1799 68 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 20091774 Nonpathogen - hypothetical protein MA2955 1 None None None 20090600 Common cbiQ cobalt ABC transporter, permease protein MA1748 62 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20093291 Common - Na-K-Cl cotransporter MA4506 64 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 20093355 Nonpathogen mrpB putative monovalent cation/H+ antiporter subunit B MA4665 3 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 20093148 Common - hypothetical protein MA4361 9 COG1470 COG1470, Predicted membrane protein Function unknown 20090265 Common - hypothetical protein MA1405 7 COG0398 COG0398, Uncharacterized conserved protein Function unknown 20093155 Common - hydrogenase membrane subunit MA4368 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 20093032 Common - hypothetical protein MA4242 37 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 20089086 Common - hypothetical protein MA0188 113 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20090777 Nonpathogen - hypothetical protein MA1928 5 None None None 20092126 Common - hypothetical protein MA3311 13 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090494 Common - hypothetical protein MA1640 52 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 20093027 Common hdrB heterodisulfide reductase, subunit B MA4237 79 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 20092248 Common - hypothetical protein MA3436 168 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20089584 Common oppC oligopeptide ABC transporter, permease protein MA0699 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20090326 Nonpathogen - hypothetical protein MA1467 1 None None None 20090680 Nonpathogen - hypothetical protein MA1829 1 None None None 20092590 Common - integrase MA3794 172 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20092746 Nonpathogen - hypothetical protein MA3950 1 None None None 20090546 Nonpathogen - hypothetical protein MA1694 4 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 20090956 Common - hypothetical protein MA2113 13 None None None 20092829 Common - ABC transporter, ATP-binding protein MA4036 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20090429 Common - dienelactone hydrolase family protein MA1571 90 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 20089450 Common - hypothetical protein MA0561 7 None None None 20091756 Common - hypothetical protein MA2937 23 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091362 Nonpathogen - hypothetical protein MA2534 1 None None None 20092334 Common nadE NAD synthetase MA3526 235 COG0171 NadE, NAD synthase Coenzyme metabolism 20092857 Common - hypothetical protein MA4064 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 20093011 Nonpathogen - hypothetical protein MA4221 1 None None None 20090515 Nonpathogen - hypothetical protein MA1662 1 None None None 20092528 Common - cytidylyltransferase MA3731 47 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 20090761 Common dppC dipeptide ABC transporter, permease protein MA1912 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089233 Common - DNA helicase RepD MA0335 48 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 20088975 Common eif2B1 translation initiation factor IF-2B subunit alpha MA0076 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 20090506 Common - integral membrane protein MA1653 48 COG1836 COG1836, Predicted membrane protein Function unknown 20090253 Common - phosphoribosyl-ATP pyrophosphatase MA1392 159 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 20091102 Common - hypothetical protein MA2263 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20089748 Common - hypothetical protein MA0864 62 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 20091549 Nonpathogen - hypothetical protein MA2725 4 None None None 20091810 Common trpC indole-3-glycerol-phosphate synthase MA2992 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 20093436 Nonpathogen - hypothetical protein MA4657 1 None None None 20089486 Common rps9p 30S ribosomal protein S9P MA0597 246 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 20090878 Nonpathogen - hypothetical protein MA2030 3 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 20090634 Nonpathogen - hypothetical protein MA1783 23 COG1325 COG1325, Predicted exosome subunit Translation, ribosomal structure and biogenesis 20090862 Common - alanyl-tRNA synthetase domain protein MA2014 248 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 20092874 Common - hypothetical protein MA4081 80 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 20092849 Nonpathogen - hypothetical protein MA4056 1 None None None 20090184 Nonpathogen - hypothetical protein MA1323 1 None None None 20092067 Nonpathogen - hypothetical protein MA3251 1 None None None 20090321 Common - universal stress protein MA1462 156 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20089418 Common mttC trimethylamine corrinoid protein MA0529 168 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20091233 Nonpathogen - hypothetical protein MA2402 1 None None None 20093164 Common - sensory transduction histidine kinase MA4377 226 COG3322 COG3322, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 20090062 Common - hypothetical protein MA1196 21 COG5316 COG5316, Uncharacterized conserved protein Function unknown 20093223 Nonpathogen - hypothetical protein MA4437 7 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 20092211 Nonpathogen - hypothetical protein MA3399 4 None None None 161484939 Common groES co-chaperonin GroES MA0630 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 20090562 Common mch N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase MA1710 27 COG3252 COG3252, Methenyltetrahydromethanopterin cyclohydrolase Coenzyme metabolism 20091555 Nonpathogen - hypothetical protein MA2731 2 None None None 20090047 Nonpathogen - hypothetical protein MA1181 8 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 20090511 Nonpathogen - glutaredoxin MA1658 13 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 20089863 Nonpathogen - hypothetical protein MA0986 16 COG3369 COG3369, Uncharacterized conserved protein Function unknown 20090559 Nonpathogen - hypothetical protein MA1707 1 None None None 20092490 Common eif2G translation initiation factor IF-2 subunit gamma MA3690 249 COG5257 GCD11, Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) Translation, ribosomal structure and biogenesis 20092623 Nonpathogen - hypothetical protein MA3827 1 None None None 20093096 Nonpathogen - EF hand family protein MA4307 4 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089095 Nonpathogen - hypothetical protein MA0197 1 None None None 20091516 Common - transposase MA4675 45 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089071 Nonpathogen - hypothetical protein MA0173 16 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 20091690 Common - universal stress protein MA2866 145 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 20090106 Nonpathogen - hypothetical protein MA1242 1 None None None 20090938 Common - hypothetical protein MA2093 11 COG1695 COG1695, Predicted transcriptional regulators Transcription 20093409 Common - iron-sulfur binding reductase MA4630 174 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 20090231 Nonpathogen dph5 diphthine synthase MA1370 34 COG1798 DPH5, Diphthamide biosynthesis methyltransferase Translation, ribosomal structure and biogenesis 20093065 Nonpathogen rplP0 acidic ribosomal protein P0 MA4276 35 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 20093194 Common - hypothetical protein MA4407 188 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 20092469 Common - hypothetical protein MA3669 38 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 20090137 Common - ABC transporter, ATP-binding protein MA1273 235 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20090350 Common cofG FO synthase subunit 1 MA1491 69 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 20091622 Common - hypothetical protein MA2800 51 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092306 Nonpathogen - pyruvoyl-dependent arginine decarboxylase MA3496 26 COG1945 COG1945, Uncharacterized conserved protein Function unknown 20090450 Nonpathogen - hypothetical protein MA1592 1 None None None 20089992 Nonpathogen - hypothetical protein MA1126 6 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089480 Nonpathogen - hypothetical protein MA0591 15 COG3390 COG3390, Uncharacterized protein conserved in archaea Function unknown 20092658 Common cdhC acetyl-CoA decarbonylase/synthase complex subunit beta MA3862 19 COG1614 CdhC, CO dehydrogenase/acetyl-CoA synthase beta subunit Energy production and conversion 20091429 Nonpathogen - hypothetical protein MA2603 1 None None None 20090762 Common dppB dipeptide ABC transporter, permease protein MA1913 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091980 Common - hypothetical protein MA3162 17 COG5561 COG5561, Predicted metal-binding protein Function unknown 20092214 Common - hypothetical protein MA3402 23 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 20090015 Common - sensory transduction histidine kinase MA1149 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20089213 Nonpathogen - hypothetical protein MA0315 3 None None None 20092591 Nonpathogen - hypothetical protein MA3795 1 None None None 20093251 Nonpathogen - hypothetical protein MA4465 17 COG4743 COG4743, Predicted membrane protein Function unknown 20092141 Common istB IstB helper protein MA3327 105 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20092754 Nonpathogen - hypothetical protein MA3958 8 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20092483 Common - hypothetical protein MA3683 46 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20092004 Common - hypothetical protein MA3187 31 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 20091211 Nonpathogen - hypothetical protein MA2380 7 None None None 20090735 Nonpathogen - hypothetical protein MA1885 1 None None None 20091649 Nonpathogen - hypothetical protein MA2825 1 None None None 20093241 Nonpathogen - hypothetical protein MA4455 21 COG1817 COG1817, Uncharacterized protein conserved in archaea Function unknown 20091592 Common - transposase MA2770 47 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089681 Common - polysaccharide deacetylase MA0797 114 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20089028 Nonpathogen - hypothetical protein MA0129 13 COG4033 COG4033, Uncharacterized protein conserved in archaea Function unknown 20089652 Common - hypothetical protein MA0767 50 COG2361 COG2361, Uncharacterized conserved protein Function unknown 20090342 Common trkH sodium transport protein MA1483 151 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 20090656 Nonpathogen mtxA tetrahydromethanopterin S-methyltransferase subunit A MA1805 17 COG4063 MtrA, Tetrahydromethanopterin S-methyltransferase, subunit A Coenzyme metabolism 20089695 Common hit histidine triad protein MA0811 239 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 20091561 Common - transposase MA2738 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092553 Common - lipopolysaccharide transferase family protein MA3755 137 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20091837 Nonpathogen - replication factor A MA3019 17 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 20090245 Common - 6-phospho-3-hexuloisomerase MA1384 127 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 20093230 Nonpathogen - hypothetical protein MA4444 8 None None None 20092233 Nonpathogen - hypothetical protein MA3421 1 None None None 20090828 Common isf-11 iron-sulfur flavoprotein MA1980 51 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20093014 Common - hypothetical protein MA4224 20 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20090841 Common - hypothetical protein MA1993 19 None None None 20090969 Nonpathogen - hypothetical protein MA2126 1 None None None 20091460 Nonpathogen - hypothetical protein MA2637 1 None None None 20089057 Nonpathogen - hypothetical protein MA0159 9 None None None 20091093 Common - kinesin light chain MA2255 98 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 20093322 Nonpathogen - hypothetical protein MA4537 1 None None None 20089778 Common - hypothetical protein MA0894 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 20090525 Common eno phosphopyruvate hydratase MA1672 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 20089959 Nonpathogen rpl32e 50S ribosomal protein L32e MA1089 34 COG1717 RPL32, Ribosomal protein L32E Translation, ribosomal structure and biogenesis 20092241 Nonpathogen - hypothetical protein MA3429 12 COG1633 COG1633, Uncharacterized conserved protein Function unknown 20092864 Nonpathogen - hypothetical protein MA4071 3 None None None 20091270 Common atp-1 H(+)-transporting ATP synthase, gene 1 MA2439 21 None None None 20092603 Nonpathogen - hypothetical protein MA3807 1 None None None 20089490 Common - hypothetical protein MA0601 71 COG1355 COG1355, Predicted dioxygenase General function prediction only 20090896 Nonpathogen - hypothetical protein MA2049 1 None None None 20091885 Common cheB1 chemotaxis-specific methylesterase MA3067 214 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 20090409 Nonpathogen - hypothetical protein MA1551 14 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 20090438 Common - hypothetical protein MA1580 2 None None None 20090590 Common - cell surface protein MA1738 52 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20089607 Common - Sep-tRNA:Cys-tRNA synthetase MA0722 119 COG1103 COG1103, Archaea-specific pyridoxal phosphate-dependent enzymes General function prediction only 20092386 Common - ABC transporter, ATP-binding protein MA3582 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20089594 Common - hypothetical protein MA0709 60 COG0433 COG0433, Predicted ATPase General function prediction only 20089058 Common - hypothetical protein MA0160 45 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 20089956 Nonpathogen rps14P 30S ribosomal protein S14P MA1086 33 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 20092733 Common - hypothetical protein MA3937 94 COG0701 COG0701, Predicted permeases General function prediction only 20089025 Nonpathogen - hypothetical protein MA0126 13 COG4033 COG4033, Uncharacterized protein conserved in archaea Function unknown 20091772 Common - hypothetical protein MA2953 111 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 20091596 Common - O-methyltransferase MA2773 50 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 20091041 Common - MoxR-related protein MA2200 84 COG0714 COG0714, MoxR-like ATPases General function prediction only 20091116 Common - pirin MA2278 148 COG1741 COG1741, Pirin-related protein General function prediction only 20091601 Common - hypothetical protein MA2778 12 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20092336 Nonpathogen - hypothetical protein MA3528 16 COG1873 COG1873, Uncharacterized conserved protein Function unknown 20089197 Common oppD oligopeptide ABC transporter, ATP-binding protein MA0299 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20093318 Common - iron compounds ABC transporter, permease protein MA4533 193 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20093327 Common thyA thymidylate synthase MA4543 103 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 20091073 Common - hypothetical protein MA2233 8 None None None 20092715 Common - iron ABC transporter, ATP-binding protein MA3919 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20092133 Nonpathogen - hypothetical protein MA3319 1 None None None 20092744 Nonpathogen - hypothetical protein MA3948 1 None None None 20093042 Common oppD oligopeptide ABC transporter, ATP-binding protein MA4252 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20093237 Nonpathogen - hypothetical protein MA4451 1 None None None 20090975 Nonpathogen - hypothetical protein MA2132 2 None None None 20089562 Nonpathogen - hypothetical protein MA0677 2 None None None 20093037 Common dppA dipeptide ABC transporter, solute-binding protein MA4247 212 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20093262 Nonpathogen - hypothetical protein MA4477 2 None None None 20092416 Nonpathogen - hypothetical protein MA3616 1 None None None 20090385 Nonpathogen - 30S ribosomal protein S6e MA1526 34 COG2125 RPS6A, Ribosomal protein S6E (S10) Translation, ribosomal structure and biogenesis 20092515 Common - long-chain fatty-acid-CoA ligase MA3717 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20089424 Common lysM LysM protein MA0535 42 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20092640 Common - hypothetical protein MA3844 3 None None None 20092225 Nonpathogen - hypothetical protein MA3413 10 COG4818 COG4818, Predicted membrane protein Function unknown 20089718 Common fwdB formylmethanofuran dehydrogenase, subunit B MA0834 138 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 20091787 Common - hypothetical protein MA2969 48 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 20091056 Common - ABC transporter, ATP-binding protein MA2215 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20089884 Nonpathogen erf1 peptide chain release factor 1 MA1008 34 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 20090750 Nonpathogen - hypothetical protein MA1900 1 None None None 20089337 Common - hypothetical protein MA0446 18 COG3153 COG3153, Predicted acetyltransferase General function prediction only 20090757 Nonpathogen - hypothetical protein MA1908 1 None None None 20092207 Nonpathogen - hypothetical protein MA3395 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20091374 Common - hypothetical protein MA2547 2 None None None 20089790 Nonpathogen - hypothetical protein MA0912 2 None None None 20090664 Common - hypothetical protein MA1813 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 20091540 Common nadA quinolinate synthetase MA2716 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 20092894 Common proB gamma-glutamyl kinase MA4101 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 20091831 Common dys putative deoxyhypusine synthase MA3013 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 20089455 Nonpathogen - hypothetical protein MA0566 1 None None None 20092676 Common hppA membrane-bound proton-translocating pyrophosphatase MA3880 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 20092258 Common - hypothetical protein MA3446 92 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 20089722 Nonpathogen - hypothetical protein MA0838 2 None None None 20090224 Common - phosphoglycolate phosphatase MA1363 195 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 20091876 Nonpathogen - hypothetical protein MA3058 4 None None None 20090229 Common - thioredoxin reductase (NADPH) MA1368 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 20093091 Nonpathogen - hypothetical protein MA4302 6 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20091356 Common - cellulosomal protein MA2528 15 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 20091035 Common - hypothetical protein MA2194 6 None None None 20090992 Common fecD Fe(III) dicitrate ABC transporter, permease MA2149 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20092076 Common - O-GlcNAc transferase, p110 subunit MA3260 155 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 20092704 Common oppD oligopeptide ABC transporter, ATP-binding protein MA3908 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089063 Common - hypothetical protein MA0165 48 COG1944 COG1944, Uncharacterized conserved protein Function unknown 20090000 Common - carbonic anhydrase/acetyltransferase isoleucine patch superfamily protein MA1134 212 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 20089802 Common lrp leucine responsive regulatory protein MA0924 155 COG1522 Lrp, Transcriptional regulators Transcription 20092378 Nonpathogen - hypothetical protein MA3572 2 None None None 20093426 Common - hypothetical protein MA4647 165 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 20090620 Nonpathogen - hypothetical protein MA1769 2 None None None 20092232 Nonpathogen - hypothetical protein MA3420 1 None None None 20092871 Nonpathogen - hypothetical protein MA4078 14 COG5427 COG5427, Uncharacterized membrane protein Function unknown 20092813 Common - cobalt transport protein MA4019 54 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20092501 Nonpathogen - hypothetical protein MA3701 1 None None None 20090582 Common - cell surface protein MA1730 26 COG3291 COG3291, FOG: PKD repeat General function prediction only 20091573 Common - hypothetical protein MA2750 15 None None None 20088952 Nonpathogen - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MA0053 4 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 20092454 Common - acetyltransferase (GNAT) family protein MA3654 19 COG2153 ElaA, Predicted acyltransferase General function prediction only 20091257 Common - amino acid permease MA2426 151 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 20090577 Common - phenylacetate-CoA ligase MA1725 116 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 20088985 Common hsp60-1 Hsp60 MA0086 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 20093301 Nonpathogen - nonhistone chromosomal protein MC1 MA4516 8 None None None 20092926 Common istB IstB helper protein MA4133 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090859 Common - glyoxalase MA2011 17 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 20089945 Common rpl2p 50S ribosomal protein L2P MA1075 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 20090283 Common - hypothetical protein MA1423 69 COG0824 FcbC, Predicted thioesterase General function prediction only 20091632 Nonpathogen - hypothetical protein MA2808 1 None None None 20092410 Common - hypothetical protein MA3610 50 COG3832 COG3832, Uncharacterized conserved protein Function unknown 20091921 Common arsC arsenate reductase MA3103 134 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 20090079 Common nifI2 P-II family nitrogen regulatory protein MA1215 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20091679 Nonpathogen - hypothetical protein MA2855 1 None None None 20091581 Nonpathogen - hypothetical protein MA2758 1 None None None 20091107 Nonpathogen - hypothetical protein MA2269 1 None None None 20090819 Nonpathogen - hypothetical protein MA1971 2 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 20089221 Common modC molybdenum ABC transporter, ATP-binding protein MA0323 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 20091813 Nonpathogen - hypothetical protein MA2995 1 None None None 20092713 Common amtB ammonium transporter MA3917 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 20092661 Common cdhE acetyl-CoA decarbonylase/synthase complex subunit gamma MA3865 23 COG1456 CdhE, CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) Energy production and conversion 20091763 Nonpathogen - hypothetical protein MA2944 2 None None None 20089098 Common - hypothetical protein MA0200 57 COG1993 COG1993, Uncharacterized conserved protein Function unknown 20089168 Nonpathogen mtrG tetrahydromethanopterin S-methyltransferase subunit G MA0270 14 COG4064 MtrG, Tetrahydromethanopterin S-methyltransferase, subunit G Coenzyme metabolism 20091023 Common - hypothetical protein MA2181 12 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20089441 Common - sensory transduction histidine kinase MA0552 193 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089895 Common - hypothetical protein MA1020 98 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20093282 Nonpathogen - hypothetical protein MA4497 1 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 20091697 Common - hypothetical protein MA2875 75 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20091943 Nonpathogen - hypothetical protein MA3125 2 None None None 20093139 Common - GTP-binding protein MA4351 249 COG1163 DRG, Predicted GTPase General function prediction only 20090548 Nonpathogen - hypothetical protein MA1696 2 None None None 161484936 Nonpathogen mtxH tetrahydromethanopterin S-methyltransferase subunit H MA1804 17 COG1962 MtrH, Tetrahydromethanopterin S-methyltransferase, subunit H Coenzyme metabolism 20090703 Nonpathogen - hypothetical protein MA1853 19 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 20088995 Common - helicase MA0096 55 COG1111 MPH1, ERCC4-like helicases DNA replication, recombination, and repair 20089891 Common cdhA acetyl-CoA decarbonylase/synthase complex subunit alpha MA1016 19 COG1152 CdhA, CO dehydrogenase/acetyl-CoA synthase alpha subunit Energy production and conversion 20090789 Nonpathogen - hypothetical protein MA1940 1 None None None 20092131 Common atsB arylsulfatase regulator MA3317 113 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 20092931 Nonpathogen - hypothetical protein MA4138 1 None None None 20091796 Nonpathogen - hypothetical protein MA2978 1 None None None 20092010 Nonpathogen rpl37e 50S ribosomal protein L37e MA3194 29 COG2126 RPL37A, Ribosomal protein L37E Translation, ribosomal structure and biogenesis 20090523 Nonpathogen - hypothetical protein MA1670 10 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20091767 Common - transcriptional regulator, TetR family MA2948 76 COG1309 AcrR, Transcriptional regulator Transcription 20091866 Common oppA oligopeptide ABC transporter, solute-binding protein MA3048 216 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20092349 Common - conserved hypothetical chemotaxis protein MA3542 162 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 20092621 Nonpathogen - hypothetical protein MA3825 1 None None None 20093100 Nonpathogen - hypothetical protein MA4311 1 None None None 20091225 Nonpathogen - hypothetical protein MA2394 1 None None None 20090030 Common - chromosome segregation protein MA1164 212 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 20089855 Common frhB coenzyme F420-reducing hydrogenase subunit beta MA0978 36 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 20089989 Nonpathogen - hypothetical protein MA1123 1 None None None 20090476 Nonpathogen - hypothetical protein MA1619 1 None None None 20091381 Nonpathogen - hypothetical protein MA2554 1 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 20092177 Nonpathogen - hypothetical protein MA3363 1 None None None 20093144 Nonpathogen - hypothetical protein MA4357 2 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 20089448 Nonpathogen - hypothetical protein MA0559 2 None None None 20090067 Nonpathogen - hypothetical protein MA1202 1 None None None 20092049 Nonpathogen - hypothetical protein MA3233 1 None None None 20091385 Common - hypothetical protein MA2558 15 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 20091152 Nonpathogen - hypothetical protein MA2314 1 None None None 20091905 Nonpathogen - hypothetical protein MA3087 4 None None None 20092424 Nonpathogen endA tRNA splicing endonuclease MA3624 34 COG1676 SEN2, tRNA splicing endonuclease Translation, ribosomal structure and biogenesis 20093433 Common selB translation elongation factor MA4654 129 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 20089707 Common recJ ss-DNA-specific exonuclease MA0823 54 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 20089965 Common secY preprotein translocase subunit SecY MA1095 165 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 20091083 Common - hypothetical protein MA2243 61 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20089494 Common - metallo-beta-lactamase MA0605 161 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 20090480 Nonpathogen - hypothetical protein MA1625 1 None None None 20092100 Nonpathogen - hypothetical protein MA3285 16 COG3366 COG3366, Uncharacterized protein conserved in archaea Function unknown 20089460 Nonpathogen - hypothetical protein MA0571 1 None None None 20089984 Common - ABC transporter, permease protein MA1118 192 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 20088965 Nonpathogen - hypothetical protein MA0066 1 None None None 20090364 Common fpoM F(420)H(2) dehydrogenase, subunit FpoM MA1505 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 20090107 Common - hypothetical protein MA1243 14 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 20089239 Nonpathogen fibM fibrillarin MA0341 34 COG1889 NOP1, Fibrillarin-like rRNA methylase Translation, ribosomal structure and biogenesis 20089617 Nonpathogen - hypothetical protein MA0732 4 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 20092191 Common - hypothetical protein MA3377 25 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 20092832 Nonpathogen - hypothetical protein MA4039 10 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 20089436 Nonpathogen - hypothetical protein MA0547 33 COG1339 COG1339, Transcriptional regulator of a riboflavin/FAD biosynthetic operon Transcription / Coenzyme metabolism 20091319 Common - ABC transporter, ATP-binding protein MA2488 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20089038 Common secD preprotein translocase subunit SecD MA0139 28 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 20093166 Common mtaA methylcobalamin:coenzyme M methyltransferase MA4379 121 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20091186 Common ppx exopolyphosphatase MA2351 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 20089515 Common - antigen MA0627 34 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 20090988 Common proV glycine betaine/L-proline ABC transporter, ATP-binding protein MA2145 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 20091799 Nonpathogen - hypothetical protein MA2981 2 None None None 20090339 Common trkA potassium transporter peripheral membrane component MA1480 161 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 20090779 Nonpathogen - transposase MA1930 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091182 Nonpathogen - hypothetical protein MA2347 6 None None None 20089467 Common hemB delta-aminolevulinic acid dehydratase MA0578 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 20092155 Nonpathogen - hypothetical protein MA3341 1 None None None 20091975 Nonpathogen - hypothetical protein MA3157 1 None None None 20090637 Common - transposase MA1786 68 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091246 Common hsdS type I restriction modification enzyme protein S MA2415 97 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 20089806 Nonpathogen - hypothetical protein MA0928 2 None None None 20090714 Common - helicase MA1864 28 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 20091030 Nonpathogen - transposase MA2189 3 None None None 20091104 Common - sensory transduction histidine kinase MA2266 127 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092572 Common - hypothetical protein MA3776 31 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 20090595 Nonpathogen - hypothetical protein MA1743 9 COG4069 COG4069, Uncharacterized protein conserved in archaea Function unknown 20090936 Common - short chain dehydrogenase MA2091 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 20092160 Common - sensory transduction histidine kinase MA3346 169 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20092445 Common - reverse transcriptase MA3645 83 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20089010 Nonpathogen - hypothetical protein MA0111 1 None None None 20089570 Common - sulfite reductase MA0685 165 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 20091054 Nonpathogen - hypothetical protein MA2213 1 None None None 20091379 Nonpathogen - hypothetical protein MA2552 2 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 20092839 Common metG methionyl-tRNA synthetase MA4046 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20091887 Nonpathogen - hypothetical protein MA3069 13 COG2469 COG2469, Uncharacterized conserved protein Function unknown 20091478 Common - MuT/NUDIX protein MA2655 6 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 20092000 Common - squalene-hopene cyclase MA3182 15 COG1657 SqhC, Squalene cyclase Lipid metabolism 20092541 Common fprA flavoprotein A MA3743 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 20092920 Common ssr site-specific recombinase MA4127 170 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20092943 Common - polyprenyl synthetase MA4150 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 20090617 Common - cell surface protein MA1766 75 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092479 Common - hypothetical protein MA3679 6 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 20090812 Common - phosphoribosylformylglycinamidine synthase subunit PurS MA1964 93 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 20089369 Nonpathogen - hypothetical protein MA0480 1 None None None 20091926 Common - glutathione-regulated potassium-efflux system protein MA3108 220 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 20089272 Nonpathogen - hypothetical protein MA0375 3 None None None 20089990 Nonpathogen - hypothetical protein MA1124 1 None None None 20090303 Nonpathogen - hypothetical protein MA1444 22 COG1460 COG1460, Uncharacterized protein conserved in archaea Function unknown 20092198 Nonpathogen - hypothetical protein MA3384 1 None None None 20090923 Common - DNA-(apurinic or apyrimidinic site) lyase MA2077 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 20089286 Nonpathogen - hypothetical protein MA0389 1 None None None 20090832 Nonpathogen - hypothetical protein MA1984 1 None None None 20092069 Nonpathogen - hypothetical protein MA3253 16 COG2454 COG2454, Uncharacterized conserved protein Function unknown 20089017 Common hisC histidinol-phosphate aminotransferase MA0118 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 20089371 Nonpathogen - hypothetical protein MA0482 1 None None None 20089771 Common pstS phosphate ABC transporter, solute-binding protein MA0887 156 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 20089181 Common modA molybdenum-binding protein MA0283 108 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 20092907 Nonpathogen rpl39e 50S ribosomal protein L39e MA4114 12 COG2167 RPL39, Ribosomal protein L39E Translation, ribosomal structure and biogenesis 20089788 Nonpathogen - hypothetical protein MA0910 1 None None None 20093126 Common - iron dependent repressor MA4338 117 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 20091489 Common - aldolase MA2666 71 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 20090412 Common - hypothetical protein MA1554 18 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 20090850 Common - hypothetical protein MA2002 37 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 20091987 Common gdhA glutamate dehydrogenase (NAD(P)+) MA3169 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 20088905 Common - pyridoxal-dependent decarboxylase MA0006 128 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 20091427 Nonpathogen - hypothetical protein MA2601 4 None None None 20092110 Common - hypothetical protein MA3295 13 COG3478 COG3478, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 20092956 Common - hypothetical protein MA4163 156 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 20090132 Common - response regulator receiver MA1268 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 20089250 Common - hypothetical protein MA0352 92 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 20093347 Common hyuA hydantoinase MA4563 114 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20090607 Common - cell surface protein MA1756 48 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090901 Nonpathogen - hypothetical protein MA2054 1 None None None 20090807 Common rnhB ribonuclease HII MA1959 218 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 20092484 Nonpathogen - hypothetical protein MA3684 13 COG4749 COG4749, Uncharacterized protein conserved in archaea Function unknown 20093088 Common - cell surface protein MA4299 100 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090769 Common - hypothetical protein MA1920 34 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20093081 Common - cell surface protein MA4292 107 COG3291 COG3291, FOG: PKD repeat General function prediction only 20091295 Common - hypothetical protein MA2464 71 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 20090324 Nonpathogen - hypothetical protein MA1465 1 None None None 20089323 Nonpathogen - ferredoxin MA0431 9 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 20089554 Common - hypothetical protein MA0667 44 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 20093375 Common deoC fructose-bisphosphate aldolase MA4591 90 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 20091129 Common - aldo/keto reductase MA2291 191 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20092278 Common - ABC transporter, ATP-binding protein MA3465 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20091710 Common - histone deacetylase MA2888 161 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 20090041 Common - mannosyltransferase MA1175 180 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20089677 Nonpathogen - hypothetical protein MA0793 3 COG4301 COG4301, Uncharacterized conserved protein Function unknown 20092419 Nonpathogen - nonhistone chromosomal protein MC1 MA3619 8 None None None 20089266 Common - hypothetical protein MA0369 27 COG1641 COG1641, Uncharacterized conserved protein Function unknown 20090737 Nonpathogen - hypothetical protein MA1887 1 None None None 20090372 Common - hypothetical protein MA1513 17 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 20091197 Common - hypothetical protein MA2364 30 COG4930 COG4930, Predicted ATP-dependent Lon-type protease Posttranslational modification, protein turnover, chaperones 20089997 Common - iron ABC transporter, permease protein MA1131 193 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20090981 Nonpathogen - hypothetical protein MA2138 1 None None None 20089350 Nonpathogen - hypothetical protein MA0459 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 20090310 Nonpathogen - hypothetical protein MA1451 1 None None None 20089645 Common lysS lysyl-tRNA synthetase MA0760 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 20092093 Nonpathogen - hypothetical protein MA3278 1 None None None 20092986 Common nifB nitrogen fixation protein MA4195 128 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20091741 Common - transcriptional regulator, ArsR family MA2921 18 COG1777 COG1777, Predicted transcriptional regulators Transcription 20092442 Common - iron ABC transporter, ATP-binding protein MA3642 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 20091827 Common - carbon-nitrogen hydrolase MA3009 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 20092042 Nonpathogen - hypothetical protein MA3226 1 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 20093002 Nonpathogen - hypothetical protein MA4212 1 None None None 20090048 Common - hypothetical protein MA1182 29 COG0392 COG0392, Predicted integral membrane protein Function unknown 20090652 Common - hypothetical protein MA1801 130 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 20090182 Common - short chain dehydrogenase MA1321 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 20092612 Nonpathogen - hypothetical protein MA3816 1 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 20092060 Nonpathogen - hypothetical protein MA3244 1 None None None 20091437 Nonpathogen - hypothetical protein MA2611 1 None None None 20090080 Common vnfD nitrogenase, subunit alpha MA1216 52 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20090823 Nonpathogen - hypothetical protein MA1975 3 None None None 20092960 Nonpathogen - hypothetical protein MA4167 11 COG4742 COG4742, Predicted transcriptional regulator Transcription 20091287 Nonpathogen - hypothetical protein MA2456 1 None None None 20091739 Nonpathogen - hypothetical protein MA2919 1 None None None 20089123 Nonpathogen - hypothetical protein MA0225 2 None None None 20090376 Common - cell surface protein MA1517 42 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20092650 Common - acetolactate synthase, small subunit MA3854 38 COG4747 COG4747, ACT domain-containing protein General function prediction only 20092362 Common - hypothetical protein MA3555 116 COG1238 COG1238, Predicted membrane protein Function unknown 20093210 Common - hypothetical protein MA4424 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20092800 Common - cation efflux family protein MA4005 214 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 20092844 Common - hypothetical protein MA4051 6 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 20092369 Nonpathogen pfk ADP-specific phosphofructokinase MA3563 8 COG4809 COG4809, Archaeal ADP-dependent phosphofructokinase/glucokinase Carbohydrate transport and metabolism 20091963 Common - hypothetical protein MA3145 15 COG5426 COG5426, Uncharacterized membrane protein Function unknown 20091331 Common - hypothetical protein MA2500 145 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 20090143 Nonpathogen - hypothetical protein MA1279 31 COG1829 COG1829, Predicted archaeal kinase (sugar kinase superfamily) General function prediction only 20088918 Common mcp-2 methyl-accepting chemotaxis protein MA0019 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 20089757 Common - PQQ enzyme repeat domain protein MA0873 6 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20089675 Nonpathogen ubiA prenyltransferase MA0791 5 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 20090360 Common fpoJ NADH dehydrogenase subunit J MA1501 106 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 20090906 Nonpathogen - 4-carboxymuconolactone decarboxylase MA2059 2 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20091268 Common - F0F1 ATP synthase subunit A MA2437 198 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 20092470 Common - hypothetical protein MA3670 99 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 20092971 Common fmdB formylmethanofuran dehydrogenase, subunit B MA4178 139 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 20093207 Common - UbiA prenyltransferase MA4420 63 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 20091720 Common - hypothetical protein MA2899 11 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 20092271 Common nikB nickel ABC transporter, permease protein MA4673 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089848 Common fur ferric uptake regulation protein MA0971 184 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 20089687 Nonpathogen - hypothetical protein MA0803 9 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089547 Common nqr2 Na+-transporting NADH:ubiquinone oxidoreductase, subunit 2 MA0660 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 20089257 Common - outer membrane protein expression inhibitor MA0360 107 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 20089827 Nonpathogen rps15p 30S ribosomal protein S15P MA0949 34 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 20089408 Nonpathogen - hypothetical protein MA0519 18 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 20092725 Nonpathogen - hypothetical protein MA3929 2 None None None 20089394 Nonpathogen - hypothetical protein MA0505 4 None None None 20092055 Nonpathogen - hypothetical protein MA3239 1 None None None 20089178 Common - hypothetical protein MA0280 43 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 20090028 Common - hypothetical protein MA1162 28 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 20092027 Nonpathogen - hypothetical protein MA3211 3 None None None 20093277 Nonpathogen - hypothetical protein MA4492 2 None None None 20091665 Nonpathogen - hypothetical protein MA2841 3 None None None 20089284 Common - zinc transporter ZupT MA0387 106 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 20091465 Common - hypothetical protein MA2642 212 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 20091064 Common - transposase A MA2224 87 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20092698 Common modB molybdenum ABC transporter, permease protein MA3902 234 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 20090943 Common - hypothetical protein MA2099 36 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 20090913 Common - hypothetical protein MA2066 11 None None None 20090740 Nonpathogen - transposase MA1890 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20093423 Common - hypothetical protein MA4644 25 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 20093383 Common oppC oligopeptide ABC transporter, permease protein MA4599 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089831 Common - cell division protein FtsZ MA0953 81 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 20090151 Nonpathogen - hypothetical protein MA1287 1 None None None 20089307 Nonpathogen - hypothetical protein MA0414 3 COG1733 COG1733, Predicted transcriptional regulators Transcription 20092289 Common - hypothetical protein MA3478 16 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 20092949 Common atpC V-type ATP synthase subunit C MA4156 31 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 20089188 Nonpathogen - hypothetical protein MA0290 21 COG2023 RPR2, RNase P subunit RPR2 Translation, ribosomal structure and biogenesis 20091668 Nonpathogen - hypothetical protein MA2844 7 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 20089763 Common - oligopeptide ABC transporter, ATP-binding protein MA0879 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 20092668 Common - metal-dependent phosphohydrolase MA4682 27 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 20091209 Nonpathogen - hypothetical protein MA2377 1 None None None 20090417 Nonpathogen - hypothetical protein MA1559 1 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090444 Common - DNA topoisomerase VI subunit A MA1586 34 COG1697 COG1697, DNA topoisomerase VI, subunit A DNA replication, recombination, and repair 20093130 Common - membrane associated ATPase MA4342 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 20091308 Common - peptide ABC transporter, solute-binding protein MA2477 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20091459 Nonpathogen - hypothetical protein MA2636 1 COG4803 COG4803, Predicted membrane protein Function unknown 20089875 Common - hypothetical protein MA0999 15 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20093381 Common oppF oligopeptide ABC transporter, ATP-binding protein MA4597 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 20091480 Nonpathogen - hypothetical protein MA2657 2 None None None 20091402 Nonpathogen - hypothetical protein MA2576 1 None None None 20089103 Nonpathogen - hypothetical protein MA0205 8 COG4742 COG4742, Predicted transcriptional regulator Transcription 20091830 Nonpathogen - pyruvoyl-dependent arginine decarboxylase MA3012 31 COG1945 COG1945, Uncharacterized conserved protein Function unknown 20090770 Common - hypothetical protein MA1921 45 None None None 20091301 Common - hypothetical protein MA2470 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092968 Common fmdA formylmethanofuran dehydrogenase, subunit A MA4175 31 COG1229 FwdA, Formylmethanofuran dehydrogenase subunit A Energy production and conversion 20090095 Common - iron(III) ABC transporter, solute-binding protein MA1231 75 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20092287 Nonpathogen - hypothetical protein MA3476 2 None None None 20089811 Nonpathogen mtbB dimethylamine methyltransferase MA0933 1 None None None 20090319 Common - phage shock protein A MA1460 81 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 20092407 Common pta phosphate acetyltransferase MA3607 162 COG0280 Pta, Phosphotransacetylase Energy production and conversion 20092197 Common - hypothetical protein MA3383 106 COG0393 COG0393, Uncharacterized conserved protein Function unknown 20089114 Common mat S-adenosylmethionine synthetase MA0216 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 20089244 Common - protoporphyrin IX magnesium chelatase MA0346 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20089542 Nonpathogen - hypothetical protein MA0655 22 COG1624 COG1624, Uncharacterized conserved protein Function unknown 20089818 Common - hypothetical protein MA0940 21 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 20089348 Nonpathogen - hypothetical protein MA0457 1 None None None 20092606 Nonpathogen - hypothetical protein MA3810 1 None None None 20092682 Common proS prolyl-tRNA synthetase MA3886 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20092178 Nonpathogen - hypothetical protein MA3364 1 None None None 20089525 Common - hypothetical protein MA0638 6 None None None 20090884 Nonpathogen - hypothetical protein MA2036 1 None None None 20091858 Common - hypothetical protein MA3040 12 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 20089610 Common - hypothetical protein MA0725 14 COG4739 COG4739, Uncharacterized protein containing a ferredoxin domain Function unknown 20091000 Nonpathogen - hypothetical protein MA2157 1 None None None 20090797 Common - glutamate decarboxylase MA1949 77 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 20090963 Common - type I site-specific deoxyribonuclease MA2120 49 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 20089039 Common - replication factor C small subunit 2 MA0140 246 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 20091118 Common modA molybdenum ABC transporter, solute-binding protein MA2280 165 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 20090869 Common - hypothetical protein MA2021 61 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20088916 Nonpathogen dyhC dynein heavy chain MA0017 1 None None None 20092526 Common ppsA pyruvate water dikinase MA3729 44 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 20092432 Common cadA cadmium efflux ATPase MA3632 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 20090344 Common - ferredoxin MA1485 61 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 20092402 Nonpathogen - hypothetical protein MA3601 8 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 20090293 Common - hypothetical protein MA1433 25 COG2006 COG2006, Uncharacterized conserved protein Function unknown 20090013 Common vhtA F420-nonreducing hydrogenase MA1147 100 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 20091420 Nonpathogen - hypothetical protein MA2594 1 None None None 20093264 Nonpathogen - transcriptional regulator, ArsR family MA4479 14 COG4189 COG4189, Predicted transcriptional regulator Transcription 20089648 Nonpathogen - hypothetical protein MA0763 2 None None None 20091563 Common - hypothetical protein MA2740 21 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20089352 Common - hypothetical protein MA0461 13 COG4715 COG4715, Uncharacterized conserved protein Function unknown 20093335 Nonpathogen - hypothetical protein MA4551 15 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 20091177 Nonpathogen - hypothetical protein MA2342 1 None None None 20090614 Common - transcriptional regulator, CopG family MA1763 64 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 20089097 Nonpathogen - hypothetical protein MA0199 11 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 20090148 Common - hypothetical protein MA1284 2 None None None 20089641 Nonpathogen - hypothetical protein MA0756 1 None None None 20090258 Nonpathogen - hypothetical protein MA1397 9 COG4069 COG4069, Uncharacterized protein conserved in archaea Function unknown 20090113 Common oppA oligopeptide ABC transporter, oligopeptide-binding protein MA1249 216 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20092790 Nonpathogen - hypothetical protein MA3995 14 COG4050 COG4050, Uncharacterized protein conserved in archaea Function unknown 20091413 Nonpathogen - hypothetical protein MA2587 1 None None None 20092883 Nonpathogen - hypothetical protein MA4090 1 None None None 20091212 Common - mannose-6-phosphate isomerase, bifunctional enzyme MA2381 206 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20091170 Common - cell surface protein MA2335 46 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090492 Common - transposase MA1637 54 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090580 Common - STARP antigen MA1728 13 None None None 20090958 Common - hypothetical protein MA2115 2 None None None 20090391 Nonpathogen - hypothetical protein MA1532 6 None None None 20090684 Common - methyltransferase MA1834 17 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 20093025 Common - F420-dependent NADP reductase MA4235 39 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 20091951 Common - cell surface protein MA3133 48 COG3291 COG3291, FOG: PKD repeat General function prediction only 20093006 Common glnA glutamate-ammonia ligase MA4216 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 20091206 Common - hypothetical protein MA2374 18 None None None 20092835 Common - acetyl-CoA acetyltransferase MA4042 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 20091518 Common - hypothetical protein MA2694 107 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 20091138 Common oplAH 5-oxoprolinase (ATP-hydrolyzing) MA2300 118 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 20091754 Common - phosphate permease MA2935 175 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 20088924 Common znuB zinc ABC transporter, permease protein MA0025 190 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 20092438 Common - hypothetical protein MA3638 36 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 20092674 Nonpathogen - hypothetical protein MA3878 2 None None None 20090609 Nonpathogen - hypothetical protein MA1758 3 None None None 20090749 Nonpathogen - hypothetical protein MA1899 1 None None None 20090186 Common aarF ubiquinone biosynthesis protein MA1325 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 20090499 Common - sensory transduction histidine kinase MA1646 191 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090693 Common - glyoxalase MA4669 25 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 20092124 Common purD phosphoribosylamine-glycine ligase MA3309 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 20089084 Nonpathogen - hypothetical protein MA0186 7 None None None 20089459 Nonpathogen - hypothetical protein MA0570 1 None None None 20093049 Common cbiH precorrin-3B C17-methyltransferase MA4259 179 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 20090709 Nonpathogen - hypothetical protein MA1859 2 None None None 20089367 Nonpathogen - hypothetical protein MA0478 1 None None None 20088966 Nonpathogen - hypothetical protein MA0067 11 COG4800 COG4800, Predicted transcriptional regulator with an HTH domain Transcription 20090872 Common - 30S ribosomal protein S17 MA2024 40 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 20093110 Common gldA gliding motility protein MA4321 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20089412 Common mutS DNA mismatch repair protein MA0523 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 20091324 Common - transcriptional regulator, TetR family MA2493 11 COG1309 AcrR, Transcriptional regulator Transcription 20090674 Nonpathogen - hypothetical protein MA1823 1 None None None 20089139 Common - phosphomannomutase MA0241 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 20088948 Common - hypothetical protein MA0049 31 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 20089112 Nonpathogen - hypothetical protein MA0214 1 None None None 20091802 Nonpathogen - hypothetical protein MA2984 1 None None None 20090800 Nonpathogen - hypothetical protein MA1952 1 None None None 20090602 Nonpathogen - hypothetical protein MA1750 1 COG1572 COG1572, Uncharacterized conserved protein Function unknown 20089270 Nonpathogen - hypothetical protein MA0373 2 None None None 20091005 Common cmtM methylcobalamin:coenzyme M methyltransferase MA2163 15 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20089907 Common - serine O-acetyltransferase MA1032 13 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 20090491 Common - homospermidine synthase MA1636 26 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 20089929 Common - hypothetical protein MA1059 13 None None None 20089208 Nonpathogen - hypothetical protein MA0310 3 None None None 20093366 Nonpathogen - hypothetical protein MA4582 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 20089158 Nonpathogen - hypothetical protein MA0260 5 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20091407 Nonpathogen - hypothetical protein MA2581 1 None None None 20090720 Common pepF thimet oligopeptidase MA1870 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 20091161 Common - hypothetical protein MA2325 42 COG5361 COG5361, Uncharacterized conserved protein Function unknown 20091583 Common - hypothetical protein MA2760 33 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 20090848 Common treX glycogen debranching enzyme MA2000 167 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 20092918 Common - hypothetical protein MA4125 16 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20092276 Common - ABC transporter, permease protein MA3463 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20092399 Nonpathogen - hypothetical protein MA3598 3 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092551 Nonpathogen - transmembrane oligosaccharyl transferase MA3753 25 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 20092342 Common - hypothetical protein MA3535 33 COG2320 GrpB, Uncharacterized conserved protein Function unknown 20091392 Common - hypothetical protein MA2566 46 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092096 Common - hypothetical protein MA3281 13 COG2835 COG2835, Uncharacterized conserved protein Function unknown 20090403 Common - hypothetical protein MA1545 54 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20090571 Nonpathogen - hypothetical protein MA1719 13 COG2430 COG2430, Uncharacterized conserved protein Function unknown 20090727 Nonpathogen - hypothetical protein MA1877 1 None None None 20089191 Nonpathogen - hypothetical protein MA0293 5 None None None 20091897 Nonpathogen - hypothetical protein MA3079 8 None None None 20090213 Nonpathogen - hypothetical protein MA1352 1 None None None 20089004 Common moaA molybdenum cofactor biosynthesis protein A MA0105 203 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 20090053 Common dpm dolichyl-phosphate beta-D-mannosyltransferase MA1187 154 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 20092313 Nonpathogen - hypothetical protein MA3503 1 None None None 20089977 Common rps13p 30S ribosomal protein S13P MA1108 210 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 20090589 Nonpathogen - hypothetical protein MA1737 1 None None None 20091607 Common - sensory transduction histidine kinase MA2784 194 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20091430 Nonpathogen - hypothetical protein MA2604 1 None None None 20091933 Nonpathogen - hypothetical protein MA3115 1 None None None 20093235 Nonpathogen - hypothetical protein MA4449 5 COG4906 COG4906, Predicted membrane protein Function unknown 20092850 Nonpathogen - transposase MA4057 3 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092186 Nonpathogen - hypothetical protein MA3372 7 COG1433 COG1433, Uncharacterized conserved protein Function unknown 20089044 Common mtbA methylcobalamin:coenzyme M methyltransferase MA0146 137 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 20091854 Nonpathogen - hypothetical protein MA3036 1 None None None 20093320 Common - hypothetical protein MA4535 62 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090504 Nonpathogen - methionine-10+ related protein MA1651 35 COG2520 COG2520, Predicted methyltransferase General function prediction only 20092766 Common purB adenylosuccinate lyase MA3971 236 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 20093117 Common - thiamine biosynthesis protein ThiC MA4329 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 20091918 Nonpathogen - hypothetical protein MA3100 2 None None None 20092787 Nonpathogen - hypothetical protein MA3992 14 COG4052 COG4052, Uncharacterized protein related to methyl coenzyme M reductase subunit C General function prediction only 20092311 Common - hypothetical protein MA3501 147 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 20091938 Common - surface antigen gene MA3120 103 COG3391 COG3391, Uncharacterized conserved protein Function unknown 20089603 Nonpathogen - putative diphthamide synthesis protein MA0718 34 COG1736 DPH2, Diphthamide synthase subunit DPH2 Translation, ribosomal structure and biogenesis 20090587 Common - malate dehydrogenase (oxaloacetate decarboxylating) MA1735 202 COG0281 SfcA, Malic enzyme Energy production and conversion 20090668 Nonpathogen ribC riboflavin synthase MA1817 22 COG1731 COG1731, Archaeal riboflavin synthase Coenzyme metabolism 20089970 Common - transcriptional regulator MA1101 10 COG0789 SoxR, Predicted transcriptional regulators Transcription 20091158 Nonpathogen - hypothetical protein MA2322 3 None None None 20091273 Common - hypothetical protein MA2442 25 COG4803 COG4803, Predicted membrane protein Function unknown 20090487 Common vnfN nitrogenase associated protein N MA1632 57 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 20092083 Common - hypothetical protein MA3267 13 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 20092692 Common nifI1 P-II family nitrogen regulatory protein MA3896 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 20092394 Common udg uracil-DNA glycosylase MA3593 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 20092320 Common - hypothetical protein MA3512 44 COG1478 COG1478, Uncharacterized conserved protein Function unknown 20090945 Nonpathogen - hypothetical protein MA2101 1 None None None 20092638 Common - cell surface protein MA3842 75 COG3291 COG3291, FOG: PKD repeat General function prediction only 20091262 Common ileS isoleucyl-tRNA synthetase MA2431 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20089922 Common - transposase MA1051 65 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091965 Common - hypothetical protein MA3147 119 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 20090191 Nonpathogen - hypothetical protein MA1330 4 COG3350 COG3350, Uncharacterized conserved protein Function unknown 20091111 Nonpathogen - hypothetical protein MA2273 10 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 20093058 Nonpathogen - hypothetical protein MA4269 34 COG1628 COG1628, Uncharacterized conserved protein Function unknown 20090821 Nonpathogen - integral membrane protein MA1973 21 COG1784 COG1784, Predicted membrane protein Function unknown 20091069 Nonpathogen - hypothetical protein MA2229 1 None None None 20089574 Common - hypothetical protein MA0689 30 COG1852 COG1852, Uncharacterized conserved protein Function unknown 20089726 Common oppB oligopeptide ABC transporter, permease MA0842 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091122 Common - cell surface protein MA2284 25 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090204 Nonpathogen - hypothetical protein MA1343 1 None None None 20092456 Nonpathogen - hypothetical protein MA3656 1 None None None 20089936 Common - hypothetical protein MA1066 6 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20089940 Nonpathogen - hypothetical protein MA1070 2 COG5652 COG5652, Predicted integral membrane protein Function unknown 20092702 Common oppB oligopeptide ABC transporter, permease protein MA3906 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091043 Common - transposase MA2202 90 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091360 Common mgl methionine gamma-lyase MA2532 214 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 20089795 Common - hypothetical protein MA0917 23 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 20089954 Nonpathogen - 30S ribosomal protein S4e MA1084 34 COG1471 RPS4A, Ribosomal protein S4E Translation, ribosomal structure and biogenesis 20093284 Nonpathogen - hypothetical protein MA4499 2 None None None 20091071 Common ssrA site-specific recombinase MA2231 172 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20092990 Common exsB succinoglycan biosynthesis regulator MA4199 153 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 20090431 Nonpathogen - hypothetical protein MA1573 1 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 20093044 Common - thioredoxin MA4254 222 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 20091521 Nonpathogen - hypothetical protein MA2697 1 None None None 20089151 Common - hypothetical protein MA0253 32 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 20092243 Nonpathogen - hypothetical protein MA3431 5 None None None 20089132 Common tadA1 type IV secretion system protein MA0234 222 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 20092717 Common hemU hemin ABC transporter, permease protein MA3921 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20092086 Common - hypothetical protein MA3270 4 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 20093428 Common - hypothetical protein MA4649 135 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 20089426 Nonpathogen - c-Myc-responsive protein MA0537 4 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 20089609 Nonpathogen - hypothetical protein MA0724 3 None None None 20090623 Common isf-7 iron-sulfur flavoprotein MA1773 35 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20089105 Nonpathogen - hypothetical protein MA0207 12 COG4189 COG4189, Predicted transcriptional regulator Transcription 20089432 Common pcm-2 protein-L-isoaspartate (D-aspartate) O-methyltransferase MA0543 165 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 20089905 Common nadE NAD synthetase MA1030 213 COG0171 NadE, NAD synthase Coenzyme metabolism 20092569 Nonpathogen - hypothetical protein MA3773 1 None None None 20090977 Common - hypothetical protein MA2134 9 COG1598 COG1598, Uncharacterized conserved protein Function unknown 20092514 Common - hypothetical protein MA3716 28 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 20089064 Common - copper P-type ATPase MA0166 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 20092239 Common - hypothetical protein MA3427 4 None None None 20090383 Common ndk nucleoside-diphosphate kinase MA1524 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 20092974 Common - polysaccharide deacetylase MA4181 58 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20089545 Common - hypothetical protein MA0658 9 None None None 20091531 Common - cell surface protein MA2707 15 COG3291 COG3291, FOG: PKD repeat General function prediction only 20092338 Common - hypothetical protein MA3531 15 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 20090994 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase MA2151 226 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089318 Nonpathogen - hypothetical protein MA0426 1 None None None 20089586 Common oppA oligopeptide ABC transporter, solute-binding protein MA0701 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20089445 Common - hypothetical protein MA0556 7 None None None 20091130 Common - aldo/keto reductase MA2292 183 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 20088961 Nonpathogen - hypothetical protein MA0062 6 None None None 20090238 Common - chorismate mutase MA1377 24 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 20090356 Common fpoC NADH dehydrogenase subunit C MA1497 181 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 20092680 Nonpathogen - hypothetical protein MA3884 14 COG2450 COG2450, Uncharacterized conserved protein Function unknown 20093228 Nonpathogen - hypothetical protein MA4442 5 None None None 20089335 Common isf-5 iron-sulfur flavoprotein MA0444 54 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20092818 Nonpathogen - hypothetical protein MA4024 1 None None None 20089834 Common ptpS 6-pyruvoyltetrahydropterin synthase MA0956 131 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 20092492 Common rpoE1 DNA-directed RNA polymerase subunit E' MA3692 45 COG1095 RPB7, DNA-directed RNA polymerase, subunit E' Transcription 20091970 Common cmd carboxymuconolactone decarboxylase MA3152 56 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20093279 Nonpathogen - hypothetical protein MA4494 2 None None None 20089439 Common aroC chorismate synthase MA0550 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 20091924 Nonpathogen - hypothetical protein MA3106 1 None None None 20091776 Nonpathogen - hypothetical protein MA2957 1 None None None 20092359 Common cbiQ cobalt ABC transporter, permease protein MA3552 51 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 20091862 Common - hypothetical protein MA3044 30 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 20089225 Common isf-1 iron-sulfur flavoprotein MA0327 45 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20089457 Nonpathogen - hypothetical protein MA0568 1 None None None 20091785 Common - haloacid dehalogenase-like hydrolase MA2967 178 COG0546 Gph, Predicted phosphatases General function prediction only 20090227 Common - response regulator receiver MA1366 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 20092205 Nonpathogen - hypothetical protein MA3392 1 None None None 20089596 Common - phenylacrylic acid decarboxylase MA0711 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 20091878 Nonpathogen - hypothetical protein MA3060 6 None None None 20092727 Nonpathogen - hypothetical protein MA3931 3 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20093186 Common cdhA acetyl-CoA decarbonylase/synthase complex subunit alpha MA4399 21 COG1152 CdhA, CO dehydrogenase/acetyl-CoA synthase alpha subunit Energy production and conversion 20088901 Nonpathogen - hypothetical protein MA0002 1 None None None 20090657 Nonpathogen mtxX methyltransferase MA1806 14 COG4002 COG4002, Predicted phosphotransacetylase General function prediction only 20093039 Common - hypothetical protein MA4249 141 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 20092006 Common - multidrug resistance operon repressor MA3189 49 COG1846 MarR, Transcriptional regulators Transcription 20089943 Common rpl4lp 50S ribosomal protein L4P MA1073 36 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 20092045 Common - cell surface protein MA3229 59 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089218 Common - acetyltransferase (GNAT) family protein MA0320 15 COG0456 RimI, Acetyltransferases General function prediction only 20089145 Common - hypothetical protein MA0247 55 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 20091989 Common - ABC transporter, ATP-binding protein MA3171 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20089235 Nonpathogen - hypothetical protein MA0337 2 COG3874 COG3874, Uncharacterized conserved protein Function unknown 20089484 Nonpathogen - 50S ribosomal protein L18e MA0595 34 COG1727 RPL18A, Ribosomal protein L18E Translation, ribosomal structure and biogenesis 20093190 Nonpathogen - hypothetical protein MA4403 3 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 20090045 Common - glycosyltransferase MA1179 160 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20089051 Nonpathogen - hypothetical protein MA0153 7 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 20090335 Nonpathogen - hypothetical protein MA1476 3 None None None 20093221 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase MA4435 99 COG1411 COG1411, Uncharacterized protein related to proFAR isomerase (HisA) General function prediction only 20090544 Common - phage integrase MA1692 163 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 20091512 Common - multidrug ABC transporter, ATP-binding protein MA2689 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20091823 Common - hypothetical protein MA3005 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091537 Nonpathogen - hypothetical protein MA2713 1 None None None 20093192 Common - metallo-beta-lactamase superfamily protein MA4405 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 20090141 Common - hypothetical protein MA1277 70 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 20091630 Common - hypothetical protein MA2807 47 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 20089073 Common - moaA/nifB/pqqE family protein MA0175 88 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20092820 Common - sensory transduction histidine kinase MA4026 152 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20090939 Nonpathogen - hypothetical protein MA2094 1 None None None 20090517 Nonpathogen - hypothetical protein MA1664 11 COG3355 COG3355, Predicted transcriptional regulator Transcription 20092291 Nonpathogen - hypothetical protein MA3480 1 None None None 20092997 Common - antibiotic resistance ABC transporter ATP-binding protein MA4206 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 20090179 Common ansA glutamyl-tRNA(Gln) amidotransferase subunit D MA1317 135 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 20090513 Common - hypothetical protein MA1660 38 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 20089581 Common - flavoprotein MA0696 31 COG1036 COG1036, Archaeal flavoproteins Energy production and conversion 20088990 Nonpathogen - translin family protein MA0091 24 COG2178 COG2178, Predicted RNA-binding protein of the translin family Translation, ribosomal structure and biogenesis 20092499 Common - cell surface protein MA3699 114 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090466 Common - hypothetical protein MA1608 23 COG4828 COG4828, Predicted membrane protein Function unknown 20090172 Common cooS carbon-monoxide dehydrogenase, catalytic subunit MA1309 26 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 20093063 Common rpl11p 50S ribosomal protein L11P MA4274 245 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 20089713 Nonpathogen - hypothetical protein MA0829 3 None None None 20091840 Common rfbA glucose-1-phosphate thymidylyltransferase MA3022 242 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 20089734 Common - cell surface protein MA0850 125 COG3291 COG3291, FOG: PKD repeat General function prediction only 20090984 Nonpathogen - hypothetical protein MA2141 1 None None None 20090932 Nonpathogen - hypothetical protein MA2087 4 None None None 20093083 Common - outer membrane protein MA4294 94 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20090733 Common istB IstB helper protein MA1883 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20092224 Nonpathogen - hypothetical protein MA3412 1 None None None 20091528 Nonpathogen - hypothetical protein MA2704 1 None None None 20092447 Common - hypothetical protein MA3647 60 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 20091658 Common - hypothetical protein MA2834 37 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 20093016 Nonpathogen - hypothetical protein MA4226 2 None None None 20090104 Nonpathogen - hypothetical protein MA1240 1 None None None 20089539 Nonpathogen pelA cell division protein pelota MA0652 34 COG1537 PelA, Predicted RNA-binding proteins General function prediction only 20091958 Common rfbM mannose-1-phosphate guanylyltransferase (GDP) MA3140 238 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 20093122 Common smc1 chromosome segregation protein MA4334 197 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 20091088 Common - hypothetical protein MA2249 19 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 20091692 Common hdrA heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta MA2868 68 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 20091230 Common - hypothetical protein MA2399 83 COG0778 NfnB, Nitroreductase Energy production and conversion 20092331 Nonpathogen - hypothetical protein MA3523 1 None None None 20089693 Common - hypothetical protein MA0809 47 COG2210 COG2210, Uncharacterized conserved protein Function unknown 20092593 Nonpathogen - hypothetical protein MA3797 1 None None None 20093243 Common - UDP-glucose 6-dehydrogenase MA4457 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 20091835 Nonpathogen - hypothetical protein MA3017 3 None None None 20093020 Nonpathogen - hypothetical protein MA4230 1 None None None 20091553 Common - transposase MA2729 108 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092251 Common - sulfite reductase, beta subunit MA3439 170 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 20091502 Common - reverse transcriptase MA2681 85 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 20090860 Common - response regulator receiver MA2012 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 20092731 Common - hypothetical protein MA3935 57 COG1993 COG1993, Uncharacterized conserved protein Function unknown 20091706 Common - hypothetical protein MA2884 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20089230 Common isf-2 iron-sulfur flavoprotein MA0332 41 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20092163 Nonpathogen - hypothetical protein MA3349 1 None None None 20093102 Nonpathogen - hypothetical protein MA4313 1 None None None 20089569 Common fprB hypothetical protein MA0684 20 COG1592 COG1592, Rubrerythrin Energy production and conversion 20089724 Common dppA dipeptide ABC transporter, solute-binding protein MA0840 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20092759 Common - ABC transporter, permease protein MA3963 170 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 20092613 Nonpathogen - hypothetical protein MA3817 1 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 20092062 Nonpathogen - hypothetical protein MA3246 1 None None None 20091113 Common - ABC transporter, ATP-binding protein MA2275 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20088903 Common istB IstB helper protein MA0004 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20089469 Nonpathogen - hypothetical protein MA0580 1 None None None 20091052 Common - transcription repressor MA2211 86 COG1846 MarR, Transcriptional regulators Transcription 20091510 Nonpathogen - hypothetical protein MA4680 2 None None None 20092019 Common - ski2-like helicase MA3203 150 COG1204 COG1204, Superfamily II helicase General function prediction only 20091317 Common - peptide ABC transporter, solute-binding protein MA2486 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 20090009 Nonpathogen vhtC cytochrome b MA1143 2 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 20091715 Common - hypothetical protein MA2894 61 COG5270 COG5270, PUA domain (predicted RNA-binding domain) Translation, ribosomal structure and biogenesis 20091132 Common - sensory transduction histidine kinase MA2294 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 20092193 Common - amino acid transporter MA3379 193 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 20092652 Nonpathogen - hypothetical protein MA3856 13 COG4020 COG4020, Uncharacterized protein conserved in archaea Function unknown 20089373 Nonpathogen - hypothetical protein MA0484 5 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20088930 Common porB pyruvate synthase, subunit beta MA0031 123 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 20092799 Nonpathogen - flap endonuclease-1 MA4004 34 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 20093174 Nonpathogen - hypothetical protein MA4387 1 COG4951 COG4951, Uncharacterized protein conserved in bacteria Function unknown 20091977 Nonpathogen - type I restriction modification system protein MA3159 1 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 20092091 Nonpathogen - hypothetical protein MA3276 1 None None None 20091188 Common - hypothetical protein MA2354 107 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 20089634 Common cysS cysteinyl-tRNA synthetase MA0749 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20089215 Common - hypothetical protein MA0317 32 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 20089841 Nonpathogen - hypothetical protein MA0963 19 COG1458 COG1458, Predicted DNA-binding protein containing PIN domain General function prediction only 20090110 Common oppC oligopeptide ABC transporter, permease MA1246 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091463 Nonpathogen - hypothetical protein MA2640 2 COG4803 COG4803, Predicted membrane protein Function unknown 20091377 Common - ABC transporter, permease protein MA2550 187 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 20092098 Common cooF carbon-monoxide dehydrogenase, Fe-S subunit MA3283 143 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 20093146 Common - hypothetical protein MA4359 24 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 20092574 Common rfbD dTDP-4-dehydrorhamnose reductase MA3778 170 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 20093398 Common - metallo-beta-lactamase MA4617 202 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 20091184 Common - phosphate-binding protein MA2349 27 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 20089438 Common - cation efflux system protein (zinc/cadmium) MA0549 214 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 20089689 Common czcD cation efflux system protein MA0805 212 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 20091647 Common - hypothetical protein MA2823 39 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 20092927 Nonpathogen - hypothetical protein MA4134 1 None None None 20092947 Common atpC H(+)-transporting ATP synthase, subunit C MA4154 29 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 20090699 Nonpathogen - hypothetical protein MA1849 2 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 20091617 Common - hypothetical protein MA2794 13 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 20092016 Nonpathogen - hypothetical protein MA3200 3 None None None 20093253 Nonpathogen - hypothetical protein MA4467 1 None None None 20090475 Common mtaC3 methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 3 MA1617 164 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 20091663 Common - ABC transporter, permease protein MA2839 21 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 20093316 Nonpathogen - hypothetical protein MA4531 3 None None None 20093157 Common - hypothetical protein MA4370 15 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 20089623 Nonpathogen - hypothetical protein MA0738 1 None None None 20089700 Nonpathogen - hypothetical protein MA0816 13 COG4021 COG4021, Uncharacterized conserved protein Function unknown 20091244 Common recG ATP-dependent DNA helicase MA2413 69 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 20090300 Common ksgA dimethyladenosine transferase MA1441 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 20090925 Common istB IstB helper protein MA2079 105 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20090531 Common - hypothetical protein MA1679 9 COG2940 COG2940, Proteins containing SET domain General function prediction only 20089711 Nonpathogen - hypothetical protein MA0827 4 None None None 20090374 Common - hypothetical protein MA1515 34 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 20089781 Nonpathogen nac nascent polypeptide-associated complex protein MA0902 33 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 20089019 Nonpathogen - hypothetical protein MA0120 10 COG4801 COG4801, Predicted acyltransferase General function prediction only 20090630 Common psmA proteasome subunit alpha MA1779 40 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 20093061 Nonpathogen secE preprotein translocase subunit SecE MA4272 2 COG2443 Sss1, Preprotein translocase subunit Sss1 Intracellular trafficking and secretion 20090414 Common - hypothetical protein MA1556 18 COG4983 COG4983, Uncharacterized conserved protein Function unknown 20090388 Nonpathogen - hypothetical protein MA1529 13 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 20093098 Common - cell surface protein MA4309 96 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089042 Nonpathogen mtmB1 monomethylamine methyltransferase MA0144 2 None None None 20092773 Common - lysine 2,3-aminomutase MA3979 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 20092588 Common - acetolactate synthase 3 catalytic subunit MA3792 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 20092938 Nonpathogen - endonuclease III MA4145 33 COG1833 COG1833, Uncharacterized conserved protein Function unknown 20090209 Common ebrA multidrug efflux pump MA1348 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 20091260 Nonpathogen - hypothetical protein MA2429 2 None None None 20092047 Nonpathogen - hypothetical protein MA3231 1 None None None 20090341 Common trkA potassium transporter peripheral membrane component MA1482 163 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 20090453 Nonpathogen - hypothetical protein MA1595 1 None None None 20089750 Common - hypothetical protein MA0866 51 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 20089590 Common - aldehyde dehydrogenase MA0705 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 20092107 Common - hypothetical protein MA3292 7 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 20090446 Nonpathogen - hypothetical protein MA1588 14 COG1522 Lrp, Transcriptional regulators Transcription 20088950 Common - hypothetical protein MA0051 24 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 20092916 Common pan proteasome-activating nucleotidase MA4123 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 20089963 Nonpathogen rpl30p 50S ribosomal protein L30P MA1093 34 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 20091673 Nonpathogen - hypothetical protein MA2849 1 None None None 20089471 Common hemC porphobilinogen deaminase MA0582 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 20092434 Nonpathogen - hypothetical protein MA3634 1 None None None 20090538 Common cpdA 3',5'-cyclic-nucleotide phosphodiesterase MA1686 64 COG1409 Icc, Predicted phosphohydrolases General function prediction only 20092230 Common - hypothetical protein MA3418 40 None None None 20091487 Common - LemA protein MA2664 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 20091201 Common recG ATP-dependent DNA helicase MA2369 78 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 20092802 Common yibO phosphoglyceromutase MA4007 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 20093349 Nonpathogen - hypothetical protein MA4565 1 None None None 20092138 Common uvrC excinuclease ABC subunit C MA3324 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 20090222 Common rimK ribosomal protein S6 modification protein MA1361 161 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 20088954 Nonpathogen - hypothetical protein MA0055 7 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 20090281 Nonpathogen - hypothetical protein MA1421 2 None None None 20091790 Nonpathogen mtmB2 monomethylamine methyltransferase MA2972 2 None None None 20088993 Nonpathogen - hypothetical protein MA0094 1 None None None 20089995 Nonpathogen - hypothetical protein MA1129 5 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 20090121 Common ef2 elongation factor EF-2 MA1257 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 20091699 Nonpathogen fwdG tungsten formylmethanofuran dehydrogenase, subunit G MA2877 13 COG1456 CdhE, CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) Energy production and conversion 20090687 Nonpathogen - hypothetical protein MA1837 1 None None None 20089246 Common - protoporphyrin IX magnesium chelatase MA0348 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 20090575 Common - hypothetical protein MA1723 83 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 20091081 Nonpathogen - hypothetical protein MA2241 4 None None None 20090882 Common - potassium channel protein MA2034 105 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 20090006 Common hypC hydrogenase expression/formation protein MA1140 42 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 20090077 Common nifH nitrogenase reductase MA1213 71 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 20091833 Common - hypothetical protein MA3015 23 COG1497 COG1497, Predicted transcriptional regulator Transcription 20092412 Common - hypothetical protein MA3612 69 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 20090557 Nonpathogen - hypothetical protein MA1705 1 None None None 20089934 Nonpathogen - hypothetical protein MA1064 12 COG1817 COG1817, Uncharacterized protein conserved in archaea Function unknown 20090309 Common - hypothetical protein MA1450 59 COG3174 COG3174, Predicted membrane protein Function unknown 20090489 Common - hypothetical protein MA1634 92 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20093188 Common - translation-associated GTPase MA4401 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 20090880 Common - nitrogen fixation protein NifH/NifE MA2032 71 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 20093270 Nonpathogen - hypothetical protein MA4485 4 None None None 20092901 Common - hypothetical protein MA4108 16 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20091948 Nonpathogen - hypothetical protein MA3130 10 COG4738 COG4738, Predicted transcriptional regulator Transcription 20089986 Common - ABC transporter, ATP-binding protein MA1120 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20089893 Common gap glyceraldehyde-3-phosphate dehydrogenase MA1018 48 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 20090712 Common lonA endopeptidase La MA1862 213 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 20092774 Nonpathogen - hypothetical protein MA3980 1 None None None 20090521 Common lolD lipoprotein releasing system, ATP-binding protein MA1668 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 20090280 Nonpathogen - cell surface protein MA1420 7 COG3291 COG3291, FOG: PKD repeat General function prediction only 20089492 Common - amino acid kinase MA0603 53 COG1608 COG1608, Predicted archaeal kinase General function prediction only 20092720 Nonpathogen - hypothetical protein MA3924 16 COG4871 COG4871, Uncharacterized protein conserved in archaea Function unknown 20091383 Nonpathogen - hypothetical protein MA2556 2 None None None 20092040 Nonpathogen - hypothetical protein MA3224 1 None None None 20092175 Common - transposase MA3361 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 20089170 Nonpathogen mtrA tetrahydromethanopterin S-methyltransferase subunit A MA0272 17 COG4063 MtrA, Tetrahydromethanopterin S-methyltransferase, subunit A Coenzyme metabolism 20091387 Common - hypothetical protein MA2560 18 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 20090165 Nonpathogen - hypothetical protein MA1301 1 None None None 20089166 Nonpathogen - hypothetical protein MA0268 1 None None None 20091015 Common pigA phosphatidylinositol glycan-class A MA2173 232 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 20091765 Common - hypothetical protein MA2946 13 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 20090247 Nonpathogen - hypothetical protein MA1386 1 None None None 20090817 Common - serine-type D-Ala-D-Ala carboxypeptidase MA1969 97 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 20090362 Common fpoK F(420)H(2) dehydrogenase, subunit FpoK MA1503 147 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 20091109 Common - hypothetical protein MA2271 20 None None None 20092153 Nonpathogen - hypothetical protein MA3339 1 None None None 20090676 Common - hypothetical protein MA1825 23 COG2013 COG2013, Uncharacterized conserved protein Function unknown 20090317 Nonpathogen - hypothetical protein MA1458 13 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 20093150 Common - cell surface protein MA4363 55 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 20089507 Common - sensory transduction histidine kinase MA0619 126 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 20089691 Common - NifU family protein MA0807 155 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 20090898 Common - transcriptional regulator, MarR family MA2051 133 COG1846 MarR, Transcriptional regulators Transcription 20089918 Common - hypothetical protein MA1046 14 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 20089658 Nonpathogen - hypothetical protein MA0774 1 None None None 20092181 Common - acylphosphatase MA3367 84 COG1254 AcyP, Acylphosphatases Energy production and conversion 20090904 Common - hypothetical protein MA2057 35 COG1378 COG1378, Predicted transcriptional regulators Transcription 20091783 Common - transposase MA2965 22 COG5421 COG5421, Transposase DNA replication, recombination, and repair 20091811 Common - hypothetical protein MA2993 142 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 20090802 Common - hypothetical protein MA1954 14 COG4923 COG4923, Uncharacterized conserved protein Function unknown 20090995 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase MA2152 223 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20090436 Common istB IstB helper protein MA1578 104 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 20089499 Nonpathogen tfb transcription initiation factor IIB MA0610 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 20093124 Nonpathogen - hypothetical protein MA4336 1 None None None 20093205 Nonpathogen - nucleotidyltransferase MA4418 8 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 20092642 Common - hypothetical protein MA3846 12 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 20089406 Nonpathogen - hypothetical protein MA0517 1 None None None 20092057 Nonpathogen - tRNA 2'-O-methylase MA3241 31 COG1303 COG1303, Uncharacterized protein conserved in archaea Function unknown 20092549 Common leuD 3-isopropylmalate dehydratase MA3751 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 20090911 Nonpathogen - Met-10+ related protein MA2064 36 COG2520 COG2520, Predicted methyltransferase General function prediction only 20091062 Nonpathogen - hypothetical protein MA2222 1 None None None 20092666 Nonpathogen - hypothetical protein MA3870 22 COG2232 COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase General function prediction only 20089268 Nonpathogen - hypothetical protein MA0371 1 None None None 20089309 Common - hypothetical protein MA0416 68 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 20089540 Nonpathogen - hypothetical protein MA0653 4 None None None 20092472 Nonpathogen - hypothetical protein MA3672 23 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 20089176 Nonpathogen tbp-3 transcription factor MA0278 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 20091441 Common - hypothetical protein MA2615 64 COG2013 COG2013, Uncharacterized conserved protein Function unknown 20092537 Common - hypothetical protein MA3739 15 None None None 20092892 Nonpathogen - hypothetical protein MA4099 6 COG1844 COG1844, Uncharacterized protein conserved in archaea Function unknown 20090661 Common - replication factor C large subunit MA1810 153 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 20092509 Common - hypothetical protein MA3710 22 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 20091060 Nonpathogen - hypothetical protein MA2220 14 COG4022 COG4022, Uncharacterized protein conserved in archaea Function unknown 20092102 Common - PmbA/TldD family protein MA3287 160 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 20091591 Nonpathogen - hypothetical protein MA2768 4 None None None 20092078 Common - hypothetical protein MA3262 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 20092672 Common - cell division protein FtsZ MA3876 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 20089049 Common - hypothetical protein MA0151 15 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 20089858 Nonpathogen - hypothetical protein MA0981 4 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 20089873 Common - hypothetical protein MA0996 124 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 20091400 Nonpathogen - hypothetical protein MA2574 8 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 20091457 Nonpathogen - hypothetical protein MA2634 1 None None None 20089765 Common - dipeptide transporter protein DppB MA0881 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20091306 Common - hypothetical protein MA2475 154 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 20092405 Common cpa carboxypeptidase A MA3604 16 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 20092748 Common - transcriptional regulator, ArsR family MA3952 94 COG0640 ArsR, Predicted transcriptional regulators Transcription 20088983 Common - hypothetical protein MA0084 46 COG5607 COG5607, Uncharacterized conserved protein Function unknown 20093293 Nonpathogen - hypothetical protein MA4508 1 None None None 20092115 Nonpathogen - hypothetical protein MA3300 3 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 20092566 Nonpathogen - hypothetical protein MA3768 1 None None None 20089646 Common aepA exoenzyme regulatory protein precursor MA0761 112 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 20090287 Nonpathogen - hypothetical protein MA1427 1 None None None 20090153 Common - hypothetical protein MA1289 83 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 20090810 Common - metallo-beta-lactamase superfamily protein MA1962 53 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 20091127 Nonpathogen - 4-carboxymuconolactone decarboxylase MA2289 10 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 20093388 Common - iron(III) ABC transporter, solute-binding protein HemV2 MA4604 104 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20091701 Nonpathogen fwdD formylmethanofuran dehydrogenase MA2879 15 COG1153 FwdD, Formylmethanofuran dehydrogenase subunit D Energy production and conversion 20090787 Nonpathogen - hypothetical protein MA1938 2 None None None 20090639 Nonpathogen - hypothetical protein MA1788 4 None None None 20093137 Common ilvE branched-chain amino acid aminotransferase MA4349 215 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 20089300 Common isf-3 iron-sulfur flavoprotein MA0406 37 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20093357 Nonpathogen - hypothetical protein MA4573 31 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 20090352 Common - ferredoxin MA1493 34 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 20091443 Nonpathogen - hypothetical protein MA2617 4 COG1895 COG1895, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 20089556 Common fwdG formylmethanofuran dehydrogenase, subunit G MA0671 49 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 20091190 Nonpathogen - hypothetical protein MA2356 1 None None None 20091748 Nonpathogen - hypothetical protein MA2929 1 None None None 20092922 Nonpathogen - hypothetical protein MA4129 1 None None None 20092532 Nonpathogen - hypothetical protein MA3734 10 COG4855 COG4855, Uncharacterized protein conserved in archaea Function unknown 20091297 Nonpathogen - hypothetical protein MA2466 1 None None None 20089861 Nonpathogen - hypothetical protein MA0984 10 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 20091655 Common - hypothetical protein MA2831 34 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 20090965 Common - type I site-specific deoxyribonuclease MA2122 108 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 20089564 Common - hypothetical protein MA0679 21 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 20092679 Nonpathogen - hypothetical protein MA3883 34 COG2016 COG2016, Predicted RNA-binding protein (contains PUA domain) Translation, ribosomal structure and biogenesis 20089684 Common - hypothetical protein MA0800 9 COG3794 PetE, Plastocyanin Energy production and conversion 20091199 Common - hypothetical protein MA2366 30 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 20092950 Nonpathogen atpF V-type ATP synthase subunit F MA4157 16 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 20093219 Common tdk thymidylate kinase MA4433 235 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 20090774 Common - hypothetical protein MA1925 45 None None None 20090139 Common ahcY2 S-adenosyl-L-homocysteine hydrolase MA1275 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 20093217 Nonpathogen - hypothetical protein MA4431 11 COG4048 COG4048, Uncharacterized protein conserved in archaea Function unknown 20092608 Nonpathogen - hypothetical protein MA3812 1 None None None 20092942 Common - hypothetical protein MA4149 5 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 20089015 Common pss CDP-diacylglycerol-serine O-phosphatidyltransferase MA0116 126 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 20091841 Common glmS glucosamine-fructose-6-phosphate aminotransferase (isomerizing) MA3023 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 20089261 Common - transcriptional regulator, TetR family MA0364 111 COG1309 AcrR, Transcriptional regulator Transcription 20089662 Nonpathogen - hypothetical protein MA0778 1 None None None 20092689 Common - hypothetical protein MA3893 37 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 20090670 Common aspB aspartate aminotransferase MA1819 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 20089619 Common - hypothetical protein MA0734 23 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 20090038 Nonpathogen - oligosaccharyltransferase MA1172 18 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 20092962 Nonpathogen - hypothetical protein MA4169 3 None None None 20090830 Common ior indolepyruvate ferredoxin oxidoreductase, subunit alpha MA1982 67 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 20088937 Common - hypothetical protein MA0038 25 COG5496 COG5496, Predicted thioesterase General function prediction only 20092486 Common egsA NAD(P)-dependent glycerol-1-phosphate dehydrogenase MA3686 124 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 20092575 Common rfbB dTDP-glucose 4,6-dehydratase MA3779 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 20093008 Common - glutamine-pyruvate aminotransferase MA4218 210 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 20092021 Nonpathogen - hypothetical protein MA3205 4 None None None 20093400 Nonpathogen - hypothetical protein MA4619 6 COG4742 COG4742, Predicted transcriptional regulator Transcription 20093368 Common - hypothetical protein MA4584 121 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 20089829 Common hemU hemin permease MA0951 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 20091140 Nonpathogen - hypothetical protein MA2302 1 None None None 20090780 Common - hypothetical protein MA1931 28 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 20089821 Common hisS histidyl-tRNA synthetase MA0943 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 20092984 Common - AIR synthase related protein MA4193 76 COG2144 COG2144, Selenophosphate synthetase-related proteins General function prediction only 20090686 Common isf-8 iron-sulfur flavoprotein MA1836 43 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 20092002 Common - moaA/nifB/pqqE family protein MA3185 47 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 20090158 Nonpathogen - hypothetical protein MA1294 1 None None None 20091734 Nonpathogen - hypothetical protein MA2913 1 None None None 20090378 Common - WD-domain containing protein MA1519 65 COG1520 COG1520, FOG: WD40-like repeat Function unknown 20092263 Common - iron ABC transporter, solute-binding protein MA3451 79 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20089382 Common - hypothetical protein MA0493 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 20090086 Common - iron(III) ABC transporter, solute-binding protein MA1222 85 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 20090767 Common - hypothetical protein MA1918 30 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 20090747 Nonpathogen - hypothetical protein MA1897 1 None None None 20092846 Common - alpha-amylase MA4053 23 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 20091859 Nonpathogen - hypothetical protein MA3041 1 None None None 20091825 Common - hypothetical protein MA3007 4 None None None 20092422 Common - GTP-binding protein MA3622 210 COG2262 HflX, GTPases General function prediction only 20090093 Common - hypothetical protein MA1229 11 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 20092033 Common - cysteine protease (papain C1 family) MA3217 25 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 20091471 Common atsA arylsulfatase MA2648 84 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 20091903 Common leuC 3-isopropylmalate dehydratase, large subunit MA3085 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 20091439 Common - serine proteinase inhibitor MA2613 28 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 20090134 Common - sensory transduction histidine kinase MA1270 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 20091868 Common oppC oligopeptide ABC transporter, permease protein MA3050 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 20089395 Nonpathogen - hypothetical protein MA0506 6 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 20091285 Common - hypothetical protein MA2454 24 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 20091473 Common atsA arylsulfatase MA2650 72 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 20089036 Common - dCMP deaminase MA0137 109 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 20092617 Nonpathogen - hypothetical protein MA3821 1 None None None 20093435 Common - hypothetical protein MA4656 149 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism