Salmonella enterica subsp. enterica serovar Typhi str. CT18, complete genome NC_003198 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 16761630 Common hycA formate hydrogenlyase regulatory protein STY2975 7 None None None 16761970 Common - hypothetical protein STY3375 53 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 16762945 Common yjcC hypothetical protein STY4462 163 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 16759808 Common poxB pyruvate dehydrogenase STY0931 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 16759681 Common - hypothetical protein STY0788 14 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 16762668 Common yhjW phosphoethanolamine transferase STY4162 62 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 16759815 Common ybjZ macrolide transporter ATP-binding /permease protein STY0938 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 16759472 Common fsr fosmidomycin resistance protein STY0538 102 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 16762423 Common - hypothetical protein STY3870 132 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16763296 Common sefB fimbrial chaperone protein STY4837 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16759827 Common cydC cysteine/glutathione ABC transporter membrane/ATP-binding component STY0954 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 16762455 Common atpB F0F1 ATP synthase subunit A STY3907 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 16759600 Common ybeA hypothetical protein STY0692 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 16762309 Common coaA pantothenate kinase STY3740 73 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 16759321 Common stbC outer membrane fimbrial usher protein STY0371 37 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16763050 Common - hypothetical protein STY4583 18 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 16759313 Common frsA fermentation/respiration switch protein STY0363 23 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 16761401 Common - hypothetical protein STY2722 11 None None None 16761940 Common - probable alcohol dehydrogenase STY3337 168 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 16761061 Common - hypothetical protein STY2345 5 None None None 16759402 Common - thiamine biosynthesis protein ThiI STY0464 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 16759609 Common - putative hydrolase C-terminus STY0701 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 16762038 Common - hypothetical protein STY3454 74 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 16759930 Common - putative bacteriophage protein STY1069 10 None None None 16760291 Common - putative DNA-binding transcriptional regulator STY1477 69 COG1802 GntR, Transcriptional regulators Transcription 16762900 Common - hypothetical protein STY4415 5 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 16762356 Common - autoinducer-2 (AI-2) modifying protein LsrG STY3791 25 COG1359 COG1359, Uncharacterized conserved protein Function unknown 16759751 Common ompX outer membrane protein X STY0872 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16759878 Common exo exonuclease STY1016 14 None None None 16760803 Pathogen - putative bacteriophage protein STY2059 5 None None None 16761697 Common nlpD predicted outer membrane lipoprotein STY3050 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 16762919 Common dinF DNA-damage-inducible SOS response protein STY4434 145 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 16760798 Common hokW hypothetical protein STY2054 7 None None None 16761645 Pathogen - hypothetical protein found within S. typhi pathogenicity island 1 STY2989 2 None None None 16761966 Common assT probable arylsulfate sulfotransferase STY3370 10 None None None 16762372 Common pfkA 6-phosphofructokinase STY3809 159 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 16761854 Common - hypothetical protein STY3230 18 None None None 16760718 Common - hypothetical protein STY1958 215 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 16763323 Pathogen - hypothetical protein STY4871 1 None None None 16759342 Common foxA ferrioxamine B receptor precursor STY0396 122 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 16762679 Common yhjU hypothetical protein STY4176 18 None None None 16762805 Common gph phosphoglycolate phosphatase STY4314 196 COG0546 Gph, Predicted phosphatases General function prediction only 16761155 Common rtn hypothetical protein STY2451 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16760686 Common gdhA glutamate dehydrogenase STY1922 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 16761945 Pathogen - hypothetical protein STY3344 1 None None None 16759613 Common rihA ribonucleoside hydrolase 1 STY0706 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 16760267 Common - putative phosphotransferase enzyme STY1451 18 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 16762598 Common waaC ADP-heptose:LPS heptosyl transferase I STY4083 90 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 16761506 Common yfiF predicted methyltransferase STY2841 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 16759435 Common ybaX queuosine biosynthesis protein QueC STY0497 174 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 16761639 Common sitB Iron transport protein, ATP-binding component STY2984 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 16759330 Pathogen - possible transcriptionl regulator STY0381 1 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 16759529 Common ykgD hypothetical araC-family transcriptional regulator STY0611 121 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16762239 Common - hypothetical protein STY3665 3 None None None 16761623 Common hycH formate hydrogenlyase maturation protein STY2968 13 None None None 16761187 Common napA probable nitrate reductase STY2485 186 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16761815 Pathogen - hypothetical protein STY3189 2 None None None 16759841 Common pflA pyruvate formate lyase-activating enzyme 1 STY0968 84 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 16762004 Common - hypothetical protein STY3412 40 COG2259 COG2259, Predicted membrane protein Function unknown 16761657 Pathogen - doubtful CDS found within S. typhi pathogenicity island STY3003 1 None None None 16761893 Pathogen - hypothetical protein STY3279 1 None None None 16761437 Common hisS histidyl-tRNA synthetase STY2767 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16763361 Common - hypothetical protein STY4917 14 None None None 16763257 Common mgtA magnesium-transporting ATPase MgtA STY4796 230 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 16761980 Common folB bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase STY3385 100 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 16762155 Common fre FMN reductase STY3580 107 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 16762461 Common atpD F0F1 ATP synthase subunit beta STY3913 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 16760881 Common - putative lipoprotein STY2142 6 None None None 16762112 Pathogen oadG oxaloacetate decarboxylase subunit gamma STY3533 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 16761559 Common iroE hypothetical protein STY2893 30 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 16762822 Common - hypothetical protein STY4337 19 None None None 16760700 Pathogen - hypothetical protein STY1940 1 None None None 16759347 Common prpC methylcitrate synthase STY0401 194 COG0372 GltA, Citrate synthase Energy production and conversion 16762736 Common rpoH RNA polymerase factor sigma-32 STY4243 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 16760956 Common cbiP cobyric acid synthase STY2222 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 161501926 Common gcvR glycine cleavage system transcriptional repressor STY2728 32 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 16763338 Common cstA probable carbon starvation protein STY4890 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 16761179 Common ccmD1 heme exporter protein D1 STY2477 17 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 16763344 Common - hypothetical protein STY4899 52 COG2966 COG2966, Uncharacterized conserved protein Function unknown 16759935 Common - putative DNA invertase (fragment) STY1075 22 None None None 16761172 Pathogen - homolog of virulence protein msgA STY2470 1 None None None 16760225 Common - hypothetical protein STY1402 6 None None None 161501946 Common copR transcriptional regulatory protein YedW STY1128 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16761385 Common - putative ethanolamine utilization protein EutQ STY2704 19 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 16762143 Common yhdG hypothetical protein STY3564 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 16763082 Common - putative phage tail protein STY4617 17 None None None 16759197 Common btuF vitamin B12-transporter protein BtuF STY0228 127 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 16759688 Common pal peptidoglycan-associated outer membrane lipoprotein STY0795 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 16759210 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase STY0243 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 16762242 Common - possible endonuclease STY3668 17 None None None 16763057 Pathogen - hypothetical protein STY4590 3 None None None 16759724 Pathogen - hypothetical protein STY0832 1 None None None 16762993 Pathogen - putative GerE family regulatory protein STY4514 3 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16761620 Common hydN electron transport protein HydN STY2965 154 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 16760893 Common sirA response regulator STY2155 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16763089 Common - putative phage terminase STY4624 18 None None None 16761000 Common - hypothetical protein STY2279 96 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16762075 Common - putative ABC transporter ATP-binding protein YrbF STY3492 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 16760715 Common - hypothetical protein STY1955 125 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16760198 Common pspC DNA-binding transcriptional activator STY1373 27 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 16759153 Common - probable secreted protein STY0179 18 None None None 16761841 Common - Z-ring-associated protein STY3216 45 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 16762488 Common dnaN DNA polymerase III subunit beta STY3941 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 16760833 Common yebG DNA damage-inducible protein YebG STY2088 19 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 16761005 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase STY2283 216 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 16762865 Common rpsM 30S ribosomal protein S13 STY4380 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 16763032 Common - hypothetical protein STY4563 21 None None None 16760538 Common sufA iron-sulfur cluster assembly scaffold protein STY1754 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 16759533 Common - hypothetical protein STY0615 6 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 16762777 Common - gluconate periplasmic binding protein STY4286 166 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 16760310 Common osmC osmotically inducible protein C STY1497 80 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 16762916 Common plsB glycerol-3-phosphate acyltransferase STY4431 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 16762424 Common typA GTP-binding protein STY3871 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 16761818 Common - possible integrase STY3193 53 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16761485 Common - 2-dehydropantoate 2-reductase STY2819 121 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 16762585 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase STY4070 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 16760678 Pathogen - hypothetical protein STY1911 2 None None None 16761511 Common yfiM hypothetical protein STY2846 13 COG5544 COG5544, Predicted periplasmic lipoprotein General function prediction only 16759352 Common - putative DNA-binding transcriptional regulator STY0406 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16762234 Common cI repressor protein STY3660 11 COG2932 COG2932, Predicted transcriptional regulator Transcription 16760445 Common tus DNA replication terminus site-binding protein STY1652 14 None None None 16759118 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase STY0143 207 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 16759410 Common thiJ hypothetical protein STY0472 59 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 16759096 Common araD L-ribulose-5-phosphate 4-epimerase STY0118 110 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16763039 Common - putative lipoprotein STY4571 21 None None None 16759409 Common phnX phosphonoacetaldehyde phosphonohydrolase STY0471 27 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 16760800 Common - putative transposase STY2056 19 None None None 16762135 Common yhdH possible oxidoreductase STY3556 88 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 16761334 Common mntH manganese transport protein MntH STY2649 109 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 16761646 Common orgAb cell invasion protein STY2990 5 None None None 16759617 Common ybeJ glutamate and aspartate transporter subunit STY0710 157 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16761234 Common yfbB acyl-CoA thioester hydrolase YfbB STY2538 61 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 16759411 Common apbA 2-dehydropantoate 2-reductase STY0473 111 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 16762205 Common rffA TDP-4-oxo-6-deoxy-D-glucose transaminase STY3630 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 16759548 Common entF enterobactin synthase subunit F STY0631 216 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 16760707 Common rnd ribonuclease D STY1947 120 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 16762042 Common yhbV hypothetical protein STY3458 47 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 16762497 Common - hypothetical protein STY3950 6 None None None 16762018 Common garL alpha-dehydro-beta-deoxy-D-glucarate aldolase STY3431 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 16760694 Common - hypothetical protein STY1933 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 16762148 Common hemG protoporphyrinogen oxidase STY3573 37 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 16762166 Common udp uridine phosphorylase STY3591 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 16762847 Common rpsS 30S ribosomal protein S19 STY4362 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 16760991 Common - hypothetical protein STY2264 22 COG2926 COG2926, Uncharacterized protein conserved in bacteria Function unknown 16762997 Common - Putative acetyltransferase STY4518 46 COG3153 COG3153, Predicted acetyltransferase General function prediction only 16760856 Common - hypothetical protein STY2114 54 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 16761889 Common nupG nucleoside permease STY3268 36 None None None 16761249 Common nuoF NADH dehydrogenase I subunit F STY2554 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 16762578 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase STY4063 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 16763174 Common yjeS putative 4Fe-4S binding protein STY4712 136 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 16761654 Common iagB cell invasion protein STY3000 32 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16759466 Common htpG heat shock protein 90 STY0531 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 16760331 Common hyaD2 hydrogenase 1 maturation protease STY1527 78 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 16761500 Common nadB L-aspartate oxidase STY2834 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 16762304 Common rplK 50S ribosomal protein L11 STY3736 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 16761442 Common - putative polyferredoxin STY2772 5 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 16760973 Common pduC glycerol dehydratase large subunit STY2245 13 COG4909 PduC, Propanediol dehydratase, large subunit Secondary metabolites biosynthesis, transport, and catabolism 16759923 Common - putative bacteriophage protein STY1062 8 None None None 16760821 Common - putative excisionase STY2076 4 None None None 16762870 Common yhdN hypothetical protein STY4385 25 None None None 16761038 Common wcaH putative O-antigen biosynthesis protein STY2319 17 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 16760463 Common pdxY pyridoxamine kinase STY1672 62 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 16759384 Common yajC preprotein translocase subunit YajC STY0444 166 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 16759190 Common fhuC iron-hydroxamate transporter ATP-binding subunit STY0219 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 16762023 Common - PTS system, sugar phosphotransferase enzyme IIBC component STY3437 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 16763117 Common vexA Vi polysaccharide export protein STY4655 55 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 16761757 Common fucR DNA-binding transcriptional activator STY3119 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16761595 Common emrA multidrug resistance protein A STY2940 150 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16760681 Common hyaD hydrogenase 1 maturation protease STY1916 72 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 16759798 Common artM arginine transporter permease subunit ArtM STY0921 171 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 16762251 Common - major capsid protein STY3677 22 None None None 16760124 Common narJ respiratory nitrate reductase 1 delta chain STY1290 54 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 16760210 Common - putative transcriptional regulator STY1386 164 COG0583 LysR, Transcriptional regulator Transcription 16761138 Common sdaC putative L-serine dehydratase STY2430 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 16762177 Common pldA phospholipase A STY3602 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 16761666 Common spaQ secretory protein (associated with virulence) STY3012 24 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 16761868 Common endA endonuclease I STY3246 33 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 16762250 Common - putative capsid scaffolding protein STY3676 22 None None None 16762270 Common - probable major tail sheath protein STY3696 39 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 16762257 Common - hypothetical protein STY3683 3 None None None 16759099 Common araC DNA-binding transcriptional regulator AraC STY0121 128 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16759458 Common - potassium efflux protein KefA STY0522 224 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16761196 Common yojN phosphotransfer intermediate protein in two-component regulatory system with RcsBC STY2494 86 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16759901 Common - putative prophage membrane protein STY1040 8 None None None 16759541 Common ramA transcriptional activator RamA STY0624 82 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 16759838 Pathogen - hypothetical protein STY0965 1 None None None 16760165 Common - hypothetical protein STY1335 13 None None None 16762701 Common - putative phosphosugar-binding protein STY4202 88 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 16762893 Pathogen - hypothetical protein STY4408 1 None None None 16761554 Common - putative bacteriophage major tail sheath protein STY2888 39 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 16763078 Common - probable phage baseplate assembly protein STY4613 38 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 16760274 Common - putative benzoate membrane transport protein STY1458 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 16761379 Common eutG putative alchohol dehydrogenase STY2698 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 16762884 Common yjaB hypothetical protein STY4399 63 COG0456 RimI, Acetyltransferases General function prediction only 16759957 Common mgsA methylglyoxal synthase STY1098 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 16761064 Common - hypothetical protein STY2348 6 None None None 16763114 Common vexD Vi polysaccharide export inner-membrane protein STY4652 35 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 16761362 Common cysP thiosulfate transporter subunit STY2681 88 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 16759083 Common apaH diadenosine tetraphosphatase STY0103 105 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 16762983 Common dcuB anaerobic C4-dicarboxylate transporter STY4500 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 16761320 Common pgtE outer membrane protease STY2632 12 COG4571 OmpT, Outer membrane protease Cell envelope biogenesis, outer membrane 16760082 Common - putative lipoprotein STY1247 22 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 16761880 Common - hypothetical protein STY3258 3 None None None 16762708 Common - inner membrane transporter YhiP STY4211 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 16759634 Common citB citrate utilization protein B STY0728 22 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 16762228 Common ilvE branched-chain amino acid aminotransferase STY3654 220 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 16760366 Common dmsC putative dimethyl sulphoxide reductase subunit STY1568 27 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 16759183 Common pcnB poly(A) polymerase I STY0209 211 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 16762549 Common - putative transferase STY4017 73 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 16760050 Common flgB flagellar basal body rod protein FlgB STY1213 99 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 16760817 Common recE exonuclease VIII STY2073 9 None None None 16762271 Common - probable major tail tube protein STY3697 26 COG3498 COG3498, Phage tail tube protein FII General function prediction only 16759016 Common bcfB fimbrial chaperone STY0025 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16762927 Common dnaB replicative DNA helicase STY4442 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 16760055 Common flgG flagellar basal body rod protein FlgG STY1218 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 16762528 Common - probable permease STY3990 45 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 16762682 Common - hypothetical protein STY4179 9 None None None 16759079 Common - hypothetical protein STY0099 5 None None None 16761765 Common - hypothetical protein STY3127 219 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 16761535 Common ppnK inorganic polyphosphate/ATP-NAD kinase STY2869 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 16762907 Common - phosphate-starvation-inducible protein PsiE STY4422 20 COG3223 COG3223, Predicted membrane protein Function unknown 16759987 Common hpaA 4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein STY1142 89 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16759363 Common adrA adrA protein STY0418 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 16759088 Common imp organic solvent tolerance protein STY0108 119 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 16759043 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase STY0058 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 16759671 Common sdhC succinate dehydrogenase cytochrome b556 large membrane subunit STY0775 88 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 16760076 Common tdk thymidylate kinase STY1239 228 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 16760632 Common - hypothetical protein STY1859 44 None None None 16761008 Common hisF imidazole glycerol phosphate synthase subunit HisF STY2286 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 16762346 Common menG ribonuclease activity regulator protein RraA STY3781 66 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 16759396 Common - thiamine monophosphate kinase STY0458 200 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 16763066 Common - putative positive regulator of late gene transcription STY4600 10 None None None 16760776 Common - putative bacteriophage protein STY2033 6 None None None 16761315 Common fadL long-chain fatty acid outer membrane transporter STY2623 81 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 16759026 Common - possible sulfatase STY0039 11 None None None 16760137 Common oppB oligopeptide transporter permease STY1305 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16759207 Common tsf elongation factor Ts STY0240 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 16759350 Common hemB delta-aminolevulinic acid dehydratase STY0404 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 16760978 Common pduJ putative propanediol utilization protein PduJ STY2250 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 16761959 Common - hypothetical protein STY3362 26 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 16762293 Common thiC thiamine biosynthesis protein ThiC STY3721 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 16762393 Common yiiG putative lipoprotein STY3836 9 COG5373 COG5373, Predicted membrane protein Function unknown 16760905 Common fliS flagellar protein FliS STY2169 92 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 16761285 Common - putative amino acid decarboxylase STY2590 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 16759771 Common yliI putative oxidoreductase STY0894 118 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 16761307 Common mepA penicillin-insensitive murein endopeptidase STY2615 39 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 16761387 Common eutS putative ethanolamine utilization protein EutS STY2706 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 16762687 Common yhjK hypothetical protein STY4188 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16760393 Common - hypothetical protein STY1598 3 None None None 16761919 Common - hypothetical protein STY3312 17 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 16760761 Pathogen - putative bacteriophage protein STY2018 2 None None None 16759176 Common staF putative fimbrial protein STY0202 5 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760511 Common sseC putative pathogenicity island effector protein STY1720 7 COG5613 COG5613, Uncharacterized conserved protein Function unknown 16760849 Common yebC hypothetical protein STY2107 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 16759337 Pathogen - hypothetical protein STY0391 1 None None None 16760041 Common grxB glutaredoxin 2 STY1203 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 16761563 Common virK virulence protein STY2899 21 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 16759306 Common yafJ hypothetical protein STY0356 74 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 16760914 Common fliG flagellar motor switch protein G STY2178 123 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 16762493 Common - putative membrane transport protein STY3946 142 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16761924 Common hybD predicted maturation element for hydrogenase 2 STY3317 80 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 16763377 Common creA hypothetical protein STY4934 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 16762821 Common yheU hypothetical protein STY4334 31 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 16761271 Common - hypothetical protein STY2576 23 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 16760526 Common ttrC tetrathionate reductase subunit C (membrane protein) STY1737 18 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 16761229 Common - hypothetical protein STY2533 5 None None None 16760919 Common fliL flagellar basal body-associated protein FliL STY2183 32 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 16760665 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase STY1897 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 16761800 Common - probable amino acid transport protein STY3167 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16762647 Common bax hypothetical protein STY4135 31 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 16762609 Common secB preprotein translocase subunit SecB STY4094 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 16761054 Common yegD putative chaperone STY2338 229 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 16759651 Common phrB deoxyribodipyrimidine photolyase STY0749 135 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 16759055 Common citF2 citrate lyase alpha chain STY0070 29 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 16760879 Common - hypothetical protein STY2140 103 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 16762096 Common codA cytosine deaminase STY3514 71 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 16759053 Common citD2 citrate lyase subunit gamma STY0068 26 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 16761785 Common - possible oxidoreductase STY3151 192 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 16760432 Common - alternative bacteriophage tail fiber C-terminus STY1638 19 None None None 16762329 Common metF 5,10-methylenetetrahydrofolate reductase STY3761 154 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 16762979 Common melR DNA-binding transcriptional dual regulator STY4496 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16763010 Common ssB single-strand DNA-binding protein STY4536 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 16759642 Common pgm phosphoglucomutase STY0736 200 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 16760276 Common - putative peptidase STY1460 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 16759434 Common - hypothetical protein STY0496 22 COG0824 FcbC, Predicted thioesterase General function prediction only 16759516 Common fimA type-1 fimbrial protein, a chain precursor STY0589 20 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760106 Common phoP DNA-binding response regulator in two-component regulatory system with PhoQ STY1271 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16762566 Common recG ATP-dependent DNA helicase RecG STY4048 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 16759295 Common tcfA putative fimbrial protein STY0345 8 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16760498 Common ssaM putative pathogenicity island protein STY1707 4 None None None 16761185 Common napH quinol dehydrogenase membrane component STY2483 59 COG0348 NapH, Polyferredoxin Energy production and conversion 16759262 Common - hypothetical protein STY0297 49 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 16760447 Common fumA Fumarate hydratase class I, aerobic STY1654 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 16762785 Common ompR osmolarity response regulator STY4294 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16760412 Common - putative bacteriophage protein STY1618 19 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 16760482 Common sodB superoxide dismutase STY1691 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 16762635 Common lyxK putative L-xylulose kinase STY4122 178 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16760175 Common osmB lipoprotein STY1346 7 None None None 16761021 Common rfbS paratose synthase STY2299 40 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16761344 Common - putative transcriptional regulator STY2660 192 COG0583 LysR, Transcriptional regulator Transcription 16761777 Common tnpA transposase for insertion sequence element IS200 STY3140 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760142 Common cls cardiolipin synthetase STY1312 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 16760872 Common motA flagellar motor protein MotA STY2132 121 COG1291 MotA, Flagellar motor component Cell motility and secretion 16761093 Common stcB putative fimbrial chaperone protein STY2380 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16762591 Common waaB UDP-D-galactose:(glucosyl)lipopolysaccharide-1,6-D-galactosyltransferase STY4076 159 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16759477 Common cueR DNA-binding transcriptional activator of copper-responsive regulon genes STY0545 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 16762694 Common yhjD hypothetical protein STY4195 27 COG1295 Rbn, Predicted membrane protein Function unknown 16762666 Common tag 3-methyl-adenine DNA glycosylase I STY4160 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 16760630 Common aadA aminoglycoside-resistance protein STY1857 24 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 16763326 Common - putative sugar transport protein STY4874 153 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16763046 Pathogen - hypothetical protein STY4578 3 None None None 16760264 Common - putative phosphotransferase enzyme STY1448 42 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 16760191 Common - DNA-invertase (fragment) STY1366 67 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 16761708 Common iap aminopeptidase in alkaline phosphatase isozyme conversion STY3061 26 COG2234 Iap, Predicted aminopeptidases General function prediction only 16759255 Common - hypothetical protein STY0290 23 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 16761143 Common yeiH hypothetical protein STY2437 110 COG2855 COG2855, Predicted membrane protein Function unknown 16762685 Common yhjN cellulose synthase regulator protein STY4182 21 None None None 16759977 Common - hypothetical protein STY1129 64 COG2351 COG2351, Transthyretin-like protein General function prediction only 16762739 Common livK leucine-specific binding protein STY4248 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 16760468 Common slyB outer membrane lipoprotein SlyB precursor STY1677 24 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 16760945 Common amn AMP nucleosidase STY2211 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 16761299 Common - putative DNA-binding protein STY2605 26 COG3423 Nlp, Predicted transcriptional regulator Transcription 16763380 Common creD hypothetical protein STY4937 29 COG4452 CreD, Inner membrane protein involved in colicin E2 resistance Defense mechanisms 16763238 Common pmbA peptidase PmbA STY4777 158 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 16761351 Common ptsH phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr) STY2667 138 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 16762627 Common selB selenocysteinyl-tRNA-specific translation factor STY4114 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 16761292 Common dedA hypothetical protein STY2598 172 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 16759508 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit STY0581 192 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 16762376 Common cpxA two-component sensor protein STY3813 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16760232 Common - C32 tRNA thiolase STY1412 166 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 16760154 Common trpA tryptophan synthase subunit alpha STY1324 212 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 16761084 Common - putative nucleoside permease STY2371 56 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16759864 Common ycbB hypothetical protein STY0997 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 16760536 Common sufC cysteine desulfurase ATPase component STY1752 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 16760353 Common - putative regulatory protein STY1551 127 COG1802 GntR, Transcriptional regulators Transcription 16760395 Pathogen - hypothetical protein STY1600 1 None None None 16759563 Common - hypothetical protein STY0648 19 COG1475 Spo0J, Predicted transcriptional regulators Transcription 16762164 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase STY3589 222 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 16760373 Common bioD putative dithiobiotin synthetase STY1575 145 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 16763291 Common - hypothetical protein STY4830 3 None None None 16760565 Pathogen - hypothetical protein STY1782 1 None None None 16761498 Common rseA anti-RNA polymerase sigma factor SigE STY2832 32 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 16761257 Common - hypothetical protein STY2562 32 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 16760736 Common - hypothetical protein STY1979 53 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 16762835 Common rpsL 30S ribosomal protein S12 STY4350 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 16760163 Common - short chain dehydrogenase STY1333 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16760493 Common ssaQ type III secretion system protein STY1702 6 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 16762387 Common rhaA L-rhamnose isomerase STY3827 23 COG4806 RhaA, L-rhamnose isomerase Carbohydrate transport and metabolism 16762745 Common ugpB glycerol-3-phosphate transporter periplasmic binding protein STY4254 104 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 16761589 Common nrdE ribonucleotide-diphosphate reductase subunit alpha STY2932 218 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 16760297 Common - N-hydroxyarylamine O-acetyltransferase STY1483 45 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 16761358 Common cysM cysteine synthase B STY2677 230 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 16761867 Common - hypothetical protein STY3245 26 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 16759239 Common metN DL-methionine transporter ATP-binding subunit STY0274 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 16763386 Common arcA DNA-binding response regulator in two-component regulatory system with ArcB or CpxA STY4947 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16763161 Common blc outer membrane lipoprotein Blc STY4699 69 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 16762249 Common - terminase, ATPase subunit STY3675 25 COG5484 COG5484, Uncharacterized conserved protein Function unknown 16761720 Common cysJ sulfite reductase subunit alpha STY3076 97 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 16759843 Common pflB formate acetyltransferase 1 STY0973 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 16759131 Common secA preprotein translocase subunit SecA STY0156 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 16761577 Common - hypothetical protein STY2916 36 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 16760997 Common sbcB exonuclease I STY2276 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 16762473 Common pstC phosphate transporter permease subunit STY3927 225 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 16760865 Common cheY chemotaxis regulator transmitting signal to flagellar motor component STY2125 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 16762182 Common corA magnesium/nickel/cobalt transporter CorA STY3607 146 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 16762405 Common yiiD putative acetyltransferase STY3849 48 COG2153 ElaA, Predicted acyltransferase General function prediction only 16762442 Common rbsB D-ribose transporter subunit RbsB STY3894 134 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 16763091 Common - putative capsid protein STY4626 22 None None None 16763016 Common pilQ nucleotide-binding protein STY4545 198 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 16762816 Common pabA para-aminobenzoate synthase component II STY4327 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 16760098 Common potC spermidine/putrescine ABC transporter membrane protein STY1263 208 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 16760936 Common - hypothetical protein STY2202 3 None None None 16762613 Common - putative lacI family transcriptional regulator regulator STY4100 126 COG1609 PurR, Transcriptional regulators Transcription 16761545 Pathogen - putative reverse transcriptase STY2879 2 None None None 16761043 Common wcaC predicted glycosyl transferase STY2326 22 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16761475 Common yfhA putative transcriptional regulator STY2809 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 161501937 Pathogen asr acid shock protein precursor STY1582 1 None None None 16759622 Common miaB MiaB protein (putative tRNA-thiotransferase (or tRNA-methylthiotransferase)) STY0716 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 16761114 Common yohG multidrug resistance outer membrane protein MdtQ STY2402 107 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16761470 Common cadC DNA-binding transcriptional activator STY2804 60 COG3710 CadC, DNA-binding winged-HTH domains Transcription 16760091 Common mfd transcription-repair coupling factor STY1256 233 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 16762620 Common yibL hypothetical protein STY4107 13 None None None 16761204 Common nrdB ribonucleotide-diphosphate reductase subunit beta STY2507 154 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 16759636 Common - lysR-family transcriptional regulator STY0730 186 COG0583 LysR, Transcriptional regulator Transcription 16762840 Common bfr bacterioferritin, iron storage and detoxification protein STY4355 106 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 16760748 Common - hypothetical protein STY2000 141 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 16760419 Common - bacteriophage tail sheath protein STY1625 47 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 16761163 Common yejD 16S rRNA pseudouridylate synthase A STY2459 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 16762070 Common - hypothetical protein STY3487 73 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 16759887 Pathogen - conserved hypothetical bacteriophage protein STY1025 3 None None None 16762082 Common rpoN RNA polymerase factor sigma-54 STY3499 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 16761480 Common yfhC tRNA-specific adenosine deaminase STY2814 217 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 16760047 Common flgN flagella synthesis protein FlgN STY1210 13 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 16760596 Common gdhA glutamate dehydrogenase STY1815 174 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 16759101 Common thiQ thiamin transporter ATP-binding subunit STY0123 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 16762653 Common glyQ glycyl-tRNA synthetase subunit alpha STY4143 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 16759856 Common - hypothetical protein STY0989 97 COG2835 COG2835, Uncharacterized conserved protein Function unknown 16761873 Common kdgR probable global regulatory protein STY3251 7 COG1414 IclR, Transcriptional regulator Transcription 16759676 Common sucB dihydrolipoamide acetyltransferase STY0780 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 16759173 Common panC pantoate--beta-alanine ligase STY0199 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 16759285 Common - hypothetical protein STY0326 8 None None None 16760149 Common - outer membrane protein W STY1319 71 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 16762970 Common phnB hypothetical protein STY4487 63 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 16758998 Common yaaA hypothetical protein STY0005 89 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 16759719 Common bioB biotin synthetase STY0827 181 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 16759163 Common yacC hypothetical protein STY0189 11 None None None 16760981 Common pduM hypothetical protein STY2253 8 None None None 16762367 Common - aminoimidazole riboside kinase STY3804 206 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16763267 Common - arginine deiminase STY4805 54 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 16762197 Common hemD uroporphyrinogen-III synthase STY3622 46 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 16760528 Common - Orf 245 protein STY1741 10 COG5426 COG5426, Uncharacterized membrane protein Function unknown 16759774 Common deoR DNA-binding transcriptional repressor STY0897 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16760454 Common - Na(+)-translocating NADH-quinone reductase subunit E STY1663 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 16762214 Common trxA thioredoxin STY3639 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 16761718 Common cysH phosphoadenosine phosphosulfate reductase STY3074 156 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 16761603 Common alaS alanyl-tRNA synthetase STY2948 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16759226 Common - hypothetical protein STY0260 41 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 16761768 Common argA N-acetylglutamate synthase STY3130 205 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 16760306 Common adhP alcohol dehydrogenase STY1493 211 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 16763243 Common - hypothetical protein STY4782 11 None None None 16761126 Common sanA hypothetical protein STY2414 40 COG2949 SanA, Uncharacterized membrane protein Function unknown 16759230 Common yaeQ hypothetical protein STY0264 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 16763342 Common dnaT primosomal protein I STY4897 8 COG5529 COG5529, Pyocin large subunit General function prediction only 16760643 Common - putative heat shock protein STY1871 75 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 16760101 Common potA putrescine/spermidine ABC transporter ATPase protein STY1266 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 16759662 Common - putative glycosyl transferase STY0760 24 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 16759733 Common ybhO cardiolipin synthase 2 STY0847 145 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 16762248 Common - probable capsid portal protein STY3674 28 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 16761732 Pathogen - possible secreted protein STY3091 1 None None None 16762509 Common dsbE2 thiol:disulfide interchange protein STY3965 117 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16763026 Common - hypothetical protein STY4557 15 None None None 16761127 Common - hypothetical protein STY2415 4 None None None 16762902 Common pgi glucose-6-phosphate isomerase STY4417 197 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 16759248 Common - hypothetical protein STY0283 55 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 16759491 Common ybbB tRNA 2-selenouridine synthase STY0561 65 COG2603 COG2603, Predicted ATPase General function prediction only 16762265 Common - probable variable tail fibre protein STY3691 35 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 16762430 Pathogen - hypothetical protein STY3879 2 None None None 16761746 Common queF 7-cyano-7-deazaguanine reductase STY3107 83 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 16763055 Pathogen - hypothetical protein STY4588 2 None None None 16762395 Common fdhD formate dehydrogenase accessory protein STY3838 135 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 16761265 Common - putative transketolase C-terminal section STY2570 222 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 16761429 Common xseA exodeoxyribonuclease VII large subunit STY2753 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 16760626 Pathogen - hypothetical protein STY1853 1 None None None 16761752 Common fucA L-fuculose phosphate aldolase STY3113 156 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16761937 Common metC cystathionine beta-lyase STY3333 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 16762966 Common yjcO hypothetical protein STY4483 58 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 16759001 Common mogA molybdenum cofactor biosynthesis protein STY0008 184 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 16762923 Common - hypothetical protein STY4438 10 None None None 16759962 Common - putative transcriptional regulator (pseudogene) STY1106 56 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16760256 Pathogen sseJ secreted effector J (pseudogene) STY1439a 1 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 16761035 Common manB phosphomannomutase STY2316 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 16759890 Pathogen - putative bacteriophage protein STY1028 2 None None None 16761106 Common yehX ABC transporter ATP-binding protein STY2393 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 16763278 Common - leucyl aminopeptidase STY4816 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 16759944 Common pqiA putative inner membrane protein STY1084 56 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 16761458 Common yfhP DNA-binding transcriptional repressor STY2790 160 COG1959 COG1959, Predicted transcriptional regulator Transcription 16763347 Common - hypothetical protein STY4902 100 COG2606 EbsC, Uncharacterized conserved protein Function unknown 16763231 Common ytfP hypothetical protein STY4770 30 COG2105 COG2105, Uncharacterized conserved protein Function unknown 16759166 Common hpt hypoxanthine-guanine phosphoribosyltransferase STY0192 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 16760645 Pathogen - putative lipoprotein STY1874 1 None None None 16760828 Common - hypothetical protein STY2083 11 COG0388 COG0388, Predicted amidohydrolase General function prediction only 16761398 Common acrD aminoglycoside/multidrug efflux system STY2719 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 16759572 Common - molybdopterin-containing oxidoreductase iron-sulfur subunit STY0660 166 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 161501902 Common ulaA ascorbate-specific PTS system enzyme IIC STY4739 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 16761391 Common tktB transketolase STY2711 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 16763128 Common - probable phage integrase STY4666 117 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16761102 Common yehU putative two-component system sensor kinase STY2389 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 16760385 Common - hypothetical protein STY1590 11 None None None 16760324 Common pqaA hypothetical protein STY1518 14 COG4287 PqaA, PhoPQ-activated pathogenicity-related protein General function prediction only 16762764 Common glgX glycogen debranching enzyme STY4273 152 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 16763225 Common ytfK hypothetical protein STY4764 16 None None None 16759550 Common fepG iron-enterobactin transporter permease STY0635 191 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 16761600 Common - hypothetical protein STY2945 73 COG1238 COG1238, Predicted membrane protein Function unknown 16763321 Common - hypothetical protein STY4869 12 COG0700 SpmB, Uncharacterized membrane protein Function unknown 16760318 Common - putative aminotransferase STY1507 233 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 16763024 Pathogen pilK hypothetical protein STY4553 3 None None None 16760925 Common fliR flagellar biosynthesis protein FliR STY2189 119 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 16760900 Common fliY cystine transporter subunit STY2162 190 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16760579 Common celF phospho-beta-glucosidase B STY1797 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 16762947 Common soxR SoxR protein STY4464 87 COG0789 SoxR, Predicted transcriptional regulators Transcription 16762354 Common tpiA triosephosphate isomerase STY3789 231 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 16761170 Common sspH2 secreted effector protein STY2467 33 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 16759062 Common caiE carnitine operon protein CaiE STY0079 193 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 16762105 Common rplM 50S ribosomal protein L13 STY3525 240 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 16761887 Common - hypothetical protein STY3266 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 16760012 Common - putative 2-hydroxyacid dehydrogenase in phoh-csgg intergenic region STY1172 228 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 16762952 Common - hypothetical protein STY4469 26 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 16761676 Common invF possible AraC-family regulatory protein STY3022 8 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16759584 Common citC [citrate (pro-3S)-lyase] ligase STY0673 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 16759574 Common ybdQ hypothetical protein STY0662 61 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 16760228 Common ogt O-6-alkylguanine-DNA:cysteine-protein methyltransferase STY1405 187 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 16760615 Common - putative bacteriophage protein STY1841 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 16762778 Common bioH carboxylesterase BioH STY4287 146 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 16761891 Pathogen - hypothetical protein STY3277 1 None None None 16762959 Common nrfB cytochrome c-type protein NrfB STY4476 19 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 16762533 Common uhpT sugar phosphate antiporter STY3995 44 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16759767 Common yliC hypothetical ABC transporter permease protein STY0889 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16760780 Common - hypothetical protein STY2037 18 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 16763168 Common yjeN hypothetical protein STY4706 2 None None None 16759690 Common nadA quinolinate synthetase STY0797 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 16763103 Common - hypothetical protein STY4640 6 None None None 16760574 Common - putative sodium:dicarboxylate symporter STY1791 155 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 16761071 Pathogen - hypothetical protein STY2356 1 None None None 16762540 Common - putative PTS system phosphocarrier protein STY4004 91 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 16762755 Common - putative ribokinase STY4264 190 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16762458 Common atpH F0F1 ATP synthase subunit delta STY3910 179 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 16761618 Common - nitric oxide reductase STY2963 229 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 16762319 Common argH argininosuccinate lyase STY3750 232 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 16761420 Common ppx exopolyphosphatase STY2743 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 16759424 Common ampG muropeptide transporter STY0486 109 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759997 Common wrbA TrpR binding protein WrbA STY1155 104 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 16762886 Common aceB malate synthase STY4401 79 COG2225 AceB, Malate synthase Energy production and conversion 16760016 Common csgG assembly/transport component in curli production STY1176 17 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 16761453 Common hscA chaperone protein HscA STY2785 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 16761931 Common - hypothetical protein STY3328 3 None None None 16762555 Common slsA hypothetical protein STY4025 65 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 16762434 Common dsbA periplasmic protein disulfide isomerase I STY3883 61 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 16760789 Pathogen - hypothetical protein STY2046 1 None None None 16763137 Pathogen - hypothetical protein STY4675 1 None None None 16762127 Common tldD TldD protein STY3548 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 16760031 Common yceE drug efflux system protein MdtG STY1191 75 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759076 Pathogen - hypothetical protein STY0096 1 None None None 16763353 Common rimI ribosomal-protein-alanine N-acetyltransferase STY4908 204 COG0456 RimI, Acetyltransferases General function prediction only 16763357 Pathogen - hypothetical protein STY4912 1 COG5487 COG5487, Small integral membrane protein Function unknown 16762449 Common asnA asparagine synthetase AsnA STY3901 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 16763186 Common yjeB transcriptional repressor NsrR STY4724 159 COG1959 COG1959, Predicted transcriptional regulator Transcription 16762310 Common birA biotin--protein ligase STY3741 230 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 16763130 Common - hypothetical protein STY4668 45 COG3153 COG3153, Predicted acetyltransferase General function prediction only 16760531 Common lppA major outer membrane lipoprotein STY1745 19 COG4238 COG4238, Murein lipoprotein Cell envelope biogenesis, outer membrane 16763154 Common yjeJ hypothetical protein STY4692 5 None None None 16760060 Common flgL flagellar hook-associated protein FlgL STY1223 105 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 16762077 Common - D-arabinose 5-phosphate isomerase STY3494 151 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 16762905 Common - hypothetical protein STY4420 15 None None None 16759831 Common ftsK DNA translocase FtsK STY0958 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 16761791 Common lysA diaminopimelate decarboxylase STY3157 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 16760891 Common pgsA phosphatidylglycerophosphate synthetase STY2153 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 16760559 Common rplT 50S ribosomal protein L20 STY1775 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 16761665 Common spaR secretory protein (associated with virulence) STY3011 52 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 16762344 Common hslU ATP-dependent protease ATP-binding subunit STY3779 213 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 16760312 Common - hypothetical protein STY1499 3 None None None 16761483 Common murQ N-acetylmuramic acid-6-phosphate etherase STY2817 88 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 16761681 Pathogen - hypothetical protein STY3031 1 None None None 16760036 Common solA N-methyltryptophan oxidase STY1198 60 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 16761002 Common hisG ATP phosphoribosyltransferase STY2280 205 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 16762954 Common actP acetate permease STY4471 166 COG4147 DhlC, Predicted symporter General function prediction only 16759105 Common leuD isopropylmalate isomerase small subunit STY0129 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 16759568 Common ahpF alkyl hydroperoxide reductase F52A protein (subunit F) STY0655 247 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 16762160 Common tatB sec-independent translocase STY3585 31 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 16761198 Common rcsC hybrid sensory kinase in two-component regulatory system with RcsB and YojN STY2496 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16761895 Common - bacteriocin immunity protein STY3283 8 None None None 16759065 Common caiB crotonobetainyl-CoA:carnitine CoA-transferase STY0082 111 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 16760135 Common - hypothetical protein STY1303 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 16762914 Common ubiC chorismate pyruvate lyase STY4429 21 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 16760657 Common msgA putative virulence protein STY1883 8 None None None 16762193 Pathogen - hypothetical protein STY3618 1 None None None 16759726 Common moaA molybdenum cofactor biosynthesis protein A STY0836 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 16760589 Common astB succinylarginine dihydrolase STY1808 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 16762499 Common torT periplasmic sensory protein associated with the TorRS two-component regulatory system STY3952 19 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 16761242 Common nuoM NADH dehydrogenase subunit M STY2547 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 16761031 Common - hypothetical protein STY2309 5 None None None 16761253 Common nuoA NADH dehydrogenase subunit A STY2558 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 16759126 Common ftsQ cell division protein FtsQ STY0151 83 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 16763119 Common insB insertion element IS1 protein InsB STY4657 21 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 16762940 Common - putative type-I secretion protein STY4457 109 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16762133 Common mreB rod shape-determining protein STY3554 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 16759619 Common - haemolysin-related protein STY0712 220 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 16759195 Common yadR hypothetical protein STY0226 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 16759413 Common - hpothetical major facilitator family transport protein STY0475 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762933 Pathogen - hypothetical protein STY4448 2 None None None 16760285 Common srfB putative virulence effector protein STY1471 14 COG4457 SrfB, Uncharacterized protein conserved in bacteria, putative virulence factor Function unknown 16760293 Common - possible ATP-binding protein STY1479 46 COG3391 COG3391, Uncharacterized conserved protein Function unknown 16759686 Common tolA cell envelope integrity inner membrane protein TolA STY0793 18 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 16759615 Common gltK glutamate/aspartate transport system permease protein GltK STY0708 180 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 16762044 Common - tryptophan permease STY3460 31 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16760544 Common aroD 3-dehydroquinate dehydratase STY1760 53 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 16759459 Common - hypothetical protein STY0523 31 COG5464 COG5464, Uncharacterized conserved protein Function unknown 16762141 Common panF sodium/panthothenate symporter STY3562 168 COG4145 PanF, Na+/panthothenate symporter Coenzyme metabolism 16761180 Common ccmC1 heme exporter protein C1 STY2478 125 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 16760676 Common pth peptidyl-tRNA hydrolase STY1909 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 16762876 Common def peptide deformylase STY4391 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 16762380 Common - possible membrane transport protein STY3819 52 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 16761592 Common proX glycine betaine transporter periplasmic subunit STY2937 51 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 16759407 Common phnR probable regulator of 2-aminoethylphosphonate uptake and metabolism operon STY0469 125 COG2188 PhnF, Transcriptional regulators Transcription 16759531 Common - hypothetical secreted protein STY0613 3 None None None 16762485 Common rnpA ribonuclease P STY3939 70 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 16761838 Common visB 2-octaprenyl-6-methoxyphenyl hydroxylase STY3213 120 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 16762158 Common tatD DNase TatD STY3583 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 16761982 Common - O-sialoglycoprotein endopeptidase STY3387 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 16761659 Pathogen sipA pathogenicity island 1 effector protein (function unknown) STY3005 3 None None None 16760516 Common ssaD putative pathogenicity island protein STY1725 10 None None None 16762917 Common dgkA diacylglycerol kinase STY4432 109 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 16760801 Pathogen - hypothetical protein STY2057 2 None None None 16761149 Common - hypothetical protein STY2444 3 None None None 16762153 Common fadA 3-ketoacyl-CoA thiolase STY3578 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 16763271 Common miaE tRNA hydroxylase STY4809 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 16760519 Common ssrA putative two-component sensor kinase STY1728 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16759648 Common kdpB potassium-transporting ATPase B chain STY0746 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 16762063 Common obgE GTPase ObgE STY3480 227 COG0536 Obg, Predicted GTPase General function prediction only 16759538 Common nfnB dihydropteridine reductase STY0620 83 COG0778 NfnB, Nitroreductase Energy production and conversion 16762738 Common yhhK hypothetical protein STY4247 13 None None None 16759311 Common pepD aminoacyl-histidine dipeptidase precursor STY0361 64 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 16759918 Common - putative bacteriophage protein STY1057 7 None None None 16759325 Pathogen - hypothetical protein STY0375 1 None None None 16761643 Pathogen sprB possible AraC-family transcriptional regulator STY2987 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16759921 Common - putative bacteriophage protein STY1060 7 None None None 16759806 Common - hypothetical protein STY0929 83 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16761906 Common - hypothetical protein STY3296 5 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 16762298 Common thiH thiamine biosynthesis protein ThiH STY3726 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 16761699 Common surE stationary phase survival protein SurE STY3052 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 16761852 Common epd D-erythrose 4-phosphate dehydrogenase STY3228 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 161501941 Common - putative aldehyde dehydrogenase STY1467 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16759116 Common ftsL cell division protein FtsL STY0141 25 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 16759222 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha STY0255 196 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 16762370 Common cdh CDP-diacylglycerol pyrophosphatase STY3807 19 COG2134 Cdh, CDP-diacylglycerol pyrophosphatase Lipid metabolism 16759597 Common rlpA rare lipoprotein A STY0689 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 16763325 Common - hypothetical protein STY4873 49 COG2733 COG2733, Predicted membrane protein Function unknown 16759024 Common - putative transcriptional regulator (lysR family) STY0036 91 COG0583 LysR, Transcriptional regulator Transcription 16760067 Common rpmF 50S ribosomal protein L32 STY1230 88 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 16760181 Common - hypothetical protein STY1353 2 None None None 16759527 Common gtrA bactoprenol-linked glucose translocase STY0607 8 COG2246 COG2246, Predicted membrane protein Function unknown 16761637 Common ygbA hypothetical protein STY2982 20 None None None 16760212 Common - oxidoreductase STY1389 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16760796 Pathogen - putative bacteriophage cohesive ends STY2053 1 None None None 16762563 Common yicH hypothetical protein STY4045 13 None None None 16759969 Common pipB hypothetical protein STY1117 65 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 16760269 Common rimL ribosomal-protein-L7/L12-serine acetyltransferase STY1453 68 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 16761028 Common rfbD dTDP-4-dehydrorhamnose reductase STY2306 171 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 16761383 Common eutD phosphotransacetylase STY2702 162 COG0280 Pta, Phosphotransacetylase Energy production and conversion 16759876 Common - putative DNA methylase STY1014 98 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 16761400 Common dapE succinyl-diaminopimelate desuccinylase STY2721 213 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 16761813 Common - hypothetical protein STY3186 24 None None None 16763157 Pathogen ecnA entericidin A precursor STY4695 1 COG5510 COG5510, Predicted small secreted protein Function unknown 16762114 Common ttdA tartrate dehydratase subunit alpha STY3535 130 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 16763215 Common cycA D-alanine/D-serine/glycine permease STY4754 161 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 16759344 Common - hypothetical protein STY0398 7 None None None 16761942 Common - hypothetical protein STY3341 118 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 16762414 Common yihQ alpha-glucosidase STY3859 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 16763255 Common treB trehalose(maltose)-specific PTS system components IIBC STY4794 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 16760932 Common yedA hypothetical protein STY2198 72 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 16759456 Common acrA acriflavin resistance protein A precursor STY0520 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 16762335 Common metL bifunctional aspartate kinase II/homoserine dehydrogenase II STY3768 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 16762173 Common pldB lysophospholipase L2 STY3598 68 COG2267 PldB, Lysophospholipase Lipid metabolism 16763134 Common - hypothetical protein STY4672 3 None None None 16763150 Common yjeH inner membrane protein YjeH STY4688 40 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16761142 Common yeiE putative DNA-binding transcriptional regulator STY2436 186 COG0583 LysR, Transcriptional regulator Transcription 16762463 Common - hypothetical protein STY3915 13 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 161501909 Common yidZ DNA-binding transcriptional regulator YidZ STY3935 85 COG0583 LysR, Transcriptional regulator Transcription 16760954 Common cobS cobalamin synthase STY2220 127 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 16759014 Common - hypothetical protein STY0021 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16760770 Common - putative bacteriophage protein STY2027 7 None None None 16760201 Common - putative ATP-binding protein STY1376 42 COG3106 COG3106, Predicted ATPase General function prediction only 16761939 Common - probable AraC-family trancriptional regulatory protein STY3335 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16763064 Common umuC DNA polymerase V subunit UmuC STY4597 181 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 16762002 Common - hypothetical protein STY3410 10 COG5393 COG5393, Predicted membrane protein Function unknown 16759862 Common mukE condesin subunit E STY0995 20 COG3095 MukE, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 16762725 Common - hypothetical protein STY4232 80 COG1738 COG1738, Uncharacterized conserved protein Function unknown 16761525 Common yfiN hypothetical protein STY2859 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 16759012 Pathogen - hypothetical protein STY0019 1 None None None 16761926 Common hybB predicted hydrogenase 2 cytochrome b type component STY3319 29 COG5557 COG5557, Polysulphide reductase Energy production and conversion 16759145 Common - putatuve glycosysl hydrolase STY0170 23 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 16760610 Common - hypothetical protein STY1832 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 16760617 Common - hypothetical protein STY1843 17 COG3042 Hlx, Putative hemolysin General function prediction only 16762581 Common rpmB 50S ribosomal protein L28 STY4066 157 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 16759399 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase STY0461 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 16760634 Common - putative ABC transport ATP-binding subunit STY1861 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 16761565 Common tctE putative two-component system sensor kinase STY2903 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16760671 Common lolB outer membrane lipoprotein LolB STY1904 53 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 16761313 Common fadI 3-ketoacyl-CoA thiolase STY2621 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 16762571 Common - hypothetical protein STY4056 116 COG2860 COG2860, Predicted membrane protein Function unknown 16759090 Common rluA 23S rRNA/tRNA pseudouridine synthase A STY0110 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16760478 Common gloA glyoxalase I STY1687 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 16760711 Common - putative ATP-dependent helicase STY1951 148 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 16761537 Common smpA hypothetical protein STY2871 59 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 16760334 Common hyaF2 hydrogenase-1 operon protein HyaF2 STY1530 83 COG1773 COG1773, Rubredoxin Energy production and conversion 16761273 Common - putative glutathione-S transferase STY2578 54 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16760423 Common - putative bacteriophage protein STY1629 36 COG5283 COG5283, Phage-related tail protein Function unknown 16759908 Common - putative prophage terminase large subunit STY1047 27 COG1783 XtmB, Phage terminase large subunit General function prediction only 16762107 Common - cytochrome d ubiquinol oxidase subunit III STY3527 24 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 16761625 Common hycF formate hydrogenlyase complex iron-sulfur subunit STY2970 196 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 16763196 Common yjfO hypothetical protein STY4735 9 None None None 16762273 Common - hypothetical protein STY3699 8 None None None 16760371 Common - putative ABC transporter ATP/GTP-binding protein STY1573 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 16760554 Common btuC vtamin B12-transporter permease STY1770 190 COG4139 BtuC, ABC-type cobalamin transport system, permease component Coenzyme metabolism 16759398 Common - putative oxidoreductase STY0460 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 16759821 Pathogen - hypothetical protein STY0947 1 None None None 16761011 Common ugd UDP-glucose 6-dehydrogenase STY2289 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 16762516 Common yidG hypothetical protein STY3975 6 None None None 16760599 Common - putative nitroreductase STY1818 78 COG0778 NfnB, Nitroreductase Energy production and conversion 16760449 Common - hypothetical protein STY1656 21 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 16760850 Common ntpA dATP pyrophosphohydrolase STY2108 41 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16761617 Common - anaerobic nitric oxide reductase flavorubredoxin STY2962 126 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 16760057 Common flgI flagellar basal body P-ring protein STY1220 104 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 16762495 Common - hypothetical protein STY3948 9 None None None 16762202 Common rffT putative enterobacterial common antigen polymerase STY3627 13 None None None 16760903 Common fliC flagellin STY2167 115 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 16760767 Common - putative bacteriophage protein STY2024 6 None None None 16760786 Pathogen - putative bacteriophage protein STY2043 2 None None None 16761739 Common ygcX probable glucarate dehydratase 1 STY3098 55 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16759493 Common allR DNA-binding transcriptional repressor STY0564 122 COG1414 IclR, Transcriptional regulator Transcription 16759333 Pathogen - hypothetical protein STY0385 1 None None None 16759335 Common - putative metabolite transport protein STY0387 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16760417 Common - hypothetical protein STY1623 7 None None None 16761467 Common hcaT putative 3-phenylpropionic acid transporter STY2801 76 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759178 Common staD putative fimbrial protein STY0204 3 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16759693 Common - probable secreted protein STY0800 6 None None None 16760172 Common - hypothetical protein STY1343 74 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 16763071 Common - putative phage tail protein STY4605 19 None None None 16762181 Common yigF hypothetical protein STY3606 8 None None None 16760043 Common rimJ ribosomal-protein-S5-alanine N-acetyltransferase STY1205 90 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 16762526 Common - putative DeoR-family transcriptional regulator STY3988 77 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16762467 Common stgB fimbrial chaperone protein STY3919 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16763375 Common gpmB phosphoglycerate mutase STY4932 176 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 16761542 Common - putative type I secretion protein STY2876 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16759845 Common - hypothetical protein STY0975 43 COG1944 COG1944, Uncharacterized conserved protein Function unknown 16762999 Common - hypothetical protein STY4521 97 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 16762796 Common yrfC hypothetical protein STY4305 6 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 16762680 Common - hypothetical protein STY4177 6 None None None 16761927 Common hybA hydrogenase 2 protein HybA STY3320 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16759968 Pathogen pipA hypothetical protein STY1115 1 None None None 16761491 Common recO DNA repair protein RecO STY2825 86 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 16760844 Common ruvB Holliday junction DNA helicase B STY2102 237 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 16760683 Common hyaF hydrogenase-1 operon protein HyaF STY1918 20 None None None 16762813 Common ppiA peptidyl-prolyl cis-trans isomerase A (rotamase A) STY4324 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 16760705 Common minD cell division inhibitor MinD STY1945 145 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 16760561 Common infC translation initiation factor IF-3 STY1777 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 16759323 Common stbA probable fimbrial protein STY0373 19 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760744 Common - hypothetical protein STY1990 3 None None None 16760993 Common sbmC DNA gyrase inhibitor STY2266 18 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 16762125 Common - hypothetical protein STY3546a 13 None None None 16762895 Common yjbC 23S rRNA pseudouridine synthase F STY4410 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 16760152 Common - hypothetical protein STY1322 38 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 16761440 Common yfgB hypothetical protein STY2770 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 16762995 Pathogen - hypothetical protein STY4516 1 None None None 16762015 Common tdcA DNA-binding transcriptional activator STY3428 184 COG0583 LysR, Transcriptional regulator Transcription 16761807 Common stdA probable fimbrial protein STY3177 20 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16762624 Common mtlA mannitol-specific enzyme II of phosphotransferase system STY4111 69 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 16759371 Common yajF fructokinase STY0426 166 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 16760346 Common - O-acetylserine/cysteine export protein STY1543 73 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 16763311 Common - hypothetical protein STY4859 7 None None None 16761377 Common eutA reactivating factor for ethanolamine ammonia lyase STY2696 17 COG4819 EutA, Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition Amino acid transport and metabolism 16760122 Common narG respiratory nitrate reductase 1 alpha chain STY1288 116 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 16761730 Common steE fimbrial subunit STY3089 10 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760080 Common - purine nucleoside phosphoramidase STY1245 223 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 16759520 Common fimF predicted fimbrial-like adhesin protein STY0595 12 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16761444 Common - putative anaerobic reductase component STY2774 165 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16759464 Common ybaB hypothetical protein STY0529 103 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 16760465 Common pdxH pyridoxamine 5'-phosphate oxidase STY1674 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 16760750 Common - hypothetical protein STY2002 15 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 16762706 Common prlC oligopeptidase A STY4209 126 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 16762168 Common - putative regulatory protein STY3593 86 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 16759951 Common ompA outer membrane protein A STY1091 146 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 16761759 Common ygdD hypothetical protein STY3121 70 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 16762398 Common fdoI formate dehydrogenase-O subunit gamma STY3842 69 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 16763223 Common cysQ PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase STY4762 180 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 16761583 Common ygaC hypothetical protein STY2924 8 None None None 16762253 Common - putative capsid completion protein STY3679 17 None None None 16761136 Common yeiG putative esterase STY2428 97 COG0627 COG0627, Predicted esterase General function prediction only 16759355 Common yaiW putative lipoprotein STY0409 18 None None None 16763116 Common vexB Vi polysaccharide export inner-membrane protein (ABC-2 type transporter) STY4654 34 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 16759081 Common kefC glutathione-regulated potassium-efflux system protein KefC STY0101 197 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 16760383 Common pntB pyridine nucleotide transhydrogenase STY1588 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 16759543 Common - hypothetical protein STY0626 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 16763209 Common priB primosomal replication protein N STY4748 25 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 16762925 Common pspG phage shock protein G STY4440 6 None None None 16763176 Common yjeE putative ATPase STY4714 207 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 16760863 Common flhB flagellar biosynthesis protein FlhB STY2123 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 16761364 Common - hypothetical protein STY2683 51 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 16759667 Common nei endonuclease VIII STY0771 165 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 16761651 Common prgH pathogenicity 1 island effector protein STY2995 7 None None None 16761108 Common yehZ putative periplasmic protein STY2395 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 16762188 Common yifL putative lipoprotein STY3613 7 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 16760858 Common - hypothetical protein STY2116 20 COG3102 COG3102, Uncharacterized protein conserved in bacteria Function unknown 16762179 Common - chloramphenicol-sensitive protein RarD STY3604 112 COG2962 RarD, Predicted permeases General function prediction only 16763246 Common - hypothetical protein STY4785 73 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 16759086 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase STY0106 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 16762226 Common ilvA threonine dehydratase STY3652 222 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 16762170 Common metR trans-activator of metE and metH STY3595 183 COG0583 LysR, Transcriptional regulator Transcription 16760582 Common celB N,N'-diacetylchitobiose-specific PTS system transporter subunit IIC STY1800 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 16761502 Common srmB ATP-dependent RNA helicase SrmB STY2836 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 16761911 Common - possible hydrolase STY3303 127 COG0388 COG0388, Predicted amidohydrolase General function prediction only 16759373 Common sbcD exonuclease subunit SbcD STY0430 108 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 16762542 Common nepI ribonucleoside transporter STY4008 109 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762615 Common lldD L-lactate dehydrogenase STY4102 130 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 16760846 Pathogen - hypothetical protein STY2104 1 None None None 16761112 Common yohD hypothetical protein STY2400 96 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 16759780 Common - hypothetical protein STY0903 57 COG2985 COG2985, Predicted permease General function prediction only 16761206 Common - putative transmembrane transport protein STY2509 154 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759057 Common citG2 citg protein STY0072 48 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 16759536 Common ybdG hypothetical protein STY0618 90 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16762440 Common rbsR transcriptional repressor RbsR STY3891 129 COG1609 PurR, Transcriptional regulators Transcription 16759576 Common rnk nucleoside diphosphate kinase regulator STY0664 75 COG0782 GreA, Transcription elongation factor Transcription 16762047 Common pnp polynucleotide phosphorylase/polyadenylase STY3463 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 16760119 Common narL DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) STY1285 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16762212 Common rfe putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase STY3637 152 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 16761770 Common RecB exonuclease V subunit beta STY3132 218 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 16762611 Common cysE serine acetyltransferase STY4096 211 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 16759357 Common - hypothetical protein STY0411 6 None None None 16762622 Common mtlR mannitol repressor protein STY4109 18 COG3722 MtlR, Transcriptional regulator Transcription 16763301 Common - helicase related protein STY4849 68 COG1201 Lhr, Lhr-like helicases General function prediction only 16762537 Common - putative PTS system IIB component STY3999 18 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 16761298 Pathogen - putative bacteriophage protein STY2604 5 None None None 16761575 Common gabP gamma-aminobutyrate transporter STY2913 172 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 16761861 Common speB agmatinase STY3238 153 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 161501948 Common lipB lipoyltransferase STY0686 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 16759194 Common yadQ chloride channel protein STY0225 147 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 16759624 Common asnB asparagine synthetase B STY0718 159 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 16760749 Pathogen - hypothetical protein STY2001 2 None None None 16762814 Common yhfG hypothetical protein STY4325 6 None None None 16760934 Common dcm DNA cytosine methylase STY2200 119 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 16763139 Pathogen - hypothetical protein STY4677 1 None None None 16763132 Common - hypothetical protein STY4670 6 None None None 16762349 Common glpK glycerol kinase STY3784 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 16759858 Common - hypothetical protein STY0991 10 None None None 16763084 Common - hypothetical protein STY4619 3 None None None 16761023 Common rfbG CDP-glucose 4,6-dehydratase STY2301 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16759283 Pathogen - hypothetical protein STY0323 1 None None None 16763093 Common - probable capsid portal protein STY4628 25 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 16759470 Common gsk inosine-guanosine kinase STY0535 58 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16760971 Common pduA putative propanediol utilization protein PduA STY2243 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 16762583 Common mutM formamidopyrimidine-DNA glycosylase STY4068 183 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 16759784 Common nfsA nitroreductase A STY0907 66 COG0778 NfnB, Nitroreductase Energy production and conversion 16761875 Common - hypothetical protein STY3253 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 16762199 Common hemY putative protoheme IX biogenesis protein STY3624 52 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 16762068 Common nlp DNA-binding transcriptional activator of maltose metabolism STY3485 22 COG3423 Nlp, Predicted transcriptional regulator Transcription 16763265 Common - ornithine carbamoyltransferase STY4803 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 16761701 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase STY3054 187 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 16758996 Common thrB homoserine kinase STY0003 104 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 16759717 Common ybhB predicted kinase inhibitor STY0825 112 COG1881 COG1881, Phospholipid-binding protein General function prediction only 16759103 Common tbpA thiamin transporter substrate binding subunit STY0125 53 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 16763263 Common - putative transcriptional regulator STY4801 72 COG1438 ArgR, Arginine repressor Transcription 16759274 Common - hypothetical protein STY0313 2 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 16760167 Common cysB transcriptional regulator CysB STY1337 186 COG0583 LysR, Transcriptional regulator Transcription 16762080 Common - hypothetical protein STY3497 66 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 16760473 Common sodC superoxide dismutase STY1682 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 16759889 Common - hypothetical bacteriophage protein STY1027 8 None None None 16759638 Common fldA flavodoxin FldA STY0732 74 COG0716 FldA, Flavodoxins Energy production and conversion 16762079 Common - hypothetical protein STY3496 25 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 16760728 Common - hypothetical protein STY1969 9 None None None 16760147 Common yciC hypothetical protein STY1317 15 None None None 16760456 Common - electron transport complex protein RnfC STY1665 111 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 16763125 Common - hypothetical protein STY4663 5 None None None 16760742 Pathogen - hypothetical protein STY1986 1 None None None 16760987 Common - putative propanediol utilization protein PduU STY2260 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 16760270 Common - putative transferase STY1454 9 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 16760309 Common - biofilm-dependent modulation protein STY1496 4 None None None 16762072 Common - possible exported protein STY3489 78 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 16760134 Common adh alcohol dehydrogenase STY1302 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 16759161 Common speD S-adenosylmethionine decarboxylase STY0187 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 16763018 Common pilS prepilin STY4547 4 None None None 16759678 Common sucD succinyl-CoA synthetase subunit alpha STY0782 215 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 16762191 Common cyaY frataxin-like protein STY3616 44 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 16761605 Common recA recombinase A STY2950 223 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 16761342 Common xapA purine nucleoside phosphorylase STY2658 159 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 16762645 Common avtA valine--pyruvate transaminase STY4133 166 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 16761703 Common ftsB cell divison protein FtsB STY3056 62 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 16763188 Common yjfH 23S rRNA (guanosine-2'-O-)-methyltransferase STY4726 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 16763006 Common - hypothetical protein STY4529 21 None None None 16761690 Common - putative aldolase STY3041 110 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16761507 Common yfiG thioredoxin 2 STY2842 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 16761779 Common lgt prolipoprotein diacylglyceryl transferase STY3143 204 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 16763147 Common aspA aspartate ammonia-lyase STY4685 220 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 16760874 Common flhD transcriptional activator FlhD STY2134 27 None None None 16760088 Common - putative TetR-family regulatory protein STY1253 103 COG1309 AcrR, Transcriptional regulator Transcription 16760279 Pathogen ugtL hypothetical protein STY1463 1 None None None 16762977 Common adiY putative AraC family regulatory protein STY4494 6 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16761787 Common aas bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase STY3153 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16762607 Common - putative secreted protein STY4092 102 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 16762849 Common rpsC 30S ribosomal protein S3 STY4364 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 16763364 Common deoB phosphopentomutase STY4920 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 16759748 Common glnH glutamine ABC transporter periplasmic protein STY0868 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16762518 Common dsdA D-serine dehydratase STY3977 37 COG3048 DsdA, D-serine dehydratase Amino acid transport and metabolism 16761353 Common - hypothetical protein STY2671 4 None None None 161501935 Common - hypothetical protein STY1790 38 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 16760112 Common rluB putative ribosomal large subunit pseudouridine synthase B STY1277 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 16760177 Common - RNase II stability modulator STY1349 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 16760989 Common - propionate kinase STY2262 161 COG0282 ackA, Acetate kinase Energy production and conversion 16759246 Common mltD predicted membrane-bound lytic murein transglycosylase D STY0281 150 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16763369 Common serB phosphoserine phosphatase STY4925 153 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 16761930 Common - hypothetical protein STY3326 55 COG2862 COG2862, Predicted membrane protein Function unknown 16763351 Common rsmC 16S ribosomal RNA m2G1207 methyltransferase STY4906 148 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 16761550 Common - putative bacteriophage tail protein STY2884 32 COG5283 COG5283, Phage-related tail protein Function unknown 161501920 Common tolC outer membrane channel protein STY3364 136 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16759514 Common ybcJ hypothetical protein STY0587 31 COG2501 COG2501, Uncharacterized conserved protein Function unknown 16763328 Pathogen - hypothetical protein STY4878 1 None None None 16760183 Common sapF peptide transport system ATP-binding protein SapF STY1355 249 COG4167 SapF, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 16762637 Common insB insertion element IS1 protein InsB STY4125 21 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 16759033 Common nhaA pH-dependent sodium/proton antiporter STY0047 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 16762402 Common - putative lipase STY3846 128 COG0657 Aes, Esterase/lipase Lipid metabolism 16763007 Common topB DNA topoisomerase III STY4530 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 16761748 Common sdaC putative serine transporter STY3109 36 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16762662 Common yiaE 2-hydroxyacid dehydrogenase STY4156 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 16759432 Common ppiD peptidyl-prolyl cis-trans isomerase (rotamase D) STY0494 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 16761086 Common - putative sugar kinase STY2373 133 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16760410 Common - hypothetical protein STY1616 29 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 16759658 Common - probable DNA recombinase STY0756 206 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16760193 Common sapB peptide transport system permease protein SapB STY1368 218 COG4168 SapB, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 16762855 Common rplE 50S ribosomal protein L5 STY4370 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 16761830 Common - hypothetical protein STY3205 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 16762220 Common - hypothetical protein STY3645 6 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16760325 Common - membrane transport protein STY1519 207 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16762664 Common bisC biotin sulfoxide reductase STY4158 174 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16759293 Common sinR LysR-family transcriptional regulator SinR STY0341 143 COG0583 LysR, Transcriptional regulator Transcription 16759038 Common - hypothetical protein STY0053 3 None None None 16762683 Common yhjQ cell division protein STY4180 15 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 16760230 Common - putative chemo-receptor protein STY1408 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 16760404 Common - hypothetical protein STY1610 9 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 16759045 Common yaaF ribonucleoside hydrolase RihC STY0060 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 16763298 Pathogen - probable regulatory protein STY4842 1 None None None 16759268 Common - hypothetical protein STY0305 147 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 16761302 Common - hypothetical protein STY2608 27 None None None 16762787 Common pckA phosphoenolpyruvate carboxykinase STY4296 96 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 16762374 Common cpxP periplasmic repressor CpxP STY3811 17 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 16761960 Common nudF ADP-ribose pyrophosphatase NudF STY3363 77 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 16762630 Common - hypothetical protein STY4117 32 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 16761684 Common - hypothetical protein STY3034 8 COG4460 COG4460, Uncharacterized protein conserved in bacteria Function unknown 16759299 Common tinR transcriptional regulator STY0349 148 COG1522 Lrp, Transcriptional regulators Transcription 16759253 Common - hypothetical protein STY0288 42 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 16762530 Common uhpA DNA-binding response regulator in two-component regulatory system wtih UhpB STY3992 182 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16759505 Common - hypothetical protein STY0578 17 None None None 16762931 Common - hypothetical protein STY4446 77 COG0432 COG0432, Uncharacterized conserved protein Function unknown 16760939 Common umuC DNA polymerase V subunit UmuC STY2205 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 16762299 Common rpoC DNA-directed RNA polymerase subunit beta' STY3731 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 16760688 Common - hypothetical protein STY1926 20 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 16760568 Common pfkB 6-phosphofructokinase 2 STY1785 137 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 16760998 Common yeeF putative amino acid transporter protein STY2277 161 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16762204 Common - putative lipopolysaccharide biosynthesis protein STY3629 22 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 16759483 Common ybbO short chain dehydrogenase STY0551 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 16761843 Common serA D-3-phosphoglycerate dehydrogenase STY3218 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 16759769 Common yliG hypothetical protein STY0891 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 16762409 Common yihW putative DeoR-family transcriptional regulator STY3853 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16760609 Common - hypothetical protein STY1831 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 16763355 Common prfC peptide chain release factor 3 STY4910 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 16759587 Common dcuC C4-dicarboxylate transporter DcuC STY0676 23 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 16760075 Common - hypothetical protein STY1238 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 16763140 Common int integrase (fragment) STY4678 65 None None None 16760014 Common - hypothetical protein STY1174 20 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 16759897 Common - hypothetical protein STY1035 11 None None None 16759981 Common hpaG 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase STY1134 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 16760295 Common ansP L-asparagine permease STY1481 170 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 16761729 Common steD fimbrial subunit STY3088 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16759060 Common carB carbamoyl phosphate synthase large subunit STY0077 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 16763101 Common - hypothetical protein STY4638 5 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 16761522 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase STY2856 86 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 16763314 Common uxuR DNA-binding transcriptional repressor STY4862 143 COG2186 FadR, Transcriptional regulators Transcription 16759365 Common yaiI hypothetical protein STY0420 96 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 16759760 Common ybiW putative formate acetyltransferase 3 STY0882 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 16761674 Common invE cell invasion protein STY3020 8 None None None 16762320 Common argB acetylglutamate kinase STY3751 207 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 16759237 Common metQ DL-methionine transporter substrate-binding subunit STY0272 101 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 16761323 Common pgtC phosphoglycerate transport regulatory protein PgtC precursor STY2635 54 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 16761543 Common - putative type I secretion protein, ATP-binding protein STY2877 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 16761214 Common - deubiquitinase STY2517 2 None None None 16760968 Common cbiA cobyrinic acid a,c-diamide synthase STY2240 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 16762677 Common yhjV putative amino acid permease STY4173 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16761189 Common napF ferredoxin-type protein STY2487 60 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 16761513 Common - hypothetical protein STY2848 11 None None None 16762352 Common yiiR hypothetical protein STY3787 17 COG3152 COG3152, Predicted membrane protein Function unknown 16759704 Common modE DNA-binding transcriptional dual regulator STY0812 59 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 16761045 Common wzc tyrosine kinase STY2329 149 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 16760916 Common fliI flagellum-specific ATP synthase STY2180 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 16760963 Common cbiF precorrin-4 C11-methyltransferase STY2234 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 16759475 Common - probable secreted protein STY0543 4 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 16760028 Common mdoH glucosyltransferase MdoH STY1188 53 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 16760018 Common csgE curli assembly protein CsgE STY1178 10 None None None 16762365 Common - putative GntR-family regulatory protein STY3802 111 COG2188 PhnF, Transcriptional regulators Transcription 16761232 Common menC O-succinylbenzoate synthase STY2536 72 COG1441 MenC, O-succinylbenzoate synthase Coenzyme metabolism 16761414 Common - DNA replication initiation factor STY2737 163 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 16760033 Common - hypothetical protein STY1193 133 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 16759995 Common agp glucose-1-phosphatase/inositol phosphatase STY1153 17 None None None 16759386 Common secF preprotein translocase subunit SecF STY0446 220 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 16763159 Common ecnR transcriptional regulatory protein STY4697 12 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16759439 Common - putative lyase STY0501 210 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 16762302 Common rplJ 50S ribosomal protein L10 STY3734 188 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 16762557 Common rmbA hypothetical protein STY4032 4 None None None 16759137 Common coaE dephospho-CoA kinase STY0162 203 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 16760533 Common - cysteine desufuration protein SufE STY1749 93 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 16762432 Common polA DNA polymerase I STY3881 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 16762412 Common yihT putative aldolase STY3856 25 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 16762743 Common livF leucine/isoleucine/valine transporter ATP-binding subunit STY4252 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 16761161 Pathogen - hypothetical protein STY2457 1 None None None 16760923 Common fliP flagellar biosynthesis protein FliP STY2187 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 16760495 Pathogen ssaO putative type III secretion protein STY1704 1 None None None 16763198 Common yjfQ probable transcriptional regulator STY4737 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16762138 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit STY3559 192 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 16760007 Common - N-acetylmannosamine-6-phosphate 2-epimerase STY1166 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 16760650 Pathogen - hypothetical protein STY1877 1 None None None 16761806 Common stdB probable outer membrane fimbrial usher protein STY3176 27 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16762094 Common - hypothetical protein STY3512 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 16763152 Common groEL chaperonin GroEL STY4690 245 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 16762550 Common - hypothetical protein STY4018 15 None None None 16762976 Common - arginine:agmatin antiporter STY4493 185 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16762507 Common ccmE2 cytochrome c-type biogenesis protein CcmE STY3963 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 16762986 Common dcuS sensory histidine kinase DcuS STY4502 204 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 16760308 Common rpsV 30S ribosomal subunit S22 STY1495 5 None None None 16760888 Common - hypothetical protein STY2149 23 None None None 16759219 Common lpxB lipid-A-disaccharide synthase STY0252 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 16760621 Pathogen - hypothetical protein STY1848 2 None None None 16761754 Common fucI L-fucose isomerase STY3116 19 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 16760364 Common dmsA2 putative dimethyl sulphoxide reductase subunit STY1566 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16761392 Pathogen - hypothetical protein STY2712 1 None None None 16760598 Common selD selenophosphate synthetase STY1817 136 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 16760692 Common dadX alanine racemase STY1930 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 16762267 Common - hypothetical protein STY3693 8 None None None 16760831 Common yebE hypothetical protein STY2086 32 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 16759664 Common - putative polysaccharide export ABC transporter ATP-binding protein STY0764 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 16759566 Common dsbG disulfide isomerase/thiol-disulfide oxidase STY0652 24 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 16759303 Common - hypothetical protein STY0353 191 COG0388 COG0388, Predicted amidohydrolase General function prediction only 16759224 Common - putative secreted chitinase STY0257 26 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 16759003 Common - hypothetical protein STY0010 10 COG4735 COG4735, Uncharacterized protein conserved in bacteria Function unknown 16759892 Pathogen - putative bacteriophage protein STY1030 2 None None None 16760756 Common - putative bacteriophage tail protein STY2013 8 None None None 16761528 Common rimM 16S rRNA-processing protein STY2862 179 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 16761570 Common - hypothetical protein STY2908 77 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 16760602 Common pncA nicotinamidase/pyrazinamidase STY1821 119 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 16762535 Common - putative GntR-family transcriptional regulator STY3997 138 COG2188 PhnF, Transcriptional regulators Transcription 16760206 Common - putative mandelate racemase / muconate lactonizing enzyme family protein STY1382 101 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16760583 Common celA N,N'-diacetylchitobiose-specific PTS system transporter subunit IIB STY1801 28 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 16761611 Common srlD sorbitol-6-phosphate dehydrogenase STY2956 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16761714 Common - hypothetical protein STY3069 10 None None None 16759942 Common - hypothetical protein STY1082 163 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 16761824 Common dsbC thiol:disulfide interchange protein DsbC STY3199 67 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 16759421 Common cyoC cytochrome o ubiquinol oxidase subunit III STY0483 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 16760003 Common phoH hypothetical protein STY1162 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 16762001 Common - hypothetical protein STY3409 9 COG4575 ElaB, Uncharacterized conserved protein Function unknown 16760504 Pathogen ssaH putative pathogenicity island protein STY1713 1 None None None 16760349 Common - competence damage-inducible protein A STY1547 154 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 16763371 Common nadR nicotinamide-nucleotide adenylyltransferase STY4927 31 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 16762771 Common glpR DNA-binding transcriptional repressor STY4280 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16760647 Pathogen - hypothetical protein STY1874b 1 None None None 16760659 Common - hypothetical protein STY1887 9 None None None 16762602 Common tdh L-threonine 3-dehydrogenase STY4087 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 16762246 Common - hypothetical protein STY3672 4 None None None 16759448 Common ylaB hypothetical 58.9 kDa protein in tesb-hha intergenic region. Contains probable N-terminal signal sequence STY0511 162 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 16759829 Common trxB thioredoxin reductase STY0956 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 16761439 Common yfgA hypothetical protein STY2769 47 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 16762968 Common - putative membrane-bound beta-hydroxylase STY4485 37 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 16762244 Pathogen - possible lipoprotein STY3670 1 None None None 16762056 Common glmM phosphoglucosamine mutase STY3472 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 16759114 Common yabB hypothetical protein STY0139 144 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 16760160 Common - hypothetical protein STY1330 220 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 16760062 Common rne ribonuclease E STY1226 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 16760254 Common - putative periplasmic amino acid-binding protein STY1438 152 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16762629 Common aldB aldehyde dehydrogenase B STY4116 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16761226 Common - hypothetical protein STY2530 19 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 16761168 Common yejL hypothetical protein STY2465 18 COG3082 COG3082, Uncharacterized protein conserved in bacteria Function unknown 16761041 Common wcaF putative colanic acid biosynthesis acetyltransferase WcaF STY2322 135 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 16759595 Common ybeD hypothetical protein STY0687 48 COG2921 COG2921, Uncharacterized conserved protein Function unknown 16759461 Common ybaN hypothetical protein STY0526 36 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 16760826 Common - hypothetical protein STY2081 44 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 16762331 Common - alanine racemase STY3763 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 16759905 Pathogen - hypothetical protein STY1044 1 None None None 16762069 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase STY3486 218 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 16761100 Common yehS hypothetical protein STY2387 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 16759966 Common - hypothetical protein STY1112 129 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 16762296 Common thiS sulfur carrier protein ThiS STY3724 15 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 16762880 Common yrdC putative ribosome maturation factor STY4395 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 16761904 Common - hypothetical protein STY3294 6 None None None 16760208 Common mppA periplasmic murein peptide-binding protein MppA STY1384 200 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 16761634 Common hypD hydrogenase isoenzyme formation protein HypD STY2979 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 16761324 Common pgtP phosphoglycerate transporter protein STY2637 97 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16760902 Common fliA flagellar biosynthesis sigma factor STY2164 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 16760506 Pathogen sseG putative pathogenicity island effector protein STY1715 1 None None None 16761289 Common dedD hypothetical protein STY2595 20 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 16760467 Common anmK anhydro-N-acetylmuramic acid kinase STY1676 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 16760347 Common - putative MFS-type transporter YdeE STY1544 48 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762379 Common sodA superoxide dismutase STY3816 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 16761915 Common uxaC glucuronate isomerase STY3308 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 16760917 Common fliJ flagellar biosynthesis chaperone STY2181 41 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 16762483 Common trmE tRNA modification GTPase TrmE STY3937 231 COG0486 ThdF, Predicted GTPase General function prediction only 16761885 Common trmB tRNA (guanine-N(7))-methyltransferase STY3264 177 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 16762041 Common - putative protease STY3457 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 16759790 Common potI putrescine transporter subunit: membrane component of ABC superfamily STY0913 178 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 16760765 Pathogen - hypothetical protein STY2022 1 None None None 16762794 Common mrcA peptidoglycan synthetase STY4303 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 16760389 Pathogen - hypothetical protein STY1594 1 None None None 16763170 Common psd phosphatidylserine decarboxylase STY4708 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 16760086 Common ndh NADH dehydrogenase STY1251 210 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 16760271 Common tehA potassium-tellurite ethidium and proflavin transporter STY1455 49 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 16762987 Common dmsC putative dimethyl sulfoxide reductase subunit C STY4508 18 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 16759185 Common dksA DnaK transcriptional regulator DksA STY0211 119 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 16763110 Common - hypothetical protein STY4648 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 16759075 Common - probable secreted protein STY0095 8 None None None 16759794 Common ulaA ascorbate-specific PTS system enzyme IIC STY0917 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 16763012 Pathogen pilM hypothetical protein STY4540 4 None None None 16762672 Common dppA periplasmic dipeptide transport protein precursor STY4168 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 16760814 Common kil Rac prophage killing protein STY2070 3 None None None 16759022 Pathogen - hypothetical protein STY0034 1 None None None 16762705 Common - predicted lipoproteinC STY4208 5 None None None 16761369 Common hemF coproporphyrinogen III oxidase STY2688 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 16762608 Common grxC glutaredoxin 3 STY4093 132 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 16762224 Common - hypothetical protein STY3650 18 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 16761862 Common speA arginine decarboxylase STY3240 116 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 16762505 Common ccmC2 heme exporter protein C2 STY3961 124 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 16762838 Common tuf elongation factor Tu STY4353 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 16759374 Common phoB DNA-binding response regulator in two-component regulatory system with PhoR (or CreC) STY0432 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16759252 Common - hypothetical protein STY0287 12 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 16759899 Pathogen - putative bacteriophage protein STY1038 1 None None None 16760128 Common purU formyltetrahydrofolate deformylase STY1294 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 16761780 Common ptsP fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain STY3144 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 16759084 Common apaG ApaG STY0104 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 16760428 Common - putative bacteriophage baseplate protein STY1634 18 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 16761237 Common - hypothetical protein STY2542 8 COG4575 ElaB, Uncharacterized conserved protein Function unknown 16762457 Common atpF F0F1 ATP synthase subunit B STY3909 128 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 161501921 Common - hypothetical protein STY3215 35 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 16762747 Common ugpE glycerol-3-phosphate transporter membrane protein STY4256 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 16759208 Common pyrH uridylate kinase STY0241 235 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 161501899 Common slt lytic murein transglycosylase STY4929 174 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16759140 Common hofB hypothetical protein STY0165 224 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 16760121 Common narK nitrite extrusion protein (nitrite facilitator) STY1287 79 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 16759289 Common safB periplasmic fimbrial chaperone protein STY0335 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16760335 Pathogen - putative ATP/GTP-binding protein STY1531 1 None None None 16761534 Common grpE heat shock protein GrpE STY2868 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 16761177 Common ccmF1 cytochrome c-type biogenesis protein F1 STY2475 157 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16760655 Common cspH putative cold shock protein STY1881 39 COG1278 CspC, Cold shock proteins Transcription 16761203 Common nrdA ribonucleotide-diphosphate reductase subunit alpha STY2506 208 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 16762625 Common - predicted glutathione S-transferase STY4112 76 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16760784 Common - putative bacteriophage protein STY2041 11 None None None 16762898 Common - hypothetical protein STY4413 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16760661 Pathogen - putative pertussis-like toxin subunit STY1890 2 None None None 16761347 Common ligA NAD-dependent DNA ligase LigA STY2663 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 16762444 Common rbsA D-ribose transporter ATP binding protein STY3896 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 16763190 Common yjfK hypothetical protein STY4729 9 None None None 16761319 Common - putative lipopolysaccharide modification acyltransferase STY2629 112 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 16759983 Common hpcD 5-carboxymethyl-2-hydroxymuconate delta-isomerase STY1138 33 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 16761771 Common ptr protease III precursor (pitrilysin) STY3133 141 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 16760054 Common flgF flagellar basal body rod protein FlgF STY1217 121 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 16761148 Common yeiO sugar efflux transporter STY2443 46 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762275 Common - putative phage tail protein STY3701 28 COG3499 COG3499, Phage protein U General function prediction only 16759545 Common fepA ferrienterobactin receptor precursor STY0628 110 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 16763177 Common amiB N-acetylmuramoyl-l-alanine amidase II STY4715 163 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 16759367 Common yaiA hypothetical protein STY0422 8 None None None 16760636 Common - putative inner membrane transport protein STY1863 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16760133 Common tdk thymidine kinase STY1301 94 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 16761192 Common alkB AlkB protein STY2490 58 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 16760760 Common - putative bacteriophage protein STY2017 8 None None None 16763199 Common yjfR putative L-ascorbate 6-phosphate lactonase STY4738 27 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 16761033 Common wzxC colanic acid exporter STY2314 105 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 16759147 Common aroP aromatic amino acid transporter STY0173 157 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 16761469 Common hmpA nitric oxide dioxygenase STY2803 129 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 16760593 Common xthA exonuclease III STY1812 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 16763041 Common - hypothetical protein STY4573 28 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 16762956 Common acs acetyl-CoA synthetase STY4473 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 16761955 Common - hypothetical protein STY3358 14 COG1359 COG1359, Uncharacterized conserved protein Function unknown 16762781 Common feoB ferrous iron transport protein B STY4290 178 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 16759588 Common pagP palmitoyl transferase for Lipid A STY0677 14 None None None 16760294 Common - putative lipoprotein STY1480 13 None None None 16762574 Common - hypothetical protein STY4059 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 16760666 Common - putative transcriptional regulator STY1898 53 COG2912 COG2912, Uncharacterized conserved protein Function unknown 16762829 Common slyX hypothetical protein STY4344 36 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 16761225 Common - bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase STY2529 245 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 16761213 Pathogen - hypothetical protein STY2516 1 None None None 16759011 Common - putative chitinase STY0018 38 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 16761567 Pathogen - hypothetical protein STY2905 1 None None None 16761029 Common rfbB dTDP-glucose 4,6 dehydratase STY2307 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 16762321 Common argC N-acetyl-gamma-glutamyl-phosphate reductase STY3752 216 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 16760059 Common flgK flagellar hook-associated protein FlgK STY1222 114 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 16761460 Common suhB inositol monophosphatase STY2792 215 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 16762337 Common metJ transcriptional repressor protein MetJ STY3770 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 16762727 Common - methyl-accepting chemotaxis citrate transducer STY4234 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 16762123 Common yhcP p-hydroxybenzoic acid efflux subunit AaeB STY3545 44 COG1289 COG1289, Predicted membrane protein Function unknown 16760974 Common pduD diol dehydratase medium subunit STY2246 13 None None None 16759391 Common tsx nucleoside-specific channel-forming protein tsx precursor STY0451 19 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 16759334 Pathogen - hypothetical protein STY0386 1 None None None 16763181 Common hflX putative GTPase HflX STY4719 231 COG2262 HflX, GTPases General function prediction only 16759203 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase STY0236 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 16761920 Common - possible ABC-transport protein, periplasmic-binding component STY3313 110 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 16762524 Common ilvB acetolactate synthase catalytic subunit STY3986 223 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 16762469 Common - hypothetical protein STY3923 91 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 16761950 Common parC DNA topoisomerase IV subunit A STY3351 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 16762652 Common - putative lipoprotein STY4142 6 None None None 16760952 Common erfK hypothetical protein STY2218 80 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 16759911 Common - putative bacteriophage protein STY1050 19 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 16762451 Common mioC flavodoxin STY3903 78 COG0716 FldA, Flavodoxins Energy production and conversion 16761797 Common yqeF acetyl-CoA acetyltransferase STY3164 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 16760219 Pathogen - hypothetical protein STY1396 1 None None None 16761245 Common nuoJ NADH dehydrogenase subunit J STY2550 139 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 16761951 Common - possible AraC-family transcriptional regulator STY3352 86 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 16759928 Common - putative bacteriophage protein STY1067 2 None None None 16761811 Common - hypothetical protein (assiciated with virulence) STY3183 22 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 16759819 Pathogen - hypothetical protein STY0945 2 None None None 16761230 Common pmrD polymyxin B resistance protein STY2534 4 None None None 16763365 Common deoD purine nucleoside phosphorylase STY4921 95 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 16760471 Common - putative HlyD-family protein STY1680 166 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16760046 Common mviN virulence factor MviN STY1209 190 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 16759804 Common - putative N-acetylmuramoyl-L-alanine amidase STY0927 106 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 16762092 Common gltB glutamate synthase subunit alpha STY3510 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 16762809 Common nirC nitrite transporter NirC STY4320 91 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 16763212 Common - hypothetical protein STY4751 51 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 16759631 Common ybfM putative outer membrane protein STY0725 14 None None None 16760941 Pathogen - hypothetical protein STY2207 1 None None None 16761058 Common yegB multidrug efflux system protein MdtE STY2342 192 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759547 Common ybdZ hypothetical protein STY0630 27 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 16761789 Common galR DNA-binding transcriptional repressor STY3155 127 COG1609 PurR, Transcriptional regulators Transcription 16763317 Common - hypothetical protein STY4865 9 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 16759113 Common fruR DNA-binding transcriptional regulator FruR STY0138 122 COG1609 PurR, Transcriptional regulators Transcription 16761929 Common - hypothetical protein STY3323 8 None None None 16760847 Common yebB hypothetical protein STY2105 8 None None None 16762837 Common fusA elongation factor G STY4352 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 16759850 Common cmk cytidylate kinase STY0980 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 16760961 Common cbiH precorrin-3B C17-methyltransferase STY2232 180 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 16761296 Common div predicted flagella assembly protein STY2602 10 None None None 16761805 Common stdC probable fimbrial chaperone protein STY3175 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16759349 Common prpE PrpE protein STY0403 217 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 16760959 Common cbiN cobalt transport protein CbiN STY2225 41 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 16762159 Common tatC TatABCE protein translocation system subunit STY3584 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 16759606 Common rlpB LPS-assembly lipoprotein RplB STY0698 25 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 16759567 Common ahpC alkyl hydroperoxide reductase subunit C STY0653 216 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16761585 Common - hypothetical protein STY2928 82 COG2128 COG2128, Uncharacterized conserved protein Function unknown 161501914 Common recQ ATP-dependent DNA helicase RecQ STY3601 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 16759156 Common - hypothetical protein STY0182 22 COG3112 COG3112, Uncharacterized protein conserved in bacteria Function unknown 16760363 Common dmsA1 putative dimethyl sulphoxide reductase subunit STY1565 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16761728 Common steC periplasmic fimbrial chaperone STY3087 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16762511 Common yidR putative ATP/GTP-binding protein STY3967 13 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 16760540 Common - hypothetical protein STY1756 6 None None None 16759960 Common - hypothetical protein STY1102 31 COG3785 COG3785, Uncharacterized conserved protein Function unknown 16760898 Common yecS putative ABC transporter membrane protein STY2160 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 16763234 Common ppa inorganic pyrophosphatase STY4773 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 16759317 Common proA gamma-glutamyl phosphate reductase STY0367 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 16762175 Common rhtC threonine efflux system STY3600 121 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 16759592 Common lipA lipoyl synthase STY0683 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 16760063 Common - hypothetical protein STY1226a 3 None None None 16761941 Common - possible membrane transport protein STY3340 97 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 16759802 Common - predicted lipoprotein STY0925 9 None None None 16762429 Common yihI hypothetical protein STY3878 19 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 16763037 Common - hypothetical protein STY4569 22 None None None 16761642 Pathogen - hypothetical protein STY2986a 1 None None None 16762475 Common pstB phosphate transporter subunit STY3929 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 16763053 Pathogen - hypothetical protein STY4586 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16761555 Common - putative DNA-invertase STY2889 135 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 16761971 Common glgS glycogen synthesis protein GlgS STY3376 5 None None None 16761793 Common ygeA putative racemase STY3159 74 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 16760619 Common - hypothetical protein STY1846 16 COG2261 COG2261, Predicted membrane protein Function unknown 16762229 Common ilvM acetolactate synthase 2 regulatory subunit STY3655 22 COG3978 COG3978, Acetolactate synthase (isozyme II), small (regulatory) subunit Function unknown 16759931 Common - putative bacteriophage protein STY1070 20 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 16761845 Common iciA chromosome replication initiation inhibitor protein STY3220 79 COG0583 LysR, Transcriptional regulator Transcription 16762751 Common ggt gamma-glutamyltranspeptidase periplasmic precursor STY4260 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 16759121 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase STY0146 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 16761026 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase STY2304 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 16759823 Common - putative pirin-related protein STY0949 147 COG1741 COG1741, Pirin-related protein General function prediction only 16762351 Common fpr ferredoxin-NADP reductase STY3786 114 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 16759346 Common prpB 2-methylisocitrate lyase STY0400 135 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 16759229 Common yaeP hypothetical protein STY0263 12 None None None 161501910 Common - hypothetical protein STY3933 116 COG0431 COG0431, Predicted flavoprotein General function prediction only 16762732 Common yhhF predicted methyltransferase STY4239 202 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 16763027 Common - hypothetical protein STY4558 21 None None None 16762861 Common rpmD 50S ribosomal protein L30 STY4376 154 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 16761158 Common yejE putative binding-protein-dependent transporter STY2454 218 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 16762722 Common - hypothetical protein STY4229 123 COG0628 PerM, Predicted permease General function prediction only 16761641 Common sitD Iron transport protein, inner membrane component STY2986 183 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 16759127 Common ftsA cell division protein FtsA STY0152 178 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 16759120 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase STY0145 220 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 16761151 Pathogen - hypothetical protein STY2446 1 None None None 16759728 Common moaC molybdenum cofactor biosynthesis protein C STY0838 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 16762364 Common - hypothetical protein STY3799 5 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 16760174 Common - translation initiation factor Sui1 STY1345 51 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 16761380 Common eutJ putative ethanolamine utilization protein EutJ STY2699 22 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 16760546 Common - hypothetical protein STY1762 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 16761354 Common pdxK pyridoxal kinase STY2672 84 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 16762012 Common tdcE probable formate acetyltransferase STY3423 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 16760885 Common yecA hypothetical protein STY2146 83 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 16760564 Pathogen - hypothetical protein STY1779a 1 None None None 16759141 Common ppdD putative major pilin subunit STY0166 35 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 16760421 Common - hypothetical protein STY1627 2 None None None 16761599 Common gshA glutamate--cysteine ligase STY2944 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 16761133 Common galS DNA-binding transcriptional repressor STY2425 128 COG1609 PurR, Transcriptional regulators Transcription 16760314 Common - putative secreted protein STY1502 8 None None None 16763306 Pathogen - hypothetical protein STY4854 1 None None None 16761913 Common uxuA mannonate dehydratase STY3306 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 16760220 Common - putative thiol peroxidase STY1397 58 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16762589 Pathogen - hypothetical protein STY4074 1 None None None 16762000 Common - hypothetical protein STY3408 18 None None None 16762862 Common rplO 50S ribosomal protein L15 STY4377 70 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 16759599 Common pbpA penicillin-binding protein 2 STY0691 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 16762151 Common pepQ proline dipeptidase STY3576 183 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 16759310 Common prfH peptide chain release factor-like protein STY0360 215 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 16759405 Common phnT probable ATP-binding component of 2-aminoethylphosphonate transporter STY0467 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 16762960 Common nrfC cytochrome c-type biogenesis protein STY4477 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16762717 Common - hypothetical protein STY4222 23 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 16762034 Common - hypothetical protein STY3450 68 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 16760777 Pathogen - putative bacteriophage protein STY2034 2 None None None 16762866 Common rpsK 30S ribosomal protein S11 STY4381 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 16761962 Common - hypothetical protein STY3365 21 COG5463 COG5463, Predicted integral membrane protein Function unknown 16762116 Common - possible transcriptional regulator STY3537 132 COG1802 GntR, Transcriptional regulators Transcription 16759416 Common - hypothetical protein STY0478 3 None None None 16762918 Common lexA LexA repressor STY4433 174 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 16760840 Common yebA hypothetical protein STY2098 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 16761017 Common rfbU putative glycosyltransferase STY2295 174 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16762009 Pathogen - hypothetical protein STY3417 4 None None None 16761590 Common nrdF ribonucleotide-diphosphate reductase subunit beta STY2933 140 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 16761337 Common yfeC hypothetical protein STY2652 6 None None None 16760928 Common yodD hypothetical protein STY2192 6 None None None 16760703 Common - hypothetical protein STY1943 35 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 16759778 Common - hypothetical protein STY0901 72 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 16761001 Pathogen hisL his operon leader peptide STY2279A 1 None None None 16759684 Common tolQ colicin uptake protein TolQ STY0791 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 16760808 Common - hypothetical protein STY2064 5 None None None 16759302 Common - probable secreted protein STY0352 4 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 16762162 Common ubiB putative ubiquinone biosynthesis protein UbiB STY3587 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 16762949 Common - putative xanthine/uracil permeases family protein STY4466 134 COG2252 COG2252, Permeases General function prediction only 16762078 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase STY3495 107 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 16761896 Pathogen - hypothetical protein STY3285 2 None None None 16760783 Common - putative bacteriophage protein STY2040 27 COG1783 XtmB, Phage terminase large subunit General function prediction only 16760557 Common pheS phenylalanyl-tRNA synthetase subunit alpha STY1773 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 16762046 Common - lipoprotein NlpI STY3462 65 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 16760534 Common - selenocysteine lyase STY1750 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 16761067 Pathogen - hypothetical protein STY2351 1 None None None 16759721 Common bioC predicted methyltransferase STY0829 170 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 16760502 Common ssaJ putative pathogenicity island lipoprotein STY1711 28 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 16758995 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I STY0002 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 16762941 Common - large repetitive protein STY4458 114 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 16762909 Common malF maltose transporter membrane protein STY4424 137 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 16759221 Common dnaE DNA polymerase III subunit alpha STY0254 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 16763123 Common tviB Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase STY4661 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 16761576 Common ygaE DNA-binding transcriptional regulator CsiR STY2914 117 COG1802 GntR, Transcriptional regulators Transcription 16762503 Common ccmA2 heme exporter protein A2 STY3959 134 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 16760103 Common - hypothetical protein STY1268 5 None None None 16760521 Common - putative transcriptional regulator STY1730 43 COG0789 SoxR, Predicted transcriptional regulators Transcription 16760095 Common - N-acetyl-D-glucosamine kinase STY1260 135 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 16760215 Pathogen - hypothetical protein STY1392 1 None None None 16761013 Common rfbP undecaprenyl-phosphate galactosephosphotransferase STY2291 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 16762282 Common purD phosphoribosylamine--glycine ligase STY3710 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 16762657 Common - putative acetyltransferase STY4151 45 None None None 16763165 Common frdA fumarate reductase flavoprotein subunit STY4703 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 16760203 Common tyrR DNA-binding transcriptional dual regulator, tyrosine-binding STY1378 173 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 16762200 Common yifK putative transport protein YifK STY3625 114 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 16762420 Common - hypothetical protein STY3865 6 None None None 16760994 Common phsC thiosulfate reductase cytochrome b subunit STY2269 16 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 161501943 Common fnr fumarate/nitrate reduction transcriptional regulator STY1404 159 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16762238 Common - hypothetical protein STY3664 6 None None None 16759605 Common holA DNA polymerase III subunit delta STY0697 66 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 16759453 Common hha hemolysin expression-modulating protein STY0516 12 None None None 16762139 Common accC acetyl-CoA carboxylase biotin carboxylase subunit STY3560 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 16763222 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein STY4761 126 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 16760434 Common - alternative bacteriophage tail fiber C-terminus STY1640 19 None None None 16760414 Common - hypothetical protein STY1620 10 None None None 16759834 Common serS seryl-tRNA synthetase STY0961 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 16761493 Common rnc ribonuclease III STY2827 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 16762187 Common dapF diaminopimelate epimerase STY3612 202 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 16759922 Common - putative bacteriophage protein STY1061 19 None None None 16759737 Common - putative inner membrane protein STY0851 130 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 16762554 Common mgtB Magnesium transport ATPase, P-type 2 STY4023 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 16760588 Common astE succinylglutamate desuccinylase STY1807 25 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 16761416 Common upp uracil phosphoribosyltransferase STY2739 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 16762660 Common - putative transcriptional regulator STY4154 7 COG2944 COG2944, Predicted transcriptional regulator Transcription 16759894 Common - putative damage-inducible protein STY1032 13 None None None 16761123 Common yohJ hypothetical protein STY2411 45 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 16760860 Common - hypothetical protein STY2120 21 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 16760205 Common tpx thiol peroxidase STY1381 110 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16762418 Common - hypothetical protein STY3863 6 None None None 16763009 Common - hypothetical protein STY4535 12 None None None 16760162 Common btuR cob(I)yrinic acid a,c-diamide adenosyltransferase STY1332 138 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 16763073 Common - probable major tail sheath protein STY4607 41 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 16759064 Common caiC putative crotonobetaine/carnitine-CoA ligase STY0081 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16761425 Common - hypothetical protein STY2749 8 COG3680 COG3680, Uncharacterized protein conserved in bacteria Function unknown 16762724 Common - hypothetical protein STY4231 10 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 16762383 Common rhaT L rhamnose-proton symporter STY3823 14 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 16762410 Common yihV putative sugar kinase STY3854 164 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16761122 Common - putative transcriptional regulator STY2410 178 COG0583 LysR, Transcriptional regulator Transcription 16760001 Common putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase STY1159 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 16763336 Common - putative GTP-binding protein YjiA STY4888 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 16759234 Common proS prolyl-tRNA synthetase STY0269 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16761515 Common yfiH hypothetical protein STY2850 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 16759668 Common - hypothetical protein STY0772 43 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 16760674 Common - putative sulfate transporter YchM STY1907 155 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 16761822 Common prfB peptide chain release factor 2 STY3197 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 16761883 Common - hypothetical protein STY3262 11 None None None 16763332 Common hsdR type I restriction enzyme EcoKI subunit R STY4884 104 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 16761712 Common - hypothetical protein STY3067 26 None None None 16759706 Common modA molybdate transporter periplasmic protein STY0814 159 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 16762050 Common rbfA ribosome-binding factor A STY3466 172 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 16760581 Common celC N,N'-diacetylchitobiose-specific PTS system transporter subunit IIA STY1799 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 16762291 Common nudC NADH pyrophosphatase STY3719 108 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 16761677 Pathogen invH cell adherance/invasion protein STY3023 1 None None None 16759571 Common - molybdopterin-containing oxidoreductase catalytic subunit STY0659 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16760620 Pathogen - hypothetical protein STY1847 1 None None None 16762843 Common rplC 50S ribosomal protein L3 STY4358 230 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 16760758 Common - putative bacteriophage protein STY2015 10 None None None 16761394 Common yffH hypothetical protein STY2714 110 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16759004 Common yaaI hypothetical protein STY0011 4 None None None 16763229 Common ytfM hypothetical protein STY4768 129 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 16759716 Common hutH histidine ammonia-lyase STY0824 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 16761088 Common thiD phosphomethylpyrimidine kinase STY2375 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 16761833 Common - hypothetical protein STY3208 2 None None None 16762261 Common - putative phage baseplate assembly protein STY3687 30 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 16761327 Common tnpA transposase for insertion sequence element IS200 STY2640 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762286 Common yjaH hypothetical protein STY3714 10 None None None 16760105 Common phoQ sensor protein PhoQ STY1270 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16761397 Common narQ nitrate/nitrite sensor protein NarQ STY2718 140 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 16762810 Common nirD nitrite reductase small subunit STY4321 45 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 16762767 Common glgP glycogen phosphorylase STY4276 147 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 16759953 Common - hypothetical protein STY1094 20 COG3070 TfoX, Regulator of competence-specific genes Transcription 16759746 Common glnQ glutamine ABC transporter ATP-binding protein STY0866 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 16759212 Common cdsA CDP-diglyceride synthase STY0245 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 16759526 Common gtrB bactoprenol glucosyl transferase STY0606 176 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16760824 Common - hypothetical protein STY2079 11 None None None 16760252 Common - ABC transporter ATP-binding subunit STY1436 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 16760500 Common - putative pathogenicity island protein STY1709 4 None None None 16761682 Pathogen - hypothetical protein STY3032 4 None None None 16762515 Common yidE hypothetical protein STY3971 58 COG2985 COG2985, Predicted permease General function prediction only 16759446 Common - conserved hypothetical lipoprotein STY0509 29 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 16761999 Common - hypothetical protein STY3407 9 None None None 16759469 Common aes acetyl esterase STY0534 107 COG0657 Aes, Esterase/lipase Lipid metabolism 16760402 Common - hypothetical protein STY1608 10 None None None 16761741 Common ygcZ probable glucarate transporter STY3100 205 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16761268 Common - putative sugar phosphotransferase component II B STY2573 31 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 16759949 Common - hypothetical protein STY1089 123 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 16761454 Common hscB co-chaperone HscB STY2786 56 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 16761549 Common - putative bacteriophage tail protein STY2883 28 COG3499 COG3499, Phage protein U General function prediction only 16762674 Common dppC dipeptide transporter STY4170 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16762773 Common malP maltodextrin phosphorylase STY4282 140 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 16761736 Common rumA 23S rRNA 5-methyluridine methyltransferase STY3095 203 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 16762391 Common - hypothetical protein STY3833 60 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 16759106 Common leuC isopropylmalate isomerase large subunit STY0130 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 16761981 Common - hypothetical protein STY3386 168 COG0344 COG0344, Predicted membrane protein Function unknown 16759480 Common - putative ABC transporter ATP-binding protein YbbL STY0548 249 COG4619 COG4619, ABC-type uncharacterized transport system, ATPase component General function prediction only 16759309 Common - hypothetical protein STY0359 119 COG1690 RtcB, Uncharacterized conserved protein Function unknown 16762325 Common yijO putative AraC-family transcriptional regulator STY3756 120 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 16762501 Common torD chaperone protein TorD STY3957 18 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 16762730 Common - hypothetical protein STY4237 8 None None None 16760719 Common manX PTS system, mannose-specific IIAB component STY1959 89 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 16762470 Common aroE shikimate 5-dehydrogenase STY3924 174 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 16762594 Common waaY lipopolysaccharide core biosynthesis protein STY4079 5 COG0661 AarF, Predicted unusual protein kinase General function prediction only 16763312 Common - hypothetical protein STY4860 35 COG3439 COG3439, Uncharacterized conserved protein Function unknown 16762774 Common malQ 4-alpha-glucanotransferase STY4283 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 16761051 Common udk uridine kinase STY2335 100 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 16761222 Common ais Ais protein STY2526 4 None None None 16762851 Common rpmC 50S ribosomal protein L29 STY4366 93 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 16760578 Common - hypothetical protein STY1796 58 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 16759661 Common - UDP-galactopyranose mutase STY0759 59 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 16762759 Common gntR gluconate utilization operon repressor STY4268 126 COG1609 PurR, Transcriptional regulators Transcription 16763020 Common pilU prepilin peptidase STY4549 5 None None None 16761218 Common - putative transcriptional regulator STY2522 117 COG1414 IclR, Transcriptional regulator Transcription 16761301 Common - putative lipoprotein STY2607 4 None None None 16762109 Common degS serine endoprotease STY3529 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 16762147 Common yhdV possible lipoprotein STY3572 7 None None None 16762137 Common - putative sulfite oxidase subunit YedZ STY3558 75 COG2717 COG2717, Predicted membrane protein Function unknown 16760904 Common fliD flagellar capping protein STY2168 95 COG1345 FliD, Flagellar capping protein Cell motility and secretion 16761672 Common spak secretory protein (associated with virulence) STY3018 5 None None None 16760320 Pathogen - hypothetical protein STY1509 1 None None None 16760607 Common - putative regulatory protein STY1829 95 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 16762059 Common rrmJ 23S rRNA methyltransferase J STY3475 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 16759578 Common citT citrate carrier STY0667 99 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 16762858 Common rplF 50S ribosomal protein L6 STY4373 225 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 16763363 Common deoA thymidine phosphorylase STY4919 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 16761606 Common ygaD competence damage-inducible protein A STY2951 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 16762342 Common ftsN essential cell division protein STY3777 21 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 16761803 Pathogen - hypothetical protein STY3173 3 None None None 16762768 Common glpD glycerol-3-phosphate dehydrogenase STY4277 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 16759695 Common - ABC transporter permease (FecCD_family) STY0802 188 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 16759069 Common fixB putative electron transfer flavoprotein FixB STY0086 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 16762439 Common - hypothetical 20.8 kDa protein in rbsr-rrsc intergenic region STY3888 128 COG2186 FadR, Transcriptional regulators Transcription 16760169 Common ribA GTP cyclohydrolase II STY1340 192 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 16762217 Common rep ATP-dependent DNA helicase Rep STY3642 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 16759900 Pathogen - putative lipoprotein STY1039 1 None None None 16763308 Common - hypothetical protein STY4856 136 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 16760600 Common sppA protease 4 STY1819 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16761526 Common rplS 50S ribosomal protein L19 STY2860 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 16763358 Common - hypothetical protein STY4914 39 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 16763385 Pathogen - putative secreted protein STY4946 1 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760380 Common - multidrug efflux system protein MdtI STY1584 95 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 16762314 Common trmA tRNA (uracil-5-)-methyltransferase STY3745 176 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 16759496 Common garR 2-hydroxy-3-oxopropionate reductase STY0567 182 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 16759731 Common - hypothetical protein STY0843 45 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 16760245 Common acpD azoreductase STY1427 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 16759993 Common scsC secreted protein, suppressor for copper-sensitivity C precursor STY1151 78 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 16763102 Common - hypothetical protein STY4639 5 None None None 16760005 Common - putative membrane transporter STY1164 27 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 16760026 Common mdoC glucans biosynthesis protein STY1186 25 None None None 16760035 Common - hypothetical protein STY1197 6 None None None 16760794 Common - putative bacteriophage protein STY2051 8 None None None 16760921 Common fliN flagellar motor switch protein FliN STY2185 123 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 16759700 Common galT galactose-1-phosphate uridylyltransferase STY0808 79 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 16762559 Common - hypothetical protein STY4039 3 None None None 16762100 Common nanA N-acetylneuraminate lyase STY3520 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 16763247 Common - hypothetical protein STY4786 15 None None None 16762882 Common yrdB hypothetical protein STY4397 11 None None None 16762552 Common yicL hypothetical protein STY4021 95 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 16761694 Common - hypothetical protein STY3047 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 16760772 Common - putative bacteriophage protein STY2029 12 None None None 16763048 Pathogen - hypothetical protein STY4580 4 None None None 16759259 Common - ClpB-like protein STY0294 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 16761705 Common cysC adenylylsulfate kinase STY3058 145 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 16761877 Common - hypothetical protein STY3255 74 COG1872 COG1872, Uncharacterized conserved protein Function unknown 16759037 Common rpsT 30S ribosomal protein S20 STY0052 203 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 16762400 Common - hypothetical protein STY3844 22 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 16759512 Common cysS cysteinyl-tRNA synthetase STY0585 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16762643 Common yiaJ putative transcriptional regulator STY4131 120 COG1414 IclR, Transcriptional regulator Transcription 16759359 Common - hypothetical protein STY0413 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 16763000 Common - DNA helicase STY4522 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 16762742 Common livG leucine/isoleucine/valine transporter ATP-binding subunit STY4251 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 16762634 Common sgbH 3-keto-L-gulonate-6-phosphate decarboxylase STY4121 54 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 16761340 Common xapR DNA-binding transcriptional activator STY2655 184 COG0583 LysR, Transcriptional regulator Transcription 16762201 Common rffM putative UDP-N-acetyl-D-mannosaminuronic acid transferase STY3626 108 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 16759266 Common - probable lipoprotein STY0303 30 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 16759356 Common - hypothetical protein STY0410 6 None None None 16759655 Common - hypothetical protein STY0753 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 16760187 Pathogen - hypothetical protein STY1359 1 None None None 16762446 Common trkD potassium transport protein Kup STY3898 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 16763341 Common dnaC DNA replication protein DnaC STY4896 41 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 16759265 Common - hypothetical protein STY0302 31 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 16760287 Common - hypothetical protein STY1473 6 None None None 16762562 Common - alpha-xylosidase YicI STY4044 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 16760073 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II STY1236 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16761573 Common gabD succinate-semialdehyde dehydrogenase I STY2911 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16761432 Pathogen sinI hypothetical protein STY2761 2 None None None 16761075 Pathogen - hypothetical protein STY2361 1 None None None 16760327 Common - putative regulatory protein STY1521 138 COG2186 FadR, Transcriptional regulators Transcription 16762639 Common yiaM 2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM STY4127 50 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 16759250 Common dnaQ DNA polymerase III subunit epsilon STY0285 184 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 16762539 Common - putative carbohydrate kinase STY4001 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16759874 Common xis excisionase STY1012 6 None None None 16762462 Common atpC F0F1 ATP synthase subunit epsilon STY3914 179 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 16759430 Common lon DNA-binding ATP-dependent protease La STY0492 216 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 16762789 Common hslO Hsp33-like chaperonin STY4298 140 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 16762857 Common rpsH 30S ribosomal protein S8 STY4372 242 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 16763062 Common - hypothetical protein STY4595 14 None None None 16759750 Common ybiF threonine and homoserine efflux system STY0871 69 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 16759376 Common brnQ branched chain amino acid transport system II carrier protein STY0435 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 16759757 Common ybiT ABC transporter ATP-binding protein STY0879 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 16759980 Common hpcR homoprotocatechuate degradative operon repressor STY1132 76 COG1846 MarR, Transcriptional regulators Transcription 16759180 Common staB putative chaperone protein EcpD STY0206 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16760391 Pathogen - hypothetical protein STY1596 1 None None None 16759049 Common oadA pyruvate carboxylase subunit B STY0064 174 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 16760117 Common - hypothetical protein STY1283 27 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 16762532 Common uhpC regulatory protein UhpC STY3994 129 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16759291 Pathogen safD putative fimbrial structural subunit STY0337 2 None None None 16760131 Common galU UTP--glucose-1-phosphate uridylyltransferase subunit GalU STY1298 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 16760409 Common - hypothetical protein STY1615 24 COG4373 COG4373, Mu-like prophage FluMu protein gp28 General function prediction only 16763203 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase STY4742 55 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 16762623 Common mtlD mannitol-1-phosphate 5-dehydrogenase STY4110 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 16760260 Common - putative glycolate oxidase STY1444 115 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 16761627 Common hycD formate hydrogenlyase subunit 4 STY2972 182 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 16762632 Common sgbE L-ribulose-5-phosphate 4-epimerase STY4119 118 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16760158 Common trpE anthranilate synthase component I STY1328 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 16763251 Common nrdG anaerobic ribonucleotide reductase-activating protein STY4790 65 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 16759502 Common allC allantoate amidohydrolase STY0575 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 16759647 Common kdpC potassium-transporting ATPase subunit C STY0745 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 16759852 Common ihfB integration host factor subunit beta STY0982 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 16762698 Common - hypothetical protein STY4199 3 None None None 16760514 Pathogen sseA putative pathogenicity island protein STY1723 1 None None None 16759047 Common citA sensor kinase cita STY0062 169 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 16762641 Common yiaL hypothetical protein STY4129 28 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 16759032 Common - possible sulfatase STY0046 10 None None None 161501933 Common manZ mannose-specific PTS system protein IID STY1961 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 16759485 Common ybbA putative ABC transporter ATP-binding protein YbbA STY0553 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 16759503 Common allD ureidoglycolate dehydrogenase STY0576 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 16761092 Common stcC putative outer membrane usher protein STY2379 32 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16761760 Common gcvA DNA-binding transcriptional activator GcvA STY3122 189 COG0583 LysR, Transcriptional regulator Transcription 16761917 Common gsp bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase STY3310 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 16760476 Common - putative TetR-family transcriptional regulator STY1685 74 COG1309 AcrR, Transcriptional regulator Transcription 16761080 Pathogen - hypothetical protein STY2366 3 None None None 16761994 Common ygjQ hypothetical protein STY3402 45 COG2949 SanA, Uncharacterized membrane protein Function unknown 16761410 Common - putative permease STY2731 50 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16759883 Common - putative DNA-binding protein STY1021 3 None None None 16762749 Common ugpQ cytoplasmic glycerophosphodiester phosphodiesterase STY4258 160 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 16759393 Common ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase STY0455 223 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 16762545 Common - putative PTS system protein STY4013 50 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 16760024 Common - hypothetical protein STY1184 117 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 16761208 Common glpQ glycerophosphodiester phosphodiesterase STY2511 115 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 16759782 Common grxA glutaredoxin 1 STY0905 44 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 16759557 Common entA 2,3-dihydroxybenzoate-2,3-dehydrogenase STY0642 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16761261 Common - hypothetical protein STY2566 23 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 16761687 Common - possible permease STY3038 76 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16762961 Common nrfD cytochrome c-type biogenesis protein STY4478 24 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 16762934 Pathogen - putative lipoprotein STY4449 2 None None None 16762307 Common tuf elongation factor Tu STY3739 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 16759786 Common - hypothetical protein STY0909 13 None None None 16759762 Common moeB molybdopterin biosynthesis protein MoeB STY0884 221 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 16759070 Common fixC putative oxidoreductase FixC STY0087 136 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 16759672 Common sdhD succinate dehydrogenase cytochrome b556 small membrane subunit STY0776 54 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 16761976 Common - hypothetical protein STY3381 59 COG3025 COG3025, Uncharacterized conserved protein Function unknown 16762617 Common lldP L-lactate permease STY4104 104 COG1620 LldP, L-lactate permease Energy production and conversion 16760356 Common - putative membrane transport protein STY1554 166 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16760591 Common astA arginine succinyltransferase STY1810 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 16761098 Common yehR putative lipoprotein STY2385 8 COG4808 COG4808, Uncharacterized protein conserved in bacteria Function unknown 16762831 Common yheO hypothetical protein STY4346 48 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 16759948 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase STY1088 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 16763253 Pathogen - hypothetical protein STY4792 1 None None None 16760237 Common - probable pyruvate-flavodoxin oxidoreductase STY1419 116 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 16761048 Common yegH hypothetical protein STY2332 219 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 16760869 Common cheW purine-binding chemotaxis protein STY2129 122 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 16761743 Common yqcB tRNA pseudouridine synthase C STY3103 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16760358 Common rspA starvation sensing protein RspA STY1556 107 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16760497 Common ssaV secretion system apparatus protein SsaV STY1706 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 16763303 Common - hypothetical protein STY4851 8 None None None 16759866 Common ycbL hypothetical protein STY0999 223 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 16760298 Common - hypothetical protein STY1484 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 16760837 Common hexR DNA-binding transcriptional regulator HexR STY2095 94 COG1737 RpiR, Transcriptional regulators Transcription 16761032 Common - putative glycosyltransferase STY2310 210 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16762714 Common - putative DNA-binding protein STY4219 49 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 16759633 Common citA citrate-proton symporter STY0727 130 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16760985 Common pduS putative ferredoxin STY2258 71 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 16760150 Common - hypothetical protein STY1320 47 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 16762896 Common - hypothetical protein STY4411 9 None None None 16760030 Common msyB hypothetical protein STY1190 7 None None None 16760819 Common lar restriction alleviation and modification protein STY20074a 2 None None None 16761998 Common - hypothetical protein STY3406 156 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 16763095 Pathogen - hypothetical protein STY4630 3 None None None 16759272 Common - hypothetical protein STY0311 2 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 16760146 Common ispZ intracellular septation protein A STY1316 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 16760706 Common minE cell division topological specificity factor MinE STY1946 82 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 16759244 Common yafD hypothetical protein STY0279 31 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 16760487 Common ribE riboflavin synthase subunit alpha STY1696 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 16760148 Common - hypothetical protein STY1318 23 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 16761562 Common - hypothetical protein STY2897 95 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 16759437 Common - hypothetical protein STY0499 111 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16762300 Common rpoB DNA-directed RNA polymerase subunit beta STY3732 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 16762582 Common rpmG 50S ribosomal protein L33 STY4067 137 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 16759271 Common - hypothetical protein STY0310 2 None None None 16760458 Common - electron transport complex protein RnfG STY1667 57 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 16761860 Common - hypothetical protein STY3237 113 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 16759040 Common ileS isoleucyl-tRNA synthetase STY0055 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16762274 Common - hypothetical protein STY3700 32 COG5283 COG5283, Phage-related tail protein Function unknown 16762088 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase STY3505 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 16759972 Common - hypothetical protein STY1124 3 None None None 16763281 Common - regulatory protein STY4819 129 COG1609 PurR, Transcriptional regulators Transcription 16762763 Common glgB glycogen branching enzyme STY4272 150 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 16759711 Common ybhC possible pectinesterase precursor STY0819 18 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 16762974 Common pmrA DNA-binding response regulator in two-component regulatory system with BasS STY4491 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16759058 Common dapB dihydrodipicolinate reductase STY0073 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 16759629 Common nagE N-acetyl glucosamine specific PTS system components IIABC STY0723 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 16761118 Common - glutathione-S-transferase-family protein STY2406 93 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16761375 Common eutC ethanolamine ammonia-lyase small subunit STY2694 53 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 16763143 Common yjdC putative transcriptional regulator STY4681 39 COG1309 AcrR, Transcriptional regulator Transcription 16760876 Common yecG universal stress protein UspC STY2136 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 16760302 Common narZ respiratory nitrate reductase 2 alpha chain STY1488 103 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 16761692 Common slyA putative regulatory protein STY3045 114 COG1846 MarR, Transcriptional regulators Transcription 16762650 Common xylB xylulose kinase STY4138 182 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16762360 Common - putative ABC transporter permease protein STY3795 118 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 16762887 Common aceA isocitrate lyase STY4402 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 16760338 Common - hypothetical protein STY1535 15 None None None 16759603 Common cobD threonine-phosphate decarboxylase STY0695 230 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 16759018 Common bcfE fimbrial subunit STY0030 15 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760851 Common aspS aspartyl-tRNA synthetase STY2109 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16759094 Common - putative IS element transposase STY0115 77 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 16761078 Pathogen - hypothetical protein STY2364 2 None None None 16762522 Common emrD multidrug resistance protein D STY3981 176 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762277 Common - putative positive regulator of late gene transcription STY3703 11 None None None 16760896 Common sdiA DNA-binding transcriptional activator STY2158 30 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 16759280 Common - hypothetical protein STY0320 6 COG5435 COG5435, Uncharacterized conserved protein Function unknown 16761139 Common - putative hydrolase STY2431 149 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 16763192 Common yjfM hypothetical protein STY4731 5 COG5463 COG5463, Predicted integral membrane protein Function unknown 16762783 Common - putative transcription accessory protein STY4292 213 COG2183 Tex, Transcriptional accessory protein Transcription 16763179 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase STY4717 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 16760572 Common - predicted hydrolase STY1789 172 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 16762827 Common yheV hypothetical protein STY4342 21 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 16759360 Common - possible efflux pump STY0414 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16761922 Common hypA hydrogenase nickel incorporation protein HybF STY3315 99 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 16760164 Common - predicted inner membrane peptidase STY1334 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16763155 Common yjeK hypothetical protein STY4693 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 16763379 Common creC sensory histidine kinase CreC STY4936 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16759561 Common ybdH putative oxidoreductase STY0646 65 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 16763043 Common - hypothetical protein STY4575 19 None None None 16759773 Common dacC D-alanyl-D-alanine carboxypeptidase fraction C STY0896 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 16759498 Common allB allantoinase STY0571 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 16759582 Common citE citrate lyase beta chain STY0671 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 16759315 Common phoE outer membrane phosphoporin protein E STY0365 25 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 16759425 Common yajG hypothetical protein STY0487 19 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 16761462 Common asrA anaerobic sulfite reductase subunit A STY2794 30 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 16761389 Common maeB malic enzyme STY2709 216 COG0281 SfcA, Malic enzyme Energy production and conversion 16760764 Pathogen - putative bacteriophage protein STY2021 1 None None None 16762991 Pathogen - hypothetical protein STY4512 6 None None None 16761767 Common - N-acetylmuramoyl-L-alanine amidase STY3129 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 16763051 Common - hypothetical protein STY4584 17 COG1475 Spo0J, Predicted transcriptional regulators Transcription 16760668 Common hemK N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase STY1900 213 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 16763220 Common ytfG hypothetical protein STY4759 90 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16759959 Common - hypothetical protein STY1101 131 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 16760374 Common - putative regulatory protein STY1576 165 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 16761613 Pathogen - hypothetical protein STY2958 1 None None None 16761448 Pathogen - hypothetical protein STY2780 2 None None None 16763320 Common iadA isoaspartyl dipeptidase STY4868 49 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 16760996 Common phsA thiosulfate reductase precursor STY2271 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16759339 Common - probable terminal oxidase subunit II STY0393 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 16762323 Common ppc phosphoenolpyruvate carboxylase STY3754 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 16761957 Common - esterase YqiA STY3360 47 COG3150 COG3150, Predicted esterase General function prediction only 16760566 Common - putative outer membrane protein STY1783 23 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 16763068 Common - putative phage tail protein STY4602 28 COG3499 COG3499, Phage protein U General function prediction only 16763183 Common hflC FtsH protease regulator HflC STY4721 149 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 16762576 Common pyrE orotate phosphoribosyltransferase STY4061 145 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 16761317 Common yfdC hypothetical protein STY2625 37 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 16760663 Pathogen - putative bacteriophage protein STY1893 1 None None None 16759696 Common - ABC transporter ATP-binding protein STY0803 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 16760460 Common nth endonuclease III STY1669 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 16761890 Common yqgA hypothetical protein STY3272 47 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 16761373 Common eutK ethanolamine utilization protein EutK STY2692 26 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 16759332 Common - probable lipoprotein STY0383 19 None None None 16761802 Pathogen - hypothetical protein STY3172 1 None None None 16761569 Common - hypothetical protein STY2907 13 None None None 16761419 Common ppk polyphosphate kinase STY2742 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 16762690 Common kdgK 2-dehydro-3-deoxygluconokinase STY4191 150 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16762358 Common - putative ABC transport protein, solute-binding component STY3793 51 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 16761724 Common eno phosphopyruvate hydratase STY3081 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 16761175 Common ccmH1 cytochrome c-type biogenesis protein H1 STY2473 87 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 16759468 Common hemH ferrochelatase STY0533 161 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 16760048 Common flgM anti-sigma28 factor FlgM STY1211 12 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 16760949 Pathogen - hypothetical protein STY2215 1 None None None 16759308 Common dinP DNA polymerase IV STY0358 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 16760257 Common - putative esterase STY1441 69 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 16761826 Common fldB flavodoxin FldB STY3201 67 COG0716 FldA, Flavodoxins Energy production and conversion 16759553 Common fepB iron-enterobactin transporter periplasmic binding protein STY0638 51 COG4592 FepB, ABC-type Fe2+-enterobactin transport system, periplasmic component Inorganic ion transport and metabolism 16762377 Common - hypothetical protein STY3814 8 None None None 16760638 Common - putative substrate-binding transport protein STY1865 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 16760631 Common - hypothetical protein STY1858 19 COG3443 COG3443, Predicted periplasmic or secreted protein General function prediction only 16762290 Common hemE uroporphyrinogen decarboxylase STY3718 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 16762891 Common yjbB hypothetical protein STY4406 84 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 161501901 Common fklB peptidyl-prolyl cis-trans isomerase STY4753 145 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 16760000 Common - putative secreted protein STY1158 35 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 16761360 Common cysW sulfate/thiosulfate transporter permease subunit STY2679 225 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 16760469 Common slyA transcriptional regulator SlyA STY1678 120 COG1846 MarR, Transcriptional regulators Transcription 16760342 Common - multiple drug resistance protein MarC STY1539 159 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 16759792 Common rumB 23S rRNA metyluridine methyltransferase STY0915 182 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 16761276 Common hisP histidine/lysine/arginine/ornithine transporter subunit STY2581 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 16760740 Common - putative secreted protein STY1983 8 None None None 16759753 Common ybiP hypothetical protein STY0875 38 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 16761734 Common - hypothetical protein STY3093 28 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 16762102 Common sspB ClpXP protease specificity-enhancing factor STY3522 64 COG2969 SspB, Stringent starvation protein B General function prediction only 16763241 Common - hypothetical protein STY4780 11 None None None 16761668 Common spaO surface presentation of antigens protein SpaO STY3014 8 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 16761996 Common - possible drug efflux protein STY3404 104 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 16759441 Common mdlA putative multidrug transporter membrane\ATP-binding components STY0503 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 16763112 Common yjhP hypothetical protein STY4650 40 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 16763172 Common orn oligoribonuclease STY4710 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 16761403 Common - hypothetical protein STY2724 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 16760233 Pathogen - hypothetical protein STY1413 2 None None None 16761015 Common rfbM2 mannose-1-phosphate guanylyltransferase STY2293 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 16761019 Common rfbX putative O-antigen transporter STY2297 9 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 16759735 Common - hypothetical protein STY0849 6 None None None 16760754 Pathogen - hypothetical protein STY2006 1 None None None 16762396 Common fdoG formate dehydrogenase-O, major subunit STY3839 186 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 161501923 Common - hypothetical protein STY2909 12 None None None 16759796 Common - probable sulfatase STY0919 55 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 16761773 Common ppdC hypothetical protein STY3135 7 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 16761661 Pathogen sipC pathogenicity island 1 effector protein STY3007 4 None None None 16762670 Common - putative lacI-family transcriptional regulator STY4164 123 COG1609 PurR, Transcriptional regulators Transcription 16762021 Common gatY tagatose-bisphosphate aldolase STY3435 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 16762605 Common - hypothetical protein STY4090 192 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 16763014 Common pilO putative pilus assembly protein STY4543 8 None None None 16760273 Common - putative lipoprotein STY1457 13 None None None 16762703 Common - hypothetical protein STY4206 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 16761629 Common hycB formate hydrogenlyase subunit 2 STY2974 141 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 16760368 Common - putative ABC transporter membrane protein STY1570 180 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 16762710 Common uspB universal stress protein UspB STY4213 12 None None None 16760585 Common nadE NAD synthetase STY1803 131 COG0171 NadE, NAD synthase Coenzyme metabolism 16759389 Common yajD hypothetical protein STY0449 26 None None None 16762222 Common ilvC ketol-acid reductoisomerase STY3648 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 16763236 Common mpl murein peptide ligase STY4775 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 16762761 Common gntU gluconate transporter, low affinity GNT 1 system STY4270 78 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16760426 Common - putative bacteriophage regulatory protein STY1632 42 COG3500 COG3500, Phage protein D General function prediction only 16762824 Common yheS putative ABC transporter ATP-binding protein STY4339 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 16761131 Common mglC beta-methylgalactoside transporter inner membrane component STY2421 128 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 16760115 Common chaA calcium/sodium:proton antiporter STY1281 54 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 16760612 Common - hypothetical protein STY1838 28 COG2707 COG2707, Predicted membrane protein Function unknown 16759168 Common yadG hypothetical ABC transporter ATP-binding protein STY0194 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 16760424 Common - hypothetical protein STY1630 9 COG3499 COG3499, Phage protein U General function prediction only 16759708 Common modC molybdate transporter ATP-binding protein STY0816 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 16759187 Common ligT 2'-5' RNA ligase STY0213 80 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 16761710 Common - hypothetical protein STY3065 44 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 16760815 Common - putative bacteriophage protein STY2071 2 None None None 16759319 Common stbE fimbrial chaperone protein STY0369 23 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16760196 Common pspA phage shock protein A STY1371 75 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 16761988 Common - hypothetical protein STY3393 56 COG1695 COG1695, Predicted transcriptional regulators Transcription 16760126 Common - putative secreted protein STY1292 110 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 16762547 Common - putative PTS system protein STY4015 37 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 161501952 Common hrpB ATP-dependent RNA helicase HrpB STY0214 132 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 16760316 Common - putative hydrolase STY1504 134 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 16761153 Common - hypothetical protein STY2449 15 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 16760281 Common pcgL D-alanyl-D-alanine dipeptidase STY1465 43 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 16760779 Common - putative bacteriophage protein STY2036 7 None None None 16762580 Common radC DNA repair protein RadC STY4065 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 16760745 Common - putative acetyltransferase STY1991 29 COG0456 RimI, Acetyltransferases General function prediction only 16759181 Common staA putative fimbrial protein STY0207 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16762145 Common yhdJ putative methyltransferase STY3566 140 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 16760185 Common sapC peptide transport system permease protein SapC STY1357 212 COG4171 SapC, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 16763218 Common ytfE cell morphogenesis/cell wall metabolism regulator STY4757 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 16762340 Common priA primosome assembly protein PriA STY3775 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 16760443 Common - hypothetical protein STY1650 97 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 16761851 Common pgk phosphoglycerate kinase STY3227 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 16759199 Common dgt deoxyguanosinetriphosphate triphosphohydrolase STY0230 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 16760555 Common ihfA integration host factor subunit alpha STY1771 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 16759143 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase STY0168 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 16763219 Common ytfF hypothetical protein STY4758 48 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 16762720 Common nikR nickel responsive regulator STY4227 59 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 16762864 Common rpmJ 50S ribosomal protein L36 STY4379 134 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 16759205 Common map methionine aminopeptidase STY0238 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 16761456 Common nifU scaffold protein STY2788 154 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 16762520 Common dsdC DNA-binding transcriptional dual regulator STY3979 174 COG0583 LysR, Transcriptional regulator Transcription 16759403 Common phnV probable membrane component of 2-aminoethylphosphonate transporter STY0465 204 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 16759077 Pathogen - probable secreted protein STY0097 2 None None None 16762007 Common - possible LysR-family transcriptional regulator STY3415 151 COG0583 LysR, Transcriptional regulator Transcription 16762036 Common - hypothetical protein STY3452 157 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 16762901 Common lysC aspartate kinase III STY4416 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 16759172 Common panD aspartate alpha-decarboxylase STY0198 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 16762868 Common rpoA DNA-directed RNA polymerase subunit alpha STY4383 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 16762715 Common - putative regulatory protein STY4220 185 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 16762010 Common - hypothetical protein STY3418 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 16759590 Common ccrB camphor resistance protein CrcB STY0679 183 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 16759896 Common - putative bacteriophage protein STY1034 11 None None None 16762938 Common - putative integral membrane protein STY4453 22 None None None 16760938 Common cspB cold shock protein STY2204 180 COG1278 CspC, Cold shock proteins Transcription 16759123 Common murG N-acetylglucosaminyl transferase STY0148 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 16763290 Common cI phage immunity repressor protein STY4829 4 None None None 16759558 Common ybdB hypothetical protein STY0643 71 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 16763087 Common - putative phage tail protein STY4622 25 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 16760699 Common - hypothetical protein STY1938 4 None None None 16759066 Common caiA crotonobetainyl-CoA dehydrogenase STY0083 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 16762943 Common - putative type-1 secretion protein STY4460 236 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 16761795 Common kduD 2-deoxy-D-gluconate 3-dehydrogenase STY3162 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16759812 Common - hypothetical protein STY0935 31 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 161501916 Common - hypothetical protein STY3469 179 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 16762339 Common rpmE 50S ribosomal protein L31 STY3774 196 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 16760713 Common - hypothetical protein STY1953 16 COG3140 COG3140, Uncharacterized protein conserved in bacteria Function unknown 16761588 Common nrdI ribonucleotide reductase stimulatory protein STY2931 38 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 16762207 Common rffH glucose-1-phosphate thymidylyltransferase STY3632 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 16762048 Common rpsO 30S ribosomal protein S15 STY3464 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 16760217 Pathogen - putative lipoprotein STY1394 1 None None None 16760792 Pathogen - hypothetical protein STY2049 1 None None None 16761003 Common hisD histidinol dehydrogenase STY2281 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 16761648 Common prgK pathogenicity 1 island effector protein STY2992 28 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 16759328 Pathogen - hypothetical protein STY0378 1 None None None 16762118 Common mdh malate dehydrogenase STY3539 178 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 16760523 Common ydhZ hypothetical protein STY1732 6 None None None 16759809 Common hcr HCP oxidoreductase, NADH-dependent STY0932 127 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 16760781 Common - hypothetical protein STY2038 18 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 16759179 Common staC predicted outer membrane usher protein STY0205 35 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16761095 Common yehE hypothetical protein STY2382 4 None None None 16763080 Common - putative phage baseplate assembly protein STY4615 30 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 16759354 Common sbmA transport protein STY0408 57 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 16759926 Common - putative secreted protein STY1065 2 None None None 16761339 Common gltX glutamyl-tRNA synthetase STY2654 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 16760508 Common sscB putative pathogenicity island protein STY1717 10 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 16761287 Common purF amidophosphoribosyltransferase STY2592 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 16761686 Common - possible LysR-family transcriptional regulator STY3037 141 COG0583 LysR, Transcriptional regulator Transcription 16759473 Common - hypothetical protein STY0541 103 COG2606 EbsC, Uncharacterized conserved protein Function unknown 16759451 Common - hypothetical protein STY0514 10 None None None 16759682 Common - hypothetical protein STY0789 15 COG3790 COG3790, Predicted membrane protein Function unknown 16762032 Common yraN hypothetical protein STY3448 128 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 16759817 Common clpS ATP-dependent Clp protease adaptor protein ClpS STY0942 121 COG2127 COG2127, Uncharacterized conserved protein Function unknown 16760726 Common cspC cold shock-like protein cspC STY1967 181 COG1278 CspC, Cold shock proteins Transcription 16762486 Common rpmH 50S ribosomal protein L34 STY3939A 109 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 16762655 Common yafP putative acetyltransferase STY4148 49 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 16763163 Common frdC fumarate reductase subunit C STY4701 23 COG3029 FrdC, Fumarate reductase subunit C Energy production and conversion 16761488 Common - putative ferredoxin STY2822 104 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 16759903 Common - putative bacteriophage protein STY1042 29 COG3179 COG3179, Predicted chitinase General function prediction only 16761264 Common - hypothetical protein STY2569 41 COG1288 COG1288, Predicted membrane protein Function unknown 16762791 Common yrfG putative hydrolase STY4300 41 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 16761799 Common - hypothetical protein STY3166 41 COG4125 COG4125, Predicted membrane protein Function unknown 16762126 Common - putative DNA-binding transcriptional regulator STY3547 182 COG0583 LysR, Transcriptional regulator Transcription 16761973 Common - hypothetical protein STY3378 40 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 16759522 Common fimY fimbriae Y protein STY0598 3 None None None 16759610 Common - 2-keto-3-deoxygluconate permease STY0702 27 None None None 16762459 Common atpA F0F1 ATP synthase subunit alpha STY3911 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 16759913 Common - putative bacteriophage protein STY1052 16 COG4834 COG4834, Uncharacterized protein conserved in bacteria Function unknown 16762734 Common ftsE cell division protein FtsE STY4241 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 16763372 Common - putative ABC transporter ATP-binding protein STY4928 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 16761247 Common nuoH NADH dehydrogenase subunit H STY2552 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 16762426 Common glnL nitrogen regulation protein NR(II) STY3875 220 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 16761632 Common hypB hydrogenase nickel incorporation protein HypB STY2977 117 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 161501924 Common - hypothetical protein STY2872 69 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 16762067 Common ispB octaprenyl diphosphate synthase STY3484 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 16759644 Common potE putrescine-ornithine antiporter STY0738 181 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16762431 Common - GTPase EngB STY3880 179 COG0218 COG0218, Predicted GTPase General function prediction only 161501928 Common ulaA ascorbate-specific PTS system enzyme IIC STY2572 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 16760791 Common - putative bacteriophage protein STY2048 10 None None None 16762696 Common yhjB hypothetical luxR-family transcriptional regulator STY4197 165 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16760431 Common - bacteriophage tail fiber protein STY1637 24 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 16762800 Common aroK shikimate kinase I STY4309 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 16760684 Common appC cytochrome bd-II oxidase subunit I (pseudogene) STY1919 164 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 16761165 Common rplY 50S ribosomal protein L25 STY2461 137 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 16760238 Common - hypothetical protein STY1420 10 COG3042 Hlx, Putative hemolysin General function prediction only 16762448 Common yieM hypothetical protein STY3900 29 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 16759848 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase STY0978 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 16761938 Common yghB DedA-family integral membrane protein STY3334 108 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 16761953 Common - DNA-binding response regulator in two-component regulatory system with QseC STY3354 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16760263 Common - ribulose-phosphate 3-epimerase STY1447 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 16760690 Common ldcA L,D-carboxypeptidase A STY1928 80 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 16761726 Common mazG nucleoside triphosphate pyrophosphohydrolase STY3083 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 16760672 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase STY1905 193 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 16759348 Common prpD 2-methylcitrate dehydratase STY0402 63 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 16760248 Common - putative cytochrome STY1431 80 COG3038 CybB, Cytochrome B561 Energy production and conversion 16759111 Common ilvI acetolactate synthase 3 catalytic subunit STY0135 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 16762289 Common nfi endonuclease V STY3717 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 16759656 Common - hypothetical protein STY0754 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 16761986 Common mug G/U mismatch-specific DNA glycosylase STY3391 29 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 16763035 Pathogen - hypothetical protein STY4566 4 None None None 16759192 Common fhuB iron-hydroxamate transporter permease subunit STY0221 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 16759152 Pathogen - probable secreted protein STY0178 2 None None None 16760130 Common - response regulator of RpoS STY1297 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 16759487 Common - outer membrane protein STY0556 10 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 16759158 Common ygbK hypothetical protein STY0184 62 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 16761330 Common - hypothetical protein STY2645 10 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 16761055 Common - multidrug efflux system subunit MdtA STY2339 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 16762568 Common spoT bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase STY4050 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 16759227 Common tilS tRNA(Ile)-lysidine synthetase STY0261 184 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 16761557 Common iroC putative ABC transporter protein STY2891 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 16763060 Pathogen - hypothetical protein STY4593 3 None None None 16760361 Common speG spermidine N1-acetyltransferase STY1561 102 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 16761967 Common dsbA disulfide isomerase STY3371 43 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 16762311 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase STY3742 204 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 16762385 Common rhaS L-rhamnose operon regulatory protein STY3825 145 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 16761943 Common - hypothetical protein STY3342 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 16760547 Common aroH phospho-2-dehydro-3-deoxyheptonate aldolase STY1763 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 16761782 Common mutH DNA mismatch repair protein STY3148 28 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 16761504 Common yfiD autonomous glycyl radical cofactor GrcA STY2839 52 COG3445 COG3445, Acid-induced glycyl radical enzyme General function prediction only 16760653 Pathogen - hypothetical protein STY1880 1 None None None 16760109 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase STY1274 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 16759800 Common artI arginine-binding periplasmic protein 1 precursor STY0923 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16760241 Common - hypothetical protein STY1423 16 None None None 16760950 Common - predicted multidrug efflux system STY2216 117 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 16762061 Common greA transcription elongation factor GreA STY3477 202 COG0782 GreA, Transcription elongation factor Transcription 16762157 Common rfaH transcriptional activator RfaH STY3582 38 COG0250 NusG, Transcription antiterminator Transcription 16760100 Common potB spermidine/putrescine ABC transporter membrane protein STY1265 219 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 16763029 Common - hypothetical protein STY4560 22 None None None 16759825 Common infA translation initiation factor IF-1 STY0951 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 16760734 Common proP putative solute/DNA competence effector STY1977 35 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 16762534 Common yicN hypothetical protein STY3996 8 None None None 16761066 Pathogen - hypothetical protein STY2350 1 None None None 16759534 Common - hypothetical protein STY0616 4 None None None 16762490 Common gyrB DNA gyrase subunit B STY3943 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 16761250 Common nuoE NADH dehydrogenase subunit E STY2555 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 16761847 Common - arginine exporter protein STY3222 84 COG1279 COG1279, Lysine efflux permease General function prediction only 16762465 Common glmS D-fructose-6-phosphate amidotransferase STY3917 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 16762030 Common - hypothetical protein STY3446 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 16763388 Common lasT putative RNA methyltransferase STY4949 149 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 16761211 Common glpB anaerobic glycerol-3-phosphate dehydrogenase subunit B STY2514 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 16762963 Common - formate-dependent nitrite reductase complex subunit NrfF STY4480 87 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 16763022 Pathogen 'pilV2 prepilin, alternative C-terminal region STY4551 1 None None None 16763100 Common - putative exonuclease STY4637 79 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 16761909 Common - hypothetical protein STY3300 33 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 16762596 Common waaK lipopolysaccharide 1,2-N-acetylglucosaminetransferase STY4081 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 161501912 Common glpX fructose 1,6-bisphosphatase II STY3785 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 16762981 Common melB melibiose:sodium symporter STY4498 76 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16761936 Pathogen - hypothetical protein STY3332a 4 None None None 16762853 Common rplN 50S ribosomal protein L14 STY4368 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 16760259 Common - hypothetical protein STY1443 112 COG2353 COG2353, Uncharacterized conserved protein Function unknown 16763105 Common cII phage regulatory protein STY4642 8 None None None 16759133 Common - putative aldo/keto reductase STY0158 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 16761472 Common cadA lysine decarboxylase STY2806 88 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 16762833 Common yheM hypothetical protein STY4348 33 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 16759991 Pathogen scsA membrane protein, suppressor for copper-sensitivity A STY1149 7 None None None 16762688 Common dctA C4-dicarboxylate transporter DctA STY4189 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 16761670 Pathogen spaM secretory protein (associated with virulence) STY3016 2 None None None 16760867 Common cheR chemotaxis regulator, protein-glutamate methyltransferase STY2127 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 16761540 Common smpB SsrA-binding protein STY2874 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 16759518 Common fimD outer membrane usher protein FimD precursor STY0593 32 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16761608 Common srlA PTS system, glucitol/sorbitol-specific IIBC component STY2953 22 COG3730 SrlA, Phosphotransferase system sorbitol-specific component IIC Carbohydrate transport and metabolism 16761220 Common - hypothetical protein STY2524 13 None None None 16762669 Pathogen - hypothetical protein STY4163 1 None None None 16761356 Common - glutamine amidotransferase STY2675 103 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 16760842 Common znuC high-affinity zinc transporter ATPase STY2100 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 16762025 Common gatA galactitol-specific PTS system component IIA STY3441 19 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 16762570 Common gmk guanylate kinase STY4052 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 16761934 Common exbD biopolymer transport protein ExbD STY3331 140 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 16762765 Common glgC glucose-1-phosphate adenylyltransferase STY4274 172 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 16763207 Pathogen - hypothetical protein STY4746 1 None None None 16762110 Common oadB oxaloacetate decarboxylase beta chain STY3531 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 16761423 Pathogen - hypothetical protein STY2746 3 None None None 16761984 Common dnaG DNA primase STY3389 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 16763356 Common osmY periplasmic protein STY4911 63 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 16759382 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase STY0442 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 16761524 Common - hypothetical protein STY2858 15 None None None 16763283 Common - protein kinase STY4822 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 16761859 Common tktA transketolase STY3236 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 16762128 Common - hypothetical protein STY3549 56 COG3164 COG3164, Predicted membrane protein Function unknown 16761477 Common - putative sensor kinase protein STY2811 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16762215 Common rhlB ATP-dependent RNA helicase RhlB STY3640 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 16759910 Common - putative bacteriophage protein STY1049 17 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 161501939 Common marA DNA-binding transcriptional activator MarA STY1541 124 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16760648 Common - putative secreted protein STY1875 3 None None None 16761216 Common - putative transport protein STY2520 128 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16761696 Common rpoS RNA polymerase sigma factor RpoS STY3049 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 16761809 Common - outer membrane protein (associated with virulence) STY3179 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16760550 Common - hypothetical protein STY1766 10 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16762819 Common yhfA hypothetical protein STY4332 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 16761762 Common - cysteine sulfinate desulfinase STY3124 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 16760070 Common fabD acyl carrier protein S-malonyltransferase STY1233 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 16759369 Common yaiE hypothetical protein STY0424 52 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 16762369 Common - hypothetical protein STY3806 82 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16762437 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A STY3886 135 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 16762556 Common fidL hypothetical protein STY4029 4 None None None 16759214 Common yaeT outer membrane protein assembly factor YaeT STY0247 162 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 16760641 Common - hypothetical protein STY1869 26 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 16760480 Common ydhD hypothetical protein STY1689 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 16760751 Pathogen - hypothetical protein STY2003 1 None None None 16761530 Common ffh signal recognition particle protein STY2864 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 16763075 Common - putative phage tail fibre protein STY4610 7 None None None 16759836 Common dmsB anaerobic dimethyl sulfoxide reductase chain B STY0963 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16761679 Common - hypothetical protein STY3027 45 COG0456 RimI, Acetyltransferases General function prediction only 16759232 Common cutF lipoprotein involved with copper homeostasis and adhesion STY0266 22 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 16760624 Common - leucine export protein LeuE STY1851 113 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 16763330 Common yjiW hypothetical protein STY4880 4 None None None 16761871 Common - hypothetical protein STY3249 131 COG1678 COG1678, Putative transcriptional regulator Transcription 16761750 Common xni exonuclease IX STY3111 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 16762872 Common mscL large-conductance mechanosensitive channel STY4387 134 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16761517 Common - predicted lipoprotein STY2852 126 COG4105 ComL, DNA uptake lipoprotein General function prediction only 16760125 Common narI respiratory nitrate reductase 1 gamma chain STY1291 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 16762090 Common arcB aerobic respiration control sensor protein ArcB STY3507 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16761551 Common - putative bacteriophage protein STY2885 8 None None None 16761898 Pathogen - hypothetical protein STY3288 6 None None None 16761881 Common ansB L-asparaginase II STY3259 140 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 16762263 Common - phage baseplate assembly protein STY3689 38 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 16762921 Common - putative stress-response protein STY4436 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 16762889 Common iclR acetate operon transcriptional repressor IclR STY4404 122 COG1414 IclR, Transcriptional regulator Transcription 16759006 Common dnaJ chaperone protein DnaJ STY0013 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 16760304 Common - putative regulatory protein STY1490 23 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 16760912 Common fliE flagellar hook-basal body protein FliE STY2176 71 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 16761129 Common insB insertion element IS1 protein InsB STY2419 21 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 16761828 Common - hypothetical protein STY3203 50 COG2938 COG2938, Uncharacterized conserved protein Function unknown 16759573 Common - molybdopterin-containing oxidoreductase membrane anchor subunit STY0661 15 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 16759278 Pathogen - hypothetical protein STY0318 1 None None None 16760622 Common - hypothetical protein STY1849 5 None None None 16760436 Common - alternative bacteriophage tail fiber C-terminus STY1642 16 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 16759744 Common ybiI hypothetical protein STY0862 26 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 16760144 Common tonB membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins STY1314 38 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 16760068 Common plsX fatty acid/phospholipid synthesis protein STY1231 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 16760305 Common smvA methyl viologen resistance protein SmvA STY1491 173 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759956 Common helD DNA helicase IV STY1097 227 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 16762184 Common yigB predicted hydrolase STY3609 67 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 16760542 Common - conserved hypothetical FAD-binding protein STY1758 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 16761399 Common yffB hypothetical protein STY2720 105 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 16762753 Common - hypothetical protein STY4262 19 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 161501905 Common nudE ADP-ribose diphosphatase NudE STY4302 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16759975 Common copS histidine kinase STY1127 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16761329 Common glk glucokinase STY2644 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 16759787 Common potF putrescine transporter subunit: periplasmic-binding component of ABC superfamily STY0910 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 16760387 Common - hypothetical protein STY1592 23 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 16762288 Common yjaG hypothetical protein STY3716 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 16759444 Common amtB ammonium transporter STY0507 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 16760724 Common rrmA 23S rRNA methyltransferase A STY1964 99 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 16760835 Common edd phosphogluconate dehydratase STY2093 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 16762903 Common - hypothetical protein STY4418 5 None None None 16761820 Common - isopentenyl-diphosphate delta-isomerase STY3195 54 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 16762416 Common - putative membrane permease STY3861 82 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16759471 Common ybaL putative cation:proton antiport protein STY0536 216 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 16761495 Common lepA GTP-binding protein LepA STY2829 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 16759482 Common ybbN thioredoxin-like protein STY0550 213 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 16762719 Common - hypothetical ABC transporter ATP-binding protein STY4224 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 16759565 Common ybdO putative lysR-family transcriptional regulator STY0651 128 COG0583 LysR, Transcriptional regulator Transcription 16762052 Common nusA transcription elongation factor NusA STY3468 216 COG0195 NusA, Transcription elongation factor Transcription 16759524 Pathogen fimW fimbriae w protein STY0600 2 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 16761835 Common gcvH glycine cleavage system protein H STY3210 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 16761308 Common aroC chorismate synthase STY2616 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 16760351 Common dcp dipeptidyl carboxypeptidase II STY1549 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 16761547 Common - putative bacteriophage late gene regulator STY2881 10 None None None 16760250 Common - hypothetical protein STY1434 25 COG5305 COG5305, Predicted membrane protein Function unknown 16760822 Common - putative integrase STY2077 25 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16763058 Pathogen - hypothetical protein STY4591 3 None None None 16759395 Common nusB transcription antitermination protein NusB STY0457 195 COG0781 NusB, Transcription termination factor Transcription 16762619 Common - putative lipoprotein STY4106 3 None None None 16763227 Common ytfL hypothetical protein STY4766 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 16761745 Common syd SecY interacting protein Syd STY3106 19 None None None 16762879 Common yrdD hypothetical protein STY4394 143 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 16761963 Common - hypothetical protein STY3366 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 16761333 Common - hypothetical protein STY2648 9 None None None 16761116 Common yohI tRNA-dihydrouridine synthase C STY2404 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 16761282 Common - putative amino acid permease STY2587 90 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 16759702 Common - hypothetical protein STY0810 11 COG4714 COG4714, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 16761263 Common pta phosphate acetyltransferase STY2568 171 COG0280 Pta, Phosphotransacetylase Energy production and conversion 16759296 Common tcfB putative fimbrial subunit STY0346 5 None None None 16760605 Common gapA glyceraldehyde-3-phosphate dehydrogenase STY1825 220 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 16761992 Common ygjO hypothetical protein STY3400 92 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 16761194 Common yojL thiamine biosynthesis lipoprotein ApbE STY2492 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 16759885 Common - putative replication protein STY1023 26 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 16763097 Pathogen - hypothetical protein STY4632 1 None None None 16759714 Common hutC histidine utilization repressor STY0822 125 COG2188 PhnF, Transcriptional regulators Transcription 16760947 Pathogen - hypothetical protein STY2213 4 None None None 16759868 Common ompF outer membrane protein F precursor STY1002 32 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 16760376 Common - putative membrane transport protein STY1579 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759929 Common - putative bacteriophage protein STY1068 12 None None None 16759620 Common - hypothetical protein STY0714 204 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 16759946 Common - putative lipoprotein STY1086 25 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 16762065 Common rpmA 50S ribosomal protein L27 STY3482 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 16761865 Common metK S-adenosylmethionine synthetase STY3243 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 16759072 Common yaaU putative metabolite transport protein STY0089 150 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16759775 Common ybjG undecaprenyl pyrophosphate phosphatase STY0898 62 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 16761435 Common - outer membrane protein assembly complex subunit YfgL STY2765 115 COG1520 COG1520, FOG: WD40-like repeat Function unknown 16763293 Common - Bacteriophage P4 DNA primase STY4832 54 COG3378 COG3378, Predicted ATPase General function prediction only 16760908 Common yedD hypothetical protein STY2172 7 None None None 16760829 Common exoX exodeoxyribonuclease X STY2084 154 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 16759555 Common entE enterobactin synthase subunit E STY0640 223 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 16761680 Common - serine/threonine-specific protein phosphatase 2 STY3030 71 None None None 16760022 Common - hypothetical protein STY1182 5 None None None 16759635 Common - tricarballylate dehydrogenase STY0729 52 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 16760453 Common - hypothetical protein STY1662 9 None None None 16760982 Common pduO hypothetical protein STY2255 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 16760455 Common - electron transport complex protein RnfB STY1664 120 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 16760398 Common - hypothetical protein STY1604 19 None None None 16761130 Common insA insertion element IS1 protein InsA STY2420 14 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760489 Common ssaU secretion system apparatus protein SsaU STY1698 129 COG4792 EscU, Type III secretory pathway, component EscU Intracellular trafficking and secretion 16762316 Common yijC DNA-binding transcriptional repressor FabR STY3747 42 COG1309 AcrR, Transcriptional regulator Transcription 16759242 Common yafC hypothetical transcriptional regulator STY0277 193 COG0583 LysR, Transcriptional regulator Transcription 16759428 Common clpP ATP-dependent Clp protease proteolytic subunit STY0490 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16759510 Common ybbF UDP-2,3-diacylglucosamine hydrolase STY0583 76 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 16763334 Common - hypothetical protein STY4886 25 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 16762712 Common - hypothetical protein STY4215 136 COG2081 COG2081, Predicted flavoproteins General function prediction only 16763136 Pathogen - hypothetical protein STY4674 1 None None None 16763305 Common - hypothetical protein STY4853 30 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 16761183 Common napC cytochrome c-type protein NapC STY2481 46 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 16759257 Pathogen - hypothetical protein STY0292 2 None None None 16760282 Common - putative regulatory protein STY1466 231 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 16761120 Common - putative gentisate 1,2-dioxygenase STY2408 30 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 16762084 Common ptsN sugar-specific enzyme IIA component of PTS STY3501 133 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 16762845 Common rplW 50S ribosomal protein L23 STY4360 135 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 16761978 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase STY3383 190 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 16759755 Common ybiR hypothetical protein STY0877 75 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 16759287 Common - hypothetical protein STY0328 4 None None None 16761560 Common iroN TonB-dependent outer membrane siderophore receptor protein STY2894 120 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 16759674 Common sdhB succinate dehydrogenase iron-sulfur subunit STY0778 202 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 16763285 Common - hypothetical protein STY4824 28 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 16760407 Common - hypothetical protein STY1613 10 None None None 16761451 Common yfhJ hypothetical protein STY2783 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 16762936 Common ssb single-strand DNA-binding protein STY4451 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 16761412 Common - hypothetical protein STY2735 125 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 16762086 Common ptsO phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) STY3503 124 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 16763269 Common - ornithine carbamoyltransferase subunit I STY4807 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 16763319 Common - putative DNA-binding transcriptional regulator STY4867 158 COG0583 LysR, Transcriptional regulator Transcription 16759970 Common sigE cell invasion protein STY1120 3 None None None 16762232 Common - probable bacteriophage integrase STY3658 162 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16759029 Common - putative secreted sulfatase STY0042 96 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 161501931 Common - UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase STY2527 204 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 16761879 Common - coproporphyrinogen III oxidase STY3257 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 16759035 Common - putative glycosyl hydrolase STY0049 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 16759030 Common - possible sulfatase regulatory protein STY0043 82 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 16762476 Common phoU transcriptional regulator PhoU STY3930 195 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 16760084 Common - beta-hexosaminidase STY1249 175 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 16761082 Pathogen - hypothetical protein STY2368 1 None None None 16762406 Common yihZ D-tyrosyl-tRNA deacylase STY3850 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 16762636 Common - insertion element IS1 protein InsA STY4124 14 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 16759974 Common pipD putative secreted peptidase STY1126 24 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 16763260 Common pyrI aspartate carbamoyltransferase regulatory subunit STY4799 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 16759008 Pathogen - hypothetical protein STY0015 2 None None None 16762740 Common livH branched-chain amino acid transporter permease subunit LivH STY4249 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 16761707 Common cysD sulfate adenylyltransferase subunit 2 STY3060 136 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 16760731 Common kdgR transcriptional regulator KdgR STY1972 123 COG1414 IclR, Transcriptional regulator Transcription 16759653 Common - putative hydrolase-oxidase STY0751 103 COG0327 COG0327, Uncharacterized conserved protein Function unknown 16763002 Pathogen - hypothetical protein STY4524 1 None None None 16761775 Common ppdB hypothetical protein STY3137 12 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 16763383 Common sthA putative fimbrial protein STY4944 19 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760289 Common - putative acetyltransferase STY1475 109 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 16762195 Common cyaA adenylate cyclase STY3620 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 16759108 Common leuA 2-isopropylmalate synthase STY0132 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 16762603 Common - predicted glycosyl transferase STY4088 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16759872 Common pncB nicotinate phosphoribosyltransferase STY1010 90 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 16759020 Common bcfG fimbrial chaperone STY0032 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16763205 Common sgaE L-ribulose-5-phosphate 4-epimerase STY4744 89 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16761145 Common fruA fructose-specific PTS system IIBC component STY2439 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 16761902 Pathogen - hypothetical protein STY3292 1 None None None 16760243 Common - putative secreted protein STY1425 28 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 16761430 Pathogen ratC hypothetical protein STY2756 3 None None None 16759051 Common citC citrate-sodium symporter STY0066 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 16759810 Common - hydroxylamine reductase STY0933 76 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 16760967 Common cobD cobalamin biosynthesis protein STY2239 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 16762803 Common dam DNA adenine methylase STY4312 98 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 16760029 Common - predicted lipoprotein STY1189 10 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 16763276 Common valS valyl-tRNA synthetase STY4814 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16762327 Common gldA glycerol dehydrogenase STY3759 115 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 16760512 Common sscA putative Type III secretion system chaperone protein STY1721 13 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 16763019 Common pilT hypothetical protein STY4548 27 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16760222 Common - hypothetical protein STY1399 34 COG3382 COG3382, Uncharacterized conserved protein Function unknown 16763145 Common cutA divalent-cation tolerance protein CutA STY4683 102 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 16760883 Common yecH hypothetical protein STY2144 13 None None None 16759261 Pathogen - hypothetical protein STY0296 3 None None None 16760235 Common - hypothetical protein STY1416 92 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 16762971 Common phnA hypothetical protein STY4488 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 16760400 Common - hypothetical protein STY1606 7 None None None 16759854 Common msbA lipid transporter ATP-binding/permease protein STY0985 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 16760474 Common - putative oxidoreductase STY1683 176 COG4989 COG4989, Predicted oxidoreductase General function prediction only 16761446 Common - putative lipoprotein STY2778 77 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 16759378 Common proY proline-specific permease ProY STY0438 157 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 16759509 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit STY0582 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 16762513 Common hslT heat shock protein IbpA STY3969 67 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 16763349 Common - hypothetical protein STY4904 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 16759937 Common - hypothetical protein STY1077 5 None None None 16760189 Common - hypothetical protein STY1361 3 None None None 16761722 Common - hypothetical protein STY3078 59 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 16762389 Common yiiL hypothetical protein STY3831 38 COG3254 COG3254, Uncharacterized conserved protein Function unknown 16762587 Common waaG lipopolysaccharide core biosynthesis protein STY4072 158 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16760384 Common pntA NAD(P) transhydrogenase subunit alpha STY1589 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 16763138 Common - hypothetical protein STY4676 12 None None None 16761044 Common wcaB putative colanic acid biosynthesis acetyltransferase WcaB STY2327 193 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 16761305 Common - hypothetical protein STY2611 18 None None None 16761278 Common hisQ histidine transport system permease protein STY2583 171 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 16763297 Common sefC outer membrane fimbrial usher protein STY4838 32 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16760199 Common pspD peripheral inner membrane phage-shock protein STY1374 7 None None None 16761266 Common - putative transketolase N-terminal section STY2571 221 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 16762185 Common xerC site-specific tyrosine recombinase XerC STY3610 228 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 16759952 Common sulA SOS cell division inhibitor STY1092 10 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 16760113 Common icdA isocitrate dehydrogenase STY1278 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 16761969 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase STY3373 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 16761350 Common cysK cysteine synthase A STY2666 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 16761923 Common hybE hydrogenase 2-specific chaperone STY3316 20 None None None 16761441 Common ndk nucleoside diphosphate kinase STY2771 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 16760240 Common ldhA D-lactate dehydrogenase STY1422 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 16760529 Common - putative amino acid permease STY1743 120 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16760433 Common - putative bacteriophage tail fiber assembly protein STY1639 11 None None None 16762225 Common - hypothetical protein STY3651 29 COG4679 COG4679, Phage-related protein Function unknown 16763381 Common sthD putative fimbrial subunit STY4940 8 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16761979 Common uppP undecaprenyl pyrophosphate phosphatase STY3384 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 16760946 Pathogen - hypothetical protein STY2212 1 None None None 16763327 Common - hypothetical protein STY4875 27 COG5464 COG5464, Uncharacterized conserved protein Function unknown 16760537 Common - cysteine desulfurase activator complex subunit SufB STY1753 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 16761490 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ STY2824 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 16760265 Common - hypothetical protein STY1449 38 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 16762560 Pathogen - hypothetical protein STY4041 1 None None None 16763099 Common - DNA adenine methylase STY4636 99 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 16762648 Common xylR xylose operon regulatory protein STY4136 116 COG1609 PurR, Transcriptional regulators Transcription 16759052 Common citC2 [citrate (PRO-3S)-lyase] ligase STY0067 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 16763003 Pathogen - hypothetical protein STY4525 7 None None None 16759054 Common citE2 citrate lyase beta chain STY0069 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 16761205 Common yfaE 2Fe-2S ferredoxin YfaE STY2508 52 COG0633 Fdx, Ferredoxin Energy production and conversion 16761053 Common alkA 3-methyl-adenine DNA glycosylase II STY2337 86 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 16760843 Common znuB high-affinity zinc transporter membrane component STY2101 174 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 16761094 Common stcA putative fimbrial subunit protein STY2381 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16759515 Common folD bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase STY0588 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 16759034 Common nhaR transcriptional activator NhaR STY0048 85 COG0583 LysR, Transcriptional regulator Transcription 16760042 Common - multidrug resistance protein MdtH STY1204 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16760878 Common otsB trehalose-6-phosphate phosphatase STY2138 89 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 16762171 Common yigM hypothetical protein STY3596 57 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 16762834 Common yheL hypothetical protein STY4349 24 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 16759433 Common ybaV hypothetical protein STY0495 78 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 16760413 Common - hypothetical protein STY1619 12 None None None 16762565 Common gltS glutamate permease STY4047 53 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 16759002 Common yaaH hypothetical protein STY0009 53 COG1584 COG1584, Predicted membrane protein Function unknown 16760405 Common - putative lipoprotein STY1611 4 None None None 16760979 Common pduK putative propanediol utilization protein PduK STY2251 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 16761471 Common cadB predicted lysine/cadaverine transporter STY2805 183 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16761715 Common - hypothetical protein STY3070 18 None None None 16762951 Common - lysR family regulatory protein STY4468 192 COG0583 LysR, Transcriptional regulator Transcription 16762784 Common greB transcription elongation factor GreB STY4293 201 COG0782 GreA, Transcription elongation factor Transcription 16760247 Common - hypothetical protein STY1429 10 COG1434 COG1434, Uncharacterized conserved protein Function unknown 16760871 Common motB flagellar motor protein MotB STY2131 115 COG1360 MotB, Flagellar motor protein Cell motility and secretion 16762638 Common yiaN hypothetical protein STY4126 115 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 16762614 Common yibK putative tRNA/rRNA methyltransferase YibK STY4101 162 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 16759263 Pathogen - hypothetical protein STY0300 3 None None None 16760614 Common - hypothetical protein STY1840 81 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 16760010 Common - putative sialic acid transporter STY1169 214 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762592 Common waaI lipopolysaccharide 1,3-galactosyltransferase STY4077 32 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 16761345 Common yfeH hypothetical protein STY2661 55 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 16761581 Common stpA DNA binding protein, nucleoid-associated STY2920 31 COG2916 Hns, DNA-binding protein H-NS General function prediction only 16760499 Common ssaL putative secretion system protein STY1708 5 None None None 16761022 Common rfbH putative dehydratase RfbH STY2300 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 16762610 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase STY4095 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 16762519 Common dsdX DsdX permease STY3978 80 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16759042 Common fkpB probable FkbB-type 16 kD peptidyl-prolyl cis-trans isomerase STY0057 99 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 16762686 Common yhjM endo-1,4-D-glucanase STY4183 31 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 16761776 Common ppdA hypothetical protein STY3138 10 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 16760229 Common - hypothetical protein STY1406 79 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 16759164 Common yacK multicopper oxidase STY0190 124 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 16763131 Pathogen - hypothetical protein STY4669 4 None None None 16760747 Pathogen - hypothetical protein STY1994 1 None None None 16760488 Common ydhE multidrug efflux protein STY1697 178 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 16763045 Common - hypothetical protein STY4577 22 None None None 16761162 Common bcr bicyclomycin/multidrug efflux system STY2458 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16763206 Common yjfY hypothetical protein STY4745 8 None None None 16761594 Common emrR transcriptional repressor MprA STY2939 84 COG1846 MarR, Transcriptional regulators Transcription 16759174 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase STY0200 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 16761137 Common - putative DNA-binding protein STY2429 12 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 16761144 Common nfo endonuclease IV STY2438 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 16760170 Common pgpB phosphatidylglycerophosphatase B STY1341 26 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 16759275 Common - probable secreted protein STY0314 2 None None None 16759855 Common lpxK tetraacyldisaccharide 4'-kinase STY0986 120 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 16762654 Common glyS glycyl-tRNA synthetase subunit beta STY4144 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 16761169 Common yejM putative sulphatase STY2466 40 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 16763280 Common - putative inner membrane protein STY4818 110 COG0795 COG0795, Predicted permeases General function prediction only 16762930 Common aphA acid phosphatase/phosphotransferase STY4445 12 COG3700 AphA, Acid phosphatase (class B) General function prediction only 16761481 Common yfhB hypothetical protein STY2815 13 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 16761310 Common - hypothetical protein STY2618 69 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 16759138 Common guaC guanosine 5'-monophosphate oxidoreductase STY0163 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 16763266 Common - carbamate kinase STY4804 69 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 16763264 Common - hypothetical protein STY4802 39 COG1288 COG1288, Predicted membrane protein Function unknown 16759284 Common - Rhs-family protein STY0324 75 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 16759484 Common tesA multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 STY0552 99 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 16762071 Common - possible anti-sigma factor antagonist STY3488 18 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 16762964 Common nrfG formate-dependent nitrite reductase complex subunit NrfG STY4481 31 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16761683 Common mutS DNA mismatch repair protein STY3033 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 16759637 Common fur ferric uptake regulator STY0731 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 16760396 Common gam bacteriophage host-nuclease inhibitor protein STY1601 8 COG4396 COG4396, Mu-like prophage host-nuclease inhibitor protein Gam General function prediction only 16761083 Common fbaB fructose-bisphosphate aldolase STY2370 69 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 16762368 Common - hypothetical protein STY3805 22 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16761321 Common pgtA phosphoglycerate transport system transcriptional regulatory protein PgtA STY2633 192 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 16759999 Common - putative transcriptional regulator STY1157 104 COG1309 AcrR, Transcriptional regulator Transcription 16762083 Common - putative sigma(54) modulation protein STY3500 127 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 16763109 Pathogen - hypothetical protein STY4647 1 None None None 16760352 Common - L-allo-threonine dehydrogenase, NAD(P)-binding STY1550 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 16759500 Common glxK glycerate kinase II STY0573 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 16762196 Common hemC porphobilinogen deaminase STY3621 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 16762386 Common rhaB rhamnulokinase STY3826 56 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16760457 Common rnfD electron transport complex protein RnfD STY1666 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 16760166 Common topA DNA topoisomerase I STY1336 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 16759231 Common yaeJ hypothetical protein STY0265 125 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 16759677 Common sucC succinyl-CoA synthetase subunit beta STY0781 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 16760472 Common - hypothetical protein STY1681 41 COG1289 COG1289, Predicted membrane protein Function unknown 16760866 Common cheB chemotaxis-specific methylesterase STY2126 211 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 16762744 Pathogen - hypothetical protein STY4253 1 None None None 16761717 Common sopD possible secreted protein STY3073 3 None None None 161501936 Common - putative oxidoreductase STY1660 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 16761866 Common galP galactose-proton symport (galactose transporter) STY3244 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16761721 Common - putative 6-pyruvoyl tetrahydrobiopterin synthase STY3077 131 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 16761499 Common rpoE RNA polymerase sigma factor RpoE STY2833 175 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 16760560 Common rpmI 50S ribosomal protein L35 STY1776 24 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 16759703 Common modF putative molybdenum transport ATP-binding protein ModF STY0811 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 16761614 Common srlR DNA-bindng transcriptional repressor STY2959 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16762846 Common rplB 50S ribosomal protein L2 STY4361 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 16760156 Common trpC bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase STY1326 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 16761186 Common napG quinol dehydrogenase periplasmic component STY2484 59 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16760090 Common - hypothetical protein STY1255 85 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 16762443 Common rbsC ribose ABC transporter permease protein STY3895 128 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 16763277 Common holC DNA polymerase III subunit chi STY4815 48 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 16761113 Common yohF acetoin dehydrogenase STY2401 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16759623 Common ubiF 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase STY0717 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 16760153 Common - hypothetical protein STY1323 12 None None None 16763092 Common - probable terminase subunit STY4627 24 COG5484 COG5484, Uncharacterized conserved protein Function unknown 16760490 Common ssaT putative type III secretion protein STY1699 106 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 16760853 Common yecE hypothetical protein STY2111 78 COG1801 COG1801, Uncharacterized conserved protein Function unknown 16762939 Common - putative type-I secretion protein STY4456 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16759249 Common rnhA ribonuclease H STY0284 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 16762213 Common rho transcription termination factor Rho STY3638 201 COG1158 Rho, Transcription termination factor Transcription 16762305 Common nusG transcription antitermination protein NusG STY3737 215 COG0250 NusG, Transcription antiterminator Transcription 16762817 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein STY4328 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 16760141 Common - dsDNA-mimic protein STY1311 18 COG3099 COG3099, Uncharacterized protein conserved in bacteria Function unknown 16763292 Common - hypothetical P4 phage protein STY4831 4 None None None 16759562 Common - putative aminotransferase STY0647 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 16760107 Common purB adenylosuccinate lyase STY1272 228 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 16760483 Common purR DNA-binding transcriptional repressor PurR STY1692 128 COG1609 PurR, Transcriptional regulators Transcription 16763015 Pathogen pilP pilus assembly protein STY4544 4 None None None 16761036 Common manC mannose-1-phosphate guanylyltransferase STY2317 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 16761293 Common truA tRNA pseudouridine synthase A STY2599 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 16760753 Common - hypothetical protein STY2005 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 16761512 Common kgtP alpha-ketoglutarate transporter STY2847 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16761486 Common - putative transmembrane transport protein STY2820 108 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 16761474 Common glnB nitrogen regulatory protein p-II STY2808 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 16763153 Common yjeI hypothetical protein STY4691 16 None None None 16760255 Common - hypothetical protein STY1439 55 COG3326 COG3326, Predicted membrane protein Function unknown 161501903 Common aidB isovaleryl CoA dehydrogenase STY4733 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 16760584 Common osmE DNA-binding transcriptional activator STY1802 11 None None None 16763008 Common - hypothetical protein STY4534 21 None None None 16761459 Common - putative RNA methyltransferase STY2791 157 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 16760231 Common zntB zinc transporter STY1409 95 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 16762604 Common - hypothetical protein STY4089 66 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 16759449 Common rpmE2 50S ribosomal protein L31 type B STY0512 102 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 16759256 Common - hypothetical protein STY0291 23 COG4455 ImpE, Protein of avirulence locus involved in temperature-dependent protein secretion General function prediction only 16759961 Common - hypothetical protein STY1103 141 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 16761103 Common yehV putative transcriptional regulator STY2390 30 COG0789 SoxR, Predicted transcriptional regulators Transcription 16762318 Common oxyR DNA-binding transcriptional regulator OxyR STY3749 192 COG0583 LysR, Transcriptional regulator Transcription 16760644 Pathogen - hypothetical protein STY1873 1 None None None 16761989 Common cheM methyl-accepting chemotaxis protein II STY3394 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 16763070 Common - hypothetical protein STY4604 8 None None None 16761101 Common yehT putative two-component response-regulatory protein YehT STY2388 213 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 16763232 Common - putative sugar transporter STY4771 147 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16762375 Common cpxR DNA-binding response regulator in two-component regulatory system with CpxA STY3812 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16760926 Common rcsA colanic acid capsullar biosynthesis activation protein A STY2190 11 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16760549 Common - hypothetical protein STY1765 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 16759276 Pathogen - probable secreted protein STY0316 1 COG4893 COG4893, Uncharacterized protein conserved in bacteria Function unknown 16760438 Common - putative amino acid permease STY1645 141 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16761546 Pathogen - hypothetical protein STY2880 1 None None None 16759216 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase STY0249 183 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 16763370 Common radA DNA repair protein RadA STY4926 215 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 16760178 Common rnb exoribonuclease II STY1350 191 COG4776 Rnb, Exoribonuclease II Transcription 16760317 Common glgX putative glycogen debranching protein STY1505 162 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 161501950 Common - nucleotide-binding protein STY0474 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 16762798 Common yrfA hypothetical protein STY4307 6 None None None 16761825 Common xerD site-specific tyrosine recombinase XerD STY3200 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16760307 Common sfcA NAD-linked malic enzyme; malate oxidoreductase STY1494 201 COG0281 SfcA, Malic enzyme Energy production and conversion 16760834 Common purT phosphoribosylglycinamide formyltransferase 2 STY2089 194 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 16762247 Common - hypothetical protein STY3673 5 None None None 16760642 Pathogen - hypothetical protein STY1870 1 None None None 16761128 Common - putative oxidoreductase STY2416 204 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 161501907 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase STY4064 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 16759440 Common ybaO hypothetical transcriptional regulator STY0502 149 COG1522 Lrp, Transcriptional regulators Transcription 16762415 Common yihP putative membrane permease STY3860 77 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16763160 Common sugE quaternary ammonium compound-resistance protein SugE STY4698 142 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 16762394 Common - putative lipoprotein STY3837 5 None None None 16761675 Common invG secretory protein (associated with virulence) STY3021 132 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 16762754 Common - hypothetical protein STY4263 12 COG5426 COG5426, Uncharacterized membrane protein Function unknown 16762219 Common - probable uridine phosphorylase STY3644 99 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 16759713 Common hutG formimidoylglutamase STY0821 119 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 16759575 Common ybdR hypothetical zinc-dependant alcohol dehydrogenase STY0663 207 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 16759240 Common yaeD D,D-heptose 1,7-bisphosphate phosphatase STY0275 133 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 16761769 Common RecD exonuclease V subunit alpha STY3131 142 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 16760340 Common - putative regulatory protein STY1537 188 COG0583 LysR, Transcriptional regulator Transcription 16759742 Common ybiJ hypothetical protein STY0860 11 None None None 16762878 Common smg hypothetical protein STY4393 40 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 16760627 Pathogen - hypothetical protein STY1854 3 None None None 16763244 Common - hypothetical protein STY4783 11 None None None 16762692 Common - hypothetical protein STY4193 35 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 16760962 Common cbiG cobalamin biosynthesis protein CbiG STY2233 93 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 16761753 Common fucP L-fucose transporter STY3115 49 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 16760894 Pathogen - hypothetical protein STY2156 1 None None None 16761431 Common ratA hypothetical protein STY2760 9 None None None 16759886 Common - putative DNA-binding protein STY1024 3 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16762776 Common - predicted gluconate transport-associated protein STY4285 69 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 16763056 Pathogen - hypothetical protein STY4589 3 None None None 16763249 Common relB bifunctional antitoxin/transcriptional repressor RelB STY4788 13 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 16761402 Common - hypothetical protein STY2723 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 16763352 Common holD DNA polymerase III subunit psi STY4907 19 COG3050 HolD, DNA polymerase III, psi subunit DNA replication, recombination, and repair 16762258 Common - putative regulatory protein STY3684 5 None None None 16762538 Common - putative PTS system IIC component STY4000 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 16760321 Common - putative isomerase STY1513 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 16759385 Common secD preprotein translocase subunit SecD STY0445 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 16760788 Pathogen - putative bacteriophage protein STY2045 1 None None None 16760192 Pathogen - hypothetical protein STY1367 1 None None None 16761188 Common yojF assembly protein for periplasmic nitrate reductase STY2486 17 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 16762885 Common metA homoserine O-succinyltransferase STY4400 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 16762433 Common yihG putative acyltransferase STY3882 31 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 16759898 Common - putative prophage antitermination protein STY1036 6 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 16760168 Common acnA aconitate hydratase STY1339 222 COG1048 AcnA, Aconitase A Energy production and conversion 16760530 Common pykF pyruvate kinase STY1744 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 16759423 Common cyoA cytochrome o ubiquinol oxidase subunit II STY0485 140 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 16763185 Common purA adenylosuccinate synthetase STY4723 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 16761816 Pathogen - hypothetical protein STY3191 1 None None None 16759828 Common cydD cysteine/glutathione ABC transporter membrane/ATP-binding component STY0955 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 16763023 Common rci shufflon-specific DNA recombinase STY4552 98 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 16762055 Common secG preprotein translocase subunit SecG STY3471 126 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 16760015 Common - hypothetical protein STY1175 15 None None None 16759749 Common dps DNA starvation/stationary phase protection protein Dps STY0870 118 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 16763122 Common tviC Vi polysaccharide biosynthesis protein, epimerase STY4660 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16759763 Common moeA molybdopterin biosynthesis protein MoeA STY0885 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 16759691 Common pnuC pnuC protein STY0798 61 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 16760571 Common - hypothetical protein STY1788 13 None None None 16760697 Common dsbB disulfide bond formation protein B STY1936 55 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 16760039 Common pyrC dihydroorotase STY1201 88 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 16760074 Common pabC 4-amino-4-deoxychorismate lyase STY1237 119 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 16759551 Common fepD iron-enterobactin transporter membrane protein STY0636 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 16763106 Pathogen apl phage regulatory protein STY4643 1 None None None 16761450 Common yfhI aminopeptidase B STY2782 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 16761601 Common - predicted hydrolase STY2946 185 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 16762266 Common - hypothetical protein STY3692 8 None None None 16761521 Common - hypothetical protein STY2855 79 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 16762958 Common nrfA cytochrome c nitrite reductase STY4475 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 16759768 Common yliD hypothetical ABC transporter permease protein STY0890 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16759943 Common - ABC transporter ATPase component STY1083 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 16759063 Common caiD carnitinyl-CoA dehydratase STY0080 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 16761527 Common trmD tRNA (guanine-N(1)-)-methyltransferase STY2861 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 16762104 Common rpsI 30S ribosomal protein S9 STY3524 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 16759499 Common - putative purine permease YbbY STY0572 50 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 16762097 Common - hypothetical protein STY3515 29 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 16762597 Pathogen waaL O-antigen ligase STY4082 4 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 16763270 Common - hypothetical protein STY4808 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 16763204 Common sgaU L-xylulose 5-phosphate 3-epimerase STY4743 37 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 16761072 Pathogen - hypothetical protein STY2357 3 None None None 16759294 Pathogen - hypothetical protein STY0342 1 None None None 16760597 Common topB DNA topoisomerase III STY1816 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 16759236 Common rcsF outer membrane lipoprotein STY0271 13 None None None 16763167 Common yjeM putative amino acid permease STY4705 43 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16760011 Common - putative oxidoreductase STY1170 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 16762541 Common - putative DNA-binding protein STY4005 43 COG2944 COG2944, Predicted transcriptional regulator Transcription 16759698 Common galM aldose 1-epimerase STY0806 94 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 16760603 Common - hypothetical protein STY1823 28 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 16761428 Common guaB inositol-5-monophosphate dehydrogenase STY2752 237 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 16763382 Common sthB putative fimbrial chaperone protein STY4943 25 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16759341 Common - AraC-family transcriptional regulator STY0395 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16763258 Common - hypothetical protein STY4797 13 None None None 16760066 Common - hypothetical protein STY1229 54 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 16761505 Common ung uracil-DNA glycosylase STY2840 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 16759125 Common ddl D-alanine--D-alanine ligase STY0150 217 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 161501919 Common - putrescine--2-oxoglutarate aminotransferase STY3396 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 16759612 Common ybeL hypothetical protein STY0704 21 None None None 16762425 Common glnA glutamine synthetase STY3874 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 16760292 Common - probable TonB-dependent receptor YncD precursor STY1478 118 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16759820 Common - probable integrase remnant STY0946 75 None None None 16763216 Common - hypothetical protein STY4755 3 None None None 16762478 Common yieG putative membrane transport protein STY3932 134 COG2252 COG2252, Permeases General function prediction only 16759870 Common - putative transcriptional regulator STY1005 160 COG1522 Lrp, Transcriptional regulators Transcription 16763322 Common - hypothetical protein STY4870 11 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 16759225 Common ldcC lysine decarboxylase STY0259 88 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 16760266 Common - putative phosphotransferase enzyme STY1450 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 16760965 Common cbiE cobalt-precorrin-6Y C(5)-methyltransferase STY2236 103 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 16762113 Common ttdB L(+)-tartrate dehydratase subunit beta STY3534 141 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 16762735 Common ftsX cell division protein FtsX STY4242 118 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 16761638 Common sitA Iron transport protein, periplasmic-binding protein STY2983 169 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 16762496 Common - hypothetical protein STY3949 19 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 16761235 Common menD 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase STY2540 98 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 16759184 Common yadB glutamyl-Q tRNA(Asp) synthetase STY0210 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 16759539 Common ybdF hypothetical protein STY0621 35 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 16759117 Common ftsI penicillin-binding protein 3 precursor STY0142 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 16759998 Common - hypothetical protein STY1156 12 None None None 16760213 Common - putative transcriptional regulator STY1390 79 COG1309 AcrR, Transcriptional regulator Transcription 16763345 Common - conserved hypothetical regulatory protein STY4900 14 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16759842 Pathogen - hypothetical protein STY0970 1 None None None 16762667 Common yhjY hypothetical protein STY4161 10 COG5571 COG5571, Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion Cell motility and secretion 16761892 Pathogen - hypothetical protein STY3278 1 None None None 16759436 Common ybaE putative solute-binding protein STY0498 51 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 16762797 Common yrfB hypothetical protein STY4306 6 None None None 16759754 Common - manganese transport regulator MntR STY0876 89 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 16759904 Common - putative secreted protein STY1043 4 None None None 16761907 Common ordL putative oxidoreductase STY3297 101 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 16761335 Common nupC nucleoside permease NupC STY2650 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 16762536 Common - hypothetical protein STY3998 17 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 16759314 Common crl DNA-binding transcriptional regulator Crl STY0364 13 None None None 16763295 Pathogen - hypothetical secreted protein STY4834 1 None None None 16760224 Common - hypothetical protein STY1401 189 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16760722 Common - hypothetical protein STY1962 16 COG4811 COG4811, Predicted membrane protein Function unknown 16759602 Common cobC alpha-ribazole-5'-phosphate phosphatase STY0694 167 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 16760180 Common fabI enoyl-(acyl carrier protein) reductase STY1352 230 COG0623 FabI, Enoyl- acyl-carrier-protein 16762313 Common btuB vitamin B12/cobalamin outer membrane transporter STY3744 129 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 16759915 Common - putative bacteriophage protein STY1054 6 None None None 16760658 Common cdtB putative toxin-like protein STY1886 7 None None None 16761839 Common pepP proline aminopeptidase P II STY3214 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 16762355 Common - ribulose-phosphate 3-epimerase STY3790 215 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 16763169 Common yjeP predicted mechanosensitive channel STY4707 181 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16762062 Common - D-alanyl-D-alanine carboxypeptidase/endopeptidase STY3479 109 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 16762347 Common yiiU hypothetical protein STY3782 21 COG3074 COG3074, Uncharacterized protein conserved in bacteria Function unknown 16761248 Common nuoG NADH dehydrogenase subunit G STY2553 187 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 16761007 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase STY2285 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 16759879 Common betA bacteriophage recombination protein STY1017 11 None None None 16762373 Common fieF ferrous iron efflux protein F STY3810 207 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 16760799 Pathogen - hypothetical protein STY2055 2 None None None 16760510 Common sseD putative pathogenicity island effector protein STY1719 4 None None None 16762802 Common damX hypothetical protein STY4311 15 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 16760806 Common - putative replication protein STY2062 25 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 16759159 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase 2 STY0185 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 16761855 Common - hypothetical protein STY3231 22 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 16760290 Common - putative NADP-dependent oxidoreductase STY1476 94 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 16762892 Common pepE peptidase E STY4407 34 COG3340 PepE, Peptidase E Amino acid transport and metabolism 16759986 Common hpaX putative 4-hydroxyphenylacetate permease STY1141 123 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16760695 Common fadR fatty acid metabolism regulator STY1934 62 COG2186 FadR, Transcriptional regulators Transcription 16759689 Common ybgF hypothetical protein STY0796 100 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 16760323 Common - putative multidrug efflux protein STY1517 107 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759596 Common dacA D-alanyl-D-alanine carboxypeptidase fraction A STY0688 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 16759807 Common ybjU L-allo-threonine aldolase, PLP-dependent STY0930 100 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 16761987 Common - hypothetical protein STY3392 52 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 16763346 Common - DNA-binding transcriptional activator BglJ STY4901 26 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16760679 Common - hydrogenase 1 large subunit STY1914 106 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 16761154 Common - putative lipoprotein STY2450 134 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 16761252 Common nuoB NADH dehydrogenase subunit B STY2557 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 16759351 Common - puative autotransporter/virulence factor STY0405 36 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16762334 Common - hypothetical protein STY3766 7 None None None 16761070 Pathogen - hypothetical protein STY2355 3 None None None 16759139 Common hofC type IV pilin biogenesis protein STY0164 144 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 16759532 Common ykgB hypothetical protein STY0614 26 COG3059 COG3059, Predicted membrane protein Function unknown 16759397 Common - phosphatidylglycerophosphatase A STY0459 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 16762965 Common gltP glutamate/aspartate:proton symporter STY4482 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 16762121 Common - hypothetical protein STY3543 8 None None None 16761872 Common - Holliday junction resolvase-like protein STY3250 181 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 16761484 Common yfhH putative DNA-binding transcriptional regulator STY2818 163 COG1737 RpiR, Transcriptional regulators Transcription 16760716 Common sdaA L-serine deaminase 1 STY1956 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 16760933 Common vsr patch repair protein STY2199 68 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 16762206 Common rffC TDP-fucosamine acetyltransferase STY3631 14 None None None 16761647 Common orgAa cell invasion protein STY2991 5 None None None 16760444 Common rstB sensor protein RstB STY1651 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16761280 Common argT lysine-arginine-ornithine-binding periplasmic protein precursor STY2585 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16759061 Common caiF DNA-binding transcriptional activator CaiF STY0078 4 None None None 16759963 Common tnpA transposase for insertion sequence element IS200 STY1108 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16761572 Common ygaF hypothetical protein STY2910 112 COG0579 COG0579, Predicted dehydrogenase General function prediction only 16761371 Common - hypothetical protein STY2690 4 COG3878 COG3878, Uncharacterized protein conserved in bacteria Function unknown 16759549 Common fepC iron-enterobactin transporter ATP-binding protein STY0634 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 16760200 Common pspE thiosulfate:cyanide sulfurtransferase (rhodanese) STY1375 70 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 16759390 Pathogen - hypothetical protein STY0450 1 None None None 16759616 Common gltJ glutamate/aspartate transport system permease protein GltJ STY0709 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 16762019 Common garD D-galactarate dehydratase STY3432 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 16759789 Common potH putrescine transporter subunit: membrane component of ABC superfamily STY0912 182 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 16762099 Common nanT putative sialic acid transporter STY3519 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16761384 Common - putative cobalamin adenosyltransferase STY2703 12 COG4812 EutT, Ethanolamine utilization cobalamin adenosyltransferase Amino acid transport and metabolism 16762953 Common - hypothetical protein STY4470 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 16762278 Common tnpA transposase STY3706 71 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760525 Common ttrB tetrathionate reductase subunit B STY1736 161 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16762074 Common - hypothetical protein STY3491 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 16762241 Common - DNA adenine methylase STY3667 98 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 16759723 Common uvrB excinuclease ABC subunit B STY0831 230 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 16761631 Common hypA hydrogenase nickel incorporation protein STY2976 88 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 16762142 Common prmA ribosomal protein L11 methyltransferase STY3563 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 16759418 Common - hypothetical protein STY0480 84 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 16759198 Common mtn 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase STY0229 116 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 16763173 Common artJ probable arginine-binding periplasmic protein STY4711 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16762489 Common recF recombination protein F STY3942 167 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 16759489 Common sfbB ABC transporter ATP-binding protein STY0559 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 16759165 Common gcd glucose dehydrogenase STY0191 59 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 16762484 Common yidC putative inner membrane protein translocase component YidC STY3938 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 16761062 Common - hypothetical protein STY2346 5 None None None 16762039 Common - putative acetyltransferase STY3455 93 COG3153 COG3153, Predicted acetyltransferase General function prediction only 16759601 Common ybeB hypothetical protein STY0693 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 16760773 Common - putative bacteriophage protein STY2030 7 None None None 16762913 Common malM maltose regulon periplasmic protein STY4428 17 None None None 16760034 Common - hypothetical protein STY1194 112 COG2353 COG2353, Uncharacterized conserved protein Function unknown 16760892 Common uvrC excinuclease ABC subunit C STY2154 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 16761819 Common - possible lipoprotein STY3194 185 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 16760553 Common btuE predicted glutathione peroxidase STY1769 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 16762946 Common soxS DNA-binding transcriptional dual regulator STY4463 135 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16761698 Common pcm protein-L-isoaspartate O-methyltransferase STY3051 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 16761243 Common nuoL NADH dehydrogenase subunit L STY2548 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 16761006 Common hisH imidazole glycerol phosphate synthase subunit HisH STY2284 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 16759211 Common - undecaprenyl pyrophosphate synthase STY0244 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 161501945 Common bssS biofilm formation regulatory protein BssS STY1199 11 None None None 16761756 Common fucU fuscose operon fucU protein STY3118 32 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 16760275 Common - putative DNA-binding protein STY1459 88 COG1396 HipB, Predicted transcriptional regulators Transcription 16761010 Common cld polysaccharide chain length regulator STY2288 16 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 16758999 Common yaaJ putative amino-acid transport protein STY0006 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 16759082 Common folA dihydrofolate reductase STY0102 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 16761386 Common - putative ethanolamine utilization protein EutP STY2705 18 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 16760418 Common - hypothetical protein STY1624 6 None None None 16760411 Common - hypothetical protein STY1617 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 16761286 Common - putative transcriptional regulator STY2591 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 161501908 Common - hypothetical protein STY3968 10 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 16761827 Common - hypothetical protein STY3202 11 None None None 16760972 Common pduB putative propanediol utilization protein PduB STY2244 21 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 16761306 Common yfcA hypothetical protein STY2614 157 COG0730 COG0730, Predicted permeases General function prediction only 16761173 Common - hypothetical protein STY2471 2 None None None 16760365 Common dmsB putative dimethyl sulphoxide reductase subunit STY1567 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16759797 Common artJ arginine-binding periplasmic protein 2 precursor STY0920 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16761272 Common - phosphodiesterase STY2577 40 COG0622 COG0622, Predicted phosphoesterase General function prediction only 16762256 Common nucD putative lysozyme STY3682 45 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 16759305 Common gmhA phosphoheptose isomerase STY0355 123 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 16761195 Common ompC outer membrane porin protein C STY2493 25 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 16762760 Common gntK gluconate kinase 1 STY4269 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 16760990 Common pduX hypothetical protein STY2263 17 COG4542 PduX, Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase Secondary metabolites biosynthesis, transport, and catabolism 16761652 Common - AraC-family transcriptional regulator STY2996 54 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16759102 Common thiP thiamin transporter membrane protein STY0124 180 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 16760864 Common cheZ chemotaxis regulator CheZ STY2124 44 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 16762984 Pathogen - hypothetical protein STY4500a 1 None None None 16760855 Common - hypothetical protein STY2113 54 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 16763376 Common rob right origin-binding protein STY4933 112 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16760616 Common - hypothetical protein STY1842 2 None None None 16760911 Pathogen - hypothetical protein STY2175 1 None None None 16761596 Common emrB multidrug resistance protein B STY2941 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762928 Common alr alanine racemase STY4443 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 16761553 Common - probable major tail tube protein STY2887 26 COG3498 COG3498, Phage tail tube protein FII General function prediction only 16759611 Common - putative sigma-54 dependent transcriptional regulator STY0703 167 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 16760083 Common thiK thiamin kinase STY1248 13 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 16759958 Common - hypothetical protein STY1099 19 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 16762180 Common - hypothetical protein STY3605 3 None None None 16763077 Common - putative phage tail protein STY4612 28 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 16759650 Common ybfA hypothetical protein STY0748 11 None None None 16761928 Common hyb0 hydrogenase 2 small subunit STY3321 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 16760670 Common hemA glutamyl-tRNA reductase STY1902 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 16760492 Common yscR type III secretion system protein STY1701 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 16761443 Common - putative anaerobic reductase component STY2773 30 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 16761037 Common wcaI predicted glycosyl transferase STY2318 97 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16761564 Common mig-14 putative transcriptional regulator STY2900 5 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 16759204 Common glnD PII uridylyl-transferase STY0237 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 16759383 Common tgt queuine tRNA-ribosyltransferase STY0443 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 16762994 Common - araC family regulatory protein STY4515 62 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16762003 Common - hypothetical protein STY3411 9 None None None 16759720 Common bioF 8-amino-7-oxononanoate synthase STY0828 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 16759098 Common araB ribulokinase STY0120 80 COG1069 AraB, Ribulose kinase Energy production and conversion 16761408 Common bcp thioredoxin-dependent thiol peroxidase STY2729 215 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16762183 Common uvrD DNA-dependent helicase II STY3608 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 16760422 Common - hypothetical protein STY1628 7 None None None 16762572 Common - putative beta-lactamase STY4057 30 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 16762303 Common rplA 50S ribosomal protein L1 STY3735 243 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 16759844 Common focA formate transporter STY0974 92 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 16759463 Common dnaX DNA polymerase III subunits gamma and tau STY0528 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 16760345 Common marB hypothetical protein STY1542 6 None None None 16761497 Common rseB periplasmic negative regulator of sigmaE STY2831 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 16760332 Common - hydrogenase isoenzyme formation protein STY1528 16 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 16761731 Common steF fimbrial subunit STY3090 15 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16761378 Common eutH hypothetical protein STY2697 18 COG3192 EutH, Ethanolamine utilization protein Amino acid transport and metabolism 16762022 Common - possible carbohydrate kinase STY3436 92 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 16761985 Common rpoD RNA polymerase sigma factor RpoD STY3390 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 16761279 Common hisJ histidine-binding periplasmic protein STY2584 174 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16760818 Common - hypothetical protein STY2074 8 None None None 16759338 Common - probable terminal oxidase subunit I STY0392 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 16761667 Common spaP surface presentation of antigens protein SpaP STY3013 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 16759175 Common staG putative fimbrial-like adhesin protein STY0201 3 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16759559 Common cstA carbon starvation protein A STY0644 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 16761622 Common hycI hydrogenase 3 maturation protease STY2967 36 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 16762820 Common prkB phosphoribulokinase STY4333 52 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 16759027 Common - putative secreted 5'-nucleotidase STY0040 141 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 16760702 Common - predicted isomerase/hydrolase STY1942 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 16762279 Common yifE hypothetical protein STY3707 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 16763195 Common yjfN hypothetical protein STY4734 8 None None None 16761965 Common - zinc transporter ZupT STY3368 109 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 16759730 Common MoaE molybdopterin synthase large subunit STY0840 158 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 16762132 Common mreC cell wall structural complex MreBCD transmembrane component MreC STY3553 133 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 16763033 Common - hypothetical protein STY4564 19 None None None 16761849 Common tnpA transposase for insertion sequence element IS200 STY3224 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16761900 Pathogen - hypothetical protein STY3290 1 None None None 16760662 Pathogen - putative pertussis-like toxin subunit STY1891 2 None None None 16761217 Common - putative MR-MLE-family protein STY2521 96 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16761616 Common ygaA anaerobic nitric oxide reductase transcription regulator STY2961 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 16762227 Common ilvD dihydroxy-acid dehydratase STY3653 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 16761464 Common asrC anaerobic sulfite reductase subunit C STY2796 104 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 16762529 Common - hypothetical protein STY3991 14 None None None 16762154 Common - possible transferase STY3579 9 None None None 16761228 Common - hypothetical protein STY2532 14 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 16760944 Pathogen - hypothetical protein STY2210 1 None None None 16763237 Common yjga hypothetical protein STY4776 62 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 16762877 Common - hypothetical protein STY4392 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 16760379 Common - putative secreted protein STY1583 18 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 16762492 Common - possible racemase STY3945 110 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16762464 Common glmU bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase STY3916 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 16762527 Common - putative carbohydrate kinase STY3989 191 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16762998 Common phoN nonspecific acid phosphatase precursor STY4519 35 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 16760769 Common - putative bacteriophage protein STY2026 13 None None None 16759017 Common bcfD fimbrial subunit STY0029 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16759865 Common - hypothetical protein STY0998 63 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 16759322 Common stbB fimbrial chaperone protein STY0372 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16762700 Common - gntR family regulatory protein STY4201 140 COG2188 PhnF, Transcriptional regulators Transcription 16759091 Common hepA ATP-dependent helicase HepA STY0111 129 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 16760333 Common hyaE2 hydrogenase-1 operon protein HyaE2 STY1529 14 None None None 16762656 Common - hypothetical protein STY4150 27 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 161501927 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase STY2610 81 COG4121 COG4121, Uncharacterized conserved protein Function unknown 16761888 Common mltC murein transglycosylase C STY3267 121 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16762328 Common katG catalase (hydroperoxidase I) STY3760 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 16762616 Common lctR DNA-binding transcriptional repressor STY4103 131 COG2186 FadR, Transcriptional regulators Transcription 16759939 Common pyrD dihydroorotate dehydrogenase 2 STY1079 228 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 16762681 Common yhjS hypothetical protein STY4178 16 None None None 16761536 Common recN recombination and repair protein STY2870 199 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 16762577 Common slmA nucleoid occlusion protein STY4062 66 COG1309 AcrR, Transcriptional regulator Transcription 16759362 Common psiF hypothetical protein STY0417 22 None None None 16762452 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA STY3904 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 16762106 Common - putative ATP/GTP-binding protein STY3526 103 COG1485 COG1485, Predicted ATPase General function prediction only 16759670 Pathogen - hypothetical protein STY0774 2 None None None 16760079 Common ptsG glucose-specific PTS system IIBC components STY1242 50 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 16760790 Pathogen - hypothetical protein STY2047 1 None None None 16762707 Common - putative methyltransferase STY4210 54 None None None 16760633 Common - hypothetical protein STY1860 224 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16759379 Common malZ maltodextrin glucosidase STY0439 158 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 16761764 Common - hypothetical protein STY3126 115 COG2962 RarD, Predicted permeases General function prediction only 16763065 Pathogen - hypothetical protein STY4599 1 None None None 16760446 Common fumC fumarate hydratase STY1653 209 COG0114 FumC, Fumarase Energy production and conversion 16760710 Common - hypothetical protein STY1950 173 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 16760136 Common oppA periplasmic oligopeptide-binding protein precursor STY1304 210 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 16760123 Common narH respiratory nitrate reductase 1 beta chain STY1289 149 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 16763287 Common - bacteriophage gene regulatory protein STY4826 9 None None None 16760930 Common - hypothetical protein STY2194 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 16759269 Common - hypothetical protein STY0306 3 None None None 16760159 Common trpH hypothetical protein STY1329 127 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 16762198 Common hemX putative uroporphyrinogen III C-methyltransferase STY3623 50 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 16760104 Common - hypothetical protein STY1269 59 COG2850 COG2850, Uncharacterized conserved protein Function unknown 16761709 Common ygbF hypothetical protein STY3064 31 None None None 16762404 Common ygjM hypothetical protein STY3848 31 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 16759705 Common ybhT hypothetical protein STY0813 6 None None None 16760394 Pathogen - hypothetical protein STY1599 1 None None None 16759273 Common - probable secreted protein STY0312 2 None None None 16760382 Common tqsA putative transport protein STY1587 182 COG0628 PerM, Predicted permease General function prediction only 16763083 Common - putative regulatory protein STY4618 7 None None None 16761874 Common pilT Type II secretion, ATP-binding, protein STY3252 207 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 16762081 Common - putative ABC transporter ATP-binding protein YhbG STY3498 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 16759247 Common gloB predicted hydroxyacylglutathione hydrolase STY0282 202 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 16760089 Common - putative secreted protein STY1254 11 None None None 16760601 Common ansA cytoplasmic asparaginase I STY1820 140 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 16760976 Common pduG PduG protein STY2248 12 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 16759888 Common - putative methyltransferase STY1026 10 None None None 16759282 Pathogen - hypothetical protein STY0322 1 None None None 16759857 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase STY0990 138 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 16762272 Common - putative phage tail protein STY3698 19 None None None 16760326 Common - putative alcohol dehydrogenase STY1520 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 16759718 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase STY0826 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 16761303 Common fabB 3-oxoacyl-(acyl carrier protein) synthase I STY2609 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16759162 Common speE spermidine synthase STY0188 128 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 16763262 Common pyrL pyrBI operon leader peptide STY4800a 4 None None None 16760354 Common - hypothetical protein STY1552 7 None None None 16759639 Common ybfE LexA regulated protein STY0733 21 None None None 16760735 Common - hypothetical protein STY1978 83 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 16761700 Common truD tRNA pseudouridine synthase D STY3053 87 COG0585 COG0585, Uncharacterized conserved protein Function unknown 16763017 Common pilR hypothetical protein STY4546 11 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 16762932 Common - hypothetical protein STY4447 34 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 16760081 Common - putative lipoprotein STY1246 10 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 16762584 Common coaD phosphopantetheine adenylyltransferase STY4069 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 16759056 Common citX2 citx protein STY0071 25 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 16760980 Common pduL hypothetical protein STY2252 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 16761452 Common fdx ferredoxin STY2784 83 COG0633 Fdx, Ferredoxin Energy production and conversion 16760459 Common ydgQ SoxR-reducing system protein RsxE STY1668 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 16762269 Common pin DNA-invertase STY3695 136 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 16760727 Common - hypothetical protein STY1968 4 None None None 16762073 Common - possible exported protein STY3490 73 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 16761119 Common - FAA-hydrolase-family protein STY2407 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 16760485 Common ydhC inner membrane transport protein YdhC STY1694 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762980 Common melA alpha-galactosidase STY4497 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 16759193 Common hemL glutamate-1-semialdehyde aminotransferase STY0223 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 16761256 Common - aminotransferase AlaT STY2561 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 16759679 Common cydA cytochrome d ubiquinol oxidase subunit I STY0786 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 16762472 Common pstS phosphate transporter subunit STY3926 133 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 161501942 Common hrpA ATP-dependent RNA helicase HrpA STY1428 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 16759783 Common ybjC predicted inner membrane protein STY0906 5 None None None 16760009 Common - putative secreted protein STY1168 12 None None None 16759201 Common yaeG carbohydrate diacid transcriptional activator CdaR STY0232 49 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 16761492 Common era GTP-binding protein Era STY2826 228 COG1159 Era, GTPase General function prediction only 16762848 Common rplV 50S ribosomal protein L22 STY4363 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 16761784 Common - possible lipoprotein STY3150 14 None None None 16763148 Pathogen - hypothetical protein STY4686 3 None None None 16760296 Pathogen - hypothetical protein STY1482 1 None None None 16759581 Common citF citrate lyase alpha chain STY0670 31 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 16762441 Common rbsK ribokinase STY3892 195 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16762659 Common cspA major cold shock protein STY4153 181 COG1278 CspC, Cold shock proteins Transcription 16761438 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase STY2768 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 16760049 Common flgA flagellar basal body P-ring biosynthesis protein FlgA STY1212 29 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 16761111 Common yohC hypothetical protein STY2399 24 None None None 16762211 Common - lipopolysaccharide biosynthesis protein WzzE STY3636 15 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 16760151 Common - hypothetical protein STY1321 25 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 16761052 Common yegE hypothetical protein STY2336 193 COG3447 COG3447, Predicted integral membrane sensor domain Signal transduction mechanisms 16759169 Common yadH ABC transporter integral membrane protein STY0195 153 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 16759387 Common - hypothetical protein STY0447 34 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 16761912 Common exuT hexuronate transporter STY3305 183 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16763279 Common - putative inner membrane protein STY4817 66 COG0795 COG0795, Predicted permeases General function prediction only 16761584 Common - hypothetical protein STY2925 11 COG4575 ElaB, Uncharacterized conserved protein Function unknown 16760118 Common - predicted invasin STY1284 14 None None None 16760717 Common - hypothetical protein STY1957 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16761578 Common - putative transcriptional regulator STY2917 83 COG0640 ArsR, Predicted transcriptional regulators Transcription 16762399 Common fdhE formate dehydrogenase accessory protein FdhE STY3843 42 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 16763040 Common - hypothetical protein STY4572 20 None None None 16762621 Common - hypothetical protein STY4108 5 None None None 16761284 Common - putative amino acid transporter STY2589 150 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16761539 Common - hypothetical protein STY2873 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 16759941 Common - hypothetical protein STY1081 63 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 16761336 Common yfeA hypothetical protein STY2651 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16760093 Common lolD lipoprotein transporter ATP-binding subunit STY1258 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 16759625 Common nagD UMP phosphatase STY0719 109 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 16761314 Common - hypothetical protein STY2622 15 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 16763141 Pathogen - hypothetical protein STY4679 1 None None None 16763274 Common - putative acetyltransferase STY4812 66 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 16761085 Common - putative hydrolase STY2372 16 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 16760590 Common astD aldehyde dehyrogenase STY1809 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16762026 Common gatB galactitol-specific PTS system component IIB STY3442 15 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 16761069 Common - hypothetical protein STY2353 2 None None None 16762854 Common rplX 50S ribosomal protein L24 STY4369 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 16761046 Common wzb tyrosine phosphatase STY2330 118 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 16759213 Common yaeL zinc metallopeptidase STY0246 214 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 16759292 Common - hypothetical protein STY0338 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 16759978 Common hpaC 4-hydroxyphenylacetate 3-monooxygenase coupling protein STY1130 99 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 16759954 Common - hypothetical protein STY1095 59 COG1289 COG1289, Predicted membrane protein Function unknown 16763201 Common sgaB L-ascorbate-specific enzyme IIB component of PTS STY4740 16 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 16762693 Common yhjE hypothetical metabolite transport protein STY4194 122 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16759044 Common - hypothetical protein STY0059 4 None None None 16762285 Common zraP zinc resistance protein STY3713 6 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 16763038 Common - hypothetical protein STY4570 21 None None None 16760999 Common - putative transcriptional regulator STY2278 159 COG0583 LysR, Transcriptional regulator Transcription 16759506 Common - hypothetical protein STY0579 7 None None None 16763374 Common trpR Trp operon repressor STY4930 22 COG2973 TrpR, Trp operon repressor Transcription 16759104 Common yabN putative ABC transporter periplasmic solute binding protein STY0127 84 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 16758997 Common thrC threonine synthase STY0004 158 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 16759861 Common mukF condesin subunit F STY0994 19 COG3006 MukF, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 16759298 Common tcfD putative fimbrail protein STY0348 4 None None None 16762665 Common yiaC hypothetical protein STY4159 57 COG0456 RimI, Acetyltransferases General function prediction only 16759039 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase STY0054 211 COG0196 RibF, FAD synthase Coenzyme metabolism 16761844 Common rpiA ribose-5-phosphate isomerase A STY3219 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 16761972 Common - hypothetical protein STY3377 12 None None None 16760924 Common fliQ flagellar biosynthesis protein FliQ STY2188 86 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 16759507 Common arcC carbamate kinase STY0580 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 16763107 Common cI phage repressor protein cI STY4644 11 COG2932 COG2932, Predicted transcriptional regulator Transcription 16763113 Common vexE Vi polysaccharide export protein STY4651 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 16763127 Common - hypothetical protein STY4665 25 None None None 16760680 Common hyaC hydrogenase 1 b-type cytochrome subunit STY1915 46 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 16763005 Common - hypothetical protein STY4528 21 None None None 16760689 Common mltE membrane-bound lytic murein transglycosylase E STY1927 66 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16759933 Common - hypothetical protein STY1072 10 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 16763187 Common rnr exoribonuclease R STY4725 203 COG0557 VacB, Exoribonuclease R Transcription 16762403 Common ygjN hypothetical protein STY3847 13 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 16761747 Common ygdH hypothetical protein STY3108 49 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 16760845 Common ruvA Holliday junction DNA helicase motor protein STY2103 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 16762590 Pathogen - hypothetical protein STY4075 1 COG2327 WcaK, Uncharacterized conserved protein Function unknown 16762646 Common malS periplasmic alpha-amylase precursor STY4134 148 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 16761778 Common thyA thymidylate synthase STY3142 138 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 16761702 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase STY3055 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 16760873 Common flhC transcriptional activator FlhC STY2133 27 None None None 16759431 Common hupB transcriptional regulator HU subunit beta STY0493 200 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 16761508 Common - hypothetical protein STY2843 40 COG3148 COG3148, Uncharacterized conserved protein Function unknown 16762978 Common adi arginine decarboxylase STY4495 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 16759765 Common - glutathione transporter ATP-binding protein STY0887 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 16761566 Common tctD transcriptional regulator STY2904 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16759513 Common ybcI hypothetical protein STY0586 18 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 16760929 Common - mannosyl-3-phosphoglycerate phosphatase STY2193 29 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 16762836 Common rpsG 30S ribosomal protein S7 STY4351 245 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 16762807 Common yhfL hypothetical protein STY4316 6 None None None 16760278 Pathogen sifB secreted effector protein STY1462 1 None None None 16759643 Common - possible 5-nitroimidazole antibiotic resistance STY0737 33 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 16763387 Common - hypothetical protein STY4948 4 None None None 16762517 Common yidF hypothetical protein STY3976 21 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 16762612 Common - putative racemase STY4099 134 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16761352 Common crr glucose-specific PTS system component STY2670 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 16759068 Common fixA putative electron transfer flavoprotein FixA STY0085 151 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 16759881 Pathogen kil Rac prophage killing protein STY1019 3 None None None 16760479 Common rnt ribonuclease T STY1688 61 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 16762315 Common yijD hypothetical protein STY3746 15 None None None 16761024 Common rfbF glucose-1-phosphate cytidylyltransferase STY2302 157 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 16763329 Pathogen - hypothetical protein STY4879 1 None None None 16763300 Common - putative outer membrane protein STY4846 8 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 16762841 Common hopD Type III leader peptidase STY4356 106 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16763368 Common smp hypothetical protein STY4924 18 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 16762348 Common glpF glycerol uptake facilitator protein STY3783 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 16760194 Common sapA peptide transport periplasmic protein SapA precursor STY1369 195 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 16761343 Common yfeN hypothetical protein STY2659 8 None None None 16761713 Common - hypothetical protein STY3068 42 None None None 16762558 Common - putative DNA-binding protein STY4036 61 COG3943 COG3943, Virulence protein General function prediction only 16761421 Common - hypothetical protein STY2744 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16760960 Common cbiL cobalt-precorrin-2 C(20)-methyltransferase STY2228 114 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 16761932 Common - hypothetical protein STY3329 3 None None None 16761390 Common talA transaldolase A STY2710 187 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 16760008 Common - hypothetical protein STY1167 18 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 16761181 Common ccmB1 heme exporter protein B1 STY2479 74 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 16761857 Common - possible ABC-transport protein, ATP-binding component STY3233 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 16760931 Common - hypothetical protein STY2195 5 COG5475 COG5475, Uncharacterized small protein Function unknown 16760532 Common lppB major outer membrane lipoprotein STY1746 19 COG4238 COG4238, Murein lipoprotein Cell envelope biogenesis, outer membrane 16760017 Common csgF curli assembly protein CsgF STY1177 9 None None None 16760651 Common pagC outer membrane invasion protein STY1878 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16762786 Common envZ osmolarity sensor protein STY4295 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16761415 Common uraA uracil transporter STY2738 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 16763272 Pathogen - hypothetical protein STY4810 1 None None None 16762967 Common fdhF formate dehydrogenase H STY4484 198 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 16763282 Common - integrase STY4821 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 16762095 Common codB cytosine permease STY3513 69 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 16759136 Common yacF hypothetical protein STY0161 44 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 16759556 Common entB isochorismatase STY0641 77 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 16762366 Common - hypothetical protein STY3803 21 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 16763133 Common - hypothetical protein STY4671 8 None None None 16763025 Common - hypothetical protein STY4554 4 None None None 16763197 Common yjfP predicted hydrolase STY4736 23 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 16762260 Common - putative phage tail protein STY3686 15 None None None 16759734 Common ybhP hypothetical protein STY0848 64 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 16762028 Common gatD galactitol-1-phosphate dehydrogenase STY3444 211 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 16763120 Common insA insertion element IS1 protein STY4658 14 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760889 Pathogen - hypothetical protein STY2151 1 None None None 16760052 Common flgD flagellar basal body rod modification protein STY1215 100 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 16760608 Common - putative outer membrane protein STY1830 37 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 16762729 Common - hypothetical protein STY4236 16 COG3714 COG3714, Predicted membrane protein Function unknown 16761260 Common - hypothetical protein STY2565 18 COG3013 COG3013, Uncharacterized conserved protein Function unknown 16759586 Common dpiA DNA-binding response regulator in two-component regulatory system with citA STY0675 185 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 16763254 Common treC trehalose-6-phosphate hydrolase STY4793 166 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 16761719 Common cysI sulfite reductase (NADPH) hemoprotein alpha subunit STY3075 143 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 16761619 Common hypf hydrogenase maturation protein STY2964 119 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 16760020 Common csgB curlin minor subunit STY1180 18 None None None 16761426 Pathogen - hypothetical protein STY2750 1 None None None 16759071 Common fixX ferredoxin like protein FixX STY0088 35 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 16763226 Common tnpA transposase for insertion sequence element is200 STY4765 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16763315 Common trpS2 tryptophanyl-tRNA synthetase II STY4863 235 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16761215 Common - putative aldolase STY2519 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 16759989 Common yccD chaperone-modulator protein CbpM STY1147 8 None None None 16760027 Common mdoG glucan biosynthesis protein G STY1187 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 16762599 Common waaF ADP-heptose:LPS heptosyltransferase II STY4084 105 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 16762779 Common - hypothetical protein STY4288 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 16763104 Common - hypothetical protein STY4641 3 None None None 16762678 Common - hypothetical protein STY4175 3 None None None 16761673 Common invA possible secretory protein (associated with virulence) STY3019 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 16761160 Common yejG hypothetical protein STY2456 11 None None None 16760839 Common msbB lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase STY2097 82 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 16763324 Common - hypothetical protein STY4872 46 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 16763350 Common - hypothetical protein STY4905 9 None None None 16762769 Common glpE thiosulfate sulfurtransferase STY4278 96 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 16761905 Common - possible amino acid transport protein STY3295 146 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16759982 Common hpcB 3,4-dihydroxyphenylacetate 2,3-dioxygenase STY1137 25 COG3384 COG3384, Uncharacterized conserved protein Function unknown 16760915 Common fliH flagellar assembly protein H STY2179 33 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 16761227 Common arnT 4-amino-4-deoxy-L-arabinose transferase STY2531 67 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 16762236 Common cII regulatory protein cII STY3662 8 None None None 16761514 Common clpB protein disaggregation chaperone STY2849 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 16759380 Common - probable peroxidase STY0440 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16760284 Common srfC putative virulence effector protein STY1470 14 COG4458 SrfC, Uncharacterized protein conserved in bacteria, putative virulence factor Function unknown 16760503 Pathogen ssaI putative pathogenicity island protein STY1712 1 None None None 16759996 Common - hypothetical protein STY1154 7 None None None 16761823 Common recJ ssDNA exonuclease RecJ STY3198 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 16762770 Common glpG predicted intramembrane serine protease STY4279 113 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 16759254 Common - hypothetical protein STY0289 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 16761291 Common accD acetyl-CoA carboxylase subunit beta STY2597 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 16761322 Common pgtB phosphoglycerate transport system sensor protein PgtB STY2634 209 COG4192 COG4192, Signal transduction histidine kinase regulating phosphoglycerate transport system Signal transduction mechanisms 16760004 Common - putative transcriptional regulator STY1163 104 COG1737 RpiR, Transcriptional regulators Transcription 16761544 Common - putative type I secretion protein STY2878 123 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16762601 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase STY4086 192 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 16762245 Common - possible lipoprotein STY3671 4 None None None 16761393 Common - hypothetical protein STY2713 15 None None None 16763094 Pathogen - hypothetical protein STY4629 2 None None None 16760646 Pathogen - hypothetical protein STY1874a 1 None None None 16760810 Common - putative regulator STY2066 17 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 16760301 Common narY respiratory nitrate reductase 2 beta chain STY1487 150 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 16761105 Common yehW putative permease transmembrane component STY2392 131 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 16759408 Common phnW 2-aminoethylphosphonate:pyruvate aminotransferase STY0470 167 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 16763289 Common - phage DNA binding protein STY4828 34 COG3311 AlpA, Predicted transcriptional regulator Transcription 16759447 Common ybaZ putative methylated-DNA methyltransferase STY0510 152 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 16762284 Common hydH sensor protein ZraS STY3712 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16760827 Common holE DNA polymerase III subunit theta STY2082 12 None None None 16761167 Common yejK nucleoid-associated protein NdpA STY2463 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 16763252 Common nrdD anaerobic ribonucleoside triphosphate reductase STY4791 98 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 16763230 Common ytfN hypothetical protein STY4769 101 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 16760820 Common - hypothetical protein STY2075 3 None None None 16762259 Common - putative phage tail protein STY3685 17 None None None 16760300 Common narW respiratory nitrate reductase 2 delta chain STY1486 53 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 16761656 Common sicP chaperone (associated with virulence) STY3002 3 None None None 16760111 Common - putative secreted protein STY1276 20 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 16761664 Common spaS surface presentation of antigens protein SpaS STY3010 124 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 16762508 Common ccmF2 cytochrome c-type biogenesis protein F2 STY3964 157 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16759467 Common adk adenylate kinase STY0532 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 16761110 Common dld D-lactate dehydrogenase STY2397 62 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 16762756 Common - putative acetyltransferase YhhY STY4265 69 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 16762413 Common yihR hypothetical protein STY3858 30 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 16759747 Common glnP glutamine ABC transporter permease protein STY0867 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 16761125 Common cdd cytidine deaminase STY2413 32 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 16763354 Common - nucleotidase STY4909 117 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 16761602 Common csrA carbon storage regulator STY2947 81 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 16759486 Common - hypothetical protein STY0554 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 16761755 Common fucK L-fuculokinase STY3117 181 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16760207 Common - murein peptide amidase A STY1383 18 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 16759665 Common - hypothetical protein STY0767 2 None None None 16762985 Common dcuR DNA-binding response regulator in two-component regulatory system with DcuS STY4501 160 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 16761886 Common mutY adenine DNA glycosylase STY3265 231 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 16761367 Common - putative acetyltransferase STY2686 86 COG0456 RimI, Acetyltransferases General function prediction only 16761207 Common - putative transcriptional regulator STY2510 190 COG0583 LysR, Transcriptional regulator Transcription 16759218 Common lpxA UDP-N-acetylglucosamine acyltransferase STY0251 154 COG1043 LpxA, Acyl- acyl carrier protein 16760910 Common yedF hypothetical protein STY2174 30 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 16761479 Common yfhD putative transglycosylase STY2813 92 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 16760832 Common yebF hypothetical protein STY2087 8 None None None 16761831 Common - hypothetical protein STY3206 16 COG3097 COG3097, Uncharacterized protein conserved in bacteria Function unknown 16759569 Common tnpA transposase for insertion sequence element IS200 STY0657 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760129 Common - hypothetical protein STY1296 130 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 16760755 Pathogen - putative DNA-binding protein STY2007 3 None None None 16759740 Common ybiH putative DNA-binding transcriptional regulator STY0854 31 COG1309 AcrR, Transcriptional regulator Transcription 16762353 Common yiiQ hypothetical protein STY3788 11 None None None 16759478 Common - hypothetical protein STY0546 35 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16759891 Pathogen - putative bacteriophage protein STY1029 1 None None None 16761239 Common - ribonuclease Z STY2544 131 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 16761047 Common wza putative polysaccharide export protein STY2331 125 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 16759577 Common rna ribonuclease I STY0666 31 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 16759492 Common - DNA-binding transcriptional activator of the allD operon STY0562 156 COG0583 LysR, Transcriptional regulator Transcription 16759875 Common - putative bacteriophage protein STY1013 4 None None None 16761156 Common yejA putative transport system periplasmic binding protein STY2452 164 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 16761689 Common hyi hypothetical protein STY3040 74 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 16762498 Common torS hybrid sensory histidine kinase TorS STY3951 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16762016 Common - glycerate kinase I STY3429 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 16759196 Common yadS hypothetical protein STY0227 128 COG2860 COG2860, Predicted membrane protein Function unknown 16762875 Common fmt methionyl-tRNA formyltransferase STY4390 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 16759530 Common ykgC pyridine nucleotide-disulfide oxidoreductase STY0612 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 16759618 Common lnt apolipoprotein N-acyltransferase STY0711 166 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 16763031 Common - hypothetical protein STY4562 33 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 16761610 Common srlB glucitol/sorbitol-specific PTS system component IIA STY2955 22 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 16761837 Common - hypothetical protein STY3212 134 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 16759759 Common - hypothetical protein STY0881 95 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16761134 Common yeiB hypothetical protein STY2426 50 COG2311 COG2311, Predicted membrane protein Function unknown 16761510 Common pssA phosphatidylserine synthase STY2845 29 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 16763213 Common ytfB hypothetical protein STY4752 14 COG3061 OapA, Cell envelope opacity-associated protein A Cell envelope biogenesis, outer membrane 16762152 Common fadB multifunctional fatty acid oxidation complex subunit alpha STY3577 187 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 16759627 Common nagA N-acetylglucosamine-6-phosphate deacetylase STY0721 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 16761382 Common eutN putative ethanolamine utilization protein EutN STY2701 47 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 16760880 Common yecI ferritin-like protein STY2141 69 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 16761814 Pathogen - hypothetical protein STY3188 4 None None None 16762460 Common atpG F0F1 ATP synthase subunit gamma STY3912 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 16762140 Common - hypothetical protein STY3561 19 COG3924 COG3924, Predicted membrane protein Function unknown 16760527 Common ttrA tetrathionate reductase subunit A STY1738 78 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16762243 Common - hypothetical protein STY3669 3 None None None 16759687 Common tolB translocation protein TolB STY0794 158 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 16762149 Common trkH potassium transporter STY3574 153 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 16759779 Common - putative tetR-family transcriptional regulator STY0902 25 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 16760677 Common - translation-associated GTPase STY1910 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 16760061 Common tnpA transposase for insertion sequence element IS200 STY1225 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762989 Common - hypothetical protein STY4510 6 None None None 161501947 Common moaD molybdopterin synthase small subunit STY0839 78 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 16762057 Common folP dihydropteroate synthase STY3473 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 16760693 Common dadA D-amino acid dehydrogenase small subunit STY1931 131 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 16762948 Common - putative glutathione S transferase STY4465 86 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16760890 Pathogen - hypothetical protein STY2152 1 None None None 16762422 Common - hypothetical protein STY3869 6 None None None 16760360 Common - putative secreted protein STY1560 11 None None None 16762371 Common sbp sulfate transporter subunit STY3808 91 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 16760708 Common fadD long-chain-fatty-acid--CoA ligase STY1948 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16759859 Common ycbC hypothetical protein STY0992 77 COG1434 COG1434, Uncharacterized conserved protein Function unknown 16762482 Common yidY multidrug efflux system protein MdtL STY3936 225 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759725 Common - hypothetical protein STY0835 92 COG0391 COG0391, Uncharacterized conserved protein Function unknown 16762268 Common - hypothetical protein STY3694 5 None None None 16761190 Common eco ecotin precursor STY2488 23 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 16763339 Common mdoB phosphoglycerol transferase I STY4894 45 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 16759304 Common fadE acyl-CoA dehydrogenase STY0354 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 16762130 Common maf Maf-like protein STY3551 199 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 16761842 Common - predicted ligase STY3217 189 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 16762911 Common malK maltose/maltodextrin transporter ATP-binding protein STY4426 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 16762924 Common yjbN tRNA-dihydrouridine synthase A STY4439 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 16760539 Common - putative transporter STY1755 156 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 16762860 Common rpsE 30S ribosomal protein S5 STY4375 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 16760420 Common - tail core protein STY1626 25 COG3498 COG3498, Phage tail tube protein FII General function prediction only 16761060 Common baeR DNA-binding response regulator in two-component regulatory system with BaeS STY2344 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16761482 Common - putative PTS system IIBC component STY2816 48 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 16760775 Common - putative bacteriophage protein STY2032 6 None None None 16762076 Common - putative calcium/sodium:proton antiporter STY3493 130 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 16759154 Common yacH hypothetical protein STY0180 30 None None None 16763158 Common ecnB entericidin B membrane lipoprotein STY4696 9 COG5510 COG5510, Predicted small secreted protein Function unknown 16760209 Common - putative oxidoreductase STY1385 8 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 16760551 Common nlpC putative lipoprotein STY1767 132 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 16760182 Common - hypothetical protein STY1354 9 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16759457 Common acrR DNA-binding transcriptional repressor STY0521 124 COG1309 AcrR, Transcriptional regulator Transcription 16761948 Common sufI repressor protein for FtsI STY3349 66 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 16761027 Common rfbA TDP-glucose pyrophosphorylase STY2305 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 16762569 Common rpoZ DNA-directed RNA polymerase subunit omega STY4051 110 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 16759223 Common tnpA transposase for insertion sequence element IS200 STY0256 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762564 Common - putative purine permease STY4046 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 16762506 Common ccmD2 heme exporter protein D2 STY3962 17 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 16761073 Pathogen - hypothetical protein STY2358 5 None None None 16759877 Common - putative bacteriophage protein STY1015 14 None None None 16762115 Common - possible membrane transport protein STY3536 192 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 16761636 Common fhlA transcriptional activator of the formate hydrogenlyase system STY2981 172 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 16762233 Pathogen - hypothetical protein STY3659 1 None None None 16760543 Common - predicted inner membrane protein STY1759 75 COG0628 PerM, Predicted permease General function prediction only 16762345 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase STY3780 99 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 16761436 Common - hypothetical protein STY2766 60 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 16761662 Common sipB pathogenicity island 1 effector protein STY3008 10 None None None 16760013 Common - putative hydrolase STY1173 35 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 16760268 Common - hypothetical protein STY1452 90 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 16761233 Common menB naphthoate synthase STY2537 179 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 16763256 Common treR trehalose repressor STY4795 126 COG1609 PurR, Transcriptional regulators Transcription 16762726 Common yhhP cell developmental protein SirA STY4233 92 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 16761141 Common lysP lysine transporter STY2435 166 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 16761894 Common - bacteriocin immunity protein STY3281 8 None None None 16761916 Common - hypothetical protein STY3309 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 16763180 Common hfq RNA-binding protein Hfq STY4718 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 16762676 Common dppF dipeptide transporter ATP-binding subunit STY4172 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 16759614 Common gltL glutamate/aspartate transport ATP-binding protein GltL STY0707 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 16762172 Common yigL predicted hydrolase STY3597 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16759832 Common lolA outer-membrane lipoprotein carrier protein STY0959 68 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 16763151 Common groES co-chaperonin GroES STY4689 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 16761790 Common - possible regulatory protein STY3156 127 COG1609 PurR, Transcriptional regulators Transcription 16759324 Pathogen - possible transmembrane regulator STY0374 6 COG3710 CadC, DNA-binding winged-HTH domains Transcription 16759936 Pathogen - hypothetical protein STY1076 2 None None None 16762894 Common - hypothetical protein STY4409 30 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 16759343 Common - RhtC-like transporter STY0397 122 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 16759822 Common - hypothetical protein STY0948 63 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 16762525 Common ilvN acetolactate synthase 1 regulatory subunit STY3987 118 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 16760576 Common katE hydroperoxidase II STY1793 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 16761593 Common - putative transmembrane transport protein STY2938 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759401 Common xseB exodeoxyribonuclease VII small subunit STY0463 136 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 16760462 Common gst glutathionine S-transferase STY1671 82 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16761853 Common - hypothetical protein STY3229 19 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 16759924 Common - putative bacteriophage protein STY1063 6 None None None 16759312 Common gpt xanthine-guanine phosphoribosyltransferase STY0362 65 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 16759919 Common - hypothetical protein STY1058 14 None None None 16760955 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase STY2221 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 16761658 Common sipF acyl carrier protein STY3004 118 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16759912 Common - putative bacteriophage protein STY1051 7 None None None 16760629 Pathogen - putative regulatory protein STY1856 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16760311 Common hlyE hemolysin E STY1498 2 None None None 16759326 Common - putative rtn protein STY0376 160 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 16759649 Common kdpA potassium-transporting ATPase subunit A STY0747 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 16761644 Common sprA possible AraC-family transcriptional regulator STY2988 33 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16759608 Common - putative hydrolase N-terminus STY0700 56 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 16760797 Common mokW host cell-killing modulation protein STY2054A 6 None None None 161501940 Common marR DNA-binding transcriptional repressor MarR STY1540 90 COG1846 MarR, Transcriptional regulators Transcription 16759805 Common - putative oxidoreductase STY0928 122 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16759917 Common - putative bacteriophage protein STY1056 5 None None None 16762795 Common yrfD hypothetical protein STY4304 10 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 16760804 Pathogen - hypothetical protein STY2060 3 None None None 16759814 Common ybjY macrolide transporter subunit MacA STY0937 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 16760887 Pathogen - hypothetical protein STY2148 1 None None None 16760286 Common srfA putative virulence effector protein STY1472 11 None None None 16760656 Common envE putative lipoprotein STY1882 7 None None None 16760505 Common ssaG putative pathogenicity island protein STY1714 6 None None None 16761406 Common dapA dihydrodipicolinate synthase STY2727 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 16762804 Common rpe ribulose-phosphate 3-epimerase STY4313 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 16759115 Common mraW S-adenosyl-methyltransferase MraW STY0140 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 16760377 Common tnpA transposase for insertion sequence element IS200 STY1580 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762494 Common yidA predicted hydrolase STY3947 146 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16761461 Common - hypothetical protein STY2793 103 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 16761349 Common cysZ putative sulfate transport protein CysZ STY2665 47 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 16762392 Common - hypothetical protein STY3834 7 None None None 16763366 Common yafM hypothetical protein STY4922 32 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760058 Common flgJ peptidoglycan hydrolase STY1221 74 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 16762684 Common bcsA cellulose synthase catalytic subunit STY4181 119 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16759025 Pathogen - putative transcriptional regulator STY0038 2 COG3710 CadC, DNA-binding winged-HTH domains Transcription 16761817 Common - hypothetical protein STY3192 8 None None None 16762543 Common - putative glycosyl hydrolase STY4009 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 16759093 Common - putative IS element transposase STY0114 70 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762586 Common waaQ lipopolysaccharide core biosynthesis protein STY4071 103 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 16760738 Common yebU rRNA (cytosine-C(5)-)-methyltransferase RsmF STY1981 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 16759598 Common mrdB cell wall shape-determining protein STY0690 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 16760906 Common fliT flagellar biosynthesis protein FliT STY2170 10 None None None 16761671 Common spaI ATP synthase SpaL STY3017 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 16759988 Common - hypothetical protein STY1143 127 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 16759364 Common proC pyrroline-5-carboxylate reductase STY0419 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 16759450 Common rpmJ 50S ribosomal protein L36 STY0513 60 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 16762294 Common thiE thiamine-phosphate pyrophosphorylase STY3722 202 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 16759177 Common staE putative fimbrial protein STY0203 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760913 Common fliF flagellar MS-ring protein STY2177 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 16759692 Common ybgR zinc transporter ZitB STY0799 189 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 16759540 Common - putative tetR-family transcriptional regulator STY0622 54 COG1309 AcrR, Transcriptional regulator Transcription 16762466 Common stgA probable fimbrial subunit protein STY3918 23 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760787 Common - putative endolysin STY2044 19 COG4678 COG4678, Muramidase (phage lambda lysozyme) Carbohydrate transport and metabolism 16761254 Pathogen - hypothetical protein STY2559 1 None None None 16761466 Common csiE stationary phase inducible protein CsiE STY2800 13 COG3711 BglG, Transcriptional antiterminator Transcription 16760044 Common - hypothetical protein STY1206 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 16759494 Common gcl glyoxylate carboligase STY0565 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 16762504 Common ccmB2 heme exporter protein B2 STY3960 74 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 16759336 Common mod type III restriction-modification system StyLTI enzyme mod STY0388 92 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 16763115 Common vexC Vi polysaccharide export ATP-binding protein STY4653 165 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 16763239 Common cybC soluble cytochrome b562 STY4778 11 COG3783 CybC, Soluble cytochrome b562 Energy production and conversion 16762169 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase STY3594 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 16762737 Pathogen - hypothetical protein STY4246 1 None None None 16760567 Common - putative outer membrane protein STY1784 35 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 16760664 Common tnpA transposase for insertion sequence element IS200 STY1895 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762661 Common yiaF hypothetical protein STY4155 12 None None None 16763063 Pathogen - hypothetical protein STY4596 2 None None None 16759863 Common mukB cell division protein MukB STY0996 29 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 16762203 Common - 4-alpha-L-fucosyltransferase STY3628 18 None None None 16761925 Common hybC hydrogenase 2 large subunit STY3318 108 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 16759013 Pathogen - hypothetical protein STY0020 2 None None None 16760635 Common - putative ABC transport ATP-binding protein STY1862 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 16759146 Common - putative symporter STY0171 79 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16762124 Common yhcQ p-hydroxybenzoic acid efflux subunit AaeA STY3546 148 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16760992 Common yeeA hypothetical protein STY2265 19 COG1289 COG1289, Predicted membrane protein Function unknown 16763310 Common - hypothetical protein STY4858 10 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 16762108 Common degQ serine endoprotease STY3528 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 16761624 Common hycG formate hydrogenlyase subunit 7 STY2969 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 16759078 Common - puatative sulfatase STY0098 70 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 16760077 Common holB DNA polymerase III subunit delta' STY1240 194 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 16759640 Common ybfF hypothetical protein STY0734 143 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 16759907 Common - putative prophage terminase small subunit STY1046 10 None None None 16761030 Common galF UTP--glucose-1-phosphate uridylyltransferase subunit GalF STY2308 228 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 16760448 Common manA mannose-6-phosphate isomerase STY1655 41 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 16759089 Common djlA Dna-J like membrane chaperone protein STY0109 69 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 16761201 Common - putative MR-MLE-family protein STY2500 112 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16760562 Common thrS threonyl-tRNA synthetase STY1778 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16762333 Common - hypothetical protein STY3765 141 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 16760712 Common - hypothetical protein STY1952 102 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 16760611 Common - hypothetical protein STY1835 16 COG2606 EbsC, Uncharacterized conserved protein Function unknown 16759015 Common bcfA fimbrial subunit STY0024 16 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16759909 Common - putative bacteriophage protein STY1048 20 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 16760064 Common rluC 23S rRNA pseudouridylate synthase C STY1227 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16759772 Common yliJ glutathione s-transferase family protein STY0895 92 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16759799 Common artQ arginine transporter permease subunit ArtQ STY0922 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 16763224 Common ytfJ hypothetical protein STY4763 18 COG3054 COG3054, Predicted transcriptional regulator General function prediction only 16760970 Common pduF propanediol diffusion facilitator STY2242 135 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 16761869 Common - hypothetical protein STY3247 194 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 16759839 Common ycaD putative MFS family transporter protein STY0966 111 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 16762908 Common malG maltose transporter permease STY4423 183 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 16759358 Common ddl D-alanyl-alanine synthetase A STY0412 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 16759080 Common yabF glutathione-regulated potassium-efflux system ancillary protein KefF STY0100 72 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 16762815 Common fic cell filamentation protein Fic STY4326 38 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 16760319 Common - putative transport protein (pseudogene) STY1508 48 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 16762178 Common yigI hypothetical protein STY3603 51 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 16760762 Common - putative bacteriophage protein STY2019 14 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 16760416 Common - conserved bacteriophage hypothetical protein STY1622 17 COG4387 COG4387, Mu-like prophage protein gp36 Function unknown 16760899 Common - D-cysteine desulfhydrase STY2161 72 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 16762161 Common tatA twin argininte translocase protein A STY3586 51 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 16762252 Common - terminase, endonuclease subunit STY3678 19 None None None 16761781 Common - dinucleoside polyphosphate hydrolase STY3145 115 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16761758 Common ygdE hypothetical protein STY3120 46 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 16762189 Common - possible exported protein STY3614 3 None None None 16763240 Common - hypothetical protein STY4779 11 None None None 16759745 Common - predicted mechanosensitive channel STY0865 130 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16760253 Common - putative ABC amino acid transporter permease STY1437 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 16761556 Common iroB putative glycosyltransferase STY2890 27 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 16759722 Common bioD dithiobiotin synthetase STY0830 160 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 16760277 Common - hypothetical protein STY1461 4 None None None 16761197 Common rcsB DNA-binding response regulator in two-component regulatory system with RcsC and YojN STY2495 170 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16763189 Common yjfI hypothetical protein STY4727 14 COG3789 COG3789, Uncharacterized protein conserved in bacteria Function unknown 16760857 Common cutC copper homeostasis protein CutC STY2115 58 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 16759170 Common yadI putative PTS system IIA component STY0196 23 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 16763208 Common rpsF 30S ribosomal protein S6 STY4747 189 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 16763245 Common - dihydroorotase STY4784 27 COG3964 COG3964, Predicted amidohydrolase General function prediction only 16763085 Common nucD2 putative lysozyme STY4620 45 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 16763079 Common - phage baseplate assembly protein STY4614 29 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 16763175 Common yjeF hypothetical protein STY4713 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 16759537 Common apeE outer membrane esterase STY0619 18 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 16761012 Common gnd 6-phosphogluconate dehydrogenase STY2290 188 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 16761365 Common - hypothetical protein STY2684 10 None None None 16762381 Common - possible integral membrane transport protein STY3820 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 16760441 Pathogen - hypothetical protein STY1648 1 None None None 16763054 Pathogen - hypothetical protein STY4587 1 None None None 16759666 Pathogen - hypothetical protein STY0770 1 None None None 16760862 Common flhA flagellar biosynthesis protein A STY2122 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 16762883 Common yrdA putative transferase STY4398 190 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 16761501 Common yfiC hypothetical protein STY2835 83 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 16759902 Common - putative prophage membrane protein STY1041 9 None None None 16760682 Common hyaE hydrogenase-1 operon protein HyaE STY1917 12 None None None 16759206 Common rpsB 30S ribosomal protein S2 STY0239 230 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 16759521 Common fimZ transcriptional regulator FimZ STY0596 209 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16762454 Common atpI F0F1 ATP synthase subunit I STY3906 12 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 16761541 Common - large repetitive protein STY2875 177 None None None 16760741 Common pphA serine/threonine protein phosphatase 1 STY1984 117 None None None 16761039 Common fcl GDP-fucose synthetase STY2320 224 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16762926 Common qor quinone oxidoreductase, NADPH-dependent STY4441 175 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 16759979 Common hpaB 4-hydroxyphenylacetate 3-monooxygenase STY1131 49 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 16761914 Common uxuB D-mannonate oxidoreductase STY3307 88 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 16760202 Common - hypothetical protein STY1377 42 COG3768 COG3768, Predicted membrane protein Function unknown 16761135 Common folE GTP cyclohydrolase I STY2427 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 16762996 Common - hypothetical protein STY4517 23 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 16761738 Common - hypothetical protein STY3097 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 16762812 Common yhfC hypothetical protein STY4323 57 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 16759528 Common - possible copper-binding protein STY0609 5 None None None 16762362 Common ydeW putative regulatory protein STY3797 69 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 16759739 Common - hypothetical protein STY0853 149 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16761586 Pathogen - hypothetical protein STY2929 1 None None None 16761445 Common pbpC penicillin-binding protein 1C STY2777 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 16761171 Common - bacteriophage tail fiber assembly protein (pseudogene) STY2468 7 None None None 16761312 Common fadJ multifunctional fatty acid oxidation complex subunit alpha STY2620 189 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 16760812 Common - hypothetical protein STY2068 3 None None None 16759372 Common sbcC exonuclease subunit SbcC STY0429 85 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 16759752 Common tnpA transposase for insertion sequence element is200 STY0874 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16761376 Common eutB ethanolamine ammonia-lyase heavy chain STY2695 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 16759846 Common - hypothetical protein STY0976 67 COG2323 COG2323, Predicted membrane protein Function unknown 16759445 Common tesB acyl-CoA thioesterase II STY0508 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 16762766 Common glgA glycogen synthase STY4275 131 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 16761326 Common - lipid A biosynthesis palmitoleoyl acyltransferase STY2639 101 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 16760628 Common - putative transcriptional regulator STY1855 13 COG0789 SoxR, Predicted transcriptional regulators Transcription 16761834 Common gcvP glycine dehydrogenase STY3209 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 16761269 Common - putative sugar phosphotransferase component II A STY2574 44 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 16761478 Common purL phosphoribosylformylglycinamidine synthase STY2812 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 16762292 Common rsD anti-RNA polymerase sigma 70 factor STY3720 24 COG3160 Rsd, Regulator of sigma D Transcription 16760251 Common - putative amino acid ABC transporter STY1435 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 16761395 Common - hypothetical protein STY2716 132 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 16762811 Common nirB nitrite reductase large subunit STY4322 205 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 16761558 Common iroD putative ferric enterochelin esterase STY2892 28 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 16762757 Common - putative oxidoreductase STY4266 167 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 16762262 Common - phage baseplate assembly protein STY3688 30 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 16761059 Common baeS signal transduction histidine-protein kinase BaeS STY2343 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16762758 Common - hypothetical protein STY4267 146 COG1741 COG1741, Pirin-related protein General function prediction only 16760362 Common - hypothetical protein STY1562 6 None None None 16761107 Common yehY putative permease transmembrane component STY2394 116 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 16761737 Common barA hybrid sensory histidine kinase BarA STY3096 226 COG4999 COG4999, Uncharacterized domain of BarA-like signal transduction histidine kinases Signal transduction mechanisms 16760303 Common narU nitrite extrusion protein STY1489 84 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 16761663 Common spaT unknown function STY3009 18 None None None 16762281 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase STY3709 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 16760649 Pathogen - hypothetical protein STY1876 1 None None None 16763248 Common - putative BglB-family transcriptional antiterminator STY4787 41 COG3711 BglG, Transcriptional antiterminator Transcription 16761455 Common iscA iron-sulfur cluster assembly protein STY2787 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 16761290 Common folC bifunctional folylpolyglutamate synthase/ dihydrofolate synthase STY2596 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 16762117 Common - possible GntR-family transcriptional regulator STY3538 103 COG1802 GntR, Transcriptional regulators Transcription 16759727 Common moaB molybdenum cofactor biosynthesis protein B STY0837 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 16762772 Common malT transcriptional regulator MalT STY4281 86 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 16759626 Common nagC N-acetylglucosamine repressor STY0720 169 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 16760922 Common fliO flagellar biosynthesis protein FliO STY2186 32 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 16760025 Common - hypothetical protein STY1185 139 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 16759005 Common dnaK molecular chaperone DnaK STY0012 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 16760065 Common maf Maf-like protein STY1228 194 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 16762419 Pathogen - hypothetical protein STY3864 1 None None None 16760580 Common celD DNA-binding transcriptional dual regulator STY1798 84 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16760861 Common flhE flagellar protein FlhE precursor STY2121 9 None None None 16759927 Pathogen - putative bacteriophage protein STY1066 1 None None None 16760161 Common - 23S rRNA pseudouridylate synthase B STY1331 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 16760204 Common tnpA transposase for insertion sequence element IS200 STY1379 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16759833 Common ycaJ recombination factor protein RarA STY0960 238 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 16763074 Pathogen sopE invasion-associated secreted protein. STY4609 3 None None None 16759454 Common ybaJ hypothetical protein STY0517 10 None None None 16762186 Common yigA hypothetical protein STY3611 41 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 16761821 Common lysS lysyl-tRNA synthetase STY3196 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 16760752 Common yjcS putative hydrolase STY2004 43 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 16759893 Common - putative bacteriophage protein STY1031 45 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 16761124 Common yohK predicted inner membrane protein STY2412 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 16761516 Common rluD 23S rRNA pseudouridine synthase D STY2851 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16759579 Common citG triphosphoribosyl-dephospho-CoA synthase STY0668 48 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 16761749 Common sdaB L-serine dehydratase 2 (L-serine deaminase 2) STY3110 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 16763337 Common - hypothetical protein STY4889 27 COG2879 COG2879, Uncharacterized small protein Function unknown 16760313 Common hdeB acid-resistance protein STY1501 5 None None None 16761074 Pathogen - hypothetical protein STY2359 1 None None None 16759669 Common gltA type II citrate synthase STY0773 194 COG0372 GltA, Citrate synthase Energy production and conversion 16760838 Common pykA pyruvate kinase STY2096 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 16759873 Common int integrase STY1011 95 COG0582 XerC, Integrase DNA replication, recombination, and repair 16761523 Common aroF phospho-2-dehydro-3-deoxyheptonate aldolase STY2857 108 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 16760435 Common - alternative bacteriophage tail fiber C-terminus STY1641 19 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 16763333 Common mrr mrr restriction system protein STY4885 41 COG1715 Mrr, Restriction endonuclease Defense mechanisms 16760415 Common - hypothetical protein STY1621 6 None None None 16761678 Common - hypothetical protein STY3026 21 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 16762051 Common infB translation initiation factor IF-2 STY3467 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 16761829 Common - putative global regulator STY3204 97 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 16763302 Common - DEAD-box helicase-related protein STY4850 111 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 16763221 Common ytfH hypothetical protein STY4760 141 COG1733 COG1733, Predicted transcriptional regulators Transcription 16759215 Common ompH periplasmic chaperone STY0248 60 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 16760830 Common opdB protease 2 STY2085 101 COG1770 PtrB, Protease II Amino acid transport and metabolism 16762411 Common yihU putative oxidoreductase STY3855 170 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 16760757 Common - putative bacteriophage tail protein STY2014 10 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 16761740 Common ygcY probable glucarate dehydratase 2 STY3099 50 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 16762750 Common - hypothetical protein STY4259 6 None None None 16761427 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein STY2751 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 16761693 Common - possible decarboxylase STY3046 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 16759589 Common cspE cold shock protein E STY0678 180 COG1278 CspC, Cold shock proteins Transcription 16762024 Common - PTS-transport family phosphoryl transfer protein STY3438 110 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 16760575 Common cedA cell division modulator STY1792 6 None None None 16761087 Common - putative gntR-family transcriptional regulator STY2374 123 COG2188 PhnF, Transcriptional regulators Transcription 16763030 Common - hypothetical protein STY4561 6 COG1715 Mrr, Restriction endonuclease Defense mechanisms 16760006 Common - putative membrane transporter STY1165 74 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 16760408 Common - hypothetical protein STY1614 18 None None None 16759267 Common - hypothetical protein STY0304 47 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 16760171 Common - hypothetical protein STY1342 21 COG3771 COG3771, Predicted membrane protein Function unknown 16759990 Common cbpA curved DNA-binding protein CbpA STY1148 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 16761150 Pathogen - hypothetical protein STY2445 1 None None None 16761424 Common - hypothetical protein STY2748 4 None None None 16762093 Common gltD glutamate synthase subunit beta STY3511 213 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 16759495 Common hyi hydroxypyruvate isomerase STY0566 84 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 16762723 Common - hypothetical protein STY4230 37 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16760019 Common csgD DNA-binding transcriptional activator in two-component regulatory system STY1179 143 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16762975 Common - predicted metal dependent hydrolase STY4492 66 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 16760552 Common btuD vitamin B12-transporter ATPase STY1768 249 COG4138 BtuD, ABC-type cobalamin transport system, ATPase component Coenzyme metabolism 16762982 Common fumB fumarate hydratase class I STY4499 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 16763047 Common - hypothetical protein STY4579 23 None None None 16762438 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B STY3887 98 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 16763126 Common - putative DNA helicase STY4664 27 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 16762218 Common - putative membrane transport protein STY3643 62 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 16760771 Common - putative bacteriophage protein STY2028 7 None None None 16761876 Common - hypothetical protein STY3254 60 COG0762 COG0762, Predicted integral membrane protein Function unknown 16762474 Common pstA phosphate transporter permease subunit STY3928 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 16760618 Common tnpA transposase for insertion sequence element IS200 STY1844 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16761417 Common purM phosphoribosylaminoimidazole synthetase STY2740 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 16761050 Common dcd deoxycytidine triphosphate deaminase STY2334 154 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 16761099 Common - putative lipoprotein STY2386 8 COG4808 COG4808, Uncharacterized protein conserved in bacteria Function unknown 16762502 Common yhjA probable cytochrome c peroxidase STY3958 95 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 16761210 Common glpA sn-glycerol-3-phosphate dehydrogenase subunit A STY2513 163 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 16762850 Common rplP 50S ribosomal protein L16 STY4365 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 16761255 Common lrhA NADH dehydrogenase operon transcriptional regulator STY2560 119 COG0583 LysR, Transcriptional regulator Transcription 16760587 Common - periplasmic protein STY1805 21 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 16759375 Common phoR phosphate regulon sensor protein STY0433 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 16761856 Common - possible ABC-transport protein, ATP-binding component STY3232 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 16762324 Common yijP hypothetical protein STY3755 51 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 16759381 Common yajB acyl carrier protein phosphodiesterase STY0441 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 16762382 Common - hypothetical protein STY3821 10 None None None 16760570 Common - hypothetical protein STY1787 71 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 16761804 Pathogen - hypothetical protein STY3174 1 None None None 16760606 Common - putative oxidoreductase STY1828 191 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 16760097 Common potD spermidine/putrescine ABC transporter periplasmic substrate-binding protein STY1262 141 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 16760002 Common putP sodium/proline symporter (proline permease) STY1160 183 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 16761297 Common - hypothetical protein STY2603 112 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762136 Common - putative sulfite oxidase subunit YedY STY3557 124 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 16760737 Common - hypothetical protein STY1980 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 16761274 Common - putative glutathione-S transferase STY2579 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16761607 Common mltB membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan STY2952 107 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 16763042 Pathogen - hypothetical protein STY4574 3 None None None 16761786 Common ygeD hypothetical protein STY3152 71 None None None 16762874 Common sun 16S rRNA methyltransferase B STY4389 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 16762699 Common treF trehalase STY4200 29 COG1626 TreA, Neutral trehalase Carbohydrate transport and metabolism 16761219 Common - competence damage-inducible protein A STY2523 138 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 16761405 Common nlpB lipoprotein STY2726 21 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 16762675 Common dppD dipeptide transporter ATP-binding subunit STY4171 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 16761772 Common recC exonuclease V subunit gamma STY3134 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 16760388 Pathogen - hypothetical protein STY1593 1 None None None 16762317 Common udhA soluble pyridine nucleotide transhydrogenase STY3748 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 16761090 Common yohN hypothetical protein STY2377 9 COG5455 COG5455, Predicted integral membrane protein Function unknown 16759994 Common scsD secreted protein, suppressor for copper-sensitivity D STY1152 74 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16761509 Common - putative acyl-CoA synthetase STY2844 149 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 16759290 Common safC outer-membrane fimbrial usher protein STY0336 36 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16762830 Common fkpA FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) STY4345 132 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 16760132 Common hns global DNA-binding transcriptional dual regulator H-NS STY1299 26 COG2916 Hns, DNA-binding protein H-NS General function prediction only 16763129 Common - hypothetical protein STY4667 23 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 16759511 Common ppiB peptidyl-prolyl cis-trans isomerase B (rotamase B) STY0584 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 16760730 Common - hypothetical protein STY1971 8 None None None 16760399 Common - hypothetical protein STY1605 3 None None None 16761040 Common gmd GDP-mannose 4,6-dehydratase STY2321 229 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 161501922 Common - hypothetical protein STY3178 6 None None None 16762531 Common uhpB sensory histidine kinase UhpB STY3993 143 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 16763108 Common - phage integrase STY4645 206 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16759646 Common kdpD sensor protein KdpD STY0744 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 16761494 Common lepB lsignal peptidase I STY2828 199 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 16760477 Common nemA N-ethylmaleimide reductase, FMN-linked STY1686 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 16761918 Common - putative glutathione S-transferase YghU STY3311 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16759851 Common rpsA 30S ribosomal protein S1 STY0981 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 16763313 Common - hypothetical protein STY4861 22 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 16759504 Common fdrA membrane protein FdrA STY0577 82 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 16760875 Pathogen - hypothetical protein STY2135 1 None None None 16762514 Common hslS heat shock chaperone IbpB STY3970 66 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 16759641 Common seqA replication initiation regulator SeqA STY0735 23 COG3057 SeqA, Negative regulator of replication initiationR DNA replication, recombination, and repair 16761691 Common - DeoR-family trancriptional regulator STY3044 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16762336 Common metB cystathionine gamma-synthase STY3769 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 16762287 Common hupA transcriptional regulator HU subunit alpha STY3715 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 16762642 Common - 2,3-diketo-L-gulonate reductase STY4130 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 16760401 Common - hypothetical protein STY1607 16 COG3081 COG3081, Nucleoid-associated protein General function prediction only 16763348 Common - ferric iron reductase involved in ferric hydroximate transport STY4903 16 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 16762209 Common wecC UDP-N-acetyl-D-mannosamine dehydrogenase STY3634 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 16762631 Common - putative transcriptional regulator STY4118 102 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 16761561 Pathogen - hypothetical protein STY2895 1 None None None 16763096 Pathogen - hypothetical protein STY4631 4 None None None 16759046 Common citB transcriptional regulatory protein citb STY0061 178 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 16759673 Common sdhA succinate dehydrogenase flavoprotein subunit STY0777 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 16760515 Pathogen ssaE putative secretion system protein STY1724 1 None None None 16761091 Common stcD hypothetical protein STY2378 5 None None None 16763250 Common relE hypothetical protein STY4789 25 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 16761704 Common ygbE hypothetical protein STY3057 10 None None None 16762644 Common - putative electron-transport protein STY4132 144 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 16760179 Common - hypothetical protein STY1351 9 COG4950 COG4950, Uncharacterized protein conserved in bacteria Function unknown 16761209 Common glpT sn-glycerol-3-phosphate transporter STY2512 86 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16762593 Common waaJ lipopolysaccharide 1,2-glucosyltransferase STY4078 31 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 16762408 Common yihX phosphatase STY3852 33 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 16761176 Common dsbE1 thiol:disulfide interchange protein STY2474 117 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16762633 Common yiaR putative L-xylulose 5-phosphate 3-epimerase STY4120 23 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 16761348 Common - cell division protein ZipA STY2664 44 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 16761341 Common xapB xanthosine permease STY2657 29 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16762363 Common ydeV autoinducer-2 (AI-2) kinase STY3798 177 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16762618 Common sapB putative autotransporter STY4105 87 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 16760988 Common pduV putative propanediol utilization protein PduV STY2261 19 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 16762401 Common yiiF putative CopG-family DNA-binding protein STY3845 12 COG3905 COG3905, Predicted transcriptional regulator Transcription 16762839 Common yheA bacterioferritin-associated ferredoxin STY4354 25 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 16763340 Common yjjA hypothetical protein STY4895 15 None None None 16759476 Common ybaR copper transporter STY0544 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 16759297 Common tsaC outer membrane fimbrial user protein STY0347 9 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16761049 Common asmA putative assembly protein STY2333 41 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 16760236 Common tnpA transposase for insertion sequence element IS200 STY1418 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16761863 Common - hypothetical protein STY3241 3 None None None 16760328 Common - putative secreted hydrolase STY1522 48 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 16759519 Common fimH FimH protein precursor STY0594 5 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16762561 Common yicJ putative transporter STY4043 82 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16760966 Common cbiD cobalt-precorrin-6A synthase STY2237 94 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 16759654 Common - hypothetical protein STY0752 101 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 16760244 Common - hypothetical protein STY1426 52 COG3791 COG3791, Uncharacterized conserved protein Function unknown 16762955 Common - hypothetical protein STY4472 41 COG3162 COG3162, Predicted membrane protein Function unknown 16760440 Common rstA DNA-binding response regulator in two-component regulatory system with RstB STY1647 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16759251 Common - hypothetical protein STY0286 7 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 16759422 Common cyoB cytochrome o ubiquinol oxidase subunit I STY0484 165 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 16761604 Common recX recombination regulator RecX STY2949 68 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 16760484 Common ydhB putative DNA-binding transcriptional regulator STY1693 162 COG0583 LysR, Transcriptional regulator Transcription 16763284 Common - protein kinase STY4823 142 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 16762649 Common xylA xylose isomerase STY4137 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 16762089 Common - isoprenoid biosynthesis protein with amidotransferase-like domain STY3506 41 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 16760116 Common chaB cation transport regulator STY1282 22 COG4572 ChaB, Putative cation transport regulator General function prediction only 16761997 Common - probable membrane transport protein STY3405 111 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 16760157 Common trpD bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase STY1327 230 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 16761725 Common pyrG CTP synthetase STY3082 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 16759279 Common - Rhs-family protein STY0319 57 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 16759971 Common sigD cell invasion protein STY1121 4 None None None 16760140 Common - possible membrane transport protein STY1310 118 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 16762301 Common rplL 50S ribosomal protein L7/L12 STY3733 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 16762842 Common rpsJ 30S ribosomal protein S10 STY4357 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 16759160 Common - putative transcriptional regulator STY0186 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16763273 Pathogen - hypothetical protein STY4811 1 None None None 16762713 Pathogen - hypothetical protein STY4216 1 None None None 16760392 Common - hypothetical protein STY1597 3 None None None 16759281 Common - Rhs-family protein STY0321 71 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 16760145 Common yciA predicted hydrolase STY1315 134 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 16762210 Common wecB UDP-N-acetyl-D-glucosamine 2-epimerase STY3635 157 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 16759107 Common leuB 3-isopropylmalate dehydrogenase STY0131 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 16763318 Common - probable aspartate racemase STY4866 77 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 16763135 Common cII transcriptional regulatory protein STY4673 24 COG3423 Nlp, Predicted transcriptional regulator Transcription 16760986 Common pduT putative propanediol utilization protein PduT STY2259 36 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 16762935 Common uvrA excinuclease ABC subunit A STY4450 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 16762788 Common yhgE hypothetical protein STY4297 20 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16760336 Pathogen - hypothetical protein STY1533 3 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 16762818 Common crp cAMP-regulatory protein STY4331 170 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16759028 Common - hypothetical protein STY0041 8 None None None 16762969 Common phnO aminoalkylphosphonic acid N-acetyltransferase STY4486 51 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 16761200 Common gyrA DNA gyrase subunit A STY2499 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 16760038 Common dinI DNA damage-inducible protein I STY1200 11 None None None 16759712 Common hutI imidazolonepropionase STY0820 101 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 16759270 Pathogen - hypothetical protein STY0307 4 None None None 16759429 Common clpX ATP-dependent protease ATP-binding subunit STY0491 229 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 16761283 Common - hypothetical protein STY2588 16 COG3457 COG3457, Predicted amino acid racemase Amino acid transport and metabolism 16761117 Common - salicylate hydroxylase STY2405 71 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 16759701 Common galE UDP-galactose-4-epimerase STY0809 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 16762332 Common - putative serine hydroxymethyltransferase STY3764 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 16762748 Common ugpC glycerol-3-phosphate transporter ATP-binding subunit STY4257 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 16760023 Common - hypothetical protein STY1183 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16761688 Common - hypothetical protein STY3039 108 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16760357 Common rspB starvation sensing protein RspB STY1555 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 16763261 Common pyrB aspartate carbamoyltransferase catalytic subunit STY4800 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 161501932 Common znuA high-affinity zinc transporter periplasmic component STY2099 170 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 16763367 Common lplA lipoate-protein ligase A STY4923 73 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 16762741 Common livM leucine/isoleucine/valine transporter permease subunit STY4250 138 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 16759785 Common rimK ribosomal protein S6 modification protein STY0908 157 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 16759048 Common oadB oxaloacetate decarboxylase beta chain STY0063 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 16761975 Common glnE bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase STY3380 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 16763086 Common nucE2 possible secretion protein STY4621 5 None None None 16760450 Common add adenosine deaminase STY1658 106 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 16760494 Pathogen ssaP putative type III secretion protein STY1703 1 None None None 16759245 Common yafE putative methyltransferase STY0280 213 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 16760729 Common - hypothetical protein STY1970 5 None None None 16760592 Common argD bifunctional succinylornithine transaminase/acetylornithine transaminase STY1811 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 16762447 Common yieN hypothetical protein STY3899 81 COG0714 COG0714, MoxR-like ATPases General function prediction only 16759758 Common - hypothetical protein STY0880 11 None None None 16760907 Common amyA cytoplasmic alpha-amylase STY2171 49 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 16762192 Pathogen - hypothetical protein STY3617 1 None None None 16759947 Common rmf ribosome modulation factor (protein E) STY1087 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 16759092 Common polB DNA polymerase II STY0112 64 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 16759781 Common - hypothetical protein STY0904 8 None None None 16759583 Common citD citrate lyase subunit gamma STY0672 25 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 16761993 Common - hypothetical protein STY3401 39 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 16762856 Common rpsN 30S ribosomal protein S14 STY4371 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 16760355 Common - putative D-mannonate oxidoreductase STY1553 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 16760087 Common - hypothetical protein STY1252 26 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 16761742 Common - flavodoxin STY3102 63 COG0716 FldA, Flavodoxins Energy production and conversion 16761366 Common - hypothetical protein STY2685 12 None None None 16762230 Common ilvG acetolactate synthase 2 catalytic subunit STY3656 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 16760940 Common umuD DNA polymerase V subunit UmuD STY2206 152 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 16759793 Pathogen - hypothetical protein STY0916 1 None None None 16763069 Common - hypothetical protein STY4603 37 COG5283 COG5283, Phage-related tail protein Function unknown 16760120 Common narX nitrate/nitrite sensor protein NarX STY1286 143 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 16759867 Common aspC aromatic amino acid aminotransferase STY1000 77 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 16760127 Pathogen - hypothetical protein STY1293 1 None None None 16761447 Common sseA 3-mercaptopyruvate sulfurtransferase STY2779 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 16762150 Common yigZ hypothetical protein STY3575 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 16762014 Common tdcB threonine dehydratase STY3427 213 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 16762704 Pathogen - hypothetical protein STY4207 1 None None None 16762223 Common ilvY DNA-binding transcriptional regulator IlvY STY3649 190 COG0583 LysR, Transcriptional regulator Transcription 16762254 Common - probable phage tail protein STY3680 26 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 16761531 Common corE hypothetical protein STY2865 55 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 16761178 Common ccmE1 cytochrome c-type biogenesis protein CcmE STY2476 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 16761346 Common ypeB hypothetical protein STY2662 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 16762897 Common - deoR family regulatory protein STY4412 117 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16759388 Common - putative deoR-family transcriptional regulator STY0448 103 COG2378 COG2378, Predicted transcriptional regulator Transcription 16760897 Common - putative amino-acid ABC transporter ATP-binding protein YecC STY2159 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 16761489 Common acpS 4'-phosphopantetheinyl transferase STY2823 161 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 16761374 Common eutL ethanolamine utilization protein EutL STY2693 20 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 16760811 Common - hypothetical protein STY2067 4 None None None 16759455 Common acrB acriflavin resistance protein B STY0519 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 16760977 Common pduH PduH protein STY2249 10 None None None 16759186 Common sfsA sugar fermentation stimulation protein A STY0212 103 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 16762546 Common - putative PTS system protein STY4014 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 16762060 Common - RNA-binding protein YhbY STY3476 98 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 16760518 Common spiC putative pathogenicity island 2 secreted effector protein STY1727 2 None None None 16759462 Common apt adenine phosphoribosyltransferase STY0527 190 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 16760825 Common - putative cation transporter STY2080 26 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 16760341 Common - sugar efflux transporter STY1538 155 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16761014 Common rfbK phosphomannomutase STY2292 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 16762491 Common - putative LysR-family transcriptioanl regulator STY3944 188 COG0583 LysR, Transcriptional regulator Transcription 16761411 Common - hypothetical protein STY2734 138 COG0628 PerM, Predicted permease General function prediction only 16762523 Pathogen ivbL ilvB operon leader peptide STY3985 1 None None None 16759112 Common ilvH acetolactate synthase 3 regulatory subunit STY0136 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 16762780 Common yhgG hypothetical protein STY4289 9 COG1378 COG1378, Predicted transcriptional regulators Transcription 16761275 Common - hypothetical protein STY2580 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 16762990 Common - hypothetical protein STY4511 10 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 16760517 Common spiA putative outer membrane secretory protein STY1726 124 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 16761735 Common relA GDP/GTP pyrophosphokinase STY3094 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 16760809 Common - putative cro repressor STY2065 8 COG1396 HipB, Predicted transcriptional regulators Transcription 16761325 Common - hypothetical protein STY2638 3 None None None 16762330 Common - putative GntR-family regulatory protein STY3762 190 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 16762600 Common rfaD ADP-L-glycero-D-mannoheptose-6-epimerase STY4085 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16761884 Common - hypothetical protein STY3263 25 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 16761727 Common steB outer membrane usher protein STY3086 31 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 16759497 Common - probable metabolite transport protein STY0568 149 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16761199 Common tnpA transposase for insertion sequence element IS200 STY2497 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760685 Common appB probable cytochrome oxidase subunit II STY1921 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 16760381 Common - multidrug efflux system protein MdtJ STY1585 142 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 16759209 Common frr ribosome recycling factor STY0242 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 16761463 Common asrB anaerobic sulfite reductase subunit B STY2795 108 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 16759847 Common serC phosphoserine aminotransferase STY0977 114 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 16761404 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase STY2725 204 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 16763059 Common - hypothetical protein STY4592 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 16761191 Common yojI multidrug transporter membrane component/ATP-binding component STY2489 248 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 16759200 Common htrA serine endoprotease STY0231 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 16762828 Common slyD FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) STY4343 125 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 16760370 Common - putative ABC transporter membrane protein STY1572 129 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 16762297 Common thiG thiazole synthase STY3725 167 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 16760348 Common - hypothetical protein STY1545 10 COG3111 COG3111, Uncharacterized conserved protein Function unknown 16759331 Pathogen - probable secreted protein STY0382 1 None None None 16762573 Common - putative regulatory protein STY4058 78 COG0583 LysR, Transcriptional regulator Transcription 16761132 Common mglB D-galactose-binding periplasmic protein precursor STY2424 90 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 16763142 Common int bacteriophage integrase STY4680 99 COG0582 XerC, Integrase DNA replication, recombination, and repair 16761468 Common glyA serine hydroxymethyltransferase STY2802 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 16759023 Pathogen - hypothetical protein STY0035 2 COG3710 CadC, DNA-binding winged-HTH domains Transcription 16760051 Common flgC flagellar basal body rod protein FlgC STY1214 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 16761626 Common hycE formate hydrogenlyase subunit 5 STY2971 197 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 16760667 Common - putative transcriptional regulator STY1899 34 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 16762322 Common argE acetylornithine deacetylase STY3753 175 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 16761612 Common srlM DNA-binding transcriptional activator of glucitol operon STY2957 12 COG4578 GutM, Glucitol operon activator Transcription 16759880 Pathogen gam host-nuclease inhibitor protein STY1018 4 None None None 16762122 Common - hypothetical protein STY3544 9 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 16759392 Common yajI hypothetical protein STY0452 9 None None None 16759710 Common ybhE 6-phosphogluconolactonase STY0818 52 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 16761956 Common parE DNA topoisomerase IV subunit B STY3359 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 16761212 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C STY2515 183 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 16762651 Pathogen yiaB hypothetical protein STY4139 2 COG4682 COG4682, Predicted membrane protein Function unknown 16762920 Pathogen - hypothetical protein STY4435 1 None None None 16763316 Pathogen - hypothetical protein STY4864 1 None None None 16761568 Common - hypothetical protein STY2906 67 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 16760901 Common fliZ protein FliZ STY2163 9 None None None 16762468 Common stgD probable fimbrial protein STY3922 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760785 Pathogen - hypothetical protein STY2042 1 None None None 16761202 Common ubiG 3-demethylubiquinone-9 3-methyltransferase STY2505 167 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 16761812 Common - endonuclease fragment STY3184 5 None None None 16760886 Pathogen - hypothetical protein STY2147 1 None None None 16760953 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase STY2219 119 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 16762728 Common zntA zinc/cadmium/mercury/lead-transporting ATPase STY4235 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 161501953 Common yacA SecA regulator SecM STY0155 11 None None None 16760261 Common aac aminoglycoside 6'-N-acetyltransferase STY1445 18 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 16761262 Common ackA acetate kinase STY2567 162 COG0282 ackA, Acetate kinase Energy production and conversion 16763191 Common yjfL hypothetical protein STY4730 29 COG3766 COG3766, Predicted membrane protein Function unknown 16760507 Pathogen sseF putative pathogenicity island effector protein STY1716 1 None None None 16760969 Common pocR pdu/cob regulatory protein PocR STY2241 135 COG4936 PocR, Predicted sensor domain Signal transduction mechanisms / Transcription 16759580 Common citX 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase STY0669 24 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 16763178 Common mutL DNA mismatch repair protein STY4716 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 16760092 Common - outer membrane-specific lipoprotein transporter subunit LolC STY1257 153 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 16759697 Common gpmA phosphoglyceromutase STY0804 163 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 16762906 Common - putative lipoprotein STY4421 23 None None None 16761147 Common fruB fructose-specific PTS IIA/HPr components STY2442 117 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 16760918 Common fliK flagellar hook-length control protein STY2182 31 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 16762626 Common selA selenocysteine synthase STY4113 73 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 16762544 Common - putative secreted protein STY4010 5 None None None 16763233 Common - putative metallo-dependent hydrolase STY4772 30 COG3964 COG3964, Predicted amidohydrolase General function prediction only 16759420 Common cyoD cytochrome o ubiquinol oxidase subunit IV STY0482 61 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 16759366 Common aroL shikimate kinase II STY0421 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 16763242 Common - hypothetical protein STY4781 11 None None None 16760637 Common - putative inner membrane transport protein STY1864 213 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16762988 Common - hypothetical protein STY4509 22 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 16759073 Common - putative lipoprotein STY0091 10 None None None 16760072 Common acpP acyl carrier protein STY1235 182 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16760337 Common - hypothetical protein STY1534 56 COG3781 COG3781, Predicted membrane protein Function unknown 16759148 Common pdhR transcriptional regulator PdhR STY0174 150 COG2186 FadR, Transcriptional regulators Transcription 16760768 Common - putative bacteriophage protein STY2025 7 None None None 16762163 Common yigP hypothetical protein STY3588 33 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 16763362 Common deoC deoxyribose-phosphate aldolase STY4918 137 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 16759934 Common - hypothetical protein STY1073 8 None None None 16760272 Common tehB tellurite resistance protein TehB STY1456 73 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 16759770 Common bssR biofilm formation regulatory protein BssR STY0893 6 None None None 16762663 Common yiaD predicted outer membrane lipoprotein STY4157 170 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 16762567 Common trmH tRNA guanosine-2'-O-methyltransferase STY4049 201 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 16762825 Common yheR glutathione-regulated potassium-efflux system ancillary protein KefG STY4340 63 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 16763210 Common rpsR 30S ribosomal protein S18 STY4749 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 161501915 Common argG argininosuccinate synthase STY3470 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 16763061 Pathogen - hypothetical protein STY4594 3 None None None 16761660 Common sipD pathogenicity island 1 effector protein STY3006 5 None None None 16759318 Pathogen - probable secreted protein STY0368 1 None None None 16759813 Common ybjX putative virK protein STY0936 21 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 16761944 Pathogen - hypothetical protein STY3343 2 None None None 16760698 Common - hypothetical protein STY1937 19 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 16762174 Common rhtB homoserine/homoserine lactone efflux protein STY3599 105 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 16760548 Common - hypothetical protein STY1764 6 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 16761580 Common - hypothetical protein STY2919 2 None None None 16761025 Common rfbI CDP-6-deoxy-delta-3,4-glucoseen reductase STY2303 144 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 16759327 Pathogen - possible transmembrane regulator STY0377 4 COG3710 CadC, DNA-binding winged-HTH domains Transcription 16759535 Common pheP phenylalanine transporter STY0617 171 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 16759345 Common prpR propionate catabolism operon regulatory protein STY0399 170 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 16760654 Pathogen pagD putative outer membrane virulence protein STY1880a 1 None None None 16760795 Common - hypothetical protein STY2052 11 None None None 16761068 Pathogen - hypothetical protein STY2352 2 None None None 16759818 Common clpA ATP-dependent Clp protease ATP-binding subunit STY0943 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 16760470 Common - hypothetical protein STY1679 9 None None None 16759525 Common - hypothetical protein STY0605 5 None None None 16762731 Common - hypothetical protein STY4238 15 COG3776 COG3776, Predicted membrane protein Function unknown 16759607 Common leuS leucyl-tRNA synthetase STY0699 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16762066 Common rplU 50S ribosomal protein L21 STY3483 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 16761089 Common - hydroxyethylthiazole kinase STY2376 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 16759155 Common acnB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase STY0181 209 COG1049 AcnB, Aconitase B Energy production and conversion 16761065 Pathogen - hypothetical protein STY2349 4 None None None 16763028 Common - hypothetical protein STY4559 44 None None None 16759914 Pathogen - putative bacteriophage protein STY1053 2 None None None 16759803 Common - hypothetical protein STY0926 96 COG0393 COG0393, Uncharacterized conserved protein Function unknown 16759860 Common smtA putative metallothionein SmtA STY0993 77 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 16762881 Common aroE shikimate 5-dehydrogenase STY4396 216 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 16761653 Common iagA invasion protein regulator STY2999 75 COG3710 CadC, DNA-binding winged-HTH domains Transcription 16761355 Common ptsJ putative transcriptional regulator STY2674 184 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 16761788 Common tnpA transposase for insertion sequence element IS200 STY3154 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 161501911 Common yiiM hypothetical protein STY3815 77 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 16759824 Common acT hypothetical transcriptional activator STY0950 135 COG0583 LysR, Transcriptional regulator Transcription 16761318 Common gtrA2 bactoprenol-linked glucose transferase STY2627a 7 COG2246 COG2246, Predicted membrane protein Function unknown 16762343 Common hslV ATP-dependent protease peptidase subunit STY3778 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 16762384 Common rhaR L-rhamnose operon transcriptional activator STY3824 109 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16759630 Common glnS glutaminyl-tRNA synthetase STY0724 241 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 16760218 Common - invasin-like protein STY1395 15 None None None 16761947 Pathogen - hypothetical protein STY3347 1 None None None 16762146 Common - hypothetical protein STY3568 176 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 16760743 Common - hypothetical protein STY1988 6 COG5562 COG5562, Phage envelope protein General function prediction only 16761295 Common pdxB erythronate-4-phosphate dehydrogenase STY2601 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 16763299 Common - putative gerE-family regulatory protein STY4843 15 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16759659 Pathogen - hypothetical protein STY0757 1 None None None 16761952 Common - possible exported protein STY3353 26 COG3111 COG3111, Uncharacterized conserved protein Function unknown 16760464 Common tyrS tyrosyl-tRNA synthetase STY1673 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16761224 Common pmrF undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase STY2528 179 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 161501934 Common - hypothetical protein STY1941 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 16759967 Common tnpA transposase for insertion sequence element is200 STY1114 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16763149 Common fxsA FxsA STY4687 36 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 16760848 Common ruvC Holliday junction resolvase STY2106 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 16760184 Common sapD peptide transport system ATP-binding protein SapD STY1356 249 COG4170 SapD, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 16762806 Common trpS tryptophanyl-tRNA synthetase STY4315 234 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16762283 Common hydG transcriptional regulatory protein ZraR STY3711 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 16762049 Common truB tRNA pseudouridine synthase B STY3465 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 16761796 Common kduI 5-keto-4-deoxyuronate isomerase STY3163 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 16761244 Common nuoK NADH dehydrogenase subunit K STY2549 68 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 16760520 Common ssrB putative two-component response regulator STY1729 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16760102 Common pepT peptidase T STY1267 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 16762131 Common mreD rod shape-determining protein MreD STY3552 50 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 16760807 Common - hypothetical protein STY2063 8 None None None 16759400 Common ispA geranyltranstransferase STY0462 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 16760720 Common manY phosphotransferase enzyme II, C component STY1960 37 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 16759777 Common - hypothetical protein STY0900 76 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16762338 Common - hypothetical protein STY3773 18 None None None 16761140 Common cirA ferric iron-catecholate outer membrane transporter STY2434 132 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 16760501 Common - putative pathogenicity island protein STY1710 4 None None None 16759685 Common tolR colicin uptake protein TolR STY0792 107 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 16760214 Pathogen - putative lipoprotein STY1391 1 None None None 16761520 Common pheA bifunctional chorismate mutase/prephenate dehydratase STY2854 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 16760927 Common dsrB hypothetical protein STY2191 10 None None None 16761850 Common fba fructose-bisphosphate aldolase STY3226 174 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 16762359 Common ydeZ putative ABC transporter, membrane component STY3794 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 16761018 Common rfbV putative glycosyltransferase STY2296 69 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16759593 Common ybeF putative DNA-binding transcriptional regulator STY0684 105 COG0583 LysR, Transcriptional regulator Transcription 16760675 Common - predicted inner membrane protein STY1908 10 None None None 16763211 Common rplI 50S ribosomal protein L9 STY4750 187 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 16759301 Common - possible outer membrane adhesin STY0351 29 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16758994 Pathogen thrL thr operon leader peptide STY0001 1 None None None 16761338 Common yfeD hypothetical protein STY2653 6 None None None 16759801 Common artP arginine transporter ATP-binding subunit STY0924 249 COG4161 ArtP, ABC-type arginine transport system, ATPase component Amino acid transport and metabolism 16761897 Pathogen - hypothetical protein STY3287 4 None None None 16759542 Common - hypothetical protein STY0625 6 None None None 16761832 Common bglA 6-phospho-beta-glucosidase STY3207 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 16761231 Common menE O-succinylbenzoic acid--CoA ligase STY2535 212 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16761238 Common - hypothetical protein STY2543 74 COG2153 ElaA, Predicted acyltransferase General function prediction only 16760725 Common ftsI2 penicillin-binding protein STY1965 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 16763072 Common - probable major tail tube protein STY4606 29 COG3498 COG3498, Phage tail tube protein FII General function prediction only 16762190 Pathogen - hypothetical protein STY3615 1 None None None 16763166 Common yjeA lysyl-tRNA synthetase STY4704 220 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 16762040 Common - hypothetical protein STY3456 32 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 16760569 Common - hypothetical protein STY1786 7 None None None 16762390 Common - putative DNA-binding protein STY3832 81 COG1396 HipB, Predicted transcriptional regulators Transcription 16762942 Common - large repetitive protein STY4459 97 None None None 16761096 Common mrp putative ATPase STY2383 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 16760802 Common - hypothetical protein STY2058 2 None None None 16762912 Common lamB maltoporin STY4427 27 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 16761591 Common proW glycine betaine transporter membrane protein STY2936 209 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 16759220 Common rnhB ribonuclease HII STY0253 238 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 16762421 Common - hypothetical protein STY3866 8 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 16759095 Pathogen - hypothetical protein STY0117 1 None None None 16760280 Pathogen - hypothetical protein STY1464 1 None None None 16762480 Common yieE hypothetical protein STY3934 8 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 16762718 Common - putative HlyD family secretion protein STY4223 131 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16759406 Common phnS probable periplasmic binding component of 2-aminoethylphosphonate transporter STY0468 74 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 16762031 Common - possible exported protein STY3447 40 COG3107 LppC, Putative lipoprotein General function prediction only 16759087 Common surA peptidyl-prolyl cis-trans isomerase SurA STY0107 160 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 16761157 Common yejB putative binding-protein-dependent transporter STY2453 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 16759415 Common - hypothetical protein STY0477 82 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 16759191 Common fhuD iron-hydroxamate transporter substrate-binding subunit STY0220 40 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 16760545 Common ppsA phosphoenolpyruvate synthase STY1761 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 16760429 Common - putative bacteriophage baseplate assembly protein STY1635 34 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 16760852 Common yecD hypothetical protein STY2110 125 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 16761792 Common lysR DNA-binding transcriptional regulator LysR STY3158 176 COG0583 LysR, Transcriptional regulator Transcription 16761182 Common ccmA1 heme exporter protein A1 STY2480 134 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 16762013 Common tdcD propionate/acetate kinase STY3424 161 COG0282 ackA, Acetate kinase Energy production and conversion 16761635 Common hypE hydrogenase isoenzyme formation protein HypE STY2980 129 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 16761159 Common yejF putative ABC-transporter ATP-binding protein STY2455 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 16762235 Common - hypothetical protein STY3661 6 None None None 16759129 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase STY0154 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 16762029 Common gatR galactitol utilization operon repressor STY3445 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16760403 Common - hypothetical protein STY1609 11 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16759142 Common nadC quinolinate phosphoribosyltransferase STY0167 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 16759149 Common aceE pyruvate dehydrogenase subunit E1 STY0175 148 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 16762863 Common secY preprotein translocase subunit SecY STY4378 224 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 16759235 Common yaeB hypothetical protein STY0270 95 COG1720 COG1720, Uncharacterized conserved protein Function unknown 16762008 Common - hypothetical protein STY3416 98 COG1741 COG1741, Pirin-related protein General function prediction only 16760778 Common - putative bacteriophage protein STY2035 16 COG4834 COG4834, Uncharacterized protein conserved in bacteria Function unknown 16762867 Common rpsD 30S ribosomal protein S4 STY4382 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 16759135 Common yacG zinc-binding protein STY0160 56 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 161501949 Common entC isochorismate synthase STY0639 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16759128 Common ftsZ cell division protein FtsZ STY0153 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 16759414 Common - probable secreted protein STY0476 10 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 16763052 Common - hypothetical protein STY4585 10 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 16762035 Common - hypothetical protein STY3451 57 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16759122 Common ftsW cell division protein FtsW STY0147 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 16760110 Common - putative mutT family protein STY1275 62 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 16759419 Common cyoE protoheme IX farnesyltransferase STY0481 172 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 16761901 Pathogen - possible membrane protein STY3291 1 None None None 16761422 Pathogen - hypothetical protein STY2745 1 None None None 16760558 Pathogen pheM phenylalanyl-tRNA synthetase operon leader peptide STY1774 1 None None None 16761164 Common yejH putative helicase STY2460 148 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 16762129 Common rnG ribonuclease G STY3550 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 16763359 Common - putative deoxyribonuclease YjjV STY4915 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 16762216 Common gppA guanosine pentaphosphate phosphohydrolase STY3641 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 16762091 Common - hypothetical protein STY3508 88 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 16760577 Common tnpA transposase for insertion sequence element IS200 STY1794 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16759660 Common - hypothetical protein STY0758 2 None None None 16761983 Common rpsU 30S ribosomal protein S21 STY3388 153 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 16763193 Common yjfC hypothetical protein STY4732 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 16760078 Common - predicted metallodependent hydrolase STY1241 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 16760595 Common - hypothetical protein STY1814 9 None None None 16760782 Common - hypothetical protein STY2039 20 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 16763049 Pathogen - possible exported protein STY4582 1 None None None 16762752 Common - puative phophotriesterase STY4261 32 COG1735 Php, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 16759361 Common yaiB hypothetical protein STY0415 6 None None None 16763124 Pathogen tviA Vi polysaccharide biosynthesis protein STY4662 1 None None None 16759320 Common stbD putative fimbrial protein STY0370 10 None None None 16761695 Common - hypothetical protein STY3048 10 None None None 16762436 Common yihD hypothetical protein STY3885 18 COG3084 COG3084, Uncharacterized protein conserved in bacteria Function unknown 16759826 Common aat leucyl/phenylalanyl-tRNA--protein transferase STY0953 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 16762721 Common - holo-(acyl carrier protein) synthase 2 STY4228 49 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 16761359 Common cysA sulfate/thiosulfate transporter subunit STY2678 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 16761763 Common - hypothetical protein STY3125 92 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 16762101 Common - transcriptional regulator NanR STY3521 130 COG2186 FadR, Transcriptional regulators Transcription 16759920 Common - putative bacteriophage protein STY1059 7 None None None 16760774 Common - putative bacteriophage protein STY2031 5 None None None 16759481 Common - hypothetical protein STY0549 69 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 16760369 Common - putative ABC transporter periplasmic binding protein STY1571 89 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 16762775 Common gntT high-affinity gluconate transporter STY4284 77 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16762500 Common torA trimethylamine-N-oxide reductase precursor STY3956 162 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16761081 Pathogen - hypothetical protein STY2367 1 None None None 161501930 Common nuoN NADH dehydrogenase subunit N STY2546 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 16761858 Common tnpA transposase for insertion sequence element IS200 STY3234 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16759985 Common hpcH 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase STY1140 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 16760496 Common ssaN type III secretion system ATPase STY1705 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 16762852 Common rpsQ 30S ribosomal protein S17 STY4367 237 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 16763034 Pathogen - hypothetical protein STY4565 4 None None None 16759132 Common mutT nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP STY0157 159 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 16759766 Common yliB putative ABC transporter periplasmic binding protein STY0888 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 16760056 Common flgH flagellar basal body L-ring protein STY1219 96 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 16759233 Common tnpA transposase for insertion sequence element IS200 STY0267 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760920 Common fliM flagellar motor switch protein FliM STY2184 109 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 16761933 Common - oxidoreductase STY3330 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16762120 Common - hypothetical protein STY3542 10 None None None 16761221 Common - hypothetical protein STY2525 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 16762746 Common ugpA glycerol-3-phosphate transporter permease STY4255 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 16759732 Common ybhN hypothetical protein STY0846 56 COG0392 COG0392, Predicted integral membrane protein Function unknown 16761848 Common - mechanosensitive channel MscS STY3223 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16759479 Common - hypothetical protein STY0547 220 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 16760935 Common yedJ hypothetical protein STY2201 61 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 16762733 Common ftsY cell division protein FtsY STY4240 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 16761609 Common srlE PTS system, glucitol/sorbitol-specific IIBC component STY2954 22 COG3732 SrlE, Phosphotransferase system sorbitol-specific component IIBC Carbohydrate transport and metabolism 16762058 Common hflB ATP-dependent metalloprotease STY3474 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 16760099 Pathogen sifA secreted effector protein STY1264 1 None None None 16760868 Common tar methyl-accepting chemotaxis protein II STY2128 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 16759443 Common glnK nitrogen regulatory protein P-II STY0506 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 16759895 Pathogen - putative bacteriophage protein STY1033 2 None None None 161501904 Common yjeQ ribosome-associated GTPase STY4709 163 COG1162 COG1162, Predicted GTPases General function prediction only 16761328 Common - aminotransferase STY2642 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 16760836 Common zwf glucose-6-phosphate 1-dehydrogenase STY2094 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 16762111 Common oadA pyruvate carboxylase subunit B STY3532 174 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 16759964 Common - putative acylphosphatase STY1110 140 COG1254 AcyP, Acylphosphatases Energy production and conversion 16763202 Common sgaA L-ascorbate-specific enzyme IIA component of PTS STY4741 45 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 16761476 Common yfhG hypothetical protein STY2810 10 None None None 16760823 Pathogen - hypothetical protein STY2078 1 None None None 16759992 Common scsB membrane protein, suppressor for copper-sensitivity B precursor STY1150 147 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16760524 Common ttrR putative two-component response regulator STY1733 202 COG4566 TtrR, Response regulator Signal transduction mechanisms 16761309 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase STY2617 223 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 16762673 Common dppB dipeptide transporter permease DppB STY4169 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16761121 Common - putative n-hydroxybenzoate transporter STY2409 103 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759675 Common kgd alpha-ketoglutarate decarboxylase STY0779 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 161501938 Common - putative voltage-gated ClC-type chloride channel ClcB STY1574 82 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 16762628 Common - putative sugar kinase STY4115 141 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 16761109 Common bglX periplasmic beta-glucosidase precursor STY2396 130 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 16759694 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase STY0801 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 16762551 Common - hypothetical protein STY4020 27 COG5464 COG5464, Uncharacterized conserved protein Function unknown 16761836 Common gcvT glycine cleavage system aminomethyltransferase T STY3211 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 16759474 Common - hypothetical protein STY0542 35 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 16762792 Common yrfF hypothetical protein STY4301 11 None None None 16759738 Common ybhF hypothetical ABC transporter ATP-binding protein STY0852 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 16762453 Common gidB glucose-inhibited division protein B STY3905 203 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 16760390 Common - hypothetical protein STY1595 12 None None None 16762553 Common mgtC conserved hyopthetical protein STY4022 120 COG1285 SapB, Uncharacterized membrane protein Function unknown 16761548 Common - putative bacteriophage late gene regulator STY2882 37 COG3500 COG3500, Phage protein D General function prediction only 16760870 Common cheA chemotaxis protein CheA STY2130 153 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 16761457 Common - cysteine desulfurase STY2789 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 16760071 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase STY1234 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16759871 Common - putative ion:amino acid symporter STY1009 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 16761518 Common yfiA translation inhibitor protein RaiA STY2853 86 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 16759835 Common dmsA anaerobic dimethyl sulfoxide reductase chain A precursor STY0962 185 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16761870 Common gshB glutathione synthetase STY3248 127 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 16763162 Common frdD fumarate reductase subunit D STY4700 24 COG3080 FrdD, Fumarate reductase subunit D Energy production and conversion 16762167 Common ysgA putative hydrolase STY3592 113 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 16761363 Common yfeF short chain dehydrogenase STY2682 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16762417 Common - predicted outer membrane porin L STY3862 5 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 16760759 Common - putative bacteriophage protein STY2016 20 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 16762595 Common waaZ lipopolysaccharide core biosynthesis protein STY4080 6 None None None 16762873 Common trkA potassium transporter peripheral membrane component STY4388 152 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 16760625 Common aroQ chorismate mutase STY1852 15 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 16760640 Common - putative cytochrome STY1868 68 COG3038 CybB, Cytochrome B561 Energy production and conversion 16759109 Pathogen leuL leu operon leader peptide STY0133 1 None None None 16761057 Common - multidrug efflux system subunit MdtC STY2341 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 16761751 Common fucO L-1,2-propanediol oxidoreductase STY3112 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 16761496 Common rseC SoxR reducing system protein RseC STY2830 19 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 16760176 Common - putative regulatory protein STY1347 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16760258 Common mdoD glucan biosynthesis protein D STY1442 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 16762085 Common - hypothetical protein STY3502 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 16761552 Common - putative phage tail protein STY2886 19 None None None 16759743 Pathogen - hypothetical protein STY0861 1 None None None 16759007 Common - putative regulatory protein STY0014 63 COG0583 LysR, Transcriptional regulator Transcription 16759955 Common yccF hypothetical protein STY1096 39 COG3304 COG3304, Predicted membrane protein Function unknown 16760437 Common - DNA-invertase STY1643 138 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 16759940 Common - hypothetical protein STY1080 17 None None None 16763021 Common pilV prepilin STY4550 12 None None None 16761882 Common tnpA transposase for insertion sequence element is200 STY3261 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16763331 Common hsdS specificity determinant for hsdM and hsdR STY4881 98 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 16761396 Common aegA putative oxidoreductase STY2717 209 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 16759217 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase STY0250 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 16763335 Common - hypothetical protein STY4887 20 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 16762098 Common - N-acetylmannosamine kinase STY3516 52 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 16763076 Common - probable phage tail fibre protein STY4611 30 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 16760623 Common - hypothetical protein STY1850 15 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 16759277 Common - hypothetical protein STY0317 3 None None None 16759570 Common - hypothetical protein STY0658 24 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 16762922 Common zur zinc uptake transcriptional repressor STY4437 131 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 16760943 Pathogen - hypothetical protein STY2209 1 None None None 16759000 Common talB transaldolase B STY0007 184 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 16759427 Common tig trigger factor STY0489 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 16760983 Common pduP putative CoA-dependent proprionaldehyde dehydrogenase STY2256 193 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16761184 Common napB diheme cytochrome c550 STY2482 41 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 16760197 Common pspB phage shock protein B STY1372 22 None None None 16760032 Common htrB lipid A biosynthesis lauroyl acyltransferase STY1192 96 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 16763288 Common - putative phage capsid protein STY4827 5 None None None 16762471 Common - probable PTS system permease STY3925 69 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 16760984 Common pduQ putative propanol dehydrogenase STY2257 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 16759243 Common - putative drug efflux protein STY0278 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16761990 Common air aerotaxis receptor protein STY3395 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 16761579 Common - hypothetical protein STY2918 65 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 16762844 Common rplD 50S ribosomal protein L4 STY4359 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 16759041 Common lspA lipoprotein signal peptidase STY0056 197 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16760486 Common cfa cyclopropane fatty acyl phospholipid synthase STY1695 143 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 16760155 Common trpB tryptophan synthase subunit beta STY1325 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 16762973 Common pmrB sensor protein BasS/PmrB STY4490 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16759709 Common ybhA predicted hydrolase STY0817 121 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16760190 Pathogen - hypothetical periplasmic protein STY1364 2 None None None 16759973 Pathogen - hypothetical protein STY1125 1 None None None 16760350 Common - hypothetical protein STY1548 12 None None None 16759189 Common mrcB penicillin-binding protein 1b STY0215 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 16760114 Common tnpA transposase for insertion sequence element IS200 STY1280 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762087 Common - hypothetical protein STY3504 8 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 16759564 Common - hypothetical protein STY0649 18 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 16759756 Common ybiS hypothetical protein STY0878 84 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 16759031 Common - hypothetical protein STY0045 5 None None None 16763182 Common hflK FtsH protease regulator HflK STY4720 212 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 161501944 Common cobB NAD-dependent deacetylase STY1261 151 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 16760406 Common - hypothetical protein STY1612 8 None None None 16762231 Pathogen ilvL ilvG operon leader peptide STY3656A 1 None None None 16763268 Common - hypothetical protein STY4806 30 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 16761370 Pathogen - hypothetical protein STY2689 1 None None None 16760359 Common - hypothetical protein STY1558 79 COG1742 COG1742, Uncharacterized conserved protein Function unknown 16761076 Pathogen - hypothetical protein STY2362 1 None None None 16762445 Common rbsD high affinity ribose transport protein RbsD STY3897 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 16760594 Common - pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase STY1813 165 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 16763090 Common - putative major capsid protein STY4625 22 None None None 16762043 Common - hypothetical protein STY3459 112 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 16759761 Common ybiY putative pyruvate formate-lyase 3 activating enzyme STY0883 61 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 16760085 Common - hypothetical protein STY1250 22 COG3150 COG3150, Predicted esterase General function prediction only 16760909 Common yedE predicted inner membrane protein STY2173 64 COG2391 COG2391, Predicted transporter component General function prediction only 16760143 Common - YciI-like protein STY1313 72 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 16760452 Common - oriC-binding nucleoid-associated protein STY1661 12 None None None 16761878 Common - putative deoxyribonucleotide triphosphate pyrophosphatase STY3256 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 16762064 Common - hypothetical protein STY3481 85 COG2962 RarD, Predicted permeases General function prediction only 16762689 Common yhjJ putative zinc-protease precursor STY4190 50 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 16761281 Common ubiX 3-octaprenyl-4-hydroxybenzoate carboxy-lyase STY2586 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 16762869 Common rplQ 50S ribosomal protein L17 STY4384 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 16761332 Common - putative ion-channel protein STY2647 194 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 16761723 Common - hypothetical protein STY3080 166 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 16760481 Common - putative secreted protein STY1690 133 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 16762194 Pathogen - hypothetical protein STY3619 1 None None None 16760709 Common - putative lipoprotein STY1949 29 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 16760299 Common narV respiratory nitrate reductase 2 gamma chain STY1485 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 16760375 Common - putative regulatory protein STY1578 178 COG0583 LysR, Transcriptional regulator Transcription 16763275 Common - putative innner membrane protein STY4813 31 COG4269 COG4269, Predicted membrane protein Function unknown 16761300 Common - hypothetical protein STY2606 8 None None None 16759238 Common yaeE DL-methionine transporter permease subunit STY0273 206 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 16760188 Pathogen - hypothetical protein STY1360 2 None None None 16761864 Common - hypothetical protein STY3242 2 None None None 16759776 Common mdfA multidrug translocase MdfA STY0899 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16763098 Common - hypothetical protein STY4635 17 None None None 16762264 Common - putative phage tail protein STY3690 28 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 16761574 Common gabT 4-aminobutyrate aminotransferase STY2912 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 16759621 Common ybeZ PhoH-like ATP-binding protein STY0715 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 16760723 Common - hypothetical protein STY1963 66 COG1971 COG1971, Predicted membrane protein Function unknown 16760948 Pathogen - hypothetical protein STY2214 5 None None None 16762326 Common talC fructose-6-phosphate aldolase STY3758 118 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 16759869 Common asnC asparaginyl-tRNA synthetase STY1004 232 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 16760021 Common csgA cryptic curlin major subunit STY1181 12 None None None 16761097 Common metG methionyl-tRNA synthetase STY2384 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16761434 Common engA GTP-binding protein EngA STY2764 229 COG1160 COG1160, Predicted GTPases General function prediction only 16761744 Common yqcC hypothetical protein STY3104 30 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 16761977 Common - putative signal transduction protein STY3382 32 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 16761995 Common - possible oxidoreductase STY3403 133 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 16763384 Common - putative transcriptional regulator protein STY4945 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16759585 Common dpiB sensor kinase DpiB STY0674 187 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 16759100 Common yabI DedA family integral membrane protein STY0122 133 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 16760739 Common - hypothetical protein STY1982 10 None None None 16763013 Pathogen pilN' PilN lipoprotein homolog (pseudogene) STY4541a 5 None None None 16760882 Common ftnA ferritin STY2143 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 16760242 Common - putative lipoprotein STY1424 27 None None None 16759377 Common tnpA transposase for insertion sequence element is200 STY0437 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16759438 Common tnpA transposase for insertion sequence element IS200 STY0500 69 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16762671 Common - hypothetical protein STY4165 20 None None None 16759715 Common hutU urocanate hydratase STY0823 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 16760223 Common - conserved hypothetical DNA-binding protein STY1400 95 COG1396 HipB, Predicted transcriptional regulators Transcription 16759264 Pathogen - hypothetical protein STY0301 1 None None None 16760288 Common - hypothetical protein STY1474 29 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 16762832 Common yheN hypothetical protein STY4347 43 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 16763294 Pathogen - hypothetical protein STY4833 1 None None None 16760234 Common - putative multidrug transporter STY1415 106 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 16760604 Common - methionine sulfoxide reductase B STY1824 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 16759950 Common - hypothetical protein STY1090 17 COG3120 COG3120, Uncharacterized protein conserved in bacteria Function unknown 16760957 Common cbiO putative cobalt transport ATP-binding protein CbiO STY2223 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 16763146 Common dcuA anaerobic C4-dicarboxylate transporter STY4684 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 16759853 Common ycaI hypothetical protein STY0984 128 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 16762697 Pathogen - phage-like lysozyme STY4198 4 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 16759938 Common pepN aminopeptidase N STY1078 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 16761473 Common - putative transmembrane transport protein STY2807 86 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 16760877 Common otsA trehalose-6-phosphate synthase STY2137 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 16763343 Common - hypothetical protein STY4898 36 COG3610 COG3610, Uncharacterized conserved protein Function unknown 16760513 Common sseB putative pathogenicity island effector effector protein STY1722 5 None None None 16759501 Common - hypothetical protein STY0574 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 16759036 Common - putative transport protein STY0050 75 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 16762640 Common - hypothetical protein STY4128 9 None None None 16760475 Common - hypothetical protein STY1684 24 COG3313 COG3313, Predicted Fe-S protein General function prediction only 16761418 Common purN phosphoribosylglycinamide formyltransferase STY2741 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 16762962 Common - heme lyase subunit NrfE STY4479 113 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16759059 Common carA carbamoyl phosphate synthase small subunit STY0076 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 16759628 Common nagB glucosamine-6-phosphate deaminase STY0722 84 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 16762588 Common waaP lipopolysaccharide core biosynthesis protein STY4073 10 None None None 16760386 Common - putative bacteriophage transcriptional regulator STY1591 13 COG5566 COG5566, Uncharacterized conserved protein Function unknown 16760732 Common htpX heat shock protein HtpX STY1975 188 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 16762435 Common yihE predicted kinase STY3884 51 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 16759009 Common - hypothetical protein STY0016 28 COG3926 zliS, Putative secretion activating protein General function prediction only 16761042 Common wcaE predicted glycosyl transferase STY2323 62 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16761413 Common - putative arsenate reductase (arsenical pump modifier) STY2736 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 16763259 Common yjgF hypothetical protein STY4798 185 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 16759632 Common - putative lipoprotein STY0726 8 None None None 16762407 Common rbn ribonuclease BN STY3851 90 COG1295 Rbn, Predicted membrane protein Function unknown 16762899 Pathogen - hypothetical protein STY4414 2 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 16761077 Pathogen - hypothetical protein STY2363 1 None None None 16761706 Common cysN sulfate adenylyltransferase subunit 1 STY3059 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 16762521 Common - hypothetical protein STY3980 4 None None None 16760466 Common ydhA putative lipoprotein STY1675 10 COG3895 COG3895, Predicted periplasmic protein General function prediction only 16759286 Common - hypothetical protein STY0327 4 None None None 16761964 Common - hypothetical protein STY3367 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 16762308 Pathogen - hypothetical protein STY3739a 2 None None None 16761774 Common ygdB hypothetical protein STY3136 7 None None None 16759517 Common fimC fimbrial chaperone protein STY0592 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 16759652 Common - PTR2-family transport protein STY0750 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 16761597 Common - putative glycoporin STY2942 12 None None None 16762826 Common kefB glutathione-regulated potassium-efflux system protein KefB STY4341 194 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 16759884 Common - conserved hypothetical bacteriophage protein STY1022 8 None None None 16762890 Common metH B12-dependent methionine synthase STY4405 177 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 16763004 Common - hypothetical protein STY4526 24 None None None 16760964 Common cbiT cobalt-precorrin-6Y C(15)-methyltransferase STY2235 113 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 16763304 Pathogen - hypothetical protein STY4852 1 None None None 16761908 Common - possible aldehyde dehydrogenase STY3298 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16763011 Common pilL hypothetical protein STY4539 26 None None None 16759560 Common - hypothetical protein STY0645 28 COG2879 COG2879, Uncharacterized small protein Function unknown 16761146 Common fruK 1-phosphofructokinase STY2441 102 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 16762477 Common - predicted hydrolase STY3931 104 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 16760397 Common - hypothetical protein STY1602 4 None None None 16763001 Common - hypothetical protein STY4523 23 COG1475 Spo0J, Predicted transcriptional regulators Transcription 16759050 Common oadG oxaloacetate decarboxylase subunit gamma STY0065 7 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 16761174 Common narP DNA-binding response regulator in two-component regulatory system with NarQ or NarX STY2472 222 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16760669 Common prfA peptide chain release factor 1 STY1901 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 16759074 Pathogen - probable secreted protein STY0093 1 None None None 16759260 Pathogen - hypothetical protein STY0295 1 None None None 16761958 Common icc cyclic 3',5'-adenosine monophosphate phosphodiesterase STY3361 81 COG1409 Icc, Predicted phosphohydrolases General function prediction only 16759490 Common sfbC ABC transporter integral membrane protein STY0560 102 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 16761465 Common - hypothetical protein STY2799 28 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 16760330 Common hyaC2 Ni/Fe-hydrogenase 1 b-type cytochrome subunit HyaC2 STY1526 51 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 16761009 Common hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein STY2287 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 16761910 Common - hypothetical protein STY3302 115 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 16760995 Common phsB thiosulfate reductase electron transport protein PhsB STY2270 167 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16760053 Common flgE flagellar hook protein FlgE STY1216 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 16762237 Pathogen - hypothetical protein STY3663 1 None None None 16760491 Common ssaS putative type III secretion protein STY1700 28 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 16762575 Common rph ribonuclease PH STY4060 189 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 16760226 Common - universal stress protein UspE STY1403 52 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 16759394 Common ribH riboflavin synthase subunit beta STY0456 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 16759202 Common yaeH hypothetical protein STY0233 17 None None None 16762388 Common - alcohol dehydrogenase STY3830 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 16762134 Common yhdA regulatory protein CsrD STY3555 144 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16763144 Common dipZ thiol:disulfide interchange protein precursor STY4682 117 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16759544 Common entD phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex STY0627 33 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 16762658 Common - hypothetical protein STY4152 8 None None None 16760613 Common - putative transcriptional regulator STY1839 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16760040 Common yceB predicted lipoprotein STY1202 19 None None None 16761236 Common menF menaquinone-specific isochorismate synthase STY2541 219 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16759288 Pathogen safA probable lipoprotein STY0332 1 None None None 16759019 Common bcfF fimbrial subunit STY0031 23 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 16760763 Common - putative bacteriophage protein STY2020 3 COG1895 COG1895, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 16761529 Common rpsP 30S ribosomal protein S16 STY2863 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 16759882 Common - putative DNA-binding protein STY1020 6 COG1396 HipB, Predicted transcriptional regulators Transcription 16762548 Common - putative PTS system protein STY4016 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 16762280 Common - transcriptional regulator HdfR STY3708 182 COG0583 LysR, Transcriptional regulator Transcription 16763235 Common fbp fructose-1,6-bisphosphatase STY4774 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 16759552 Common ybdA enterobactin exporter EntS STY0637 48 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762823 Pathogen - hypothetical protein STY4338 1 None None None 16762361 Common - putative ABC transporter ATP-binding protein STY3796 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 16761381 Common eutE putative aldehyde dehydrogenase STY2700 215 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16759699 Common galK galactokinase STY0807 92 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 16762957 Pathogen - hypothetical protein STY4474 1 None None None 16762782 Common feoA ferrous iron transport protein A STY4291 37 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 16763081 Common - putative phage tail completion protein STY4616 15 None None None 16761361 Common cysU sulfate/thiosulfate transporter subunit STY2680 233 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 16759426 Common bolA transcriptional regulator BolA STY0488 100 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 16761968 Common dsbB putative disulfide oxidoreductase STY3372 27 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 16761598 Common luxS S-ribosylhomocysteinase STY2943 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 16762972 Common proP proline/glycine betaine transporter STY4489 149 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16759021 Common - hypothetical protein STY0033 49 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 16759368 Common aroM hypothetical protein STY0423 11 None None None 16761079 Common - putative protease STY2365 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 16761034 Common wcaJ putative UDP-glucose lipid carrier transferase STY2315 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 16760696 Common nhaB sodium/proton antiporter STY1935 34 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 16759764 Common ybiK L-asparaginase STY0886 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 16761409 Common - hypothetical protein STY2730 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 16760639 Common - putative lipoprotein STY1867 4 None None None 16761628 Common hycC formate hydrogenlyase subunit 3 STY2973 202 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 16763156 Common efp elongation factor P STY4694 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 16761388 Common tnpA transposase for insertion sequence element IS200 STY2707 69 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16760211 Common - putative oxidoreductase STY1388 173 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 16760854 Common - hypothetical protein STY2112 30 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 16761711 Common - hypothetical protein STY3066 18 None None None 16761766 Common mltA murein transglycosylase A STY3128 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 16759010 Common - hypothetical protein STY0017 9 COG3710 CadC, DNA-binding winged-HTH domains Transcription 16762709 Common uspA universal stress protein A STY4212 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 16761449 Common sseB SseB protein STY2781 14 None None None 16759741 Common rhlE ATP-dependent RNA helicase RhlE STY0855 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 16760367 Common - twin-argninine leader-binding protein DmsD STY1569 26 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 16761372 Common yfeG transcriptional regulator EutR STY2691 55 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16762020 Common - possible carbohydrate kinase STY3433 152 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16760586 Common - endonuclease of nucleotide excision repair STY1804 214 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 16762255 Common nucE possible secretory protein STY3681 5 None None None 16760195 Common pspF phage shock protein operon transcriptional activator STY1370 171 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 16762221 Common ppiC peptidyl-prolyl cis-trans isomerase C STY3647 140 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 16763184 Common yjeT hypothetical protein STY4722 5 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 16761921 Common hybG hydrogenase 2 accessory protein HypG STY3314 74 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 16762762 Common asd aspartate-semialdehyde dehydrogenase STY4271 196 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 16759124 Common murC UDP-N-acetylmuramate--L-alanine ligase STY0149 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 16759110 Common leuO leucine transcriptional activator STY0134 116 COG0583 LysR, Transcriptional regulator Transcription 16759707 Common modB molybdate ABC transporter permease protein STY0815 179 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 16759849 Common - putative lipoprotein STY0979 132 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 16762397 Common fdoH formate dehydrogenase-O beta subunit STY3841 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16761115 Pathogen - hypothetical protein STY2403 1 None None None 16759906 Pathogen - putative bacteriophage protein STY1045 1 None None None 16760461 Common tppB putative tripeptide transporter permease STY1670 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 16760813 Pathogen - hypothetical protein STY2069 2 None None None 16762702 Common gor glutathione reductase STY4205 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 16759228 Common rof Rho-binding antiterminator STY0262 12 COG4568 Rof, Transcriptional antiterminator Transcription 16761519 Pathogen - phe leader peptide STY2853a 1 None None None 16759241 Common dkgB 2,5-diketo-D-gluconate reductase B STY0276 183 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 16761582 Common - hypothetical protein STY2923 13 None None None 16761288 Common cvpA colicin V production protein STY2593 100 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 16759167 Common yadF carbonic anhydrase STY0193 118 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 16759663 Common - galactosyltransferase STY0761 182 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16761063 Common - hypothetical protein STY2347 6 None None None 16761801 Common - hypothetical protein STY3168 76 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 16759791 Common - hypothetical protein STY0914 9 None None None 16760427 Common - putative bacteriophage baseplate protein STY1633 25 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 16760425 Common - putative bacteriophage tail fibre protein STY1631 6 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 16762306 Common secE preprotein translocase subunit SecE STY3738 68 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 16759680 Common cydB cytochrome d ubiquinol oxidase subunit II STY0787 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 16759795 Common - putative phosphotransferase enzyme II, B component STY0918 7 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 16761368 Common amiA N-acetylmuramoyl-l-alanine amidase I STY2687 181 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 16760816 Common racC hypothetical protein STY2072 3 None None None 16763360 Common - hypothetical protein STY4916 67 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 16759097 Common araA L-arabinose isomerase STY0119 36 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 16759307 Common yafK hypothetical protein STY0357 49 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 16760442 Common - outer membrane protein STY1649 29 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 16762357 Common yneB aldolase STY3792 74 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 161501900 Common - hypothetical protein STY4855 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 16763228 Common msrA methionine sulfoxide reductase A STY4767 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 16761104 Common - hypothetical protein STY2391 4 None None None 16760139 Common oppF oligopeptide transport ATP-binding protein OppF STY1309 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 16759258 Pathogen - hypothetical protein STY0293 1 None None None 16760660 Common - hypothetical protein STY1889 30 COG3926 zliS, Putative secretion activating protein General function prediction only 16762888 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein STY4403 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 16759984 Common hpcG 2-oxo-hepta-3-ene-1,7-dioic acid hydratase STY1139 63 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 16762240 Common - hypothetical protein STY3666 5 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 16759465 Common recR recombination protein RecR STY0530 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 16761733 Pathogen - hypothetical protein STY3092 1 None None None 16761316 Common vacJ VacJ lipoprotein precursor STY2624 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 16759085 Common ksgA dimethyladenosine transferase STY0105 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 16761621 Pathogen - hypothetical protein STY2966 3 None None None 16759442 Common mdlB putative multidrug transporter membrane\ATP-binding components STY0504 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 16763286 Common - phage polarity suppression protein STY4825 6 None None None 16761903 Common - LysR-family transcriptional regulator STY3293 110 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16761669 Pathogen spaN surface presentation of antigens protein (associated with type III secretion and virulence) STY3015 2 None None None 16761761 Common - possible lipoprotein STY3123 13 None None None 16761433 Common - hypothetical protein STY2763a 10 None None None 16759736 Common - putative inner membrane protein STY0850 184 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 16761016 Common rfbN putative rhamnosyltransferase STY2294 66 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 16762103 Common sspA stringent starvation protein A STY3523 108 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16762711 Common pitA putative low-affinity inorganic phosphate transporter STY4214 155 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 16762992 Pathogen - hypothetical protein STY4513 1 None None None 16763111 Common - Putative methyltransferase STY4649 129 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 16760687 Common - hypothetical protein STY1925 62 COG2261 COG2261, Predicted membrane protein Function unknown 16760766 Common - putative bacteriophage protein STY2023 8 None None None 16759460 Common ybaM hypothetical protein STY0524 13 None None None 16760439 Common - hypothetical protein STY1646 14 COG3136 GlpM, Uncharacterized membrane protein required for alginate biosynthesis General function prediction only 16761193 Common ada ADA regulatory protein STY2491 206 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 16762005 Common - hypothetical protein STY3413 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16760138 Common oppD oligopeptide transporter ATP-binding component STY1308 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 16760541 Common - hypothetical protein STY1757 84 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 16761794 Common araE L-arabinose isomerase STY3160 176 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16763309 Common - hypothetical protein STY4857 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 16760937 Common ompS1 outer membrane protein S1 STY2203 20 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 16762691 Common yhjH EAL domain containing protein involved in flagellar function STY4192 125 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16759452 Common maA maltose O-acetyltransferase STY0515 96 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 16762208 Common rffG dTDP-glucose 4,6-dehydratase STY3633 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 16763164 Common frdB fumarate reductase iron-sulfur subunit STY4702 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 16761587 Common nrdH glutaredoxin-like protein STY2930 36 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 16760714 Common pabB para-aminobenzoate synthase component I STY1954 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 16759353 Common ampH beta-lactamase/D-alanine carboxypeptidase STY0407 116 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 16760704 Common minC septum formation inhibitor STY1944 92 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 16760975 Common pduE diol dehydratase small subunit STY2247 13 COG4910 PduE, Propanediol dehydratase, small subunit Secondary metabolites biosynthesis, transport, and catabolism 16760673 Common prsA ribose-phosphate pyrophosphokinase STY1906 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 16760522 Common - putative pathogenicity island protein STY1731 65 COG3272 COG3272, Uncharacterized conserved protein Function unknown 16760509 Common sseE putative pathogenicity island effector protein STY1718 3 None None None 16762033 Common - DnaA initiator-associating protein DiaA STY3449 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 16760322 Common - putative regulatory protein STY1514 25 COG1846 MarR, Transcriptional regulators Transcription 16761633 Common hypC hydrogenase isoenzymes formation protein STY2978 75 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 16761974 Common rfaE bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase STY3379 188 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 16763118 Common tviE Vi polysaccharide biosynthesis protein TviE, Glycosyl transferase group 1 STY4656 168 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16761685 Common - possible membrane transport protein STY3036 169 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16762156 Common yigC 3-octaprenyl-4-hydroxybenzoate decarboxylase STY3581 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 16760173 Common pyrF orotidine 5'-phosphate decarboxylase STY1344 162 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 16760216 Common - putative transcriptional regulator STY1393 141 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 16759604 Common nadD nicotinic acid mononucleotide adenyltransferase STY0696 170 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 16760895 Common yecF hypothetical protein STY2157 10 None None None 16761640 Common sitC Iron transport protein, inner membrane component STY2985 191 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 16761615 Common gutQ D-arabinose 5-phosphate isomerase STY2960 155 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 16762487 Common dnaA chromosomal replication initiation protein STY3940 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 16759683 Common ybgC acyl-CoA thioester hydrolase YbgC STY0790 131 COG0824 FcbC, Predicted thioesterase General function prediction only 16762929 Common tyrB aromatic amino acid aminotransferase STY4444 76 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 16761846 Common - hypothetical protein STY3221 59 COG2968 COG2968, Uncharacterized conserved protein Function unknown 16760884 Common tyrP tyrosine-specific transport protein STY2145 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16759830 Common lrp leucine-responsive transcriptional regulator STY0957 158 COG1522 Lrp, Transcriptional regulators Transcription 16763088 Common - putative capsid completion protein STY4623 17 None None None 16760045 Common mviM putative virulence factor MviM STY1207 142 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 16760221 Common - hypothetical protein STY1398 9 None None None 16762910 Common malE maltose ABC transporter periplasmic protein STY4425 95 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 16763217 Common - hypothetical protein STY4756 3 None None None 16761311 Common - phosphohistidine phosphatase STY2619 56 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 16759945 Common pqiB paraquat-inducible protein B STY1085 69 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 161501929 Common - putative phosphatase STY2564 141 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 16759171 Common yadE hypothetical protein STY0197 85 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 16762027 Common gatC PTS system, galactitol-specific IIC component STY3443 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 16763121 Common tviD Vi polysaccharide biosynthesis protein STY4659 3 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16762871 Common zntR zinc-responsive transcriptional regulator STY4386 157 COG0789 SoxR, Predicted transcriptional regulators Transcription 16762450 Common asnC DNA-binding transcriptional regulator AsnC STY3902 155 COG1522 Lrp, Transcriptional regulators Transcription 16759404 Common phnU probable membrane component of 2-aminoethylphosphonate transporter STY0466 218 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 161501951 Common rdgC recombination associated protein STY0425 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 16761152 Common yeiR hypothetical protein STY2448 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 16762037 Common - hypothetical protein STY3453 20 COG3787 COG3787, Uncharacterized protein conserved in bacteria Function unknown 16762165 Common yigN DNA recombination protein RmuC STY3590 142 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 16761487 Common - putative transcriptional regulator STY2821 192 COG0583 LysR, Transcriptional regulator Transcription 161501925 Common corB hypothetical protein STY2866 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 16761899 Pathogen - hypothetical protein STY3289 2 None None None 16761331 Common - putative decarboxylase STY2646 220 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 16762276 Common - putative regulator of late gene expression STY3702 37 COG3500 COG3500, Phage protein D General function prediction only 16762716 Common - putative aminotransferase STY4221 219 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 16760942 Common - hypothetical protein STY2208 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 16762011 Common tdcG L-serine dehydratase STY3422 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 16762859 Common rplR 50S ribosomal protein L18 STY4374 209 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 16761056 Common yegN multidrug efflux system subunit MdtB STY2340 181 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 16760339 Common - putative aldehyde-dehydrogenase STY1536 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 16760746 Common - hypothetical protein STY1993 2 None None None 16759788 Common potG putrescine transporter ATP-binding subunit STY0911 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 16762799 Common hofQ predicted fimbrial transporter STY4308 141 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 16762937 Pathogen - hypothetical protein STY4452 1 None None None 16759417 Pathogen - probable secreted protein STY0479 2 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 16759546 Common fes enterobactin/ferric enterobactin esterase STY0629 27 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 16761716 Common - hypothetical protein STY3071 81 COG1203 COG1203, Predicted helicases General function prediction only 16759150 Common aceF dihydrolipoamide acetyltransferase STY0176 198 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 16762904 Common - putative lipoprotein STY4419 13 None None None 16762006 Common - hypothetical protein STY3414 45 COG3152 COG3152, Predicted membrane protein Function unknown 16762915 Common ubiA 4-hydroxybenzoate octaprenyltransferase STY4430 158 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 16759591 Common tatE twin arginine translocase protein E STY0682 32 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 16760069 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III STY1232 230 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 16762944 Common - hypothetical protein STY4461 7 None None None 16759488 Common sfbA lipoprotein STY0558 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 161501906 Common - phosphoglyceromutase STY4091 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 16763378 Common creB DNA-binding response regulator CreB STY4935 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16759119 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase STY0144 204 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 16759811 Common - hypothetical protein STY0934 49 COG2431 COG2431, Predicted membrane protein Function unknown 16761946 Pathogen - hypothetical protein STY3345 1 None None None 16760430 Common - putative bacteriophage tail fiber protein STY1636 11 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 16761020 Common rfbE CDP-tyvelose-2-epimerase STY2298 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 16761503 Common yfiK neutral amino-acid efflux protein STY2838 97 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 16763067 Common - putative regulator of late gene expression STY4601 38 COG3500 COG3500, Phage protein D General function prediction only 16759144 Common ampE regulatory protein AmpE STY0169 17 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 16760556 Common pheT phenylalanyl-tRNA synthetase subunit beta STY1772 246 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 16760793 Common - hypothetical protein STY2050 4 None None None 16760958 Common cbiQ putative cobalt transport protein CbiQ STY2224 48 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 16760329 Common hyaA2 uptake hydrogenase small subunit STY1523 79 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 16762510 Common ccmH2 cytochrome c-type biogenesis protein H2 STY3966 87 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 16759840 Common ycaM probable transport protein STY0967 72 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16759067 Common caiT L-carnitine/gamma-butyrobetaine antiporter STY0084 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 16760535 Common - cysteine desulfurase activator complex subunit SufD STY1751 176 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 16761004 Common hisC histidinol-phosphate aminotransferase STY2282 235 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 16760733 Common prc carboxy-terminal protease STY1976 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 16761258 Common - putative sodium/sulphate transporter STY2563 130 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 16760652 Pathogen - hypothetical protein STY1879 1 None None None 16763044 Common - hypothetical protein STY4576 22 None None None 16761533 Common - hypothetical protein STY2867 3 None None None 16760805 Pathogen - hypothetical protein STY2061 4 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 16761650 Common prgI pathogenicity 1 island effector protein STY2994 8 None None None 16759816 Common cspD cold shock-like protein CspD STY0940 179 COG1278 CspC, Cold shock proteins Transcription 16761357 Common - hypothetical protein STY2676 6 None None None 16760108 Common - hypothetical protein STY1273 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 16759837 Common dmsC anaerobic dimethyl sulfoxide reductase chain C STY0964 23 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 16759157 Common kdgT 2-keto-3-deoxygluconate permease STY0183 27 None None None 16759932 Common - putative bacteriophage protein STY1071 10 None None None 16761251 Common nuoC bifunctional NADH:ubiquinone oxidoreductase subunit C/D STY2556 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 16759340 Pathogen - hypothetical protein STY0394 1 None None None 16760094 Common - outer membrane-specific lipoprotein transporter subunit LolE STY1259 155 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 16762119 Common argR arginine repressor STY3540 75 COG1438 ArgR, Arginine repressor Transcription 16759329 Common - possible outer membrane protein STY0380 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16762144 Common fis DNA-binding protein Fis STY3565 97 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 16761810 Common - hypothetical protein (assiciated with virulence) STY3182 62 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 16762790 Common hslR ribosome-associated heat shock protein Hsp15 STY4299 113 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 16760315 Common - putative hydrolase STY1503 168 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 16761277 Common hisM histidine transport system permease STY2582 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 16759523 Pathogen - hypothetical protein STY0599 2 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 16761294 Common usg hypothetical protein STY2600 167 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 16762295 Common thiF thiamine biosynthesis protein ThiF STY3723 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 16762456 Common atpE F0F1 ATP synthase subunit C STY3908 50 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 16760186 Common - integrase (fragment) STY1358 68 None None None 16761270 Common - putative transcriptional regulator STY2575 126 COG1609 PurR, Transcriptional regulators Transcription 16759925 Common - putative bacteriophage protein STY1064 9 None None None 16762950 Common - putative sodium/hydrogen exchanger family protein STY4467 108 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 16759182 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase STY0208 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 16760563 Pathogen rfc O-antigen polymerase STY1779 2 None None None 16759134 Common - putative lysR-family transcriptional regulator STY0159 187 COG0583 LysR, Transcriptional regulator Transcription 16761954 Common - sensor protein QseC STY3355 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16759645 Common kdpE DNA-binding response regulator in two-component regulatory system with KdpD STY0743 205 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16760859 Common argS arginyl-tRNA synthetase STY2117 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161501918 Common garR tartronate semialdehyde reductase STY3430 179 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 16759300 Pathogen - hypothetical protein STY0350 1 None None None 16760951 Pathogen - hypothetical protein STY2217 1 None None None 16762341 Common cytR DNA-binding transcriptional regulator CytR STY3776 126 COG1609 PurR, Transcriptional regulators Transcription 16761246 Common nuoI NADH dehydrogenase subunit I STY2551 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 16761783 Common - hypothetical protein STY3149 94 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 16762427 Common glnG nitrogen regulation protein NR(I) STY3876 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 161501913 Common murI glutamate racemase STY3743 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 16759151 Common lpdA dihydrolipoamide dehydrogenase STY0177 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 16760239 Common hslJ heat-inducible protein STY1421 14 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 16762695 Common yhjC hypothetical lysR-family transcriptional regulator STY4196 182 COG0583 LysR, Transcriptional regulator Transcription 16761649 Common prgJ pathogenicity 1 island effector protein STY2993 5 None None None 16761949 Common plsC 1-acyl-glycerol-3-phosphate acyltransferase STY3350 92 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 16759916 Common - putative bacteriophage protein STY1055 6 None None None 16761935 Common exbB biopolymer transport protein ExbB STY3332 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 16763036 Common - possible exported protein STY4568 19 None None None 16762428 Common hemN coproporphyrinogen III oxidase STY3877 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 16761655 Common stpA tyrosine phosphatase (associated with virulence) STY3001 5 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 16761240 Common - putative receptor/regulator protein STY2545 118 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 16760249 Common - hypothetical protein STY1433 11 None None None 161501917 Common - ATP-dependent RNA helicase DeaD STY3461 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 16759316 Common proB gamma-glutamyl kinase STY0366 193 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 16760262 Common - putative regulatory protein STY1446 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16762801 Common aroB 3-dehydroquinate synthase STY4310 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 16759657 Pathogen - hypothetical protein STY0755 1 None None None 16761166 Common - hypothetical protein STY2462 2 None None None 16759965 Common - sulfurtransferase TusE STY1111 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 16760691 Common - potassium/proton antiporter STY1929 139 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 16762808 Common cysG siroheme synthase STY4319 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 16761798 Common - possible regulatory protein STY3165 182 COG0583 LysR, Transcriptional regulator Transcription