Neisseria meningitidis Z2491, complete genome NC_003116 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 15794300 Common lipB lipoate-protein ligase B NMA1379 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 15794543 Common - hypothetical protein NMA1649 73 COG1556 COG1556, Uncharacterized conserved protein Function unknown 15794150 Common - oxidoreductase NMA1206 176 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 15793338 Common pyrH uridylate kinase NMA0326 240 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 15793076 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II NMA0044 211 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15794414 Common - nucleotide-binding protein NMA1520 98 COG1485 COG1485, Predicted ATPase General function prediction only 15793969 Common - hypothetical protein NMA1013 81 COG1469 COG1469, Uncharacterized conserved protein Function unknown 15793150 Common rplP 50S ribosomal protein L16 NMA0122 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 15794118 Pathogen - cell-surface protein NMA1173 1 None None None 15793345 Common - adhesin component NMA0335 3 None None None 15795080 Common - hypothetical protein NMA2211 57 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 15794404 Common fpg formamidopyrimidine-DNA glycosylase NMA1505 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 15793262 Common pncA nicotinamidase NMA0244 61 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 15793530 Common - ABC transporter ATP-binding protein NMA0535 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15794030 Pathogen - hypothetical protein NMA1082 1 None None None 15794446 Common proS prolyl-tRNA synthetase NMA1553 241 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793145 Common rplE 50S ribosomal protein L5 NMA0117 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 15793548 Common - IS1016 transposase NMA0554 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794463 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B NMA1570 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 15794913 Common acpS holo-(acyl-carrier protein) synthase NMA2033 72 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 15794909 Common - hypothetical protein NMA2029 32 COG3177 COG3177, Uncharacterized conserved protein Function unknown 15793471 Common - sodium-dependent inner membrane transport protein NMA0470 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 15793846 Pathogen - hypothetical protein NMA0877 1 None None None 15794927 Common - hypothetical protein NMA2049 226 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 15794093 Common - hypothetical protein NMA1147 34 COG2938 COG2938, Uncharacterized conserved protein Function unknown 15794956 Common - chelatase NMA2080 191 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 15793919 Common - D-alanyl-D-alanine-endopeptidase NMA0962 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15793402 Common - hypothetical protein NMA0394 19 None None None 15793372 Common - oxidoreductase NMA0364 55 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15794677 Pathogen - hypothetical protein NMA1784 2 None None None 15794497 Pathogen - hypothetical protein NMA1602 1 None None None 15793162 Common tufA1 elongation factor Tu NMA0134 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15794490 Common - HesB-like protein NMA1597 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 15793313 Pathogen - periplasmic protein NMA0299 1 None None None 15794091 Common sdhA succinate dehydrogenase flavoprotein subunit NMA1145 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 15793389 Common metR transcriptional activator protein METR NMA0381 189 COG0583 LysR, Transcriptional regulator Transcription 15793105 Common - parA family protein NMA0076 207 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15793156 Common rplD 50S ribosomal protein L4 NMA0128 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 15793797 Common ppsA phosphoenolpyruvate synthase NMA0826 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15793270 Common - oxidoreductase NMA0252 100 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 15793823 Pathogen mafB3 adhesin NMA0853 2 None None None 15794054 Common - membrane protein NMA1107 6 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 15794363 Common - dnaJ-family protein NMA1461 233 COG3671 COG3671, Predicted membrane protein Function unknown 15793679 Pathogen - periplasmic protein NMA0698 1 None None None 15794798 Pathogen - hypothetical protein NMA1913 1 None None None 15793897 Pathogen - hypothetical protein NMA0939 1 None None None 15793654 Pathogen - hypothetical protein NMA0671 1 None None None 15793485 Common - ABC transport inner membrane subunit NMA0486 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 15793088 Common sdaA L-serine dehydratase NMA0057 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 15793907 Common rbgA ribosomal biogenesis GTPase NMA0950 104 COG1161 COG1161, Predicted GTPases General function prediction only 15794373 Common - protein-tyrosine-phosphatase NMA1472 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 15793962 Common - hypothetical protein NMA1006 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 15794538 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase NMA1644 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 15793870 Common trpB tryptophan synthase subunit beta NMA0904 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 15795006 Common - hypothetical protein NMA2135 165 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 15794920 Common - integral membrane efflux protein NMA2040 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15793889 Common infC translation initiation factor IF-3 NMA0930 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 15793769 Common rpsP 30S ribosomal protein S16 NMA0795 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 15794425 Common pss phosphatidylserine synthase NMA1532 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 15793250 Common - hypothetical protein NMA0228 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 15794041 Common prsA ribose-phosphate pyrophosphokinase NMA1093 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15793429 Pathogen - pilin NMA0424 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 15793139 Common rpmD 50S ribosomal protein L30 NMA0111 50 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 15794387 Common - IS1016 transposase NMA1487 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793760 Pathogen - hypothetical protein NMA0785 1 None None None 15794098 Pathogen - membrane protein NMA1152 1 None None None 15794530 Pathogen - hypothetical protein NMA1636 1 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15794772 Common - regulator NMA1884 48 COG2932 COG2932, Predicted transcriptional regulator Transcription 15793157 Common rplC 50S ribosomal protein L3 NMA0129 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 15794380 Common - periplasmic protein NMA1480 17 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 15793834 Common ligA DNA ligase NMA0865 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15794528 Common - ATP-dependent RNA helicase NMA1634 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15793412 Common - D,D-heptose 1,7-bisphosphate phosphatase NMA0405 129 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 15794146 Common - acyl-CoA dehydrogenase NMA1202 130 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 15793255 Common - hypothetical protein NMA0237 175 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 15793598 Common carA carbamoyl phosphate synthase small subunit NMA0608 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 15794646 Common - hypothetical protein NMA1753 88 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15794201 Common proB gamma-glutamyl kinase NMA1268 193 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 15795051 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase NMA2180 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 15793565 Pathogen - hypothetical protein NMA0574 1 None None None 15794544 Common - iron-sulphur protein NMA1650 97 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 15793518 Common atpC F0F1 ATP synthase subunit epsilon NMA0520 164 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 15794397 Common - iron-sulphur binding protein NMA1497 33 COG0633 Fdx, Ferredoxin Energy production and conversion 15793923 Common - thioredoxin NMA0966 19 None None None 15794779 Common serC phosphoserine aminotransferase NMA1894 111 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 15793695 Common hemC porphobilinogen deaminase NMA0718 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 15794879 Common - hypothetical protein NMA1999 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 15794599 Common pncB nicotinate phosphoribosyltransferase NMA1706 94 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 15793705 Common - ABC transporter ATP-binding protein NMA0729 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15793685 Common - hypothetical protein NMA0707 168 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 15794126 Common - integral membrane protein NMA1181 8 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 15793990 Common rfaE DP-heptose synthetase NMA1034 138 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 15794983 Common - phosphate permease NMA2109 171 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 15793893 Common - hypothetical protein NMA0935 22 COG1106 COG1106, Predicted ATPases General function prediction only 15794458 Common - aldehyde dehydrogenase NMA1565 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15794032 Common - periplasmic protein NMA1084 3 None None None 15795073 Common - hypothetical protein NMA2204 152 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 15793528 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase NMA0533 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15794073 Common - RNA methylase NMA1127 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15794759 Common - hypothetical protein NMA1871 18 None None None 15794866 Common exbB biopolymer transport protein NMA1984 151 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15793433 Common - hypothetical protein NMA0428 24 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 15794226 Pathogen - hypothetical protein NMA1297 1 None None None 15793065 Common - hypothetical protein NMA0032 145 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 15794694 Common - two component sensor kinase NMA1803 80 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 15793749 Common - hypothetical protein NMA0774 9 None None None 15793419 Common - permease NMA0414 190 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 15793522 Common lgtA lacto-N-neotetraose biosynthesis glycosyl tranferase NMA0524 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15794012 Common engA GTP-binding protein EngA NMA1063 225 COG1160 COG1160, Predicted GTPases General function prediction only 15793640 Common ponA penicillin-binding protein 1 NMA0655 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 15794177 Common - hypothetical protein NMA1237 61 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 15794160 Pathogen - hypothetical protein NMA1218 1 None None None 15794355 Common leuC isopropylmalate isomerase large subunit NMA1450 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 15793666 Pathogen - hypothetical protein NMA0685 1 None None None 15795028 Common - hypothetical protein NMA2157 201 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 15793643 Common - membrane protein NMA0659 62 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 15794639 Common dgk diacylglycerol kinase NMA1746 66 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 15793775 Common - hypothetical protein NMA0801 12 COG3308 COG3308, Predicted membrane protein Function unknown 15793948 Common hemE uroporphyrinogen decarboxylase NMA0991 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 161353793 Common ribC riboflavin synthase subunit alpha NMA1416 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 15793722 Common nqrF Na(+)-translocating NADH-quinone reductase subunit F NMA0747 167 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 15793086 Common - integral membrane protein NMA0055 13 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15794747 Common - hypothetical protein NMA1859 18 COG3422 COG3422, Uncharacterized conserved protein Function unknown 15794443 Common - hypothetical protein NMA1550 131 COG1678 COG1678, Putative transcriptional regulator Transcription 15793233 Common dnaJ DnaJ protein NMA0209 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15793490 Common - hypothetical protein NMA0491 6 None None None 15793352 Common - hypothetical protein NMA0342 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 15793475 Common hpuB haemoglobin-haptoglobin-utilization protein NMA0474 47 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15794892 Common - hypothetical protein NMA2012 14 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 15794829 Common - hypothetical protein NMA1946 235 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15794954 Common - thiol:disulphide interchange protein NMA2078 66 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15794717 Common - hypothetical protein NMA1827 8 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 15794696 Common - hypothetical protein NMA1806 50 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 15794586 Common surE SurE protein NMA1693 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 15793350 Common gmhA phosphoheptose isomerase NMA0340 123 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 15793604 Common - NADH:FMN oxidoreductase NMA0614 98 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 15794141 Pathogen - hypothetical protein NMA1197 1 None None None 15794247 Common - hypothetical protein NMA1320 16 COG4379 COG4379, Mu-like prophage tail protein gpP General function prediction only 15794433 Common uvrC excinuclease ABC subunit C NMA1540 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15793095 Common dapB dihydrodipicolinate reductase NMA0066 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 15793209 Pathogen - hypothetical protein NMA0181 1 None None None 15794330 Common - two-component system sensor kinase NMA1418 138 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 15795064 Common - hypothetical protein NMA2195 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 15794167 Common - phage repressor NMA1225 8 COG1476 COG1476, Predicted transcriptional regulators Transcription 15794995 Pathogen - hypothetical protein NMA2123 1 None None None 15793712 Common dnaK molecular chaperone DnaK NMA0736 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 161353795 Common ppc phosphoenolpyruvate carboxylase NMA0374 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 15794686 Pathogen - hypothetical protein NMA1795 1 None None None 15794628 Common secA preprotein translocase subunit SecA NMA1735 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 15793202 Pathogen - integral membrane protein NMA0174 1 None None None 15794489 Common - scaffold protein NMA1596 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 15794194 Common - integral membrane protein NMA1261 153 COG0344 COG0344, Predicted membrane protein Function unknown 15794859 Common - cytochrome c NMA1977 81 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 15794702 Common fumA fumarate hydratase NMA1812 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15793176 Common secE preprotein translocase subunit SecE NMA0148 23 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 15794818 Pathogen - hypothetical protein NMA1935 1 None None None 15794774 Common nor nitric oxide reductase NMA1886 72 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 15793137 Common secY preprotein translocase subunit SecY NMA0109 249 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 15793724 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D NMA0749 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 15794832 Common - phosphoglucomutase/phosphomannomutase NMA1949 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15794740 Common - hypothetical protein NMA1852 12 None None None 15793499 Pathogen - hypothetical protein NMA0500 1 None None None 15793581 Common - hypothetical protein NMA0590 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15793950 Common - periplasmic protein NMA0993 36 COG3439 COG3439, Uncharacterized conserved protein Function unknown 15793367 Pathogen - periplasmic protein NMA0358 1 None None None 15794843 Pathogen - hypothetical protein NMA1960 1 None None None 15794973 Common mapA maltose phosphorylase NMA2098 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 15793876 Common - hypothetical protein NMA0911 164 COG1496 COG1496, Uncharacterized conserved protein Function unknown 15794317 Pathogen - periplasmic protein NMA1405 1 None None None 15794484 Common - type III restriction/modification system enzyme NMA1591 9 COG3421 COG3421, Uncharacterized protein conserved in bacteria Function unknown 15794269 Common - hypothetical protein NMA1347 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 15794656 Common ilvC ketol-acid reductoisomerase NMA1763 211 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 15794961 Common xthA exodeoxyribonuclease III NMA2086 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15794763 Pathogen - hypothetical protein NMA1875 1 None None None 15793999 Common - hypothetical protein NMA1048 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15793715 Common - hypothetical protein NMA0739 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 15793359 Common - nuclease NMA0348 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15794228 Pathogen - hypothetical protein NMA1299 1 None None None 15794521 Common pepN aminopeptidase N NMA1627 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 15794025 Pathogen - hypothetical protein NMA1077 1 None None None 15794286 Common cysD sulfate adenylyltransferase subunit 2 NMA1365 126 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15793214 Common lipA capsule polysaccharide modification protein NMA0186 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 15794479 Common rbfA ribosome-binding factor A NMA1586 168 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 15794309 Pathogen - membrane protein NMA1396 1 None None None 15793789 Common - polyamine permease ATP-binding protein NMA0816 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15794005 Common - hypothetical protein NMA1056 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 15793623 Common - hypothetical protein NMA0635 121 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 15794933 Common prpB 2-methylisocitrate lyase NMA2055 135 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 15793638 Common pilN pilus assembly protein NMA0653 39 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 15793935 Common pfs 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NMA0978 92 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15795012 Common - hypothetical protein NMA2141 31 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15793045 Common - hypothetical protein NMA0011 32 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 15794385 Common gcr site-specific recombinase NMA1485 23 COG4389 COG4389, Site-specific recombinase DNA replication, recombination, and repair 15794262 Common - oxidoreductase NMA1338 37 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 15793254 Pathogen - hypothetical protein NMA0236 1 None None None 15793458 Pathogen - hypothetical protein NMA0455 1 None None None 15794086 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase NMA1140 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 15793224 Common sacA UDP-N-acetyl-D-glucosamine 2-epimerase NMA0199 157 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 15794233 Pathogen - hypothetical protein NMA1304 1 None None None 15794299 Common lipA lipoyl synthase NMA1378 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 15794734 Pathogen - hypothetical protein NMA1845 1 None None None 15794947 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase NMA2071 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15794108 Pathogen - hypothetical protein NMA1162 1 None None None 15793986 Pathogen - hypothetical protein NMA1030 1 None None None 15793555 Pathogen - hypothetical protein NMA0563 1 None None None 15793117 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase NMA0088 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 15794576 Common clpB ClpB protein NMA1683 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15794619 Common smpB SsrA-binding protein NMA1726 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 15795087 Common - tRNA/rRNA methyltransferase NMA2218 166 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 15793328 Pathogen - hypothetical protein NMA0316 2 None None None 15794046 Common cysW sulphate permease inner membrane protein NMA1098 209 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 15793819 Common - putative deoxyribonucleotide triphosphate pyrophosphatase NMA0849 233 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 15793754 Pathogen - integral membrane protein NMA0779 1 None None None 15794626 Common - H.8 outer membrane protein NMA1733 19 COG3241 COG3241, Azurin Energy production and conversion 15793967 Common hemB delta-aminolevulinic acid dehydratase NMA1011 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 15793955 Common - amino acid permease integral membrane protein NMA0999 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15793540 Common maf Maf-like protein NMA0546 179 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 15793858 Common era GTP-binding protein Era NMA0889 216 COG1159 Era, GTPase General function prediction only 15794185 Common dedA DedA protein ortholog NMA1250 164 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15794562 Common - ferredoxin NMA1668 76 COG0348 NapH, Polyferredoxin Energy production and conversion 15793578 Common fba fructose-1,6-bisphosphate aldolase NMA0587 175 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15795039 Common emrB multidrug resistance translocase NMA2168 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15794270 Common - hypothetical protein NMA1348 83 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 15794302 Common - integral membrane protein NMA1381 128 COG0628 PerM, Predicted permease General function prediction only 15793172 Common rplJ 50S ribosomal protein L10 NMA0144 210 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 15794672 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NMA1779 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15793912 Common - hypothetical protein NMA0955 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 15794475 Pathogen - hypothetical protein NMA1582 1 None None None 15793143 Common rpsH 30S ribosomal protein S8 NMA0115 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 15795090 Common ruvA Holliday junction DNA helicase motor protein NMA2221 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 15794279 Common bioB biotin synthase NMA1358 178 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15794409 Common rpsA 30S ribosomal protein S1 NMA1515 221 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 15793392 Common petB cytochrome B NMA0384 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 15793399 Common ptsH sugar transport PTS system phosphocarrier protein HPR NMA0391 146 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 15795097 Common nuoN NADH dehydrogenase subunit N NMA2228 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 15795041 Common - 7-cyano-7-deazaguanine reductase NMA2170 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 15794750 Pathogen - hypothetical protein NMA1862 2 None None None 15793436 Common - inner membrane protein NMA0431 6 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15794337 Pathogen - hypothetical protein NMA1426 1 None None None 15794667 Common - transcriptional regulator NMA1774 13 COG1846 MarR, Transcriptional regulators Transcription 15794505 Common eda keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase NMA1611 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 15793160 Pathogen - hypothetical protein NMA0132A 1 None None None 15793645 Common gcp O-sialoglycoprotein endopeptidase NMA0661 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 15794742 Common - hypothetical DNA-binding protein NMA1854 7 None None None 15794558 Common - ferredoxin NADP+ reductase NMA1664 107 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 15794845 Common - hypothetical protein NMA1962 53 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 15793973 Common ppnK inorganic polyphosphate/ATP-NAD kinase NMA1017 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 15793795 Pathogen - hypothetical protein NMA0824 1 None None None 15794499 Common pgi glucose-6-phosphate isomerase NMA1604 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 15794365 Common - hypothetical protein NMA1463 128 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15793585 Common prmA ribosomal protein L11 methyltransferase NMA0595 181 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 15794904 Common tbpA transferrin-binding protein A NMA2024 68 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15794551 Common - hypothetical protein NMA1657 187 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 15794416 Common - hypothetical protein NMA1522 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 15793067 Common glnE glutamate-ammonia-ligase adenylyltransferase NMA0035 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 15794292 Common vacB ribonuclease NMA1371 196 COG0557 VacB, Exoribonuclease R Transcription 15794375 Pathogen - hypothetical protein NMA1474 2 None None None 15793652 Common - transmembrane transport protein NMA0668 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 15794316 Pathogen - hypothetical protein NMA1404 1 None None None 15793780 Common - nucleotide-binding protein NMA0806 226 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15793169 Common rpoC DNA-directed RNA polymerase subunit beta' NMA0141 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15794407 Common - ribosomal small subunit pseudouridine synthase NMA1508 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15793323 Pathogen - hypothetical protein NMA0311 1 None None None 15793154 Common rplB 50S ribosomal protein L2 NMA0126 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 15794566 Common ssb single-stranded binding protein NMA1672 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15794541 Common - integral membrane protein NMA1647 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15794369 Pathogen - hypothetical protein NMA1468 1 None None None 15793630 Common ribD diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase NMA0644 232 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 15793785 Common secD preprotein translocase subunit SecD NMA0812 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 15793909 Common recN DNA repair protein NMA0952 205 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 15794113 Common - hypothetical protein NMA1168 5 None None None 15793960 Common pth peptidyl-tRNA hydrolase NMA1004 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 15794536 Common porA porin, class I outer membrane protein NMA1642 29 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15793677 Pathogen - hypothetical protein NMA0696A 3 None None None 15794389 Pathogen - hypothetical protein NMA1489 1 None None None 15794514 Common - cytolysin secretion ABC transporter NMA1620 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 15793778 Common - sec-independent protein translocase component NMA0804 81 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 15794428 Common rpsR 30S ribosomal protein S18 NMA1535 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 15794333 Common purM phosphoribosylaminoimidazole synthetase NMA1421 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 15794891 Common - hypothetical protein NMA2011 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15794199 Common - cell-division protein NMA1266 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15795001 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase NMA2130 199 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 15794980 Common - transcriptional regulator CysB-like protein NMA2106 190 COG0583 LysR, Transcriptional regulator Transcription 15794156 Pathogen - hypothetical protein NMA1214 1 None None None 15793336 Common mafB adhesin NMA0324 2 None None None 15793136 Common infA translation initiation factor IF-1 NMA0108 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 15795004 Common - periplasmic hypothetical protein NMA2133 16 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 15793599 Common pilC1 pilus-associated protein NMA0609 29 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 15794699 Pathogen - hypothetical protein NMA1809 1 None None None 15794765 Pathogen - small secreted protein NMA1877 1 None None None 15794800 Common - DNA transport competence protein NMA1915 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 15793843 Common - hypothetical protein NMA0874 89 COG2835 COG2835, Uncharacterized conserved protein Function unknown 15794402 Pathogen - hypothetical protein NMA1503 1 None None None 15794116 Pathogen - hypothetical protein NMA1171 1 None None None 15793043 Common nuoH NADH dehydrogenase I chain H NMA0009 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 15794749 Pathogen - hypothetical protein NMA1861 1 None None None 15793844 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase NMA0875 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 15794028 Pathogen - hypothetical protein NMA1080 1 None None None 15794911 Common - secreted protein NMA2031 4 None None None 15795082 Common recQ ATP-dependent DNA helicase NMA2213 220 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 15794438 Common uvrB excinuclease ABC subunit B NMA1545 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 15793703 Common - pilin NMA0726 58 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 15793625 Common pglD pilin glycosylation protein NMA0637 154 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15793957 Common pgm phosphoglucomutase NMA1001 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15793390 Common - hypothetical protein NMA0382 104 COG0327 COG0327, Uncharacterized conserved protein Function unknown 15793756 Pathogen - hypothetical protein NMA0781 1 None None None 15793610 Common tyrS tyrosyl-tRNA synthetase NMA0620 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793803 Common - glycosyl transferase NMA0832 30 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15793131 Common rpoA DNA-directed RNA polymerase subunit alpha NMA0103 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 15793767 Common trmD tRNA (guanine-N1)-methyltransferase NMA0793 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 15794180 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit NMA1245 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 15794675 Common - hypothetical protein NMA1782 7 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 15794065 Common lst CMP-N-acetylneuraminate-beta-galactosamide-alpha- 2,3-sialyltransferase NMA1118 6 None None None 15794209 Common - hypothetical protein NMA1279 97 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15794868 Common - hypothetical protein NMA1986 74 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 15794242 Common - hypothetical protein NMA1313 12 None None None 15793084 Pathogen - hypothetical protein NMA0053 1 None None None 15795018 Common gloA lactoylglutathione lyase NMA2147 134 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 15793891 Common rplT 50S ribosomal protein L20 NMA0932 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 15793524 Common lgtB2 lacto-N-neotetraose biosynthesis glycosyl tranferase NMA0527 17 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 15793115 Common - hypothetical protein NMA0086 60 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 15794339 Common - recombination factor protein RarA NMA1433 241 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 15793415 Common ubiG 3-demethylubiquinone-9 3-methyltransferase NMA0410 174 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 15793196 Common - hypothetical protein NMA0169 31 COG0456 RimI, Acetyltransferases General function prediction only 15794169 Pathogen - hypothetical protein NMA1227 1 None None None 15794351 Common - periplasmic protein NMA1446 6 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 15794630 Common rpoD RNA polymerase sigma factor RpoD NMA1737 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15794358 Common - DNA modification methylase NMA1453 131 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15793487 Common - periplasmic transport protein NMA0488 72 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 15794456 Common - SUN-family protein NMA1563 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 15794075 Common - cytosine deaminase NMA1129 221 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 15794163 Common - phage integrase NMA1221 81 COG0582 XerC, Integrase DNA replication, recombination, and repair 15793941 Common - hypothetical protein NMA0984 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 15794423 Pathogen - hypothetical protein NMA1529 1 None None None 15794963 Common nadC nicotinate-nucleotide pyrophosphorylase NMA2088 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 15793632 Common - hypothetical protein NMA0646 77 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 15793526 Common - hypothetical protein NMA0529 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 15793533 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III NMA0538 225 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 15794014 Common hisS histidyl-tRNA synthetase NMA1065 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793387 Common rpsI 30S ribosomal protein S9 NMA0379 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 15794649 Common - peptidyl-prolyl isomerase NMA1756 130 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 15793511 Common atpB F0F1 ATP synthase subunit A NMA0513 191 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 15793078 Common - transmembrane transport protein NMA0047 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15793440 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein NMA0435 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 15794382 Common - acyl-CoA synthetase NMA1482 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15793567 Common - hypothetical protein NMA0576 34 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 15794211 Common - DNA-binding protein NMA1282 3 None None None 15793995 Common - DNA-binding protein NMA1039 60 COG3943 COG3943, Virulence protein General function prediction only 15794083 Common rpmJ 50S ribosomal protein L36 NMA1137 60 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 15793488 Pathogen - hypothetical protein NMA0489 1 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 15794148 Pathogen - hypothetical protein NMA1204 1 None None None 15793777 Common tatC sec-independent protein translocase component NMA0803 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 15793380 Pathogen - hypothetical protein NMA0372 1 None None None 15794399 Common - type-II restriction endonuclease NMA1499 14 None None None 15793839 Common maeA malate oxidoreductase NMA0870 202 COG0281 SfcA, Malic enzyme Energy production and conversion 15795060 Common ffh signal recognition particle protein NMA2190 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 15793690 Common - membrane protein NMA0712 54 COG1238 COG1238, Predicted membrane protein Function unknown 15793397 Common hpt hypoxanthine-guanine phosphoribosyltransferase NMA0389 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 15793617 Common - hypothetical protein NMA0630 21 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 15793665 Pathogen - hypothetical protein NMA0684 1 None None None 15793901 Common bioD dithiobiotin synthetase NMA0943 156 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 15793836 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase NMA0867 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 15793925 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase NMA0968 189 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 15793454 Common - inner membrane transport protein NMA0451 189 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 15793687 Common - integral membrane protein NMA0709 54 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 15794124 Common serB phosphoserine phosphatase NMA1179 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15793592 Common carB carbamoyl phosphate synthase large subunit NMA0602 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15793693 Common - hypothetical protein NMA0716 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 15793273 Common ftsX ABC transporter integral membrane protein NMA0255 111 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 15793479 Common - outer membrane peptidase NMA0478 76 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 15794816 Pathogen - integral membrane protein NMA1933 1 None None None 15793056 Common - IS1016 transposase NMA0022 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794440 Common - hypothetical protein NMA1547 144 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 15794791 Common alr alanine racemase NMA1906 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 15793200 Pathogen - hypothetical protein NMA0172 1 None None None 15793824 Pathogen - hypothetical protein NMA0854 1 None None None 15793174 Common rplK 50S ribosomal protein L11 NMA0146 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 15794196 Common - hypothetical protein NMA1263 167 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15794580 Common - glutamate dehydrogenase NMA1687 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 15794620 Common rfaF ADP-heptose:LPS heptosyltransferase II NMA1727 111 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15794570 Pathogen - hypothetical protein NMA1677a 1 None None None 15794700 Pathogen - hypothetical protein NMA1810 1 None None None 15793583 Common hemL glutamate-1-semialdehyde aminotransferase NMA0592 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 15794882 Pathogen - hypothetical protein NMA2002 1 None None None 15793303 Common - hydrolase NMA0286 74 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15793717 Common ubiB putative ubiquinone biosynthesis protein UbiB NMA0741 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 15793241 Common pilT pilus retraction protein NMA0218 215 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 15793212 Common - hypothetical protein NMA0184 68 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15793764 Common - ABC-transporter membrane protein NMA0790 169 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15793071 Pathogen - hypothetical protein NMA0039 1 None None None 15793502 Common - transglycosylase NMA0503 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15794589 Common gabD succinate semialdehyde dehydrogenase NMA1696 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15793236 Pathogen - hypothetical protein NMA0212 1 None None None 15793163 Common fusA elongation factor G NMA0135 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15794611 Common ackA1 acetate kinase NMA1718 162 COG0282 ackA, Acetate kinase Energy production and conversion 15794789 Pathogen - hypothetical protein NMA1904 1 None None None 15794477 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein NMA1584 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 15793883 Common lnt apolipoprotein N-acyltransferase NMA0918 153 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 15793798 Common - hypothetical protein NMA0827 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 15794469 Common nadE NH(3)-dependent NAD synthetase NMA1576 177 COG0171 NadE, NAD synthase Coenzyme metabolism 15794935 Common ftsZ cell division protein FtsZ NMA2057 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 15794894 Common - hypothetical protein NMA2014 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15793181 Pathogen - integral membrane protein NMA0154 1 None None None 15795021 Pathogen - hypothetical protein NMA2150 1 None None None 15793207 Pathogen - hypothetical protein NMA0179 1 None None None 15794952 Common - hypothetical protein NMA2076 94 COG1565 COG1565, Uncharacterized conserved protein Function unknown 15794997 Common - hypothetical protein NMA2126 60 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 15794715 Common - hypothetical protein NMA1825 12 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 15794063 Common icd isocitrate dehydrogenase NMA1116 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 15793315 Common - hypothetical protein NMA0301 3 None None None 15793626 Common pglC pilin glycosylation protein NMA0638a 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15794725 Pathogen - hypothetical protein NMA1835 3 None None None 15793226 Pathogen sacC capsule biosynthesis protein NMA0201 3 None None None 15795089 Common - hypothetical protein NMA2220 5 COG3212 COG3212, Predicted membrane protein Function unknown 15794332 Pathogen - hypothetical protein NMA1420 1 None None None 15793602 Common - periplasmic thioredoxin NMA0612 24 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 15794390 Common - oxidoreductase NMA1490 30 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 15793378 Common - integral membrane protein NMA0370 29 COG2056 COG2056, Predicted permease General function prediction only 15793913 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase NMA0956 219 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15794284 Common cysJ sulphite reductase alpha subunit NMA1363 105 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 15794272 Common - hypothetical protein NMA1350 182 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15794597 Common - hypothetical protein NMA1704 175 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 15794906 Common glr glutamate racemase NMA2026 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 15793453 Common - inner membrane transport protein NMA0450 104 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 15794183 Pathogen - hypothetical protein NMA1248 1 None None None 15794135 Pathogen - hypothetical protein NMA1191 1 None None None 15793469 Pathogen - lipoprotein NMA0467 1 None None None 15793733 Common gcvT glycine cleavage system aminomethyltransferase T NMA0758 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 15793103 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NMA0074 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15794560 Common - hypothetical protein NMA1666 77 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 15795091 Pathogen - hypothetical protein NMA2222 1 None None None 15793097 Pathogen - hypothetical protein NMA0068 2 None None None 15794081 Common - hypothetical protein NMA1135 73 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15793128 Common minD septum site-determining protein NMA0100 145 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 15795048 Common - hypothetical protein NMA2177 92 COG1981 COG1981, Predicted membrane protein Function unknown 15793851 Common - hypothetical protein NMA0882 115 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15793495 Common cad cadmium resistance protein NMA0496 19 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 15793997 Common - hypothetical protein NMA1046 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 15794709 Common - hypothetical protein NMA1819 82 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 15793546 Common dnaA chromosomal replication initiator protein NMA0552 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15793804 Common - hypothetical protein NMA0833 187 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 15794805 Common apt adenine phosphoribosyltransferase NMA1920 184 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15793090 Common - ferredoxin NMA0061 126 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 15793861 Common purF amidophosphoribosyltransferase NMA0892 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 15794344 Common - lipoprotein NMA1439 3 None None None 15793952 Common recB exodeoxyribonuclease V beta chain NMA0995 223 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 15794473 Common - ATP-dependent RNA helicase NMA1580 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15793938 Common - pilus biogenesis protein NMA0981 32 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 15794834 Common - hypothetical protein NMA1951 40 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 15794752 Common - hypothetical protein NMA1864 4 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15793197 Pathogen - lipoprotein NMA0170 1 None None None 15794556 Common - hypothetical protein NMA1662 77 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 15794101 Common - hypothetical protein NMA1155a 31 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794250 Common - hypothetical protein NMA1323 28 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 15795034 Common rpmA 50S ribosomal protein L27 NMA2163 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 15793553 Common drg type II restriction endonuclease NMA0560 5 None None None 15794023 Pathogen - hypothetical protein NMA1075 1 None None None 15794654 Common acnB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase NMA1761 217 COG1049 AcnB, Aconitase B Energy production and conversion 15794971 Common - membrane pump-driving ATPase NMA2096 20 None None None 15793279 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase NMA0261 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 15794240 Pathogen - hypothetical protein NMA1311 1 None None None 15794873 Common relA GTP pyrophosphokinase NMA1991 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 15793036 Common nuoL NADH dehydrogenase subunit L NMA0002 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 15793492 Common - periplasmic protein NMA0493 156 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15793571 Common argA N-acetylglutamate synthase NMA0580 199 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 15794007 Common - hypothetical protein NMA1058 7 None None None 15794815 Common - lipase NMA1932 107 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 15794569 Common - hypothetical protein NMA1675 37 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793509 Common - IS1655 transposase NMA0511 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 15794039 Common lolB outer membrane lipoprotein LolB NMA1091 31 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 15794732 Common - hypothetical protein NMA1843 6 COG5003 COG5003, Mu-like prophage protein gp37 General function prediction only 15793984 Pathogen - DNA-binding protein NMA1028 1 None None None 15794578 Common - tautomerase NMA1685 32 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 15793783 Common - hypothetical protein NMA0810 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 15794235 Pathogen - hypothetical protein NMA1306 1 None None None 15794048 Common cysU sulphate permease inner membrane protein NMA1100 232 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 15794307 Common - hypothetical protein NMA1394 10 COG3737 COG3737, Uncharacterized conserved protein Function unknown 15793812 Common fbpC iron-uptake permease ATP-binding protein NMA0842 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15794945 Pathogen - periplasmic protein NMA2067 1 None None None 15794088 Common lpdA2 dihydrolipoamide dehydrogenase NMA1142 236 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15793538 Common rpmF 50S ribosomal protein L32 NMA0544 111 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 15793188 Common - hypothetical protein NMA0161 20 None None None 15793743 Common - IS1655 transposase NMA0768 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 15793965 Common - hypothetical protein NMA1009 91 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 15794095 Common kgd alpha-ketoglutarate decarboxylase NMA1149 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 15793838 Common tdk thymidylate kinase NMA0869 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 15794994 Pathogen - hypothetical protein NMA2122 1 None None None 15795016 Common - morphogene NMA2145 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 15794218 Pathogen - hypothetical protein NMA1289 1 None None None 15794142 Common - DNA-binding protein NMA1198 7 None None None 15793810 Common hisH imidazole glycerol phosphate synthase subunit HisH NMA0840 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 15794670 Common - integral membrane protein NMA1777 8 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15794165 Common - hypothetical protein NMA1223 7 COG1414 IclR, Transcriptional regulator Transcription 15794846 Common thyA thymidylate synthase NMA1963 145 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 15793535 Pathogen - hypothetical protein NMA0541 1 None None None 15794221 Pathogen - hypothetical protein NMA1292 1 None None None 15794200 Common proA gamma-glutamyl phosphate reductase NMA1267 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 15793552 Common leuS leucyl-tRNA synthetase NMA0559 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15794603 Common - nuclease NMA1710 67 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 15794635 Common pyrG CTP synthetase NMA1742 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 15793691 Common - transmembrane hexose transporter NMA0714 56 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 15793975 Common - hypothetical protein NMA1019 48 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15793928 Pathogen - lipoprotein NMA0971 1 None None None 15794205 Common - hypothetical protein NMA1274 27 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 15793564 Common - hypothetical protein NMA0573 130 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15793680 Common rbn ribonuclease BN/unknown domain fusion protein NMA0700 75 COG1295 Rbn, Predicted membrane protein Function unknown 15794826 Common serS seryl-tRNA synthetase NMA1943 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793663 Pathogen - lipoprotein NMA0680 1 None None None 15794690 Common - hypothetical protein NMA1799 10 COG4128 Zot, Zonula occludens toxin General function prediction only 15793959 Common - transmembrane transport protein NMA1003 132 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15794323 Pathogen - hypothetical protein NMA1411 1 None None None 15794066 Common - C-type cytochrome NMA1119 15 COG3909 COG3909, Cytochrome c556 Energy production and conversion 15794658 Common ilvH acetolactate synthase isozyme III small subunit NMA1765 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 15794367 Common - hypothetical protein NMA1465 166 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15794607 Common dnaQ DNA polymerase III, epsilon chain NMA1714 180 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15793386 Common rplM 50S ribosomal protein L13 NMA0378 218 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 15793559 Pathogen - hypothetical protein NMA0568 1 None None None 15793594 Common - hypothetical protein NMA0604 25 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 15794874 Common natC periplasmic type I secretion system protein NMA1994 107 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15793627 Common pglB pilin glycosylation protein NMA0639 196 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 15793198 Common - hypothetical protein NMA0171 2 None None None 15793660 Pathogen - hypothetical protein NMA0677 1 None None None 15795023 Common fabI enoyl-(acyl carrier protein) reductase NMA2152 230 COG0623 FabI, Enoyl- acyl-carrier-protein 15793243 Common - integral membrane protein NMA0220 55 COG1289 COG1289, Predicted membrane protein Function unknown 15794918 Common recO DNA repair protein (recombination protein o) NMA2038 62 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15794640 Common gshB glutathione synthetase NMA1747 133 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 15794361 Common aspA aspartate ammonia-lyase NMA1459 225 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 15794632 Common lbpA lactoferrin binding protein A NMA1739 61 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15793852 Pathogen - lipoprotein NMA0883 1 None None None 15795093 Common - ribosome-associated GTPase NMA2224 164 COG1162 COG1162, Predicted GTPases General function prediction only 15793251 Common - hypothetical protein NMA0229 13 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 15794274 Pathogen - lipoprotein NMA1353 1 None None None 15793932 Common - integral membrane protein NMA0975 67 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15794297 Common bfrB bacterioferritin B NMA1376 97 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 15793831 Common - hypothetical protein NMA0861 193 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15795062 Common - hypothetical protein NMA2192 12 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15794486 Common - hypothetical protein NMA1593 138 COG1959 COG1959, Predicted transcriptional regulator Transcription 15794862 Common - cytochrome c oxidase subunit NMA1980 143 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 15794017 Pathogen - hypothetical protein NMA1068 1 None None None 15794454 Common - hypothetical protein NMA1561 7 COG3782 COG3782, Uncharacterized protein conserved in bacteria Function unknown 15794612 Common dipZ thiol:disulfide interchange protein precursor NMA1719 109 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 15793121 Common dadA D-amino acid dehydrogenase small subunit NMA0092 137 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15794259 Common - periplasmic protein NMA1334 11 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 15794516 Pathogen - hypothetical protein NMA1622 1 None None None 15793771 Common - two-component system sensor kinase NMA0797 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15793701 Common - hypothetical protein NMA0724 183 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15793178 Common - ferredoxin NMA0150 123 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15794950 Common mraW S-adenosyl-methyltransferase MraW NMA2074 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 15793130 Common rplQ 50S ribosomal protein L17 NMA0102 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 15794502 Common pgl 6-phosphogluconolactonase NMA1608 122 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 15794900 Common - integral membrane protein NMA2020 77 COG2928 COG2928, Uncharacterized conserved protein Function unknown 15793462 Common - hypothetical protein NMA0459 11 COG3177 COG3177, Uncharacterized conserved protein Function unknown 15794942 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NMA2064 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15793416 Common thrB homoserine kinase NMA0411 68 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 15794359 Common leuB 3-isopropylmalate dehydrogenase NMA1456 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 15794383 Common - transmembrane transport protein NMA1483 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 15794460 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C NMA1567 121 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 15794419 Common clpP endopeptidase NMA1525 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15794042 Common - 50S ribosomal protein L25/general stress protein Ctc NMA1094 195 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 15794154 Pathogen - hypothetical protein NMA1210 1 None None None 15793970 Pathogen - hypothetical protein NMA1014 1 None None None 15793083 Common - integral membrane protein NMA0052 61 COG1971 COG1971, Predicted membrane protein Function unknown 15793280 Common gnd 6-phosphogluconate dehydrogenase NMA0262 149 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 15793426 Common coaD phosphopantetheine adenylyltransferase NMA0421 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 15793742 Common - hypothetical protein NMA0767 21 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15794937 Common ftsQ cell division protein NMA2059 82 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 15794835 Common - hypothetical protein NMA1952 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 15794236 Pathogen - hypothetical protein NMA1307 1 None None None 15793903 Common ubiA 4-hydroxybenzoate octaprenyltransferase NMA0945 167 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15793237 Common dksA DnaK suppressor protein NMA0213 146 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15794429 Common priB primosomal replication protein NMA1536 15 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 15793841 Common lpxK tetraacyldisaccharide 4'-kinase NMA0872 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 15794121 Common - membrane protein NMA1176 24 COG3686 COG3686, Predicted membrane protein Function unknown 15794794 Common - hypothetical protein NMA1908 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 15794153 Pathogen - hypothetical protein NMA1209 1 None None None 15793896 Common himA integration host factor alpha-subunit NMA0938 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 124054302 Common - glycerate dehydrogenase NMA0274 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15793874 Common rluD ribosomal large subunit pseudouridine synthase D NMA0908 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15793294 Common glmS D-fructose-6-phosphate amidotransferase NMA0276 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 15793334 Pathogen - hypothetical protein NMA0322 1 None None None 15794582 Common recX recombination regulator RecX NMA1689 49 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 15794312 Common - hypothetical protein NMA1400 104 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15794907 Common - hypothetical protein NMA2027 204 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 15794370 Common ppiA peptidyl-prolyl cis-trans isomerase A NMA1469 195 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 15794058 Common - hypothetical protein NMA1111 90 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 15794467 Common - integral membrane transporter NMA1574 88 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 15795084 Common - hypothetical protein NMA2215 46 None None None 15793275 Common pgk phosphoglycerate kinase NMA0257 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 15793619 Common dnaE DNA polymerase III, alpha subunit NMA0632 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 15793750 Pathogen - integral membrane protein NMA0775 1 None None None 15793342 Common - hypothetical protein NMA0330 153 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 15793317 Common - hypothetical protein NMA0304 139 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 15795007 Common tal transaldolase NMA2136 115 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15793689 Common nth endonuclease III NMA0711 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 15795002 Common - ABC transporter ATP-binding protein NMA2131 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 15793310 Common - periplasmic protein NMA0295 92 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 15794392 Common panD aspartate alpha-decarboxylase NMA1492 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 15793142 Common rplF 50S ribosomal protein L6 NMA0114 236 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 15794377 Common - mercuric ion binding protein NMA1476 110 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 15793719 Common grpE heat shock protein NMA0744 220 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15794730 Common - hypothetical protein NMA1841 21 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 15794553 Common aroD 3-dehydroquinate dehydratase NMA1659 54 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 15794078 Common - hypothetical protein NMA1132 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 15794319 Common - peptidyl-prolyl cis-trans isomerase NMA1407 110 None None None 15794480 Common - hypothetical protein NMA1587 2 None None None 15793481 Pathogen - hypothetical protein NMA0481 1 None None None 15794053 Pathogen - hypothetical protein NMA1106 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 15794051 Common sodB superoxide dismutase NMA1104 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 15794503 Common zwf glucose-6-phosphate 1-dehydrogenase NMA1609 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 15793405 Common thiC thiamine biosynthesis protein ThiC NMA0397 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 15795040 Common emrA multidrug resistance translocase NMA2169 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15794669 Common - insertion element IS1106A3 transposase NMA1776 35 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15794288 Common cysG sirohaem synthase NMA1367 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 15794534 Common - aminopeptidase NMA1640 202 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15793634 Common aroK shikimate kinase NMA0648 201 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 15793449 Common purL phosphoribosylformylglycinamidine synthase NMA0445 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 15793675 Pathogen - hypothetical protein NMA0695 1 None None None 15794854 Common mtrR transcriptional regulato NMA1971 122 COG1309 AcrR, Transcriptional regulator Transcription 15795075 Common - rotamase NMA2206 163 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15793113 Common - integral membrane protein NMA0084 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15793149 Common rpmC 50S ribosomal protein L29 NMA0121 143 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 15794111 Pathogen - hypothetical protein NMA1165 1 None None None 15794027 Pathogen - hypothetical protein NMA1079 1 None None None 15794861 Common - cytochrome oxidase subunit NMA1979 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 15793659 Common argC N-acetyl-gamma-glutamyl-phosphate reductase NMA0676 218 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 15793966 Pathogen - hypothetical protein NMA1010 1 None None None 15794652 Common - hypothetical protein NMA1759 90 COG0795 COG0795, Predicted permeases General function prediction only 15793445 Common - hypothetical outer membrane protein NMA0440 140 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15794493 Pathogen - transposase NMA1600 3 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794071 Common dapA dihydrodipicolinate synthase NMA1124 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15794104 Pathogen - hypothetical protein NMA1158 1 None None None 15793513 Common atpF ATP synthase B chain NMA0515 77 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 15793738 Common - ABC-transporter ATP-binding protein NMA0763 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15793920 Common - hypothetical protein NMA0963 205 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15794238 Pathogen - hypothetical protein NMA1309 1 None None None 15793408 Common - hypothetical protein NMA0401 3 COG2336 MazE, Growth regulator Signal transduction mechanisms 15793261 Common - lipopolysaccharide heptosyltransferase I NMA0243 79 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15794540 Common - phopholipase D-family protein NMA1646 148 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15794728 Common - hypothetical DNA-binding protein NMA1838 6 COG1396 HipB, Predicted transcriptional regulators Transcription 15795066 Common - LysR-family transcriptional regulator NMA2197 162 COG0583 LysR, Transcriptional regulator Transcription 15793549 Common ppk polyphosphate kinase NMA0555 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 15794029 Pathogen - membrane protein NMA1081 1 None None None 15794130 Common - hypothetical protein NMA1186 15 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 15793885 Pathogen - hypothetical protein NMA0926 1 None None None 15793483 Common - transcriptional regulator NMA0483 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15793395 Common - hydrolase NMA0387 219 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15793759 Pathogen - hypothetical protein NMA0784 1 None None None 15794305 Common ung uracil-DNA glycosylase NMA1384 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 15793644 Common - membrane protein NMA0660 187 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 15794002 Common recJ single-stranded-DNA-specific exonuclease NMA1052 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15794020 Pathogen - hypothetical protein NMA1072 1 None None None 15793220 Common ctrD capsule polysaccharide export ATP-binding protein NMA0195 248 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15794549 Common mutL DNA mismatch repair protein NMA1655 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 15793291 Common fbp peptidyl-prolyl cis-trans isomerase NMA0273 154 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 15793816 Common - hypothetical protein NMA0846 2 None None None 15794264 Common hscA chaperone protein HscA NMA1340 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15793109 Common frr ribosome recycling factor NMA0080 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 15794009 Common dcd deoxycytidine triphosphate deaminase NMA1060 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 15793257 Common - hypothetical protein NMA0239 3 None None None 15793653 Common - two-component system sensor kinase NMA0670 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15794313 Common recD exodeoxyribonuclease V alpha subunit NMA1401 127 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 15793455 Common fetB membrane transport solute-binding protein NMA0452 63 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 15793741 Common - electron transfer flavoprotein-ubiquinone oxidoreductase NMA0766a 112 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15794775 Common aniA nitrite reductase, major outer membrane copper-containing protein NMA1887 72 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 15793300 Common phnA PhnA protein ortholog NMA0283 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 15793781 Common hisE phosphoribosyl-ATP cyclohydrolase NMA0807 181 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 15794283 Common cysI sulphite reductase beta subunit NMA1362 145 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 15793168 Pathogen - hypothetical protein NMA0140 1 None None None 15793620 Pathogen - hypothetical protein NMA0632a 1 None None None 15794825 Common - dinucleoside polyphosphate hydrolase NMA1942 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15793467 Common - hypothetical inner membrane protein NMA0465 117 COG2855 COG2855, Predicted membrane protein Function unknown 15794189 Common ggt gamma-glutamyltranspeptidase NMA1255 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 15793301 Common glmU UDP-N-acetylglucosamine pyrophosphorylase NMA0284 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 15794784 Common - integral membrane protein NMA1899 9 None None None 15793744 Common - IS1016 transposase NMA0769 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793439 Common - hypothetical protein NMA0434 138 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 15795035 Common - hypothetical protein NMA2164 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 15794712 Common - hypothetical protein NMA1822 6 None None None 15794256 Pathogen - hypothetical protein NMA1329 2 None None None 15794923 Common - oxidoreductase NMA2045 162 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 15795045 Common - hypothetical protein NMA2174 12 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15794550 Common dnaZX DNA polymerase III subunits gamma and tau NMA1656 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15793866 Common - hypothetical protein NMA0899 6 None None None 15793100 Common rne ribonuclease E NMA0071 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 15794988 Common - hypothetical protein NMA2115 13 None None None 15794322 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase NMA1410 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15793736 Common - regulatory protein NMA0761 25 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 15793707 Common priA primosome assembly protein PriA NMA0731 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 15794517 Pathogen - hypothetical protein NMA1623 2 None None None 15795070 Common - hypothetical protein NMA2201 22 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 15793573 Common pyrE orotate phosphoribosyltransferase NMA0582 108 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 15793360 Pathogen - integral membrane protein NMA0349 1 None None None 15793357 Common - ATP-binding protein NMA0346 12 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 15793800 Common - hypothetical protein NMA0829 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 15794787 Common - hypothetical protein NMA1902 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 15794193 Common - hypothetical protein NMA1260 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 15794329 Common - molybdopterin-guanine dinucleotide biosynthesis protein A NMA1417 64 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 15794642 Common glpR glycerol 3-phosphate regulon repressor NMA1749 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15793505 Common - lipoprotein NMA0506 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 15794114 Pathogen - hypothetical protein NMA1169 1 None None None 15794965 Common nadA quinolinate synthetase NMA2090 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 15793544 Common rnpA ribonuclease P NMA0550 45 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 15793266 Common - acetyltransferase NMA0248 21 COG3153 COG3153, Predicted acetyltransferase General function prediction only 15794767 Pathogen - hypothetical protein NMA1879 1 None None None 15794896 Common speB agmatinase NMA2016 153 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 15794870 Common - integral membrane protein NMA1988 99 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 15793423 Common - hypothetical protein NMA0418 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 15794064 Pathogen - hypothetical protein NMA1117 1 None None None 15794170 Common - hypothetical protein NMA1228 2 None None None 15794813 Common - lipoprotein NMA1930 19 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 15795058 Pathogen - hypothetical protein NMA2188 1 None None None 15793052 Common nuoB NADH dehydrogenase subunit B NMA0018 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 15793855 Common ribH riboflavin synthase subunit beta NMA0886 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 15794880 Common - hypothetical protein NMA2000 5 None None None 15793609 Common - lipopolysaccharide modification acyltransferase NMA0619 107 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 15794470 Common - hypothetical protein NMA1577 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 15794592 Pathogen - hypothetical protein NMA1699 5 COG2879 COG2879, Uncharacterized small protein Function unknown 15793826 Common - hypothetical protein NMA0856 2 None None None 15794801 Common - hypothetical protein NMA1916 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 15793773 Pathogen - hypothetical protein NMA0799 1 None None None 15794707 Common rnhA ribonuclease HI NMA1817 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 15793054 Common - hypothetical protein NMA0020 30 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 15794999 Common glnA glutamine synthetase NMA2128 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 15794810 Common hemO haem utilisation protein NMA1927 12 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 15793219 Common - transcriptional accessory protein NMA0194 177 COG2183 Tex, Transcriptional accessory protein Transcription 15793099 Common rluC ribosomal large subunit pseudouridine synthase C NMA0070 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15793728 Common - membrane protein NMA0753 29 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 15793809 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase NMA0839 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 15793939 Common - hypothetical protein NMA0982 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15794992 Pathogen - hypothetical protein NMA2120 1 None None None 15794841 Common lgtF beta-1,4-glucosyltransferase NMA1958 144 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15794738 Common - hypothetical protein NMA1850 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 15794723 Common - hypothetical DNA-binding protein NMA1833 20 None None None 15794567 Common - integral membrane transporter NMA1673 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15794572 Common ppx/gppA exopolyphosphatase NMA1679 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 15793982 Pathogen - hypothetical protein NMA1026 1 None None None 15793388 Pathogen - hypothetical protein NMA0380 1 None None None 15794010 Common - periplasmic protein NMA1061 3 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 15793206 Common - hypothetical protein NMA0178 69 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 15793731 Common - AsnC-family transcriptional regulator NMA0756 167 COG1522 Lrp, Transcriptional regulators Transcription 15793720 Common - periplasmic protein NMA0745 26 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 15794884 Pathogen - hypothetical protein NMA2004 1 None None None 15793308 Common pilA signal recognition particle protein NMA0291 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 15794681 Common - hypothetical protein NMA1789 2 None None None 15793038 Common - hypothetical protein NMA0004 30 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 15794019 Pathogen - hypothetical protein NMA1071 1 None None None 15793218 Common galE2' truncated UDP-glucose 4-epimerase NMA0190 196 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 15794524 Common - lipid A biosynthesis lauroyl acyltransferase NMA1630 109 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 15794744 Pathogen - hypothetical protein NMA1856 1 None None None 15793092 Common aat leucyl/phenylalanyl-tRNA--protein transferase NMA0063 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 15793073 Pathogen - hypothetical protein NMA0041 1 None None None 15794755 Common - hypothetical protein NMA1867 17 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 15793871 Common iga IgA1 protease NMA0905 14 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15793081 Common katA catalase NMA0050 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 15793868 Common ksgA dimethyladenosine transferase NMA0902 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 15794061 Common - hypothetical protein NMA1114 77 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 15794981 Common - anaerobic transcriptional regulatory protein NMA2107 155 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15793460 Common iga2 IgA-specific serine endopeptidase NMA0457 7 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15794916 Pathogen - hypothetical protein NMA2036 1 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 15794252 Pathogen - phage tail fibre protein NMA1325 3 None None None 15793670 Common - hypothetical protein NMA0690 9 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 15794500 Common - transcriptional regulator NMA1605 131 COG1737 RpiR, Transcriptional regulators Transcription 15793833 Common - coproporphyrinogen III oxidase NMA0864 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15794295 Common glnD [protein-PII] uridylyltransferase NMA1374 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 15794864 Common - hypothetical protein NMA1982 41 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 15794068 Common - acyl-CoA hydrolase NMA1121 131 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 15794257 Common - hypothetical protein NMA1330 4 None None None 15794488 Pathogen - hypothetical protein NMA1595 1 None None None 15794637 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase NMA1744 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 15793696 Common aspC aromatic amino acid aminotransferase NMA0719 72 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15794719 Common - hypothetical protein NMA1829 20 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 15793152 Common rplV 50S ribosomal protein L22 NMA0124 224 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 15794216 Pathogen - hypothetical protein NMA1287 1 None None None 15794532 Common lysS lysyl-tRNA synthetase NMA1638 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15794348 Pathogen - hypothetical protein NMA1443 1 None None None 15793910 Pathogen - hypothetical protein NMA0953 1 None None None 15795071 Common - inner membrane trans-acylase protein NMA2202 93 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 15793147 Common rplN 50S ribosomal protein L14 NMA0119 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 15793763 Common - periplasmic binding protein NMA0789 165 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15794508 Common mutY adenine glycosylase NMA1614 230 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 15794353 Common radC DNA repair protein RadC NMA1448 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 15793245 Common - peptide transporter NMA0222 77 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 15794679 Common - polyamine permease substrate-binding protein NMA1786 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15794412 Common adhC alcohol dehydrogenase class-III NMA1518 198 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 15794996 Pathogen - outer membrane hypothetical protein NMA2124 1 None None None 15793410 Common - hypothetical protein NMA0403 139 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 15794325 Common rpe ribulose-phosphate 3-epimerase NMA1413 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 15794261 Common - short chain dehydrogenase NMA1336 187 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15794034 Common - hypothetical protein NMA1086 77 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 15793140 Common rpsE 30S ribosomal protein S5 NMA0112 238 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 15793159 Pathogen - hypothetical protein NMA0132 3 COG3596 COG3596, Predicted GTPase General function prediction only 15794785 Common - haemolysin NMA1900 113 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 15793384 Common - hypothetical protein NMA0376 2 None None None 15793557 Common - hypothetical protein NMA0565 27 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 15793451 Common - ABC transporter ATP-binding subunit NMA0448 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 15794144 Common - surface fibril protein NMA1200 30 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 15793379 Common slyX hypothetical protein NMA0371 8 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 15794645 Pathogen - hypothetical protein NMA1752 1 None None None 15794223 Pathogen - hypothetical protein NMA1294 1 None None None 15794546 Common - periplasmic protein NMA1652 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 15793550 Pathogen - periplasmic protein NMA0556 1 None None None 15794848 Common - GntR-family transcriptional regulator NMA1965 128 COG2186 FadR, Transcriptional regulators Transcription 15794601 Common - hypothetical protein NMA1708 4 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15793532 Common - integral membrane protein NMA0537 56 COG3326 COG3326, Predicted membrane protein Function unknown 15793253 Pathogen - lipoprotein NMA0233 2 None None None 15794372 Common - cation uptake regulator NMA1471 72 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15793191 Common def peptide deformylase NMA0164 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 15793747 Common - DNA-invertase NMA0772 70 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793682 Common - hypothetical protein NMA0703 13 None None None 15793786 Common secF preprotein translocase subunit SecF NMA0813 214 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 15794106 Common - phosphatidylserine decarboxylase NMA1160 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 15795056 Pathogen - hypothetical protein NMA2186 1 None None None 15793933 Common lepB signal peptidase I NMA0976 204 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15794401 Common nrdA ribonucleotide-diphosphate reductase subunit alpha NMA1501 205 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15793562 Common - hypothetical protein NMA0571 84 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 15794624 Common - hypothetical protein NMA1731 6 None None None 15794056 Common - membrane protein NMA1109 2 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 15793393 Common petC cytochrome C1 precursor NMA0385 78 COG2857 CYT1, Cytochrome c1 Energy production and conversion 15794692 Common gpm phosphoglyceromutase NMA1801 136 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 15794613 Common - hypothetical protein NMA1720 23 None None None 15794605 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NMA1712 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 15793063 Common - hypothetical protein NMA0030 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 15793629 Common - lipopolysaccharide biosynthesis translocase NMA0643 10 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15794268 Pathogen - hypothetical protein NMA1345 1 None None None 15794850 Pathogen - hypothetical protein NMA1967 1 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 15794495 Pathogen - transposase fragment NMA1601a 3 None None None 15793829 Common - transmembrane potassium transporter NMA0859 145 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15794510 Pathogen - hypothetical protein NMA1616 1 None None None 15794806 Common - hypothetical protein NMA1921 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15794444 Common - Holliday junction resolvase-like protein NMA1551 183 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 15793407 Common chpA PEMK-like protein NMA0400 52 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 15794341 Pathogen - hypothetical protein NMA1436 1 None None None 15794379 Common - periplasmic protein NMA1479 24 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 15794555 Common - impB/mucB/samB family protein NMA1661 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 15793964 Common ftsJ cell division protein NMA1008 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 15794496 Pathogen - transposase fragment NMA1601b 2 None None None 15793165 Common rpsL 30S ribosomal protein S12 NMA0137 234 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 15793111 Common cdsA phosphatidate cytidylyltransferase NMA0082 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 15793922 Common - ferredoxin NMA0965 21 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 15793133 Common rpsK 30S ribosomal protein S11 NMA0105 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 15794585 Common - membrane peptidase NMA1692 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15793447 Common - hypothetical inner membrane protein NMA0442 172 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 15793349 Common - lipoprotein NMA0339 53 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 15795077 Common - hypothetical protein NMA2208 91 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 15793657 Common secB preprotein translocase subunit SecB NMA0674 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 15793673 Pathogen - hypothetical protein NMA0693 5 None None None 15793905 Common - HPr kinase/phosphorylase NMA0947 70 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 15793734 Common gcvH glycine cleavage system protein H NMA0759 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 15793649 Common - IS1016 transposase NMA0664a 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794044 Common ilvA threonine dehydratase NMA1096 208 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 15794914 Common - hypothetical protein NMA2034 3 None None None 15794394 Common - hypothetical protein NMA1494 4 None None None 15793595 Common - hypothetical protein NMA0605 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 15794158 Pathogen - hypothetical protein NMA1216 1 None None None 15794770 Common - transposase NMA1882 22 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793847 Pathogen - hypothetical protein NMA0878 1 None None None 15793332 Pathogen - hypothetical protein NMA0320 1 None None None 15794451 Common - TonB-dependent receptor protein NMA1558 66 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15793347 Common map methionine aminopeptidase NMA0337 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 15793946 Common - hypothetical protein NMA0989 53 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 15794435 Common trmB tRNA (guanine-N(7))-methyltransferase NMA1542 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 15794410 Common hip integration host factor beta-subunit NMA1516 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15793435 Common - DNA helicase NMA0430 86 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 15794769 Common - hypothetical DNA-binding protein NMA1881 23 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 15793954 Common - amino acid permease substrate-binding protein NMA0997 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15794427 Common rplI 50S ribosomal protein L9 NMA1534 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 15794096 Common sucB dihydrolipoamide acetyltransferase NMA1150 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 15795086 Common - hypothetical protein NMA2217 167 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 15794287 Common cysH phosphoadenosine phosphosulfate reductase NMA1366 162 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15794246 Common - hypothetical protein NMA1319 4 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 15793792 Common - oxidoreductase NMA0819 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15793476 Pathogen hpuA haemoglobin-haptoglobin-utilization protein NMA0475 1 None None None 15794910 Common - hypothetical protein NMA2030 130 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 15795011 Common - D-tyrosyl-tRNA deacylase NMA2140 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 15793956 Common - amino acid permease ATP-binding protein NMA1000 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15794151 Common - hypothetical protein NMA1207 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15794310 Common hupB DNA-binding protein NMA1397 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15795000 Common aroE shikimate dehydrogenase NMA2129 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 15793848 Common trpA tryptophan synthase subunit alpha NMA0879 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 15794203 Common - hypothetical protein NMA1272 88 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 15793222 Common ctrB capsule polysaccharide export inner-membrane protein NMA0197 41 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 15793894 Pathogen - hypothetical protein NMA0936 1 None None None 15794777 Common - hypothetical protein NMA1891 74 COG0778 NfnB, Nitroreductase Energy production and conversion 15794836 Common - hypothetical protein NMA1953 7 COG4899 COG4899, Uncharacterized protein conserved in bacteria Function unknown 15793977 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase NMA1021 192 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 15793424 Common - hypothetical protein NMA0419 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 15793993 Common rfaD ADP-L-glycero-D-mannoheptose epimerase NMA1037 227 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15793248 Common - integral membrane protein NMA0226 5 COG2259 COG2259, Predicted membrane protein Function unknown 15794281 Pathogen - hypothetical protein NMA1360 1 None None None 15794565 Common - hypothetical protein NMA1671 34 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15794820 Common tyrB aromatic amino acid aminotransferase NMA1937 72 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15795030 Common pilF type IV pilus assembly protein NMA2159 211 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 15795031 Common - hypothetical protein NMA2160 28 COG2707 COG2707, Predicted membrane protein Function unknown 15794684 Pathogen - hypothetical protein NMA1793 2 None None None 15794618 Common - virulence associated protein NMA1725 14 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15795037 Common rpmB 50S ribosomal protein L28 NMA2166 170 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 15794085 Common metF 5,10-methylenetetrahydrofolate reductase NMA1139 145 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 15795043 Common - hypothetical protein NMA2172 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15794838 Common - hypothetical protein NMA1955 2 None None None 15793362 Common - aspartate-semialdehyde dehydrogenase NMA0351 196 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15794975 Common - integral membrane transport protein NMA2100 29 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15793355 Common - truncated IS1016 transposase NMA0344A 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794930 Common acnA aconitate hydratase NMA2052 223 COG1048 AcnA, Aconitase A Energy production and conversion 15794187 Common - IS1106A3 transposase NMA1253 40 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15793282 Common pilE fimbrial protein precursor (pilin) NMA0264 30 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 15793465 Common - S-ribosylhomocysteinase NMA0463 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 15793047 Pathogen - hypothetical protein NMA0013 2 None None None 15793709 Common - transposase NMA0733 53 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793194 Common pyrI aspartate carbamoyltransferase regulatory subunit NMA0167 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 15794590 Pathogen - lipoprotein NMA1697 2 None None None 15793049 Common nuoE NADH dehydrogenase subunit E NMA0015 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 15795013 Common - periplasmi hypothetical protein NMA2142 47 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15794650 Common holC DNA polymerase III chi subunit NMA1757 30 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 15793496 Common - inner membrane protein NMA0497 19 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 15793570 Common - prolyl endopeptidase NMA0579 113 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 15793325 Pathogen mafB' MAFB alternative C-terminus NMA0313 1 None None None 15793988 Common adk adenylate kinase NMA1032 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 15793231 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase NMA0206 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 15794254 Common - hypothetical protein NMA1327 12 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 15793107 Pathogen - integral membrane protein NMA0078 1 None None None 15793991 Common nmgII modification methylase NMA1035 133 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15794683 Common - hypothetical protein NMA1792 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 15794303 Common - periplasmic protein NMA1382 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15793515 Common atpA F0F1 ATP synthase subunit alpha NMA0517 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 15793542 Common - putative inner membrane protein translocase component YidC NMA0548 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 15794175 Pathogen - hypothetical protein NMA1233 1 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 15794244 Common - hypothetical protein NMA1315 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 15793068 Common - hypothetical protein NMA0036 2 None None None 15793061 Common - hypothetical protein NMA0028 100 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 15793040 Common nuoJ NADH dehydrogenase I chain J NMA0006 62 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 15793972 Common - RNA-binding protein NMA1016 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15793806 Common prfC peptide chain release factor 3 NMA0836 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 15793125 Pathogen - hypothetical protein NMA0096 1 None None None 15794231 Common - hypothetical protein NMA1302 6 None None None 15793647 Common metK S-adenosylmethionine synthetase NMA0663 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 15794831 Common - DedA-family integral membrane protein NMA1948 146 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15793814 Common fbpA major ferric iron binding protein NMA0844 114 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 15794266 Common - hypothetical protein NMA1343 8 COG3779 COG3779, Uncharacterized protein conserved in bacteria Function unknown 15793457 Common trmE tRNA modification GTPase TrmE NMA0454 220 COG0486 ThdF, Predicted GTPase General function prediction only 15794887 Common - hypothetical protein NMA2007 2 None None None 15794705 Common thiD phosphomethylpyrimidine kinase NMA1815 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 15793146 Common rplX 50S ribosomal protein L24 NMA0118 168 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 15794128 Pathogen - hypothetical protein NMA1183 1 None None None 15793442 Common - hypothetical inner membrane protein NMA0437 64 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 15793421 Common - hypothetical protein NMA0416 187 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 15794004 Pathogen - periplasmic protein NMA1054 1 None None None 15793600 Pathogen - hypothetical protein NMA0610 1 None None None 15793184 Common - hypothetical protein NMA0157 28 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 15794527 Common - hypothetical protein NMA1633 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15794721 Common - hypothetical protein NMA1831 13 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 15794842 Common rfaK alpha 1,2 N-acetylglucosamine transferase NMA1959 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15793888 Common thrS threonyl-tRNA synthetase NMA0929 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15794823 Common - hypothetical protein NMA1940 5 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 15793306 Common - hypothetical protein NMA0289 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 161353792 Common edd phosphogluconate dehydratase NMA1610 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15793050 Common nuoD NADH dehydrogenase subunit D NMA0016 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 15794520 Common - RTX-family exoprotein NMA1626 94 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 15794574 Pathogen - hypothetical protein NMA1681 1 None None None 15795025 Common pgi2 glucose-6-phosphate isomerase 2 NMA2154 200 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 15794172 Common - hypothetical protein NMA1230 38 COG3926 zliS, Putative secretion activating protein General function prediction only 15794857 Common recC exodeoxyribonuclease V NMA1974 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 15793374 Pathogen - hypothetical protein NMA0366 1 None None None 15794676 Common - AraC-family transcriptional regulator NMA1783 128 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15794726 Pathogen - hypothetical protein NMA1836 1 None None None 15794526 Common fis factor-for-inversion-stimulation protein NMA1632 95 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 15793170 Common rpoB DNA-directed RNA polymerase subunit beta NMA0142 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 15793726 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B NMA0751 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 15794000 Common - hypothetical protein NMA1049 60 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 15794227 Pathogen - hypothetical protein NMA1298 1 None None None 15793204 Common - IS1016 transposase NMA0176 4 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793980 Common purA adenylosuccinate synthetase NMA1024 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 15794710 Common gpxA glutathione peroxidase NMA1820 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 15794662 Common - hypothetical protein NMA1769 4 COG3680 COG3680, Uncharacterized protein conserved in bacteria Function unknown 15793312 Common - symport protein NMA0298 151 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 15793216 Common rfbA2 glucose-1-phosphate thymidylyltransferase NMA0188 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15794757 Pathogen - hypothetical protein NMA1869 1 None None None 15793587 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit NMA0597 201 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 15794877 Pathogen - hypothetical protein NMA1997 1 None None None 15794736 Common - hypothetical protein NMA1848 21 COG4388 COG4388, Mu-like prophage I protein General function prediction only 15793365 Common - transferase NMA0356 132 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 15793613 Common lspA lipoprotein signal peptidase NMA0623 194 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15794615 Common - peptidyl-prolyl isomerase NMA1722 126 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 15794819 Common - cytochrome NMA1936 44 COG3245 CycB, Cytochrome c5 Energy production and conversion 15794335 Pathogen - hypothetical protein NMA1424 1 None None None 15794249 Common - hypothetical protein NMA1322 9 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 15794225 Pathogen - hypothetical protein NMA1296 1 None None None 15793500 Common - hypothetical protein NMA0501 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 15793878 Common holA DNA polymerase III subunit delta NMA0913 78 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 15795067 Common phr deoxyribodopyrimidine photolyase NMA2198 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 15793472 Common - IS1016 transposase NMA0471 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793507 Common - chromosome segregation proteins NMA0508 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 15794139 Pathogen - hypothetical protein NMA1195 1 None None None 15793268 Common gltX glutamyl-tRNA synthetase NMA0250 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15794132 Common - amidase NMA1188 5 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15794957 Common - hypothetical protein NMA2081 18 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 15794967 Common nadB L-aspartate oxidase NMA2092 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 15794940 Common murG UDP-N-acetylglucosamine--N-acetylmuramyl-(pentape pyrophosphoryl-undecaprenol N-acetylglucosamine transferase NMA2062 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15793857 Common rnc ribonuclease III NMA0888 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 15794760 Pathogen - hypothetical protein NMA1872 1 None None None 15794782 Common infB translation initiation factor IF-2 NMA1897 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 15794898 Common - hypothetical periplasmic protein NMA2018 2 None None None 15793264 Common - glyceraldehyde 3-phosphate dehydrogenase C NMA0246 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15793297 Common - integral membrane protein NMA0280 96 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 15794276 Pathogen - periplasmic protein NMA1355 1 None None None 15794452 Common - inositol monophosphate family protein NMA1559 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 15793607 Common fhs formate--tetrahydrofolate ligase NMA0617 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 15794796 Common - periplasmic protein NMA1911 20 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 15794449 Common lpdA dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) NMA1556 239 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15794925 Common - hypothetical protein NMA2047 5 None None None 15793430 Common - hypothetical protein NMA0425 16 None None None 15794808 Common - protease NMA1923 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15794902 Common rpsT 30S ribosomal protein S20 NMA2022 206 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 161353789 Common nusA transcription elongation factor NusA NMA1896 218 COG0195 NusA, Transcription elongation factor Transcription 15793917 Common - hypothetical protein NMA0960 29 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15794436 Common - IS1016 transposase NMA1543 8 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793377 Common hemK HemK protein NMA0369 226 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15794682 Common - hypothetical protein NMA1791 42 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 15793210 Common - lipoprotein NMA0182 2 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 15794271 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha NMA1349 197 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 15794248 Common - hypothetical protein NMA1321 22 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 15794195 Common folB dihydroneopterin aldolase NMA1262 87 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 15794140 Pathogen - hypothetical protein NMA1196 1 None None None 15793501 Common rpsU 30S ribosomal protein S21 NMA0502 97 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 15794232 Common - amidase NMA1303 5 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15793316 Common argG argininosuccinate synthase NMA0303 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 15793875 Common - transmembrane transport protein NMA0909 76 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 15793087 Common gyrB DNA gyrase subunit B NMA0056 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15794278 Pathogen - hypothetical protein NMA1357 1 None None None 15793711 Pathogen - hypothetical protein NMA0735 1 None None None 15793605 Common - sugar-phosphate nucleotidyl transferase NMA0615 217 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 15793094 Common - lipoprotein NMA0065 54 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 15794839 Common - IS1016 transposase NMA1956 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794184 Common abcZ ABC transporter ATP-binding protein NMA1249 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15794893 Common bioF 8-amino-7-oxononanoate synthase NMA2013 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 15794716 Common - hypothetical protein NMA1826 23 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 15793437 Common - hypothetical protein NMA0432 12 None None None 15794962 Common - transcriptional regulator NMA2087 3 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 15793059 Common - hypothetical protein NMA0025 10 None None None 15793474 Common groEL chaperonin GroEL NMA0473 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15793180 Common - hypothetical protein NMA0153 5 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 161353790 Common hisB imidazoleglycerol-phosphate dehydratase NMA1772 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 15794434 Common - hypothetical protein NMA1541 94 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15794442 Common - lipoprotein NMA1549 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 15793164 Common rpsG 30S ribosomal protein S7 NMA0136 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 15793175 Common nusG transcription antitermination protein NusG NMA0147 215 COG0250 NusG, Transcription antiterminator Transcription 15794174 Pathogen - hypothetical protein NMA1232 1 None None None 15793489 Common - periplasmic/outer membrane protein NMA0490 93 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 15795020 Common - inner membrane hypothetical protein NMA2149 2 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 15794746 Pathogen - hypothetical protein NMA1858 1 None None None 15793299 Common - hypothetical protein NMA0282 47 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 15794932 Common prpC methylcitrate synthase NMA2054 194 COG0372 GltA, Citrate synthase Energy production and conversion 15794780 Common - hypothetical protein NMA1895 158 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 15793884 Common - cytochrome C NMA0925 43 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 15794724 Pathogen - hypothetical protein NMA1834 1 None None None 15794587 Common - hypothetical protein NMA1694 216 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15793805 Pathogen - peptide chain release factor 3 remnant NMA0835 1 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 15793615 Common - phosphatase NMA0625 70 COG0546 Gph, Predicted phosphatases General function prediction only 15793582 Pathogen - hypothetical protein NMA0591 1 None None None 15793566 Common - ferric siderophore receptor protein NMA0575 96 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 15793914 Pathogen - hypothetical protein NMA0957 1 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 15794751 Pathogen - hypothetical protein NMA1863 1 None None None 15794598 Common - hypothetical protein NMA1705 140 COG1354 COG1354, Uncharacterized conserved protein Function unknown 15794485 Common lldA L-lactate dehydrogenase NMA1592 113 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 15794318 Common recR recombination protein NMA1406 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15795096 Common - hypothetical inner membrane protei NMA2227 15 None None None 15794660 Common - lipoprotein NMA1767 115 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 15794396 Common - hypothetical protein NMA1496 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 15794703 Common trkA potassium transporter peripheral membrane component NMA1813 139 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15794821 Common trmA tRNA (uracil-5-)-methyltransferase NMA1938 152 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 15794858 Common - integral membrane protein NMA1975 67 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 15793070 Pathogen - hypothetical protein NMA0038 1 None None None 15793725 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C NMA0750 47 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 15793900 Common bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase NMA0942 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 15794685 Pathogen - hypothetical protein NMA1794 1 None None None 15793138 Common rplO 50S ribosomal protein L15 NMA0110 195 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 15793529 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein NMA0534 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 15793597 Common - hypothetical protein NMA0607 17 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 15793732 Pathogen - hypothetical protein NMA0757 1 None None None 15794948 Common penA penicillin-binding protein 2 NMA2072 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15793985 Pathogen - hypothetical protein NMA1029 1 None None None 15794568 Common - transglycosylase NMA1674 64 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15794998 Common - integral membrane signal transducer protein NMA2127 109 None None None 15794733 Common - hypothetical protein NMA1844 21 COG4387 COG4387, Mu-like prophage protein gp36 Function unknown 15794386 Common - IS1655 transposase NMA1486 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 15794263 Common - poly-isoprenyl transferase NMA1339 113 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 15794087 Common - redoxin NMA1141 106 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15793229 Common rfbB dTDP-glucose 4,6-dehydratase NMA0204 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 15794974 Common galM aldose 1-epimerase (mutarotase) NMA2099 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 15793353 Common cybB cytochrome B561 NMA0343 24 COG3038 CybB, Cytochrome B561 Energy production and conversion 15793556 Common - DNA-binding protein NMA0564 34 COG2944 COG2944, Predicted transcriptional regulator Transcription 15793818 Common galU UTP--glucose-1-phosphate uridylyltransferase NMA0848 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15794577 Common - aminotransferase AlaT NMA1684 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15794047 Pathogen - hypothetical protein NMA1099 1 None None None 15793813 Common fbpB iron-uptake permease inner membrane protein NMA0843 201 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 15793714 Common - transcriptional regulator NMA0738 51 COG2932 COG2932, Predicted transcriptional regulator Transcription 15793790 Common - polyamine permease inner membrane protein NMA0817 205 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 15794134 Pathogen - hypothetical protein NMA1190 2 None None None 15794657 Common - hypothetical protein NMA1764 58 COG1359 COG1359, Uncharacterized conserved protein Function unknown 15793779 Common - sec-independent protein translocase component NMA0805 29 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 15794285 Common cysN sulphate adenylate transferase subunit 1 NMA1364 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 15794478 Common clpX ATP-dependent protease ATP-binding subunit NMA1585 243 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 15793606 Common - integral membrane protein NMA0616 44 COG2510 COG2510, Predicted membrane protein Function unknown 15794822 Common aroC chorismate synthase NMA1939 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 15794926 Common - hypothetical protein NMA2048 145 COG1959 COG1959, Predicted transcriptional regulator Transcription 15793788 Common rpsO 30S ribosomal protein S15 NMA0815 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 15793118 Common - hypothetical protein NMA0089 8 None None None 15794979 Common rmpM outer membrane protein class 4 NMA2105 138 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15793622 Pathogen - hypothetical protein NMA0634 1 None None None 15795050 Common folA dihydrofolate reductase NMA2179 144 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 15793391 Common petA ubiquinol-cytochrome c reductase iron-sulfur subunit NMA0383 92 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 15793035 Common - hypothetical protein NMA0001 20 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 15793339 Common tsf elongation factor Ts NMA0327 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 15793278 Common - integral membrane protein NMA0260 7 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 15793452 Common - hypothetical protein NMA0449 16 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 15793639 Common pilM pilus assembly protein NMA0654 61 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 15793459 Common - hypothetical protein NMA0456 4 COG5346 COG5346, Predicted membrane protein Function unknown 15794006 Common - glycosyl transferase NMA1057 214 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15793493 Common - acetyltransferase NMA0494 48 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15793820 Pathogen - hypothetical protein NMA0850 1 None None None 15794080 Pathogen - lipoprotein NMA1134 1 None None None 15794762 Common - hypothetical protein NMA1874 5 None None None 15795049 Common - hypothetical protein NMA2178 47 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 15793340 Common rpsB 30S ribosomal protein S2 NMA0328 220 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 15794512 Common - insertion element IS1106 transposase NMA1618 35 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15793144 Common rpsN 30S ribosomal protein S14 NMA0116 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 15793304 Common tbpA thiamin-binding periplasmic protein NMA0287 75 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 15793575 Common - acetyltransferase NMA0584 146 COG0456 RimI, Acetyltransferases General function prediction only 15793263 Common - hypothetical protein NMA0245 93 COG1720 COG1720, Uncharacterized conserved protein Function unknown 15794519 Common - RTX family exoprotein NMA1625 19 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 15793998 Common cspA transcriptional regulator NMA1047 180 COG1278 CspC, Cold shock proteins Transcription 15794804 Common gmk guanylate kinase NMA1919 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 15793187 Common - two-component sensor NMA0160 219 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 15793539 Common - hypothetical protein NMA0545 36 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 15793860 Common greB transcription elongation factor GreB NMA0891 180 COG0782 GreA, Transcription elongation factor Transcription 15793364 Common folD methylenetetrahydrofolate dehydrogenase/cyclohydrolase NMA0354 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 15794474 Pathogen - membrane lipoprotein NMA1581 1 None None None 15793498 Common regG ClpXP protease specificity-enhancing factor NMA0499 64 COG2969 SspB, Stringent starvation protein B General function prediction only 15794621 Common - methylated-DNA-protein-cysteine methyltransferase NMA1728 199 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 15794616 Pathogen - proline-rich repeat protein NMA1723 1 None None None 15795033 Common rplU 50S ribosomal protein L21 NMA2162 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 15793129 Common minC septum formation inhibitor NMA0101 92 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 15794251 Common - hypothetical protein NMA1324 16 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 15794022 Pathogen - membrane protein NMA1074 1 None None None 15793755 Pathogen - hypothetical protein NMA0780 1 None None None 15793223 Common ctrA capsule polysaccharide export outer membrane protein NMA0198 64 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 15794408 Common cmk cytidylate kinase NMA1514 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 15794711 Common - hypothetical protein NMA1821 5 None None None 15793044 Common nuoG NADH dehydrogenase subunit G NMA0010 192 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 15793547 Common dnaN DNA polymerase III subunit beta NMA0553 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 15793411 Common nlaB 1-acyl-SN-glycerol-3-phosphate acyltransferase NMA0404 182 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15793470 Common lysA diaminopimelate decarboxylase NMA0468 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 15794912 Common - MutT-related protein NMA2032 143 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15793845 Pathogen - hypothetical protein NMA0876 1 None None None 15793929 Common dapF diaminopimelate epimerase NMA0972 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 15794125 Common - integral membrane protein NMA1180 29 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 15793616 Common - hypothetical protein NMA0629 19 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 15794031 Pathogen - periplasmic protein NMA1083 1 None None None 15794955 Common - hypothetical protein NMA2079 2 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 15794984 Common anmK anhydro-N-acetylmuramic acid kinase NMA2111 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 15794928 Common ackA2 acetate kinase NMA2050 162 COG0282 ackA, Acetate kinase Energy production and conversion 15794447 Common aceE pyruvate dehydrogenase subunit E1 NMA1554 140 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 15794415 Common ndk nucleoside diphosphate kinase NMA1521 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 15794464 Common - iron/sulphur-binding oxidoreductase NMA1571 145 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 15794506 Common - zinc-binding alcohol dehydrogenase NMA1612 194 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15794439 Common - carboxy-terminal processing protease NMA1546 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 15793752 Pathogen - hypothetical protein NMA0777 1 None None None 15793080 Common - RNA polymerase sigma factor NMA0049 105 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 15793558 Pathogen - hypothetical protein NMA0567 1 None None None 15793974 Pathogen - hypothetical protein NMA1018 1 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 15794989 Pathogen - hypothetical protein NMA2116 1 None None None 15794060 Common - hypothetical protein NMA1113 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15793075 Common acpP acyl carrier protein NMA0043 207 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15794563 Common tkt transketolase NMA1669 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15794157 Common - hypothetical protein NMA1215 4 COG1598 COG1598, Uncharacterized conserved protein Function unknown 15793064 Common - transmembrane transport protein NMA0031 24 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 15793947 Common - hypothetical protein NMA0990 25 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 15794889 Common - hypothetical protein NMA2009 2 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 15793678 Pathogen - hypothetical protein NMA0697 1 None None None 15793346 Common - hypothetical protein NMA0336 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 15793337 Pathogen mafA adhesin NMA0325 1 None None None 15793271 Common - periplasmic thiredoxin NMA0253 80 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 15793484 Common - ABC transport ATP-binding protein NMA0485 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 15793123 Common valS valyl-tRNA synthetase NMA0094 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793637 Common pilO pilus assembly protein NMA0652 45 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 15793908 Common - hypothetical protein NMA0951 138 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 15793979 Common hisZ ATP phosphoribosyltransferase regulatory subunit NMA1023 104 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 15795005 Common - hypothetical protein NMA2134 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 15793671 Pathogen - hypothetical protein NMA0691 1 None None None 15794557 Common - hypothetical protein NMA1663 87 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 15793401 Common - ABC-transport system ATP-binding protein NMA0393 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15794960 Common - transposase fragment NMA2085 52 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794092 Common sdhB succinate dehydrogenase iron-sulfur subunit NMA1146 199 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 15793089 Common - transmembrane transport protein NMA0060 216 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15794424 Pathogen - hypothetical protein NMA1531 1 None None None 15794903 Common - polyamine permease substrate-binding protein NMA2023 125 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15793314 Pathogen - integral membrane protein NMA0300 1 None None None 15793371 Common thiE thiamin-phosphate pyrophosphorylase NMA0363 199 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 15793510 Pathogen atpI ATP synthase I NMA0512 1 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 15794057 Common - pilin NMA1110 60 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 15793835 Common - hypothetical protein NMA0866 12 None None None 15793822 Common ntpA dATP pyrophosphohydrolase NMA0852 53 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15794919 Common pheA chorismate mutase NMA2039 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 15794539 Common - lipoprotein NMA1645 143 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15793796 Common rho transcription termination factor Rho NMA0825 204 COG1158 Rho, Transcription termination factor Transcription 15793580 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase NMA0589 228 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 15794364 Common - hypothetical protein NMA1462 112 COG2606 EbsC, Uncharacterized conserved protein Function unknown 15795079 Common - inner membrane virulence factor protein NMA2210 196 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 15794741 Pathogen - hypothetical protein NMA1853 1 None None None 15794374 Common - hypothetical protein NMA1473 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 15795069 Common dinG ATP-dependent DNA helicase DinG NMA2200 132 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 15794015 Common - periplasmic protein NMA1066 41 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15793881 Common - hypothetical protein NMA0916 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 15794695 Common - two component response regulator NMA1805 211 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15794090 Common sdhD succinate dehydrogenase hydrophobic membrane anchor protein NMA1144 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 15794531 Common - hypothetical protein NMA1637 18 None None None 15794204 Common lgt prolipoprotein diacylglyceryl transferase NMA1273 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 15793560 Pathogen secG preprotein translocase subunit SecG NMA0569 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 15793230 Common rfbA glucose-1-phosphate thymidylyltransferase NMA0205 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15793924 Common rfbD dTDP-4-dehydrorhamnose reductase NMA0967 170 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 15794450 Common - hypothetical protein NMA1557 8 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 15794398 Common nrdB ribonucleotide-diphosphate reductase subunit beta NMA1498 151 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 15793381 Common thiF ThiF protein NMA0373 217 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 15793517 Common atpD F0F1 ATP synthase subunit beta NMA0519 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 15793648 Common - IS1016 transposase NMA0664 4 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793684 Common - membrane protein NMA0706 29 COG3759 COG3759, Predicted membrane protein Function unknown 15794647 Common - hypothetical protein NMA1754 6 None None None 15794600 Common argS arginyl-tRNA synthetase NMA1707 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15794648 Common purN phosphoribosylglycinamide transformylase NMA1755 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 15794338 Common ribB bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein NMA1429 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 15793432 Common - modification methylase (cytosine-specific DNA methylase) NMA0427 108 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15793132 Common rpsD 30S ribosomal protein S4 NMA0104 216 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15793590 Common - hypothetical protein NMA0600 47 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15793669 Pathogen - hypothetical protein NMA0689 1 None None None 15793761 Pathogen - hypothetical protein NMA0786 1 None None None 15793987 Common htpX heat shock protein HtpX NMA1031 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15794040 Common - hypothetical protein NMA1092 190 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 15793774 Common - hypothetical protein NMA0800 11 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 15793186 Common - two-component trancriptional regulator NMA0159 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15793240 Common - hypothetical protein NMA0217 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 15794033 Common - hypothetical protein NMA1085 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15794357 Common leuD isopropylmalate isomerase small subunit NMA1452 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 15794698 Common metZ O-succinylhomoserine sulfhydrolase NMA1808 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15794212 Pathogen - hypothetical protein NMA1283 2 None None None 15794176 Common - transposase NMA1234 108 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15795044 Common - hypothetical protein NMA2173 16 COG4255 COG4255, Uncharacterized protein conserved in bacteria Function unknown 15794545 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit NMA1651 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 15793418 Common gntP gluconate permease NMA0413 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 15793641 Common - GTPase EngB NMA0656 184 COG0218 COG0218, Predicted GTPase General function prediction only 15794166 Pathogen - hypothetical protein NMA1224 1 None None None 15795027 Common pilD type IV prepilin leader peptidase NMA2156 143 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15793942 Common upp uracil phosphoribosyltransferase NMA0985 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 15795074 Common - hypothetical protein NMA2205a 118 COG0557 VacB, Exoribonuclease R Transcription 15793692 Common - transmembrane transport protein NMA0715 57 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 15794638 Common - hypothetical protein NMA1745 77 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 15794844 Common - integral membrane ion transporter NMA1961 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 15793704 Common - periplasmic protein NMA0728 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 161353794 Common hslO Hsp33-like chaperonin NMA0441 115 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 15794072 Common - transmembrane transport protein NMA1126 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15793892 Common pheS phenylalanyl-tRNA synthetase subunit alpha NMA0933 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 15794483 Common - type III restriction/modification system modification methylase NMA1590 108 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 15793766 Common rplS 50S ribosomal protein L19 NMA0792 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 15794771 Common - Ner-like DNA-binding protein NMA1883 24 COG3423 Nlp, Predicted transcriptional regulator Transcription 15794674 Pathogen - hypothetical protein NMA1781 1 None None None 15794554 Common rep ATP-dependent DNA helicase NMA1660 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15795059 Common - hypothetical protein NMA2189 109 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 15794459 Common - hypothetical protein NMA1566 131 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 15793195 Common pyrB aspartate carbamoyltransferase catalytic subunit NMA0168 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 15794293 Common guaB inositol-5-monophosphate dehydrogenase NMA1372 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15794350 Common - hypothetical protein NMA1445 211 COG2262 HflX, GTPases General function prediction only 15793329 Pathogen - hypothetical protein NMA0317 1 None None None 15794356 Pathogen - lipoprotein NMA1451 1 None None None 15793116 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NMA0087 151 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 15793584 Common orn oligoribonuclease NMA0594 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 15794867 Common tonB TonB protein NMA1985 21 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 15794147 Common - hypothetical protein NMA1203 64 COG2128 COG2128, Uncharacterized conserved protein Function unknown 15793748 Pathogen - hypothetical protein NMA0773 1 None None None 15794082 Common metX homoserine O-acetyltransferase NMA1136 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 15794764 Pathogen - hypothetical protein NMA1876 1 None None None 15793072 Pathogen - hypothetical protein NMA0040 1 None None None 15794753 Pathogen - hypothetical protein NMA1865 1 None None None 15793723 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E NMA0748 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 15793272 Common ftsE ABC transporter ATP-binding protein NMA0254 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 15793189 Common - SUN homolog NMA0162 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 15794802 Common spoT guanosine-3',5'-bis(diphosphate) 3'-pyrophophohydrolase NMA1917a 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 15793799 Common - phosphatase NMA0828 144 COG0546 Gph, Predicted phosphatases General function prediction only 15794623 Common dapE succinyl-diaminopimelate desuccinylase NMA1730 213 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15794610 Pathogen - hypothetical protein NMA1717 1 None None None 15793438 Common hrpA' ATP-dependent DNA helicase NMA0433 132 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 15793651 Common - oxidoreductase NMA0666 98 COG0431 COG0431, Predicted flavoprotein General function prediction only 15793859 Common trpF N-(5'-phosphoribosyl)anthranilate isomerase NMA0890 192 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 15794799 Pathogen - hypothetical protein NMA1914 1 None None None 15793235 Common - DNA transport competence protein NMA0211 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 15793825 Common - hypothetical protein NMA0855 4 None None None 15794149 Common dld D-lactate dehydrogenase NMA1205 69 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15793716 Pathogen - hypothetical protein NMA0740 1 None None None 15794529 Common - hypothetical protein NMA1635 101 COG3177 COG3177, Uncharacterized conserved protein Function unknown 15794701 Common hisJ histidine-binding periplasmic protein NMA1811 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15794581 Common - phosphoglycolate phosphatase NMA1688 176 COG0546 Gph, Predicted phosphatases General function prediction only 15794722 Pathogen - hypothetical protein NMA1832 1 None None None 15794571 Common - hypothetical protein NMA1678 9 None None None 15794197 Common - integral membrane protein NMA1264 26 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 15793521 Common glyS glycyl-tRNA synthetase subunit beta NMA0523 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 15794596 Common - hypothetical protein NMA1703 152 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15794471 Common trxA thioredoxin I NMA1578 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15793713 Pathogen - hypothetical protein NMA0737 1 None None None 15794076 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase NMA1130 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 15794522 Common - hypothetical protein NMA1628 30 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 15793603 Common - marR-family transcriptional regulator NMA0613 36 COG1846 MarR, Transcriptional regulators Transcription 15793873 Common comL competence lipoprotein NMA0907 125 COG4105 ComL, DNA uptake lipoprotein General function prediction only 15794331 Common - two-component system response regulator NMA1419 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15793211 Common gltS sodium/glutamate symport carrier protein NMA0183 51 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 15793503 Common - ABC transport ATP-binding subunit NMA0504 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 15794990 Pathogen - hypothetical protein NMA2117 1 None None None 15794964 Common - cytoplasmic membrane protein NMA2089 64 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 15794229 Pathogen - membrane protein NMA1300 1 None None None 15794273 Common - RNA methyltransferase NMA1351 192 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15794905 Pathogen tbpB transferrin-binding protein B NMA2025 3 None None None 15795063 Common - TonB-dependent receptor protein NMA2193 111 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 15794234 Pathogen - hypothetical protein NMA1305 2 None None None 15794461 Common gatA Glu-tRNA(Gln) amidotransferase subunit A NMA1568 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 15793351 Common - hypothetical protein NMA0341 150 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 15794895 Common - integral membrane transport protein NMA2015 88 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15793370 Common - hypothetical protein NMA0362 17 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 15794207 Pathogen - membrane protein NMA1276 1 None None None 15793276 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase NMA0258 224 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 15794792 Common - IS1016 transposase NMA1907A 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794748 Pathogen - hypothetical protein NMA1860 1 None None None 15793057 Common - hypothetical protein NMA0023 4 None None None 15794432 Common - cation-transporting ATPase NMA1539 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15794062 Common - IS1106A3 transposase NMA1115 38 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15793096 Pathogen - hypothetical protein NMA0067 1 None None None 15795022 Common ilvE branched-chain amino acid aminotransferase NMA2151 210 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15794241 Common - DNA-binding protein NMA1312 7 None None None 15794817 Common gcvP glycine dehydrogenase NMA1934 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 15793302 Pathogen - lipoprotein NMA0285a 1 None None None 15794714 Common - hypothetical protein NMA1824 10 None None None 15794828 Common prfA peptide chain release factor 1 NMA1945 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 15794953 Common - integral membrane antobiotic resistance protein NMA2077 201 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 15793850 Common cnp1 periplasmic protein NMA0881 3 None None None 15793182 Pathogen - hypothetical protein NMA0155 1 None None None 15794708 Common - hypothetical protein NMA1818 73 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15793127 Common minE cell division topological specificity factor NMA0099 82 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 15793042 Common nuoI NADH dehydrogenase subunit I NMA0008 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15793344 Common mqo malate:quinone oxidoreductase NMA0333 57 COG0579 COG0579, Predicted dehydrogenase General function prediction only 15795047 Pathogen - hypothetical protein NMA2176 1 None None None 15793577 Pathogen - lipoprotein NMA0586 2 None None None 15793225 Common sacB capsule biosynthesis protein NMA0200 20 None None None 15793545 Pathogen rpmH 50S ribosomal protein L34 NMA0551 2 None None None 15794783 Common - integral membrane protein NMA1898 17 COG1161 COG1161, Predicted GTPases General function prediction only 15794687 Pathogen - hypothetical protein NMA1796 1 None None None 15793937 Common holB DNA polymerase III subunit delta' NMA0980 217 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 15795042 Common - hypothetical protein NMA2171 89 COG1738 COG1738, Uncharacterized conserved protein Function unknown 15793366 Common birA bifunctional biotin--[acetyl-CoA-carboxylase] ligase/pantothenate kinase NMA0357 215 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 15794334 Pathogen - hypothetical protein NMA1423 1 None None None 15793916 Common - regulator NMA0959 29 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 15793537 Common - hypothetical protein NMA0543 41 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 15794833 Common dhpS dihydropteroate synthase NMA1950 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 15793757 Common - phage replication protein NMA0782 12 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 15794343 Common - integral membrane protein NMA1438 9 None None None 15794890 Pathogen - hypothetical protein NMA2010 1 None None None 15793862 Common - membrane protein NMA0894 26 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 15793208 Pathogen - hypothetical protein NMA0180 1 None None None 15793554 Common - hypothetical protein NMA0562 122 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15793155 Common rplW 50S ribosomal protein L23 NMA0127 119 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 15793201 Common - hypothetical protein NMA0173 41 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15794673 Pathogen - hypothetical protein NMA1780 1 None None None 15793930 Pathogen - integral membrane protein NMA0973 1 None None None 15793494 Common rpmE 50S ribosomal protein L31 NMA0495 204 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15793730 Common - hypothetical protein NMA0755 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 15794986 Common mafB2 adhesin MafB2 NMA2113 3 None None None 15794731 Common - hypothetical protein NMA1842 4 None None None 15793911 Common - hypothetical protein NMA0954 67 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15794038 Common - periplasmic protein NMA1090 105 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15794049 Pathogen - hypothetical protein NMA1101 1 None None None 15794579 Common - hypothetical protein NMA1686 17 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 15793811 Common - phosphate acyltransferase NMA0841 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 15794946 Common murF UDP-MurNAc-pentapeptide synthetase NMA2068 204 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 15795088 Common - periplasmic protein NMA2219 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 15794182 Common trpE anthranilate synthase component I NMA1247 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15794476 Pathogen - hypothetical protein NMA1583 1 None None None 15794513 Common - insertion element IS1106 transposase NMA1619 21 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15794643 Common - hypothetical protein NMA1750 48 COG2431 COG2431, Predicted membrane protein Function unknown 15794934 Common - hypothetical protein NMA2056 136 COG2252 COG2252, Permeases General function prediction only 15794089 Common sdhC succinate dehydrogenase cytochrome B subunit NMA1143 74 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 15794655 Common argF ornithine transcarbamoylase NMA1762 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 15794977 Common pgpA phosphatidylglycerophosphatase A NMA2102 102 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 15794561 Common - inner membrane protein NMA1667 22 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 15794972 Common pgm1 beta-phosphoglucomutase NMA2097 133 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15794542 Common - hypothetical protein NMA1648 152 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 15794109 Common trpG anthranilate synthase component II NMA1163 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 15793983 Pathogen - DNA-binding protein NMA1027 1 None None None 15793624 Common avtA valine--pyruvate transaminase NMA0636 184 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 15793869 Common - hypothetical protein NMA0903 10 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 15794872 Common grxB glutaredoxin 2 NMA1990 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 15794405 Common - hypothetical protein NMA1506 35 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15794472 Common - hypothetical protein NMA1579 140 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 15793037 Pathogen - hypothetical protein NMA0003 1 None None None 15794008 Common - periplasmic protein NMA1059 21 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 15795009 Common - glutamyl-Q tRNA(Asp) synthetase NMA2138 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15795098 Common nuoM NADH dehydrogenase subunit M NMA2229 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 15793468 Common cyaY frataxin-like protein NMA0466 43 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 15794136 Pathogen - hypothetical protein NMA1192 1 None None None 15793375 Common tldD TLDD protein homolog NMA0367 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15793572 Pathogen - hypothetical protein NMA0581 1 None None None 15794420 Common tig trigger factor NMA1526 217 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 15793104 Common rnhB ribonuclease HII NMA0075 238 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 15794100 Common sucD succinyl-CoA synthetase subunit alpha NMA1154 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 15794883 Pathogen - hypothetical protein NMA2003 1 None None None 15793153 Common rpsS 30S ribosomal protein S19 NMA0125 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 15793322 Pathogen - hypothetical protein NMA0310 1 None None None 15793227 Common sacD capsule biosynthesis protein NMA0202 4 COG4092 COG4092, Predicted glycosyltransferase involved in capsule biosynthesis Cell envelope biogenesis, outer membrane 15793369 Common thiG thiazole synthase NMA0361 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 15794509 Pathogen - hypothetical protein NMA1615 1 None None None 15795003 Common - outer membrane hypothetical protein NMA2132 69 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 15794368 Common - type III restriction-modification system endonuclease protein NMA1466 39 COG3587 COG3587, Restriction endonuclease Defense mechanisms 15793782 Common - zinc-binding alcohol dehydrogenase NMA0808 172 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15793676 Common - hypothetical protein NMA0696 4 None None None 15793794 Pathogen - hypothetical protein NMA0821 1 None None None 15794537 Common greA transcription elongation factor NMA1643 197 COG0782 GreA, Transcription elongation factor Transcription 15794515 Common - IS1016 transposase NMA1621 5 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794094 Common gltA type II citrate synthase NMA1148 194 COG0372 GltA, Citrate synthase Energy production and conversion 15794944 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase NMA2066 215 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15794112 Common - hypothetical protein NMA1167 11 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 15793403 Pathogen - hypothetical protein NMA0395 1 None None None 15794308 Common hom homoserine dehydrogenase NMA1395 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 15794666 Common - hypothetical protein NMA1773 174 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 15794559 Common - DNA polymerase III subunit NMA1665 187 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15794743 Pathogen - hypothetical protein NMA1855 1 None None None 15794921 Common - hypothetical protein NMA2041 54 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 15793968 Common - carbon-sulphur lyase NMA1012 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15794055 Pathogen - membrane protein NMA1108 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 15794498 Pathogen - hypothetical protein NMA1603 1 None None None 15793586 Common accC acetyl-CoA carboxylase biotin carboxylase component NMA0596 235 COG0439 AccC, Biotin carboxylase Lipid metabolism 15794366 Common - hypothetical protein NMA1464 124 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 15794036 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase NMA1088 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 15793642 Common cyc cytochrome C NMA0658 55 COG2863 COG2863, Cytochrome c553 Energy production and conversion 15794852 Common mtrD drug efflux protein NMA1969 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 15793161 Common rpsJ 30S ribosomal protein S10 NMA0133 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 15794376 Common - hypothetical protein NMA1475 35 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 15794417 Common - lipoprotein NMA1523 72 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15794403 Common plsC 1-acyl-SN-glycerol-3-phosphate acyltransferase NMA1504 117 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15794202 Common leuA 2-isopropylmalate synthase NMA1270 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15794123 Pathogen - hypothetical protein NMA1178 1 None None None 15794298 Common bfrA bacterioferritin A NMA1377 103 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 15793293 Common metG methionyl-tRNA synthetase NMA0275 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793066 Common - IS1655 transposase NMA0033 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 15794431 Common trxB thioredoxin reductase NMA1538 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15794462 Common - hypothetical protein NMA1569 20 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 15794406 Common - membrane bound murein transglycosylase NMA1507 134 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15794345 Common thrC threonine synthase NMA1440 158 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 15794422 Common uraA uracil permease NMA1528 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15794766 Pathogen - hypothetical protein NMA1878 1 None None None 15794155 Common - hypothetical protein NMA1211 2 None None None 15794491 Common hscB chaperone protein NMA1598 57 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 15793335 Pathogen - hypothetical protein NMA0323 1 None None None 15793949 Common radA DNA repair protein RadA NMA0992 206 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 15794198 Common - integral membrane protein NMA1265 14 COG3235 COG3235, Predicted membrane protein Function unknown 15793898 Pathogen fxsA FxsA NMA0940 2 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 15793135 Pathogen rpmJ 50S ribosomal protein L36 NMA0107 1 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 15793428 Common - DNA transport competence protein NMA0423 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 15793842 Common - periplasmic protein NMA0873 4 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 15793486 Common - outer membrane transport protein NMA0487 98 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 15793655 Common - hypothetical protein NMA0672 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 15794188 Common glyA serine hydroxymethyltransferase NMA1254 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 15793944 Pathogen - secreted protein NMA0987 2 None None None 15794161 Pathogen - hypothetical protein NMA1219 1 None None None 15795029 Common - hypothetical protein NMA2158 63 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 15795052 Pathogen - hypothetical protein NMA2181 1 None None None 15793114 Common omp85 outer membrane protein OMP85 NMA0085 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 15794181 Common - hypothetical protein NMA1246 4 COG4333 COG4333, Uncharacterized protein conserved in bacteria Function unknown 15794162 Pathogen - hypothetical protein NMA1220 1 None None None 15795081 Common trpC indole-3-glycerol phosphate synthase NMA2212 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 15793667 Common - periplasmic protein NMA0687 44 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 15795017 Common tspA Neisseria-specific antigen protein, TspA NMA2146 27 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 15793525 Common - hypothetical protein NMA0528 202 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 15793213 Common lipB capsule polysaccharide modification protein NMA0185 31 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 15794043 Common - D-alanyl-D-alanine carboxypeptidase NMA1095 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15793702 Common adhA alcohol dehydrogenase NMA0725 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 15793864 Common folC bifunctional folylpolyglutamate synthase/dihydrofolate synthase NMA0896 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 15793085 Common prlC oligopeptidase A NMA0054 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 15793958 Common ppiB peptidyl-prolyl cis-trans isomerase B NMA1002 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 15793414 Common - amino-acid transport protein NMA0409 36 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15793802 Common - polyamine permease substrate-binding protein NMA0831 129 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15794869 Common - hypothetical protein NMA1987 12 None None None 15794168 Pathogen - hypothetical protein NMA1226 1 None None None 15793523 Common lgtB lacto-N-neotetraose biosynthesis glycosyl tranferase NMA0525 17 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 15793330 Pathogen - hypothetical protein NMA0318 1 None None None 15794773 Pathogen - hypothetical protein NMA1885 1 None None None 15794457 Pathogen - hypothetical protein NMA1564 2 None None None 15793591 Common - lysR-family transcriptional regulator NMA0601 189 COG0583 LysR, Transcriptional regulator Transcription 15794320 Common - hypothetical protein NMA1408 102 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 15793890 Common rpmI 50S ribosomal protein L35 NMA0931 193 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 15793686 Common - beta-hexosaminidase NMA0708 176 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 15793837 Common - periplasmic protein NMA0868 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 15794074 Common - membrane protein NMA1128 30 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 15794352 Common - hypothetical protein NMA1447 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 15794291 Common typA GTP-binding protein NMA1370 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 15794360 Common - periplasmic protein NMA1457 111 COG2353 COG2353, Uncharacterized conserved protein Function unknown 15794102 Pathogen - hypothetical protein NMA1156 1 None None None 15794878 Common - hypothetical protein NMA1998 2 None None None 15794191 Common - hypothetical protein NMA1258 21 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 15794315 Common - integral membrane protein NMA1403 216 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15793618 Common - hypothetical protein NMA0631 23 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 15793681 Common - hypothetical protein NMA0702 175 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 15793926 Common pnp polynucleotide phosphorylase/polyadenylase NMA0969 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 15793765 Common - ABC-transporter ATP-binding protein NMA0791 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 15793664 Pathogen - hypothetical protein NMA0681 1 None None None 15793902 Common - hypothetical protein NMA0944 6 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 15793776 Common - hypothetical protein NMA0802 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 15794119 Common - hypothetical protein NMA1174 45 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15794860 Common - hypothetical protein NMA1978 2 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 15793102 Common - amino-acid transport protein NMA0073 115 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 15793976 Common - tetR-family transcriptional regulator NMA1020 54 COG1309 AcrR, Transcriptional regulator Transcription 15794179 Common - hypothetical protein NMA1244 9 COG0456 RimI, Acetyltransferases General function prediction only 15793698 Common - hypothetical protein NMA0721 21 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 15794381 Common - IS1655 transposase NMA1481 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 15793996 Common clpA ATP-dependent protease ATP-binding protein NMA1045 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15794388 Common mltB murein hydrolase NMA1488 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 15793718 Common cysE serine acetyltransferase NMA0742 212 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 15794594 Common lysC aspartate kinase NMA1701 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15793611 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase NMA0621 211 COG0196 RibF, FAD synthase Coenzyme metabolism 15793256 Common purD phosphoribosylamine--glycine ligase NMA0238 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 15794391 Common mfd transcription-repair coupling factor NMA1491 228 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 15793249 Pathogen - periplasmic protein NMA0227 1 None None None 15793568 Common fetB2 ferric enterobactin transporter binding protein NMA0577 49 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 15793077 Common - transmembrane transport protein NMA0046 74 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 15793817 Common argH argininosuccinate lyase NMA0847 238 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 15794688 Pathogen tspB TspB protein NMA1797 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 15794214 Pathogen - hypothetical protein NMA1285 1 None None None 15793242 Common pilU pilT-like protein NMA0219 193 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 15794220 Common gam host-nuclease inhibitor protein NMA1291 7 COG4396 COG4396, Mu-like prophage host-nuclease inhibitor protein Gam General function prediction only 15794583 Pathogen - hypothetical protein NMA1690 1 None None None 15794327 Common - hypothetical protein NMA1415 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 15793413 Common - integral membrane protein NMA0408 26 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15794697 Common - hypothetical protein NMA1807 5 None None None 15793290 Pathogen pilS8 truncated pilin NMA0272 1 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 15793981 Pathogen - hypothetical protein NMA1025 1 None None None 15794021 Common - hypothetical protein NMA1073 2 None None None 15794929 Common - hypothetical protein NMA2051 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 15793815 Pathogen - hypothetical protein NMA0845 1 None None None 15793425 Common - integral membrane protein NMA0420 79 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 15794588 Common - fimbrial assembly protein NMA1695 9 None None None 15794548 Common - hypothetical protein NMA1654 13 None None None 15794853 Common mtrC membrane fusion protein NMA1970 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15793497 Common regF regulator of pilE expression NMA0498 109 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15794523 Pathogen - hypothetical DNA-binding protein NMA1629 1 None None None 15793456 Common fetA iron-regulated outer membrane protein NMA0453 42 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15794653 Common - hypothetical protein NMA1760 119 COG0795 COG0795, Predicted permeases General function prediction only 15794045 Common cysA sulphate permease ATP-binding protein NMA1097 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 15793258 Common - hypothetical protein NMA0240 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 15794103 Common - hypothetical protein NMA1157 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 15793737 Common - hypothetical protein NMA0762 48 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 15794282 Common ilvD dihydroxy-acid dehydratase NMA1361 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15794190 Pathogen - hypothetical protein NMA1257 1 None None None 15793167 Pathogen - periplasmic protein NMA0139 1 None None None 15793441 Common - hypothetical inner membrane protein NMA0436 83 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 15794237 Pathogen - hypothetical protein NMA1308 1 None None None 15793739 Pathogen - hypothetical protein NMA0764 1 None None None 15793514 Common atpH ATP synthase delta chain NMA0516 190 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 15793409 Common truA tRNA pseudouridine synthase A NMA0402 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 15794978 Common thiL thiamine monophosphate kinase NMA2103 195 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 15794306 Pathogen - periplasmic protein NMA1391 2 None None None 15794243 Common - hypothetical protein NMA1314 28 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 15793041 Pathogen - hypothetical protein NMA0007 1 None None None 15793398 Common - sugar transport PTS system IIA component NMA0390 87 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 15794138 Pathogen - hypothetical protein NMA1194 1 None None None 15793060 Common uvrD DNA helicase II NMA0027 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15793863 Pathogen tpc tetrapac protein NMA0895 1 None None None 15794922 Common - hypothetical protein NMA2044 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15794084 Common rpmE2 50S ribosomal protein L31 type B NMA1138 78 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15794321 Common - ABC-transporter ATP-binding protein NMA1409 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15793281 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NMA0263 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 15794987 Pathogen - hypothetical protein NMA2114 1 None None None 15794131 Common - hypothetical protein NMA1187 6 None None None 15793801 Common - periplasmic carrier protein NMA0830 74 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 15795099 Common - hypothetical protein NMA2230 69 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15794706 Common - tellurite resistance protein TehB NMA1816 23 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 15794037 Common panC pantoate--beta-alanine ligase NMA1089 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 15793574 Common - hypothetical protein NMA0583 34 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 15793368 Pathogen - hypothetical protein NMA0360 1 None None None 15794003 Common pcnB poly(A) polymerase NMA1053 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15793361 Pathogen - hypothetical protein NMA0350 1 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 15793358 Common cysS cysteinyl-tRNA synthetase NMA0347 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793994 Common - type I restriction-modification system protein NMA1038 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15794314 Common - ABC-transporter ATP-binding protein NMA1402 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15793309 Common - hypothetical protein NMA0292 36 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 15793706 Common - thiol:disulphide interchange protein NMA0730 71 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15794564 Common fumC fumarate hydratase NMA1670 210 COG0114 FumC, Fumarase Energy production and conversion 15795008 Pathogen - hypothetical protein NMA2137 1 None None None 15793989 Common pyrF orotidine 5'-phosphate decarboxylase NMA1033 161 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 15794936 Common ftsA cell division protein NMA2058 185 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15794617 Common - hypothetical protein NMA1724 204 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15794255 Common - hypothetical protein NMA1328 7 None None None 15793543 Common - hypothetical protein NMA0549 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 15794122 Common pntA NAD(P) transhydrogenase subunit alpha NMA1177 165 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 15794346 Common - hypothetical protein NMA1441 11 None None None 15793239 Pathogen - lipoprotein NMA0216 1 None None None 15794441 Pathogen - hypothetical protein NMA1548 1 None None None 15793053 Common nuoA NADH dehydrogenase I chain A NMA0019 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 15794881 Pathogen - hypothetical protein NMA2001 1 None None None 15794275 Pathogen - hypothetical protein NMA1354 1 None None None 15794871 Pathogen - hypothetical integral membrane protein NMA1989 1 None None None 15794737 Common - hypothetical protein NMA1849 17 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 15794795 Common - hypothetical protein NMA1909 37 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 15793055 Common - hypothetical protein NMA0021 17 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 15794991 Pathogen - hypothetical protein NMA2118 2 None None None 15793126 Common oxyR hydrogen peroxide-inducible genes activator NMA0098 190 COG0583 LysR, Transcriptional regulator Transcription 15793422 Common - hypothetical protein NMA0417 194 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 15794811 Common - hypothetical integral membrane protein NMA1928 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 15793373 Common - permease NMA0365 18 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 15794430 Common rpsF 30S ribosomal protein S6 NMA1537 171 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 15793506 Common - aromatic acid decarboxylase NMA0507 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 15795024 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase NMA2153 137 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 15793466 Common - hypothetical protein NMA0464 6 COG4316 COG4316, Uncharacterized protein conserved in bacteria Function unknown 15793267 Pathogen - periplasmic protein NMA0249 1 None None None 15793579 Common xerC integrase/recombinase NMA0588 229 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 15793879 Pathogen - membrane protein NMA0914 1 None None None 15794885 Pathogen - cell-surface protein NMA2005 1 None None None 15793179 Common - DNA methylase NMA0151 207 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 15794178 Common - sulphate-binding protein NMA1243 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 15794966 Common - integral membrane drug resistance protein NMA2091 144 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 15795036 Common rpmG 50S ribosomal protein L33 NMA2165 140 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 15793098 Common lpxB lipid-A-disaccharide synthase NMA0069 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 15795092 Common - ABC transporter NMA2223 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15794206 Common argB acetylglutamate kinase NMA1275 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 15794171 Common - membrane protein NMA1229 3 None None None 15794595 Common rph ribonuclease PH NMA1702 180 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 15794814 Common tag DNA-3-methyladenine glycosylase I NMA1931 131 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 15793217 Common rfbB2 dTDP-glucose 4,6-dehydratase NMA0189 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 15793039 Common nuoK NADH dehydrogenase subunit K NMA0005 158 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 15793827 Common - hypothetical protein NMA0857 2 None None None 15794290 Common - hypothetical protein NMA1369 216 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 15794756 Common hupB2 DNA-binding protein HU-beta NMA1868 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15793091 Common gapA glyceraldehyde-3-phosphate dehydrogenase NMA0062 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15793385 Common - hypothetical protein NMA0377 25 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 15793951 Common - periplasmic protein NMA0994 106 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15794788 Common - disulphide bond formation protein NMA1903 44 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 15793918 Common hfq regulator NMA0961 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 15794336 Common ribA GTP cyclohydrolase II NMA1425 189 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 15794689 Pathogen - integral membrane protein NMA1798 1 None None None 15794011 Common rdgC recombination associated protein NMA1062 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 15793880 Common - membrane protein NMA0915 16 COG1714 COG1714, Predicted membrane protein/domain Function unknown 15793729 Common - membrane protein NMA0754 59 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 15793307 Common pilB trifunctional thioredoxin/methionine sulfoxide reductase A/B protein NMA0290 207 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15794729 Common - hypothetical protein NMA1840 6 None None None 15794827 Common ldhA D-lactate dehydrogenase NMA1944 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 161353788 Common murC UDP-N-acetylmuramate--L-alanine ligase NMA2061 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 15794671 Common - predicted inner membrane peptidase NMA1778 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15793101 Common pdxA pyridoxal phosphate biosynthetic protein NMA0072 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 15794840 Common fabF2 3-oxoacyl-(acyl carrier protein) synthase II NMA1957 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15794720 Common - hypothetical protein NMA1830 21 COG4379 COG4379, Mu-like prophage tail protein gpP General function prediction only 15794573 Pathogen - membrane protein NMA1680 1 None None None 15793699 Common - transmembrane transport protein NMA0722 105 COG1620 LldP, L-lactate permease Energy production and conversion 15794208 Common - hypothetical protein NMA1278 74 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15793683 Common - hypothetical protein NMA0704 101 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15793531 Common fabD acyl-carrier-protein S-malonyltransferase NMA0536 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 15793650 Common - peptidase NMA0665 106 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 15794659 Common ilvI acetolactate synthase isozyme III large subunit NMA1766 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15794875 Common natD' periplasmic type I secretion system protein NMA1995 29 None None None 15793770 Common - hypothetical protein NMA0796 130 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 15794535 Common - insertion element IS1106 transposase NMA1641 31 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15794213 Common - phage transposase NMA1284 22 None None None 15794604 Common rpiA ribose-5-phosphate isomerase A NMA1711 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 15793463 Common - truncated IS1106A2 transposase NMA0461 13 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15794691 Common - invertase/transposase NMA1800 74 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793593 Common - hypothetical protein NMA0603 8 None None None 15793762 Common - hypothetical protein NMA0787 19 None None None 15793662 Common - hypothetical protein NMA0679a 20 COG2850 COG2850, Uncharacterized conserved protein Function unknown 15793563 Common - protein-L-isoaspartate O-methyltransferase NMA0572 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 15794070 Common - lipoprotein NMA1123 26 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 15794492 Common gyrA DNA gyrase subunit A NMA1599 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15793259 Common etfA electron transfer flavoprotein alpha-subunit NMA0241 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 15793808 Common hisF imidazole glycerol phosphate synthase subunit HisF NMA0838 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 15794217 Pathogen - hypothetical protein NMA1288 1 None None None 15794117 Pathogen - hypothetical protein NMA1172 1 None None None 15793093 Common fur ferric uptake regulation protein NMA0064 200 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15794393 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase NMA1493 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 15793376 Pathogen - integral membrane protein NMA0368 1 None None None 15794847 Common gdhA glutamate dehydrogenase NMA1964 174 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 15794143 Common - IS1106A3 transposase NMA1199 39 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15793536 Common plsX fatty acid/phospholipid synthesis protein NMA0542 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 15793551 Common mlp lipoprotein NMA0557 9 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 15794622 Common - hypothetical protein NMA1729 74 COG1881 COG1881, Phospholipid-binding protein General function prediction only 15793190 Common fmt methionyl-tRNA formyltransferase NMA0163 221 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 15793324 Common - hypothetical protein NMA0312 2 None None None 15793112 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase NMA0083 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 15794164 Common - hypothetical protein NMA1222 8 None None None 15793963 Common ftsH ATP-dependent zinc metallopeptidase NMA1007 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15793854 Common nusB transcription antitermination protein NusB NMA0885 122 COG0781 NusB, Transcription termination factor Transcription 15794608 Common - integral membrane protein NMA1715 83 None None None 15793700 Common - UDP-2,3-diacylglucosamine hydrolase NMA0723 76 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 15794371 Common - hypothetical protein NMA1470 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 15794222 Common - phage anti-repressor protein NMA1293 20 COG3561 COG3561, Phage anti-repressor protein Transcription 15795057 Common - DNA transport competence protein NMA2187 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 15793631 Common - hypothetical protein NMA0645 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 15793784 Common - hypothetical protein NMA0811 163 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 15794851 Common mtrE outer membrane lipoprotein NMA1968 122 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15794897 Common speA arginine decarboxylase NMA2017 104 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 15794644 Common - gntR-family transcriptional regulator NMA1751 97 COG1802 GntR, Transcriptional regulators Transcription 15794678 Common - hypothetical protein NMA1785 77 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15794016 Pathogen - hypothetical protein NMA1067 1 None None None 15793688 Common - periplasmic serine protease NMA0710 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15794296 Common - transcriptional regulator NMA1375 38 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 15795015 Common - YciI-like protein NMA2144 70 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 15794754 Common - integral membrane protein NMA1866 7 None None None 15793504 Common - inner membrane transport protein NMA0505 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 15794917 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ NMA2037 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 15794324 Common ruvB Holliday junction DNA helicase B NMA1412 230 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 15794362 Common - integral membrane protein NMA1460 15 None None None 15793853 Common pyrC dihydroorotase NMA0884 96 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 15794641 Common glnS glutaminyl-tRNA synthetase NMA1748 242 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15793122 Common - zinc transporter ZupT NMA0093 99 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 15794077 Pathogen - membrane protein NMA1131a 1 None None None 15793830 Common apaH diadenosine tetraphosphatase NMA0860 92 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 15794455 Pathogen - hypothetical protein NMA1562 1 None None None 15794634 Common - remnant of insertion element IS1106 transposase NMA1741 13 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15793199 Pathogen - integral membrane protein NMA0171A 1 None None None 15794631 Common - insertion element IS1106 transposase NMA1738 35 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15793343 Common - hypothetical protein NMA0331 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15793295 Pathogen - lipoprotein NMA0277 1 None None None 15794938 Common ddl D-alanine--D-alanine ligase NMA2060 216 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 15793177 Common tufA2 elongation factor Tu NMA0149 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15795010 Common - tRNA-dihydrouridine synthase A NMA2139 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15793134 Common rpsM 30S ribosomal protein S13 NMA0106 238 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 15793849 Common accD acetyl-CoA carboxylase subunit beta NMA0880 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 15793519 Common glyQ glycyl-tRNA synthetase subunit alpha NMA0521 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 15794137 Common - hypothetical protein NMA1193 18 COG3422 COG3422, Uncharacterized conserved protein Function unknown 15793478 Common - para-aminobenzoate synthase component I NMA0477 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15793318 Common - protease NMA0305 168 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15793978 Common - multidrug efflux protein NMA1022 177 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15794951 Common - hypothetical protein NMA2075 130 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 15794400 Common - modification methylase NMA1500 131 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15794468 Common xseA exodeoxyribonuclease VII large subunit NMA1575 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 15793628 Common - hypothetical protein NMA0640 26 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15794311 Common lon ATP-dependent protease NMA1398 210 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 15793621 Common - hypothetical protein NMA0633 49 COG2501 COG2501, Uncharacterized conserved protein Function unknown 15793895 Common pheT phenylalanyl-tRNA synthetase subunit beta NMA0937 245 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 15793943 Common - hypothetical protein NMA0986 15 COG4390 COG4390, Uncharacterized protein conserved in bacteria Function unknown 15793793 Common amtB ammonium transporter NMA0820 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 15793596 Pathogen - hypothetical protein NMA0606 1 None None None 15793244 Common - IS1106 transposase NMA0221 42 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15793427 Common - psedouridine synthase NMA0422 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15793079 Common pglA glycosyltransferase NMA0048 175 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15794985 Pathogen mafA2 adhesin MafA2 NMA2112 1 None None None 15793751 Common - cell-surface protein NMA0776 4 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 15794097 Common lpdA3 dihydrolipoamide dehydrogenase NMA1151 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15794120 Common pntB pyridine nucleotide transhydrogenase NMA1175 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 15793840 Pathogen - hypothetical protein NMA0871 1 None None None 15793915 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine- pyrophosphokinase NMA0958 194 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 15794793 Common - IS1016 transposase NMA1907b 4 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794943 Common - periplasmic protein NMA2065 4 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15793745 Pathogen - hypothetical protein NMA0770 1 None None None 15793480 Common aldA aldehyde dehydrogenase A NMA0480 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15794152 Pathogen - hypothetical protein NMA1208 1 None None None 15793238 Common proC pyrroline-5-carboxylate reductase NMA0215 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 15793448 Common - hydroxyacylglutathione hydrolase NMA0444 160 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15793674 Pathogen - hypothetical protein NMA0694 1 None None None 15793444 Common - hypothetical protein NMA0439 8 None None None 15794110 Common trpD anthranilate phosphoribosyltransferase NMA1164 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 15794507 Common - dehydrogenase fragment NMA1613 72 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15794289 Common - membrane protein NMA1368 45 COG3658 COG3658, Cytochrome b Energy production and conversion 15794347 Common fpr ferredoxin--NADP reductase NMA1442 111 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 15793886 Common hemH ferrochelatase NMA0927 155 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 15794026 Common - hypothetical protein NMA1078 3 None None None 15793141 Common rplR 50S ribosomal protein L18 NMA0113 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 15794421 Common - ftsK-like cell division/stress response protein NMA1527 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15793148 Common rpsQ 30S ribosomal protein S17 NMA0120 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 15795083 Common - hypothetical protein NMA2214 3 None None None 15794668 Common - insertion element IS1106A3 transposase NMA1775 22 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15795076 Common - solvent tolerance protein NMA2207 116 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 15794776 Common - hypothetical protein NMA1888 74 COG1262 COG1262, Uncharacterized conserved protein Function unknown 15793904 Common - regulatory protein NMA0946 136 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15794739 Common - hypothetical protein NMA1851 27 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 15793658 Common recG DNA helicase NMA0675 216 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 15794855 Pathogen - hypothetical protein NMA1972 1 None None None 161353787 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase NMA2084 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 15794664 Common hisC histidinol-phosphate aminotransferase NMA1771 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 15794609 Common - inner membrane protein NMA1716 26 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 15794915 Common - hypothetical protein NMA2035 4 COG0730 COG0730, Predicted permeases General function prediction only 15795065 Common - hypothetical protein NMA2196 25 COG2259 COG2259, Predicted membrane protein Function unknown 15794803 Common rpoZ DNA-directed RNA polymerase omega chain NMA1918 111 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 15794067 Common - oxidoreductase NMA1120 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 15793512 Common atpE ATP synthase C chain NMA0514 55 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 15793633 Common aroB 3-dehydroquinate synthase NMA0647 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 15793173 Common rplA 50S ribosomal protein L1 NMA0145 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 15794970 Common - integral membrane efflux protein NMA2095 137 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 15794052 Common dnaB replicative DNA helicase NMA1105 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15794340 Pathogen - hypothetical protein NMA1435 1 None None None 15794378 Common - polysaccharide modification protein NMA1478 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 15794908 Common amiC N-acetylmuramoyl-L-alanine amidase NMA2028 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15794265 Common - hypothetical protein NMA1341 2 None None None 15794050 Common - integral membrane protein NMA1102 15 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 15793404 Pathogen - hypothetical protein NMA0396 1 None None None 15793807 Common hisI phosphoribosyl-AMP cyclohydrolase NMA0837 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 15793356 Common obgE GTPase ObgE NMA0345 232 COG0536 Obg, Predicted GTPase General function prediction only 15793953 Common - hypothetical protein NMA0996 50 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 15793541 Common - hypothetical protein NMA0547 188 COG0313 COG0313, Predicted methyltransferases General function prediction only 15795032 Common - octaprenyl-diphosphate synthase NMA2161 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15793708 Common - integral membrane protein NMA0732 6 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 15794133 Pathogen - hypothetical protein NMA1189 1 None None None 15793363 Pathogen - integral membrane protein NMA0353 1 COG1714 COG1714, Predicted membrane protein/domain Function unknown 15793464 Common polA DNA polymerase I NMA0462 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 15795038 Pathogen - hypothetical protein NMA2167 1 None None None 15793048 Common nuoF NADH dehydrogenase I chain F NMA0014 165 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 15794253 Common - hypothetical protein NMA1326 22 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 15794518 Pathogen - integral membrane protein NMA1624 1 None None None 15793193 Pathogen - integral membrane protein NMA0166 1 None None None 15793758 Pathogen - hypothetical protein NMA0783 1 None None None 15793221 Common ctrC capsule polysaccharide export inner-membrane protein NMA0196 47 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15793865 Pathogen folI transcriptional regulator NMA0897 1 None None None 15795053 Pathogen - hypothetical protein NMA2182 1 None None None 15793576 Common - hypothetical protein NMA0585 147 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 15794809 Pathogen - hypothetical protein NMA1924 2 None None None 15793247 Common - lipoprotein NMA0225 131 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 15793636 Common pilP pilus assembly protein NMA0651 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 15794704 Common - IS1655 transposase NMA1814 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 15793431 Pathogen - hypothetical protein NMA0426A 1 None None None 15793899 Pathogen - hypothetical protein NMA0941 1 None None None 15793046 Pathogen - hypothetical protein NMA0012 1 None None None 15794267 Common fdx ferredoxin NMA1344 62 COG0633 Fdx, Ferredoxin Energy production and conversion 15795046 Common vapA virulence associated protein NMA2175 13 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15794830 Common ans L-asparaginase NMA1947 119 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 15794186 Pathogen opcA outer membrane protein precursor NMA1251 1 None None None 15793124 Pathogen - hypothetical protein NMA0095 1 None None None 15794735 Common - hypothetical protein NMA1847 17 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 15793646 Common - lipid A biosynthesis lauroyl acyltransferase NMA0662 84 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 15794629 Common dnaG DNA primase NMA1736 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15793228 Common galE UDP-glucose 4-epimerase NMA0203 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 15793074 Common pyrD dihydroorotate dehydrogenase 2 NMA0042 236 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 15793108 Common - integral membrane protein NMA0079 19 COG1289 COG1289, Predicted membrane protein Function unknown 15793735 Common hemA glutamyl-tRNA reductase NMA0760 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 15793608 Common - translation-associated GTPase NMA0618 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 15794976 Common - putative ABC transporter ATP-binding protein NMA2101 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15794129 Common - transposase NMA1185 57 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793443 Pathogen - hypothetical protein NMA0438 1 None None None 15793333 Pathogen - hypothetical protein NMA0321 1 None None None 15794888 Common - hypothetical protein NMA2008 39 COG2229 COG2229, Predicted GTPase General function prediction only 15793740 Common - lipoprotein NMA0765 27 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 15793516 Common atpG F0F1 ATP synthase subunit gamma NMA0518 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 15794239 Pathogen - hypothetical protein NMA1310 1 None None None 15794304 Common - membrane protein NMA1383 6 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15793069 Common - hypothetical protein NMA0037 7 COG4304 COG4304, Uncharacterized protein conserved in bacteria Function unknown 15794651 Common pepA aminopeptidase A NMA1758 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 15793882 Common rpoH RNA polymerase factor sigma-32 NMA0917 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15794105 Common uvrA excinuclease ABC subunit A NMA1159 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 15793828 Common - hypothetical protein NMA0858 2 None None None 15793921 Common xerD integrase/recombinase NMA0964 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15793277 Common - transmembrane transport protein NMA0259 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15793234 Pathogen - hypothetical protein NMA0210 1 None None None 15793326 Pathogen - hypothetical protein NMA0314 1 None None None 15794824 Common parE DNA topoisomerase IV subunit B NMA1941 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15794807 Pathogen - hypothetical protein NMA1922 1 None None None 15793396 Common - DNA ligase NMA0388 30 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 15793166 Common - hypothetical protein NMA0138 3 None None None 15793260 Common etfB electron transfer flavoprotein beta-subunit NMA0242 146 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 15793400 Common ptsI phosphoenolpyruvate-protein phosphotransferase NMA0392 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 15793992 Common nmgI type II restriction endonuclease NMA1036 24 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 15794663 Common hisD histidinol dehydrogenase NMA1770 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 15794758 Common - hypothetical protein NMA1870 2 None None None 15793588 Pathogen - hypothetical protein NMA0598 1 None None None 15794501 Common glk glucokinase NMA1607 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 15794863 Common - hypothetical protein NMA1981 56 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 15794224 Pathogen - hypothetical protein NMA1295 1 None None None 15795094 Common xseB exodeoxyribonuclease small subunit NMA2225 57 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 15794482 Common - hypothetical protein NMA1589 10 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 15794593 Common - outer membrane substrate binding protein NMA1700 26 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15793612 Common ileS isoleucyl-tRNA synthetase NMA0622 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793420 Common - hypothetical protein NMA0415 40 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 15794614 Common - transferase NMA1721 94 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 15794899 Common aspS aspartyl-tRNA synthetase NMA2019 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15795068 Pathogen - hypothetical inner membrane protein NMA2199a 1 None None None 15793872 Common comA competence protein NMA0906 151 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 15794627 Common - hypothetical protein NMA1734 5 None None None 15793311 Common - hypothetical protein NMA0296 120 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 15793668 Common - hypothetical protein NMA0688 85 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 15793185 Common dprA DprA homolog NMA0158 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 15793727 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A NMA0752 43 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 15794856 Common - hypothetical integral membrane protein NMA1973 40 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 15793887 Common tgt queuine tRNA-ribosyltransferase NMA0928 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 15794173 Pathogen - hypothetical protein NMA1231 2 None None None 15794713 Common - hypothetical protein NMA1823 5 None None None 15794487 Common - NifS-like aminotranfserase NMA1594 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 15793305 Common - integral membrane protein NMA0288 179 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15793171 Common rplL 50S ribosomal protein L7/L12 NMA0143 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 15794924 Common - hypothetical integral membrane protein NMA2046 56 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 15793051 Common nuoC NADH dehydrogenase subunit C NMA0017 170 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 15794797 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase NMA1912 216 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15794727 Pathogen - hypothetical protein NMA1837 1 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 15794768 Pathogen - hypothetical protein NMA1880 1 None None None 15794786 Common - sodium:alanine symporter NMA1901 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 15793215 Common rfbC2 dTDP-D-glucose 4,6-dehydratase NMA0187 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 15794277 Common mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase NMA1356 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 15794680 Common alaS alanyl-tRNA synthetase NMA1788 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15793491 Common - hypothetical protein NMA0492 14 COG0824 FcbC, Predicted thioesterase General function prediction only 15794958 Common putP sodium/proline symporter NMA2083 178 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 15793265 Common mutS DNA mismatch repair protein NMA0247 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15794437 Common - hypothetical protein NMA1544 5 None None None 15794790 Common - AsnC-family transcriptional regulator NMA1905 166 COG1522 Lrp, Transcriptional regulators Transcription 15794575 Common trpS tryptophanyl-tRNA synthetase NMA1682 227 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15794901 Common - phopholipase NMA2021 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 15793058 Pathogen - hypothetical protein NMA0024 1 None None None 15793473 Common groES co-chaperonin GroES NMA0472 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 15793601 Common - hypothetical protein NMA0611 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15794993 Pathogen - hypothetical protein NMA2121 1 None None None 15793877 Common - lipoprotein NMA0912 31 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 15794448 Common aceF dihydrolipoamide acetyltransferase NMA1555 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 15794192 Common fbp fructose-1,6-bisphosphatase NMA1259 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 15794301 Common - hypothetical protein NMA1380 56 COG2921 COG2921, Uncharacterized conserved protein Function unknown 15795026 Common pilG pilus-assembly protein NMA2155 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 15793508 Pathogen - hypothetical protein NMA0510 2 None None None 15794258 Common - periplasmic protein NMA1332 22 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 15793710 Common - IS1106A3 transposase NMA0734 35 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15794968 Common pgm2 beta-phosphoglucomutase NMA2093 100 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15793269 Common - periplasmic protein NMA0251 58 COG1434 COG1434, Uncharacterized conserved protein Function unknown 15794465 Common pdxH pyridoxamine 5'-phosphate oxidase NMA1572 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 15794812 Common - hypothetical integral membrane protein NMA1929 63 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 15793296 Common - membrane-bound lytic murein transglycosylase NMA0279 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 15793936 Common pilT2 pilus retraction protein NMA0979 217 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 15793856 Common - hypothetical protein NMA0887 7 COG4859 COG4859, Uncharacterized protein conserved in bacteria Function unknown 15794024 Pathogen - hypothetical protein NMA1076 1 None None None 15794718 Common - hypothetical protein NMA1828 7 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 15794636 Common fadD long-chain-fatty-acid--CoA-ligase NMA1743 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15794326 Pathogen - periplasmic protein NMA1414 1 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 15793961 Common - hypothetical protein NMA1005 69 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 15793252 Common - RNA polymerase sigma factor NMA0230 146 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 15793151 Common rpsC 30S ribosomal protein S3 NMA0123 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 15795072 Common purB adenylosuccinate lyase NMA2203 235 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 15793320 Pathogen - hypothetical protein NMA0308 1 None None None 15793246 Common prfB peptide chain release factor 2 NMA0224 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 15794354 Common gshA glutamate--cysteine ligase NMA1449 27 None None None 15793569 Common - araC-family transcriptional regulator NMA0578 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15793635 Common pilQ pilus secretin NMA0650 138 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 15793520 Common - hypothetical protein NMA0522 5 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 15793940 Common - haemolysin NMA0983 7 COG3042 Hlx, Putative hemolysin General function prediction only 15794481 Common truB tRNA pseudouridine synthase B NMA1588 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 15793477 Common - hypothetical periplasmic protein NMA0476 12 None None None 15794761 Pathogen - hypothetical protein NMA1873 1 None None None 15793461 Common - IS1106A3 transposase NMA0458 36 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15794294 Pathogen - hypothetical protein NMA1373 1 None None None 15794079 Common efp elongation factor P NMA1133 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15794661 Common hisG ATP phosphoribosyltransferase catalytic subunit NMA1768 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 15793110 Common uppS undecaprenyl diphosphate synthase NMA0081 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15794069 Common pip proline iminopeptidase NMA1122 113 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15794633 Common lbpB lactoferrin-binding protein NMA1740 4 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 15794453 Common - SpoU methylase family protein NMA1560 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 15795095 Common ispA geranyltranstransferase NMA2226 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15793205 Common pykA pyruvate kinase NMA0177 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 15795055 Common - IS1016C2 transposase NMA2185 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15794018 Pathogen - hypothetical protein NMA1070 1 None None None 15793721 Common apbE thiamine biosynthesis protein NMA0746 139 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 15793867 Common - amino acid permease ATP-binding protein NMA0900 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15793746 Pathogen - hypothetical protein NMA0771 1 None None None 15793120 Common - amino-acid transporter NMA0091 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 15794865 Common exbD biopolymer transport protein NMA1983 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 15793832 Common nspA outer membrane protein NMA0862 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15793192 Common - periplasmic protein NMA0165 46 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 15793772 Common - two-component system regulator NMA0798 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15794606 Common - hypothetical protein NMA1713 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 15793934 Common lepA GTP-binding protein LepA NMA0977 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 161353791 Common ruvC Holliday junction resolvase NMA1631 192 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 15794384 Pathogen - hypothetical protein NMA1484 1 None None None 15793561 Common tpiA triosephosphate isomerase NMA0570 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 15794107 Common - outer-membrane receptor protein NMA1161 65 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15793787 Pathogen - hypothetical protein NMA0814 1 None None None 15793394 Common - periplasmic protein NMA0386 184 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 15794982 Common hemN coproporphyrinogen III oxidase NMA2108 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15793298 Common - hypothetical protein NMA0281 29 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 15794099 Common sucC succinyl-CoA synthetase subunit beta NMA1153 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 15793106 Common gidB glucose-inhibited division protein B NMA0077 205 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 15793614 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NMA0624 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 15793119 Common lpxA UDP-N-acetylglucosamine acyltransferase NMA0090 154 COG1043 LpxA, Acyl- acyl carrier protein 15793768 Common rimM 16S rRNA-processing protein NMA0794 183 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 15793417 Common - glucokinase NMA0412 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 15794625 Common - hypothetical protein NMA1732 17 None None None 15794693 Common parC DNA topoisomerase IV subunit A NMA1802 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15794035 Common - spermidine synthase NMA1087 59 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 15793383 Common gpsA glycerol-3-phosphate dehydrogenase NMA0375 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15793183 Common topA DNA topoisomerase I NMA0156 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15794260 Common - periplasmic protein NMA1335 29 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 15794547 Common - methyltransferase NMA1653 88 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 15793534 Pathogen - hypothetical protein NMA0540 1 None None None 15793791 Common - polyamine permease inner membrane protein NMA0818 158 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 15794602 Common - binding-protein-dependent transport systems inner membrane protein NMA1709 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15793661 Common - hypothetical protein NMA0678 6 COG2850 COG2850, Uncharacterized conserved protein Function unknown 15794533 Common - integral membrane protein NMA1639 24 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 15794219 Pathogen - hypothetical protein NMA1290 1 None None None 15794395 Common eno phosphopyruvate hydratase NMA1495 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 15794849 Common - integral membrane protein NMA1966 40 COG1620 LldP, L-lactate permease Energy production and conversion 15794215 Common - phage transposase NMA1286 30 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 15793697 Pathogen - hypothetical protein NMA0720 2 None None None 15794115 Pathogen - integral membrane protein NMA1170 1 None None None 15794001 Pathogen - membrane protein NMA1051 1 None None None 15793450 Common glnB nitrogen regulatory protein P-II 1 NMA0447 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15795061 Common - thiol:disulphide interchange protein NMA2191 69 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15794349 Common - P-type cation-transporting ATPase NMA1444 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15794210 Pathogen - hypothetical protein NMA1281 1 None None None 15794941 Common ftsW cell division protein NMA2063 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15793694 Common - hypothetical protein NMA0717 200 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 15795078 Common - thiol:disulphide interchange protein NMA2209 40 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15794584 Common - acyl-CoA hydrolase NMA1691 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 15794778 Common - hypothetical protein NMA1892 64 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15794886 Common - hypothetical protein NMA2006 22 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 15795019 Common - hypothetical protein NMA2148 61 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 15793672 Common - hypothetical protein NMA0692 7 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 15793656 Common - glutaredoxin NMA0673 116 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 15793906 Common - hypothetical protein NMA0948 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 15793589 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase NMA0599 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 15794159 Common - IS1106A3 transposase NMA1217 35 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 15794494 Pathogen - transposase fragment NMA1601 1 None None None 15794145 Common - rubredoxin NMA1201 120 COG1773 COG1773, Rubredoxin Energy production and conversion 15793082 Pathogen - hypothetical protein NMA0051 1 None None None 15793232 Common - integral membrane protein NMA0207 42 COG1297 COG1297, Predicted membrane protein Function unknown 15793971 Common - NAD(P)H-flavin oxidoreductase NMA1015 91 COG0778 NfnB, Nitroreductase Energy production and conversion 15793406 Common porB porin, major outer membrane protein P.I NMA0398 42 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15794426 Common - hypothetical protein NMA1533 123 COG0730 COG0730, Predicted permeases General function prediction only 15794342 Common - lysR-family transcriptional regulator NMA1437 186 COG0583 LysR, Transcriptional regulator Transcription 15793931 Common cysK cysteine synthase NMA0974 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 15793434 Common vsr patch repair protein NMA0429 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 15795014 Common - hypothetical protein NMA2143 68 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 15793274 Common - hypothetical protein NMA0256 58 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 15794552 Common recA recombinase A NMA1658 229 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 15794013 Common - membrane protein NMA1064 58 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 15793354 Common - truncated IS1016 transposase NMA0344 4 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 15793927 Common - hypothetical protein NMA0970 29 COG2836 COG2836, Uncharacterized conserved protein Function unknown 15794591 Common - integral membrane protein (CstA-like) NMA1698 108 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 15794931 Common - hypothetical protein NMA2053 104 COG0730 COG0730, Predicted permeases General function prediction only 15794837 Common - integral membrane protein NMA1954 27 COG4648 COG4648, Predicted membrane protein Function unknown 15794745 Pathogen - hypothetical protein NMA1857 1 None None None 15794059 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase NMA1112 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism 15793341 Pathogen - integral membrane protein NMA0329 1 None None None 15794466 Common - pseudouridine synthase NMA1573 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15794413 Common esd esterase D NMA1519 96 COG0627 COG0627, Predicted esterase General function prediction only 15794418 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NMA1524 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 15793821 Common ppa inorganic pyrophosphatase NMA0851 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 15794245 Common - hypothetical protein NMA1316 14 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 15794127 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NMA1182 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 15794280 Common - hypothetical protein NMA1359 25 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 15793945 Common hemD uroporphyrinogen-III synthase NMA0988 36 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 15793062 Common - hypothetical protein NMA0029 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 15794511 Common sodC superoxide dismutase NMA1617 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 15793348 Pathogen - periplasmic protein NMA0338 1 None None None 15793158 Common - hypothetical protein NMA0131 13 COG3596 COG3596, Predicted GTPase General function prediction only 15794949 Common - small periplasmic protein NMA2073 4 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 15794411 Common - transcriptional regulator NMA1517 78 COG0789 SoxR, Predicted transcriptional regulators Transcription 15794230 Common - hypothetical protein NMA1301 15 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 15793753 Pathogen - hypothetical protein NMA0778 1 None None None 15793482 Common - hypothetical protein NMA0482 6 None None None 15794445 Common - hydrolase NMA1552 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 15795085 Common - hydrolase NMA2216 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only