Clostridium acetobutylicum ATCC 824, complete genome NC_003030 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 15894240 Common - hypothetical protein CAC0953 2 None None None 15894369 Common - Beta-glucosidase family protein CAC1084 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15894638 Common - Predicted xylanase/chitin deacetylase CAC1359 101 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15894130 Common - Ribonuclease precursor (barnase), secreted. CAC0843 10 COG4290 COG4290, Guanyl-specific ribonuclease Sa Nucleotide transport and metabolism 15893356 Nonpathogen - hypothetical protein CAC0059 1 None None None 15895167 Common - ClpP family serine protease, possible phage related CAC1893 186 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15896684 Common bltR Multidrug-efflux transporter transcription regulator, BltR CAC3443 78 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 15896449 Common ftsH ATP-dependent Zn protease, FTSH CAC3202 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15894587 Nonpathogen - Uncharacterized protein similar to a protein from Cylindrotheca fusiformis plasmid (GI:99322) CAC1305 1 None None None 15895147 Common repB Replication initiation protein REP CAC1872 7 COG5655 COG5655, Plasmid rolling circle replication initiator protein and truncated derivatives DNA replication, recombination, and repair 15893745 Common - Predicted ATP transporter permease component CAC0454 62 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15893667 Common - N-dimethylarginine dimethylaminohydrolase (similar to ykgA B.subtilis) CAC0376 36 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 15896773 Common - hypothetical protein CAC3537 106 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 15894275 Nonpathogen - Probably membrane protein CAC0988 12 None None None 15894259 Common citC Isocitrate dehydrogenase CAC0972 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 15893457 Common - Transcriptional regulator MarR/EmrR family CAC0162 17 COG1846 MarR, Transcriptional regulators Transcription 15895504 Common - Uncharacterized conserved protein of YjeB/RRF2 family CAC2236 133 COG1959 COG1959, Predicted transcriptional regulator Transcription 15893854 Common - Response regulator (REC, HTH domains) CAC0564 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15894765 Common - Uncharacterized protein, ortholog of YKUS B.subtilis CAC1486 7 None None None 15893339 Common - Uncharacterized small conserved protein, homolog of yfjA/yukE B.subtilis CAC0041 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15895810 Nonpathogen - Reductase/isomerase/elongation factor common domain CAC2548 1 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 15893525 Common - PTS system, IIA component CAC0233 134 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15894398 Common - hypothetical protein CAC1113 4 None None None 15896937 Nonpathogen - Hypothetical protein, CF-12 family CAC3706 1 None None None 15893890 Common - Unchracterized membrane protein, possible permease CAC0601 21 None None None 15896100 Common prfB peptide chain release factor 2 CAC2845 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 15896333 Common - Thioredoxin reductase CAC3082 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15896218 Common lacF PTS system lactose-specific enzyme IIA CAC2965 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 15894321 Nonpathogen - hypothetical protein CAC1034 1 None None None 15895697 Common - Predicted permease CAC2432 78 COG0628 PerM, Predicted permease General function prediction only 15895082 Common - bifunctional riboflavin kinase/FMN adenylyltransferase CAC1806 211 COG0196 RibF, FAD synthase Coenzyme metabolism 15896111 Common - Spore protease GPR related protein, YYAC B.subtilis ortholog CAC2857 14 None None None 15896200 Common topB DNA topoisomerase III CAC2947 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15894383 Common polA DNA polymerase I CAC1098 223 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 15896662 Common - Acyl carrier protein phosphodiesterase CAC3421 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 15895976 Common - Ethanolamin permease CAC2719 175 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 15894809 Common - hypothetical protein CAC1531 25 COG2461 COG2461, Uncharacterized conserved protein Function unknown 15895778 Common - Predicted membrane protein CAC2513 2 None None None 15893754 Common - Serine protease Do (heat-shock protein) CAC0463 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15894597 Common - Potassium channel subunit CAC1317 117 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 15896090 Common gntP Gluconate permease, gntP CAC2835 66 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 15895244 Nonpathogen - Hypothetical secreted protein CAC1973 1 None None None 15895539 Common - coproporphyrinogen III oxidase CAC2271 210 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15893730 Common - hypothetical protein CAC0439 1 None None None 15894490 Common - hypothetical protein CAC1207 2 None None None 15895755 Common - Xre family DNA-binding domain and TPR repeats containing protein CAC2490 21 None None None 15894598 Nonpathogen - hypothetical protein CAC1318 3 None None None 15896366 Common rpsE 30S ribosomal protein S5 CAC3116 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 15895051 Nonpathogen - Predicted membrane protein CAC1775 1 None None None 15894003 Common vacB FUSION ribonuclease and ribosomal protein S1 domain CAC0715 211 COG0557 VacB, Exoribonuclease R Transcription 15894218 Common - Cysteine synthase CAC0931 228 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 15896680 Common - Uncharacterized conserved membrane protein, YGAE B.subtilis homolog CAC3439 3 COG4129 COG4129, Predicted membrane protein Function unknown 15896736 Common - Predicted endonuclease CAC3499 22 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 15894474 Nonpathogen - hypothetical protein CAC1191 1 None None None 15896413 Common - hypothetical protein CAC3165 3 None None None 15894330 Common - Xre family DNA-binding domain and TPR-repeat containing protein CAC1043 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15896742 Common - Multimeric flavodoxin WrbA family protein CAC3505 49 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15895760 Common - Predicted transcriptional regulator CAC2495 63 COG1476 COG1476, Predicted transcriptional regulators Transcription 15895606 Common - Uncharacterized protein, YBBK B.subtilis ortholog CAC2339 65 COG1683 COG1683, Uncharacterized conserved protein Function unknown 15893552 Common nifV Homocitrate syntase, omega subunit nifV (nivO) CAC0260 185 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15896393 Common rplL Ribosomal protein L7/L12 CAC3145 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 15894285 Common - Homoserine dehydrogenase CAC0998 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 15893500 Nonpathogen - Hypothetical protein, CF-6 family CAC0207 1 None None None 15895746 Common - topology modulation protein CAC2481 46 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 15895817 Nonpathogen - hypothetical protein CAC2555 2 None None None 15894858 Common - hypothetical protein CAC1580 1 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 15895637 Common hslO Hsp33-like chaperonin CAC2370 132 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 15896575 Common - Predicted amidohydrolase (dihydroorothase family) CAC3332 58 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 15893878 Common birA Biotin-(acetyl-CoA carboxylase)ligase CAC0589 197 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 15896925 Nonpathogen - Predicted membrane protein CAC3693 1 None None None 15893441 Common - Related to ABC transporter permease component CAC0146 3 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15896310 Common - Sugar transferase CAC3059 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 15895615 Common - Glycosyltransferase CAC2348 166 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894987 Common - Fe-S oxidoreductase, related to NifB/MoaA family with PDZ N-terminal domain CAC1710 31 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 15895182 Nonpathogen - Predicted membrane protein CAC1908 1 None None None 15896918 Common - Metallo-beta-lactamase superfamily hydrolase CAC3686 22 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15894552 Nonpathogen - hypothetical protein CAC1270 1 None None None 15896705 Common - Transcriptional regulator, LysR family CAC3466 186 COG0583 LysR, Transcriptional regulator Transcription 15895806 Common etfB Electron-transferring flavoprotein small subunit CAC2544 151 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 15894870 Common - Predicted permease, YCGR B.subtilis ortholog CAC1592 101 COG0701 COG0701, Predicted permeases General function prediction only 15894621 Common araA L-arabinose isomerase CAC1342 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 15895901 Common - hypothetical protein CAC2643 1 None None None 15895780 Nonpathogen - hypothetical protein CAC2515 1 None None None 15894112 Common - Endoglucanase family 5 CAC0825 14 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 15896053 Common - NADH:flavin oxidoreductase CAC2798 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15894592 Nonpathogen - hypothetical protein CAC1312 1 None None None 15894894 Nonpathogen - hypothetical protein CAC1616 1 None None None 15893877 Common - hypothetical protein CAC0588 7 None None None 15896656 Common - ABC-type multidrug/protein/lipid transport system, ATPase component CAC3415 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15894631 Common - Membrane associated chemotaxis sensory transducer protein (MSP domain and HAMP domain) CAC1352 169 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894100 Common - hypothetical protein CAC0813 3 None None None 15896052 Nonpathogen - hypothetical protein CAC2797 1 None None None 15895789 Nonpathogen - hypothetical protein CAC2525 3 COG5617 COG5617, Predicted integral membrane protein Function unknown 15893921 Common - Predicted phosphatase CAC0633 5 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15894206 Common - Probably secreted sialidase; several ASP-boxes and dockerin domain CAC0919 25 None None None 15893431 Nonpathogen - hypothetical protein CAC0136 1 None None None 15893424 Common - hypothetical protein CAC0128 3 None None None 15893616 Common - TPR repeats containing protein CAC0324 4 None None None 15895894 Common - GTPase EngB CAC2636 198 COG0218 COG0218, Predicted GTPase General function prediction only 15895701 Common - hypothetical protein CAC2436 32 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 15895485 Common cheW Chemotaxis signal transduction protein CheW CAC2217 69 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15893705 Common - hypothetical protein CAC0414 1 None None None 15895908 Common pyrD dihydroorotate dehydrogenase 1B CAC2650 231 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 15894264 Common asnC Transcriptional regulator, Lrp family CAC0977 146 COG1522 Lrp, Transcriptional regulators Transcription 15894067 Common tyrZ tyrosyl-tRNA synthetase CAC0780 243 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15893847 Common - Predicted Zn-dependent protease with possible chaperone function CAC0557 74 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15895476 Common - Flagellin family protein, YVYC B.subtilis ortholog CAC2208 10 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 15896057 Common - Predicted phosphoglycerol transferase (alkaline phosphatase superfamily), YFNI B.subtilis CAC2802 66 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15893360 Common - hypothetical protein CAC0063 15 COG4926 PblB, Phage-related protein Function unknown 15893487 Common - Glycosyltransferase involved in cell wall biogenesis CAC0194 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15895106 Common - Protein containing Zn-finger domain CAC1831 2 None None None 15895037 Common - Signal peptidase I CAC1760 196 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15894036 Common - HD hydrolase superfamily protein CAC0749 47 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 15894147 Common - Two-component response regulator CAC0860 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15894186 Common - 3-dehydroquinate dehydratase CAC0899 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 15896910 Common kdpD Sensor protein KdpD (ATPase containing sensor domain and histidine kinase domain) CAC3678 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 15894933 Nonpathogen - Hypothetical protein, CF-39 family CAC1656 1 None None None 15896438 Common - ATP:guanido phosphotransferase CAC3190 25 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 15893967 Common - putative lipid kinase CAC0679 96 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 15893322 Common - Membrane protein, related to Actinobacillus protein (1944168) CAC0024 10 COG4713 COG4713, Predicted membrane protein Function unknown 15895885 Common trmB tRNA (guanine-N(7))-methyltransferase CAC2627 165 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 15896967 Common spoIIIJ putative inner membrane protein translocase component YidC CAC3736 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 15893786 Common thiC Thiamine monophosphate syntase CAC0495 209 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 15893416 Common - Membrane-associated methyl-accepting chemotaxis protein with HAMP domain CAC0120 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896115 Common spoIID Sporulation protein SpoIID CAC2861 45 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 15895868 Common - L-fucose isomerase related protein CAC2610 13 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 15895785 Nonpathogen - Hypothetical protein, CF-41 family CAC2521 1 None None None 15893307 Common - Uncharacterized conserved protein, ortholog of YRXA B.subtilis CAC0009 15 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 15893775 Common - Phosphomannomutase CAC0484 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15895496 Common - hypothetical protein CAC2228 1 None None None 15895388 Common - Predicted integral membrane protein, YggT family CAC2119 10 None None None 15893719 Common - Sugar permease CAC0428 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 15893928 Common - Predicted phoshohydrolase CAC0640 15 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 15893512 Nonpathogen - hypothetical protein CAC0220 1 None None None 15894017 Common - Predicted permease CAC0730 196 COG0628 PerM, Predicted permease General function prediction only 15893763 Common dnaK DnaK protein (heat shock protein), HSP70/DnaK family CAC0472 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15895238 Nonpathogen - Surface-layer related glycoprotein CAC1966 5 None None None 15896397 Common nusG transcription antitermination protein NusG CAC3149 215 COG0250 NusG, Transcription antiterminator Transcription 15895276 Common - Enzyme of siderophore/surfactin biosynthesis CAC2006 34 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 15895570 Common - Stage V sporulation AE, SpoVAE (fragment) CAC2303 15 None None None 15895381 Common uraA Uracil permease UraA/PyrP CAC2112 123 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15893723 Common - Methyl-accepting chemotaxis protein CAC0432 152 COG4936 PocR, Predicted sensor domain Signal transduction mechanisms / Transcription 15894746 Common - Transcriptional regulator, Lrp family CAC1467 134 COG1522 Lrp, Transcriptional regulators Transcription 15896276 Common - acyl-CoA thioesterase family protein CAC3024 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 15894002 Common secG preprotein translocase subunit SecG CAC0714 11 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 15895432 Common fliE flagellar hook-basal body protein FliE CAC2163 71 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 15894053 Common - Predicted transcriptional regulator (MerR family) CAC0766 97 COG0789 SoxR, Predicted transcriptional regulators Transcription 15896182 Common - Predicted membrane protein CAC2929 3 None None None 15896827 Common purA Adenylosuccinate synthase CAC3593 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 15894125 Common potC ABC-type spermidine/putrescine transport system, permease component II CAC0838 155 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 15896792 Nonpathogen - Probable S-layer protein CAC3556 1 None None None 15894523 Common maf Maf-like protein CAC1240 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 15895413 Common - Uncharacterized protein, YPFA B.subtilis ortholog CAC2144 11 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 15894455 Nonpathogen - Predicted integrase of XerC/XerD family, diverged CAC1172 1 None None None 15894239 Common - hypothetical protein CAC0952 1 None None None 15896553 Common - Predicted UDP-glucose 6-dehydrogenase CAC3310 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 15896039 Common - Signal peptidase type IV CAC2784 107 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15896503 Nonpathogen - hypothetical protein CAC3258 1 None None None 15894254 Common - Probably membrane protein CAC0967 2 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15896339 Common - NtrC family transcriptional regulator, ATPase domain fused to two PAS domains CAC3088 169 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 15896099 Common galT Galactose-1-phosphate uridylyltransferase CAC2844 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 15894315 Common - Hydrolase of alpha/beta superfamily, possible membrane associated lipase CAC1028 28 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 15896029 Common - Methyl-accepting chemotaxis protein with HAMP domain CAC2774 100 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894787 Common - Specialized sigma subunit of RNA polymerase CAC1509 64 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 15896405 Common trpA tryptophan synthase subunit alpha CAC3157 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 15895467 Common - hypothetical protein CAC2199 30 COG3882 FkbH, Predicted enzyme involved in methoxymalonyl-ACP biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 15896795 Common - ABC-type transporter, ATPase component CAC3560 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15894883 Common arbA Ketopantoate reductase CAC1605 127 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 15893840 Common - Possible sigma factor CAC0550 3 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15896781 Common - Methyl-accepting chemotaxis protein CAC3545 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15895269 Common - hypothetical protein CAC1999 2 None None None 15894151 Common - Histidine kinase-like ATPase CAC0864 149 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 15895090 Common pgsA Phosphatidylglycerophosphate synthase CAC1814 199 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15893942 Common - Sensory transduction histidine kinase CAC0654 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893958 Common - hypothetical protein CAC0670 4 None None None 15894878 Common - Methyl-accepting chemotaxis-like protein (chemotaxis sensory transducer) CAC1600 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893311 Common - Uncharacterized small conserved protein, ortholog of T.maritima (4981999) and P.abyssi (5457704) CAC0013 11 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 15894948 Common - recombination factor protein RarA CAC1671 237 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 15893835 Common - Uncharacterized small protein, homolog of Treponema (6136517) CAC0545 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 15893819 Common - Acetylxylan esterase related enzyme CAC0529 11 None None None 15893329 Common psdD phosphatidylserine decarboxylase CAC0031 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 15893343 Common - TPR-repeat-containing protein CAC0045 107 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15894343 Nonpathogen - hypothetical protein CAC1056 1 None None None 15893885 Common gerKA Spore germination protein. gerKA CAC0596 15 None None None 15896695 Common - Uncharacterized conserved predicted metal-binding protein CAC3455 17 COG3543 COG3543, Uncharacterized conserved protein Function unknown 15896323 Common - Mannose-1-phosphate guanylyltransferase CAC3072 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 15896220 Common - Alpha-acetolactate decarboxylase CAC2967 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 15896586 Common - Biotin synthase related domain containing protein CAC3343 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 15896715 Common - Predicted membrane protein CAC3478 1 None None None 15895660 Common - Transcriptional regulator, LysR family CAC2394 191 COG0583 LysR, Transcriptional regulator Transcription 15893574 Common - Cytosine/guanine deaminase related protein CAC0282 153 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15893976 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase CAC0688 65 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15893387 Common ilvC ketol-acid reductoisomerase CAC0091 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 15893635 Nonpathogen - hypothetical protein CAC0344 1 None None None 15895876 Common - Hypothetical protein, CF-17 family CAC2618 3 None None None 15894656 Common cbiD cobalt-precorrin-6A synthase CAC1377 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 15894566 Common prmA ribosomal protein L11 methyltransferase CAC1284 157 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 15895739 Common def N-formylmethionyl-tRNA deformylase CAC2474 210 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 15893656 Common - Phosphoglycerate dehydrogenase CAC0365 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15895159 Nonpathogen - hypothetical protein CAC1884 1 None None None 15894289 Common - nicotinate phosphoribosyltransferase CAC1002 118 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 15894848 Common bsaA Glutathione peroxidase CAC1570 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 15895030 Common - hypothetical protein CAC1753 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 15896649 Common - NADH oxidase (two distinct flavin oxidoreductase domains) CAC3408 234 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15896253 Common - Uncharacterized consrved protein, containing Zn finger CAC3001 20 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 15894269 Nonpathogen - hypothetical protein CAC0982 1 None None None 15894536 Common - Fe-S oxidoreductase CAC1254 66 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15896941 Common - Uncharacterized protein, YUKC B.subtilis homolog CAC3710 7 COG4499 COG4499, Predicted membrane protein Function unknown 15894714 Common - S-adenosylmethionine-dependent methyltransferase CAC1435 200 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 15895173 Common - hypothetical protein CAC1899 1 None None None 15894661 Common cbiH/cobJ precorrin-3B C17-methyltransferase CAC1382 175 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 15894196 Common - Methyl-accepting chemotaxis protein, contain HAMP domain CAC0909 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15895016 Common - Uncharacterized conserved protein (coiled-coil) CAC1739 28 None None None 15896305 Common - Phosphoheptose isomerase CAC3054 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 15893675 Common licB PTS system, cellobiose-specific component BII CAC0384 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 15894563 Common grpE Molecular chaperone GrpE CAC1281 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15894405 Common - Phage-related protein, YqbO B.subtilis homolog CAC1120 33 COG3953 COG3953, SLT domain proteins General function prediction only 15894400 Nonpathogen - hypothetical protein CAC1115 1 None None None 15894732 Common rbsB Ribose ABC transporter (ribose-binding periplasmic component) CAC1453 103 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15896786 Common natB Na+ ABC transporter, NATB CAC3550 19 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 15894278 Common - Putative intracellular protease CAC0991 148 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15896158 Common - Uncharacterized protein, YABG B.subtilis ortholog CAC2905 11 None None None 15895916 Common glnA Glutamine synthetase type III CAC2658 116 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 15896467 Common - Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) CAC3220 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895558 Common nprE Extracellular neutral metalloprotease, NPRE, fused to ChW-repeats CAC2290 49 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 15896229 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B CAC2976 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 15895189 Common - hypothetical protein CAC1915 1 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15895604 Common - Phosphomannomutase CAC2337 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15893917 Common - Predicted hydrolase of the HAD family CAC0629 150 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15895227 Nonpathogen - hypothetical protein CAC1954 3 None None None 15894824 Common deoA pyrimidine-nucleoside phosphorylase CAC1546 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 15894913 Common - Predicted nucleic acid binding protein, containing 2 S1 domains, YITL B.subtilis ortholog CAC1635 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 15893593 Common - Signal peptidase II (PSP1) homolog, YAAT B.subtilis ortholog CAC0301 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 15896160 Common - Glycosyltransferase CAC2907 168 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15893603 Common - PolyA polymerase CAC0311 174 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15896805 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase CAC3571 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 15894607 Common - hypothetical protein CAC1327 1 None None None 15894994 Common - hypothetical protein CAC1717 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 15896876 Common - Oligopeptide ABC transporter, permease component CAC3643 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15896887 Common - Heavy-metal binding protein (similar to N-terminal domain of MerA) CAC3654 31 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 15896740 Common - Nucleoside-diphosphate-sugar epimerase CAC3503 89 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15894283 Common - hypothetical protein CAC0996 1 None None None 15894296 Common - Cell wall biogenesis enzyme (N-terminal domain related to N-Acetylmuramoyl-L-alanine amidase and C-terminal domain related to L-alanoyl-D-glutamate peptidase); peptodoglycan-binding domain CAC1009 29 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 15896600 Nonpathogen - hypothetical protein CAC3357 1 None None None 15895890 Common - hypothetical protein CAC2632 3 None None None 15894139 Common - Amino acid permease CAC0852 117 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15896269 Common - Predicted xylanase/chitin deacetylase CAC3017 112 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15896298 Common - Uncharacterized membrane protein, putative virulence factor MviN CAC3047 190 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 15896531 Common - Chey-like receiver domain containing protein, YCBB B.subtilis ortholog CAC3286 10 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 15893576 Common - NAD-dependent deacetylase CAC0284 153 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 15893686 Common kdgK 2-keto-3-deoxygluconate kinase (gene kdgK) CAC0395 189 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15895357 Common - Stage III sporulation protein AG, SpoIIIAG CAC2087 15 None None None 15895424 Common - hypothetical protein CAC2155 16 None None None 15895577 Common - Methenyl tetrahydrofolate cyclohydrolase (serine cycle enzyme) CAC2310 34 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 15896240 Common - Uncharacterized conserved protein, YABE B.subtilis ortholog CAC2988 36 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 15894351 Nonpathogen - Uncharacterized protein, related stage III sporulation protein AH of Bacillus sp. CAC1065 2 None None None 15895932 Common - ATP-dependent superfamily I DNA helicase, PCRA CAC2674 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15896235 Common - hypothetical protein CAC2983 1 None None None 15896123 Common atpF FoF1-type ATP synthase B subunit CAC2869 145 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 15894178 Nonpathogen - hypothetical protein CAC0891 1 None None None 15896861 Common - PP-loop superfamily ATPase, confers aluminum resistance CAC3627 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 15894090 Nonpathogen - hypothetical protein CAC0803 2 None None None 15895332 Common - TRNA nucleotidyltransferase family enzyme CAC2062 199 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15896411 Common parB anthranilate synthase component I CAC3163 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15895525 Nonpathogen - hypothetical protein CAC2257 1 None None None 15894484 Nonpathogen - hypothetical protein CAC1201 1 None None None 15895940 Nonpathogen - hypothetical protein CAC2682 2 None None None 15896479 Common - 2-phosphosulfolactate phosphatase CAC3233 47 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 15895279 Common mmgB 3-Hydroxyacyl-CoA dehydrogenase CAC2009 159 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 15894322 Nonpathogen - hypothetical protein CAC1035 1 None None None 15895439 Nonpathogen - Predicted membrane protein CAC2170 2 None None None 15893581 Common - Response regulator (CheY domain, HTH domain) CAC0289 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895132 Common - Predicted metal-dependent peptidase CAC1857 17 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 15895247 Nonpathogen - Hypothetical secreted protein CAC1976 1 None None None 15896538 Common - hypothetical protein CAC3293 4 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 15893622 Common - prolipoprotein diacylglyceryl transferase CAC0330 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 15894717 Nonpathogen - hypothetical protein CAC1438 1 None None None 15895801 Common - Predicted acetyltransferase CAC2539 41 COG0456 RimI, Acetyltransferases General function prediction only 15894857 Common - Methyl-accepting chemotaxis-like protein (chemotaxis sensory transducer) CAC1579 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15895946 Common - Alpha/beta superfamily hydrolase (possible chloroperoxidase) CAC2688 153 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15895981 Nonpathogen - hypothetical protein CAC2724 1 None None None 15894924 Common - hypothetical protein CAC1647 3 None None None 15895619 Common - hypothetical protein CAC2352 3 None None None 15896447 Common - pantothenate kinase CAC3200 128 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 15896043 Common - Xaa-Pro aminopeptidase family enzyme CAC2788 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15895677 Common - Zn-dependent protease of MPP family CAC2411 196 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 15896726 Common - hypothetical protein CAC3489 8 None None None 15895096 Common - Phosphocarrier Protein (Hpr) CAC1820 106 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 15895223 Common - hypothetical protein CAC1950 9 COG3655 COG3655, Predicted transcriptional regulator Transcription 15895004 Common - Protein serine/threonine phosphatase, PP2C family (YLOO B.subtilis ortholog) CAC1727 131 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 15896890 Common - NADP-dependent glyceraldehyde-3-phosphate dehydrogenase CAC3657 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15894222 Common hisZ ATP phosphoribosyltransferase regulatory subunit CAC0935 247 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 15894726 Common - MDR-type permease, probably tetracycline resistance protein CAC1447 48 None None None 15894072 Nonpathogen - hypothetical protein CAC0785 2 None None None 15894518 Common thrB Homoserine kinase (thrB) CAC1235 122 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 15894311 Common nadB L-aspartate oxidase CAC1024 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 15895520 Common - Alpha-glucosidase fused to unknown alpha-amylase C-terminal. domain CAC2252 88 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 15893481 Common nagA N-acetylglucosamine-6-phosphate deacetylase (gene nagA) CAC0188 120 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 15896965 Common trmE tRNA modification GTPase TrmE CAC3734 222 COG0486 ThdF, Predicted GTPase General function prediction only 15894966 Common sigK sporulation sigma factor SigK CAC1689 212 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15894307 Common - hypothetical protein CAC1020 1 None None None 15895115 Common - Predicted acetyltransferase domain containing protein CAC1840 7 COG0456 RimI, Acetyltransferases General function prediction only 15894817 Common - Gamma-glutamylcysteine synthetase CAC1539 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 15895963 Common - Uncharacterized conserved membrane protein, DedA family CAC2706 97 COG0398 COG0398, Uncharacterized conserved protein Function unknown 15893822 Common - PTS system, arbutin-like IIBC component CAC0532 55 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15896163 Common - Spore coat protein cotS related CAC2910 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 15895312 Common - ABC transported MDR-type, permease component CAC2042 3 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 15895656 Common argC N-acetyl-gamma-glutamyl-phosphate reductase CAC2390 215 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 15895293 Nonpathogen - Membrane protein, related to copy number protein COP from Clostridium perfringens plasmid pIP404 (GI:116928) CAC2023 1 None None None 15894530 Common pbpA Penicillin-binding protein 2 CAC1247 194 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15893886 Common gerKB Spore germination protein, gerKB CAC0597 13 None None None 15896763 Common - FMN-binding protein CAC3526 8 None None None 15893407 Common - Glutamine-binding periplasmic protein fused to glutamine permease CAC0111 180 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15894211 Nonpathogen - Predicted membrane protein CAC0924 1 None None None 15893951 Nonpathogen - hypothetical protein CAC0663 1 None None None 15896516 Common - Transcriptional regulator, AcrR family CAC3271 132 COG1309 AcrR, Transcriptional regulator Transcription 15896374 Common rpsQ 30S ribosomal protein S17 CAC3124 223 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 15895871 Common glcK Transcriptional regulators of NagC/XylR family CAC2613 139 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15896738 Common - Predicted phosphosugar isomerase CAC3501 58 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 15895266 Common - hypothetical protein CAC1996 4 None None None 15895773 Common - Nitroreductase family protein CAC2508 56 COG0778 NfnB, Nitroreductase Energy production and conversion 15894559 Nonpathogen - Predicted membrane protein CAC1277 1 None None None 15894729 Common - Predicted alpha/beta superfamily hydrolase CAC1450 4 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15896854 Common - Amino acid (probably glutamine) ABC transporter, periplasmic binding protein component CAC3620 190 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15895861 Common - spermidine synthase CAC2602 131 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 15896045 Nonpathogen - hypothetical protein CAC2790 1 None None None 15895067 Common - Undecaprenyl pyrophosphate synthase CAC1791 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15895267 Common - Predicted glycosyltransferase CAC1997 30 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 15895361 Common - Stage III sporulation protein AC, SpoIIIAC CAC2091 7 None None None 15894468 Common - hypothetical protein CAC1185 4 None None None 15893785 Common - PemK family of DNA-binding proteins CAC0494 61 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 15894424 Nonpathogen - hypothetical protein CAC1140 1 None None None 15894193 Common - Alanyl-tRNA synthetase related protein CAC0906 245 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 15894788 Common - hypothetical protein CAC1510 1 None None None 15895060 Common smf DNA uptake protein CAC1784 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 15895509 Common - Cation transport P-type ATPase CAC2241 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15893697 Nonpathogen - Predicted membrane protein, containing FHA domain CAC0406 4 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 15894618 Common araE Possible sugar-proton symporter CAC1339 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15895635 Common - hypothetical protein CAC2368 2 None None None 15896640 Common - Predicted transcriptional regulator CAC3399 27 COG1733 COG1733, Predicted transcriptional regulators Transcription 15894421 Nonpathogen - hypothetical protein CAC1137 1 None None None 15896547 Common - Superfamily II DNA/RNA helicases, SNF2 family CAC3303 145 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 15896324 Common - Sugar transferase involved in lipopolysaccharide synthesis CAC3073 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 15894658 Common cobI/cbiL cobalt-precorrin-2 C(20)-methyltransferase CAC1379 175 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 15895135 Common - hypothetical protein CAC1860 14 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 15896950 Common - Uncharacterized predicted membrane protein, YYBS B.subtilis homolog CAC3719 6 COG4241 COG4241, Predicted membrane protein Function unknown 15894911 Common - Protein from bacterioferritin family CAC1633 10 COG1633 COG1633, Uncharacterized conserved protein Function unknown 15894973 Common sigG sporulation sigma factor SigG CAC1696 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15894209 Nonpathogen - Uncharacterized small conserved protein, homolog of yfjA/yukE B.subtilis CAC0922 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15896015 Common - Response regulator (CheY receiver domain and HTH-type DNA-binding domain) CAC2759 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15893475 Common - Beta-glucosidase homolog CAC0182 183 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 15893375 Nonpathogen - hypothetical protein CAC0079 1 None None None 15895343 Common recN DNA repair protein recN, ATPase CAC2073 212 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 15895397 Common murF UDP-N-acetylmuramyl pentapeptide synthase CAC2128 212 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 15896525 Common - Possible surface protein, responsible for cell interaction; contains cell adhesion domain and ChW-repeats CAC3280 37 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15896141 Common tdk thymidine kinase CAC2887 91 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 15896000 Common - Predicted permease, YXIO B.subtilis ortholog CAC2743 70 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 15895123 Common cmk cytidylate kinase CAC1848 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 15895620 Nonpathogen - hypothetical protein CAC2353 1 None None None 15893965 Common - hypothetical protein CAC0677 100 COG0398 COG0398, Uncharacterized conserved protein Function unknown 15894738 Common - PTS system, fructose(mannose)-specific IIC CAC1459 28 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 15895253 Common - Predicted membrane protein CAC1982 6 None None None 15893493 Common - Uncharacterized membrane protein CAC0200 2 COG2717 COG2717, Predicted membrane protein Function unknown 15894370 Common - alpha-xylosidase YicI CAC1085 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 15893662 Common - Response regulator (CheY-like domain and HTH domain) CAC0371 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15896943 Nonpathogen - hypothetical protein CAC3712 2 None None None 15893995 Common rpoN RNA polymerase factor sigma-54 CAC0707 146 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 15896351 Common - Predicted permease (Cobalt permease subfamily) CAC3100 91 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15895989 Common - ABC transporter, ATPase component CAC2732 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15896187 Common - Predicted transcriptional regulator CAC2934 151 COG1733 COG1733, Predicted transcriptional regulators Transcription 15894668 Common - Protein containing ChW-repeats and cell-adhesion domain CAC1389 23 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15895142 Common - Transcriptional regulator (phage-related) (Xre family) CAC1867 3 COG1396 HipB, Predicted transcriptional regulators Transcription 15895685 Common - Methyl-accepting chemotaxis protein CAC2419 27 None None None 15895246 Nonpathogen - Hypothetical secreted protein CAC1975 1 None None None 15896281 Nonpathogen - hypothetical protein CAC3030 1 None None None 15896264 Common - ATPase component of ABC transporter, with duplicated ATPase domains CAC3012 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15896378 Common rplV 50S ribosomal protein L22 CAC3128 223 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 15893384 Common - methionine sulfoxide reductase A CAC0088 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15893566 Common ansB aspartate ammonia-lyase CAC0274 239 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 15894502 Nonpathogen - hypothetical protein CAC1219 1 None None None 15896389 Common rpsL 30S ribosomal protein S12 CAC3140 237 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 15894777 Common - Predicted flavoprotein CAC1498 13 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15896511 Nonpathogen - hypothetical protein CAC3266 3 COG5660 COG5660, Predicted integral membrane protein Function unknown 15896889 Common - Uncharacterized conserved protein, yaiN/yohL family CAC3656 91 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 15894458 Common - Hypothetical protein, CF-35 family CAC1175 1 None None None 15895927 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B CAC2669 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 15894701 Common - Uncharacterized CBS domain-containing protein, YUGS B.subtilis ortholog CAC1422 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15895917 Common - Putative stress-responsive transcriptional regulator PspC CAC2659 39 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 15896071 Common - Hypothetical protein, CF-17 family CAC2816 1 None None None 15896036 Nonpathogen - hypothetical protein CAC2781 1 None None None 15893985 Common - Galactose mutarotase related enzyme CAC0697 33 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 15895714 Common - Predicted flavoprotein CAC2449 79 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15895043 Common - RNA polymerase factor sigma-70 CAC1766 8 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 15893816 Common - ABC transporter, ATPase component CAC0526 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15894508 Nonpathogen - hypothetical protein CAC1225 1 None None None 15894721 Common - hypothetical protein CAC1442 3 None None None 15893791 Common - Membrane protein containing C-terminal PDZ domain CAC0500 12 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15895643 Common oppA Oligopeptide ABC-type transporter, periplasmic binding component (Frameshift) CAC2377 114 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15895149 Nonpathogen - hypothetical protein CAC1874 1 None None None 15893780 Common acpS 4'-phosphopantetheinyl transferase CAC0489 170 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 15893648 Common - Permease of the Na:galactoside symporter family CAC0357 65 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15895920 Nonpathogen - hypothetical protein CAC2662 1 None None None 15894375 Common - 5-formyltetrahydrofolate cyclo-ligase CAC1090 99 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 15893522 Common - Inactivated predicted Zn-dependent protease, PMBA ortholog CAC0230 39 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15896129 Common tagO Undecaprenyl-phosphate CAC2875 223 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15894145 Common - Phosphinothricin acetyltransferase CAC0858 116 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 15895370 Nonpathogen - hypothetical protein CAC2100 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 15896882 Common spoVT Possible stage V sporulation protein T, transcriptional regulator AbrB homolog CAC3649 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 15894697 Common - Nitroreductase family protein CAC1418 177 COG0778 NfnB, Nitroreductase Energy production and conversion 15894866 Common - Malolactic regulator, LysR family CAC1588 188 COG0583 LysR, Transcriptional regulator Transcription 15896205 Common gatY tagatose-bisphosphate aldolase CAC2952 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15893539 Nonpathogen - Predicted permease CAC0247 1 None None None 15894031 Common - Na+/H+ antiporter, ortholog YQKI B.subtilis CAC0744 54 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 15895883 Nonpathogen - Predicted membrane protein CAC2625 1 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 15894049 Common - Permease, probably tetracycline resistance protein CAC0762 98 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15895112 Common mutS DNA mismatch repair protein CAC1837 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15896216 Common lacG 6-Phospho-Beta-D-Galactosidase CAC2963 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15895406 Common - Cation transport P-type ATPase CAC2137 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 15895954 Common - Predicted membrane protein CAC2696 2 None None None 15894798 Common - hypothetical protein CAC1520 3 None None None 15893588 Common csfB Zn-finger containing protein, csfB B.subtilis homolog CAC0296 2 None None None 15896832 Common - Rubrerythrin CAC3598 28 COG1592 COG1592, Rubrerythrin Energy production and conversion 15894800 Common - Small acid-soluble spore protein CAC1522 1 None None None 15893469 Common appA Oligopeptide-binding protein, periplasmic component CAC0176 216 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15895851 Nonpathogen - Hypothetical protein, CF-41 family CAC2591 2 None None None 15896343 Common 231 amidase, germination specific (cwlC/cwlD B.subtilis ortholog) CAC3092 135 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15895212 Nonpathogen - hypothetical protein CAC1939 1 None None None 15894349 Common - TPR-repeat-containing protein CAC1063 61 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15894575 Common - hypothetical protein CAC1293 144 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 15896754 Common - Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) CAC3517 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15896273 Common - Possible phosphoglycerate mutase CAC3021 192 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 15896674 Common - Transcriptional regulators, AcrR family CAC3433 25 COG1309 AcrR, Transcriptional regulator Transcription 15896134 Common - ribose-5-phosphate isomerase B CAC2880 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 15893434 Common - Predicted permease CAC0139 9 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15894705 Common - Possible transcriptional regulator from leucine-rich protein (LRPR) family CAC1426 50 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 15895104 Common - TldD protein fragment CAC1828 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15895363 Common - Stage III sporulation protein AA, SpoIIIAA CAC2093 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 15896624 Common - hypothetical protein CAC3383 118 COG1690 RtcB, Uncharacterized conserved protein Function unknown 15894952 Common - Predicted transcriptional regulator (HTH winged helix type) CAC1675 177 COG1959 COG1959, Predicted transcriptional regulator Transcription 15894024 Common - glutamate dehydrogenase CAC0737 165 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 15894623 Common xylB Sugar kinase, possible xylulose kinase CAC1344 64 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15896905 Common xylR XylR transcriptional regulator CAC3673 161 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15894918 Common - Uncharacterized protein, YQCG B.subtilis homolog; CF-7 family CAC1640 5 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15894492 Common nrdD anaerobic ribonucleoside triphosphate reductase CAC1209 106 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 15896308 Common - Glycosyltransferase CAC3057 99 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15895499 Common murG N-acetylglucosaminyl transferase CAC2231 209 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15894167 Common - Periplasmic amino acid binding protein CAC0880 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15896319 Common - Glycosyltransferase CAC3068 20 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15894340 Common - LPS glycosyltransferase CAC1053 231 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15896576 Common - Uncharacterized conserved protein, related to pyruvate formate-lyase activating enzyme CAC3333 20 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 15893442 Common - ABC transporter, ATP-binding protein CAC0147 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15894042 Common - Multimeric flavodoxin WrbA family protein, diverged or disrupted CAC0755 4 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15894242 Common - ATP-dependent Zn protease CAC0955 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15893860 Common - PTS enzyme II, ABC component CAC0570 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15895834 Common - Predicted S-adenosylmethionine-dependent methyltransferase CAC2574 31 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15896357 Common rpsK 30S ribosomal protein S11 CAC3106 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 15894385 Common - Secreted protein, similar to catalytic domain of murein transglycosylase CAC1100 167 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15896565 Common - Predicted acetyltransferase CAC3322 6 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15895858 Nonpathogen - hypothetical protein CAC2599 1 None None None 15893396 Common hemB delta-aminolevulinic acid dehydratase CAC0100 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 15894807 Common - Beta-xylosidase, family 43 glycosyl hydrolase CAC1529 22 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 15895720 Nonpathogen - Hypothetical protein, CF-13 family CAC2455 1 None None None 15894471 Nonpathogen - hypothetical protein CAC1188 1 None None None 15893358 Common - Phage-related protein, gp16 CAC0061 20 COG5412 COG5412, Phage-related protein Function unknown 15895137 Common - hypothetical protein CAC1862 2 None None None 15894137 Common - Nitroreductase family protein CAC0850 99 COG0778 NfnB, Nitroreductase Energy production and conversion 15893327 Common - Distantly related to cell wall-associated hydrolase, similar to yycO Bacillus subtilis CAC0029 3 COG3863 COG3863, Uncharacterized distant relative of cell wall-associated hydrolases Function unknown 15896701 Common - hypothetical protein CAC3461 42 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15893630 Common - Mono-ADP-ribosyltransferase C3 precursor; CF-7 family CAC0338 9 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15895433 Common flgC flagellar basal body rod protein FlgC CAC2164 124 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 15895613 Common - Glycosyltransferase CAC2346 125 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15895639 Common sspA Small acid-soluble spore protein CAC2372 7 None None None 15895960 Common groEL chaperonin GroEL CAC2703 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15896703 Common - Uncharacterized conserved protein (fragment) CAC3464 9 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 15894773 Common - Hypothetical protein, CF-32 family CAC1494 11 None None None 15895787 Common - Glycosyltransferase CAC2523 174 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894550 Common comEA Competence ComEA protein CAC1268 39 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 15895477 Common csrA Carbon storage regulator, csrA CAC2209 85 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 15895465 Common - Aminoglycoside N3'-acetyltransferase CAC2197 9 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 15894633 Common - Phosphotransferase system IIA component CAC1354 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 15893659 Common - 4-aminobutyrate aminotransferase CAC0368 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 15893517 Common - Sensory transduction histidine kinase CAC0225 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15896055 Common - CotJC-like protein (GS80 family) CAC2800 47 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 15894208 Common - Metal-dependent amidohydrolase CAC0921 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 15896969 Common rnpA ribonuclease P CAC3738 12 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 15895089 Common - Predicted Fe-S oxidoreductase CAC1813 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15894896 Nonpathogen - hypothetical protein CAC1618 1 None None None 15896521 Common nrdF ribonucleotide-diphosphate reductase subunit beta CAC3276 162 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 15895722 Nonpathogen - hypothetical protein CAC2457 1 None None None 15896018 Common - Polyferredoxin CAC2762 81 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 15893707 Common - TPR-repeat-containing protein CAC0416 134 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15894188 Common - O-sialoglycoprotein endopeptidase CAC0901 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 15896771 Common - Type II restriction enzyme, methylase subunit CAC3535 68 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15894685 Common - Transcriptional antiterminator (BglG family) CAC1406 29 COG3711 BglG, Transcriptional antiterminator Transcription 15893548 Common nifD Nitrogenase molybdenum-iron protein, alpha chain (nitrogenase component I) gene nifD CAC0256 61 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15893788 Common ftsE Cell division ATP-binding protein CAC0497 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 15896912 Common kdpC/atkC K+-transporting ATPase, c chain CAC3680 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 15894257 Common - Isopropylmalate synthase CAC0970 191 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15895703 Common - Predicted phosphatase CAC2438 22 None None None 15894328 Common argS arginyl-tRNA synthetase CAC1041 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15895502 Common nifS NifS family enzyme (cysteine desulfurase/cysteine sulfinate desulfinase) CAC2234 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 15896750 Nonpathogen - hypothetical protein CAC3513 4 None None None 15895906 Common - hypothetical protein CAC2648 9 COG5523 COG5523, Predicted integral membrane protein Function unknown 15893318 Common - MDR-type permease CAC0020 197 COG1511 COG1511, Predicted membrane protein Function unknown 15896059 Common - Predicted Zn-dependent hydrolase from metallo-beta-lactamase superfamily CAC2804 52 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15895386 Common pfs 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase CAC2117 102 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15893749 Common - Permease CAC0458 147 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15894158 Common - hypothetical protein CAC0871 3 None None None 15894584 Common - Predicted SAM-dependent methyltransferase CAC1302 36 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 15894556 Common rpsT 30S ribosomal protein S20 CAC1274 118 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 15896490 Common - Subtilisin like protease (two fused domains) CAC3245 53 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 15895950 Common - O-Acetyltransferase, from isoleucine patch superfamily CAC2692 79 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15896767 Nonpathogen - hypothetical protein CAC3530 1 None None None 15896293 Common - O-actetyl transferase related protein CAC3042 23 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 15893768 Common - AP superfamily CAC0477 31 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 15893892 Common - Superfamily I DNA and RNA helicase CAC0603 55 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 15896852 Common - ABC-type polar amino acid transport system, ATPase component CAC3618 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15894483 Common - Similar to phospho-adenylylsulfate sulfotransferase CAC1200 29 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15893856 Common - Malate dehydrogenase CAC0566 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 15895191 Nonpathogen - hypothetical protein CAC1917 1 None None None 15893426 Common - Uncharacterized membrane protein, YTAF B.subtilis ortholog CAC0130 15 COG1971 COG1971, Predicted membrane protein Function unknown 15893550 Common nifE Nitrogenase iron-molibdenum cofactor biosinthesis protein, gene nifE CAC0258 60 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15894803 Common - Uncharacterized protein, homolog of PHNB E.coli CAC1525 58 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 15893455 Common - Predicted acetyltransferase CAC0160 6 COG3393 COG3393, Predicted acetyltransferase General function prediction only 15895097 Common purB adenylosuccinate lyase CAC1821 189 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 15894445 Nonpathogen - Hypothetical protein, CF-11 family CAC1162 1 None None None 15896825 Common - Acyl-ACP thioesterase CAC3591 24 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 15894265 Common - Possible elongation subunit of DNA-dependent DNA polymerase CAC0978 32 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 15895533 Common - hypothetical protein CAC2265 56 COG2966 COG2966, Uncharacterized conserved protein Function unknown 15893491 Common - Uncharacterized membrane protein, ortholog YYAS B.subtilis CAC0198 16 COG2364 COG2364, Predicted membrane protein Function unknown 15894943 Common - Predicted membrane protein CAC1666 12 COG4905 COG4905, Predicted membrane protein Function unknown 15894273 Common - Lipoprotein, attached to the cytoplasmic membrane, NLPA family CAC0986 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 15894544 Common nadD nicotinic acid mononucleotide adenyltransferase CAC1262 189 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 15895756 Common - Predicted acetyltransferase CAC2491 10 COG3393 COG3393, Predicted acetyltransferase General function prediction only 15894827 Common bsaA Glutathione peroxidase CAC1549 115 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 15895169 Common - Phage terminase-like protein, large subunit CAC1895 47 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 15893502 Common - Predicted membrane protein; CF-20 family CAC0209 1 None None None 15894767 Common - Glycosyltransferase involved in cell wall biogenesis CAC1488 91 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894105 Common - Diguanylate cyclase/phosphodiesterase domain (GGDEF) containing protein CAC0818 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15895744 Nonpathogen - hypothetical protein CAC2479 1 None None None 15894014 Common yifK Amino acid permease, gene yifK CAC0727 133 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15896844 Common - ABC-type MDR transport system, permease component CAC3610 9 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15896970 Common rpmH 50S ribosomal protein L34 CAC3739 1 None None None 15896097 Common - Transcription accessory protein TEX, RNA-binding protein containing S1 domain CAC2842 226 COG2183 Tex, Transcriptional accessory protein Transcription 15896896 Common - Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) CAC3663 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895408 Common flgG flagellar basal body rod protein FlgG CAC2139 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15896095 Common - Predicted acetyltransferase CAC2840 199 COG0456 RimI, Acetyltransferases General function prediction only 15893505 Common - Biotin-(acetyl-CoA carboxylase) ligase CAC0212 197 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 15893972 Common - CBS domains CAC0684 185 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 15894060 Common - ABC-type cobalt transport protein ATPase component CAC0773 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15893300 Common dnaN DNA polymerase III subunit beta CAC0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 15895978 Common - Response regulator (CheY-like reciever domain and HTH-type DNA-binding domain) CAC2721 217 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 15896364 Common rplO 50S ribosomal protein L15 CAC3114 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 15895762 Nonpathogen - Hypothetical secreted protein CAC2497 1 None None None 15894476 Nonpathogen - hypothetical protein CAC1193 1 None None None 15896744 Common - Transcriptional regulator, MerR family CAC3507 126 COG0789 SoxR, Predicted transcriptional regulators Transcription 15896528 Common - Transcriptional regulator, MarR/EmrR family CAC3283 68 COG1846 MarR, Transcriptional regulators Transcription 15895881 Common - Possible sensorory transduction protein, containing AAA ATPase domain, TPR repeats domain, GGDEF domain and GAF domain CAC2623 183 COG3899 COG3899, Predicted ATPase General function prediction only 15894434 Nonpathogen - hypothetical protein CAC1151 1 None None None 15896066 Nonpathogen - Hypothetical protein, CF-17 family CAC2811 1 None None None 15896251 Nonpathogen - hypothetical protein CAC2999 1 None None None 15896177 Common thiS Uncharacterized protein, possibly involved in thiamine biosynthesis CAC2924 18 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 15894345 Nonpathogen - Predicted membrane protein CAC1058 1 None None None 15896321 Common - Glycosyltransferase CAC3070 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15896693 Common xynD Beta-xylosidase, family 43 glycosyl hydrolase CAC3452 41 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 15896258 Common - Zn-dependent peptidase, insulinase family CAC3006 88 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 15896222 Common - 3-methyladenine DNA glycosylase CAC2969 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 15895368 Common - hypothetical protein CAC2098 1 None None None 15896631 Common - Response regulator (CheY-like receiver domain containing) CAC3390 145 COG3947 COG3947, Response regulator containing CheY-like receiver and SARP domains Signal transduction mechanisms 15895782 Common nrpE Extracellular neutral metalloprotease, NPRE CAC2517 46 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 15895310 Common - ABC transported MDR-type, ATPase component CAC2040 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15895318 Nonpathogen - Uncharacterized secreted protein CAC2048 3 None None None 15894534 Common - Possible membrane metalloendopeptidase CAC1252 165 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15895730 Nonpathogen - hypothetical protein CAC2465 1 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 15895999 Common - Predicted membrane protein CAC2742 1 None None None 15894520 Common - hypothetical protein CAC1237 1 None None None 15894712 Nonpathogen - hypothetical protein CAC1433 1 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15895938 Common pgi glucose-6-phosphate isomerase CAC2680 181 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 15896385 Nonpathogen - Uncharacterized C4-type Zn-finger containing protein CAC3135 1 None None None 15896197 Common - N-terminal domain intergin-like repeats and c-terminal- cell wall-associated hydrolase domain CAC2944 158 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15894568 Common - Fe-S oxidoreductase CAC1286 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15894565 Common dnaJ Molecular chaperones DnaJ (HSP40 family) CAC1283 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15896858 Common - 6-pyruvoyl-tetrahydropterin synthase CAC3624 85 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15893849 Common - Transcriptional regulator, MarR/EmrR family CAC0559 24 COG1846 MarR, Transcriptional regulators Transcription 15894959 Common - Ferric uptake regulation protein CAC1682 209 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15895732 Nonpathogen - hypothetical protein CAC2467 4 COG5513 COG5513, Predicted secreted protein Function unknown 15893395 Common hemL glutamate-1-semialdehyde aminotransferase CAC0099 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 15896682 Common - DNA/RNA helicase, SNF2 CAC3441 138 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 15893654 Common - Deoxyinosine 3'endonuclease CAC0363 72 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 15893949 Common - ABC transporter ATP-binding protein (multidrug resistance protein) CAC0661 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15896465 Common - Periplasmic trypsin-like serine protease (with PDZ domain), HtrA subfamily CAC3218 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15895399 Common spoVD Stage V sporulation protein D, spoVD, FtsI/pbp family CAC2130 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15894403 Nonpathogen - Phage related protein CAC1118 1 None None None 15895307 Nonpathogen - Hypothetical protein, CF-39 family CAC2037 1 None None None 15896642 Nonpathogen - Predicted membrane protein CAC3401 1 None None None 15894935 Common - Phospholipase D family protein CAC1658 56 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15896330 Common - Uncharacterized conserved protein, YPPB B.subtilis ortholog CAC3079 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 15896872 Common - Oligopeptide ABC transporter, permease component CAC3638 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15896307 Common - Nucleoside-diphosphate-sugar pyrophosphorylase CAC3056 231 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 15894915 Nonpathogen - Hypothetical protein, CF-12 family CAC1637 1 None None None 15894393 Common - Lyc gene autolisin (1,4-bets-N-acetylmuramidase), family 25 of glycosyl hydrolase; peptodoglycan-binding domain CAC1108 37 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 15894339 Common - Membrane protease subunit, stomatin/prohibitin homolog CAC1052 221 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15895419 Common fliP flagellar biosynthesis protein FliP CAC2150 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 15895967 Common etfB Electron transfer flavoprotein beta-subunit CAC2710 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 15893794 Common uvrA Excinuclease ABC subunit A (ATP-ase), (uvrA) CAC0503 246 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 15894500 Common - Guanylate kinase (P-loop type) CAC1217 57 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 15896778 Common - hypothetical protein CAC3542 7 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 15894051 Common - putative oxidoreductase CAC0764 234 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 15894431 Nonpathogen - hypothetical protein CAC1148 1 None None None 15896085 Common - Acylphosphatase, ACYP CAC2830 76 COG1254 AcyP, Acylphosphatases Energy production and conversion 15893778 Common - Uncharacterized protein, ortholog of Thermotoga maritima (4981823) CAC0487 14 None None None 15894248 Common - Cobyric acid synthase CobQ CAC0961 52 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 15896150 Common - Predicted UDP-glucuronosyltransferase, YPFP B/subtilis ortholog CAC2897 45 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15893608 Common argF/I Ornithine carbomoyltransferase CAC0316 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 15893781 Common - Predicted sugar kinase, N-terminal region - uncharacterized conserved protein CAC0490 223 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 15896037 Common - Predicted permease CAC2782 68 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15895487 Common cheC Chemotaxis protein CheC CAC2219 34 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 15896184 Common - hypothetical protein CAC2931 17 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15894841 Common - Endoglucanase (fragment) CAC1563 3 None None None 15895829 Common - NimC/NimA family protein CAC2569 11 COG5015 COG5015, Uncharacterized conserved protein Function unknown 15893907 Common - Nitrate ABC transporter ATP binding protein CAC0619 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 15894372 Nonpathogen - hypothetical protein CAC1087 1 None None None 15893542 Common - Methyl-accepting chemotaxis protein CAC0250 126 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893410 Nonpathogen - Predicted membrane protein CAC0114 7 None None None 15895699 Common - Membrane associatehistidine kinase with HAMP domain CAC2434 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893337 Common - DNA segregation ATPase FtsK/SpoIIIE family protein, contains FHA domain CAC0039 201 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15896353 Common - ABC-type transporter, ATPase component (cobalt transporters subfamily) CAC3102 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15893712 Common - Uncharacterized membrane protein CAC0421 5 None None None 15895686 Common - Methyl-accepting chemotaxis protein CAC2420 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894744 Common - Transcriptional regulator, MarR/EmrR family CAC1465 36 COG1846 MarR, Transcriptional regulators Transcription 15895236 Common rpsA Ribosomal protein S1 CAC1964 180 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 15896291 Common - CPSC/CAPB subfamily ATPase CAC3040 197 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15895527 Common - Predicted transcriptional regulator of MarR-family CAC2259 13 None None None 15895221 Nonpathogen - hypothetical protein CAC1948 1 None None None 15894654 Common cobB Cobyrinic acid a,c-diamide synthase CobB CAC1375 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 15893850 Common - Integral membrane protein similar to antibiotic resistance protein B.subtilis CAC0560 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15895250 Nonpathogen - Predicted membrane protein CAC1979 2 None None None 15896080 Common - hypothetical protein CAC2825 92 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 15896407 Common trpF Phosphoribosylanthranilate isomerase CAC3159 197 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 15896926 Common - TPR-repeat-containing protein CAC3694 4 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15895084 Common pnpA polynucleotide phosphorylase/polyadenylase CAC1808 241 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 15894114 Common - Fructose-bisphosphate aldolase CAC0827 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15893837 Common - Lactoylglutation lyase CAC0547 9 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 15896660 Common - S-adenosylmethionine-dependent methyltransferase CAC3419 205 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15893940 Common - Uncharacterized conserved membrane protein, similar to MDR (VANZ) ORF of Enterococcus CAC0652 14 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 15894595 Nonpathogen - Peptodoglycan-binding domain containing protein CAC1315 2 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 15895196 Nonpathogen - hypothetical protein CAC1922 1 None None None 15895184 Nonpathogen - Predicted membrane protein CAC1910 1 None None None 15895593 Common - Diverged glycosyltransferase domain containing protein CAC2326 9 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15895092 Common - hypothetical protein CAC1816 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 15894881 Common - Diverged enzyme related to 2'-5' RNA ligase, ortholog YJCG B.subtilis CAC1603 8 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 15896589 Common - MDR-type permease CAC3346 181 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15895625 Common - RRNA methylase, YSGA B.subtilis ortholog CAC2358 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15895039 Common rnhB ribonuclease HII CAC1762 224 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 15895583 Common - Polysaccharide deacetylase-like protein; Xylanase/chitin deacetylase family enzyme CAC2316 105 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15896497 Common proC pyrroline-5-carboxylate reductase CAC3252 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 15893367 Nonpathogen - hypothetical protein CAC0070 1 None None None 15894313 Common - Superfamily I DNA helicase CAC1026 134 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 15894906 Common gyrA DNA topoisomerase IV subunit A CAC1628 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15895513 Common - Stress-induced protein OsmC CAC2245 31 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15893974 Common - Spore cortex-lytic enzyme prepeptide; peptodoglycan-binding domain CAC0686 46 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 15893463 Common - ABC transporter (ATP-binding protein) CAC0169 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15894074 Common - Uncharacterized conserved protein, repeats CAC0787 17 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 15895555 Common - Acyl-CoA reductase LuxC CAC2287 15 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15895965 Common hbd 3-hydroxybutyryl-CoA dehydrogenase CAC2708 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 15896690 Common - TPR-repeat-containing protein CAC3449 102 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15894224 Common hisD Histidinol dehydrogenase CAC0937 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 15896271 Common - Sensory transduction protein with GGDEF and EAL domains CAC3019 170 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15895338 Common - Sporulation factor spoIIM, uncharacterized membrane protein CAC2068 14 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 15894443 Nonpathogen - hypothetical protein CAC1160 1 None None None 15893888 Common - Transcriptional regulator, GntR family CAC0599 76 COG1725 COG1725, Predicted transcriptional regulators Transcription 15893800 Common - putative hydrolase CAC0509 84 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 15896717 Common - hypothetical protein CAC3480 1 None None None 15893752 Common - Mercuric resistance operon regulatory protein, MerR family CAC0461 126 COG0789 SoxR, Predicted transcriptional regulators Transcription 15894945 Common - Transcriptional regulator, AcrR family CAC1668 57 COG1309 AcrR, Transcriptional regulator Transcription 15895891 Common - Uncharaterized conserved protein, YOME B.subtilis ortholog CAC2633 22 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 15896765 Nonpathogen - hypothetical protein CAC3528 2 None None None 15895690 Common - Predicted phosphoesterase CAC2424 96 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 15896024 Common ppiB Peptidyl-prolyl cis-transisomerase, cyclophilin family CAC2769 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 15895071 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase CAC1795 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 15896247 Common - PTS system (Glucose-specific) component IIA CAC2995 59 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 15895716 Common - SoxR family transcriptional regulator fused to SAM-dependent methyltransferase CAC2451 56 COG0789 SoxR, Predicted transcriptional regulators Transcription 15893824 Common pps phosphoenolpyruvate synthase CAC0534 166 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15893610 Common - Membrane permease, predicted cation efflux pumps CAC0318 174 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15895210 Nonpathogen - hypothetical protein CAC1937 1 None None None 15894964 Common - Collagenase family protease CAC1687 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15895113 Common - Predicted Fe-S oxidoreductase, YMCB B.subtilis ortholog CAC1838 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15896815 Common - HAD superfamily hydrolase CAC3581 71 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15896390 Common - Ribosomal protein HS6-type CAC3141 15 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 15895863 Common - Transcriptional regulator (TetR/AcrR family) CAC2605 53 COG1309 AcrR, Transcriptional regulator Transcription 15895346 Common - Predicted rRNA methylase, YQXC B.subtilis ortholog CAC2076 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 15895304 Nonpathogen - hypothetical protein CAC2034 1 None None None 15893743 Nonpathogen - Permease CAC0452 7 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 15894605 Common - Uncharacterized conserved protein, YitT (B.subtilis) family CAC1325 47 COG1284 COG1284, Uncharacterized conserved protein Function unknown 15895065 Common pyrH uridylate kinase CAC1789 242 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 15895711 Nonpathogen - hypothetical protein CAC2446 1 None None None 15894215 Nonpathogen - Uncharacterized small conserved protein, homolog of yfjA/yukE B.subtilis CAC0928 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15896952 Nonpathogen - Hypothetical secreted protein CAC3721 2 None None None 15895543 Common apt adenine phosphoribosyltransferase CAC2275 187 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15893340 Nonpathogen - Hypothetical protein, CF-1 family CAC0042 1 None None None 15896626 Nonpathogen - hypothetical protein CAC3385 2 COG2378 COG2378, Predicted transcriptional regulator Transcription 15893831 Common - SAM-dependent methyltransferase CAC0541 52 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15894577 Common era GTP-binding protein Era CAC1295 237 COG1159 Era, GTPase General function prediction only 15894396 Nonpathogen - Hypothetical protein, CF-10 family CAC1111 1 None None None 15894791 Common asrA Anaerobic sulfite reductase (Fe-S subunit) CAC1513 31 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 15894171 Common - CAMP-binding domain (catabolite gene activator) and regulatory subunit of cAMP-dependent protein kinase CAC0884 68 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15893477 Nonpathogen - Predicted acetyltransferase CAC0184 5 COG3153 COG3153, Predicted acetyltransferase General function prediction only 15895947 Common - Uncharacterized protein, YJCM B.subtilis ortholog CAC2689 12 None None None 15893810 Common pyrC dihydroorotase CAC0519 213 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 15895581 Common - Membrane protein involved in the export of O-antigen and teichoic acid, RfbX family CAC2314 53 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15894281 Common - Predicted membrane protein CAC0994 1 None None None 15893373 Common - Conserved membrane protein, possible homolog of CAAX-like membrane endopeptidase CAC0077 3 None None None 15895483 Common fliY flagellar motor switch protein CAC2215 127 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 15896081 Common - Intracellular protease/amidase related enzyme (ThiJ family) CAC2826 119 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15896317 Common - Glycosyltransferase CAC3066 54 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15896455 Common - Uncharacterized protein, YABQ B.subtilis CAC3208 6 None None None 15894921 Common - Hypothetical protein, CF-7 family CAC1644 3 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15895846 Nonpathogen - Predicted membrane protein CAC2586 1 None None None 15896192 Common - Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) CAC2939 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15894826 Common trxB Thioredoxin reductase CAC1548 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15894611 Common uxuA mannonate dehydratase CAC1332 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 15894703 Common - Zn-dependent hydrolase, glyoxylase II family CAC1424 41 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15895658 Common - Uncharacterized ABC transporter, ATPase component CAC2392 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15893591 Common - Protein from nitrogen regulatory protein P-II (GLNB) family, ortholog YAAQ B.subtilis CAC0299 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 15895596 Common - Polysaccharide ABC transporter, permease component CAC2329 103 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15896602 Common - Nitroreductase family protein fused to ferredoxin domain CAC3359 51 COG0778 NfnB, Nitroreductase Energy production and conversion 15895629 Common thrS threonyl-tRNA synthetase CAC2362 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15894165 Common - Amino acid ABC transporter permease component CAC0878 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15895320 Nonpathogen - Predicted membrane protein CAC2050 1 None None None 15896536 Common - Selenocysteine lyase, NifS family CAC3291 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15896569 Common - Amino acid ABC-type transporter, permease component CAC3326 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15896562 Common - Signal transduction histidine kinase CAC3319 220 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 15896154 Common - Predicted membrane protein CAC2901 7 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15894457 Nonpathogen - hypothetical protein CAC1174 1 None None None 15896436 Common sms DNA repair protein RadA CAC3188 211 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 15893601 Common - Cell wall-associated hydrolase CAC0309 160 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 15893620 Common - Predicted metal-dependent hydrolase CAC0328 113 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 15894317 Common - FeoA-like protein, involved in iron transport CAC1030 13 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 15894855 Common - Ncharacterized conserved protein CAC1577 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 15893809 Common pykA Pyruvate kinase (pykA) CAC0518 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 15895491 Common cheD Chemotaxis protein CheD CAC2223 85 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 15895422 Common flbD Flagellar protein flbD CAC2153 28 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 15894868 Common - 2-oxoglutarate/malate translocator CAC1590 98 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15895602 Common - UTP-glucose-1-phosphate uridylyltransferase CAC2335 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15895345 Common - Predicted kinase CAC2075 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 15895078 Common infB translation initiation factor IF-2 CAC1802 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 15894416 Nonpathogen - hypothetical protein CAC1132 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15893960 Common - Fision threonyl-tRNA synthetase (N-terminal part) and uridine kinase CAC0672 137 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 15896369 Common rpsH 30S ribosomal protein S8 CAC3119 245 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 15893389 Common - Transcriptional regulators, LysR family CAC0093 192 COG0583 LysR, Transcriptional regulator Transcription 15893583 Common - bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein CAC0291 175 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 15894779 Nonpathogen - Predicted membrane protein CAC1500 1 None None None 15896211 Common - PTS system enzyme IIBC component (galactitol/fructose specific) CAC2958 20 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15894926 Common - hypothetical protein CAC1649 3 None None None 15894093 Common - hypothetical protein CAC0806 1 None None None 15896863 Common oppD Oligopeptide ABC transporter, ATPase component CAC3629 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15893881 Common ribA Riboflavin biosynthes protein RIBA (GTPcyclohydrolase/3,4-dihydroxy-2-butanone 4-phosphate synthase) CAC0592 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 15895002 Common - Predicted rRNA methylase, SUN family CAC1725 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 15896474 Nonpathogen - Predicted membrane protein CAC3228 1 None None None 15896242 Common csp Cold shock protein CAC2990 182 COG1278 CspC, Cold shock proteins Transcription 15893690 Common - Hypothetical protein, CF-24 family CAC0399 4 None None None 15893895 Common - C-terminal region cation efflux system protein CZCD CAC0606 206 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 15895152 Common - Hypothetical protein, CF-8 family CAC1877 2 None None None 15894641 Common bioA Adenosylmethionine-8-amino-7-oxononanoate aminotranferase CAC1362 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 15893990 Common - Predicted lipoprotein, Med/BMP family CAC0702 107 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 15895878 Common - HD-GYP hydrolase domain containing protein CAC2620 109 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15896195 Common - S-ribosylhomocysteinase CAC2942 54 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 15896485 Common - Predicted membrane protein CAC3240 1 None None None 15893401 Common - Ferredoxin CAC0105 25 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 15895919 Common ftsX Cell division protein FtsX CAC2661 79 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 15894127 Common potA Spermidine/putrescine ABC transporter, ATP-binding component CAC0840 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15896169 Common panD aspartate alpha-decarboxylase CAC2916 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 15896939 Nonpathogen - hypothetical protein CAC3708 1 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 15896885 Common alsS acetolactate synthase CAC3652 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15894423 Common - Phage related protein, YonO B.subtilis homolog CAC1139 2 None None None 15893409 Common - Transcriptional regulator of sugar metabolism CAC0113 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15896136 Common - Predicted translation factor (SUA5) CAC2882 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 15896752 Common - Alpha/beta superfamily hydrolase (possible peptidase) CAC3515 32 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 15894047 Common - Uncharacterized conserved protein, YTFE family, possibly metal-binding CAC0760 20 COG3945 COG3945, Uncharacterized conserved protein Function unknown 15895815 Common - Uncharacterized mebrane protein, YOAS B.subtilis ortholog CAC2553 10 None None None 15893352 Common - Uncharacterized predicted metal-binding protein, ortholog of Streptomyces (2808777) CAC0055 10 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 15895329 Common - Uncharacterized protein, YTFJ Bacillus subtilis ortholog CAC2059 21 COG3874 COG3874, Uncharacterized conserved protein Function unknown 15893935 Common - Predicted membrane protein CAC0647 2 None None None 15895015 Common kdtB Phosphopantetheine adenylyltransferase CAC1738 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 15896362 Common adk adenylate kinase CAC3112 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 15893448 Common - Beta-phosphoglucomutase, putative CAC0153 189 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15895206 Common dnaL hypothetical protein CAC1933 76 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 15894578 Common recO DNA repair protein RecO CAC1309 32 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15895956 Nonpathogen - hypothetical protein CAC2698 1 None None None 15894233 Common - ComE-like protein, Metallo beta-lactamase superfamily hydrolase, secreted CAC0946 127 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 15893989 Common - Uncharacterised protein, DegV family CAC0701 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 15895831 Common - Predicted acetyltransferase CAC2571 92 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15896341 Common - fumarate hydratase CAC3090 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 15895591 Common - Glycosyltransferase CAC2324 150 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15893301 Common - Small conserved protein, ortholog of YAAA B.subtilis CAC0003 49 COG2501 COG2501, Uncharacterized conserved protein Function unknown 15896907 Nonpathogen - Hypothetical secreted protein CAC3675 1 None None None 15896535 Common - Iron-regulated ABC-type transporter membrane component (SufB) CAC3290 180 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 15894872 Common rpsD 30S ribosomal protein S4 CAC1594 231 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15895942 Common - Sugar kinase, ribokinase family CAC2684 125 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15896672 Common - Membrane export protein, related to SecD/SecF protein exporters CAC3431 73 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 15894815 Common - hypothetical protein CAC1537 76 COG2013 COG2013, Uncharacterized conserved protein Function unknown 15896172 Common - hypothetical protein CAC2919 16 None None None 15893766 Common - HD-GYP domain CAC0475 125 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15894635 Common thiH thiamine biosynthesis protein ThiH CAC1356 57 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 15894085 Common - Phosphatidylserine synthase CAC0798 132 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 15894755 Common - Proline/glycine betaine ABC-type transport system, permease component CAC1476 165 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 15895661 Common - Predicted phosphatase, YWOA B.subtilis ortholog CAC2395 71 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15896179 Common sul Dihydropteroate synthase CAC2926 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 15893933 Common - Similar to spore germination protein CAC0645 9 None None None 15894040 Common - PolyA polymerase related protein (HD hydrolase) and P-loop ATP-ase domain CAC0753 17 COG4639 COG4639, Predicted kinase General function prediction only 15896592 Common - Transcriptional regulator, LysR family CAC3349 192 COG0583 LysR, Transcriptional regulator Transcription 15894802 Common - Methyl-accepting chemotaxis-like domain (chemotaxis sensory transducer) CAC1524 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893732 Common - Uncharacterized conserved membrane protein of SANA family CAC0441 75 COG1434 COG1434, Uncharacterized conserved protein Function unknown 15893460 Common - hypothetical protein CAC0166 15 COG1978 COG1978, Uncharacterized protein conserved in bacteria Function unknown 15894026 Common - Predicted membrane protein CAC0739 1 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 15895796 Common - Protein containing ChW-repeats CAC2533 7 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15895880 Common comE ComE-like protein, Metallo beta-lactamase superfamily hydrolase CAC2622 125 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 15895775 Nonpathogen - Predicted membrane protein CAC2510 1 None None None 15896838 Common ilvD Dihydroxyacid dehydratase CAC3604 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15893530 Common - ABC transporter, permease component CAC0238 7 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15894291 Nonpathogen - Predicted membrane protein CAC1004 1 None None None 15896591 Common mmuM homocysteine methyltransferase CAC3348 165 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 15894999 Common def peptide deformylase CAC1722 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 15895910 Common pyrF orotidine 5'-phosphate decarboxylase CAC2652 67 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 15895400 Common - hypothetical protein CAC2131 1 None None None 15894298 Common - Uncharacterized small membrane protein, homolog of ykvA B.subtilis CAC1011 25 COG3339 COG3339, Uncharacterized conserved protein Function unknown 15893827 Common - Acetylxylan esterase, acyl-CoA esterase or GDSL lipase family, strong similarity to C-terminal region of endoglucanase E precursor CAC0537 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 15894426 Common uvrD ATP-dependent DNA helicase, uvrD-like CAC1142 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15895470 Common - hypothetical protein CAC2202 17 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15896013 Nonpathogen - Predicted membrane protein CAC2757 1 None None None 15895055 Nonpathogen - hypothetical protein CAC1779 1 None None None 15896638 Common - Membrane associated methyl-accepting chemotaxis protein (with HAMP domain) CAC3397 156 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893629 Common - Hypothetical protein, CF-22 family CAC0337 2 None None None 15896611 Common - Predicted permease CAC3368 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896578 Common - Short-chain alcohol dehydrogenase family enzyme CAC3335 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 15895395 Common spoVE Stage V sporulation protein E, FtsW/MrdB/SpoVE family CAC2126 195 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15893314 Common - Related to HTH domain of SpoOJ/ParA/ParB/repB family, involved in chromosome partitioning CAC0016 48 COG4198 COG4198, Uncharacterized conserved protein Function unknown 15896830 Common pgsA Phosphatidylglycerophosphate synthase CAC3596 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15894781 Common - hypothetical protein CAC1502 6 None None None 15894463 Nonpathogen - Predicted membrane protein CAC1180 1 None None None 15895355 Common - Uncharacterized protein from alkaline shock protein family, YQHY B.subtilis ortholog CAC2085 41 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 15895809 Common - Possible membrane-associated methyl-accepting chemotaxis protein fused to HAMP domain CAC2547 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896286 Common - HAD superfamily hydrolase CAC3035 141 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15895125 Common - Transcriptional regulators, RpiR family CAC1850 85 COG1737 RpiR, Transcriptional regulators Transcription 15895887 Common - Hypothetical secreted protein CAC2629 2 None None None 15894473 Nonpathogen - Predicted Fe-S-cluster redox enzyme, YLON B.subtilis homolog CAC1190 4 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 15893660 Common - Predicted acetyltransferase CAC0369 11 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15893869 Common - hypothetical protein CAC0580 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 15896028 Common - Transcriptional regulators, AcrR family CAC2773 70 COG1309 AcrR, Transcriptional regulator Transcription 15895671 Common - Predicted glycosyltransferase CAC2405 112 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15895971 Common - ABC-type transporter, duplicate ATPase component CAC2714 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15896142 Common rpmE 50S ribosomal protein L31 CAC2888 179 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15895372 Common - Prepilin peptidase CAC2102 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 15894363 Common - Predicted phosphohydrolase, Icc family CAC1078 2 None None None 15894318 Common feoB FeoB-like GTPase, responsible for iron uptake CAC1031 194 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 15895240 Common - Possible plasmid transfer factor, TraK CAC1969 82 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 15893997 Common gapC Glyceraldehyde 3-phosphate dehydrogenase, gene gapC CAC0709 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15894723 Common - Uncharacterized conserved membrane protein, similar to MDR (VANZ) ORF of Enterococcus CAC1444 8 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 15893863 Common - Uncharacterized protein, homolog YvqG B.subtilis CAC0573 10 COG3595 COG3595, Uncharacterized conserved protein Function unknown 15896189 Common - Alpha/beta superfamily hydrolase CAC2936 30 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15894069 Common - hypothetical protein CAC0782 2 None None None 15893632 Nonpathogen - Predicted membrane protein CAC0341 1 None None None 15894571 Common - Uncharacterized conserved protein, YqeY B.subtilis ortholog CAC1289 154 COG1610 COG1610, Uncharacterized conserved protein Function unknown 15896283 Common - Galactose mutarotase related enzyme CAC3032 42 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 15896606 Nonpathogen - hypothetical protein CAC3363 1 None None None 15895100 Common clpA ATP-dependent Clp proteinase CAC1824 221 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15893725 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase CAC0434 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 15895251 Common - Predicted ATPase involved in pili biogenesis CAC1980 203 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 15896428 Common - Oligopeptide ABC transporter, permease component CAC3180 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15895259 Common - ABC-type iron (III) transport system, ATPase component CAC1989 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 15895121 Common motA flagellar motor protein MotA CAC1846 82 COG1291 MotA, Flagellar motor component Cell motility and secretion 15895041 Common - Predicted glutamine amidotransferase CAC1764 127 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 15893956 Common - Predicted membrane protein CAC0668 13 None None None 15893843 Common - Hypothetical protein, CF-8 family CAC0553 2 None None None 15896785 Common - Subtilisin-like serine protease CAC3549 39 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 15893684 Common kdgR KDG operon repressor (gene kdgR), LacI family CAC0393 128 COG1609 PurR, Transcriptional regulators Transcription 15894696 Nonpathogen - hypothetical protein CAC1417 1 None None None 15896233 Common - Mannose-1-phosphate guanyltransferase (pyrophosphorylase domain and phosphomannomutase domain) CAC2981 242 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 15896458 Common hbs DNA binding protein HU CAC3211 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15895450 Nonpathogen - hypothetical protein CAC2181 1 None None None 15893987 Common - Spore photoproduct lyase, splB CAC0699 26 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 15895025 Common rnc ribonuclease III CAC1748 215 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 15896807 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II CAC3573 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15894357 Common - Fe-S oxidoreductase CAC1072 58 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15895239 Nonpathogen - Pectate lyase related enzyme CAC1968 3 None None None 15895617 Common - Sugar transaminase, involved in dTDP-4-amino-4,6-dideoxyglucose biosynthesis CAC2350 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15896874 Common - Oligopeptide ABC transporter, ATPase component CAC3641 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 15895140 Common - Site-specific recombinases, DNA invertase Pin homolog CAC1865 125 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15895925 Common - Possible peptide ABC-type transporter, periplasmic binding component CAC2667 137 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15896034 Nonpathogen - hypothetical protein CAC2779 1 None None None 15894736 Common - PTS system, fructose(mannose)-specific IIA component CAC1457 33 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 15896262 Common - ATP-dependent RNA helicase (superfamily II), YDBR B.subtilis ortholog CAC3010 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15896527 Common - ABC-type multidrug/protein/lipid transport system, ATPase component CAC3282 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15894102 Common - Methyl-accepting chemotaxis protein CAC0815 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894836 Common - ABC-type transport system,membrane ATPase component CAC1558 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15893345 Nonpathogen - Uncharacterized small conserved protein, homolog of yfjA/yukE B.subtilis CAC0047 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15894377 Common - Predicted metal-dependent phosphoesterase (PHP family), YciV ortholog CAC1092 133 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 15895281 Common fabH Possible 3-oxoacyl-[acyl-carrier-protein] synthase III CAC2011 51 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 15896127 Common - acetyl-CoA acetyltransferase CAC2873 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 15893436 Common - Membrane permease, predicted cation efflux pumps CAC0141 12 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15894058 Common - cobalt transport protein CbiM CAC0771 83 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 15895330 Common scpB segregation and condensation protein B CAC2060 161 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 15893515 Common - Predicted N6-adenine-specific DNA methylase CAC0223 132 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 15896005 Common deaD ATP dependent RNA helicase DeaD, superfamily II CAC2748 242 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15893645 Common - Uncharacterized membrane protein CAC0354 10 COG5542 COG5542, Predicted integral membrane protein Function unknown 15894005 Common - Predicted membrane protein CAC0717 6 None None None 15893520 Nonpathogen - hypothetical protein CAC0228 1 None None None 15895249 Nonpathogen - Predicted membrane protein CAC1978 1 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 15894673 Common purN phosphoribosylglycinamide formyltransferase CAC1394 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 15894672 Common purM phosphoribosylaminoimidazole synthetase CAC1393 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 15895531 Common addB ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase) CAC2263 34 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 15893578 Common - Uncharacterized membrane protein CAC0286 2 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 15895331 Common scpA segregation and condensation protein A CAC2061 144 COG1354 COG1354, Uncharacterized conserved protein Function unknown 15895557 Common - Biotin carboxyl carrier protein CAC2289 17 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 15895899 Common tig trigger factor CAC2641 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 15893618 Common - recombination factor protein RarA CAC0326 247 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 15894199 Common - Possible non-processive endoglucanase family 5, secreted; CelA homolog secreted; dockerin domain CAC0912 21 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 15895234 Common - Predicted esterase of alpha/beta hydrolase superfamily, YBBA B.subtilis ortholog CAC1962 27 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 15896401 Common - Uncharacterized conserved protein, YACP B.subtilis ortholog CAC3153 28 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 15895193 Common - Phage related SSB-like protein CAC1919 209 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15894347 Common - Uncharcterized protein, shares conserved domain among different RHS family proteins and WAPA of B.subtilis CAC1061 4 None None None 15896928 Common - Uncharacterized conserved membrane protein, YUEB B.subtilis homolog CAC3696 18 COG1511 COG1511, Predicted membrane protein Function unknown 15896823 Common - Uncharacterized conserved membrane protein, YHGE B.subtilis ortholog CAC3589 32 COG1511 COG1511, Predicted membrane protein Function unknown 15893779 Common - hypothetical protein CAC0488 2 None None None 15895297 Nonpathogen - hypothetical protein CAC2027 1 None None None 15895648 Common ssb single-strand DNA-binding protein CAC2382 5 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15896507 Common - ATPase with chaperone activity, ATP-binding domain, diverged CAC3262 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 15895110 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CAC1835 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 15895288 Common - Aldehyde:ferredoxin oxidoreductase CAC2018 58 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 15894380 Common - Uncharacterized protein, YjiN homolog CAC1095 42 COG2733 COG2733, Predicted membrane protein Function unknown 15893674 Common - PTS cellobiose-specific component IIA CAC0383 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 15894081 Common - Nucleoside-diphosphate-sugar epimerase (UDP-glucose 4-epimerase) CAC0794 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15894702 Common - Predicted dehydrogenase of short-chain alcohol dehydrogenase family, ortholog of YHDF B.subtilis CAC1423 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15896667 Common glvG 6-phospho-alpha-glucosidase CAC3426 53 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 15894056 Common - hypothetical protein CAC0769 24 COG3875 COG3875, Uncharacterized conserved protein Function unknown 15896691 Common - hypothetical protein CAC3450 5 None None None 15896581 Common - Predicted transcriptional regulator CAC3338 142 COG1733 COG1733, Predicted transcriptional regulators Transcription 15894982 Common - Periplasmic phosphate-binding protein CAC1705 169 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 15896068 Common - Predicted integrase of XerC/XerD family CAC2813 4 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 15894336 Common - Uncharacterized conserved protein,ortholog of YaaR B.subtilis CAC1049 17 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 15893839 Common - Predicted transcriptional regulator CAC0549 4 COG1396 HipB, Predicted transcriptional regulators Transcription 15895198 Nonpathogen - hypothetical protein CAC1924 1 None None None 15893555 Common serB Phosphoserine phosphatase related protein CAC0263 51 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15895440 Common - Predicted glycosyltransferase CAC2171 186 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15896359 Common rpmJ Ribosomal protein L36 CAC3108 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 15894246 Common clpB ATPase with chaperone activity, two ATP-binding domains CAC0959 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15893770 Common - hypothetical protein CAC0479 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 15895841 Nonpathogen - 6-pyruvoyl-tetrahydropterin synthase related domain; conserved membrane protein CAC2581 10 COG5617 COG5617, Predicted integral membrane protein Function unknown 15894548 Common - Pseudouridylate synthase family protein, yabo B.subtilis ortholog CAC1266 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15896223 Common PatB PLP-dependent aminotransferase, CAC2970 238 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 15895241 Nonpathogen - hypothetical protein CAC1970 1 None None None 15895379 Common - GAF domain-containing protein CAC2110 80 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 15896698 Common - Uncharacterized protein, homolog of B. anthracis (gi:48942631) CAC3458 3 None None None 15896301 Common - AMSJ/WSAK related protein, possibly involved in exopolysaccharide biosynthesis CAC3050 16 COG2327 WcaK, Uncharacterized conserved protein Function unknown 15894742 Common - Predicted transcriptional regulator CAC1463 39 COG1476 COG1476, Predicted transcriptional regulators Transcription 15893561 Common - Uncharacterized membrane protein CAC0269 14 None None None 15894687 Common - Phospho-beta-glucosidase CAC1408 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15896144 Common - Fusion of alpha-glucosidase (family 31 glycosyl hydrolase) and glycosidase (TreA/MalS family) CAC2891 87 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 15896380 Common rplB 50S ribosomal protein L2 CAC3130 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 15893336 Nonpathogen - hypothetical protein CAC0038 1 COG5417 COG5417, Uncharacterized small protein Function unknown 15896435 Common - Predicted nucleic-acid-binding protein protein, containing HHH domain, YACK B.subtilis ortholog CAC3187 28 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 15893737 Common - Hydrolase of MutT (Nudix) family CAC0446 10 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 15895692 Common - hypothetical protein CAC2427 14 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 15896544 Common gerKA Spore germination protein GerKA, membrane protein CAC3300 15 None None None 15894466 Nonpathogen - hypothetical protein CAC1183 1 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 15894461 Nonpathogen - hypothetical protein CAC1178 1 None None None 15895316 Nonpathogen - Predicted membrane protein CAC2046 4 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15896155 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CAC2902 191 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 15895069 Common lexA P-loop ATPase domain fused to LexA-like protein CAC1793 170 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15895828 Common - Predicted transcriptional regulator CAC2568 150 COG1733 COG1733, Predicted transcriptional regulators Transcription 15894644 Common cbiM cobalt transport protein CbiM CAC1365 89 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 15894659 Common cbiF/cobM precorrin-4 methylase cbiF CAC1380 203 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 15895735 Nonpathogen - Uncharacterized Zn-finger protein CAC2470 1 None None None 15895447 Common - Predicted CDP-4-keto-6-deoxy-D-glucose-3-dehydrase CAC2178 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15895273 Common - Predicted permease CAC2003 10 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15896842 Common - ABC-type MDR transport system, ATPase component CAC3608 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15894541 Common rpmA 50S ribosomal protein L27 CAC1259 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 15894397 Nonpathogen - Hypothetical protein, CF-11 family CAC1112 1 None None None 15894129 Common - Hypothetical protein, CF-28 family CAC0842 1 None None None 15896840 Common - Transcriptional regulator, AcrR family CAC3606 35 COG1309 AcrR, Transcriptional regulator Transcription 15896420 Common leuD 3-isopropylmalate dehydratase, small subunit CAC3172 207 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 15893657 Common - Predicted permease CAC0366 66 COG0679 COG0679, Predicted permeases General function prediction only 15894862 Common - ribonuclease Z CAC1584 111 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 15896644 Common - Predicted membrane protein CAC3403 2 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15896327 Common ptb phosphate butyryltransferase CAC3076 157 COG0280 Pta, Phosphotransacetylase Energy production and conversion 15894022 Common - hypothetical protein CAC0735 24 COG4267 COG4267, Predicted membrane protein Function unknown 15895008 Common - Predicted nucleotide-binding protein, YLOS B.subtilis ortholog CAC1731 52 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 15896791 Common - Nitroreductase family protein CAC3555 75 COG0778 NfnB, Nitroreductase Energy production and conversion 15894235 Common - Uncharacterized protein, DegV family CAC0948 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 15896108 Common recD ATP-dependent exoDNAse (exonuclease V), alpha subunit, RecD CAC2854 146 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 15896637 Common - Nudix (MutT) family hydrolase, C4-type Zn-finger domain containing CAC3396 118 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 15894970 Common ftsZ cell division protein FtsZ CAC1693 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 15895054 Common - Amidase from nicotinamidase family CAC1778 36 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 15894652 Common cbiK Anaerobic Cobalt chelatase, cbiK CAC1373 24 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 15895351 Common xseB exodeoxyribonuclease VII small subunit CAC2081 52 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 15893476 Common - Transcriptional regulators of NagC/XylR (ROK) family, sugar kinase CAC0183 63 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 15896909 Common kdpE KDP operon transcriptional regulatory protein KdpE (CheY-like receiver domain and HTH-type DNA-binding domain) CAC3677 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15893570 Common - aspartate kinase CAC0278 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15896550 Nonpathogen - TPR-repeats containing protein CAC3307 1 None None None 15893671 Common - Periplasmic amino acid-binding protein CAC0380 186 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15896203 Common lacR Lactose phosphotransferase system repressor lacR CAC2950 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15895568 Common mrcB Membrane carboxypeptidase mrcB CAC2301 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 15896171 Common pmi Mannose-6 phospate isomelase CAC2918 47 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 15896759 Common - Hypothetical protein, CF-7 family CAC3522 3 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15894401 Nonpathogen - hypothetical protein CAC1116 6 None None None 15894364 Common - Uncharacterized protein, related to enterotoxins of other Clostridiales CAC1079 36 COG5263 COG5263, FOG: Glucan-binding domain (YG repeat) General function prediction only 15895177 Nonpathogen - hypothetical protein CAC1903 1 None None None 15896463 Common mfd Transcription-repair coupling factor, MFD (superfamily II helicase ) CAC3216 242 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 15893446 Common - Predicted SAM dependent methyltransferase CAC0151 33 None None None 15893979 Common - Uncharacterized conserved protein, VanW of Enterococcus faecalis related CAC0691 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 15893908 Common - ABC transporter, periplasmic-binding, putative CAC0620 46 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 15896494 Nonpathogen - hypothetical protein CAC3249 1 None None None 15896614 Common - Uncharacterized conserved membrane protein, YCAP family CAC3372 50 COG2323 COG2323, Predicted membrane protein Function unknown 15895538 Nonpathogen - hypothetical protein CAC2270 1 None None None 15894432 Common - hypothetical protein CAC1149 3 None None None 15894665 Common - Zn-dependent hydrolase, glyoxylase family CAC1386 110 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15894620 Common araD L-ribulose-5-phosphate 4-epimerase CAC1341 113 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 15895203 Common - Uncharacterized protein, MazG family CAC1930 1 COG1694 MazG, Predicted pyrophosphatase General function prediction only 15896798 Common - Mismatch repair protein MutS-like ATPase CAC3563 195 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15895743 Common - Predicted conserved membrane protein, possible homolog of CAAX-like membrane endopeptidase CAC2478 36 None None None 15896466 Common - Membrane associated histidine kinase with HAMP domain CAC3219 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893871 Common - Cobyrinic acid a,c-diamide synthase CobB/CbiA (CBIB protein) CAC0582 146 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 15895384 Common lspA Lipoprotein signal peptidase CAC2115 190 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15894120 Common - ABC-type multidrug transport system (daunorubicin resistance), ATPase component CAC0833 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15893946 Common - Fe-S oxidoreductase CAC0658 87 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 15895012 Common - Predicted kinase related to hydroxyacetone kinase, YLOV ortholog CAC1735 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 15894334 Common - vitamin B12-dependent ribonucleotide reductase CAC1047 192 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15896400 Common - RNA polymerase factor sigma-70 CAC3152 35 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 15896776 Common - hypothetical protein CAC3540 2 None None None 15893428 Nonpathogen - Hypothetical protein, CF-4 family CAC0133 1 None None None 15895163 Nonpathogen - Uncharacterized phage related protein CAC1888 1 None None None 15895099 Common - hypothetical protein CAC1823 120 COG2127 COG2127, Uncharacterized conserved protein Function unknown 15896190 Common - Ketopantoate reductase PanE/ApbA CAC2937 111 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 15896440 Common - Transciptional regulator CTSR CAC3192 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 15896963 Common gidB glucose-inhibited division protein B CAC3732 203 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 15896914 Common kdpA/atkA potassium-transporting ATPase subunit A CAC3682 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 15893453 Common glmS D-fructose-6-phosphate amidotransferase CAC0158 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 15893740 Common - hypothetical protein CAC0449 9 None None None 15896295 Common - CPSD/CAPA conserved membrane protein of Rol/Cld family CAC3044 85 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 15893590 Common - Guanylate kinase CAC0298 19 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 15896850 Common - ABC transport system, ATPase component CAC3616 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15894268 Common pflA Pyruvate-formate-lyase-activating enzyme CAC0981 87 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15893852 Common - Predicted membrane protein CAC0562 2 None None None 15895935 Common - Lytic murein transglycosylase CAC2677 182 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15896723 Common - Multimeric flavodoxin WrbA family protein CAC3486 49 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15894361 Common - Hypothetical protein, CF-32 family CAC1076 8 None None None 15894886 Common - HIT family hydrolase CAC1608 133 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15895824 Common - hypothetical protein CAC2564 6 None None None 15896423 Nonpathogen - hypothetical protein CAC3175 1 None None None 15895000 Common fmt methionyl-tRNA formyltransferase CAC1723 218 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 15895879 Common - Cell wall hydrolase (autolysin), family 25 of glycosyl hydrolase; peptodoglycan-binding domain CAC2621 53 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 15893901 Common - Predicted membrane protein YohJ family CAC0612 80 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 15896445 Common greA transcription elongation factor GreA CAC3198 204 COG0782 GreA, Transcription elongation factor Transcription 15893540 Common - Transposon related protein CAC0248 27 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 15893926 Common - hypothetical protein CAC0638 25 None None None 15895765 Common - hypothetical protein CAC2500 170 COG0344 COG0344, Predicted membrane protein Function unknown 15893519 Common - Predicted permease CAC0227 17 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 15893315 Common serS seryl-tRNA synthetase CAC0017 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15895585 Common - Membrane protein of EXOQ family, involved in exopolysaccharide production CAC2318 60 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 15894134 Common - Probable cation efflux pump (multidrug resistance protein) CAC0847 183 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15894203 Common - Possible non-processive endoglucanase family 9, secreted; CelG ortholog; dockerin and cellulose-binding domain CAC0916 19 None None None 15894891 Common - ABC-type multidrug/protein/lipid transport system, membrane ATPase component CAC1613 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15896418 Common ilvD Dihydroxy-acid dehydratase CAC3170 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15895394 Common divIB Cell division septal protein divIB/FtsQ CAC2125 29 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 15894625 Common araA L-arabinose isomerase CAC1346 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 15895759 Nonpathogen - Predicted membrane protein CAC2494 1 None None None 15896746 Common - Transcriptional regulator, MerR family (duplicated domains) CAC3509 8 COG0789 SoxR, Predicted transcriptional regulators Transcription 15893599 Common - Predicted methyltransferase CAC0307 221 COG0313 COG0313, Predicted methyltransferases General function prediction only 15893992 Common - Sugar ABC transporter, permease protein CAC0704 131 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 15896930 Nonpathogen - Hypothetical protein, CF-44 family CAC3698 1 None None None 15893970 Common nrgA Ammonium transporter (membrane protein nrgA) CAC0682 200 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 15893569 Common - HD-GYP hydrolase domain containing protein CAC0277 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15893504 Common bioY BioY protein precursor CAC0211 110 COG1268 BioY, Uncharacterized conserved protein General function prediction only 15893830 Common - Beta-mannanase ManB-like enzyme, contains ChW-repeats CAC0540 9 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 15894229 Common hisI_1 Phosphoribosyl-AMP cyclohydrolase CAC0942 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 15895633 Common - Predicted membrane protein CAC2366 1 None None None 15894440 Nonpathogen - hypothetical protein CAC1157 1 None None None 15893859 Common sacT SACPA operon antiterminator (sacT) CAC0569 29 COG3711 BglG, Transcriptional antiterminator Transcription 15895603 Common - TPR repeats containing protein CAC2336 22 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15896064 Common - Predicted HD superfamily hydrolase CAC2809 5 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 15896475 Common - NADH:flavin oxidoreductase, Old Yellow Enzyme family CAC3229 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15894722 Nonpathogen - hypothetical protein CAC1443 1 None None None 15894150 Common - Sensory transduction histidine kinase CAC0863 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893957 Common - hypothetical protein CAC0669 2 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 15895029 Common ftsY Signal recognition particle GTPase, FtsY CAC1752 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 15894761 Common - Uncharacterized membrane protein,ortholog of YDFK B.subtilis CAC1482 46 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 15894874 Common malS Malic enzyme CAC1596 199 COG0281 SfcA, Malic enzyme Energy production and conversion 15895463 Common - Protein containing aminopeptidase domain CAC2195 15 COG4310 COG4310, Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain General function prediction only 15893760 Common spmA Spore maturation protein A (gene spmA) CAC0469 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 15894116 Common - Uncharacterized conserved membrane protein, similar to MDR (VANZ) ORF of Enterococcus CAC0829 11 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 15894479 Nonpathogen - hypothetical protein CAC1196 1 None None None 15893364 Common - (FS) similar to ABC transporter (permease), YXDM B.subtilis ortholog CAC0067 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15894889 Common - Probable cation efflux pump (multidrug resistance protein) CAC1611 134 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15895748 Common - Methyl-accepting chemotaxis protein CAC2483 106 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15895750 Common - Predicted membane protein, probable cation efflux pump (MDR-type) CAC2485 98 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15895904 Common sipS Signal peptidase I CAC2646 179 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15896104 Common - Proline/glycine betaine ABC-type transport system, ATPase component CAC2850 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 15895139 Nonpathogen - hypothetical protein CAC1864 1 None None None 15896056 Common - TPR-repeat-containing protein, secreted CAC2801 9 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15896316 Common - Possible O-antigen/teichoic acid transporter CAC3065 63 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15895599 Common spsJ DTDP-D-glucose 4,6-dehydratase CAC2332 234 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 15895997 Common hisS histidyl-tRNA synthetase CAC2740 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15894542 Common obgE GTPase ObgE CAC1260 249 COG0536 Obg, Predicted GTPase General function prediction only 15894387 Nonpathogen - Predicted membrane protein CAC1102 1 None None None 15894583 Common - Predicted membrane protein CAC1301 2 None None None 15895769 Common - hypothetical protein CAC2504 4 None None None 15893735 Common napA Na/H antiporter (napA) CAC0444 213 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15893874 Common - N-terminal CheY reciever domain fused to C-terminal uncharacterized CheX-like domain CAC0585 212 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15896118 Common atpC FoF1-type ATP synthase epsilon subunit CAC2864 140 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 15896069 Nonpathogen - Predicted membrane protein CAC2814 1 None None None 15896921 Common - Uncharacterized conserved protein, phnB family CAC3689 65 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 15895441 Common - Predicted glycosyltransferase CAC2172 171 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15896431 Common - Oligopeptide ABC transporter, ATPase component CAC3183 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 15893353 Nonpathogen - hypothetical protein CAC0056 1 None None None 15895611 Common - LPS biosynthesis protein , RfbU family CAC2344 3 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15896512 Common - Specialized sigma subunit of RNA polymerase CAC3267 164 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 15896814 Common - Dioxygenase related to 2-nitropropane dioxygenase CAC3580 134 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 15893896 Common - putative aminopeptidase 2 CAC0607 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 15895257 Nonpathogen - hypothetical protein CAC1986 2 None None None 15894007 Common - Epoxide hydrolase, similar to eukaryotic CAC0719 62 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15895033 Common - hypothetical protein CAC1756 69 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 15896199 Common - hypothetical protein CAC2946 2 None None None 15896363 Common secY preprotein translocase subunit SecY CAC3113 229 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 15896653 Common - Predicted protein-S-isoprenylcysteine methyltransferase CAC3412 29 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 15895022 Common rpmF 50S ribosomal protein L32 CAC1745 76 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 15894511 Common cisA Site-specific DNA recombinase CAC1228 97 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15894977 Common - Response regulator (CheY-like receiver domain and DNA-binding HTH domain) CAC1700 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15894303 Common - SpoVB related membrane protein CAC1016 95 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15893714 Common - Fusion: PTS system, beta-glucosides specific IIABC component CAC0423 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15895305 Nonpathogen - Hypothetical protein, CF-23 family CAC2035 1 None None None 15894731 Common - MDR-type permease CAC1452 225 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896709 Nonpathogen - hypothetical protein CAC3470 1 None None None 15895009 Nonpathogen - hypothetical protein CAC1732 1 None None None 15895337 Nonpathogen - hypothetical protein CAC2067 1 None None None 15893666 Common patA aminotransferase A CAC0375 242 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15896201 Common - ATPase components of ABC transporter with duplicated ATPase domains (second domain is inactivated) CAC2948 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15896487 Common - Uncharacterized Fe-S protein, PflX (pyruvate formate lyase activating protein) homolog CAC3242 47 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 15895588 Common - Predicted glycosyltransferase CAC2321 164 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15893767 Common pepT peptidase T CAC0476 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 15895207 Common - hypothetical protein CAC1934 5 None None None 15896501 Common - Predicted acetyltransferase CAC3256 31 COG0456 RimI, Acetyltransferases General function prediction only 15895705 Common - Predicted membrane protein CAC2440 7 None None None 15896004 Common - Protein containing LysM repeats (N-terminal domain) and domain related to chitinase CAC2747 92 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 15894613 Common - Fe-S oxidoreductase of MoeA/NarA subfamily CAC1334 97 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 15895086 Common dapG aspartate kinase I CAC1810 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15896026 Common - Amino acid transporter CAC2771 143 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15893803 Common - hypothetical protein CAC0512 98 COG0391 COG0391, Uncharacterized conserved protein Function unknown 15894678 Common - ABC transporter, permease component CAC1399 163 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 15895848 Common - Glycosyltransferase CAC2588 171 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894640 Common bioD dithiobiotin synthetase CAC1361 177 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 15896130 Common - Deoxycytidylate deaminase CAC2876 68 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 15893634 Common - Hypothetical protein, CF-23 family CAC0343 2 None None None 15896075 Common - Predicted permease CAC2820 136 COG2252 COG2252, Permeases General function prediction only 15895374 Common - General secretion pathway protein F CAC2104 150 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 15893417 Common cheR Chemotaxis protein methyltransferase (cheR) CAC0121 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 15894496 Nonpathogen - Predicted membrane protein CAC1213 1 None None None 15896285 Common - MutS-like mismatch repair protein, ATPase CAC3034 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15894850 Common - Fructose-1,6-bisphosphatase (YYDE B.subtils ortholog) CAC1572 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 15895217 Common - hypothetical protein CAC1944 1 None None None 15896520 Common - Possible surface protein, responsible for cell interaction; contains cell adhesion domain and ChW-repeats CAC3275 32 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15893701 Common - Uncharacterized small conserved protein, homolog of YUKE/YFJA CAC0410 4 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15893497 Common srta Sortase (surface protein transpeptidase), YHCS B.subtilis ortholog CAC0204 37 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 15893759 Common - HAD superfamily hydrolase CAC0468 28 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15894663 Common cobS cobalamin synthase CAC1384 150 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 15895681 Nonpathogen - hypothetical protein CAC2415 5 COG3330 COG3330, Uncharacterized protein conserved in bacteria Function unknown 15895923 Common - putative deoxyribonucleotide triphosphate pyrophosphatase CAC2665 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 15896594 Common - Uncharacterized membrane protein, YCBP B.subtilis ortholog CAC3351 4 None None None 15894950 Common gltA Large subunit of NADH-dependent glutamate synthase CAC1673 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 15895688 Common - Oxygen-independent coproporphyrinogen III oxidase, Fe-S oxidoreductase CAC2422 60 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15895047 Common - Uncharacterized protein, ykrI B.subtilis homolog CAC1771 2 None None None 15896355 Common rpoA DNA-directed RNA polymerase subunit alpha CAC3104 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 15895921 Common - Protein containing cell-wall hydrolase domain CAC2663 139 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15895102 Nonpathogen - hypothetical protein CAC1826 1 None None None 15894198 Common - Possible processive endoglucanase family 48, secreted; CelF ortholog; dockerin domain CAC0911 9 None None None 15894783 Nonpathogen - hypothetical protein CAC1505 1 None None None 15895418 Common fliQ Flagellar biosynthesis protein FliQ CAC2149 77 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 15894814 Common - Transcriptional regulator, AcrR family CAC1536 40 COG1309 AcrR, Transcriptional regulator Transcription 15895958 Common guaB inositol-5-monophosphate dehydrogenase CAC2701 244 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15896079 Common - N-terminal HKD family nuclease fused to DNA/RNA helicases of superfamily II,conserved in Streptomyces CAC2824 156 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 15893981 Common - Transcriptional regulator of the LacI family CAC0693 132 COG1609 PurR, Transcriptional regulators Transcription 15894044 Common - Predicted membrane protein CAC0757 9 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 15895488 Common cheA Chemotaxis histidine kinase, CheA (contains CheW-like adaptor domain) CAC2220 162 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 15896732 Common - Multimeric flavodoxin WrbA family protein CAC3495 47 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15893362 Nonpathogen - hypothetical protein CAC0065 1 None None None 15896260 Common - CBS domain containing protein CAC3008 5 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 15896508 Nonpathogen - hypothetical protein CAC3263 1 None None None 15896453 Common - hypothetical protein CAC3206 71 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 15893403 Common - ABC-type sulfate transporter, ATPase component CAC0107 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 15893425 Common bofA BofA B.subtilis ortholog, SigmaK-factor processing regulatory protein CAC0129 10 None None None 15894806 Nonpathogen - Predicted membrane protein CAC1528 1 None None None 15896232 Common aspC aspartyl-tRNA synthetase CAC2979 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15894517 Common pheB hypothetical protein CAC1234 14 COG4492 PheB, ACT domain-containing protein General function prediction only 15894083 Common - CDP-diglyceride synthetase CAC0796 14 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 15895663 Nonpathogen - hypothetical protein CAC2397 1 None None None 15894759 Common - Predicted dehydrogenase CAC1480 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15896860 Common folE GTP cyclohydrolase I CAC3626 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 15895107 Common lexA LexA repressor CAC1832 175 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15893535 Common - Predicted permease CAC0243 103 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15893465 Common - Predicted permease CAC0171 6 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15896533 Common - Iron-regulated ABC transporter ATPase subunit (SufC), VEG296 B.subtilis ortholog CAC3288 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 15896836 Nonpathogen - HD superfamily hydrolase CAC3602 7 None None None 15896774 Common - Metallo-beta-lactamase superfamily hydrolase CAC3538 59 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 15894600 Common glpP Glycerol-3-phosphate responsive antiterminator (mRNA-binding), GLPP CAC1320 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 15895837 Common - GGDEF domain containing protein, (inactivated) CAC2577 1 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15895565 Common - Predicted nucleotidyltransferase CAC2298 2 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 15896879 Common - Predicted transcriptional regulator, containing DNA-binding domain of xre family CAC3646 10 COG1396 HipB, Predicted transcriptional regulators Transcription 15895854 Nonpathogen - hypothetical protein CAC2595 1 None None None 15895392 Common sbp Small basic protein, sbp, uncharacterized CAC2123 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 15896678 Common - Predicted membrane-associated Zn-dependent protease, HtpX family (BlaR subfamily) CAC3437 28 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 15895145 Nonpathogen - hypothetical protein CAC1870 1 None None None 15893750 Common - NtrC family transcriptional regulator (PAS and AAA domains) CAC0459 168 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 15895327 Common - D-alanyl-D-alanine carboxypeptidase CAC2057 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15896721 Common - Short-chain alcohol dehydrogenase family protein CAC3484 226 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 15895673 Common - CheY-like receiver domain of response regulator CAC2407 188 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15895798 Common - Predicted protein of beta-propeller fold CAC2535 94 COG3391 COG3391, Uncharacterized conserved protein Function unknown 15895455 Common - Glycosyltransferase CAC2186 36 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 15894691 Common cdrC Methyl methane sulfonate/mytomycin C/UV resistance protein, GSP18 (YCEE) B.subtilis ortholog, TerE family protein CAC1412 29 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 15896968 Common - Uncharacterized conserved protein, YidD family CAC3737 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 15893999 Common tpiA triosephosphate isomerase CAC0711 224 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 15895949 Common - D-lactate dehydrogenase CAC2691 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15894028 Common - Methyl-accepting chemotaxis protein CAC0741 123 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15895594 Common - Glycosyltransferase domain containing protein CAC2327 161 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15893303 Common - Uncharacterized small conserved protein, ortholog of YAAB B.subtilis CAC0005 11 None None None 15894507 Nonpathogen - hypothetical protein CAC1224 1 None None None 15896948 Common rplI 50S ribosomal protein L9 CAC3717 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 15895912 Common pyrB aspartate carbamoyltransferase catalytic subunit CAC2654 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 15895807 Nonpathogen - hypothetical protein CAC2545 1 None None None 15896257 Common add adenosine deaminase CAC3005 117 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 15896230 Common gatA Glutamyl-tRNAGln amidotransferase subunit A CAC2977 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 15894097 Common hypF Hydrogenase maturation factor (hypF) CAC0810 115 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15896313 Common - CPSB/CAPC ortholog, PHP family hydrolase CAC3062 41 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15893532 Common - Response regulator (CheY-like recever domain and HTH DNA-binding domain) CAC0240 219 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15896213 Common GalE UDP-galactose 4-epimerase CAC2960 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 15896062 Common - Endo-1,3(4)-beta-glucanase family 16 CAC2807 16 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 15896174 Common thiH thiamine biosynthesis protein ThiH CAC2921 62 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 15895541 Common - D-tyrosyl-tRNA deacylase CAC2273 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 15894183 Common aroC chorismate synthase CAC0896 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 15895402 Common - hypothetical protein CAC2133 127 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 15894753 Common - Proline/glycine betaine ABC transport system, periplasmic component CAC1474 91 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 15895832 Common - Possible aminoglycoside phosphotransferase (protein kinase related), diverged CAC2572 9 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 15893829 Common manB Beta-mannanase ManB, contains ChW-repeats CAC0539 18 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 15895040 Common - hypothetical protein CAC1763 131 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 15894572 Common - Uncharacterized protein, homolog of YQFC B.subtilis CAC1290 11 None None None 15896377 Common rpsC 30S ribosomal protein S3 CAC3127 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 15894694 Common - TerC family protein, ortholog of stress responce protein CAC1415 145 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15895984 Common - hypothetical protein CAC2727 31 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 15894344 Common - Uncharcterized protein, shares conserved domain among different RHS family proteins and WAPA of B.subtilis CAC1057 28 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15896346 Common thiK Hydroxyethylthiazole kinase ThiM/ThiK (FS!) CAC3095 222 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 15896138 Common prfA peptide chain release factor 1 CAC2884 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 15893516 Common - Response regulator (CheY-like receiver domain and HTH DNA-binding domain) CAC0224 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15894609 Common - Metal-dependent hydrolase of the beta-lactamase superfamily, possible sulfatase CAC1330 27 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 15895508 Common - Protein shares with cyclomaltodextrin glucanotransferase C-terminal domain CAC2240 12 None None None 15896819 Common - ABC-type transporter, ATPase component CAC3585 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15895724 Common - 2-oxoacid:ferredoxin oxidoreductase, alpha subunit CAC2459 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15894957 Common - Holliday junction resolvase-like protein CAC1680 180 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 15893596 Common motA Chemotaxis motility protein A, gene motA CAC0304 109 COG1291 MotA, Flagellar motor component Cell motility and secretion 15895521 Common - Membrane-associated sensory histidine kinase-like ATPase CAC2253 93 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 15896604 Common - Transcriptional regulator, LysR family CAC3361 192 COG0583 LysR, Transcriptional regulator Transcription 15894828 Common - methionine sulfoxide reductase B CAC1550 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15896270 Common - Rubrerythrin CAC3018 78 COG1592 COG1592, Rubrerythrin Energy production and conversion 15894997 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase CAC1720 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 15895427 Common fliJ Flagellar protein FliJ CAC2158 1 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15895353 Common folD Tetrahydrofolate dehydrogenase/cyclohydrolase, FolD CAC2083 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 15896802 Common accA Acetyl-CoA carboxylase alpha subunit CAC3568 180 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 15893682 Common - Cystathionine beta-lyase CAC0391 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15896408 Common trpC Indole-3-glycerol phosphate synthase CAC3160 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 15894163 Common - Transcriptional regulator, MarR/EmrR family CAC0876 27 COG1846 MarR, Transcriptional regulators Transcription 15895561 Nonpathogen - Hypothetical secreted protein CAC2293 1 None None None 15893498 Common - Predicted phosphohydrolase, Icc family CAC0205 25 COG1409 Icc, Predicted phosphohydrolases General function prediction only 15894094 Common - Cold shock protein CAC0807 180 COG1278 CspC, Cold shock proteins Transcription 15894903 Common - Phosphoserine phosphatase family protein CAC1625 14 COG4359 COG4359, Uncharacterized conserved protein Function unknown 15894288 Common - aspartate aminotransferase CAC1001 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15894990 Common - Coat morphogenesis sporulation protein spoIVA CAC1713 15 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 15896954 Common ssb Single strand DNA binding protein, SSB CAC3723 212 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15896248 Common - Superfamily II DNA/RNA helicase, SNF2 family CAC2996 146 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 15896688 Common - Protein-disulfide isomerase DsbC/DsbG CAC3447 86 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 15893378 Common - Predicted membrane protein CAC0082 7 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 15895076 Common - Uncharacterized conserved protein, YLXR B.subtilis homolog CAC1800 51 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 15893865 Nonpathogen - hypothetical protein CAC0576 1 None None None 15896608 Nonpathogen - hypothetical protein CAC3365 1 None None None 15894395 Common - Integrase/recombinase (xerC/xerD family); CF-10 family CAC1110 76 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15894231 Common tkt Transketolase CAC0944 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15894942 Common - Predicted amidohydrolase CAC1665 198 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15896865 Common oppB Oligopeptide ABC transporter, permease component CAC3631 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15894430 Nonpathogen - hypothetical protein CAC1147 1 None None None 15893338 Common - Uncharacterized small conserved protein, homolog of yfjA/yukE B.subtilis CAC0040 9 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15894142 Common - Predicted phosphatase CAC0855 207 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15896491 Nonpathogen - hypothetical protein CAC3246 1 None None None 15894414 Nonpathogen - hypothetical protein CAC1130 1 None None None 15896443 Common - glycyl-tRNA synthetase CAC3195 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15894480 Common - hypothetical protein CAC1197 7 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15896208 Common lacR Lactose phosphotransferase system repressor lacR CAC2955 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15895263 Common moaA Molybdenum cofactor biosynthesis enzyme MoaA, Fe-S oxidoreductase CAC1993 203 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15895552 Common ruvB Holliday junction DNA helicase B CAC2284 226 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 15896164 Common - Glycosyltransferase CAC2911 219 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15894749 Common - 2-Hydroxy-6-Oxo-6-Phenylhexa-2,4-Dienoate hydrolase CAC1470 1 None None None 15894429 Nonpathogen - hypothetical protein CAC1146 1 None None None 15894602 Common glpA Glycerol-3-phosphate dehydrogenase, GLPA CAC1322 156 COG0579 COG0579, Predicted dehydrogenase General function prediction only 15896734 Common - hypothetical protein CAC3497 4 None None None 15894333 Common - Transcriptional regulator, LysR family CAC1046 193 COG0583 LysR, Transcriptional regulator Transcription 15896809 Common fabD acyl-carrier-protein S-malonyltransferase CAC3575 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 15893584 Common - hypothetical protein CAC0292 3 None None None 15894226 Common hisH imidazole glycerol phosphate synthase subunit HisH CAC0939 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 15894838 Nonpathogen - hypothetical protein CAC1560 1 None None None 15895511 Common asnB N-terminal domain of asparagine synthase CAC2243 166 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 15893529 Common - ABC transporter, permease component CAC0237 16 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15896167 Common panB Ketopantoate hydroxymethyltransferase CAC2914 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 15895262 Common moaC molybdenum cofactor biosynthesis protein C CAC1992 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15893626 Common - Hypothetical protein, CF-21 family CAC0334 2 None None None 15896894 Common - Glycosyltransferase CAC3661 192 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15896265 Common - hypothetical protein CAC3013 14 COG5482 COG5482, Uncharacterized conserved protein Function unknown 15893937 Common - Uncharacterized protein, homolog of Thermotoga maritima (4982386) CAC0649 5 None None None 15895546 Common secD preprotein translocase subunit SecD CAC2278 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 15895083 Common rpsO 30S ribosomal protein S15 CAC1807 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 15896120 Common atpG F0F1 ATP synthase subunit gamma CAC2866 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 15896559 Common - Possible cardiolipin synthase (phospholipase D family) CAC3316 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15896821 Common - DNA replication protein DnaD CAC3587 17 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 15893689 Common - Uncharacterized small conserved protein, homolog of YUKE/YFJA B.subtilis CAC0398 5 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15896711 Common - Protein containing transcriptional regulator domain CAC3472 11 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 15895529 Common - HD-hydrolase domain containing protein, YHAM B.subtilis ortholog CAC2261 46 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 15893325 Common pyrE orotate phosphoribosyltransferase CAC0027 123 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 15893695 Common - Serine/threonine protein kinase fused to TPR repeats domain CAC0404 157 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 15896433 Common - Membrane-associated protein containing a homolog of PilT-like ATPase N-terminal domain, YACL B.subtilis ortholog CAC3185 44 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 15895479 Common flgL Flagellin CAC2211 103 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15895783 Common - Extracellular neutral metalloprotease, NPRE (fragment or C-term. domain) CAC2518 5 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 15896482 Common - Possible transcriptional regulator from YAEG/LRPR family CAC3236 13 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 15895156 Nonpathogen - hypothetical protein CAC1881 2 None None None 15894422 Nonpathogen - hypothetical protein CAC1138 1 None None None 15896022 Common - hypothetical protein CAC2767 6 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 15893371 Common - Ferredoxin CAC0075 44 None None None 15894962 Common - Uncharacterized protein from YceG family CAC1685 186 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 15893483 Common - Beta-lactamase CAC0190 47 COG2367 PenP, Beta-lactamase class A Defense mechanisms 15894039 Common - Homolog of eukaryotic DNA ligase III CAC0752 10 COG1423 COG1423, ATP-dependent DNA ligase, homolog of eukaryotic ligase III DNA replication, recombination, and repair 15894793 Common asrC Anaerobic sulfite reduction protein C, reductase CAC1515 136 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 15896719 Common - Predicted permease CAC3482 109 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15893795 Common - FHA-domain containing secreted protein CAC0504 67 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 15895624 Common pheS phenylalanyl-tRNA synthetase subunit alpha CAC2357 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 15895608 Common - Collagenase family protease CAC2341 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15893912 Nonpathogen - hypothetical protein CAC0624 1 None None None 15895646 Common - PLP-dependent aminotransferase CAC2380 242 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15896961 Common soj Chromosome partitioning MinD-family ATPase, SOJ CAC3730 226 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15894063 Common - NCAIR mutase (PurE)-related protein CAC0776 64 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 15893470 Common appB Oligopeptide transport permease protein CAC0177 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15895119 Nonpathogen - hypothetical protein CAC1844 1 None None None 15895961 Common groES Co-chaperonin GroES, HSP10 family CAC2704 213 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 15895968 Common bcd Butyryl-CoA dehydrogenase CAC2711 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 15894174 Common adeC Adenine deaminase CAC0887 78 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 15895064 Common tsf elongation factor Ts CAC1788 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 15896370 Common rpsN 30S ribosomal protein S14 CAC3120 180 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 15894076 Common fhuB permease CAC0789 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15896571 Common - Predicted membrane protein CAC3328 2 None None None 15895651 Common - hypothetical protein CAC2385 4 None None None 15895897 Common clpX ATP-dependent protease ATP-binding subunit CAC2639 229 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 15896543 Common bdhA NADH-dependent butanol dehydrogenase A (BDH I) CAC3299 172 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 15895436 Common - Flagellin family protein CAC2167 114 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15896628 Common - Pectate lyase CAC3387 20 None None None 15894464 Nonpathogen - Phage related protein, YorF B.subtilis homolog CAC1181 1 None None None 15893962 Common - L-serine dehydratase, alpha chain CAC0674 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 15894213 Common - TPR-repeat-containing protein CAC0926 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15895472 Common - hypothetical protein CAC2204 1 None None None 15893331 Common - ABC1 family protein kinase CAC0033 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 15894937 Common - butyrate kinase CAC1660 134 COG3426 COG3426, Butyrate kinase Energy production and conversion 15896416 Nonpathogen - Predicted membrane protein CAC3168 1 None None None 15896011 Common - MDR-type ABC transporter (membrane associated ATPase) CAC2755 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15893572 Common - Molybdate transport system, permease component CAC0280 183 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 15895493 Common - hypothetical protein CAC2225 31 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 15894763 Common - Nitroreductase family protein CAC1484 78 COG0778 NfnB, Nitroreductase Energy production and conversion 15896783 Common - hypothetical protein CAC3547 10 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 15893716 Common sacA Sucrase-6-phosphate hydrolase (gene sacA) CAC0425 54 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 15894301 Common - IAA-like amino acid hydrolase CAC1014 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 15896696 Common - Uncharacterized conserved protein, bioY family CAC3456 104 COG1268 BioY, Uncharacterized conserved protein General function prediction only 15894260 Common argG argininosuccinate synthase CAC0973 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 15896875 Common - Oligopeptide ABC transporter, ATPase component CAC3642 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15894884 Nonpathogen - hypothetical protein CAC1606 17 COG2454 COG2454, Uncharacterized conserved protein Function unknown 15893306 Common - Predicted HD superfamily hydrolase CAC0008 4 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15894489 Nonpathogen - Predicted membrane protein CAC1206 1 None None None 15894562 Common hrcA heat-inducible transcription repressor CAC1280 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 15893772 Common nrdG Anaerobic ribonucleoside-triphosphate reductase activating protein, gene nrdG CAC0481 88 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 15893678 Nonpathogen - hypothetical protein CAC0387 1 None None None 15894657 Common cbiT Precorrin-6B methylase CbiT CAC1378 118 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 15895995 Common - hypothetical protein CAC2738 72 COG2013 COG2013, Uncharacterized conserved protein Function unknown 15896325 Common - hypothetical protein CAC3074 12 COG5652 COG5652, Predicted integral membrane protein Function unknown 15896658 Common - Flavodoxin CAC3417 32 COG0716 FldA, Flavodoxins Energy production and conversion 15895913 Common - Uncharacterized membrane-associated protein, DedA family CAC2655 169 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15894864 Common - Integral membrane protein possibly involved in chromosome condensation CAC1586 114 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 15896646 Common - ABC-type MDR transporter, ATPase component CAC3405 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15893899 Nonpathogen - hypothetical protein CAC0610 1 None None None 15895068 Common cdsA CDP-diglyceride synthetase CAC1792 169 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 15895290 Common moeA Molybdopterin biosynthesis enzyme, MoeA, fused to molibdopterin-binding domain CAC2020 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 15894784 Common phoP Response regulator (CheY-like receiver domain and a HTH) CAC1506 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895314 Nonpathogen - hypothetical protein CAC2044 1 None None None 15895737 Common - Alpha/beta superfamily hydrolase CAC2472 11 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15896635 Common - Uncharacterized conserved protein, YGIN family CAC3394 29 COG1359 COG1359, Uncharacterized conserved protein Function unknown 15896084 Nonpathogen - Predicted membrane protein CAC2829 1 None None None 15893873 Common - Precorrin-6B methylase 1 CobL1/CbiE CAC0584 68 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 15893411 Common - Uncharacterized protein, Yje/RRF2 family CAC0115 80 COG1959 COG1959, Predicted transcriptional regulator Transcription 15894020 Common - Predicted membrane protein CAC0733 8 COG4878 COG4878, Uncharacterized protein conserved in bacteria Function unknown 15894770 Common - Predicted ATPase CAC1491 33 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 15893718 Common - Glycerol-3-phosphate ABC-transporter, permease component CAC0427 149 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 15894561 Common hemN coproporphyrinogen III oxidase CAC1279 218 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15894527 Common - Predicted membrane protein CAC1244 9 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 15893611 Common - ABC transporter ATP-binding protein CAC0319 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15893761 Common spmB Spore maturation protein B (gene spmB) CAC0470 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 15895458 Common - putative carbamoyl phosphate synthase large subunit CAC2189 96 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15895536 Common - Uncharacterized protein of YOHL family CAC2268 91 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 15894955 Common alaS alanyl-tRNA synthetase CAC1678 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15894711 Common - Undecaprenyl pyrophosphate synthase related enzyme CAC1432 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15895175 Nonpathogen - hypothetical protein CAC1901 1 None None None 15896496 Common - Sensory transduction protein containing HD_GYP domain CAC3251 123 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 15896741 Common - Transcriptional regulator, AcrR family CAC3504 7 COG1309 AcrR, Transcriptional regulator Transcription 15896757 Common - ABC-type transport system, ATPase component CAC3520 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15894538 Common - Ribonuclease G/E family protein CAC1256 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 15893944 Common - Predicted transposase (3' fragment) CAC0656 12 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 15894122 Common - Predicted integral membrane protein CAC0835 25 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15895933 Common - Uncharcterized protein, YECD B.subtilis homolog CAC2675 20 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 15894646 Common cbiQ Cobalt permease CAC1367 65 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15896303 Common - Glycosyltransferase CAC3052 215 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15893698 Common - PP2C phosphatase family CAC0407 131 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 15895187 Common - Zn-finger containing protein CAC1913 1 COG1996 RPC10, DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) Transcription 15896616 Common - Predicted acetyltransferase CAC3374 11 COG0456 RimI, Acetyltransferases General function prediction only 15894650 Common - Possible kinase, diverged CAC1371 17 COG4542 PduX, Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase Secondary metabolites biosynthesis, transport, and catabolism 15893414 Common cheA Chemotaxis protein cheA CAC0118 151 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 15896461 Common - Stage V sporulation protein T, AbrB family transcriptional regulator CAC3214 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 15896361 Common - Ribosomal protein L14E (archaeal/eukaryotic type) CAC3110 6 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 15894192 Common - Uncharacterized NAD(FAD)-dependent dehydrogenase CAC0905 91 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15896853 Common - Amino acid ABC transporter, permease component CAC3619 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15896916 Common - Polygalacturonase CAC3684 33 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 15896089 Common - Uncharacterized conserved protein, YHAD family CAC2834 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 15896227 Common - Predicted protease from collagenase family CAC2974 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15894546 Common lytR Membrane bound transcriptional regulator of LytR family CAC1264 65 COG1316 LytR, Transcriptional regulator Transcription 15894670 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase CAC1391 186 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 15894939 Common - hypothetical protein CAC1662 2 None None None 15893747 Common lonA ATP-dependent protease (lonA) CAC0456 228 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 15895382 Common pyrR pyrimidine regulatory protein PyrR CAC2113 108 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 15894271 Common - ABC transporter, ATP-binding protein CAC0984 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 15893798 Common - Predicted metal-dependent membrane hydrolase CAC0507 5 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 15893721 Common - Glycerophosphoryl diester phosphodiesterase CAC0430 164 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 15895642 Common oppB Oligopeptide ABC-type transporter, permease CAC2375 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15895712 Nonpathogen - hypothetical protein CAC2447 1 None None None 15893903 Common - Spore coat protein F CAC0614 4 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 15895572 Common SpoVAC Stage V sporulation AC, SpoVAC CAC2305 15 None None None 15894675 Common purD phosphoribosylamine--glycine ligase CAC1396 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 15893510 Common pheA Prephenate dehydrotase (pheA) CAC0217 211 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 15893546 Nonpathogen nifHD Nitrogen regulatory protein PII (nitrogen fixation nifHD) CAC0254 18 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15895518 Common - UDP-glucose pyrophosphorylase CAC2250 229 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15896956 Common - Uncharacterized protein, homolog of Streptococcus pneumoniae (gi:2109447) CAC3725 27 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 15895618 Nonpathogen - Glycosyltransferase CAC2351 6 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15896686 Common - Predicted acetyltransferase CAC3445 19 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 15896472 Common murC UDP-N-acetylmuramate--L-alanine ligase CAC3225 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 15896277 Common - Conserved membrane protein, possible permease, YHCI B.subtilis ortholog CAC3025 6 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15894071 Common - ATP-dependent RNA helicase, superfamily II CAC0784 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15894740 Nonpathogen - Predicted membrane protein CAC1461 1 None None None 15893334 Nonpathogen - Predicted membrane protein, containing FHA domain CAC0036 8 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 15896225 Common nifS Possible cysteine desulphurase from NifS family CAC2972 241 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 15895587 Common - Predicted glycosyltransferase CAC2320 174 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15896583 Common - Uncharacterized conserved domain seen in the bacterial SpoT CAC3340 78 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 15896505 Common asnC asparaginyl-tRNA synthetase CAC3260 240 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15894153 Common - ABC-type multidrug transport system, ATPase component CAC0866 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15894016 Common - hypothetical protein CAC0729 3 None None None 15895649 Common - Predicted xylanase/chitin deacetylase CAC2383 129 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15894846 Common - Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) CAC1568 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15896849 Common - Uncharacterized conserved membrane protein, possible permease CAC3615 5 None None None 15895993 Common sbcC ATPase involved in DNA repair CAC2736 179 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 15896180 Common folA/folK Dihydroneopterin aldolase fused to 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase CAC2927 185 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 15894389 Nonpathogen - hypothetical protein CAC1104 1 None None None 15895303 Nonpathogen - hypothetical protein CAC2033 1 None None None 15895131 Common - Ribonuclease HI CAC1856 10 COG3341 COG3341, Predicted double-stranded RNA/RNA-DNA hybrid binding protein General function prediction only 15894627 Common - Transketolase, TKT CAC1348 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15894450 Nonpathogen - hypothetical protein CAC1167 1 None None None 15895232 Common - Uncharacterized protein, YYAC B.subtilis homolog CAC1960 14 None None None 15896382 Common rplD 50S ribosomal protein L4 CAC3132 217 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 15894033 Common - Secreted protease metal-dependent protease CAC0746 27 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 15893832 Common - Methyl-accepting chemotaxis protein CAC0542 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896395 Common rplA 50S ribosomal protein L1 CAC3147 227 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 15895180 Nonpathogen - hypothetical protein CAC1906 1 None None None 15895694 Nonpathogen - Predicted membrane protein CAC2429 1 None None None 15895443 Common - Glycosyltransferase CAC2174 217 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15895767 Common - Predicted permease CAC2502 8 None None None 15894893 Common - Predicted glycosyltransferase CAC1615 7 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894118 Common - Sensory transduction histidine kinase CAC0831 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 15895291 Common moeA Molybdopterin biosynthesis enzyme, MoeA (short form) CAC2021 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 15895530 Common addA ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains) CAC2262 230 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 15896584 Common - Multimeric flavodoxin WrbA family protein CAC3341 41 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15895481 Common - hypothetical protein CAC2213 1 None None None 15895826 Common - Possible rRNA methylase (SAM-dependent methyltransferase superfamily), YTQB B.subtilis CAC2566 30 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 15893614 Common - Sensory protein, containing EAL-domain CAC0322 154 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15894985 Common - ATPase component of ABC-type phosphate transport system CAC1708 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 15895874 Common - Predicted iron-dependent transcription repressor CAC2616 85 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 15895035 Common trmD tRNA (guanine-N(1)-)-methyltransferase CAC1758 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 15894639 Common bioY Uncharacterized protein of BioY family CAC1360 112 COG1268 BioY, Uncharacterized conserved protein General function prediction only 15896572 Common - Putative Mn transporter, NRAMP family CAC3329 95 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 15895902 Common carB carbamoyl phosphate synthase large subunit CAC2644 239 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15896707 Common uvrC Excinuclease ABC, subunit C (uvrC) CAC3468 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15895814 Common - Predicted transcriptional regulator CRO family CAC2552 49 COG3655 COG3655, Predicted transcriptional regulator Transcription 15896092 Common - Fusion HD-GYP domain and HD-hydrolase domain CAC2837 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15894580 Common - Uncharacterized protein, related to B.subtilis spore coat protein COTS CAC1298 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 15894832 Common - Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein CAC1554 88 COG4633 COG4633, Uncharacterized protein conserved in bacteria Function unknown 15895791 Common - Multimeric flavodoxin WrbA fused to cytochrome c-like domain CAC2528 21 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15894469 Nonpathogen - hypothetical protein CAC1186 1 None None None 15893773 Common - Zn-dependent hydrolase of the metallo-beta-lactamase superfamily CAC0482 95 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 15895020 Common askA Acetate kinase CAC1743 162 COG0282 ackA, Acetate kinase Energy production and conversion 15895461 Common - Ucharacterized protein, CGEB homolog CAC2193 12 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 15896215 Common - Transcriptional regulators of the LacI family CAC2962 129 COG1609 PurR, Transcriptional regulators Transcription 15894708 Common galE UDP-glucose 4-epimerase CAC1429 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 15896812 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III CAC3578 226 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 15896002 Common - Membrane associated methyl-accepting chemotaxis protein CAC2745 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15895770 Common - Uncharacterized membrane protein, YXJN B.subtilis homolog CAC2505 2 None None None 15894009 Common - Predicted membrane protein; CF-9 family CAC0722 6 None None None 15893703 Common - TPR-repeat-containing protein CAC0412 122 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15894038 Common - Permease CAC0751 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 15893964 Common pssA Phosphatidylserine synthase CAC0676 152 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 15896891 Common - Uncharacterized conserved membrane protein, SapB/MtgC family CAC3658 73 COG1285 SapB, Uncharacterized membrane protein Function unknown 15896518 Common - Possible surface protein, responsible for cell interaction; contains cell adhesion domain and ChW-repeats CAC3273 30 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15894486 Nonpathogen - hypothetical protein CAC1203 1 None None None 15893876 Common - flavodoxin CAC0587 13 COG0716 FldA, Flavodoxins Energy production and conversion 15894513 Nonpathogen - hypothetical protein CAC1230 1 None None None 15893355 Common - hypothetical protein CAC0058 2 None None None 15894975 Common - hypothetical protein CAC1698 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 15896048 Common - Transcriptional regulator, Lrp family (possible nitrite reductase regulator NirD) CAC2793 54 COG1522 Lrp, Transcriptional regulators Transcription 15894667 Common manC Mannose-6-phosphate isomerase CAC1388 49 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 15893430 Nonpathogen - Hypothetical protein, CF-23 family CAC0135 1 None None None 15895682 Common - Uncharacterized protein, ErfK family; contains peptidoglycan-binding domain CAC2416 70 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15894818 Common - Uncharacterized ATP-grasp enzyme CAC1540 76 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 15895812 Common - hypothetical protein CAC2550 17 None None None 15895777 Nonpathogen - hypothetical protein CAC2512 1 None None None 15896399 Common rpmG 50S ribosomal protein L33 CAC3151 93 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 15896042 Common - Serine/threonine protein phosphatase CAC2787 110 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 15894718 Common - hypothetical protein CAC1439 6 None None None 15895741 Common - Uncharacterized protein, homolog of Spirochaeta aurantia (gi:152901) CAC2476 13 COG3070 TfoX, Regulator of competence-specific genes Transcription 15893320 Common asd aspartate-semialdehyde dehydrogenase CAC0022 179 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15894262 Common - Predicted P-loop kinase or ATPase distantly related to phosphoenolpyruvate carboxykinase CAC0975 6 None None None 15895822 Common - Predicted acetyltransferase CAC2560 37 COG0456 RimI, Acetyltransferases General function prediction only 15896477 Common - Predicted phosphatase, HAD superfamily CAC3231 138 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15894589 Nonpathogen - hypothetical protein CAC1307 1 None None None 15894947 Common - Response regulator (CheY-like receiver domain and DNA-binding HTH domain) CAC1670 186 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 15893509 Common - Endoglucanase, aminopeptidase M42 family CAC0216 61 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 15895229 Common - Site-specific recombinases, DNA invertase Pin homolog CAC1956 107 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15896510 Nonpathogen - Predicted membrane protein CAC3265 3 None None None 15894876 Common - Hypothetical protein, CF-32 family CAC1598 3 None None None 15895201 Nonpathogen - hypothetical protein CAC1928 1 None None None 15894103 Common - Lipase-esterase related protein CAC0816 43 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15894525 Common mreB mreB CAC1242 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 15895284 Common - Predicted esterase CAC2014 31 COG0824 FcbC, Predicted thioesterase General function prediction only 15895579 Common - Rhamnosyl transferase, rfbQ CAC2312 161 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15895819 Common - hypothetical protein CAC2557 14 COG4994 COG4994, Uncharacterized protein conserved in bacteria Function unknown 15893437 Nonpathogen - hypothetical protein CAC0142 1 None None None 15895171 Common - Phage-related, Zn finger domain containing protein CAC1897 21 COG1403 McrA, Restriction endonuclease Defense mechanisms 15894256 Common - hypothetical protein CAC0969 1 None None None 15893580 Common - ABC transporter, ATP-binding protein CAC0288 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15894000 Common pgm phosphoglyceromutase CAC0712 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 15895896 Common lonB Lon-like ATP-dependent protease CAC2638 238 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 15893421 Common dnaX DNA polymerase III subunits gamma and tau CAC0125 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15895707 Common - Hemin permease CAC2442 191 COG4139 BtuC, ABC-type cobalamin transport system, permease component Coenzyme metabolism 15896132 Common - ABC-type iron (III) transport system, permease component CAC2878 178 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15893445 Common - hypothetical protein CAC0150 1 None None None 15893628 Common - Hypothetical protein, CF-22 family CAC0336 2 None None None 15896651 Common - HD-GYP domain (HD superfamily hydrolase) CAC3410 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15895753 Common - Uncharacterized conserved protein, YTFE family CAC2488 22 COG3945 COG3945, Uncharacterized conserved protein Function unknown 15893451 Common MltF PTS system, mannitol-specific IIA domain (Ntr-type) (gene MltF) CAC0156 72 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 15896797 Common - HD superfamily hydrolase CAC3562 32 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15893728 Common - Sensory transduction histidine kinase CAC0437 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15895165 Nonpathogen - Phage related protein, possible DNA packing CAC1890 2 None None None 15896102 Common - Ribosome-associated protein Y (PSrp-1) CAC2847 178 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 15896932 Nonpathogen - Hypothetical protein, CF-44 family CAC3701 1 None None None 15895161 Common - Uncharacterized phage related protein CAC1886 5 None None None 15894449 Nonpathogen - hypothetical protein CAC1166 1 None None None 15896748 Common - Membrane associated methyl-accepting chemotaxis protein with HAMP domain CAC3511 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893563 Common - Predicted esterase CAC0271 118 COG0824 FcbC, Predicted thioesterase General function prediction only 15894241 Common - Uncharacterized membrane protein CAC0954 144 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 15894599 Common glpF Glycerol uptake facilitator protein, GLPF CAC1319 110 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 15896403 Common - Uncharacterized conserved protein, THY1 family CAC3155 18 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 15894757 Common rpsD 30S ribosomal protein S4 CAC1478 248 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15896806 Common accB Biotin carboxyl carrier protein of acetyl-CoA carboxylase CAC3572 176 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 15896157 Common - Uncharacterized protein, VEG B.subtilis ortholog CAC2904 17 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 15896050 Common - MoaA/NirJ family Fe-S oxidoreductase CAC2795 188 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 15893506 Nonpathogen - Protein containing LysM motif repeat CAC0213 1 None None None 15894010 Common - Transcriptional regulator, AcrR family CAC0723 17 COG1309 AcrR, Transcriptional regulator Transcription 15893789 Common ftsX Cell division protein (ftsX) CAC0498 132 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 15893606 Common - Uncharacterized protein homolog YKRK B. subtilis CAC0314 9 None None None 15893955 Nonpathogen - Sugar-binding periplasmic protein CAC0667 5 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15893341 Nonpathogen - Hypothetical protein, CF-3 family CAC0043 1 None None None 15893939 Common - hypothetical protein CAC0651 9 None None None 15894796 Common - ABC-type transport system, ATPase component CAC1518 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15895830 Common ganA Predicted arabinogalactan endo-1,4-beta-galactosidase CAC2570 20 COG3867 COG3867, Arabinogalactan endo-1,4-beta-galactosidase Carbohydrate transport and metabolism 15896255 Common thyA thymidylate synthase CAC3003 139 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 15895109 Common - Host factor I protein Hfq CAC1834 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 15893537 Common - ABC transporter ATP-binding protein CAC0245 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15893439 Common sfsa sugar fermentation stimulation protein A CAC0144 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 15894899 Common - Predicted Fe-S oxidoreductase CAC1621 54 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 15893432 Common - Hypothetical protein, CF-5 family CAC0137 2 None None None 15893361 Common - hypothetical protein CAC0064 1 None None None 15895011 Common - Uncharacterized, alkaline shock induced protein CAC1734 31 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 15896676 Common - hypothetical protein CAC3435 2 None None None 15896441 Common - hypothetical protein CAC3193 1 None None None 15895018 Common - Uncharacterized conserved protein, YLBM B.subtilis ortholog CAC1741 26 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 15894909 Common - biotin synthase CAC1631 173 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15895128 Nonpathogen - Predicted membrane protein CAC1853 1 None None None 15896348 Common rpsI 30S ribosomal protein S9 CAC3097 247 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 15893866 Common - Endo-arabinase related enzyme (family 43 glycosyl hydrolase domain and ricin B-like domain) CAC0577 19 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 15894629 Common - hypothetical protein CAC1350 1 None None None 15896817 Common - Predicted permease CAC3583 63 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15893783 Common alr alanine racemase CAC0492 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 15896877 Common - Oligopeptide ABC transporter, permease component CAC3644 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15895982 Common - Predicted hydrolase from alpha/beta family, YQKD B.subtilis ortholog CAC2725 49 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 15896459 Common - Fusion of Uroporphyrinogen-III methylase related protein and MAZG family protein, YABN B.subtilis ortholog CAC3212 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 15895359 Common - Stage III sporulation protein AE, SpoIIIAE CAC2089 15 None None None 15896574 Common - Alanine racemase CAC3331 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 15895567 Common - Uncharacterized secreted protein, YunB B.subtilis homolog CAC2300 14 None None None 15895951 Nonpathogen - Predicted membrane protein CAC2693 1 None None None 15894132 Common - Ferritin-like protein Rsg CAC0845 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 15895390 Common - Predicted enzyme with a TIM-barrel fold CAC2121 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 15896834 Common dapA dihydrodipicolinate synthase CAC3600 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15895856 Nonpathogen - hypothetical protein CAC2597 1 None None None 15895793 Common - Predicted N-acetyltransferase CAC2530 1 COG0456 RimI, Acetyltransferases General function prediction only 15895255 Common - Predicted permease CAC1984 4 COG2510 COG2510, Predicted membrane protein Function unknown 15893924 Common - Signal transduction protein containing diguanilate cyclase/phosphodiesterase domain (GGDEF) CAC0636 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15896621 Common - Uncharacterized protein, YQFW B.subtilis homolog CAC3379 11 COG5663 COG5663, Uncharacterized conserved protein Function unknown 15895805 Common etfA Electron-transferring flavoprotein large subunit CAC2543 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 15896567 Common - Predicted transcriptional regulator CAC3324 47 COG1476 COG1476, Predicted transcriptional regulators Transcription 15896421 Common leuC 3-isopropylmalate dehydratase large subunit CAC3173 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 15896541 Common - D-alanyl-D-alanine carboxypeptidase family hydrolase, YODJ B.subtilis ortholog CAC3297 44 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15895726 Nonpathogen - Hypothetical protein, CF-13 family CAC2461 1 None None None 15896648 Common - Acyl-CoA thioesterase 1 CAC3407 19 COG0657 Aes, Esterase/lipase Lipid metabolism 15896344 Common - Phosphate permease CAC3093 169 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 15895506 Common glgC ADP-glucose pyrophosphorylase CAC2238 121 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 15895365 Common - Aminopeptidase P AMPP/PEPQ family enzyme, YQHT B.subtilis ortholog CAC2095 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15896334 Common - Thioredoxin CAC3083 236 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15896633 Common - NADH-dependent butanol dehydrogenase CAC3392 168 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 15895404 Common - ATP-dependent serine protease LA/LON family CAC2135 165 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 15893636 Nonpathogen - hypothetical protein CAC0345 1 None None None 15893882 Common ribH riboflavin synthase subunit beta CAC0593 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 15895836 Nonpathogen - 6-pyruvoyl-tetrahydropterin synthase related protein CAC2576 6 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15894498 Nonpathogen - hypothetical protein CAC1215 1 None None None 15896946 Common dnaC replicative DNA helicase CAC3715 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15893398 Common - O-acetylhomoserine sulfhydrylase CAC0102 208 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 15894750 Common arbA Ketopantoate reductase CAC1471 7 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 15896280 Common - Conserved membrane protein, possible homolog of CAAX-like membrane endopeptidase CAC3028 33 None None None 15893919 Common - Signal transduction protein containing diguanylate cyclase/phosphodiesterase domain (GGDEF) and domain (EAL) CAC0631 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 15893664 Common - ABC transporter, ATP binding protein CAC0373 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15895728 Nonpathogen - Hypothetical protein, CF-13 family CAC2463 1 None None None 15894494 Nonpathogen - hypothetical protein CAC1211 1 None None None 15896336 Common - TPR-repeat-containing protein; Cell-adhesion domain CAC3085 19 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15893983 Common - altronate oxidoreductase CAC0695 84 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15896548 Common - Hypothetical protein, CF-42 family CAC3304 5 None None None 15893466 Nonpathogen - Predicted membrane protein CAC0172 1 None None None 15895088 Common - Sporulation protein SpoIIIE, DNA segregation ATPase CAC1812 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15895779 Common - Beta galactosidase CAC2514 24 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 15894989 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase CAC1712 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15895376 Nonpathogen - Predicted membrane protein CAC2106 1 None None None 15896605 Common - Uncharacterized conserved membrane protein, YOAK B.subtilis homolog CAC3362 13 COG3619 COG3619, Predicted membrane protein Function unknown 15895622 Common - hypothetical protein CAC2355 14 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 15893459 Common - Predicted ABC transporter, permease component CAC0165 6 None None None 15894358 Common - hypothetical protein CAC1073 10 None None None 15896073 Common - AraC-type DNA-binding domain-containing protein, transcriptional regulator CAC2818 107 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15895335 Common deoB phosphopentomutase CAC2065 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 15896597 Common - Probable cation efflux pump (multidrug resistance protein) CAC3354 173 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15893757 Common - hypothetical protein CAC0466 2 None None None 15894065 Common - ATP-dependent RNA helicase, superfamily II CAC0778 83 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15894812 Common - Predicted permease CAC1534 37 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15895215 Nonpathogen - hypothetical protein CAC1942 1 None None None 15896665 Common - Transcriptional regulator, RpiR family CAC3424 7 COG1737 RpiR, Transcriptional regulators Transcription 15896287 Common - Superfamily I DNA helicase CAC3036 79 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 15895045 Common - Uncharacterized conserved protein, TraB family CAC1768 28 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 15895473 Common fliD Flagellar hook-associated protein FliD CAC2205 27 COG1345 FliD, Flagellar capping protein Cell motility and secretion 15896328 Common - Uncharacterized FAD-dependent dehydrogenase CAC3077 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 15895437 Common - hypothetical protein CAC2168 25 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15894419 Nonpathogen - hypothetical protein CAC1135 1 None None None 15895415 Common flhF flagellar biosynthesis regulator FlhF CAC2146 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 15895044 Nonpathogen - hypothetical protein CAC1767 1 None None None 15894011 Common - Transcriptional regulator, AcrR family CAC0724 23 COG1309 AcrR, Transcriptional regulator Transcription 15895309 Common - Hypothetical protein, CF-5 family CAC2039 4 None None None 15895300 Nonpathogen - hypothetical protein CAC2030 1 None None None 15896237 Common - hypothetical protein CAC2985 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 15893644 Common - 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication) CAC0353 141 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 15894353 Common - TPR-repeat containing protein CAC1067 119 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15893641 Common - hypothetical protein CAC0350 2 None None None 15894769 Common - hypothetical protein CAC1490 1 None None None 15896870 Common - Oligopeptide ABC transporter, ATPase component CAC3636 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15896239 Common - Primase-like protein, containing TOPRIM domain, YABF B.subtilis ortholog CAC2987 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 15893930 Common - Conserved domain seen in the bacterial SpoT CAC0642 50 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 15895430 Common fliG flagellar motor switch protein G CAC2161 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 15896810 Common - Dioxygenase related to 2-nitropropane dioxygenase CAC3576 152 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 15896379 Common rpsS 30S ribosomal protein S19 CAC3129 248 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 15896009 Common - Uncharacterized membrane protein, YPAA B.subtilis ortholog CAC2752 11 COG4684 COG4684, Predicted membrane protein Function unknown 15896730 Common - Predicted transcriptional regulator component, YOBU B.subtilis homolog CAC3493 17 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 15896077 Common - TPR-repeat-containing protein CAC2822 60 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15894111 Common - Thioredoxin CAC0824 6 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15894243 Nonpathogen - hypothetical protein CAC0956 1 COG4980 GvpP, Gas vesicle protein General function prediction only 15895675 Common - Transglutaminase-like enzyme, putative cysteine protease CAC2409 5 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 15896884 Common - Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) CAC3651 176 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 15893820 Common - hypothetical protein CAC0530 4 None None None 15896900 Common - MDR-type permease CAC3668 229 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896618 Common - Possible pectin degradation protein (sugar phosphate isomerase family) CAC3376 39 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 15896713 Common - Transcriptional regulator, merR family CAC3475 124 COG0789 SoxR, Predicted transcriptional regulators Transcription 15893953 Common - ABC-type sugar transport system, permease component CAC0665 156 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 15894795 Common - Membrane associated sensory transduction histidine kinase CAC1517 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15894617 Common - Spore coat protein COTJC CAC1338 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 15893323 Common dcd deoxycytidine triphosphate deaminase CAC0025 89 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 15894447 Nonpathogen - hypothetical protein CAC1164 1 None None None 15895154 Common - Uncharacterized, phage-related protein CAC1879 20 None None None 15896557 Common - Nitroreductase family protein CAC3314 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 15895631 Common - Uncharacterized protein, homolog of gi|2274936 Eubacterium acidaminophilum CAC2364 3 None None None 15894309 Common - Thioesterase II of alpha/beta hydrolase superfamily CAC1022 50 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 15895006 Common - ribosome-associated GTPase CAC1729 164 COG1162 COG1162, Predicted GTPases General function prediction only 15893489 Common - NADH-dependent flavine oxidoreductase CAC0196 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15895143 Common - Uncharacterized secreted protein, homolog YXKC Bacillus subtilis CAC1868 2 None None None 15896480 Common - Uncharacterized conserved protein, YVBJ B.subtilis ortholog with N-terminal C4-type Zn-finger domain CAC3234 9 COG4640 COG4640, Predicted membrane protein Function unknown 15895117 Common - Uncharacterized protein, B.subtilis YTKC ortholog, related to regulatory protein UTXA CAC1842 12 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 15895469 Common - hypothetical protein CAC2201 1 None None None 15894324 Common - Predicted xylanase/chitin deacetylase CAC1037 77 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15893969 Common nrgB Nitrogen regulatory protein PII, gene nrgB CAC0681 184 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15894176 Common - hypothetical protein CAC0889 23 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 15896147 Common - Uncharacterized protein, ywiB B.subtilis homolog CAC2894 14 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 15896304 Common - Histidinol phosphatase related enzyme CAC3053 131 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 15896484 Common - Ucharacterized Fe-S oxidoreductase CAC3238 89 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 15894916 Nonpathogen - Hypothetical protein, CF-37 family(almost identical) CAC1638 1 None None None 15895340 Nonpathogen - hypothetical protein CAC2070 1 None None None 15893693 Nonpathogen - Possible transcriptional regulatory protein, AsnC family CAC0402 1 None None None 15895915 Common - Polyferredoxin CAC2657 20 COG1145 NapF, Ferredoxin Energy production and conversion 15896522 Common nrdA ribonucleotide-diphosphate reductase subunit alpha CAC3277 216 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15896489 Common - Spore cortex-lytic enzyme, pre-pro-form (diverged form of N-acetylmuramyl-L-alanine amidase); peptidoglycan-binding domain CAC3244 3 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 15895548 Common - Predicted membrane protein CAC2280 7 None None None 15894078 Common hfuC Ferrichrome ABC transporter, ATP-binding protein, fhuC CAC0791 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 15894169 Common - Predicted membrane protein, hemolysin III homolog CAC0882 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 15893806 Common - hypothetical protein CAC0515 16 None None None 15893651 Common - Transcriptional regulator, LacI family (HTH lacI domain), B.subtilis degA ortholog CAC0360 129 COG1609 PurR, Transcriptional regulators Transcription 15895495 Common - Phosphoserine phosphatase family enzyme CAC2227 31 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15896761 Nonpathogen - Hypothetical protein, CF-7 family CAC3524 1 None None None 15894367 Nonpathogen - hypothetical protein CAC1082 3 None None None 15893376 Common agrC Histidine kinase-like ATPase CAC0080 34 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 15896780 Common - Membrane associated GGDEF domain containing protein CAC3544 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15895270 Common iorB indolepyruvate oxidoreductase subunit B CAC2000 57 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 15895653 Common - hypothetical protein CAC2387 7 None None None 15896275 Common - hypothetical protein CAC3023 1 None None None 15895062 Common codY transcriptional repressor CodY CAC1786 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 15895865 Common - gluconate 5-dehydrogenase CAC2607 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15893910 Common - polyphosphate kinase CAC0622 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 15894821 Common - Lactate dehydrogenase CAC1543 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15896245 Common - Uncharacterized protein, YceG B.subtilis homolog CAC2993 4 None None None 15893391 Common hemA glutamyl-tRNA reductase CAC0095 179 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 15893687 Common - 3-hexulose-6-phosphate synthase (D-arabino-3-hexulose-6-phosphate formaldehyde lyase) CAC0396 57 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 15896117 Common - Predicted membrane protein CAC2863 1 None None None 15894161 Nonpathogen - Hypothetical protein, CF-36 family CAC0874 1 None None None 15896373 Common rplN 50S ribosomal protein L14 CAC3123 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 15894960 Common - Predicted metal-dependent hydrolase of metallo-beta-lactamase superfamily CAC1683 160 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 15896828 Common - Glycosyltransferase CAC3594 223 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15895550 Common tgt queuine tRNA-ribosyltransferase CAC2282 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 15894630 Common - Periplasmic sugar-binding protein CAC1351 114 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15894681 Common - Unchracterized conserved protein, similar to IcaC of Staphylococcus; YHJR B.subtilis family CAC1402 3 COG3936 COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation Carbohydrate transport and metabolism 15895544 Common - Protein related to N-terminal domain of SS-DNA-specific exonuclease RecJ CAC2276 191 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15894286 Common thrC threonine synthase CAC0999 130 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 15894968 Common - Predicted glycosyltransferase CAC1691 129 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15895709 Common - Predicted metal-binding protein CAC2444 8 COG2158 COG2158, Uncharacterized protein containing a Zn-finger-like domain General function prediction only 15895074 Common - hypothetical protein CAC1798 175 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 15894786 Common - hypothetical protein CAC1508 3 None None None 15893805 Common - CBS domain, similar to B.subtilis ytoI CAC0514 27 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 15893495 Common - Hydrolase of the alpha/beta superfamily CAC0202 32 COG2267 PldB, Lysophospholipase Lipid metabolism 15896804 Common accC biotin carboxylase CAC3570 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 15894615 Nonpathogen - hypothetical protein CAC1336 2 None None None 15895943 Common - Trehalose/maltose hydrolase (phosphorylase) CAC2685 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 15894901 Common - Uncharacterized protein, ortholog of Thermotoga (4980645) CAC1623 21 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 161723226 Common - hydroxylamine reductase CAC2750 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 15894378 Common - Hypothetical secreted protein CAC1093 1 None None None 15895666 Common - Serine/threonine kinase related protein, inactivated (HRDL motif absent) (fragment) CAC2400 3 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 15895973 Common - Predicted glycosyl transferase from UDP-glucuronosyltransferase family CAC2716 35 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 15893472 Common appD Oligopeptide transport ATP-binding protein CAC0179 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15894648 Common hisC Histidinol-phosphate aminotransferase CAC1369 199 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 15895349 Nonpathogen - hypothetical protein CAC2079 1 None None None 15894928 Common - Predicted GTPase with uncharacterized domain, ortholog of T.maritima (4980952) CAC1651 225 COG1160 COG1160, Predicted GTPases General function prediction only 15893308 Common - hypothetical protein CAC0010 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 15894940 Nonpathogen - hypothetical protein CAC1663 1 None None None 15896728 Common - Protein, related to general stress protein 26(GS26) of B.subtilis (pyridoxinephosphate oxidase family) CAC3491 12 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 15894294 Common - Predicted acetyltransferase CAC1007 22 COG0456 RimI, Acetyltransferases General function prediction only 15895574 Common - anti-sigma F factor CAC2307 26 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 15894219 Nonpathogen - hypothetical protein CAC0932 1 COG5583 COG5583, Uncharacterized small protein Function unknown 15896867 Nonpathogen - hypothetical protein CAC3633 1 None None None 15893382 Common - Muconate cycloisomerase related protein, ortholog of YKGB B.subtilis CAC0086 54 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 15894228 Common hisF Imidazoleglycerol-phosphate synthase CAC0941 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 15895220 Common - Phage related transcriptional regulator (Xre family) CAC1947 43 COG1476 COG1476, Predicted transcriptional regulators Transcription 15894092 Common - Methyl-accepting chemotaxis protein CAC0805 160 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894529 Common pbpA Penicillin-binding protein 2 CAC1246 197 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15894144 Common - Glucan phosphorylase CAC0857 142 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 15893559 Common ldh L-lactate dehydrogenase CAC0267 169 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 15893814 Common - Response regulator (CheY-like and HTH domains) CAC0524 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15894707 Nonpathogen - hypothetical protein CAC1428 1 None None None 15893594 Common - Predicted metal-binding protein of ferredoxin fold CAC0302 2 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 15896855 Common fer Ferredoxin CAC3621 34 COG1141 Fer, Ferredoxin Energy production and conversion 15895324 Nonpathogen - hypothetical protein CAC2054 1 None None None 15894095 Common hybG Hydrogenase expression factor (hybG) CAC0808 85 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15894331 Common - NADH:flavin oxidoreductase, possible NADH oxidase CAC1044 188 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15895389 Common - Uncharacterized protein, YlmF B.subtilis ortholog CAC2120 53 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 15895425 Common flgD Flagellar hook assembly protein FlgD CAC2156 74 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 15893624 Common manB Beta-mannanase CAC0332 15 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 15894922 Common - Ankyrin repeats containing protein CAC1645 47 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 15893739 Common feoB Ferrous iron transport protein B (feoB-2) CAC0448 157 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 15896414 Common - Predicted DNA-binding protein CAC3166 29 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 15895225 Common - hypothetical protein CAC1952 6 None None None 15893526 Common - PTS system, fructoso-specific IIBC component CAC0234 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 15893405 Common cysD sulfate adenylyltransferase subunit 2 CAC0109 165 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15894439 Nonpathogen - hypothetical protein CAC1156 1 None None None 15895445 Common - Glycosyltransferase domain containing protein CAC2176 63 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15895843 Common - Uncharacterized conserved membrane protein, YHGE B.subtilis homolog CAC2583 31 COG1511 COG1511, Predicted membrane protein Function unknown 15896267 Common - Glycosyltransferase CAC3015 86 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15896769 Common - hypothetical protein CAC3532 2 None None None 15895058 Common nadE NAD synthetase CAC1782 186 COG0171 NadE, NAD synthase Coenzyme metabolism 15896847 Nonpathogen - hypothetical protein CAC3613 1 None None None 15895271 Common iorA Indolepyruvate ferredoxin oxidoreductase, subunit alpha CAC2001 114 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 15893586 Common - Magnesium and cobalt transporter CAC0294 83 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 15895930 Common - Predicted membrane protein CAC2672 1 None None None 15894724 Nonpathogen - hypothetical protein CAC1445 1 None None None 15895260 Common - ABC-type iron (III) transport system, permease component CAC1990 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15896869 Common - Oligopeptide ABC transporter, ATPase component CAC3635 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 15894412 Nonpathogen - hypothetical protein CAC1128 1 None None None 15895563 Common - Uncharacterized protein, YigZ family CAC2296 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 15895079 Common rbfA ribosome-binding factor A CAC1803 182 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 15895268 Common - ABC-type transport system, ATPase component CAC1998 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15896898 Common - Alpha/beta superfamily hydrolase CAC3665 104 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 15894096 Common hypE Hydrogenase formation factor (hypE) CAC0809 149 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15896862 Common oppF Oligopeptide ABC transporter, ATPase component CAC3628 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 15895945 Common recQ RecQ protein, superfamily II DNA helicase CAC2687 232 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 15896427 Common - Oligopeptide ABC transporter, periplasmic binding component CAC3179 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15896412 Common - Lysine-specific permease CAC3164 155 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 15895869 Nonpathogen - hypothetical protein CAC2611 2 None None None 15895875 Common - Membrane associated methyl-chemotaxis protein, HAMP domain containing CAC2617 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896539 Common - hypothetical protein CAC3294 2 None None None 15894168 Common - hypothetical protein CAC0881 9 None None None 15894410 Nonpathogen - hypothetical protein CAC1126 1 None None None 15894993 Common - hypothetical protein CAC1716 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 15894356 Nonpathogen - Transcriptional regulator, AcrR family CAC1071 1 None None None 15894716 Nonpathogen - Diverged AAA-family ATPase containing protein CAC1437 2 None None None 15893400 Common - adenylylsulfate reductase CAC0104 179 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 15895616 Nonpathogen - hypothetical protein CAC2349 1 None None None 15896623 Common - Membrane protease subunit, stomatin/prohibitin homolog CAC3381 179 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15896060 Common - Possible selenocysteine lyase (aminotransferase of NifS family) CAC2805 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15893408 Common glnQ Glutamine ABC transporter (ATP-binding protein) CAC0112 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15896044 Common - hypothetical protein CAC2789 1 None None None 15894420 Common - Phage related protein, YonJ B.subtilis homolog CAC1136 3 None None None 15893621 Common spoVD Sporulation specific penicillin-binding protein CAC0329 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15894533 Common rodA Cell division protein, rodA/ftsW/spoVE family CAC1251 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15895003 Common - Predicted Fe-S-cluster redox enzyme, YLON B.subtilis ortholog CAC1726 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 15896448 Common - Formate--tetrahydrofolate ligase CAC3201 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 15896808 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CAC3574 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15893582 Common - Sensory transduction histidine kinase CAC0290 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893374 Common agrB putative accessory gene regulator protein CAC0078 11 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 15896241 Common - PHP superfamily hydrolase, YABD ortholog CAC2989 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15894221 Nonpathogen - hypothetical protein CAC0934 2 None None None 15895423 Common flgE Flagellar hook protein FlgE. CAC2154 130 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 15896486 Common - Uncharacterized conserved membrane protein, YYAD B.subtilis ortholog CAC3241 23 COG3949 COG3949, Uncharacterized membrane protein Function unknown 15894967 Common pilT PilT ATPase involved in pili biogenesis CAC1690 165 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 15894912 Common - Flagellin CAC1634 106 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15894310 Common nadC Nicotinate-nucleotide pyrophosphorylase CAC1023 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 15894073 Common - Uncharacterized conserved protein, repeats CAC0786 10 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 15894797 Common - Predicted permease CAC1519 22 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15895655 Common argB Acetylglutamate kinase CAC2389 228 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 15895628 Common infC translation initiation factor IF-3 CAC2361 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 15896714 Common - Methyl-accepting chemotaxis protein CAC3476 160 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894946 Common CstA Carbon starvation protein CAC1669 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 15894835 Common - Predicted acetyltransferase CAC1557 58 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15893604 Common - hypothetical protein CAC0312 1 None None None 15894825 Common trxA Thioredoxin, trx CAC1547 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15894856 Common - Predicted transcriptional regulator CAC1578 21 COG1396 HipB, Predicted transcriptional regulators Transcription 15893823 Common glvA Maltose-6'-phosphate glucosidase (glvA) CAC0533 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 15896299 Common - Uncharacterized conserved membrane protein, possible transporter CAC3048 3 None None None 15896727 Common - DNA gyrase inhibitory protein, GyrI CAC3490 15 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 15896016 Common - Membrane-associated sensory histidine kinase with HAMP domain CAC2760 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15894452 Nonpathogen - hypothetical protein CAC1169 1 None None None 15893386 Common - Xylanase/chitin deacetylase, NodB family CAC0090 86 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15895498 Common - Uncharacterized protein of PR1 family, YkwD B.subtilis ortholog CAC2230 83 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 15895228 Common - hypothetical protein CAC1955 16 COG5515 COG5515, Uncharacterized conserved small protein Function unknown 15895344 Common argR arginine repressor CAC2074 79 COG1438 ArgR, Arginine repressor Transcription 15894927 Common - Hypothetical protein, CF-38 family CAC1650 7 COG5620 COG5620, Uncharacterized conserved protein Function unknown 15894284 Nonpathogen ndk Probable nucleoside-diphosphate kinase N-terminal domain CAC0997 1 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 15894728 Nonpathogen - hypothetical protein CAC1449 1 None None None 15893808 Common pfkA 6-phosphofructokinase CAC0517 159 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 15896845 Common - Regulatory protein related to malT, positive regulator of mal regulon (ATPase and HTH-type DNA-binding domain) CAC3611 51 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 15894576 Common dgkA/pgpB Diacylglycerol kinase (dgkA) fused to phosphatase B domain (pgpB) CAC1294 42 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 15894314 Common - Flavoprotein CAC1027 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15895200 Common - Hypothetical protein, CF-31 family CAC1927 1 None None None 15896046 Common - MoaA/NirJ family Fe-S oxidoreductase CAC2791 93 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 15894417 Nonpathogen - Phage related protein, YonE B.subtilis homolog CAC1133 1 None None None 15893911 Common - hypothetical protein CAC0623 1 None None None 15894459 Nonpathogen - hypothetical protein CAC1176 1 None None None 15894177 Common - hypothetical protein CAC0890 17 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 15894608 Common - Surfactin biosynthesis-related protein, SFP CAC1329 64 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 15894619 Common araR Transcriptional regulator of the LacI family CAC1340 131 COG1609 PurR, Transcriptional regulators Transcription 15895948 Common - Transcriptional regulator, LysR family CAC2690 191 COG0583 LysR, Transcriptional regulator Transcription 15895542 Common spoT RelA/SpoT protein, (p)ppGpp synthetase/pyrophosphohydrolase CAC2274 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 15894910 Common - Endonuclease IV CAC1632 46 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 15896762 Common - Uncharacterized conserved protein, YjeB/RRF2 family CAC3525 168 COG1959 COG1959, Predicted transcriptional regulator Transcription 15894727 Common tetP/tetQ tetracycline resistance protein CAC1448 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15895356 Common - Stage III sporulation protein AH, SpoIIIAH CAC2086 8 None None None 15893680 Nonpathogen - hypothetical protein CAC0389 1 None None None 15895526 Nonpathogen - hypothetical protein CAC2258 1 None None None 15893377 Common agrA Accessory gene regulator protein A CAC0081 38 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 15895224 Common - Site-specific recombinases, DNA invertase Pin homolog CAC1951 130 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15893696 Nonpathogen - hypothetical protein CAC0405 1 None None None 15893394 Common hemD Uroporphyrinogen III syntase CAC0098 206 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 15895120 Common motB Flagellar motor protein MotB CAC1845 151 COG1360 MotB, Flagellar motor protein Cell motility and secretion 15895676 Common recX recombination regulator RecX CAC2410 70 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 15896951 Common - hypothetical protein CAC3720 3 None None None 15895136 Common - Fragment flavodoxin oxidoreductase CAC1861 6 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15896902 Common amyC Sugar permease CAC3670 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 15895360 Common - Stage III sporulation protein AD, SpoIIIAD CAC2090 15 None None None 15894427 Common recD Exodeoxyribonuclease V, Alpha subunit, RecD CAC1143 152 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 15893691 Common - Hypothetical protein, CF-19 family CAC0400 3 None None None 15893818 Common - ABC transporter, ATPase component (two ATPase domains) CAC0528 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15896958 Common - Uncharacterized protein, YYAC B.subtilis homolog CAC3727 14 None None None 15894160 Common xpt xanthine phosphoribosyltransferase CAC0873 26 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15896517 Common - Possible surface protein, responsible for cell interaction; contains cell adhesion domain and ChW-repeats CAC3272 35 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15894683 Common - Transcriptional regulator of sugar metabolism (deoR family) CAC1404 113 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15896162 Common - Spore coat protein cotS related (diverged) CAC2909 2 None None None 15895294 Nonpathogen - Phosphatidylglycerophosphate synthase related protein (fragment) CAC2024 2 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15894172 Common - ferredoxin 3-like protein CAC0885 42 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15893916 Common - Putative Mn transporter, NRAMR family CAC0628 118 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 15895862 Nonpathogen - Predicted membrane protein CAC2603 1 COG4905 COG4905, Predicted membrane protein Function unknown 15895482 Common flgm Regulator of flagellin synthesis, FLGM CAC2214 2 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 15895116 Common - Uncharacterized protein, related to Spore coat protein CotS CAC1841 7 None None None 15894558 Common SpoIIP Stage II sporulation protein P CAC1276 15 None None None 15896739 Common - Transcriptional regulator, fadR family CAC3502 143 COG2188 PhnF, Transcriptional regulators Transcription 15895072 Common - Predicted membrane-associated Zn-dependent protease CAC1796 218 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15894519 Nonpathogen - hypothetical protein CAC1236 1 None None None 15895213 Nonpathogen - hypothetical protein CAC1940 1 None None None 15896246 Common - Toxic anion resistance protein, TELA family, YCEH B.subtilis ortholog CAC2994 35 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 15896964 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CAC3733 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15895416 Common flhA flagellar biosynthesis protein A CAC2147 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 15894610 Common - D-mannonate oxidoreductase CAC1331 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15896857 Common - Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) CAC3623 64 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 15894194 Common - hypothetical protein CAC0907 138 COG0432 COG0432, Uncharacterized conserved protein Function unknown 15895909 Common pyrZ dihydroorotate dehydrogenase electron transfer subunit CAC2651 98 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 15894503 Nonpathogen - hypothetical protein CAC1220 1 None None None 15895804 Common - FAD/FMN-containing dehydrogenase CAC2542 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15896388 Common rpsG 30S ribosomal protein S7 CAC3139 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 15893523 Common - Transcripcional regulator of sugar metabolism CAC0231 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15896124 Common atpE FoF1-type ATP synthase C subunit CAC2870 10 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 15895141 Common - Putative 4-Cys ferredoxin CAC1866 6 None None None 15896839 Common gntP High affinity gluconate/L-idonate permease CAC3605 83 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 15894778 Common - A/G-specific DNA glycosylase CAC1499 228 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 15896590 Common - Amino acid transporter, permease CAC3347 152 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 15894509 Common sigA RNA polymerase sigma factor CAC1226 212 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15895721 Nonpathogen - Hypothetical protein, CF-40 family CAC2456 1 None None None 15893792 Common uppP undecaprenyl pyrophosphate phosphatase CAC0501 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 15894290 Common - Superfamily I DNA helicase (rep-like helicase) CAC1003 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15893984 Common - Putative altronate dehydratase CAC0696 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 15896234 Common - MinD family ATPase (chromosome partitioning) CAC2982 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15893531 Common - Histidine kinase-like ATPase CAC0239 139 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 15895644 Common dapA dihydrodipicolinate synthase CAC2378 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15894766 Common - small acid-soluble spore protein Tlp CAC1487 6 None None None 15895280 Common - Predicted Fe-S oxidoreductase CAC2010 91 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15895551 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase CAC2283 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 15894068 Common - hypothetical protein CAC0781 6 COG4296 COG4296, Uncharacterized protein conserved in bacteria Function unknown 15895321 Nonpathogen - Predicted membrane protein CAC2051 2 None None None 15896128 Common - UDP-N-acetylglucosamine 2-epimerase CAC2874 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 15896599 Common - Lactoylglutathione lyase (LGUL) family protein, diverged CAC3356 3 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 15896035 Nonpathogen - Spore coat protein, cotF related CAC2780 1 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 15896470 Common spoVG regulatory protein SpoVG CAC3223 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 15893966 Common - CBS domains CAC0678 188 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 15895057 Common - Predicted nucleotidyltransferase CAC1781 155 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 15894435 Nonpathogen - hypothetical protein CAC1152 1 None None None 15893397 Common - Methyl-accepting chemotaxis protein CAC0101 16 None None None 15894493 Common dut Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase) CAC1210 176 COG0756 Dut, dUTPase Nucleotide transport and metabolism 15895614 Common - Glycosyltransferase CAC2347 135 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15896140 Common - Uncharacterized conserved protein, predicted metal-dependent enzyme, YQHQ B.subtilis ortholog CAC2886 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 15893661 Common - Cation efflux system protein, AcrB/AcrF/AcrD family CAC0370 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 15895254 Nonpathogen - hypothetical protein CAC1983 1 None None None 15896924 Nonpathogen - hypothetical protein CAC3692 1 None None None 15893551 Common - Fusion nifN/K+nifB (nifN-nitrogenase iron molybdenum cofactor biosinthesis protein, nifK-nitrogenase molibdenum-iron protein beta chain, nifB-nitrogenase iron-molibdenum cofactor biosynthesis protein) CAC0259 66 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15895845 Nonpathogen - 6-pyruvoyl-tetrahydropterin synthase related domain; conserved membrane protein CAC2585 7 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15895669 Common - Predicted membrane protein CAC2403 5 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15893868 Common prkA Serine protein kinase (prkA protein), P-loop containing CAC0579 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 15893862 Common - Predicted membrane protein CAC0572 14 COG4709 COG4709, Predicted membrane protein Function unknown 15893346 Common - Hypothetical protein, CF-17 family CAC0048 2 None None None 15895371 Common - hypothetical protein CAC2101 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 15894462 Nonpathogen - hypothetical protein CAC1179 1 None None None 15896186 Common - Ferredoxin-like domain fused to nitroreductase-like domain CAC2933 56 COG0778 NfnB, Nitroreductase Energy production and conversion 15896942 Nonpathogen - hypothetical protein CAC3711 2 None None None 15896663 Common - Sugar:proton symporter (possible xylulose) CAC3422 74 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15896311 Common - CPSC/CAPB subfamily ATPase CAC3060 157 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15895970 Common - redox-sensing transcriptional repressor Rex CAC2713 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 15896263 Nonpathogen - Predicted membrane protein CAC3011 1 None None None 15895124 Common - Predicted flavoprotein, YhiN family CAC1849 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 15894528 Common pbpA Penicillin-binding protein 2 CAC1245 200 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15896340 Nonpathogen - hypothetical protein CAC3089 1 None None None 15893640 Nonpathogen - Predicted membrane protein CAC0349 1 None None None 15894706 Common gabT 4-aminobutyrate aminotransferase (PLP-dependent) CAC1427 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 15893932 Common gerKA Spore germination protein gerKA CAC0644 15 None None None 15893488 Common - Predicted transcriptional regulator CAC0195 140 COG1733 COG1733, Predicted transcriptional regulators Transcription 15896289 Common ileS isoleucyl-tRNA synthetase CAC3038 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15895245 Nonpathogen - Hypothetical secreted protein CAC1974 2 None None None 15896282 Common hisC histidinol-phosphate aminotransferase CAC3031 229 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 15894200 Common - Possible non-processive endoglucanase family 9, secreted; CelG ortholog; dockerin and cellulose-binding domain CAC0913 14 None None None 15893565 Common - 2-isopropylmalate synthase CAC0273 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15896008 Common - Predicted acetyltransferase CAC2751 19 COG0456 RimI, Acetyltransferases General function prediction only 15894953 Common - hypothetical protein CAC1676 4 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 15895024 Common acpA Acyl carrier protein, ACP CAC1747 190 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15896873 Common - CRO repressor-like DNA-binding protein CAC3639 4 None None None 15894207 Nonpathogen - Protein related to MIFH/DOPD protein family, function in bacteria is unknown CAC0920 10 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 15896178 Common - HD superfamily hydrolase CAC2925 6 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 15894907 Common - Putative intracellular protease/amidase, ThiJ family CAC1629 164 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15896072 Nonpathogen - Predicted membrane protein CAC2817 1 None None None 15895884 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CAC2626 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15896540 Common - Probable cation efflux pump (multidrug resistance protein) CAC3295 102 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15896524 Common - Possible surface protein, responsible for cell interaction; contains cell adhesion domain and ChW-repeats CAC3279 35 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15896610 Nonpathogen - Protein distantly similar to N-terminal fragment of HSP60 chaperonin family CAC3367 1 None None None 15893861 Common - Predicted transcriptional regulator CAC0571 71 COG1695 COG1695, Predicted transcriptional regulators Transcription 15895983 Common - Uncharacterized protein, possible ynzC B.subtilis homolog CAC2726 12 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 15895050 Common sacB2 Levansucrase CAC1774 16 None None None 15895988 Common - Predicted permease CAC2731 31 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15895857 Common - Uncharacterized protein, homolog of ywsA B.subtilis CAC2598 2 None None None 15894366 Common - Uncharacterized protein, probably surface-located CAC1081 12 COG4676 COG4676, Uncharacterized protein conserved in bacteria Function unknown 15895795 Common - Protein containing ChW-repeats CAC2532 7 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15895833 Common - Predicted S-adenosylmethionine-dependent methyltransferase CAC2573 29 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15893443 Common - Predicted enzyme with TIM-barrel fold CAC0148 8 None None None 15893637 Nonpathogen - hypothetical protein CAC0346 1 None None None 15896831 Common - Rubrerythrin CAC3597 28 COG1592 COG1592, Rubrerythrin Energy production and conversion 15894124 Common potD Spermidine/putrescine-binding periplasmic protein CAC0837 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15894470 Nonpathogen - hypothetical protein CAC1187 1 None None None 15896452 Common spoIIE Stage II sporulation protein E, serine phosphatase family CAC3205 31 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 15896617 Common - Alcohol dehydrogenase CAC3375 191 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15895362 Common - stage III sporulation protein SpoAB CAC2092 13 None None None 15895066 Common frr ribosome recycling factor CAC1790 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 15893934 Common leuS leucyl-tRNA synthetase CAC0646 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15894023 Common - Possible glucanotransferase (putative endo alpha-1,4 polygalactosaminidase related protein) CAC0736 15 COG3868 COG3868, Uncharacterized conserved protein Function unknown 15895111 Common mutL DNA mismatch repair protein CAC1836 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 15894329 Nonpathogen - Predicted membrane protein CAC1042 1 None None None 15894695 Common - Predicted acetyltransferase CAC1416 76 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15893538 Common - Conserved membrane protein, predicted permease CAC0246 20 COG0730 COG0730, Predicted permeases General function prediction only 15893994 Common - Endo-1,4-beta glucanase (fused to two ricin-B-like domains) CAC0706 19 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 15895405 Common - hypothetical protein CAC2136 1 None None None 15894320 Common - Hypothetical protein, CF-31 family CAC1033 1 None None None 15893544 Common - Molybdate-binding protein CAC0252 58 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 15895953 Nonpathogen - Diverged Metallo-dependent hydrolase(Zn) of DD-Peptidase family; peptodoglycan-binding domain CAC2695 1 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 15894368 Common - Predicted membrane-associated metal-binding protein CAC1083 7 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 15894698 Common - Uncharacterized proteins, homologs of microcin C7 resistance protein MccF CAC1419 67 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 15893589 Common - Lysine decarboxylase CAC0297 92 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 15893755 Common - Protein, related to divalent cations, tolerance CutA family CAC0464 54 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 15895684 Common - hypothetical protein CAC2418 2 None None None 15895503 Common cysK Cysteine synthase/cystathionine beta-synthase, CysK CAC2235 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 15894647 Common cbiO Cobalt transport (ATPase component) CAC1368 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15894348 Nonpathogen - hypothetical protein CAC1062 1 None None None 15896564 Common - hypothetical protein CAC3321 16 None None None 15894308 Common - Predicted Fe-S oxidoreductase CAC1021 104 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15895717 Common - flavodoxin CAC2452 49 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15893492 Nonpathogen - hypothetical protein CAC0199 1 None None None 15896673 Common - Alpha/beta superfamily hydrolase CAC3432 28 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15895590 Common - Predicted membrane protein CAC2323 3 None None None 15896607 Nonpathogen - Barstar-like protein, ribonuclease (barnase) inhibitor CAC3364 3 None None None 15896755 Common - Transcriptional regulators, AcrR family CAC3518 22 COG1309 AcrR, Transcriptional regulator Transcription 15896217 Common lacE PTS system lactose-specific enzyme IIBC CAC2964 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 15893456 Common - ABC transporter (permease) CAC0161 76 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 15894816 Common - Predicted permease, YCXC B.subtilis ortholog CAC1538 131 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 15895103 Common - TldD-like protein fragment CAC1827 2 None None None 15896498 Common proB gamma-glutamyl kinase CAC3253 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 15895934 Common - Predicted pseudouridylate synthase CAC2676 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15894113 Common - Endoglucanase family 5 CAC0826 14 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 15894686 Common - PTS system, beta-glucosides-specific IIABC component CAC1407 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15893753 Common - Protein of short-chain alcohol dehydrogenase family CAC0462 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 15896019 Common - Membrane assosiated methyl-accepting chemotaxis protein with HAMP domain CAC2763 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896367 Common rplR 50S ribosomal protein L18 CAC3117 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 15894585 Common - Uncharacterized protein of YbgI/Acr family CAC1303 142 COG0327 COG0327, Uncharacterized conserved protein Function unknown 15896895 Common - Membrane associated sensory histidine kinase CAC3662 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15894475 Nonpathogen - Phage replicative DNA helicase, YorI B.subtilis homolog CAC1192 2 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15895607 Common mutS1 recombination and DNA strand exchange inhibitor protein CAC2340 203 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15895168 Common - Phage-related, head portal protein CAC1894 37 COG4695 COG4695, Phage-related protein Function unknown 15895818 Common - Endoglucanase, family 26; S-layer homology domain CAC2556 31 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 15896098 Common - Protein containing aminopeptidase domain (iap family) CAC2843 48 COG2234 Iap, Predicted aminopeptidases General function prediction only 15895747 Common - Carbonic anhydrase CAC2482 156 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 15894148 Common - ABC-type multidrug transport system, ATPase component CAC0861 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15895387 Common - Cell division protein DivIVA CAC2118 41 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 15893501 Common - Predicted membrane protein; CF-20 family CAC0208 1 None None None 15894138 Common - Ortholog ygiD E.coli CAC0851 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 15896112 Common mreV Shape-determining protein envB (HSP70 family charepones) CAC2858 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 15896151 Common spoIIR Stage II sporulation protein R CAC2898 15 None None None 15896226 Common kdgA keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase CAC2973 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 15895975 Common - Ethanolamine ammonia lyase large subunit CAC2718 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 15893553 Common nifV Homocitrate synthase,alpha subunit nifV(nioA) CAC0261 199 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15894217 Common metB Cystathionine gamma-synthase CAC0930 208 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15896101 Common secA preprotein translocase subunit SecA CAC2846 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 15894238 Common - Ferric uptake regulation protein CAC0951 172 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15895170 Common - Phage terminase-like protein, small subunit CAC1896 21 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 15896450 Common hprT Hypoxanthine-guanine phosphoribosyltransferase CAC3203 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 15895820 Nonpathogen - hypothetical protein CAC2558 4 None None None 15894871 Common - Zn-binding lipoprotein related (surface adhesin A), ADHS CAC1593 174 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15894885 Common - hypothetical protein CAC1607 2 None None None 15894261 Common argH Argininosuccinate lyase CAC0974 229 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 15895763 Common - Carbon monoxide dehydrogenase, catalytic subunit (cooS) CAC2498 36 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 15894276 Nonpathogen - General secretion family related protein CAC0989 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 15893891 Common ftsH ATP-dependent zinc metallopeptidase FtsH (cell dividion protein) CAC0602 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15895573 Common - sporulation sigma factor SigF CAC2306 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15896135 Common - Protein-tyrosine-phosphatase, YWLE B.subtilis ortholog CAC2881 57 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 15894013 Common - Ribose 5-phosphate isomerase RpiB CAC0726 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 15893668 Common - Amino acid (glutamine) ABC transporter, permease component CAC0377 170 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15893898 Common - Cyclic beta 1-2 glucan synthetase CAC0609 47 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 15894399 Nonpathogen - hypothetical protein CAC1114 1 None None None 15894444 Common - Predicted ATPase of HSP70 class CAC1161 2 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15895534 Common - Uncharacterized conserved membrane protein (fragment) CAC2266 17 COG3610 COG3610, Uncharacterized conserved protein Function unknown 15896554 Common - TPR-repeat domain fused to glycosyltransferase CAC3311 18 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15894205 Nonpathogen - Possible non-processive endoglucanase family 5, ortholog of mannase A, secreted; dockerin domain CAC0918 5 None None None 15896661 Common - Low specificity L-threonine aldolase CAC3420 66 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 15896944 Common - Uncharacterized conserved protein, yukE/yfjA B.subtilis family CAC3713 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15894035 Common - Nitroreductase family protein CAC0748 5 None None None 15896384 Common rpsJ 30S ribosomal protein S10 CAC3134 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 15894382 Common - hypothetical protein CAC1097 3 None None None 15894764 Common - Glycosyltransferase, involved in cell wall biogenesis CAC1485 129 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894735 Common - Sugar-binding periplasmic protein CAC1456 41 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15895893 Common - hypothetical protein CAC2635 1 None None None 15896922 Common - Uncharacterized conserved protein, related to polyketide cyclase (CypC) CAC3690 16 COG3832 COG3832, Uncharacterized conserved protein Function unknown 15893321 Common - Transcriptional regulator, LysR family CAC0023 193 COG0583 LysR, Transcriptional regulator Transcription 15896692 Common - Sugar/Na+(H+) simporter CAC3451 80 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15893774 Common - Conserved membrane protein, possible homolog of CAAX-like membrane endopeptidase CAC0483 19 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 15895148 Nonpathogen - hypothetical protein CAC1873 1 None None None 15896058 Common - Membrane associated methyl-accepting chemotaxis protein CAC2803 167 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893524 Common fruB 1-phosphofructokinase (fructoso 1-phosphate kinase) CAC0232 126 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 15896681 Nonpathogen - hypothetical protein CAC3440 1 None None None 15895867 Common - hypothetical protein CAC2609 51 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 15893486 Common - Uncharacterized conserved membrane protein, affecting LPS biosynthesis CAC0193 28 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 15893549 Common nifK Nitrogenase molibdenum-iron protein, beta chain, gene nifK CAC0257 52 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15896437 Common clpC ATPase with chaperone activity clpC, two ATP-binding domain CAC3189 245 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15896228 Nonpathogen - hypothetical protein CAC2975 1 None None None 15895886 Common - Predicted metal-dependent peptidase CAC2628 104 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 15894505 Common - DNA-methyltransferase (cytosine-specific) CAC1222 112 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15896250 Common - TPR-repeat-containing protein CAC2998 155 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15896743 Common - Predicted MDR-type permease CAC3506 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896306 Common - Sugar kinase CAC3055 46 COG2605 COG2605, Predicted kinase related to galactokinase and mevalonate kinase General function prediction only 15896911 Nonpathogen kdpX Uncharacterized protein of kdp operon, kdpX CAC3679 1 None None None 15895036 Common rplS 50S ribosomal protein L19 CAC1759 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 15894879 Common - Methyl-accepting chemotaxis-like protein (chemotaxis sensory transducer) CAC1601 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894834 Common - Chitinase family protein CAC1556 42 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 15894185 Common aroK Shikimate kinase CAC0898 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 15894859 Common - Response regulator (CheY-like receiver domain and HTH DNA-binding domain) CAC1581 122 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 15896396 Common rplK 50S ribosomal protein L11 CAC3148 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 15893922 Common - Predicted membrane protein CAC0634 15 COG4720 COG4720, Predicted membrane protein Function unknown 15895460 Common - Lactoylglutathione lyase, YQJC B.subtilis ortholog CAC2192 31 None None None 15894371 Common xylR Transcriptional regulators of NagC/XylR family CAC1086 131 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15895636 Nonpathogen - hypothetical protein CAC2369 1 None None None 15894004 Common smpB SsrA-binding protein CAC0716 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 15894586 Common - Uncharacterized conserved protein, predicted metal-binding CAC1304 3 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 15895700 Common - Response regulator (CheY-like domain and HTH-type DNA-binding domain) CAC2435 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15893449 Common MtlA PTS system, mannitol-specific IIBC component (gene MtlA) CAC0154 42 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 15895286 Common fadB Enoyl-CoA hydratase CAC2016 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 15894895 Common - hypothetical protein CAC1617 3 None None None 15896149 Common - Uncharacterized protein, YPEB B.subtilis ortholog CAC2896 14 None None None 15896919 Common - Transcriptional regulator, AcrR family CAC3687 117 COG1309 AcrR, Transcriptional regulator Transcription 15893317 Common - Transcriptional regulator, AcrR family CAC0019 94 COG1309 AcrR, Transcriptional regulator Transcription 15896392 Common rpoB DNA-directed RNA polymerase subunit beta CAC3143 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 15893357 Nonpathogen - Predicted membrane protein CAC0060 1 None None None 15896585 Common - Dehydrogenase related to 3-hydroxyisobutyrate dehydrogenase, YKWC B.subtilis ortholog CAC3342 194 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 15894865 Common - Integral membrane protein possibly involved in chromosome condensation CAC1587 150 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 15893879 Common ribD Riboflavin biosynthesis protein RIBD (pirimidine deaminase and pirimidine reductase) CAC0590 235 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 15896704 Common - Amidase from nicotinamidase family CAC3465 101 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 15895900 Common - Predicted endonuclease CAC2642 9 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 15896332 Common - Spore-cortex-lytic enzyme, SLEB CAC3081 30 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 15895790 Nonpathogen - 6-pyruvoyl-tetrahydropterin synthase related protein CAC2526 12 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15895788 Nonpathogen - hypothetical protein CAC2524 4 COG4083 COG4083, Predicted membrane protein Function unknown 15896657 Common - Uncharacterized protein, homolog of YYBI B.subtilis fused to uncharacterized domain similar to A.thaliana (gi:3292817 and 5002526) CAC3416 3 None None None 15896054 Common - Uncharacterized conserved protein, similar to lppY/lpqO of M.tuberculosis CAC2799 12 None None None 15896826 Common - Hypothetical protein, CF-27 family CAC3592 16 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 15893724 Common - Methyl-accepting chemotaxis protein CAC0433 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894622 Common - putative phosphoketolase CAC1343 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 15896096 Common - Conserved membrane protein, probable transporter, YPAA B.subtilis ortholog CAC2841 21 COG3601 COG3601, Predicted membrane protein Function unknown 15894593 Nonpathogen - hypothetical protein CAC1313 1 None None None 15893706 Common - TPR-repeat-containing protein CAC0415 130 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15894632 Common - Phosphotransferase system IIC component, possibly N-acetylglucosamine-specific CAC1353 50 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15894088 Common - phosphoenolpyruvate synthase CAC0801 185 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15895230 Common - Predicted aldo/keto reductase, YTBE/YVGN B.subtilis ortholog CAC1958 199 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 15894854 Common - Predicted oxidoreductase, ortholog of GSP39 B.subtilis CAC1576 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15894106 Common - phosphoribosylpyrophosphate synthetase CAC0819 233 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15895301 Common - hypothetical protein CAC2031 3 None None None 15895872 Common - Beta-phosphoglucomutase CAC2614 192 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15895134 Common - hypothetical protein CAC1859 4 None None None 15894892 Common - Predicted glycosyltransferase CAC1614 6 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15895313 Nonpathogen - hypothetical protein CAC2043 1 None None None 15895468 Common - hypothetical protein CAC2200 21 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15893575 Common - Molybdopterin biosynthesis protein CAC0283 179 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 15895026 Common - BioB/LipA-like protein CAC1749 144 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 15895860 Common - S-adenosylmethionine decarboxylase CAC2601 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 15893670 Common - Transcriptional regulator, GntR family CAC0379 135 COG1802 GntR, Transcriptional regulators Transcription 15893848 Common - hypothetical protein CAC0558 1 None None None 15894882 Common mgsA methylglyoxal synthase CAC1604 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 15895578 Common - Nitroreductase family protein CAC2311 94 COG0778 NfnB, Nitroreductase Energy production and conversion 15893959 Common - Ortholog yrbG, yetE, ykjA, ydfS, ydfR B.subtilis CAC0671 67 COG2323 COG2323, Predicted membrane protein Function unknown 15893943 Nonpathogen - Hypothetical protein, CF-26 family CAC0655 1 None None None 15893841 Common - Uncharacterized protein with possible cell attachment and effacing function; Cell-adhesion domain CAC0551 10 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15893543 Nonpathogen - Uncharacterized Fe-S protein (fragment) CAC0251 1 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 15895964 Common - 8-oxoguanine-DNA-glycosylase CAC2707 29 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 15894949 Common - Rad3-related DNA helicase CAC1672 97 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 15895183 Common rnd Ribonuclease D CAC1909 87 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 15895237 Common greA Transcription elongation factor GreA CAC1965 137 COG0782 GreA, Transcription elongation factor Transcription 15895939 Common - hypothetical protein CAC2681 1 None None None 15896641 Common - Predicted dehydrogenase CAC3400 170 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15895093 Common - Stage V sporulation protein, spoVS CAC1817 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 15896502 Nonpathogen - Predicted membrane protein CAC3257 1 None None None 15894932 Common purQ/purL bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) CAC1655 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 15895306 Common - hypothetical protein CAC2036 2 None None None 15894018 Common - FUSION: Nucleoside-diphosphate-sugar epimerase and GAF domain CAC0731 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15896468 Common prs Phosphoribosylpyrophosphate synthetase CAC3221 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15893513 Common - Aspartate aminotransferase CAC0221 151 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 15893887 Common gerKC Spore germination protein, gerKC CAC0598 12 None None None 15895475 Common - hypothetical protein CAC2207 1 None None None 15893615 Common - Sensory transduction histidine kinase CAC0323 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893929 Common - hypothetical protein CAC0641 16 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 15894195 Common - Dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis family 1 CAC0908 223 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 15893415 Common cheW Chemotaxis protein cheW CAC0119 114 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15896787 Common natA Na+ ABC transporter (ATP-binding protein), NATA CAC3551 249 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 15894986 Common phoU Phosphate uptake regulator CAC1709 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 15895516 Nonpathogen - hypothetical protein CAC2248 1 None None None 15895991 Common - ABC-type multidrug transport system, ATPase component CAC2734 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15895277 Common - Predicted glycosyltransferase CAC2007 10 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 15894152 Common - Two-component response regulator CAC0865 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15893764 Common dnaK DnaK protein (heat shock protein), C-terminal region has VWA type A domain CAC0473 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15893609 Common - Sensory transduction histidine kinase CAC0317 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15894054 Common - Fe-S oxidoreductase CAC0767 94 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 15894747 Common - Predicted acetyltransferase CAC1468 47 COG0456 RimI, Acetyltransferases General function prediction only 15894669 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit CAC1390 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 15893429 Common - Hypothetical protein, CF-19 family CAC0134 3 None None None 15895380 Common - Fibronectin-binding protein CAC2111 87 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 15894270 Common - hypothetical protein CAC0983 1 None None None 15893711 Common - Conserved membrane protein, possible homolog of CAAX-like membrane endopeptidase CAC0420 39 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 15894537 Common - hypothetical protein CAC1255 42 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 15895292 Common moaB Molybdopterin biosynthesis enzyme, moaB CAC2022 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 15893977 Common ntH Predicted endonuclease, gene nth CAC0689 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 15896183 Common - hypothetical protein CAC2930 70 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15895322 Common - DNA-dependent RNA polymerase sigma subunit CAC2052 208 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15894212 Common - TPR-repeat-containing protein CAC0925 99 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15896338 Common - Phosphoenolpyruvate-protein kinase (PTS system enzyme I) CAC3087 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 15893834 Common - Permease CAC0544 8 None None None 15895414 Common - ATPase involved in chromosome partitioning, MinD family, YLXH B.subtilis ortholog CAC2145 209 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15895752 Common - Predicted acetyltransferase CAC2487 26 COG3981 COG3981, Predicted acetyltransferase General function prediction only 15896297 Common - Transcriptional regulator, LytR family CAC3046 61 COG1316 LytR, Transcriptional regulator Transcription 15894655 Common cbiC precorrin-8X methylmutase CAC1376 103 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 15895668 Common - TPR repeats containing protein CAC2402 23 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15894847 Common - Transcriptional regulators, MarR/EmrR family CAC1569 110 COG1846 MarR, Transcriptional regulators Transcription 15895733 Common - Predicted acetyltransferase CAC2468 35 COG3153 COG3153, Predicted acetyltransferase General function prediction only 15895174 Nonpathogen - Phage regulatory Com-like protein, containing Zn-finger CAC1900 1 COG4416 Com, Mu-like prophage protein Com General function prediction only 15894715 Nonpathogen - hypothetical protein CAC1436 5 None None None 15894545 Common - HD superfamily hydrolase, yqeK B.subtilis ortholog CAC1263 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 15894487 Nonpathogen - hypothetical protein CAC1204 1 None None None 15896794 Common - Uncharacterized conserved membrane protein, YHBJ B.subtilis (possible permease)ortholog CAC3559 10 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15895580 Common - Glycosyltransferase CAC2313 68 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15894930 Common - Predicted glycosyltransferase involved in cell wall biogenesis CAC1653 204 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894408 Common - hypothetical protein CAC1124 8 None None None 15896519 Common - Possible surface protein, responsible for cell interaction; contains cell adhesion domain and ChW-repeats CAC3274 33 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15896537 Common - NifU homolog involved in Fe-S cluster formation CAC3292 162 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 15894019 Common - Predicted membrane protein CAC0732 5 None None None 15896159 Common - Spore coat protein cotS related CAC2906 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 15895010 Common rpmB Ribosomal protein L28 CAC1733 59 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 15896404 Common - Uncharacterized conserved protein, YACZ B.subtilis ortholog CAC3156 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 15896934 Nonpathogen - hypothetical protein CAC3703 1 None None None 15893368 Common - Uncharacterized conserved protein, YTFE E.coli ortholog CAC0071 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 15894392 Nonpathogen - Hypothetical protein, CF-36 family CAC1107 1 None None None 15894596 Nonpathogen - Predicted membrane protein CAC1316 1 None None None 15894974 Common - Uncharacterized conserved protein, YMXH B.subtilis homolog CAC1697 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 15896770 Common - Site-specific modification DNA-methyltransferase CAC3534 24 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 15893508 Common - Endoglucanase, aminopeptidase M42 family CAC0215 88 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 15896659 Common - Transcriptional regulator, MarR/EmrR family CAC3418 21 COG1846 MarR, Transcriptional regulators Transcription 15893312 Common - Aminotransferase CAC0014 176 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 15896685 Common - Probable cation efflux pump (multidrug resistance protein) CAC3444 179 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15896632 Common - Membrane associated signal transduction histidine kinase CAC3391 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15894772 Common - Zn-finger DNA-binding domain CAC1493 11 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 15895459 Common spsF Spore coat polysaccharide biosynthesis protein F CAC2190 70 COG1861 SpsF, Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog Cell envelope biogenesis, outer membrane 15895731 Common - Predicted aldoketomutase of glyoxalase I family CAC2466 13 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 15895696 Common - Alkaline phosphatase superfamily enzyme CAC2431 70 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15895873 Common - Uncharacterized conserved protein, CotF B.subtilis family CAC2615 4 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 15893904 Nonpathogen - Predicted membrane protein CAC0616 1 None None None 15894842 Common - Closely related to alginate O-acetylation protein (algI) CAC1564 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 15893344 Nonpathogen - Hypothetical protein, CF-2 family CAC0046 1 None None None 15894567 Common - Uncharacterized conserved protein, ortholog of YQEU B.subtilis CAC1285 188 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 15893825 Common - Metal-dependent hydrolase of the beta-lactamase superfamily II CAC0535 59 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 15893884 Common - Glutamine amidotranspherase (possibly involved in histidine and purine biosinthesis) CAC0595 90 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 15894454 Nonpathogen - hypothetical protein CAC1171 1 COG5306 COG5306, Uncharacterized conserved protein Function unknown 15895998 Common gpmA Phosphoglycerate mutase CAC2741 164 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 15895738 Common - Predicted transcriptional regulator CAC2473 56 COG1476 COG1476, Predicted transcriptional regulators Transcription 15894316 Common - FeoA-like protein, involved in iron transport CAC1029 57 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 15895528 Common - Spore coat polysaccharide biosynthesis protein, Pyridoxal-dependent enzyme CAC2260 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15896375 Common rpmC Ribosomal protein L29 CAC3125 175 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 15896568 Common - Periplasmic amino acid binding protein CAC3325 186 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15896953 Common rpsR 30S ribosomal protein S18 CAC3722 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 15894216 Common - SAM-dependent methyltransferase CAC0929 164 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15895146 Common - FtsK-like DNA segregation ATPase, YDCQ B.subtilis ortholog CAC1871 194 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15896800 Nonpathogen - Uncharacterized secreted protein, containing cell adhesion domain CAC3565 1 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15896261 Common - Xylanase/chitin deacetylase family protein CAC3009 83 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15893813 Common - SAM-dependent methyltransferase related to tRNA(uracyl-5-)-methyltransferase (trmA family) CAC0523 208 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 15894799 Common - Uncharacterized membrane protein, yetF/ydfS/ykjA/yrbG/ydfR B.subtilis ortholog CAC1521 59 COG2323 COG2323, Predicted membrane protein Function unknown 15896061 Common - Predicted phosphohydrolase, Icc family CAC2806 8 COG1409 Icc, Predicted phosphohydrolases General function prediction only 15896577 Common - Multimeric flavodoxin WrbA family protein CAC3334 47 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15894282 Nonpathogen - Predicted membrane protein CAC0995 1 None None None 15893744 Common - ABC-transporter, ATP-binding protein CAC0453 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15896546 Common gerKC Spore germination protein GerKC, membrane protein CAC3302 15 None None None 15894642 Common sodC Superoxide dismutase, Cu-Zn family CAC1363 83 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 15896086 Common - Conserved membrane protein, YccA family CAC2831 123 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 15893936 Common - Molecular chaperone, DnaJ family (contain C-term. Zn finger domain) CAC0648 225 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15895248 Nonpathogen - Predicted membrane protein CAC1977 1 None None None 15896322 Common - Glycosyltransferase CAC3071 159 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15895554 Common - Uncharacterized protein, similar to protein from Clostridium histolyticum (GI:3892648) CAC2286 1 None None None 15896904 Common msmE ABC-type sugar transport system, periplasmic sugar-binding component CAC3672 8 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15895484 Common FliM Flagellar switch protein FliM CAC2216 107 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 15895222 Nonpathogen - Possible TPR-repeat contaning protein CAC1949 1 None None None 15895151 Common lyc N-acetylmuramidase, autolytic enzyme, family 25 of glycosyl hydrolase ; peptodoglycan-binding domain CAC1876 43 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 15894179 Common - 3-deoxy-7-phosphoheptulonate synthase CAC0892 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 15894606 Common - Uncharacterized protein homolog T.maritima (4980675) CAC1326 5 None None None 15894979 Nonpathogen - hypothetical protein CAC1702 1 None None None 15894612 Common - AraC-type sugar metabolism regulator CAC1333 130 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15895354 Common nusB transcription antitermination protein NusB CAC2084 116 COG0781 NusB, Transcription termination factor Transcription 15895597 Common - Sugar transferase involved in lipopolysaccharide synthesis CAC2330 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 15895339 Nonpathogen - hypothetical protein CAC2069 1 None None None 15893433 Common - ABC transporter, ATP-binding component CAC0138 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15893392 Common hemW precorrin-2 dehydrogenase CAC0096 35 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 15896816 Common - hypothetical protein CAC3582 1 None None None 15896106 Common comFC Predicted amidophosphoribosyltransferase, ComFC B.suntilis ortholog CAC2852 136 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 15893889 Common - Predicted membrane protein CAC0600 5 COG4194 COG4194, Predicted membrane protein General function prediction only 15893801 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CAC0510 212 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 15893914 Common trpS tryptophanyl-tRNA synthetase CAC0626 235 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15895892 Common - Ferric uptake regulator (FUR family), YGAG B.subtilis ortholog CAC2634 200 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15896514 Common - ABC-type MDR transport system, ATPase component CAC3269 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15895347 Common - 1-deoxy-D-xylulose-5-phosphate synthase CAC2077 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 161723224 Common aspC aspartyl-tRNA synthetase CAC3564 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15895966 Common etfA Electron transfer flavoprotein alpha-subunit CAC2709 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 15895719 Nonpathogen - Hypothetical protein, CF-13 family CAC2454 1 None None None 15893381 Nonpathogen - hypothetical protein CAC0085 1 None None None 15893309 Common - Uncharacterized conserved of ErfK family CAC0011 1 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15896274 Common - Alpha/beta superfamily hydrolase CAC3022 8 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 15895840 Nonpathogen - Hypothetical protein, CF-41 family CAC2580 2 None None None 15896764 Common - Ferredoxin CAC3527 41 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15896023 Common - Transcriptional regulators, AcrR family CAC2768 84 COG1309 AcrR, Transcriptional regulator Transcription 15895864 Common - hypothetical protein CAC2606 24 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 15895114 Nonpathogen - hypothetical protein CAC1839 1 None None None 15896122 Common atpH F0F1 ATP synthase subunit delta CAC2868 76 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 15896473 Common - Predicted membrane protein CAC3226 1 None None None 15896859 Common - Fe-S oxidoreductase of MoaA family CAC3625 168 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 15894789 Common - FNR-like catabolite gene activator (c-AMP binding domain) CAC1511 81 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15896212 Common galK galactokinase CAC2959 99 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 15896864 Common oppC Oligopeptide ABC transporter, permease component CAC3630 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15893533 Common - ABC-type multidrug transport system, ATP-ase compoment CAC0241 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15896368 Common rplF 50S ribosomal protein L6 CAC3118 236 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 15893402 Common - ABC-type probable sulfate transporter, periplasmic binding protein CAC0106 111 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 15895931 Common ligA NAD-dependent DNA ligase LigA CAC2673 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15896609 Nonpathogen - hypothetical protein CAC3366 1 None None None 15896331 Common - hypothetical protein CAC3080 2 None None None 15896243 Common metG methionyl-tRNA synthetase CAC2991 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15896625 Common - Protein chain release factor B CAC3384 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 15894569 Common - HIT family hydrolase CAC1287 240 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15896446 Common - NifR3 family enzyme CAC3199 219 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15895333 Common dacF D-alanyl-D-alanine carboxypeptidase CAC2063 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15895001 Common - Predicted metal-dependent peptidase CAC1724 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 15894995 Common gmk guanylate kinase CAC1718 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 15895710 Common - 5-aminoimidazole-4-carboxamide ribonucleotide transformylase CAC2445 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 15895941 Nonpathogen cotF Related to spore coat protein F CAC2683 2 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 15893592 Common - DNA polymerase III subunit delta' CAC0300 241 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15895877 Common - Acyl-CoA thioesterase family protein CAC2619 5 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 15895980 Common - dipeptidase PepV CAC2723 179 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15894223 Common hisG ATP phosphoribosyltransferase catalytic subunit CAC0936 213 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 15896938 Common - Uncharacterized protein, homolog of Bacillus firmus (gi:2654481) CAC3707 8 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 15896886 Nonpathogen - hypothetical protein CAC3653 1 None None None 15894914 Common - Uncharacterized protein, homolog of B. firmus (2654481) CAC1636 8 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 15896194 Common - HAD superfamily hydrolase CAC2941 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15896168 Common panC Pantoate--beta-alanine ligase CAC2915 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 15894649 Common cbiG cobalamin biosynthesis protein CbiG CAC1370 82 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 15895540 Common - Predicted Zn-dependent hydrolase of metallo-beta-lactamase superfamily CAC2272 225 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15895918 Common pykA pyruvate carboxylase CAC2660 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 15896014 Common - Uncharacterized protein, YPUA B.subtilis ortholog CAC2758 12 COG4086 COG4086, Predicted secreted protein Function unknown 15895367 Nonpathogen - hypothetical protein CAC2097 1 None None None 15895158 Common - Uncharacterized phage related protein CAC1883 76 COG5283 COG5283, Phage-related tail protein Function unknown 15896419 Common leuB Isopropylmalate dehydrogenase CAC3171 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 15895847 Nonpathogen - GGDEF domain containing protein CAC2587 3 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15896161 Common - Spore coat protein cotS related CAC2908 7 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 15894338 Common - Uncharacterized conserved protein (possible membrane) CAC1051 7 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15893864 Common - Pectate lyase H (FS) CAC0574 9 None None None 15894335 Common - Carbonic anhydrase/acetyltransferase, isoleucine patch superfamily CAC1048 211 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 15894126 Common potB ABC-type spermidine/putrescine transport system, permease component I CAC0839 208 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 15894920 Common - Hypothetical protein, CF-38 family CAC1643 9 COG5620 COG5620, Uncharacterized conserved protein Function unknown 15894869 Common - Uncharacterized membrane protein, YCGQ B. subtilis homolog CAC1591 21 COG3689 COG3689, Predicted membrane protein Function unknown 15894944 Common - HD family hydrolase, diverged CAC1667 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 15896601 Common - Site-specific DNA methylase dam CAC3358 97 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 15893480 Common nagB glucosamine-6-phosphate deaminase CAC0187 81 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 15894531 Common minC septum formation inhibitor CAC1248 96 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 15894905 Common gyrB DNA topoisomerase IV subunit B CAC1627 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15895657 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein CAC2391 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 15896193 Common - Membrane-associated sensory histidine kinase-like ATPase CAC2940 154 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 15895626 Common rplT 50S ribosomal protein L20 CAC2359 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 15896716 Nonpathogen - hypothetical protein CAC3479 1 None None None 15895650 Nonpathogen - hypothetical protein CAC2384 1 None None None 15894210 Nonpathogen - Predicted membrane protein; CF_1 family CAC0923 1 None None None 15894166 Common - ABC-type polar amino acid transport system, ATPase component CAC0879 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15896561 Common - hypothetical protein CAC3318 2 None None None 15895449 Common - GDP-D-mannose dehydratase CAC2180 228 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 15893602 Common abrB Regulators of stationary/sporulation gene expression, abrB B.subtilis ortholog CAC0310 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 15895772 Nonpathogen - Predicted membrane protein CAC2507 1 None None None 15895605 Common - Lysine decarboxylase CAC2338 98 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 15895421 Common fliL Flagellar protein FliL CAC2152 9 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 15896410 Common pabA Para-aminobenzoate synthase component II CAC3162 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 15893388 Common - Uncharacterized predicted membrane protein, YTWI B.subtilis ortholog CAC0092 28 COG2707 COG2707, Predicted membrane protein Function unknown 15896406 Common trpB tryptophan synthase subunit beta CAC3158 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 15895265 Nonpathogen - hypothetical protein CAC1995 1 None None None 15894980 Common - Methyl-accepting chemotaxis protein (fragment) CAC1703 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893685 Common kdgA Deoxyphosphogluconate aldolase (gene kdgA) CAC0394 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 15894790 Common nirC Formate/nitrite family of transporter CAC1512 102 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 15893733 Common - Permease, putative chloride channel CAC0442 148 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 15894299 Common - Uncharacterized membrane protein, homolog of YNGA/YWCD B.suntilis CAC1012 10 COG2246 COG2246, Predicted membrane protein Function unknown 15894025 Common - DNA polymerase III subunit epsilon CAC0738 126 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15894700 Common - Pyruvate-formate lyase-activating enzyme CAC1421 88 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15894780 Common - DNA-methyltransferase (cytosine-specific), ortholog of BSP6I Bsubtilis CAC1501 106 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15893567 Common - hypothetical protein CAC0275 2 None None None 15895645 Common dapB dihydrodipicolinate reductase CAC2379 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 15894998 Common rpiA primosome assembly protein PriA CAC1721 214 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 15894830 Common - Response regulator (CheY-like receiver domain and HTH DNA-binding domain) CAC1552 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895986 Common - Secreted protein containing SH3 domain homolog CAC2729 6 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 15896173 Common tenI Thiamine monophosphate synthase CAC2920 160 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 15893474 Common - Similar to beta-lactamase CAC0181 122 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 15895839 Nonpathogen - hypothetical protein CAC2579 4 None None None 15895928 Common - Glu-tRNAGln amidotransferase subunit A CAC2670 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 15895042 Common - ATPase, possible competence protein ComM CAC1765 193 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 15893468 Common murQ N-acetylmuramic acid-6-phosphate etherase CAC0175 84 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 15894415 Nonpathogen - hypothetical protein CAC1131 1 None None None 15894061 Common - hypothetical protein CAC0774 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 15894230 Common hisE phosphoribosyl-ATP pyrophosphatase CAC0943 180 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 15896318 Nonpathogen - Predicted membrane protein CAC3067 2 None None None 15895723 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta CAC2458 116 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 15893499 Common - hypothetical protein CAC0206 32 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 15894477 Nonpathogen - hypothetical protein CAC1194 1 None None None 15896006 Common - phosphodiesterase CAC2749 46 COG0622 COG0622, Predicted phosphoesterase General function prediction only 15895056 Common - nicotinate phosphoribosyltransferase CAC1780 117 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 15895407 Common - putative manganese-dependent inorganic pyrophosphatase CAC2138 55 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 15895537 Common aspS aspartyl-tRNA synthetase CAC2269 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15896612 Common - Predicted transcriptional regulator CAC3370 45 COG1695 COG1695, Predicted transcriptional regulators Transcription 15893313 Common serA D-3-phosphoglycerate dehydrogenase CAC0015 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15896137 Common - Predicted membrane protein CAC2883 1 None None None 15894839 Common - Glycosyltransferase, involved in cell wall biogenesis CAC1561 129 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15896630 Common - Possible S-layer protein CAC3389 52 None None None 15895070 Common - Predicted permease CAC1794 176 COG0628 PerM, Predicted permease General function prediction only 15894472 Nonpathogen - hypothetical protein CAC1189 1 None None None 15895882 Common dapF diaminopimelate epimerase CAC2624 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 15896033 Common - Rubredoxin CAC2778 124 COG1773 COG1773, Rubredoxin Energy production and conversion 15896753 Common - Membrane-associated histidine kinase with HAMP domain CAC3516 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893348 Nonpathogen - Hypothetical protein, CF-3 family K28 CAC0050 1 None None None 15894048 Nonpathogen - Predicted membrane protein CAC0761 1 None None None 15894362 Common - Putative translation initiation inhibitor CAC1077 5 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15895328 Nonpathogen - Predicted membrane protein CAC2058 1 None None None 15894327 Common - Predicted amidohydrolase CAC1040 48 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 15893799 Common uvrC excinuclease ABC subunit C CAC0508 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15894579 Common - N-terminal fragment of elongation factor Ts CAC1297 6 None None None 15894737 Common - PTS system, fructose(mannose)-specific IIB CAC1458 29 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 15894032 Common - Transcriptional regulator, LysR family CAC0745 192 COG0583 LysR, Transcriptional regulator Transcription 15894693 Common - TerE family protein, ortholog of stress responce protein SCP2 (YCEC) B.subtilis CAC1414 29 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 15893988 Common cspR Predicted tRNA-methylase (SpoU class) CAC0700 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 15893440 Common - N-terminal Zn-ribbon domain and C-terminal MutT domain, YJAD ortholog CAC0145 3 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 15893894 Common - Predicted phosphatase CAC0605 78 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15895014 Common - N6-adenine-specific methylase CAC1737 214 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 15896643 Common - Dipeptidyl aminopeptidase/acylaminoacyl-peptidase related protein CAC3402 37 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 15894234 Common - Predicted membrane protein, hemolysin III homolog CAC0947 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 15893302 Common recF recombination protein F CAC0004 155 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 15895105 Common - Predicted inactivated Zn-dependent peptidase, PMBA ortholog CAC1829 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15894306 Common - Phospholipase C related protein CAC1019 6 None None None 15895662 Common - Predicted xylanase/chitin deacetylase CAC2396 101 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15895955 Common - hypothetical protein CAC2697 2 None None None 15894099 Common - Pectate lyase related protein, secreted CAC0812 13 None None None 15894181 Common aroB 3-dehydroquinate synthetase CAC0894 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 15895077 Common - hypothetical protein CAC1801 19 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 15896671 Common - Membrane associated, signal transduction histidine kinase-like ATPase CAC3430 112 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 15896619 Common - Xylanase/chitin deacetylase family enzyme CAC3377 102 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15893765 Nonpathogen - ACT domain containing transcriptional regulators, related to gcvR of E.coli CAC0474 4 None None None 15893490 Common - Transcriptional regulator, MarR/EmrR family CAC0197 85 COG1846 MarR, Transcriptional regulators Transcription 15894086 Common psd Phosphatidylserine decarboxylase CAC0799 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 15895490 Common cheB Chemotaxis protein CheB, (CheY-like receiver domain and methylesterase domain) CAC2222 220 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 15896593 Common - Putative intracellular protease/amidase (ThiJ family) CAC3350 102 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15894354 Nonpathogen - Hypothetical protein, CF-25 family CAC1068 1 None None None 15895211 Nonpathogen - Predicted HD superfamily hydrolase CAC1938 2 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 15895451 Nonpathogen - hypothetical protein CAC2182 1 None None None 15894465 Nonpathogen - Phage related protein, YorG B.subtilis homolog CAC1182 4 None None None 15893461 Common - Possible sigma factor, diverged member of sigF/sigE/sigG family CAC0167 76 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 15894057 Common - Glycerol uptake facilitator protein, permease CAC0770 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 15894041 Common - hypothetical protein CAC0754 3 None None None 15894292 Nonpathogen - Uncharacterized protein similar to Cylindrotheca fusiformis plasmid hypothetical protein (GI:99319) CAC1005 1 None None None 15894491 Common - hypothetical protein CAC1208 27 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 15895797 Common - HD_GYP hydrolase domain fused to HD hydrolase domain CAC2534 119 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15896457 Common - Predicted RNA-binding protein, YABO B.subtilis ortholog CAC3210 43 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 15895108 Common - Cystathionine beta-lyase family protein, YNBB B.subtilis ortholog CAC1833 29 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 15896425 Common cysS cysteinyl-tRNA synthetase CAC3177 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15895802 Common - Co/Zn/Cd efflux system component CAC2540 196 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 15895205 Nonpathogen - hypothetical protein CAC1932 1 None None None 15896837 Common - Transcriptional regulator, FadR family CAC3603 141 COG2186 FadR, Transcriptional regulators Transcription 15894201 Nonpathogen - Cellulosome integrating cohesin-containing protein, secreted CAC0914 1 None None None 15893521 Common - Predicted Zn-dependent protease, TLDD ortholog CAC0229 166 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15895396 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase CAC2127 206 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15895514 Common - Lysophospholipase L2 PLDB, hydrolase of alpha/beta superfamily CAC2246 64 COG2267 PldB, Lysophospholipase Lipid metabolism 15896126 Nonpathogen - Predicted membrane protein in FoF1-type ATP synthase operon CAC2872 1 None None None 15893514 Common exoA Exodeoxyribonuclease (exoA) CAC0222 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15893528 Common - ABC-type multidrug transport system, ATP-ase component CAC0236 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15893646 Common - Putative polygalacturonase (pectinase) CAC0355 28 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 15895282 Common fadB Enoyl-CoA hydratase CAC2012 153 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 15894376 Common - putative aminopeptidase 1 CAC1091 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 15894437 Nonpathogen - hypothetical protein CAC1154 1 None None None 15893986 Common - Predicted hydrolase of the HAD superfamily CAC0698 157 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15894754 Common - Proline/glycine betaine ABC transport system, ATPase component CAC1475 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 15894837 Common - Predicted transcriptional regulator CAC1559 18 COG1396 HipB, Predicted transcriptional regulators Transcription 15895295 Nonpathogen - hypothetical protein CAC2025 3 None None None 15894442 Nonpathogen - hypothetical protein CAC1159 1 None None None 15893639 Common - Hypothetical protein, CF-21 family CAC0348 3 None None None 15896210 Common - PTS system IIB component (galactitol/fructose specific) CAC2957 4 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 15894157 Nonpathogen - hypothetical protein CAC0870 1 None None None 15893557 Common - Transcriptional regulator, GntR family CAC0265 52 COG1725 COG1725, Predicted transcriptional regulators Transcription 15895678 Common - hypothetical protein CAC2412 8 COG4127 COG4127, Uncharacterized conserved protein Function unknown 15895972 Nonpathogen - hypothetical protein CAC2715 1 None None None 15896488 Common - Membrane associated methyl-accepting chemotaxis protein CAC3243 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894555 Common holA DNA polymerase III subunit delta CAC1273 51 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 15895049 Common sacC Levanase CAC1773 52 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 15894312 Common nadA quinolinate synthetase CAC1025 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 15895859 Nonpathogen - Predicted membrane protein CAC2600 5 None None None 15896206 Common lacB galactose-6-phosphate isomerase subunit LacB CAC2953 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 15895852 Nonpathogen - 6-pyruvoyl-tetrahydropterin synthase related domain; conserved membrane protein CAC2592 6 COG5617 COG5617, Predicted integral membrane protein Function unknown 15893802 Common - hypothetical protein CAC0511 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 15896027 Common - Permease CAC2772 134 COG2252 COG2252, Permeases General function prediction only 15896526 Common - ABC-type multidrug/protein/lipid transport system, ATPase component CAC3281 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15896700 Common - Hypothetical protein, CF-28 family CAC3460 1 None None None 15893996 Common - Putative transcriptional regulator CAC0708 62 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 15896530 Common - Predicted amino acid transporter CAC3285 169 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15896188 Common - Predicted acetyltransferase CAC2935 39 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 15895122 Common lytB 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein CAC1847 232 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 15894860 Common - Membrane associated histidine kinase-like ATPase CAC1582 13 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 15896284 Common - Uncharacterized protein containing conserved domain, related to YABE B.subtilis C-terminal domain CAC3033 21 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 15896350 Common truA tRNA pseudouridine synthase A CAC3099 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 15895126 Common - Predicted pseudouridylate synthase CAC1851 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15896356 Common rpsD 30S ribosomal protein S4 CAC3105 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15895670 Common - Glycosyltransferase CAC2404 92 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15893842 Common - Protein containing cell-adhesion domain CAC0552 15 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15895252 Common - hypothetical protein CAC1981 5 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15895378 Common - Acetyltransferase CAC2109 186 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15896940 Common - DNA segregation ATPase, FtsK/SpoIIIE family, YUKA B.subtilis ortholog CAC3709 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15895031 Common ffh Signal recognition particle GTPase Ffh CAC1754 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 15893454 Common - hypothetical protein CAC0159 1 None None None 15894258 Common citB aconitate hydratase CAC0971 223 COG1048 AcnA, Aconitase A Energy production and conversion 15894591 Common - Integrase XerD family protein (similarity only with C-term. part CAC1310 164 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15894075 Common - Ferrichrome transport permease CAC0788 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15893485 Common - Similar to chloromuconate cycloisomerase CAC0192 147 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 15895702 Common - hypothetical protein CAC2437 66 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 15894557 Common - germination protease CAC1275 15 None None None 15895827 Common - Superoxide dismutase (Fe/Mn family) CAC2567 144 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 15896966 Common jag Predicted RNA-binding protein Jag, SpoIIIJ-associated CAC3735 71 COG1847 Jag, Predicted RNA-binding protein General function prediction only 15894006 Common - Ortholog ycnD B.subtilis, nitroreductase CAC0718 107 COG0778 NfnB, Nitroreductase Energy production and conversion 15894549 Common dacB D-alanyl-D-alanine carboxypeptidase CAC1267 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15894155 Common - Predicted membrane protein CAC0868 2 COG1511 COG1511, Predicted membrane protein Function unknown 15896779 Nonpathogen - Predicted membrane protein CAC3543 1 None None None 15896070 Nonpathogen - hypothetical protein CAC2815 1 None None None 15894251 Nonpathogen - hypothetical protein CAC0964 1 None None None 15896300 Common - Glycosyltransferase CAC3049 210 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15893423 Common recR recombination protein RecR CAC0127 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15894384 Common coaE dephospho-CoA kinase CAC1099 174 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 15895038 Common rbgA ribosomal biogenesis GTPase CAC1761 110 COG1161 COG1161, Predicted GTPases General function prediction only 15895601 Common - UDP-glucose 4-epimerase CAC2334 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15894187 Common - Possible Zn-finger containing protein CAC0900 2 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 15894733 Common - Membrane associated histidine kinase-like ATPase CAC1454 145 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 15894745 Common - hypothetical protein CAC1466 6 COG2128 COG2128, Uncharacterized conserved protein Function unknown 15895888 Common - Uncharaterized conserved protein, YOME B.subtilis ortholog CAC2630 23 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 15895786 Common - Glycosyltransferase CAC2522 178 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15893359 Common - hypothetical protein CAC0062 9 COG4722 COG4722, Phage-related protein Function unknown 15895638 Common - S-adenosylmethionine-dependent methyltransferase CAC2371 63 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 15893713 Common licT Transcriptional antiterminator licT CAC0422 29 COG3711 BglG, Transcriptional antiterminator Transcription 15894897 Common - hypothetical protein CAC1619 1 None None None 15894101 Common - 3-oxoacyl-[acyl-carrier-protein] synthase III CAC0814 195 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 15896315 Common - UDP-N-acetylglucosamine 2-epimerase CAC3064 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 15896913 Common kdpB/atkB potassium-transporting ATPase subunit B CAC3681 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 15895434 Common flgB flagellar basal body rod protein FlgB CAC2165 65 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 15896114 Common - hypothetical protein CAC2860 5 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 15896529 Common - Uncharacterized conserved protein, DegV family CAC3284 49 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 15894774 Common - Enzyme of dihydrofolate reductase family, ortholog YWFD B.subtilis CAC1495 75 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 15894634 Common - Transcriptional antiterminator (BglG family) CAC1355 29 COG3711 BglG, Transcriptional antiterminator Transcription 15895592 Common - Possible cell wall hydrolase containing N-acetylglucosaminidase domain and ChW-repeats CAC2325 12 COG4193 LytD, Beta- N-acetylglucosaminidase Carbohydrate transport and metabolism 15894867 Common malS Malic enzyme CAC1589 199 COG0281 SfcA, Malic enzyme Energy production and conversion 15896824 Common - Predicted flavoprotein, YhiN family CAC3590 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 15896702 Common fabG 3-oxoacyl-acyl carrier protein reductase CAC3462 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15894624 Common xylT D-xylose-proton symporter CAC1345 176 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896309 Common - Mannose-1-phosphate guanylyltransferase CAC3058 162 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 15893726 Nonpathogen - hypothetical protein CAC0435 1 None None None 15894305 Common - Predicted membrane protein CAC1018 1 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 15895209 Common - hypothetical protein CAC1936 7 COG4712 COG4712, Uncharacterized protein conserved in bacteria Function unknown 15895996 Common - Predicted acetyltransferase CAC2739 30 COG3981 COG3981, Predicted acetyltransferase General function prediction only 15893447 Common - Ribosomal-protein-alanine acetyltransferase (acetylating enzyme for N-terminal of ribosomal protein S5) CAC0152 111 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15893708 Common - Similar to arsenate reductase CAC0417 9 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 15896784 Nonpathogen - Uncharacterized conserved Zn-finger containing protein CAC3548 3 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 15893844 Common lyc Autolytic lysozime (1,4-beta-N-acetylmuramidase), family 25 of glycosyl hydrolase ; peptodoglycan-binding domain CAC0554 51 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 15895486 Common cheY Chemotaxis signal receiving protein CheY CAC2218 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 15894337 Common nadE NAD synthetase CAC1050 187 COG0171 NadE, NAD synthase Coenzyme metabolism 15895745 Common - Predicted acetyltransferase CAC2480 61 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15896668 Common - PTS system, (possibly glucose-specific) IIA component CAC3427 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 15893731 Nonpathogen - Homolog of osmotically induced OSMY protein of E.coli CAC0440 6 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 15893366 Common - Predicted iron-binding protein, hemerythrin CAC0069 48 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 15893503 Common bioB Biotine synthase (gene bioB) CAC0210 191 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15896893 Nonpathogen - Uncharacterized protein, homolog of Desulfovibrio gigas (gi:6978031) CAC3660 5 None None None 15894297 Common - Predicted phosphohydrolase, Icc family CAC1010 2 None None None 15895299 Nonpathogen - hypothetical protein CAC2029 1 None None None 15894801 Common - Fructokinase CAC1523 27 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15893973 Common - Putative Mn transporter, NRAMP family CAC0685 103 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 15896843 Common - ABC-type MDR transport system, permease component CAC3609 20 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15895501 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CAC2233 217 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 15894374 Common - HPr kinase/phosphorylase CAC1089 82 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 15894146 Common - putative anti-SigV factor CAC0859 6 None None None 15896153 Common splB Spore photoproduct lyase, SPL related protein CAC2900 20 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 15895385 Common - General stress protein, DnaK suppressor DskA, YTEA B.subtilis ortholog CAC2116 135 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15896737 Common - anaerobic C4-dicarboxylate transporter CAC3500 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 15896365 Common rpmD 50S ribosomal protein L30 CAC3115 124 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 15895907 Common - hypothetical protein CAC2649 7 COG5523 COG5523, Predicted integral membrane protein Function unknown 15896094 Common - Inactive homolog of metal-dependent protease. YDIC B.subtilis ortholog CAC2839 184 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 15895977 Common - Sensory protein containing histidine kinase, PAS anf GAF domains CAC2720 89 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15895816 Nonpathogen - hypothetical protein CAC2554 1 None None None 15894381 Common - Uncharacterized protein, YjiN homolog CAC1096 48 COG2733 COG2733, Predicted membrane protein Function unknown 15896040 Nonpathogen - hypothetical protein CAC2785 1 None None None 15894637 Nonpathogen - hypothetical protein CAC1358 1 None None None 15896725 Common - Predicted transcriptional regulator CAC3488 115 COG1733 COG1733, Predicted transcriptional regulators Transcription 15896292 Common - O-actetyl transferase related protein CAC3041 16 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 15894739 Common - PTS system, fructose(mannose)-specific IID CAC1460 37 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 15893893 Common - Acyl carrier protein phosphodiesterase CAC0604 72 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 15895275 Common - Siderophore/Surfactin synthetase related protein CAC2005 2 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 15894046 Common - hypothetical protein CAC0759 2 None None None 15895612 Common - Glycosyltransferase CAC2345 165 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894266 Common - Uncharacterized protein containing two CBS domains CAC0979 165 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 15893350 Nonpathogen - Hypothetical protein, CF-18 family CAC0052 1 None None None 15894873 Common - Integrase/recombinase, XerC/XerD family CAC1595 21 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15894804 Common - Amidase, related to GSP of E.coli CAC1526 3 None None None 15894485 Nonpathogen - hypothetical protein CAC1202 2 None None None 15894551 Common - Cation transport ATPase CAC1269 170 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 15895098 Common - Fusion of predicted Zn-dependent amidase/peptidase (cell wall hydrolase/DD-carboxypeptidase family) and uncharacterized domain of ErfK family; peptodoglycan-binding domain CAC1822 18 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15895081 Common truB tRNA pseudouridine synthase B CAC1805 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 15894263 Common - Uncharacterized conserved protein, ortholog yuzA B.subtilis CAC0976 25 COG2155 COG2155, Uncharacterized conserved protein Function unknown 15896936 Nonpathogen - Hypothetical protein, CF-37 family(almost identical) CAC3705 1 None None None 15896745 Common - Predicted aminopeptidase CAC3508 6 COG2234 Iap, Predicted aminopeptidases General function prediction only 15895823 Common - Predicted acetyltransferase CAC2561 33 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15894720 Nonpathogen - hypothetical protein CAC1441 1 None None None 15895571 Common SpoVAD stage V sporulation protein AD CAC2304 15 None None None 15894274 Common - hypothetical protein CAC0987 1 None None None 15893560 Common - ABC transporter ATP-binding protein CAC0268 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15895757 Nonpathogen - Predicted membrane, YNAG B.subtilis ortholog CAC2492 1 None None None 15895754 Nonpathogen - Predicted membrane protein CAC2489 1 None None None 15894482 Nonpathogen - hypothetical protein CAC1199 1 None None None 15894570 Common rpsU 30S ribosomal protein S21 CAC1288 112 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 15895190 Nonpathogen - hypothetical protein CAC1916 1 None None None 15896017 Common - Thiamine biosynthesis lipoprotein ApbE CAC2761 134 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 15896851 Common - Uncharacterized membrane protein, YHAG B.subtilis homolog CAC3617 5 None None None 15896552 Common - Predicted membrane protein CAC3309 31 None None None 15896927 Common - Possible transcriptional regulator, containing DNA-binding domain of xre family CAC3695 3 None None None 15896949 Common - Exopolyphosphatase-like domain and PAS domain containing protein, YYBT B.subtilis ortholog CAC3718 93 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 15895698 Common - HtrA-like serine protease (with PDZ domain) CAC2433 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15894515 Common - Predicted lytic murein transglycosylase (N-term. LysM motif repeat domain) CAC1232 90 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 15894594 Nonpathogen - hypothetical protein CAC1314 1 None None None 15894140 Common - HD superfamily hydrolase (HD-GYP domain) CAC0853 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15896683 Common polC DNA polymerase III (alpha subunit) CAC3442 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 15896871 Common - Oligopeptide ABC transporter, permease component CAC3637 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15894128 Common - Predicted transcriptional regulator CAC0841 114 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 15893655 Common - Metal-dependent hydrolase of the metallobeta-lactamase superfamily CAC0364 11 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 15894972 Common sigE sporulation sigma factor SigE CAC1695 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15893836 Nonpathogen - Uncharacterized membrane protein, homolog of Methanobacterium (2621593) CAC0546 1 None None None 15896386 Common tuf elongation factor Tu CAC3136 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15896789 Common - Transcriptional regulator (LacI family) CAC3553 126 COG1609 PurR, Transcriptional regulators Transcription 15896219 Common lacR Lactose phosphotransferase system repressor lacR CAC2966 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15894390 Nonpathogen - hypothetical protein CAC1105 1 None None None 15895582 Common - DTDP-4-dehydrorhamnose reductase, rfbD ortholog CAC2315 184 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 15893310 Common - Predicted dehydrogenase with iron-sulfur domain CAC0012 22 COG0579 COG0579, Predicted dehydrogenase General function prediction only 15895937 Common - Pullulanase CAC2679 151 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 15895429 Common fliH Flagellar assembly protein FliH CAC2160 12 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15896065 Nonpathogen - Possible glucoamylase (diverged), 15 family CAC2810 15 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 15895781 Nonpathogen - hypothetical protein CAC2516 1 None None None 15896221 Common - Mannose-1-phosphate guanylyltransferase CAC2968 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 15895559 Nonpathogen - hypothetical protein CAC2291 1 None None None 15893811 Common - hypothetical protein CAC0521 5 None None None 15895369 Nonpathogen - hypothetical protein CAC2099 1 None None None 15896655 Common - ABC-type multidrug/protein/lipid transport system, ATPase component CAC3414 244 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15895742 Nonpathogen - hypothetical protein CAC2477 1 None None None 15894406 Nonpathogen - Predicted membrane protein CAC1121 1 None None None 15894849 Common - Glutathione peroxidase CAC1571 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 15896176 Common - thiamine biosynthesis protein ThiF CAC2923 224 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 15893365 Common - (FS) similar to ABC transporter (permease), YXDM B.subtilis ortholog CAC0068 6 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 15893793 Common uvrB excinuclease ABC subunit B CAC0502 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 15893906 Common - Uncharacterised permease, similar to ABC transporter (permease) CAC0618 168 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 15894521 Common - hypothetical protein CAC1238 1 None None None 15894342 Common - hypothetical protein CAC1055 1 None None None 15894844 Common - Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) CAC1566 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15896793 Nonpathogen - Probable S-layer protein CAC3558 7 None None None 15894059 Nonpathogen - Cobalt permease CAC0772 16 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15896587 Common - Uncharacterized protein, homolog of hypothetical protein (GI:5918205) from Pseudomonas stutzeri CAC3344 22 None None None 15893920 Common - Predicted phosphatase CAC0632 197 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15894136 Common - Predicted transcriptional regulator CAC0849 153 COG1733 COG1733, Predicted transcriptional regulators Transcription 15896563 Common - Predicted secreted protein homolog of yjcM/yhbB B.subtilis CAC3320 14 None None None 15894653 Common cbiP cobyric acid synthase CAC1374 155 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 15893909 Common - Exopolyphosphatase CAC0621 183 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 15894456 Nonpathogen - hypothetical protein CAC1173 1 None None None 15896259 Common - ATPase component of MDR-type ABC transporter, two ATPase domains CAC3007 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15893676 Common - Beta-glucosidase CAC0385 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15894688 Nonpathogen - Predicted membrane protein CAC1409 1 None None None 15894197 Common - Probably cellulosomal scaffolding protein precursor, secreted; cellulose-binding and cohesin domain CAC0910 36 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 15896038 Common cysD O-acetylhomoserine sulfhydrylase CAC2783 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 15894951 Common gltB Small subunit of NADPH-dependent glutamate synthase CAC1674 195 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 15894662 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase CAC1383 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 15896290 Common - Hypothetical secreted protein CAC3039 5 None None None 15894564 Common dnaK molecular chaperone DnaK CAC1282 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15895235 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase related enzyme CAC1963 133 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 15895679 Common - Predicted membrane protein CAC2413 18 COG4708 COG4708, Predicted membrane protein Function unknown 15895576 Common - DNA modification methyltransferase CAC2309 40 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 15893855 Common - Histidine kinase (HAMP, HisKA and HATPase domains) CAC0565 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 15895687 Common - Predicted enzyme with TIM-barrel fold CAC2421 7 None None None 15895523 Common - Predicted permease CAC2255 6 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15896500 Common - hypothetical protein CAC3255 1 None None None 15894880 Common - Predicted diverged CheY-domain CAC1602 4 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 15895185 Common - hypothetical protein CAC1911 2 None None None 15893372 Common - Predicted permease CAC0076 110 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15894852 Common - NAD-dependent 4-hydroxybutyrate dehydrogenase CAC1574 162 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 15895179 Nonpathogen - hypothetical protein CAC1905 1 None None None 15894115 Nonpathogen - hypothetical protein CAC0828 1 None None None 15895195 Nonpathogen - hypothetical protein CAC1921 1 None None None 15895398 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CAC2129 216 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15894604 Common - Uncharacterized predected metal-binding protein CAC1324 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 15895095 Common aspB aspartate aminotransferase CAC1819 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15896588 Common - Transcriptional regulator, AcrR family CAC3345 59 COG1309 AcrR, Transcriptional regulator Transcription 15893941 Common - Response regulator (CheY-like receiver domain and HTH DNA binding domain) CAC0653 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15894934 Common - Uncharacterized conserved protein, yisX B.subtilis ortholog CAC1657 50 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15896088 Common - Uncharacterized conserved protein, YAEG family CAC2833 40 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 15894247 Common - Predicted xylanase related protein CAC0960 36 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15896082 Common - S-adenosylmethionine-dependent methyltransferase CAC2827 72 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15893776 Common - TRNA-processing ribonuclease BN CAC0485 81 COG1295 Rbn, Predicted membrane protein Function unknown 15893607 Common - Predicted acetyltransferase CAC0315 27 COG3981 COG3981, Predicted acetyltransferase General function prediction only 15895411 Common - hypothetical protein CAC2142 1 None None None 15893782 Common - Uncharacterized probably secreted protein, homolog of YDCC B.subtilis CAC0491 4 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 15893777 Nonpathogen - hypothetical protein CAC0486 1 None None None 15894373 Common glpX fructose 1,6-bisphosphatase II CAC1088 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 15893975 Common cysE Serine acetyltransferase CAC0687 217 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 15894052 Common - Fe-S oxidoreductase CAC0765 51 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 15895311 Common - ABC transported MDR-type, permease component CAC2041 6 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15894677 Common - hypothetical protein CAC1398 19 COG0011 COG0011, Uncharacterized conserved protein Function unknown 15895691 Common - hypothetical protein CAC2426 32 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 15893948 Nonpathogen - Hypothetical protein, CF-26 family CAC0660 1 None None None 15895319 Nonpathogen - Predicted membrane protein CAC2049 1 None None None 15896185 Common - ABC-type MDR transporter, ATPase component CAC2932 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15896110 Common metK S-adenosylmethionine synthetase CAC2856 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 15895466 Common acpA Acyl carrier protein CAC2198 6 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15896391 Common rpoC DNA-directed RNA polymerase subunit beta' CAC3142 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15894543 Common - Predicted RNA-binding protein containing KH domain CAC1261 91 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 15893577 Common - DNA-damage repair protein, dinP/uvrX ortholog CAC0285 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 15893742 Common - Sensory transduction histidine kinase (HAMP, HisKA, HATPase domains) CAC0451 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15894965 Common - Penicillin-binding protein CAC1688 184 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15894180 Common - Prephenate dehydrogenase CAC0893 155 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 15896639 Common - Uncharacterized conserved protein, YbhB family CAC3398 64 COG1881 COG1881, Phospholipid-binding protein General function prediction only 15894108 Common - Transcriptional regulator (TetR/AcrR family) CAC0821 55 COG1309 AcrR, Transcriptional regulator Transcription 15893478 Common - Uncharacterized membrane protein, YBBC B.subtilis ortholog CAC0185 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 15896031 Nonpathogen - hypothetical protein CAC2776 3 None None None 15895218 Common - Phage related anti-repressor protein CAC1945 8 COG3561 COG3561, Phage anti-repressor protein Transcription 15896888 Common - Heavy-metal transporting P-type ATPase CAC3655 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15894664 Common cobC Alpha-ribazole-5'-phosphate phosphatase, CobC CAC1385 192 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 15896238 Common ksgA dimethyladenosine transferase CAC2986 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 15893880 Common ribB riboflavin synthase subunit alpha CAC0591 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 15895492 Common cheW Chemotaxis protein CheW CAC2224 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15894699 Common - hypothetical protein CAC1420 57 COG3885 COG3885, Uncharacterized conserved protein Function unknown 15896509 Common - Uncharacterized conserved protein, YTFJ B.subtilis ortholog CAC3264 6 COG3874 COG3874, Uncharacterized conserved protein Function unknown 15895101 Common metB homoserine O-succinyltransferase CAC1825 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 15893349 Nonpathogen - Hypothetical protein, CF-3 family CAC0051 1 None None None 15896595 Common - Membrane associated methyl-accepting chemotaxis protein with HAMP domain CAC3352 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896733 Common - Predicted transcriptional regulator CAC3496 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 15895800 Common - Predicted phosphatase CAC2537 39 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15895672 Common - Predicted permease, possible O-antigen transporter CAC2406 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15896724 Common - Predicted transcriptional regulator CAC3487 69 COG1733 COG1733, Predicted transcriptional regulators Transcription 15896103 Common - Proline/glycine betaine ABC-type transport system, permease component fused to periplasmic component CAC2849 184 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 15895127 Common - Magnesium and cobalt transport protein CAC1852 189 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 15893643 Common - Uncharacterized conserved membrane protein, SANA family CAC0352 63 COG1434 COG1434, Uncharacterized conserved protein Function unknown 15893980 Common uxaC glucuronate isomerase CAC0692 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 15896478 Common - hypothetical protein CAC3232 1 None None None 15896279 Common - Predicted phosphohydrolase CAC3027 88 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 15896032 Common - Glutaredoxin CAC2777 41 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 15895595 Common - Polysaccharide ABC transporter, ATPase component CAC2328 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15895680 Common - Uncharacterized conserved protein, related to alpha-amylase/alpha-mannosidase CAC2414 35 COG1543 COG1543, Uncharacterized conserved protein Function unknown 15894751 Common - Amino acid permease CAC1472 97 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15894418 Common - Phage related protein, YonF B.subtilis homolog CAC1134 4 None None None 15896204 Common lacC Tagatose-6-phosphate kinase CAC2951 125 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 15893332 Common - hypothetical protein CAC0034 1 COG3937 COG3937, Uncharacterized conserved protein Function unknown 15896352 Common - ABC-type transporter, ATPase component (cobalt transporters subfamily) CAC3101 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15894379 Common - Cation efflux system protein CAC1094 197 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 15893342 Nonpathogen - Predicted membrane protein CAC0044 1 None None None 15895375 Common - General secretion pathway protein E, ATPase CAC2105 213 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 15893954 Common - Sugar permease CAC0666 139 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 15895208 Nonpathogen - hypothetical protein CAC1935 1 None None None 15894497 Common - Xre family DNA-binding domain and TPR-repeat containing protein CAC1214 4 None None None 15896049 Common - Transcriptional regulator, Lrp family (possible nitrite reductase regulator NirD) CAC2794 53 COG1522 Lrp, Transcriptional regulators Transcription 15893351 Common - hypothetical protein CAC0053 2 None None None 15894908 Common - Zn-dependent peptidase from MPP family CAC1630 187 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 15896256 Common folA Dihydrofolate reductase CAC3004 147 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 15893784 Common - Uncharcterized small conserved protein, YhhG family CAC0493 12 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 15895258 Common - Ferrichrome-binding periplasmic protein CAC1988 95 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15893438 Common - hypothetical protein CAC0143 1 None None None 15894319 Common - Predicted transcriptional regulator CAC1032 1 COG1522 Lrp, Transcriptional regulators Transcription 15896025 Common - Amino acid transporter CAC2770 70 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15894190 Common - Sensory transduction histidine kinase CAC0903 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893998 Common pgk phosphoglycerate kinase CAC0710 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 15895600 Common spsI DTDP-glucose pyrophosphorylase CAC2333 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15894813 Common - ABC transporter, ATPase component CAC1535 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15894064 Common - Acetyltransferase (the isoleucine patch superfamily) CAC0777 185 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15893815 Common - Sensory transduction histidine kinase (HisKA and HATPase_c domains) CAC0525 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893796 Common - Cell division membrane protein CAC0505 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15896430 Common - Oligopeptide ABC transporter, ATPase component CAC3182 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15896596 Common - hypothetical protein CAC3353 1 None None None 15893665 Common - Similar to ABC transporter (permease) CAC0374 14 None None None 15895623 Common pheT phenylalanyl-tRNA synthetase subunit beta CAC2356 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 15895336 Common - Integrase/recombinase XerD family CAC2066 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15896139 Common - S-adenosylmethionine-dependent methyltransferase, HEMK ortholog CAC2885 233 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15895792 Common - Predicted acetyltransferase CAC2529 7 COG0456 RimI, Acetyltransferases General function prediction only 15894775 Common - Uncharacterized protein, homolog of YCGL B.subtilis CAC1496 8 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 15894958 Common - hypothetical protein CAC1681 17 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 15893299 Common dnaA chromosomal replication initiation protein CAC0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15895725 Nonpathogen - hypothetical protein CAC2460 2 None None None 15896947 Common lonB Lon-like ATP-dependent protease CAC3716 226 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 15893541 Common - Glyoxalase I (glyoxalase family) CAC0249 50 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 15896424 Common ilvN Acetolactate synthase, small subunit CAC3176 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 15895080 Common - Exopolyphosphatase family protein CAC1804 81 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 15893991 Common - Sugar ABC-transporter, ATP-ase component CAC0703 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 15894045 Common - Hypothetical protein, CF-27 family CAC0758 21 None None None 15896076 Common - Methyl-accepting chemotaxis protein CAC2821 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894027 Common - Uncharacterized conserved protein, YlxP family CAC0740 37 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 15895911 Common pyrI aspartate carbamoyltransferase regulatory subunit CAC2653 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 15896131 Common - ABC-type iron (III) transport system, ATPase component CAC2877 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 15895987 Common - Signal transduction histidine kinase CAC2730 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15896347 Common thiK hydroxyethylthiazole kinase CAC3096 78 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 15896063 Common - Beta-lactamase class C domain (PBPX family) containing protein CAC2808 121 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 15893568 Nonpathogen - Uncharacterized possible metal-binding protein CAC0276 1 None None None 15895507 Common glgA Glycogen synthase, glgA CAC2239 131 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 15893496 Common - flavodoxin CAC0203 16 COG0716 FldA, Flavodoxins Energy production and conversion 15893938 Common - Adenilate cyclase, class2 (thermophilic) CAC0650 6 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 15896620 Common - Aldo/keto reductase family enzyme CAC3378 197 COG4989 COG4989, Predicted oxidoreductase General function prediction only 15894692 Common - Similar to C-terminal fragment of toxic anion resistance protein terA CAC1413 19 COG4110 COG4110, Uncharacterized protein involved in stress response General function prediction only 15893390 Common - Ferredoxin-nitrite reductase CAC0094 161 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 15894117 Common - Response regulator CAC0830 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895957 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein CAC2700 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 15893304 Common gyrB DNA gyrase subunit B CAC0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15894184 Common aro Fusion: chorismate mutase and shikimate 5-dehydrogenase CAC0897 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 15893845 Common - Predicted membrane protein CAC0555 13 COG2717 COG2717, Predicted membrane protein Function unknown 15894135 Common - Uncharacterized conserved protein, YitT family CAC0848 57 COG1284 COG1284, Uncharacterized conserved protein Function unknown 15893649 Common - Predicted xylanase/chitin deacetylase CAC0358 39 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15896175 Common thiG thiazole synthase CAC2922 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 15896456 Common - Uncharacterized protein, YABP B.subtilis CAC3209 14 None None None 15895664 Common folC Folylpolyglutamate synthase CAC2398 219 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 15895409 Common flgG flagellar basal body rod protein FlgG CAC2140 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15895456 Common spsE Sialic acid synthase CAC2187 79 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 15894325 Nonpathogen - Predicted metal-binding membrane protein CAC1038 1 COG4640 COG4640, Predicted membrane protein Function unknown 15893952 Common - Sugar-binding periplasmic protein CAC0664 8 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15893404 Common - ABC-type probable sulfate transporter, permease protein CAC0108 191 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 15894252 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase CAC0965 205 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15896003 Common - Membrane associated methyl-accepting chemotaxis protein (with HAMP domain) CAC2746 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896272 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein CAC3020 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 15895564 Common - Transcriptional regulator of MocR family (DNA-binding HTH domain and aminotransferase domain) CAC2297 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 15895417 Common fliR/flhB bifunctional flagellar biosynthesis protein FliR/FlhB CAC2148 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 15894304 Common - SpoVB related membrane protein CAC1017 31 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15893751 Common - CBS-domain containing protein, YHDP B.subtilis ortholog CAC0460 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15894084 Common - Phosphoenolpyruvate synthase CAC0797 147 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15895019 Common eutD phosphotransacetylase CAC1742 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 15895453 Common - hypothetical protein CAC2184 7 COG3955 COG3955, Exopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 15896146 Common - hypothetical protein CAC2893 1 None None None 15893534 Common - Predicted permease CAC0242 11 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15895393 Common - hypothetical protein CAC2124 24 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 15894758 Common ilvE branched-chain amino acid aminotransferase CAC1479 208 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15896523 Common - Uncharacterized protein, containing cell adhesion domain and ChW-repeats CAC3278 22 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15894782 Common - MDR-type permease CAC1504 107 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896152 Nonpathogen - LysM repeats domain containing membrane protein CAC2899 1 None None None 15893484 Common - Transcriptional regulator, RpiR family CAC0191 110 COG1737 RpiR, Transcriptional regulators Transcription 15895034 Common rimM 16S rRNA-processing protein CAC1757 116 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 15896835 Common - Nudix (MutT) family hydrolase CAC3601 74 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15894156 Common - Thioredoxine reductase CAC0869 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15894535 Common - Sporulation protein IVFB related protein, predicted metallopeptidase CAC1253 88 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 15896866 Common oppA Oligopeptide ABC transporter, periplasmic substrate-binding component CAC3632 187 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15895799 Common - Glycosyltransferase CAC2536 205 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15895326 Nonpathogen - hypothetical protein CAC2056 1 None None None 15894741 Common - Levanase/invertase CAC1462 54 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 15895510 Common - Predicted transcriptional regulator, arsE family CAC2242 168 COG0640 ArsR, Predicted transcriptional regulators Transcription 15895264 Common moaB Molybdopterin biosynthesis enzyme, MoaB CAC1994 163 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 15896087 Common - aspartate aminotransferase CAC2832 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15896209 Common - PTS system enzyme IIC component (galactitol/fructose specific) CAC2956 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 15895412 Common sigD Sigma factor of SigD/WhiG family CAC2143 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15896960 Common spoOJ Stage 0 sporulation J, ParB family of DNA-binding proteins CAC3729 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 15894748 Common - Iron-dependent transcription repressor CAC1469 95 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 15896880 Common abrB Transition state regulatory protein AbrB CAC3647 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 15895969 Common crt 3-hydroxybutyryl-CoA dehydratase CAC2712 189 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 15896012 Common - MDR-type ABC transporter (membrane associated ATPase) CAC2756 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15893741 Common - Response regulator (CheY-like and HTH domains) CAC0450 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15896735 Common - Sugar kinase, ribokinase family CAC3498 53 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15894713 Common - Alkaline phosphatase superfamily protein CAC1434 56 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15895517 Common - C-terminal domain of asparagine synthase CAC2249 118 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 15894752 Common - Proline/glycine betaine ABC-type transport system, permease component CAC1473 175 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 15896214 Common galT galactose-1-phosphate uridylyltransferase CAC2961 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 15894413 Nonpathogen - hypothetical protein CAC1129 1 None None None 15894225 Common hisB Imidazoleglycerol-phosphate dehydratase CAC0938 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 15896166 Nonpathogen - hypothetical protein CAC2913 1 None None None 15894481 Common recJ Single-stranded-DNA-specific exonuclease (recJ) CAC1198 159 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15895708 Common - Iron (III) ABC transporter, ATPase component CAC2443 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 15896266 Common thiC thiamine biosynthesis protein ThiC CAC3014 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 15894428 Nonpathogen - hypothetical protein CAC1145 1 None None None 15894805 Common - Spore germination protein GerKB CAC1527 11 None None None 15895383 Common - Predicted pseudouridylate synthase, YLYB B.subtilis ortholog CAC2114 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15894820 Nonpathogen - Predicted membrane protein CAC1542 1 None None None 15894141 Common tet Tetracycline resistance protein tetP, contain GTP-ase domain CAC0854 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15896829 Common - Uncharacterized FAD-dependent dehydrogenase CAC3595 81 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 15896444 Common lysS lysyl-tRNA synthetase CAC3197 247 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15894829 Common - Nitroreductase family protein CAC1551 44 COG0778 NfnB, Nitroreductase Energy production and conversion 15896710 Common - guanosine 5'-monophosphate oxidoreductase CAC3471 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15896143 Common rho transcription termination factor Rho CAC2889 207 COG1158 Rho, Transcription termination factor Transcription 15895547 Common - Heme biosynthesis (nirJ-2) family protein CAC2279 103 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 15896545 Common gerKB Spore germination protein GerKB, membrane protein CAC3301 14 None None None 15896499 Common proA gamma-glutamyl phosphate reductase CAC3254 197 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 15895500 Common recJ SsDNA Exonuclease, RecJ CAC2232 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15896883 Common - HD-GYP domain containing protein CAC3650 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15895524 Common - ABC transporter, ATPase component CAC2256 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15895448 Common - Nucleoside-diphosphate-sugar epimerase CAC2179 224 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15894853 Common - hypothetical protein CAC1575 6 None None None 15895007 Common - ribulose-phosphate 3-epimerase CAC1730 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 161723225 Common - hydroxylamine reductase CAC3428 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 15894107 Common - Conserved protein, ortholog YwqG B.subtilis CAC0820 9 COG3878 COG3878, Uncharacterized protein conserved in bacteria Function unknown 15895231 Common - Uncharacterized protein, YYAC B.subtilis homolog (fragment) CAC1959 10 None None None 15893597 Common motB Chemotaxis motility protein B, gene motB CAC0305 148 COG1360 MotB, Flagellar motor protein Cell motility and secretion 15895428 Common fliL Flagellar-Type ATPase CAC2159 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 15893585 Common - MccF-like protein CAC0293 88 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 15894963 Common - S-adenosylmethionine-dependent methyltransferase CAC1686 121 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 15894996 Common rpoZ DNA-directed RNA polymerase subunit omega CAC1719 8 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 15893804 Common - Uncharacterized conserved protein, similar to B.subtilis yvcL CAC0513 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 15896801 Common topB Topoisomerase B CAC3567 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15894902 Common - Uncharacterized protein from DegV (B.subtilis) family CAC1624 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 15894164 Common cfa Cyclopropane fatty acid synthase CAC0877 141 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 15895144 Common - Predicted transcriptional regulator CAC1869 3 COG1476 COG1476, Predicted transcriptional regulators Transcription 15895659 Common - Uncharacterized ABC transporter, ATPase component CAC2393 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15895853 Common - Uncharacterized conserved membrane protein, YGGA family CAC2593 72 COG1279 COG1279, Lysine efflux permease General function prediction only 15894923 Common - Hypothetical protein, CF-7 family CAC1646 3 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15894792 Common asrB anaerobic sulfite reductase subunit B CAC1514 143 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 15894929 Common aspA aspartate ammonia-lyase CAC1652 212 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 15894232 Common ssb Single-stranded DNA-binding protein CAC0945 204 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15893945 Common - Predicted transposase (5' fragment) CAC0657 33 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 15895063 Common rpsB 30S ribosomal protein S2 CAC1787 248 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 15895774 Common - Predicted acetyltransferase CAC2509 65 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15893479 Common - Xre family DNA-binding domain and TPR-repeat-containing protein CAC0186 20 None None None 15893612 Common - Predicted permease CAC0320 176 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 15895926 Common - hypothetical protein CAC2668 1 None None None 15893826 Common dltE Short-chain dehydrodenase (gene dltE) CAC0536 173 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 15896955 Common rpsF 30S ribosomal protein S6 CAC3724 209 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 15896570 Common - Amino acid ABC-type transporter, ATPase component CAC3327 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15894077 Common fhuD Ferrichrome-binding periplasmic proteinl, fhuD CAC0790 82 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15895048 Common sacB1 Levansucrase CAC1772 16 None None None 15893380 Common - MutT/Nudix family hydrolase CAC0084 16 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15896906 Common - Two CBS domain containing protein CAC3674 5 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 15893435 Common - Predicted permease CAC0140 4 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15896627 Nonpathogen - hypothetical protein CAC3386 2 None None None 15895652 Common - Predicted protein of beta-propeller fold CAC2386 34 COG3391 COG3391, Uncharacterized conserved protein Function unknown 15895962 Common - Uncharacterized membrane protein, homolog of Aquifex (GI:2984271) CAC2705 9 COG4478 COG4478, Predicted membrane protein Function unknown 15895842 Common - Uncharacterized conserved membrane protein, YHGE B.subtilis homolog CAC2582 36 COG1511 COG1511, Predicted membrane protein Function unknown 15896314 Common - Transcriptional regulator, LytR family CAC3063 60 COG1316 LytR, Transcriptional regulator Transcription 15894467 Nonpathogen - hypothetical protein CAC1184 1 None None None 15895435 Common - Nucleoside-diphosphate-sugar epimerase CAC2166 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15894214 Nonpathogen - Hypothetical protein, CF-2 family CAC0927 1 None None None 15896244 Common - Predicted short-chain dehydrogenase CAC2992 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 15896579 Common - Predicted cAMP-binding domain, regulatory protein, diverged CAC3336 33 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15896302 Common - Glycosyltransferase CAC3051 91 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15896766 Nonpathogen - hypothetical protein CAC3529 2 None None None 15894082 Common - Glycosyltransferase involved in cell wall biogenesis CAC0795 178 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15893963 Common - hypothetical protein CAC0675 1 None None None 15893915 Common - Transcriptional regulator, MarR/EmrR family CAC0627 17 COG1846 MarR, Transcriptional regulators Transcription 15894983 Common - Phosphate permease CAC1706 231 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 15895512 Common - HAD superfamily hydrolase, YKRA B.subtilis ortholog CAC2244 73 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15893625 Common - Hypothetical protein, CF-7 family CAC0333 3 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15893738 Common feoA FeoA protein, involved in Fe2+ transport CAC0447 54 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 15894514 Common - Predicted dehydrogenase, YULF B.subtilis ortholog CAC1231 157 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15895979 Common - RCC1 repeats protein (beta propeller fold) CAC2722 35 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 15896603 Common - Transcriptional regulator, LysR family CAC3360 191 COG0583 LysR, Transcriptional regulator Transcription 15894614 Common - Spore coat protein F (COTF) related protein CAC1335 6 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 15896121 Common atpA F0F1 ATP synthase subunit alpha CAC2867 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 15894917 Common - Hypothetical protein, CF-7 family CAC1639 2 None None None 15896481 Common - Uncharacterized conserved protein, YVBJ B.subtilis homolog CAC3235 8 COG4640 COG4640, Predicted membrane protein Function unknown 15893587 Common - Metal-dependent amidohydrolase CAC0295 46 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 15895352 Common xseA exodeoxyribonuclease VII large subunit CAC2082 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 15895532 Common glyA Glycine hydroxymethyltransferase CAC2264 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 15895784 Common - Multimeric flavodoxin (WrbA) domain containing protein CAC2520 53 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15893462 Common - T-RNA-processing ribonuclease BN CAC0168 156 COG1295 Rbn, Predicted membrane protein Function unknown 15894300 Common - FTSA related protein, predicted ATPase of the HSP70 family CAC1013 149 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15896534 Common - Iron-regulated ABC-type transporter membrane component (SufB) CAC3289 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 15896434 Common - hypothetical protein CAC3186 9 None None None 15894636 Common - Uncharacterized predicted metal-binding protein CAC1357 2 None None None 15895519 Common - Uncharacterized conserved membrane protein, affecting LPS biosynthesis CAC2251 20 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 15896558 Common htpG heat shock protein 90 CAC3315 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 15895075 Common nusA transcription elongation factor NusA CAC1799 225 COG0195 NusA, Transcription elongation factor Transcription 15896718 Common - Transcriptional regulator, AcrR family CAC3481 69 COG1309 AcrR, Transcriptional regulator Transcription 15893383 Common - Predicted Co/Zn/Cd cation transporter CAC0087 206 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 15895348 Common - Predicted membrane protein CAC2078 12 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15893683 Nonpathogen - Peptodoglycan-binding domain CAC0392 1 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 15895155 Common - Hypothetical protein, CF-35 family CAC1880 1 None None None 15896822 Common - DNA replication protein DnaC CAC3588 24 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 15894293 Common - MutT-like (Nudix) hydrolase CAC1006 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15894603 Common - NAD(FAD)-dependent dehydrogenase CAC1323 177 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15893694 Common - Secreted protein contains fibronectin type III domains CAC0403 52 None None None 15894173 Nonpathogen - hypothetical protein CAC0886 1 None None None 15896021 Common - Thiamine biosynthesis lipoprotein ApbE CAC2766 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 15894030 Common - 6-phospho-beta-glucosidase CAC0743 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15893631 Common - ADP-ribosylglycohydrolase CAC0339 56 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 15896387 Common fus elongation factor G CAC3138 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15896492 Common - Predicted transcriptional regulator, lacI/xre family CAC3247 3 COG1476 COG1476, Predicted transcriptional regulators Transcription 15893370 Common - Uncharacterized protein, ortholog of YYBG B.subtilis CAC0073 46 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15894941 Common glgP Glycogen phosphorylase CAC1664 139 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 15894488 Nonpathogen - hypothetical protein CAC1205 1 None None None 15895952 Nonpathogen - hypothetical protein CAC2694 1 None None None 15893471 Common appC Oligopeptide transport permease protein CAC0178 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15895944 Common - Possible maltodextrin glucosidase CAC2686 181 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 15894050 Common - Transcriptional regulator, MarR family CAC0763 28 COG1846 MarR, Transcriptional regulators Transcription 15893393 Common hemC porphobilinogen deaminase CAC0097 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 15895242 Nonpathogen - hypothetical protein CAC1971 1 None None None 15894689 Common - Uncharacterized protein with repeats, similar to YCEG B.subtilis CAC1410 4 None None None 15894981 Nonpathogen - hypothetical protein CAC1704 1 None None None 15896358 Common rpsM 30S ribosomal protein S13 CAC3107 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 15896409 Common trpD Anthranilate phosphoribosyltransferase CAC3161 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 15895053 Common - Nudix (MutT-like) hydrolase CAC1777 118 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15895598 Common - DTDP-4-dehydrorhamnose 3,5-epimerase CAC2331 168 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 15895693 Common - Activator of 2-hydroxyglutaryl-CoA dehydratase CAC2428 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 15895233 Common - Predicted phosphohydrolase, Icc family CAC1961 8 COG1409 Icc, Predicted phosphohydrolases General function prediction only 15894121 Common - Predicted integral membrane protein CAC0834 6 None None None 15895302 Common - hypothetical protein CAC2032 2 None None None 15894245 Common - Xre family DNA-binding domain and TPR-repeat-containing protein CAC0958 4 None None None 15893412 Common - Carbone-monoxide dehydrogenase, beta chain CAC0116 28 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 15893335 Common - MinD family ATPase from ParA/SOJ subfamily CAC0037 11 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15895898 Common clpP ATP-dependent Clp protease proteolytic subunit CAC2640 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15895426 Common fliK Flagellar hook-length control protein fliK CAC2157 9 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 15893947 Common - Predicted Zn-dependent peptidase CAC0659 54 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 15896751 Common - Reverse transcriptase/maturase family protein CAC3514 94 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 15896613 Common - 2-enoate reductase (Two distinct NAD(FAD)-dependent dehydrogenase domains) CAC3371 193 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15893562 Nonpathogen - hypothetical protein CAC0270 1 None None None 15895197 Common - hypothetical protein CAC1923 1 None None None 15894969 Common ftsA Cell division protein, ftsA CAC1692 177 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15895992 Common - Response regulator (CheY-like receiver domain and HTH-type DNA-binding) CAC2735 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895373 Nonpathogen - General secretion pathway protein, pilin family CAC2103 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 15896145 Common ctrA CTP synthetase CAC2892 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 15896560 Common - Spore coat protein F (CotF) family protein CAC3317 3 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 15896381 Common rplW 50S ribosomal protein L23 CAC3131 226 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 15895905 Nonpathogen - Diverged arginase family hydrolase CAC2647 3 None None None 15894451 Common - hypothetical protein CAC1168 33 None None None 15895471 Common hag Possible hook-associated protein, flagellin family CAC2203 125 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15894109 Common - ABC transporter, ATP-binding protein CAC0822 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15893833 Common - Methyl-accepting chemotaxis protein CAC0543 156 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894936 Nonpathogen - Predicted membrane protein CAC1659 1 None None None 15894671 Common purF amidophosphoribosyltransferase CAC1392 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 15895452 Nonpathogen - Uncharacterized protein, posible homoloh of YJFB B. subtilis CAC2183 1 None None None 15893419 Common - Cytosine deaminase CAC0123 198 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 15896156 Common - LysM domain containing membrane protein CAC2903 14 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 15895556 Common - Acyl-protein synthetase, luxE CAC2288 14 None None None 15893579 Nonpathogen - Uncharacterized membrane protein CAC0287 1 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 15896929 Nonpathogen - Uncharacterized, Zn-finger domain containing protein, YXKC B.subtilis homolog CAC3697 2 None None None 15894674 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase CAC1395 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 15896580 Common - Predicted amidohodrolase (dihydroorotase family) CAC3337 11 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 15895366 Nonpathogen - hypothetical protein CAC2096 1 None None None 15895192 Nonpathogen - hypothetical protein CAC1918 1 None None None 15894971 Common - Sigma factor E processing enzyme, SpoIIGA CAC1694 14 None None None 15895186 Common - Uncharacterized phage related protein CAC1912 9 None None None 15895647 Common dapD Tetrahydrodipicolinate N-succinyltransferase CAC2381 162 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 15893673 Common levR Possible transcriptional regulator of levanase operon, AAA-ATPase domain (NtrC family), fused to 2 BglG-like domains, ortholog of B.subtilis levR CAC0382 165 COG3933 COG3933, Transcriptional antiterminator Transcription 15895640 Nonpathogen - Predicted membrane protein CAC2373 1 None None None 15893547 Common nifHD Nitrogen regulatory protein PII (nitrogen fixation nifHD) CAC0255 104 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15895287 Nonpathogen - Acyl carrier protein CAC2017 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15894978 Common - Sensory histidine kinase (with HAMP and PAS domains) CAC1701 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 15895178 Common - hypothetical protein CAC1904 1 None None None 15893790 Common - Carboxyl-terminal protease CAC0499 190 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 15894433 Nonpathogen - hypothetical protein CAC1150 1 None None None 15893652 Common kduD 2-deoxy-D-gluconate 3-dehydrogenase CAC0361 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15896493 Common - hypothetical protein CAC3248 3 None None None 15893897 Common lisA Diaminopimelate decarboxilase, lisA CAC0608 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 15896957 Common - hypothetical protein CAC3726 221 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15895118 Common - Predicted transcriptional regulator, YDCN B.subtilis ortholog CAC1843 7 COG1476 COG1476, Predicted transcriptional regulators Transcription 15894743 Common - UVRA-like protein, probably involved in MDR transport CAC1464 248 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 15894904 Common - Glycerol dehydrogenase CAC1626 85 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 15896758 Common - hypothetical protein CAC3521 3 None None None 15895569 Common SpoVAE Stage V sporulation AE, SpoVAE (fragment) CAC2302 7 None None None 15896107 Common - hypothetical protein CAC2853 2 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 15893717 Common - Transcriptional regulator (HTH_ARAC-domain) CAC0426 120 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 15896249 Common - Uracil-DNA glycosylase CAC2997 152 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 15895584 Common tagA Teichoic acid biosynthesis protein, tagA CAC2317 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 15893347 Common - Hypothetical protein, CF-17 family CAC0049 1 None None None 15896464 Common spoVC peptidyl-tRNA hydrolase CAC3217 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 15896506 Common ada Methylated DNA-protein cysteine methyltransferase CAC3261 201 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 15896515 Common - Permease, predicted cation efflux pump CAC3270 95 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15893354 Common - hypothetical protein CAC0057 3 None None None 15895204 Nonpathogen - hypothetical protein CAC1931 1 None None None 15895478 Common - flagellar assembly protein FliW CAC2210 39 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 15894843 Common - Predicted membrane protein CAC1565 2 None None None 15895013 Common recG RecG helicase CAC1736 243 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 15893787 Common - Uncharacterized conserved protein, YitT family CAC0496 66 COG1284 COG1284, Uncharacterized conserved protein Function unknown 15895718 Common - CBS domain containing protein CAC2453 6 None None None 15895825 Common - NifU-related domain containing protein CAC2565 6 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 15896170 Common - acetyl esterase family enzyme CAC2917 59 COG0657 Aes, Esterase/lipase Lipid metabolism 15894015 Common - SAM-dependent methyltransferase CAC0728 40 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15893653 Common - hypothetical protein CAC0362 7 None None None 15895317 Common - Conjugative transfer gene TrsE homolog, ATPase CAC2047 31 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 15894394 Common - Hypothetical protein, CF-8 family CAC1109 2 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 15895734 Common - Lactoylglutathione lyase (fragment) CAC2469 3 None None None 15893715 Common - Fructokinase CAC0424 203 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15896901 Common - Transcriptional regulator, MarR/EmrR family CAC3669 74 COG1846 MarR, Transcriptional regulators Transcription 15895138 Nonpathogen - hypothetical protein CAC1863 1 None None None 15894794 Common - Response regulator (CheY-like receiver domain and HTH DNA-binding domain) CAC1516 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895535 Nonpathogen - hypothetical protein CAC2267 1 None None None 15896460 Common - Possible stage V sporulation protein B, predicted transporter CAC3213 59 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15896689 Common - Probable tesA-like protease CAC3448 113 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 15893679 Nonpathogen - hypothetical protein CAC0388 1 None None None 15894643 Common - Enzyme from phospholipase D family, possible endonuclease nuc CAC1364 58 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15893812 Common - Predicted hydrolase of the HAD superfamily CAC0522 100 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15894021 Common - Glycosyltransferase I (lipopolysaccharide biosynthesis protein-related protein) CAC0734 164 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15895994 Common sbcD DNA repair exonuclease CAC2737 114 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 15896790 Common - Siderophore/Surfactin synthetase related protein CAC3554 7 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 15894710 Common rpiA Ribose 5-phosphate isomerase CAC1431 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 15895560 Nonpathogen - Predicted membrane protein CAC2292 1 None None None 15896699 Nonpathogen - Homolog of cell division GTPase FtsZ, diverged CAC3459 1 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 15896841 Common - Possible ketopantoate reductase PanE/ApbA CAC3607 5 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 15893328 Nonpathogen - hypothetical protein CAC0030 1 None None None 15896782 Common - Highly conserved protein containing a domain related to cellulase catalitic domain and a thioredoxin domain CAC3546 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 15894279 Common - hypothetical protein CAC0992 4 COG5483 COG5483, Uncharacterized conserved protein Function unknown 15893857 Common - Putative methyltransferase CAC0567 170 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15893617 Common - Uncharacterized membrane protein, homolog of YtaF B.subtilis CAC0325 12 COG1971 COG1971, Predicted membrane protein Function unknown 15894460 Nonpathogen - hypothetical protein CAC1177 1 None None None 15896083 Common - Nudix (MutT) family hydrolase/pyrophosphatase CAC2828 168 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15893900 Common - Predicted membrane protein, YohK family CAC0611 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 15896645 Common - Uncharactecterized conserved membrane protein, possible ABC-type MDR permease CAC3404 12 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15896908 Common - hypothetical protein CAC3676 28 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 15894391 Nonpathogen - hypothetical protein CAC1106 1 None None None 15894540 Common - hypothetical protein CAC1258 3 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 15896636 Common - Predicted membrane protein CAC3395 12 None None None 15894365 Common - Uncharacterized protein, probably surface-located CAC1080 13 COG4676 COG4676, Uncharacterized protein conserved in bacteria Function unknown 15894404 Nonpathogen - hypothetical protein CAC1119 1 None None None 15895274 Nonpathogen - Siderophore/Surfactin synthetase related protein CAC2004 1 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 15894409 Nonpathogen - hypothetical protein CAC1125 1 None None None 15894202 Nonpathogen - Endoglucanase A precursor (endo-1,4-beta-glucanase) (cellulase A), secreted; dockerin domain CAC0915 6 None None None 15893993 Common - Sugar ABC transporter, permease protein CAC0705 133 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 15896417 Common ilvB Acetolactate synthase large subunit CAC3169 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15893420 Common - hypothetical protein CAC0124 9 None None None 15894255 Nonpathogen - hypothetical protein CAC0968 1 None None None 15895160 Common - hypothetical protein CAC1885 1 None None None 15894581 Common dnaG DNA primase CAC1299 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15894133 Common - Hypothetical protein, CF-29 family CAC0846 1 None None None 15894573 Common - Uncharacterized protein, YQFD ortholog, related spoIV gene product CAC1291 15 None None None 15893870 Common spoVR Stage V sporulation protein R CAC0581 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 15893727 Common - Predicted xylanase/chitin deacetilase, similar to yxkH B.subtilis CAC0436 116 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15896426 Common proS prolyl-tRNA synthetase CAC3178 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15896931 Nonpathogen - Hypothetical protein, CF-44 family CAC3700 1 None None None 15896666 Common glvC PTS system, (possibly glucose-specific) IIBC component CAC3425 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15893598 Common - SAM-dependent methyltransferase CAC0306 81 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 15894760 Common - Transcriptional regulator, LysR family CAC1481 187 COG0583 LysR, Transcriptional regulator Transcription 15893971 Common - hypothetical protein CAC0683 8 None None None 15894182 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase CAC0895 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 15895749 Common - Predicted membrane, YQJA B.subtilis ortholog CAC2484 10 COG4129 COG4129, Predicted membrane protein Function unknown 15896196 Common - N-terminal domain intergin-like repeats and c-terminal - cell wall-associated hydrolase domain CAC2943 168 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15895091 Common recA recombinase A CAC1815 225 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 15893452 Common MtlD mannitol-1-phosphate 5-dehydrogenase CAC0157 88 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15895627 Common rpmI 50S ribosomal protein L35 CAC2360 18 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 15893316 Common - Putative NADPH-quinone reductase, YabF family CAC0018 90 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15893858 Common asd aspartate-semialdehyde dehydrogenase CAC0568 185 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15894768 Common - Protein of phosphatidic acid phosphatase family, YNBD E.coli ortholog CAC1489 18 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15895164 Common - Uncharacterized phage related protein CAC1889 8 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 15893961 Common - L-serine dehydratase, beta chain CAC0673 61 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 15896747 Common - Membrane associated methyl-accepting chemotaxis protein (with HAMP domain) CAC3510 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894501 Common - Phage related protein, YorS B.subtilis homolog CAC1218 7 COG4502 COG4502, Uncharacterized protein conserved in bacteria Function unknown 15893982 Common - Permease of the Na+: galactoside symporter family CAC0694 80 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15896105 Common - GntR/FadR-family transcriptional regulator fused to conserved membrane protein (YHCF B.subtilis homolog) CAC2851 24 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 15896231 Common gatC Glu-tRNA amidotransferase, subunit C CAC2978 35 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 15894436 Nonpathogen - hypothetical protein CAC1153 1 None None None 15894651 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CAC1372 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 15894547 Common - Translation initiation inhibitor, yabJ B.subtilis ortholog CAC1265 184 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15896654 Common - Transcriptional regulator, MarR/EmrR family CAC3413 44 COG1846 MarR, Transcriptional regulators Transcription 15895401 Common mraW S-adenosyl-methyltransferase MraW CAC2132 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 15895296 Common - Predicted flavodoxin CAC2026 2 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15894062 Common - ATP-utilizing enzyme of the PP-loop superfamily CAC0775 69 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 15896294 Common - CPSC/CAPB subfamily ATPase CAC3043 187 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15894875 Common - Zn-finger DNA-binding domain CAC1597 6 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 15895032 Common rpsP Ribosomal protein S16 CAC1755 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 15895764 Common - Pyruvate ferredoxin oxidoreductase CAC2499 118 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15893748 Common - Transcriptional regulator, AcrR family CAC0457 68 COG1309 AcrR, Transcriptional regulator Transcription 15896093 Common - Predicted nucleotide-binding protein, YjeE family CAC2838 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 15896329 Common - Uncharacterized secreted protein, YBBR Bacillus subtilis homolog CAC3078 24 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 15893556 Common - Predicted membrane protein CAC0264 1 None None None 15896722 Common - Transcriptional regulator, MarR/EmrR family CAC3485 20 COG1846 MarR, Transcriptional regulators Transcription 15895454 Common - hypothetical protein CAC2185 7 COG3955 COG3955, Exopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 15895283 Nonpathogen - hypothetical protein CAC2013 1 None None None 15894355 Common - Transcriptional regulator, AcrR family CAC1070 5 None None None 15893927 Common - Flagellar biosynthesis related protein CAC0639 79 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 15893600 Common - Cell wall-associated hydrolase CAC0308 126 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 15894104 Nonpathogen - hypothetical protein CAC0817 1 None None None 15896899 Common - Membrane transporters of cations and cationic drugs CAC3666 119 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 15894360 Common - Beta-glucosidase family protein CAC1075 125 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 15894448 Nonpathogen - hypothetical protein CAC1165 1 None None None 15895610 Common - LPS biosynthesis O-acetyl transferase CAC2343 64 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 15896813 Common - Transcriptional regulator, MarR/EmrR family CAC3579 75 COG1846 MarR, Transcriptional regulators Transcription 15893838 Common - Predicted metal-dependent hydrolase CAC0548 7 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 15894441 Nonpathogen - hypothetical protein CAC1158 1 None None None 15894189 Nonpathogen - Predicted membrane protein CAC0902 1 None None None 15894326 Common - Membrane protein, TerC homolog CAC1039 84 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15893627 Common - Hypothetical protein, CF-7 family CAC0335 2 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15895813 Common - RNAse H family protein CAC2551 20 COG3341 COG3341, Predicted double-stranded RNA/RNA-DNA hybrid binding protein General function prediction only 15895157 Common - hypothetical protein CAC1882 1 None None None 15896432 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CAC3184 198 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 15894149 Common - Transmembrane protein CAC0862 4 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 15895023 Common plsX fatty acid/phospholipid synthesis protein CAC1746 178 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 15894302 Common - Pseudouridylate synthase CAC1015 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15894386 Nonpathogen - Hypothetical protein, CF-34 family(identical) CAC1101 1 None None None 15893702 Common - Uncharacterized small conserved protein, homolog of YUKE/YFJA CAC0411 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15896119 Common atpD F0F1 ATP synthase subunit beta CAC2865 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 15894008 Nonpathogen - hypothetical protein CAC0720 1 None None None 15895821 Nonpathogen - hypothetical protein CAC2559 2 None None None 15894730 Common - AraC-type DNA-binding domain-containing protein CAC1451 140 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15895811 Nonpathogen - hypothetical protein CAC2549 13 COG4295 COG4295, Uncharacterized protein conserved in bacteria Function unknown 15896476 Common - Hydrogenase subunit (ferredoxin) CAC3230 32 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 15896915 Common - Penicillin-binding protein 2 (serine-type D-Ala-D-Ala carboxypeptidase) CAC3683 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15896679 Common - Transcriptional regulator, (BlaI/MecI subfamily) CAC3438 27 COG3682 COG3682, Predicted transcriptional regulator Transcription 15895632 Common sspA Small acid-soluble spore protein CAC2365 15 None None None 15895150 Nonpathogen - Hypothetical protein, CF-36 family CAC1875 1 None None None 15894861 Common - Predicted P-loop ATPase CAC1583 12 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 15896360 Common infA Translation initiation factor IF-1 CAC3109 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 15895464 Common - hypothetical protein CAC2196 24 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15893363 Common - ABC transporter, ATP-binding protein CAC0066 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15896320 Common - Predicted glycosyltransferase CAC3069 136 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15896777 Common - 2'-5' RNA ligase family protein, diverged CAC3541 1 None None None 15896254 Common - Uncharacterized consrved protein, YHJR B.subtilis family CAC3002 4 COG1633 COG1633, Uncharacterized conserved protein Function unknown 15895768 Nonpathogen - hypothetical protein CAC2503 1 None None None 15895751 Common - Transcriptional regulator, MarR/EmrR family CAC2486 47 COG1846 MarR, Transcriptional regulators Transcription 15894029 Common - Uncharacterized protein, containing predicted phosphatase domain CAC0742 50 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15894888 Common brnQ Branched-chain amino acid permease CAC1610 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 15894590 Common - Uncharacterized low-complexity protein, related to YISX/YYBG B.subtilis CAC1308 36 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15893734 Common - Methyl-accepting chemotaxis protein CAC0443 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15895889 Common - Uncharacterized protein, ErfK family CAC2631 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15895589 Nonpathogen - hypothetical protein CAC2322 1 None None None 15893875 Common - CheX protein (uncharacterized ORF in chemotaxis operon) CAC0586 18 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 15894582 Common sigA RNA polymerase sigma factor RpoD CAC1300 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15894554 Common - Predicted membrane protein CAC1272 2 None None None 15893851 Common - Cellulase CelE ortholog; dockerin domain CAC0561 20 None None None 15896067 Nonpathogen - hypothetical protein CAC2812 1 None None None 15894626 Common - putative translaldolase CAC1347 179 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15896708 Common - Endoglucanase family 5; S-layer homology, cell-adhesion and dockerin domains CAC3469 12 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 15895489 Common cheR Chemotaxis protein methyltransferase, cheR CAC2221 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 15895442 Common - Glycosyltransferase CAC2173 218 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15895704 Common - Predicted membrane protein CAC2439 5 None None None 15895740 Common - Possible 5-Nitroimidazole antibiotics resistance protein, NimA-family CAC2475 32 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 15895046 Common - putative RNA polymerase sigma factor SigI CAC1770 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15894237 Common - Predicted membrane protein CAC0950 61 COG1971 COG1971, Predicted membrane protein Function unknown 15896566 Nonpathogen - Predicted membrane protein CAC3323 1 None None None 15896288 Common ccpA Catabolite control protein, LacI family transcriptional regulator CAC3037 131 COG1609 PurR, Transcriptional regulators Transcription 15894425 Nonpathogen - hypothetical protein CAC1141 1 None None None 15894506 Common dnaE DNA Polymerase III Alpha chain (dnaE) CAC1223 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 15896133 Common upp uracil phosphoribosyltransferase CAC2879 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 15896622 Common - Metallo-beta-lactamase superfamily hydrolase CAC3380 79 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15896818 Common - Predicted permease CAC3584 200 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15894690 Common - Similar to toxic anion resistance protein terA, ortholog of YCEH B.subtilis CAC1411 46 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 15895794 Common - S-adenosylmethionine-dependent methyltransferase CAC2531 35 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15896422 Common leuA putative alpha-isopropylmalate/homocitrate synthase family transferase CAC3174 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15893923 Common - Zinc finger domain CAC0635 14 None None None 15894524 Common radC DNA repair protein RadC CAC1241 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 15894043 Common - Multimeric flavodoxin WrbA CAC0756 24 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15896312 Common - CPSD/CAPA conserved membrane protein of Rol/Cld family CAC3061 91 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 15893494 Common - Transcriptional regulators, AcrR family CAC0201 22 COG1309 AcrR, Transcriptional regulator Transcription 15896647 Common - Transcriptional regulator, MarR/EmrR family CAC3406 18 COG1846 MarR, Transcriptional regulators Transcription 15894956 Common - hypothetical protein CAC1679 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 15895959 Common - Possible signal transduction protein (containing EAL, CBS and GGDEF domains) CAC2702 170 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15896345 Common - Uncharacterized consrved protein, associated with phosphate permease CAC3094 64 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 15896078 Common - hypothetical protein CAC2823 10 COG4997 COG4997, Uncharacterized conserved protein Function unknown 15894499 Nonpathogen - hypothetical protein CAC1216 1 None None None 15895364 Common efp elongation factor P CAC2094 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15895985 Common - Hypothetical protein, CF-30 family CAC2728 3 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15895505 Common glgC glucose-1-phosphate adenylyltransferase CAC2237 191 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 15896634 Nonpathogen - hypothetical protein CAC3393 1 None None None 15896354 Common rplQ 50S ribosomal protein L17 CAC3103 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 15895855 Common - Rieske FeS-domain containing oxidoreductase CAC2596 84 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15895727 Nonpathogen - Hypothetical protein, CF-13 family CAC2462 1 None None None 15893406 Common cysN GTPase, sulfate adenylate transferase subunit 1 CAC0110 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 15895835 Common rubY Rubrerythrin CAC2575 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 15894756 Nonpathogen - hypothetical protein CAC1477 1 None None None 15895403 Common - translation-associated GTPase CAC2134 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 15894725 Nonpathogen - hypothetical protein CAC1446 1 None None None 15893883 Common - pyridoxine biosynthesis protein CAC0594 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 15894119 Common - Fusion: transcriptional regulator and conserved domain CAC0832 13 COG1695 COG1695, Predicted transcriptional regulators Transcription 15893464 Common - Predicted permease CAC0170 19 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15893536 Common - Integral membrane protein (permease) CAC0244 197 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15893709 Common - Predicted phosphatase, HAD family CAC0418 186 COG0546 Gph, Predicted phosphatases General function prediction only 15896945 Common - Molecular chaperone (small heat shock protein), HSP18 CAC3714 148 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 15896268 Common - hypothetical protein CAC3016 13 COG0392 COG0392, Predicted integral membrane protein Function unknown 15894510 Nonpathogen - hypothetical protein CAC1227 1 None None None 15895771 Common - SpoIID-like domain containing protein; peptidoglycan-binding domain CAC2506 68 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 15896349 Common rplM 50S ribosomal protein L13 CAC3098 216 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 15896001 Nonpathogen - Predicted membrane protein CAC2744 3 None None None 15896878 Common - CRO repressor-like DNA-binding protein CAC3645 3 None None None 15893482 Common - Similar to transcriptional regulator, GntR family CAC0189 126 COG2188 PhnF, Transcriptional regulators Transcription 15895017 Common - Uncharcaterized membrane protein, YLBJ B.subtilis homolog CAC1740 14 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 15893422 Common - hypothetical protein CAC0126 77 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 15893867 Common metH B12-dependent methionine synthase CAC0578 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 15894919 Common - Ankyrin repeats containing protein CAC1641 47 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 15895566 Common hflX Predicted GTPase, HflX CAC2299 210 COG2262 HflX, GTPases General function prediction only 15894250 Common uppP undecaprenyl pyrophosphate phosphatase CAC0963 193 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 15894295 Common - Hypothetical protein, CF-30 family CAC1008 3 None None None 15895838 Common - Glycosyltransferase CAC2578 137 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15895474 Common fliS Flagellar protein FliS CAC2206 72 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15893418 Common cheY Chemotaxis respons regulator (cheY) CAC0122 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15894734 Common - Two-component system regulator (CheY domain and HTH-like DNA-binding domain) CAC1455 225 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15896207 Common lacA galactose-6-phosphate isomerase subunit LacA CAC2954 123 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 15896788 Common - Lactate dehydrogenase CAC3552 160 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 15894819 Nonpathogen - Hypothetical protein, CF-36 family CAC1541 1 None None None 15894098 Common - Hydrogenase expression-formation factor (hypD) CAC0811 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15895216 Common - hypothetical protein CAC1943 6 COG4306 COG4306, Uncharacterized protein conserved in bacteria Function unknown 15894601 Common glpK glycerol kinase CAC1321 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 15896376 Common rplP 50S ribosomal protein L16 CAC3126 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 15896148 Common ddlA D-alanine-D-alanine ligase CAC2895 219 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 15895308 Common - Hypothetical protein, CF-23 family CAC2038 3 None None None 15894323 Common pykA Pyruvate kinase CAC1036 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 15894350 Common - TPR-repeat-containing protein CAC1064 105 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15893931 Common - Putative spore germination protein CAC0643 5 None None None 15893642 Common - hypothetical protein CAC0351 3 COG4304 COG4304, Uncharacterized protein conserved in bacteria Function unknown 15896429 Common - Oligopeptide ABC transporter, permease component CAC3181 217 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15896731 Common - Transcription regulator, YOBV B.subtilis homolog CAC3494 95 COG2378 COG2378, Predicted transcriptional regulator Transcription 15893821 Common - Transcriptional regulator, RpiR family CAC0531 49 COG1737 RpiR, Transcriptional regulators Transcription 15895922 Common - Predicted phosphoesterase, YSNB B.subtilis ortholog CAC2664 66 COG0622 COG0622, Predicted phosphoesterase General function prediction only 15896454 Common - hypothetical protein CAC3207 8 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 15893663 Common - Sensory transduction histidine kinase (HisKA and HATPase damains) CAC0372 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15895087 Common - Periplasmic serine protease, YMFB B.subtilis ortholog CAC1811 23 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15896202 Common - Predicted permease CAC2949 106 COG0679 COG0679, Predicted permeases General function prediction only 15894833 Common - Flagellin CAC1555 119 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15895377 Common - Contains cell adhesion domain CAC2107 34 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15895027 Common - SpoVS-related protein CAC1750 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 15895522 Common - Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) CAC2254 219 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15896113 Common spoIIID Stage III sporulation protein D, SpoIIID CAC2859 15 None None None 15894679 Common - ABC transporter, periplasmic binding component CAC1400 105 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 15893330 Common - Transcriptional regulator TetR/AcrR family CAC0032 152 COG1309 AcrR, Transcriptional regulator Transcription 15896030 Common - Phosphohydrolase from calcineurin family CAC2775 62 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 15896555 Common - hypothetical protein CAC3312 30 COG3882 FkbH, Predicted enzyme involved in methoxymalonyl-ACP biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 15893399 Common cysC Adenylylsulfate kinase CAC0103 145 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 15894359 Common - Predicted permease CAC1074 70 None None None 15895729 Common - Hypothetical protein, CF-40 family CAC2464 2 None None None 15896675 Common - hypothetical protein CAC3434 2 None None None 15896923 Nonpathogen - hypothetical protein CAC3691 1 None None None 15895674 Common - Glycosyltransferase CAC2408 61 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15893467 Common - Response regulator, CheY-like receiver domain and HTH DNA-binding domain CAC0174 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15893950 Common - Sugar ABC transporter, periplasmic sugar-bindind protein CAC0662 17 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15893647 Common - hypothetical protein CAC0356 21 None None None 15896598 Common - Polyketide synthase pksE (short-chain alcohol dehydrogenase,acyl-carrier-protein S-malonyltransferase,3-oxoacyl-(acyl-carrier-protein) synthase I domains) CAC3355 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 15894504 Nonpathogen - hypothetical protein CAC1221 1 None None None 15895342 Common - Stage IV sporulation protein B, SpoIVB CAC2072 16 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15895924 Common - hypothetical protein CAC2666 1 None None None 15894066 Common - Amidase related to nicotinamidase CAC0779 32 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 15893700 Nonpathogen - hypothetical protein CAC0409 1 None None None 15895256 Nonpathogen - hypothetical protein CAC1985 1 None None None 15894961 Common - TYPA/BIPA type GTPase CAC1684 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 15895689 Common - HAD superfamily hydrolase CAC2423 103 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15895929 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C CAC2671 156 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 15894495 Nonpathogen - hypothetical protein CAC1212 1 None None None 15894811 Nonpathogen - hypothetical protein CAC1533 1 None None None 15894682 Common - Zn-dependent hydrolase, glyoxylase II family CAC1403 37 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15896729 Common - hypothetical protein CAC3492 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 15895654 Common argD N-acetylornithine aminotransferase CAC2388 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 15893558 Common - ABC transporter, ATP-binding protein CAC0266 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15895549 Common yajC preprotein translocase subunit YajC CAC2281 33 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 15896074 Common murE UDP-N-acetylmuramyl tripeptide synthase, MURE CAC2819 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15893650 Common - Similar to yteR (Bacilus subtilis) CAC0359 20 COG4225 COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins General function prediction only 15894220 Common xylR Transcriptional regulator of NagC/XylR family (xylose repressor) CAC0933 76 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15893828 Common - Beta-mannanase ManB-like enzyme, contains ChW-repeats CAC0538 8 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 15894616 Common - Spore coat protein COTJB CAC1337 9 None None None 15895334 Common deoD purine nucleoside phosphorylase CAC2064 159 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 15893473 Common appF Oligopeptide ABC transporter, ATP-binding protein CAC0180 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 15894280 Common dacF D-alanyl-D-alanine carboxypeptidase (penicilin binding protein) CAC0993 149 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15895480 Common FlgK Flagellar hook-associated protein FlgK CAC2212 123 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 15895715 Common - Desulfoferrodoxin CAC2450 25 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 15896165 Common araN Sugar-binding periplasmic protein CAC2912 24 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15893807 Common dnaE DNA polymerase III DnaE CAC0516 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 15896342 Common - fumarate hydratase CAC3091 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15896542 Common bdhB NADH-dependent butanol dehydrogenase B (BDH II) CAC3298 169 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 15893918 Common - Peptide chain ralease factor 3 (RF-3) CAC0630 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 15896116 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CAC2862 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 15896372 Common rplX 50S ribosomal protein L24 CAC3122 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 15894988 Common engA GTP-binding protein EngA CAC1711 234 COG1160 COG1160, Predicted GTPases General function prediction only 15894162 Common - Predicted permease CAC0875 79 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15896760 Nonpathogen - Hypothetical protein, CF-7 family CAC3523 1 None None None 15896371 Common rplE 50S ribosomal protein L5 CAC3121 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 15896337 Common - Protein containing cell adhesion domain CAC3086 43 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15895545 Common secF preprotein translocase subunit SecF CAC2277 211 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 15895061 Common topA DNA topoisomerase I CAC1785 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15893688 Common - Predicted sugar phosphate aminotransferase involved in capsule formation CAC0397 78 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 15895808 Common - Transcriptional regulator, FadR family CAC2546 156 COG2186 FadR, Transcriptional regulators Transcription 15893913 Common - Possible periplasmic aspartyl protease CAC0625 27 COG4934 COG4934, Predicted protease Posttranslational modification, protein turnover, chaperones 15894070 Common - Uncharacterized low-complexity protein CAC0783 4 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15896549 Common - Thiol peroxidase, TPX CAC3306 98 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15894170 Common - Probable cation efflux pump (multidrug resistance protein) CAC0883 157 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15895129 Common - Nudix (MutT) family hydrolase CAC1854 73 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15896720 Common - Nitroreductase family protein fused to ferredoxin domain CAC3483 61 COG0778 NfnB, Nitroreductase Energy production and conversion 15896415 Common - hypothetical protein CAC3167 12 COG1433 COG1433, Uncharacterized conserved protein Function unknown 15896296 Common - CPSB/CAPC ortholog, PHP family hydrolase CAC3045 41 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15896483 Common msmX Multiple sugar-binding ABC-transporter, MSMX ATP-binding protein CAC3237 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 15895153 Nonpathogen - hypothetical protein CAC1878 1 None None None 15896768 Common - IS605/IS200-like transposase CAC3531 75 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15895844 Common - Protein containing ChW-repeats CAC2584 7 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15895420 Common fliZ Flagellar biosynthesis protein FliZ CAC2151 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 15893681 Common - Cystathionine gamma-synthase CAC0390 208 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15895866 Common - Trancriptional regulator of AraC family CAC2608 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15894516 Common chev Chemotaxis protein CheV ortholog (CheW-like adaptor domain and CheY-like reciever domain) CAC1233 159 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15894080 Nonpathogen - Uncharacterized conserved protein of probably eukaryotic origin CAC0793 2 None None None 15893385 Common serA D-3 phosphoglycerate dehydrogenase CAC0089 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15893758 Common - Uncharacterized membrane protein, homolog of YDAH B.subtilis CAC0467 10 None None None 15893571 Common - Peptidil-prolyl cis-trans isomerase CAC0279 164 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15896868 Common - Oligopeptide ABC transporter, periplasmic substrate-binding component CAC3634 211 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15896532 Common - Predicted membrane protein CAC3287 7 None None None 15893692 Nonpathogen - Hypothetical protein, CF-24 family CAC0401 1 None None None 15895133 Common - MoxR-like ATPase CAC1858 35 COG0714 COG0714, MoxR-like ATPases General function prediction only 15893324 Common - hypothetical protein CAC0026 3 None None None 15894175 Common - Phosphoglycerol transferase MdoB related protein, alkaline phosphatase superfamily CAC0888 62 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15895341 Common - Spo0A protein, (CheY-like receiver domain and HTH-type DNA binding domain) CAC2071 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15895350 Common - Predicted geranylgeranyl pyrophosphate synthase CAC2080 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15893633 Common - hypothetical protein CAC0342 2 None None None 15893595 Common - Ferredoxin CAC0303 195 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 15894776 Common - Uncharacterized protein, homolog of YCGL B.subtilis CAC1497 22 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 15895358 Common - Stage III sporulation protein AF, SpoIIIAF CAC2088 6 None None None 15896236 Common - hypothetical protein CAC2984 1 None None None 15894143 Common - Transcriptional regulator, LacI family (probably maltose operon transcriptional repressor) CAC0856 129 COG1609 PurR, Transcriptional regulators Transcription 15894091 Common - Pectate lyase related protein, secreted CAC0804 18 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 15896442 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase CAC3194 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15895226 Common - Predicted membrane protein CAC1953 16 COG1950 COG1950, Predicted membrane protein Function unknown 15896935 Common - Hypothetical protein, CF-7 family CAC3704 2 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15894227 Common hisA Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase CAC0940 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 15894645 Nonpathogen - Predicted membrane protein CAC1366 1 None None None 15895609 Nonpathogen - Predicted membrane protein CAC2342 4 None None None 15896556 Nonpathogen - Acyl carrier protein, ACP CAC3313 2 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15895515 Common - Site-specific recombinase, DNA invertase Pin homolog CAC2247 43 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15895446 Common - Ucharacterized protein, CGEB homolog CAC2177 20 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 15895410 Nonpathogen - hypothetical protein CAC2141 1 None None None 15894411 Nonpathogen - hypothetical protein CAC1127 1 None None None 15896010 Common - Possible MDR-type permease, YQJV B.subtilis ortholog CAC2753 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896615 Common - Pectin methylesterase CAC3373 21 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 15895059 Common gltT Proton/sodium-glutamate symport protein CAC1783 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 15896848 Nonpathogen - Uncharacterized conserved membrane protein, possible permease CAC3614 1 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15895562 Common - hypothetical protein CAC2295 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 15895261 Common - Uncharacterized protein, YIIM family CAC1991 27 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 15894822 Common - cytidine deaminase CAC1544 121 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 15895323 Nonpathogen - hypothetical protein CAC2053 2 None None None 15894438 Nonpathogen - hypothetical protein CAC1155 1 None None None 15893527 Common - Chloramphenicol acetyltransferase CAC0235 21 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 15896820 Common cinA competence damage-inducible protein A CAC3586 214 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 15895073 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CAC1797 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 15896881 Common - Acetyltransferase (with duplicated domains), possibly RIMI-like protein CAC3648 40 COG0456 RimI, Acetyltransferases General function prediction only 15895667 Common - Activator of 2-hydroxyglutaryl-CoA dehydratase (duplicated HSP70 class ATPase domain) fused to uncharacterized conserved protein CAC2401 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 15894553 Common - ComC competence related protein CAC1271 32 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 15894808 Common lacY galactoside permease CAC1530 27 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15895005 Common - Serine/threonine protein kinase, Pkn2 family (YLOP B.subtilis ortholog) CAC1728 161 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 15893817 Common - Predicted permease, domain duplication CAC0527 39 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15894287 Common - Uncharacterized protein, homolog of yhfF B.subtilis CAC1000 36 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 15895974 Common - ethanolamine ammonia-lyase small subunit CAC2717 53 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 15894931 Common - Zn-dependent metalloprotease, insulinase family CAC1654 59 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 15896335 Common - TPR-repeat-containing protein CAC3084 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 15895094 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase CAC1818 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15896803 Common accD Acetyl-CoA carboxylase beta subunit CAC3569 221 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 15894900 Common - pyridoxamine kinase CAC1622 107 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 15893379 Common - PemK family of DNA-binding proteins CAC0083 27 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 15894332 Common - Predicted permease CAC1045 109 COG2510 COG2510, Predicted membrane protein Function unknown 15894925 Nonpathogen - Hypothetical protein, CF-7 family CAC1648 1 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15895575 Common spoIIAA Anti-anti-sigma factor (antagonist of SpoIIAB) CAC2308 68 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 15894851 Common - Uncharacterized protein, YJDF B.subtilis ortholog CAC1573 8 None None None 15895553 Common ruvA Holliday junction DNA helicase motor protein CAC2285 212 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 15894087 Common ubiA prenyltransferase CAC0800 12 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15895278 Common pksF 3-oxoacyl-(acyl-carrier-protein) synthase CAC2008 211 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15894574 Common - Membrane protein containing HD superfamily hydrolase domain, YQFF ortholog CAC1292 56 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 15894704 Common - DUTPase, dut CAC1425 179 COG0756 Dut, dUTPase Nucleotide transport and metabolism 15894991 Common ansA L-asparaginase CAC1714 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 15894785 Common phoR Sensory transduction histidine kinase (with HAMP domain) CAC1507 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15895130 Nonpathogen - hypothetical protein CAC1855 1 None None None 15895497 Common - Pyruvate:ferredoxin oxidoreductase CAC2229 122 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15896495 Common - glutamate racemase CAC3250 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 15895457 Common - Protein containing a domain related to multimeric flavodoxin WrbA family CAC2188 4 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15893638 Nonpathogen - hypothetical protein CAC0347 1 None None None 15894560 Common lepA GTP-binding protein LepA CAC1278 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 15896513 Common - Uncharacterized conserved membrane protein, possible MDR-type transporter CAC3268 155 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15894055 Common - Transcriptional regulator, LysR family CAC0768 165 COG0583 LysR, Transcriptional regulator Transcription 15894526 Common mreC Shape-determining protein mreC CAC1243 124 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 15893762 Nonpathogen - GrpE protein HSP-70 cofactor CAC0471 1 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15894402 Nonpathogen - hypothetical protein CAC1117 1 None None None 15896856 Common - Possible subunit of benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase CAC3622 13 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 15895176 Nonpathogen - hypothetical protein CAC1902 1 None None None 15895298 Nonpathogen - Hypothetical protein, CF-4 family CAC2028 1 None None None 15893444 Nonpathogen - hypothetical protein CAC0149 1 None None None 15896959 Common - hypothetical protein CAC3728 12 None None None 15894845 Nonpathogen - hypothetical protein CAC1567 1 None None None 15893623 Common - Uncharacterized membrane protein, homolog of YPAA B.subtilis CAC0331 13 COG4684 COG4684, Predicted membrane protein Function unknown 15896181 Common - Predicted membrane protein CAC2928 13 COG3859 COG3859, Predicted membrane protein Function unknown 15895325 Nonpathogen - Predicted transcriptional regulator CAC2055 1 COG1396 HipB, Predicted transcriptional regulators Transcription 15893658 Common rocB Arginine degradation protein (gene rocB) CAC0367 18 COG4187 RocB, Arginine degradation protein (predicted deacylase) Amino acid transport and metabolism 15894341 Common - Arginase CAC1054 150 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 15894771 Common - Uncharacterized protein, YhhW/pirin family CAC1492 145 COG1741 COG1741, Pirin-related protein General function prediction only 15896756 Common - Predicted membrane protein, possible permease CAC3519 9 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15895052 Common - HAD superfamily hydrolase CAC1776 53 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15893905 Common - Hypothetical protein, CF-25 family CAC0617 3 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15895188 Nonpathogen - hypothetical protein CAC1914 1 None None None 15894680 Common - ABC transporter, ATPase component CAC1401 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 15895665 Common valS valyl-tRNA synthetase CAC2399 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15896697 Common - Predicted membrane protein CAC3457 4 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 15895849 Common - Glycosyltransferase CAC2589 161 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15896462 Common prsA peptidylprolyl isomerase CAC3215 139 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15896551 Common - Glycosyltransferase fused to TPR-repeat domain CAC3308 55 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15894840 Common - Predicted membrane protein CAC1562 1 None None None 15894976 Common - Uncharacterized protein, YfiH family CAC1699 176 COG1496 COG1496, Uncharacterized conserved protein Function unknown 15895736 Common - Transcriptional regulator, TetR/AcrR family CAC2471 112 COG1309 AcrR, Transcriptional regulator Transcription 15894191 Common - ATPase with chaperon activity, two ATP-binding domains, ClpC orthologs CAC0904 219 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15893605 Common - Phage shock protein A CAC0313 104 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 15893564 Common - Amino acid transporter CAC0272 51 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15893326 Common hydA Hydrogene dehydrogenase CAC0028 184 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 15894034 Common - Secreted protein containing uncharacterized conserved protein of ErfK family CAC0747 18 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15894992 Common - PLP-dependent aminotransferase CAC1715 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15895850 Nonpathogen - hypothetical protein CAC2590 4 None None None 15895272 Nonpathogen - Predicted iron-sulfur flavoprotein CAC2002 4 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15893319 Common serS seryl-tRNA synthetase CAC0021 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15893619 Common - Bacterioferritin comigratory protein (AHPC/TSA family) CAC0327 218 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15894407 Nonpathogen - hypothetical protein CAC1123 1 None None None 15893846 Common - Uncharacterised conserved protein CAC0556 23 COG2013 COG2013, Uncharacterized conserved protein Function unknown 15896903 Common amyD ABC-type sugar transport system, permease component CAC3671 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 15893305 Common gyrA DNA gyrase subunit A CAC0007 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15893369 Common - hypothetical protein CAC0072 26 COG4309 COG4309, Uncharacterized conserved protein Function unknown 15893902 Common - Spore coat protein F CAC0613 3 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 15893771 Common nrdD anaerobic ribonucleoside triphosphate reductase CAC0480 103 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 15896772 Common - hypothetical protein CAC3536 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 15896687 Common - hypothetical protein CAC3446 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 15895914 Nonpathogen - Protein containing uncharacterized domain from NimC family CAC2656 4 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 15894089 Common - hypothetical protein CAC0802 13 None None None 15895315 Common - Secreted protein containing domain of murein hydrolase (MLTA homolog) CAC2045 10 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 15896796 Common - ABC-type transporter, permease component CAC3561 58 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15896920 Common - Membrane-associated methyl-accepting chemotaxis protein with HAMP domain CAC3688 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15893736 Common - Protein, containing LuxR family transcriptional regulator HTH domain CAC0445 7 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 15894346 Nonpathogen - Predicted membrane protein CAC1060 1 None None None 15893677 Common licC PTS cellobiose-specific component IIC CAC0386 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 15893672 Common - Methyl-accepting chemotaxis protein CAC0381 104 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894684 Common bglA Beta-glucosidase CAC1405 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15894204 Common - and cellulose-binding endoglucanase family 9; CelL ortholog; dockerin domain CAC0917 17 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 15895494 Common - Enzyme of ILVE/PABC family (branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase) CAC2226 175 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15894253 Common - Predicted membrane protein CAC0966 2 None None None 15896582 Common - ATPase component of ABC transporter (two ATPase domains) CAC3339 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15895990 Common - hypothetical protein CAC2733 3 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15894666 Common - Membrane associated chemotaxis sensory transducer protein (MSP domain and HAMP domain) CAC1387 142 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15896383 Common rplC 50S ribosomal protein L3 CAC3133 248 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 15895199 Nonpathogen - hypothetical protein CAC1926 1 None None None 15895695 Common greA Transcription elongation factor, greA CAC2430 182 COG0782 GreA, Transcription elongation factor Transcription 15894446 Nonpathogen - hypothetical protein CAC1163 1 None None None 15895586 Nonpathogen - hypothetical protein CAC2319 1 None None None 15893333 Common - Serine/threonine phosphatase (inactivated protein) CAC0035 132 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 15893710 Nonpathogen - Predicted membrane protein CAC0419 1 None None None 15893872 Common - CBIK protein (chain A, anaerobic cobalt chelatase) CAC0583 23 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 15893413 Common 121 protein cheY homolog CAC0117 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 15895181 Nonpathogen - hypothetical protein CAC1907 1 None None None 15896278 Common - Protein from GDSL (phospholipase B) family of lipolitic enzyme CAC3026 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15896712 Common - Predicted MDR-type permease CAC3474 200 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15896125 Common atpB F0F1 ATP synthase subunit A CAC2871 205 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 15893746 Common - hypothetical protein CAC0455 3 None None None 15895683 Nonpathogen - hypothetical protein CAC2417 1 None None None 15893511 Common - Uracyl DNA glycosilase CAC0219 145 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 15896846 Nonpathogen - hypothetical protein CAC3612 1 None None None 15896629 Common - Methyl-accepting chemotaxis protein CAC3388 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15894660 Common cbiJ/cobK cobalt-precorrin-6x reductase CAC1381 38 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 15896402 Common - RRNA methylase, YACO B.subtilis ortholog CAC3154 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15894272 Common - ABC transporter, permease component CAC0985 122 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 15894001 Common eno phosphopyruvate hydratase CAC0713 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 15896650 Common alsR Transcriptional regulators, LysR family CAC3409 192 COG0583 LysR, Transcriptional regulator Transcription 15895641 Common oppC Oligopeptide ABC-type transporter, permease component OPPC CAC2374 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15895713 Common - NAD(FAD)-dependent dehydrogenase, NirB-family (N-terminal domain) CAC2448 184 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 15893722 Common - Hypothetical protein, YitT family CAC0431 80 COG1284 COG1284, Uncharacterized conserved protein Function unknown 15895621 Common - Nifs family aminotransferase CAC2354 241 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15894938 Common - Predicted secreted nucleic acid binding protein CAC1661 1 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 15895285 Nonpathogen - hypothetical protein CAC2015 1 None None None 15894154 Common - Putative permease, ortholog yfkN B.subtilis CAC0867 1 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15893978 Common - Endoglucanase, aminopeptidase M42 family CAC0690 85 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 15895936 Common - hypothetical protein CAC2678 2 None None None 15894676 Common - Predicted hydrolase of PHP superfamily CAC1397 217 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15895243 Common - Predicted membrane protein CAC1972 2 None None None 15893797 Common - Penicillin-binding protein CAC0506 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15893968 Common - Predicted membrane protein CAC0680 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 15896471 Common purR purine operon repressor CAC3224 68 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15895630 Common - Uncharacterized protein, YtxC B.subtilis homolog CAC2363 13 None None None 15896109 Nonpathogen - Predicted membrane protein CAC2855 1 None None None 15895289 Common - Malonyl CoA-acyl carrier protein transacylase CAC2019 135 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 15893573 Common - Molybdate-binding periplasmic protein CAC0281 121 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 15895219 Nonpathogen - Phage related transcriptional regulator (Xre family) CAC1946 1 None None None 15894159 Common - Xanthine permease CAC0872 136 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15893518 Common - ABC transporter, ATP-binding protein CAC0226 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15894709 Common - Transcriptional regulators of sugar metabolism (deoR family) CAC1430 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15895021 Common - Predicted Zn-finger-like protein, possible nucleic acid binding CAC1744 42 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 15896811 Common acp Acyl Carrier Protein, ACP CAC3577 205 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15894512 Nonpathogen - Hypothetical protein, CF-34 family(identical) CAC1229 1 None None None 15895803 Nonpathogen - Reductase/isomerase/elongation factor common domain CAC2541 1 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 15895462 Common - Predicted nucleoside-diphosphate sugar epimerase CAC2194 210 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15896504 Nonpathogen - Predicted membrane protein; CF_1 family CAC3259 1 None None None 15894628 Common galM Aldose-1-epimerase CAC1349 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 15894236 Common - Predicted transcriptional regulator CAC0949 25 COG1695 COG1695, Predicted transcriptional regulators Transcription 15895085 Common - Uncharacterized conserved protein, YLMC B.subtilis ortholog CAC1809 9 COG1873 COG1873, Uncharacterized conserved protein Function unknown 15895634 Common - Uncharacterized protein containing predicted cell adhesion domain and ChW-repeats CAC2367 39 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15896670 Common - Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) CAC3429 225 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15893756 Common - Predicted transcriptional regulator, dicA/hipB/ansR family CAC0465 2 None None None 15893704 Common - Uncharacterized small conserved protein, homolog of YUKE/YFJA CAC0413 3 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 15895758 Common - Phospholipase C family protein CAC2493 1 None None None 15894249 Common - UDP-N-acetylmuramyl tripeptide synthetase CAC0962 48 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15894863 Common - MDR-type permease CAC1585 72 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 15894037 Common - hypothetical protein CAC0750 2 None None None 15896020 Common - Similar to uncharacterized domain of sensory transducer protein CAC2765 6 None None None 15894110 Common - Predicted membrane protein CAC0823 57 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15895214 Common abrB Transcription regulator AbrB CAC1941 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 15896191 Nonpathogen - hypothetical protein CAC2938 3 COG5083 SMP2, Uncharacterized protein involved in plasmid maintenance General function prediction only 15896439 Common - Uncharacterized conserved protein, containing ClpE-like Zn-zinger domain; YACH B.subtilis ortholog CAC3191 22 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 15894244 Common - Xre family DNA-binding domain and TPR-repeat-containing protein CAC0957 21 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 15896677 Common - Probable alpha-arabinofuranosidase CAC3436 29 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 15896326 Common buk butyrate kinase CAC3075 121 COG3426 COG3426, Butyrate kinase Energy production and conversion 15896694 Common - Predicted TIM-barrel enzyme, nifR3 family CAC3454 131 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15894478 Common ligA NAD-dependent DNA ligase LigA CAC1195 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15894079 Common - D-amino acid aminotransferase CAC0792 173 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15896051 Common - MoaA/NirJ family Fe-S oxidoreductase CAC2796 198 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 15895444 Common - Glycosyltransferase CAC2175 215 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15896394 Common rplJ 50S ribosomal protein L10 CAC3146 212 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 15895903 Common carA carbamoyl phosphate synthase small subunit CAC2645 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 15894012 Common - Predicted membrane protein; CF-9 family CAC0725 4 None None None 15896398 Common secE preprotein translocase subunit SecE CAC3150 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 15894831 Common - Membrane associated sensory transduction histidine kinase (with HAMP domain) CAC1553 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15893669 Common glnQ Glutamine ABC transporter, ATP-binding protein (gene glnQ) CAC0378 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15896917 Common - Predicted membrane protein CAC3685 6 None None None 15894352 Nonpathogen - hypothetical protein CAC1066 1 None None None 15896573 Common - Cytochrome P450 family protein, YBDT B.subtilis ortholog CAC3330 21 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 15895706 Common - Ferrichrome-binding periplasmic protein CAC2441 35 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15896252 Nonpathogen - hypothetical protein CAC3000 2 None None None 15894267 Common pflB Pyruvate-formate lyase CAC0980 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 15896962 Common spoOJ Stage 0 sporulation J, ParB family of DNA-binding proteins CAC3731 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 15894810 Common - Protein containing ChW-repeats CAC1532 7 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15894388 Nonpathogen - Possible metal-binding domain, related to a correspondent domain of site-specific recombinase CAC1103 1 None None None 15894123 Common - Putative beta-D-galactosidase CAC0836 34 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 15894719 Nonpathogen - hypothetical protein CAC1440 1 None None None 15896451 Common - Cell cycle protein MesJ ortholog, ATPase of the PP-loop superamily CAC3204 209 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15893458 Common - ABC transporter, ATP binding-protein CAC0164 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15895895 Common lonA ATP-dependent Lon protease CAC2637 209 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 15896775 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CAC3539 217 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 15895438 Common - UDP-galactopyranose mutase CAC2169 58 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 15896706 Common - Uncharacterized conserved protein, phnB family CAC3467 67 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 15893507 Common - Endoglucanase, aminopeptidase M42 family CAC0214 82 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 15896198 Common - glycerate dehydrogenase CAC2945 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15896664 Common - Acetyltransferase (ribosomal protein N-acetylase subfamily) CAC3423 39 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15895162 Common - hypothetical protein CAC1887 2 None None None 15896892 Common - S-adenosylmethionine-dependent methyltransferase CAC3659 35 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 15893545 Common nifH Nitrogenase iron protein (nitrogenase component II) gene nifH CAC0253 87 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 15896652 Common - Homolog of plant auxin-responsive GH3-like protein CAC3411 17 None None None 15896833 Nonpathogen - hypothetical protein CAC3599 1 None None None 15894954 Common - Predicted permease CAC1677 192 COG0628 PerM, Predicted permease General function prediction only 15895870 Common xylB Xylulose kinase CAC2612 180 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15894890 Common - Probable cation efflux pump, multidrug resistance protein (FS) CAC1612 40 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15895391 Common - hypothetical protein CAC2122 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 15893450 Common MtlR Putative regulator of the PTS system for mannitol (gene MltR) CAC0155 33 COG3711 BglG, Transcriptional antiterminator Transcription 15896047 Common - Uncharcterized conserved membrane protein, YXAI B.subtilis homolog CAC2792 5 COG1714 COG1714, Predicted membrane protein/domain Function unknown 15894823 Common deoC Deoxyribose-phosphate aldolase CAC1545 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 15896933 Nonpathogen - Hypothetical protein, CF-7 family CAC3702 1 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 15894453 Common xerC site-specific tyrosine recombinase XerC CAC1170 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15895431 Common fliF flagellar MS-ring protein CAC2162 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 15896749 Common - AraC-type DNA-binding domain-containing protein CAC3512 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15896224 Common thiI Thiamine biosynthesis enzyme, THII CAC2971 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 15895028 Common smc Chromosome segregation SMC protein, ATPase CAC1751 200 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15893699 Common - DNA segregation ATP-ase FtsK/SpoIIIE (three ATPase), contains FHA domain CAC0408 200 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15895166 Common - hypothetical protein CAC1892 5 None None None 15894277 Common gltX Glutamyl-tRNA synthetase CAC0990 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15894762 Common - Predicted transcriptional regulator CAC1483 144 COG1733 COG1733, Predicted transcriptional regulators Transcription 15893613 Common - Response regulator (CheY-like domain, HTH domain) CAC0321 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15896041 Common - Uncharacterized conserved protein, YQGV B.subtilis ortholog CAC2786 44 COG0011 COG0011, Uncharacterized conserved protein Function unknown 15893427 Nonpathogen - hypothetical protein CAC0132 1 None None None 15896469 Common gcaD UDP-N-acetylglucosamine pyrophosphorylase CAC3222 238 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 15894588 Nonpathogen - hypothetical protein CAC1306 1 None None None 15895766 Common - Membrane protein, predicted transporter of cations and cationic drugs CAC2501 2 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 15894984 Common - Permease component of ATP-dependent phosphate uptake system CAC1707 225 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 15895761 Common - Predicted phosphatase of HAD hydrolase superfamily CAC2496 14 COG0546 Gph, Predicted phosphatases General function prediction only 15894539 Common rplU 50S ribosomal protein L21 CAC1257 110 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 15894898 Common - Small acid-soluble spore protein CAC1620 5 None None None 15893925 Common tyrS tyrosyl-tRNA synthetase CAC0637 225 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15893554 Common - Tryptophan-rich possible sensory protein, TSPO homolog CAC0262 59 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 15895202 Nonpathogen - hypothetical protein CAC1929 1 None None None 15894532 Common minD Septum site-determining protein MinD, ATPase CAC1249 173 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 15894522 Common - Predicted membrane protein CAC1239 2 None None None 15893720 Common - Glicerol-3-phosphate ABC-transporter, periplasmic component CAC0429 121 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15893769 Common - hypothetical protein CAC0478 40 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 15896897 Common - Predicted flavodoxin CAC3664 32 COG0716 FldA, Flavodoxins Energy production and conversion 15893729 Common - Predicted metal-binding protein CAC0438 1 None None None 15895172 Nonpathogen - hypothetical protein CAC1898 1 None None None 15895194 Nonpathogen - Zn-finger containing protein CAC1920 1 None None None 15894131 Common - Barstar-like protein ribonuclease (barnase) inhibitor CAC0844 8 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 15894887 Common - Zn-finger containing protein CAC1609 4 None None None 15895776 Nonpathogen - Predicted membrane protein CAC2511 1 None None None 15896091 Common - Zn-binding lipoprotein related (surface adhesin A), ADHS CAC2836 64 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15894877 Common - Predicted membrane protein CAC1599 5 None None None 15893853 Common - Predicted membrane protein CAC0563 3 None None None