Escherichia coli O157:H7 str. Sakai, complete genome NC_002695 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 15833355 Common - ClpXP protease specificity-enhancing factor ECs4101 64 COG2969 SspB, Stringent starvation protein B General function prediction only 15833996 Common - predicted hydrolase ECs4742 64 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15829647 Common - cyanate hydratase ECs0393 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 15833287 Common - hypothetical protein ECs4033 58 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 38703974 Common - small toxic polypeptide ECs5440 1 None None None 15830401 Common - hypothetical protein ECs1147 102 COG0348 NapH, Polyferredoxin Energy production and conversion 15831364 Common - putative outer membrane protein ECs2110 28 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15833040 Common - chromosome replication initiation inhibitor protein ECs3786 79 COG0583 LysR, Transcriptional regulator Transcription 15833154 Common - hypothetical protein ECs3900 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15834146 Common - putative amino acid amidohydrolase ECs4892 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 15832493 Pathogen - hypothetical protein ECs3239 1 None None None 15829595 Common - hypothetical protein ECs0341 3 None None None 15829893 Common - putative aminotransferase ECs0639 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15831726 Common - protease 4 ECs2472 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 162139790 Common - putative voltage-gated ClC-type chloride channel ClcB ECs2298 136 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 15831672 Common - vtamin B12-transporter permease ECs2418 191 COG4139 BtuC, ABC-type cobalamin transport system, permease component Coenzyme metabolism 15831813 Common purT phosphoribosylglycinamide formyltransferase 2 ECs2559 196 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 15830852 Common - putative terminase large subunit ECs1598 47 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 15834104 Common glpX fructose 1,6-bisphosphatase II ECs4850 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 15830442 Pathogen - hypothetical protein ECs1188 2 None None None 15830056 Pathogen - hypothetical protein ECs0802 1 None None None 15830641 Common - hypothetical protein ECs1387 17 COG1475 Spo0J, Predicted transcriptional regulators Transcription 15832465 Common - hypothetical protein ECs3211 147 COG0730 COG0730, Predicted permeases General function prediction only 15832638 Common - putative anaerobic dimethyl sulfoxide reductase chain A precursor ECs3384 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15831799 Common yebU rRNA (cytosine-C(5)-)-methyltransferase RsmF ECs2545 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 15831777 Common - L-serine deaminase ECs2523 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 15831211 Common - hypothetical protein ECs1957 7 None None None 15832170 Common - putative chaperone ECs2916 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15831218 Common - putative endolysin ECs1964 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15833783 Common - glutamate transport protein ECs4529 53 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 15830152 Common - hypothetical protein ECs0898 11 None None None 15833327 Common - hypothetical protein ECs4073 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 15833885 Common - predicted lipoproteinC ECs4631 6 None None None 15831951 Common - hypothetical protein ECs2697 50 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 15833171 Common - putative ferrichrome iron receptor precursor ECs3917 117 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 15831935 Common fliJ flagellar biosynthesis chaperone ECs2681 39 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 162139719 Common rimM 16S rRNA-processing protein ECs3471 181 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 15833994 Common - hypothetical protein ECs4740 33 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 15831484 Pathogen - hypothetical protein ECs2230 1 None None None 15832016 Common - putative phage replication protein ECs2762 5 None None None 15832326 Common - putative ATP-binding component of a transport system ECs3072 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 15831874 Common - putative transcriptional regulator ECs2620 13 None None None 15834202 Pathogen - hypothetical protein ECs4948 1 None None None 15832886 Common - putative kinase ECs3632 171 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15830055 Pathogen - excisionase ECs0801 1 None None None 15832762 Common - hypothetical protein ECs3508 4 None None None 15833085 Common - coproporphyrinogen III oxidase ECs3831 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 38704100 Common - cysteine desulfurase ECs3396 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 15829346 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase ECs0092 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15831425 Pathogen - putative minor tail protein ECs2171 4 None None None 15831464 Common - hypothetical protein ECs2210 4 None None None 15833950 Common - putative transport protein ECs4696 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832404 Common - naphthoate synthase ECs3150 178 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 15831312 Common - putative transferase ECs2058 44 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15833017 Common prfB peptide chain release factor 2 ECs3763 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 162139733 Common - acetate operon transcriptional repressor IclR ECs4936 124 COG1414 IclR, Transcriptional regulator Transcription 162139712 Common - hypothetical protein ECs1839 222 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 162139799 Common - 23S rRNA pseudouridine synthase E ECs1607 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15829319 Common araD L-ribulose-5-phosphate 4-epimerase ECs0065 115 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 15830884 Common - terminase large subunit ECs1630 36 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 15832834 Common - formate hydrogenlyase subunit-7 component B ECs3580 142 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15830426 Pathogen - hypothetical protein ECs1172 1 None None None 15830431 Pathogen - Kil protein ECs1177 2 None None None 15830591 Common - hypothetical protein ECs1337 17 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833160 Common - hypothetical protein ECs3906 26 COG3111 COG3111, Uncharacterized conserved protein Function unknown 15830341 Common - putative transcriptional regulator ECs1087 24 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15833769 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase ECs4515 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism 15833525 Common - putative ATP binding protein of ABC transporter ECs4271 90 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 15829586 Common - hypothetical protein ECs0332 48 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 15833557 Common livM leucine/isoleucine/valine transporter permease subunit ECs4303 130 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 15830114 Common - molybdenum cofactor biosynthesis protein B ECs0860 187 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 15831679 Common infC translation initiation factor IF-3 ECs2425 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 15832914 Common - L-fuculose phosphate aldolase ECs3660 156 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 15834033 Common - molybdopterin-guanine dinucleotide biosynthesis protein B ECs4779 98 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 15830202 Common - predicted lipoprotein ECs0948 9 None None None 15833068 Common - arginine decarboxylase ECs3814 115 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 15832021 Common - hypothetical protein ECs2767 4 None None None 15831008 Common - intracellular septation protein A ECs1754 85 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 15831705 Common - succinylarginine dihydrolase ECs2451 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 15831418 Common - putative minor tail protein ECs2164 14 COG4672 gp18, Phage-related protein Function unknown 15830092 Common - putative minor tail protein ECs0838 12 COG4718 COG4718, Phage-related protein Function unknown 15829415 Common - hypothetical protein ECs0161 129 COG2860 COG2860, Predicted membrane protein Function unknown 15831627 Common - hypothetical protein ECs2373 28 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15833468 Common - peptidyl-prolyl cis-trans isomerase A (rotamase A) ECs4214 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 15831982 Pathogen - putative minor tail protein ECs2728 3 None None None 15832350 Common - assembly protein for periplasmic nitrate reductase ECs3096 21 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 15834339 Common - putative transcriptional regulator ECs5085 112 COG2188 PhnF, Transcriptional regulators Transcription 15829356 Common secA preprotein translocase subunit SecA ECs0102 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 15830253 Common - hypothetical protein ECs0999 61 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 15831496 Common - putative tail assembly chaperone ECs2242 4 None None None 38704110 Common - hypothetical protein ECs3474 58 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 15830283 Common - dihydroorotate dehydrogenase 2 ECs1029 226 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 15830710 Common flgG flagellar basal body rod protein FlgG ECs1456 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15833960 Common - threonine dehydratase ECs4706 221 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 15830419 Pathogen - hypothetical protein ECs1165 1 None None None 162139726 Common - NTPase ECs5352 35 COG1986 COG1986, Uncharacterized conserved protein Function unknown 15832158 Common - putative transcriptional regulator ECs2904 126 COG2188 PhnF, Transcriptional regulators Transcription 15832676 Common - putative 2-component sensor protein ECs3422 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15831047 Common - major head protein/prohead protease ECs1793 23 COG3740 COG3740, Phage head maturation protease General function prediction only 15834563 Common - hypothetical protein ECs5309 72 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15832554 Common murP N-acetylmuramic acid phosphotransfer permease ECs3300 47 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15830756 Common - putative excisionase ECs1502 4 None None None 15832616 Common purN phosphoribosylglycinamide formyltransferase ECs3362 222 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 15833178 Pathogen - hypothetical protein ECs3924 2 None None None 15832335 Common - putative ATP-binding component of a transport system ECs3081 28 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15831501 Common - hypothetical protein ECs2247 4 None None None 15831596 Common - endonuclease III ECs2342 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 15833871 Common - hypothetical protein ECs4617 19 COG2149 COG2149, Predicted membrane protein Function unknown 162139748 Common - 2-hydroxyacid dehydrogenase ECs4438 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15834457 Common - toxin ChpB ECs5203 35 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 15830192 Common - hypothetical protein ECs0938 9 None None None 15831167 Common - hypothetical protein ECs1913 6 None None None 15830813 Pathogen - putative tail assembly protein ECs1559 4 COG4723 COG4723, Phage-related protein, tail component Function unknown 15829301 Common - putative ferredoxin ECs0047 35 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 15832095 Common - perosamine synthetase ECs2841 203 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 38704128 Common - hypothetical protein ECs3811 117 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 38704220 Common thiF thiamine biosynthesis protein ThiF ECs4915 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 15833894 Common - putative inner membrane protein translocase component YidC ECs4640 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 15830008 Common - succinyl-CoA synthetase subunit alpha ECs0754 216 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 15832391 Common - competence damage-inducible protein A ECs3137 140 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 15830034 Common - zinc transporter ZitB ECs0780 178 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 15832804 Common - glutamate--cysteine ligase ECs3550 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 15830282 Common - hypothetical protein ECs1028 6 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 38704162 Common - nitrite transporter NirC ECs4218 90 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 15830438 Common - hypothetical protein ECs1184 2 None None None 15830754 Common potC spermidine/putrescine ABC transporter membrane protein ECs1500 217 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 15834243 Common - tail fiber ECs4989 9 None None None 15834551 Common - hypothetical protein ECs5297 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 15830819 Common - putative transposase ECs1565 25 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829536 Common - hypothetical protein ECs0282 6 None None None 15831403 Common - hypothetical protein ECs2149 136 COG1802 GntR, Transcriptional regulators Transcription 15829717 Common - hypothetical protein ECs0463 26 None None None 15834312 Common - formate-dependent nitrite reductase complex subunit NrfG ECs5058 47 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 15831474 Common - putative transposase ECs2220 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833493 Common nudE ADP-ribose diphosphatase NudE ECs4239 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 38704113 Common - DNA-binding transcriptional regulator CsiR ECs3525 117 COG1802 GntR, Transcriptional regulators Transcription 15831782 Common - mannose-specific PTS enzyme IIC ECs2528 37 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 38704248 Common - hypothetical protein ECs5228 79 COG1309 AcrR, Transcriptional regulator Transcription 15831069 Pathogen - hypothetical protein ECs1815 2 None None None 15832106 Common - putative UDP-glucose lipid carrier transferase ECs2852 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 15830486 Common - hypothetical protein ECs1232 5 None None None 15830217 Common - hypothetical protein ECs0963 21 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 15830879 Common - Bor precursor ECs1625 6 None None None 38704029 Common - transcriptional activator FlhD ECs2602 27 None None None 38703978 Common - putative oxidoreductase ECs2053 102 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 15833563 Common - periplasmic binding protein of high-affinity amino acid transport system ECs4309 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 15830475 Common - putative portal protein ECs1221 11 None None None 15830212 Common - HCP oxidoreductase, NADH-dependent ECs0958 125 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 15833053 Common - hypothetical protein ECs3799 16 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 15832481 Common - long-chain fatty acid outer membrane transporter ECs3227 80 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 162139811 Common - putative 3-hydroxyphenylpropionic transporter MhpT ECs0408 150 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15834208 Common - hypothetical protein ECs4954 2 None None None 15831654 Common aroD 3-dehydroquinate dehydratase ECs2400 55 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 15831196 Common - regulatory protein ECs1942 4 None None None 15830247 Common cmk cytidylate kinase ECs0993 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 15832117 Common - putative colanic acid biosynthesis acetyltransferase WcaB ECs2863 197 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 15831888 Common - putative plasmid partition protein ECs2634 12 None None None 15830606 Common - TerA ECs1352 25 COG4110 COG4110, Uncharacterized protein involved in stress response General function prediction only 15831401 Common - dipeptidyl carboxypeptidase II ECs2147 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 15831506 Common - putative terminase small subunit ECs2252 4 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 15832291 Common - hypothetical protein ECs3037 4 None None None 15830935 Common nhaB sodium/proton antiporter ECs1681 31 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 15834227 Common - putative protease protein ECs4973 17 COG4388 COG4388, Mu-like prophage I protein General function prediction only 38703901 Common - macrolide transporter subunit MacA ECs0964 174 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15832792 Common - ribonucleotide-diphosphate reductase subunit alpha ECs3538 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15830808 Common - putative minor tail protein ECs1554 5 COG4718 COG4718, Phage-related protein Function unknown 15834065 Common - putative acetyltransferase ECs4811 48 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 15833001 Common - carbamate kinase ECs3747 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 15829463 Common - hypothetical protein ECs0209 55 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15833097 Common - integrase ECs3843 105 COG0582 XerC, Integrase DNA replication, recombination, and repair 15832698 Common - neutral amino-acid efflux protein ECs3444 88 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 15830384 Common - hydrogenase 1 b-type cytochrome subunit ECs1130 46 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 15832783 Common - hypothetical protein ECs3529 63 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15834027 Common fadA 3-ketoacyl-CoA thiolase ECs4773 179 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 15833623 Common - putative methyltransferase ECs4369 54 None None None 15830920 Common - putative transposase ECs1666 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829340 Common mraW S-adenosyl-methyltransferase MraW ECs0086 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 15830279 Common - FimH-like protein ECs1025 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15833127 Common - bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase ECs3873 52 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 38703935 Common - hypothetical protein ECs1489 103 COG1309 AcrR, Transcriptional regulator Transcription 15831427 Pathogen - putative DNA-packaging protein ECs2173 2 None None None 15829304 Common - glutathione-regulated potassium-efflux system protein KefC ECs0050 196 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15833090 Common trmB tRNA (guanine-N(7))-methyltransferase ECs3836 177 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 15833785 Common - hypothetical protein ECs4531 13 None None None 15830064 Common - NinE ECs0810 2 None None None 38703855 Common - hypothetical protein ECs5376 1 None None None 38704098 Common - enhanced serine sensitivity ECs3388 13 None None None 15830945 Common - hypothetical protein ECs1691 15 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 15833272 Common - N-acetylgalactosamine-specific PTS system transporter subunit IIB ECs4018 38 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 15831516 Common - hypothetical protein ECs2262 3 None None None 15832004 Common - antiterminator ECs2750 6 None None None 15829430 Common - undecaprenyl pyrophosphate synthase ECs0176 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15830810 Pathogen - putative regulatory protein ECs1556 3 COG4691 StbC, Plasmid stability protein General function prediction only 15833010 Common - guanine deaminase ECs3756 159 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15833922 Pathogen - hypothetical protein ECs4668 2 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15829385 Common - putative ATP-binding component of a transport system ECs0131 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15833315 Common - D-alanyl-D-alanine carboxypeptidase/endopeptidase ECs4061 110 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 15832105 Common - colanic acid exporter ECs2851 112 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15834502 Common - hypothetical protein ECs5248 21 COG4333 COG4333, Uncharacterized protein conserved in bacteria Function unknown 15830131 Common dinG ATP-dependent DNA helicase DinG ECs0877 126 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 15829869 Common - putative transport ECs0615 95 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 38704153 Common - regulator of ftsI ECs4123 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 15830621 Pathogen - hypothetical protein ECs1367 1 None None None 15832926 Common - hypothetical protein ECs3672 214 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 15829749 Common - peptidyl-prolyl cis-trans isomerase (rotamase D) ECs0495 161 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15829993 Common - endonuclease VIII ECs0739 122 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 15833023 Common - hypothetical protein ECs3769 50 COG2938 COG2938, Uncharacterized conserved protein Function unknown 15829698 Common rdgC recombination associated protein ECs0445 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 15830001 Common sdhD succinate dehydrogenase cytochrome b556 small membrane subunit ECs0747 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 15829427 Common pyrH uridylate kinase ECs0173 237 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 38704136 Common - putative ARAC-type regulatory protein ECs3895 136 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15834352 Common - putative ARAC-type regulatory protein ECs5098 9 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15831866 Common - hypothetical protein ECs2612 5 None None None 15834537 Common - DNA-binding transcriptional repressor ECs5283 137 COG2186 FadR, Transcriptional regulators Transcription 15829705 Common - branched chain amino acid transport system II carrier protein ECs0451 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 15829444 Common tilS tRNA(Ile)-lysidine synthetase ECs0190 195 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15833971 Common - UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase ECs4717 171 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15833367 Common - p-hydroxybenzoic acid efflux subunit AaeB ECs4113 46 COG1289 COG1289, Predicted membrane protein Function unknown 15834415 Common - hypothetical protein ECs5161 4 COG5463 COG5463, Predicted integral membrane protein Function unknown 38703908 Common - sulfurtransferase TusE ECs1053 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 15831126 Common - hypothetical protein ECs1872 5 None None None 15832199 Common - putative tail assembly protein ECs2945 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 15833669 Common - hypothetical protein ECs4415 8 None None None 15834245 Pathogen - putative tail fiber protein ECs4991 2 None None None 15832656 Common - putative 3-phenylpropionic acid transporter ECs3402 75 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832685 Common recO DNA repair protein RecO ECs3431 83 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15830209 Common - putative dTDP-glucose enzyme ECs0955 129 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15830760 Common - putative phage repressor ECs1506 4 None None None 15833847 Pathogen - hypothetical protein ECs4593 1 None None None 15834116 Common - primosome assembly protein PriA ECs4862 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 15832938 Common thyA thymidylate synthase ECs3684 139 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 15830264 Common - hypothetical protein ECs1010 221 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15830715 Common flgL flagellar hook-associated protein FlgL ECs1461 104 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15829963 Common - N-acetyl glucosamine specific PTS system components IIABC ECs0709 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15834328 Common - putative histidine protein kinase ECs5074 213 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 15832389 Common - putative racemase ECs3135 97 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 15830908 Common - hypothetical protein ECs1654 38 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 15833978 Common - TDP-4-oxo-6-deoxy-D-glucose transaminase ECs4724 201 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15834138 Common - hypothetical protein ECs4884 53 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15834133 Common - PTS system fructose-like IIB component 1 ECs4879 68 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 15830775 Pathogen - hypothetical protein ECs1521 5 None None None 15831610 Common - hypothetical protein ECs2356 174 COG4989 COG4989, Predicted oxidoreductase General function prediction only 15832508 Common - formyl-coenzyme A transferase ECs3254 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 15829451 Common - hypothetical protein ECs0197 95 COG1720 COG1720, Uncharacterized conserved protein Function unknown 15833543 Common - putative regulator ECs4289 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15834094 Common fieF ferrous iron efflux protein F ECs4840 209 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 15833157 Common - DNA topoisomerase IV subunit A ECs3903 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15832307 Common - putative transport system permease protein ECs3053 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 15831941 Common fliP flagellar biosynthesis protein FliP ECs2687 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 15830963 Common - peptidyl-tRNA hydrolase ECs1709 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 15830803 Common - putative major tail subunit ECs1549 6 None None None 162139720 Common - hypothetical protein ECs3780 37 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 15830553 Common - putative integrase ECs1299 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 15831565 Common - putative arginine/ornithine antiporter ECs2311 132 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15829281 Common - hypothetical protein ECs0027 3 None None None 15833670 Common - putative protease ECs4416 16 None None None 15831286 Common - ribosomal-protein-serine N-acetyltransferase ECs2032 12 None None None 15832561 Common - coproporphyrinogen III oxidase ECs3307 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 15832498 Common - sucrose operon repressor ECs3244 125 COG1609 PurR, Transcriptional regulators Transcription 15832628 Common - outer membrane protein assembly complex subunit YfgL ECs3374 127 COG1520 COG1520, FOG: WD40-like repeat Function unknown 15832745 Common - putative transposase ECs3491 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831631 Common - hypothetical protein ECs2377 16 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 15832450 Common - amidophosphoribosyltransferase ECs3196 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 15830369 Common - putative minor tail protein ECs1115 13 COG4718 COG4718, Phage-related protein Function unknown 15830613 Pathogen - hypothetical protein ECs1359 2 None None None 15834265 Common - hypothetical protein ECs5011 14 None None None 15831970 Pathogen - hypothetical protein ECs2716 1 None None None 15834154 Common birA biotin--protein ligase ECs4900 231 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 15834048 Common - putative transcriptional regulator ECs4794 65 COG2188 PhnF, Transcriptional regulators Transcription 15829956 Pathogen - putative RNA ECs0702 5 None None None 15829683 Common - hypothetical protein ECs0429 6 None None None 15829810 Common - short chain dehydrogenase ECs0556 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 162139774 Common - hypothetical protein ECs3113 7 COG4685 COG4685, Uncharacterized protein conserved in bacteria Function unknown 15831156 Common - DNA-binding transcriptional dual regulator, tyrosine-binding ECs1902 173 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 15834361 Common - sensory histidine kinase DcuS ECs5107 205 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 15830652 Common - hypothetical protein ECs1398 5 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 15832535 Common - hypothetical protein ECs3281 192 COG0583 LysR, Transcriptional regulator Transcription 15830164 Common - putative transport system permease protein ECs0910 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15833296 Common - tryptophan permease ECs4042 31 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15830239 Common pflA pyruvate formate lyase-activating enzyme 1 ECs0985 108 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15833973 Common - UDP-N-acetyl glucosamine-2-epimerase ECs4719 156 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 38704090 Common - lipoprotein ECs3339 21 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 15832302 Common - lysine transporter ECs3048 169 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 15829795 Common - hypothetical protein ECs0541 186 None None None 15829860 Common - hypothetical protein ECs0606 5 COG5435 COG5435, Uncharacterized conserved protein Function unknown 15830638 Common - hypothetical protein ECs1384 59 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 15830116 Common moaD molybdopterin synthase small subunit ECs0862 79 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 15830199 Common - arginine transporter permease subunit ArtQ ECs0945 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 15832137 Common - multidrug efflux system subunit MdtB ECs2883 181 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 15831003 Common cls cardiolipin synthetase ECs1749 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15830925 Common - hypothetical protein ECs1671 7 None None None 15832162 Common - hypothetical protein ECs2908 5 None None None 15832413 Common - hypothetical protein ECs3159 7 None None None 15832516 Common - putative ARAC-type regulatory protein ECs3262 109 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15832041 Common cobS cobalamin synthase ECs2787 140 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 38704196 Common - hypothetical protein ECs4625 56 COG2985 COG2985, Predicted permease General function prediction only 15832138 Common - multidrug efflux system subunit MdtC ECs2884 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 38704216 Common - PEP-protein phosphotransferase system enzyme I ECs4877 233 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 15829985 Common - H repeat-associated protein ECs0731 34 COG5433 COG5433, Transposase DNA replication, recombination, and repair 15829481 Common - hypothetical protein ECs0227 18 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 15833944 Common - membrane-associated component of D-ribose high-affinity transport system ECs4690 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 15834473 Common - magnesium-transporting ATPase MgtA ECs5219 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 15831697 Common - N,N'-diacetylchitobiose-specific PTS system transporter subunit IIC ECs2443 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 15832213 Common - putative transposase ECs2959 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833696 Common glyS glycyl-tRNA synthetase subunit beta ECs4442 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 15833503 Common - hypothetical protein ECs4249 214 COG2183 Tex, Transcriptional accessory protein Transcription 15834376 Common - inner membrane protein YjeH ECs5122 84 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15830982 Common - nitrite extrusion protein ECs1728 71 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 15830687 Common - hypothetical protein ECs1433 137 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 15833601 Common nikE nickel transporter ATP-binding protein ECs4347 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15834541 Common - hypothetical protein ECs5287 11 COG0700 SpmB, Uncharacterized membrane protein Function unknown 15832381 Common - anaerobic glycerol-3-phosphate dehydrogenase subunit B ECs3127 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 15830900 Common - tail assembly protein ECs1646 14 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15831087 Common - tryptophan synthase subunit beta ECs1833 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 162139784 Common - hypothetical protein ECs2572 8 None None None 15829898 Common - alkyl hydroperoxide reductase subunit C ECs0644 216 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15834198 Common - putative DNA-binding protein ECs4944 21 COG3423 Nlp, Predicted transcriptional regulator Transcription 15834189 Common - regulator of acetyl CoA synthetase ECs4935 5 None None None 15832315 Common - fructose-specific PTS IIA/HPr components ECs3061 120 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 162139816 Common pcnB poly(A) polymerase I ECs0147 211 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15830717 Common - hypothetical protein ECs1463 3 None None None 15833234 Common - hypothetical protein ECs3980 10 COG4575 ElaB, Uncharacterized conserved protein Function unknown 15832120 Common - tyrosine phosphatase ECs2866 134 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 15832342 Common - heme exporter protein C ECs3088 124 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 15830788 Common - putative endopeptidase ECs1534 10 None None None 15831829 Common ntpA dATP pyrophosphohydrolase ECs2575 37 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15830557 Common - hypothetical protein ECs1303 21 None None None 15831977 Common - putative minor tail protein ECs2723 14 COG4672 gp18, Phage-related protein Function unknown 15829264 Common - hypothetical protein ECs0010 50 COG1584 COG1584, Predicted membrane protein Function unknown 15831306 Common - putative resistance protein ECs2052 111 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 15831139 Common - thiosulfate:cyanide sulfurtransferase (rhodanese) ECs1885 82 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15833293 Common - putative collagenase ECs4039 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15833791 Common - hypothetical protein ECs4537 141 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 38704229 Common - hypothetical protein ECs5582 2 None None None 15834583 Common rsmC 16S ribosomal RNA m2G1207 methyltransferase ECs5329 154 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 15831010 Common - outer membrane protein W ECs1756 71 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 15830838 Common - hypothetical protein ECs1584 26 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 15833345 Common gltB glutamate synthase subunit alpha ECs4091 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 15832033 Common - AMP nucleosidase ECs2779 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15831233 Common - hypothetical protein ECs1979 2 None None None 15832715 Pathogen - leader peptide of chorismate mutase-P-prephenate dehydratase ECs3461 1 None None None 15832111 Common - GDP-fucose synthetase chain A ECs2857 222 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15829665 Common - alcohol dehydrogenase class III ECs0411 199 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 15833226 Common - hypothetical protein ECs3972 17 None None None 15833332 Common - hypothetical protein ECs4078 25 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 15829998 Common - putative fimbrial-like protein ECs0744 14 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15831301 Common - putative transport system permease protein ECs2047 120 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 15830525 Common - hypothetical protein ECs1271 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 15830397 Pathogen - hypothetical protein ECs1143 1 None None None 15832880 Common - putative transport protein ECs3626 88 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 15832010 Common - hypothetical protein ECs2756 4 None None None 15834024 Common rfaH transcriptional activator RfaH ECs4770 38 COG0250 NusG, Transcription antiterminator Transcription 15830897 Common - tail length tape measure protein precursor ECs1643 21 COG5281 COG5281, Phage-related minor tail protein Function unknown 15833361 Common - serine endoprotease ECs4107 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15831574 Common - hypothetical protein ECs2320 19 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 15832221 Common - putative antirepressor protein ECs2967 8 None None None 15832355 Common - alkylated DNA repair protein ECs3101 57 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 15831668 Common - hypothetical protein ECs2414 8 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 38703911 Pathogen - hypothetical protein ECs5406 2 None None None 15830858 Common - hypothetical protein ECs1604 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 15831289 Common - tellurite resistance protein TehB ECs2035 52 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 15833491 Common - hypothetical protein ECs4237 10 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 15830571 Common - putative outer membrane protein ECs1317 63 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15834162 Common rplJ 50S ribosomal protein L10 ECs4908 205 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 15832996 Common - putative transcriptional regulator ECs3742 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 15831057 Common - putative tail length tape measure protein ECs1803 48 COG5281 COG5281, Phage-related minor tail protein Function unknown 15833723 Common - predicted glutathione S-transferase ECs4469 80 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15832896 Common - toxin ChpA ECs3642 50 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 15832380 Common glpA sn-glycerol-3-phosphate dehydrogenase subunit A ECs3126 163 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15832289 Common - cytidine deaminase ECs3035 33 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 15829506 Common - hypothetical protein ECs0252 34 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 15832518 Common - hypothetical protein ECs3264 90 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 15830566 Common - putative complement resistance protein precursor ECs1312 19 None None None 15832228 Pathogen - Shiga toxin I subunit A precursor ECs2974 2 None None None 15831661 Common - hypothetical protein ECs2407 33 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 15832540 Common - cysteine synthase A ECs3286 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 15833832 Pathogen - hypothetical protein ECs4578 1 None None None 15833931 Common - F0F1 ATP synthase subunit delta ECs4677 174 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 15831030 Common - hypothetical protein ECs1776 6 None None None 38704079 Common - hypothetical protein ECs3276 77 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829769 Common - acridine efflux pump ECs0515 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 15831755 Common - hypothetical protein ECs2501 77 COG3189 COG3189, Uncharacterized conserved protein Function unknown 15831050 Common - hypothetical protein ECs1796 4 None None None 15834521 Pathogen - hypothetical protein ECs5267 1 None None None 15830576 Common ureA urease subunit gamma ECs1322 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 38703852 Common rpmJ 50S ribosomal protein L36 ECs5375 61 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 15833875 Common - putative ARAC-type regulatory protein ECs4621 4 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15833215 Common - hypothetical protein ECs3961 4 None None None 15831659 Common - electron transfer flavoprotein subunit YdiR ECs2405 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 15832549 Common - sulfate/thiosulfate transporter subunit ECs3295 228 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 15833405 Common - hypothetical protein ECs4151 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 15831049 Common - putative portal protein ECs1795 64 COG4695 COG4695, Phage-related protein Function unknown 15832009 Pathogen - hypothetical protein ECs2755 1 None None None 15831341 Common - putative ATP-binding component of a transport system ECs2087 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15833474 Common - hypothetical protein ECs4220 6 None None None 15829282 Common - bifunctional riboflavin kinase/FMN adenylyltransferase ECs0028 211 COG0196 RibF, FAD synthase Coenzyme metabolism 15833459 Common - hypothetical protein ECs4205 30 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 15829928 Common - hypothetical protein ECs0674 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 15832971 Common - EprJ ECs3717 4 None None None 15832123 Common - hypothetical protein ECs2869 34 COG4679 COG4679, Phage-related protein Function unknown 15829806 Common - putative protease ECs0552 220 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15831584 Common - putative aminotrasferase ECs2330 224 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 15831619 Common - superoxide dismutase ECs2365 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 15830970 Common prfA peptide chain release factor 1 ECs1716 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 15829569 Common - hypothetical protein ECs0315 75 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 15831890 Common - putative transposase ECs2636 134 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830745 Common - hypothetical protein ECs1491 83 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15831105 Common - phosphatidylglycerophosphatase B ECs1851 31 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15832985 Common - EivA ECs3731 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 15832528 Common - hypothetical protein ECs3274 6 None None None 15832776 Common gabD succinate-semialdehyde dehydrogenase I ECs3522 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15829655 Common - DNA-binding transcriptional activator, 3HPP-binding ECs0401 92 COG1414 IclR, Transcriptional regulator Transcription 15829372 Common aceE pyruvate dehydrogenase subunit E1 ECs0118 155 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 15834005 Common - phospholipase A ECs4751 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 15832368 Common - DNA gyrase subunit A ECs3114 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15831222 Common - putative DNase ECs1968 5 COG1403 McrA, Restriction endonuclease Defense mechanisms 15833690 Common - biotin sulfoxide reductase ECs4436 179 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15829676 Common tauD taurine dioxygenase ECs0422 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 15832379 Common glpT sn-glycerol-3-phosphate transporter ECs3125 84 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15829825 Pathogen - hypothetical protein ECs0571 2 None None None 38704243 Common ulaA ascorbate-specific PTS system enzyme IIC ECs5169 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 15830704 Common flgA flagellar basal body P-ring biosynthesis protein FlgA ECs1450 28 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 15833015 Common - isopentenyl-diphosphate delta-isomerase ECs3761 52 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 38704061 Common - hypothetical protein ECs3066 15 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15832709 Common - protein disaggregation chaperone ECs3455 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15832799 Common - predicted inner membrane protein ECs3545 8 None None None 15830228 Common - leucine-responsive transcriptional regulator ECs0974 157 COG1522 Lrp, Transcriptional regulators Transcription 15833735 Common - L-lactate permease ECs4481 102 COG1620 LldP, L-lactate permease Energy production and conversion 15830890 Pathogen - DNA packaging protein ECs1636 2 None None None 15832406 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase ECs3152 104 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 15834533 Common - D-mannose specific adhesin ECs5279 6 None None None 15832666 Common - putative transport system permease protein ECs3412 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 38704004 Common - cysteine desulfurase activator complex subunit SufB ECs2390 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 15834514 Common - hypothetical protein ECs5260 109 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 15833412 Common - hypothetical protein ECs4158 26 None None None 15830867 Pathogen - Ren protein ECs1613 1 None None None 15829991 Common - putative carboxylase ECs0737 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 15831292 Common - hypothetical protein ECs2037 105 COG1396 HipB, Predicted transcriptional regulators Transcription 15830087 Pathogen - putative minor tail protein ECs0833 4 None None None 15833809 Pathogen - EspD ECs4555 1 COG5613 COG5613, Uncharacterized conserved protein Function unknown 38703985 Common - hypothetical protein ECs2081 58 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 15833816 Pathogen - hypothetical protein ECs4562 2 None None None 15833529 Common glgC glucose-1-phosphate adenylyltransferase ECs4275 175 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 15831144 Common - putative binding-protein dependent transport protein ECs1890 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 15830799 Common - hypothetical protein ECs1545 4 None None None 15830142 Common glnP glutamine ABC transporter permease protein ECs0888 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15830672 Common - hypothetical protein ECs1418 1 None None None 38704130 Common - hypothetical protein ECs3824 130 COG1678 COG1678, Putative transcriptional regulator Transcription 15832270 Common - putative ATP-binding component of a transport system ECs3016 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 15829436 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase ECs0182 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 38703873 Common - putative thioredoxin-like protein ECs0555 214 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 38704205 Common - hypothetical protein ECs4776 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 15831432 Pathogen - putative head-to-tail joining protein ECs2178 4 None None None 15833706 Common - putative regulator of xyl operon ECs4452 121 COG1609 PurR, Transcriptional regulators Transcription 38704129 Common - hypothetical protein ECs3822 193 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 15833657 Common - putative transport protein ECs4403 125 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15833441 Pathogen - hypothetical protein ECs4187 1 None None None 38704065 Common - hypothetical protein ECs3112 13 COG3234 COG3234, Uncharacterized protein conserved in bacteria Function unknown 15829522 Common - outer membrane phosphoporin protein E ECs0268 30 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 38704142 Common - glycerate kinase I ECs4002 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 15829901 Common - putative oxidoreductase ECs0647 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15829456 Common - D,D-heptose 1,7-bisphosphate phosphatase ECs0202 132 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 15833630 Common - hypothetical protein ECs4376 2 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 38704152 Common - transcriptional regulator NanR ECs4099 126 COG2186 FadR, Transcriptional regulators Transcription 38704246 Common - hypothetical protein ECs5189 141 COG1733 COG1733, Predicted transcriptional regulators Transcription 15832577 Common - hypothetical protein ECs3323 18 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 15830851 Common - putative terminase small subunit ECs1597 14 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 38703885 Common - putative DNA-binding transcriptional regulator ECs0667 99 COG0583 LysR, Transcriptional regulator Transcription 15834420 Common - predicted hydrolase ECs5166 20 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 15832841 Common - formate hydrogenlyase activator protein ECs3587 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 15831293 Common - putative collagenase ECs2039 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15829908 Common - citrate lyase alpha chain ECs0654 32 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 15833484 Common - hypothetical protein ECs4230 17 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 15830373 Pathogen - hypothetical protein ECs1119 1 None None None 15829496 Common - Rhs core protein ECs0242 48 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15830108 Common - 8-amino-7-oxononanoate synthase ECs0854 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 15833417 Common rpsM 30S ribosomal protein S13 ECs4163 245 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 15833350 Common - N-acetylmannosamine-6-phosphate 2-epimerase ECs4096 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 15829403 Common - DnaK transcriptional regulator DksA ECs0149 119 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15833356 Common sspA stringent starvation protein A ECs4102 111 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15833628 Common - arsenical pump membrane protein ECs4374 108 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 15834011 Common - hypothetical protein ECs4757 40 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15830381 Pathogen - hypothetical protein ECs1127 2 None None None 15831454 Pathogen - hypothetical protein ECs2200 2 None None None 15832674 Common - putative 2-component transcriptional regulator ECs3420 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15833464 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein ECs4210 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 15834427 Common - L-xylulose 5-phosphate 3-epimerase ECs5173 38 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 15834285 Common - tRNA-dihydrouridine synthase A ECs5031 203 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15831423 Common - hypothetical protein ECs2169 5 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15829944 Common rihA ribonucleoside hydrolase 1 ECs0690 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 15829408 Common - ferrichrome outer membrane transporter ECs0154 119 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15829778 Common - hypothetical protein ECs0524 103 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 15833700 Common - hypothetical protein ECs4446 10 COG4682 COG4682, Predicted membrane protein Function unknown 15830510 Common - hypothetical protein ECs1256 179 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15831614 Common - glyoxalase I ECs2360 127 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 15832093 Common - GDP-D-mannose dehydratase ECs2839 229 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 15831113 Common - exoribonuclease II ECs1859 192 COG4776 Rnb, Exoribonuclease II Transcription 15833835 Common - EscT ECs4581 99 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 15830021 Pathogen - hypothetical protein ECs0767 2 None None None 15829841 Common - peptidyl-prolyl cis-trans isomerase B (rotamase B) ECs0587 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 15830266 Common - outer membrane protein F ECs1012 39 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15832817 Common - DNA-bindng transcriptional repressor ECs3563 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15831524 Pathogen - hypothetical protein ECs2270 2 None None None 15831963 Common - putative sulfite oxidase subunit YedY ECs2709 125 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 15830534 Common - putative major pilin protein ECs1280 18 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832758 Common - hypothetical protein ECs3504 10 None None None 15834085 Common rhaB rhamnulokinase ECs4831 103 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15830729 Common - hypothetical protein ECs1475 183 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 15830355 Pathogen - hypothetical protein ECs1101 1 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 15832523 Common - hypothetical protein ECs3269 10 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 15832956 Common - putative transporter protein ECs3702 36 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15829338 Common - DNA-binding transcriptional regulator FruR ECs0084 122 COG1609 PurR, Transcriptional regulators Transcription 15829543 Common - putative integrase ECs0289 116 COG0582 XerC, Integrase DNA replication, recombination, and repair 15833249 Common - propionate/acetate kinase ECs3995 161 COG0282 ackA, Acetate kinase Energy production and conversion 15829519 Common - xanthine-guanine phosphoribosyltransferase ECs0265 65 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15831318 Common - 4-oxalocrotonate tautomerase ECs2064 13 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 15833608 Common - phosphotransferase system HPr enzyme ECs4354 58 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 15831775 Common - para-aminobenzoate synthase component I ECs2521 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15833480 Common - tryptophanyl-tRNA synthetase ECs4226 233 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15829712 Common yajC preprotein translocase subunit YajC ECs0458 168 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 15832824 Common - ascBF operon repressor ECs3570 127 COG1609 PurR, Transcriptional regulators Transcription 15834297 Common - hypothetical protein ECs5043 163 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 15833431 Common rpmC 50S ribosomal protein L29 ECs4177 95 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 15831744 Common - putative an aldehyde reductase ECs2490 200 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 15834360 Common - DNA-binding response regulator in two-component regulatory system with DcuS ECs5106 148 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 15833372 Common - hypothetical protein ECs4118 56 COG3164 COG3164, Predicted membrane protein Function unknown 15833618 Common - hypothetical protein ECs4364 136 COG2081 COG2081, Predicted flavoproteins General function prediction only 15830738 Common thiK thiamin kinase ECs1484 15 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 15831172 Common - putative transposase ECs1918 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830588 Pathogen - hypothetical protein ECs1334 1 None None None 38703863 Common araJ protein AraJ ECs0446 162 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830829 Common - putative DNA binding protein ECs1575 12 COG3311 AlpA, Predicted transcriptional regulator Transcription 38703845 Common - hypothetical protein ECs0126 11 None None None 15833590 Common - hypothetical membrane protein ECs4336 39 COG4258 COG4258, Predicted exporter General function prediction only 15832393 Common - hypothetical protein ECs3139 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15834304 Common - hypothetical protein ECs5050 44 COG3162 COG3162, Predicted membrane protein Function unknown 15829620 Common - hypothetical protein ECs0366 1 None None None 15832062 Common - hypothetical protein ECs2808 5 COG4917 EutP, Ethanolamine utilization protein Amino acid transport and metabolism 15831201 Pathogen - hypothetical protein ECs1947 1 None None None 15831078 Pathogen - hypothetical protein ECs1824 2 None None None 38704175 Pathogen - hypothetical protein ECs5534 1 None None None 15830954 Pathogen - hypothetical protein ECs1700 1 None None None 15831179 Common - hypothetical protein ECs1925 184 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15832294 Common mglC beta-methylgalactoside transporter inner membrane component ECs3040 126 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 38703938 Common - hypothetical protein ECs5418 2 None None None 38703897 Common - hypothetical protein ECs5400 19 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 15832584 Common - putative oxidoreductase Fe-S binding subunit ECs3330 217 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 38703952 Common - hypothetical protein ECs5426 6 None None None 15834472 Common treR trehalose repressor ECs5218 125 COG1609 PurR, Transcriptional regulators Transcription 15833510 Common - predicted gluconate transport-associated protein ECs4256 74 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 15830296 Common - SOS cell division inhibitor ECs1042 10 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 15831930 Common fliE flagellar hook-basal body protein FliE ECs2676 71 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 15832445 Common - histidine transport system membrane protein M ECs3191 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 15832208 Pathogen - putative minor tail protein ECs2954 4 None None None 15831519 Common - hypothetical protein ECs2265 15 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 15829848 Common - putative outer membrane protein ECs0594 31 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15833421 Common rpmD 50S ribosomal protein L30 ECs4167 154 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 15833071 Common - hypothetical protein ECs3817 3 None None None 15833909 Pathogen - hypothetical protein ECs4655 1 None None None 15833038 Common - D-3-phosphoglycerate dehydrogenase ECs3784 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15834161 Common rplA 50S ribosomal protein L1 ECs4907 238 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 15830188 Common - putrescine transporter subunit: periplasmic-binding component of ABC superfamily ECs0934 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15830028 Common tolA cell envelope integrity inner membrane protein TolA ECs0774 18 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15829503 Common gmhA phosphoheptose isomerase ECs0249 124 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 15830171 Common - putative dehydrogenase ECs0917 119 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 15829551 Common - putative polarity suppression protein ECs0297 4 None None None 15834608 Common - right origin-binding protein ECs5354 112 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15832735 Common - hypothetical protein ECs3481 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 15829361 Common coaE dephospho-CoA kinase ECs0107 204 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 15832822 Common - transcriptional regulatory protein ECs3568 123 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15830396 Common - putative regulator ECs1142 13 None None None 15831769 Common - putative outer membrane protein ECs2515 29 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 15833925 Common - D-fructose-6-phosphate amidotransferase ECs4671 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 15831767 Common - ribonuclease D ECs2513 120 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 15831558 Common - hypothetical protein ECs2304 13 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 162139767 Common - esterase YpfH ECs3335 55 COG0400 COG0400, Predicted esterase General function prediction only 15831014 Common - hypothetical protein ECs1760 4 None None None 15830495 Pathogen - hypothetical protein ECs1241 4 None None None 15833250 Common - anaerobically inducible L-threonine/L-serine permease ECs3996 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15832250 Common - putative single-stranded DNA binding protein ECs2996 1 None None None 15831386 Common - putative aldehyde dehydrogenase ECs2132 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15831434 Common - putative terminase small subunit ECs2180 8 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 15834336 Common - PhnI ECs5082 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 15834241 Common - hypothetical protein ECs4987 25 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 38704188 Common ligB NAD-dependent DNA ligase LigB ECs4522 217 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15834383 Common - suppressor of groEL ECs5129 119 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 15832785 Common - hypothetical protein ECs3531 13 None None None 15829572 Common - putative ferredoxin ECs0318 21 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 15831276 Common - glyceraldehyde 3-phosphate dehydrogenase C ECs2022 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15831397 Common ftrA transcriptional activator FtrA ECs2143 122 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15833709 Common avtA valine--pyruvate transaminase ECs4455 125 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 15834446 Common - PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase ECs5192 179 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 15833647 Common - multidrug resistance efflux protein MdtE ECs4393 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15833251 Common - threonine dehydratase ECs3997 206 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 15830581 Common - UreG ECs1327 149 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 15831635 Common - hypothetical protein ECs2381 153 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 38704089 Common - hypothetical protein ECs5496 11 None None None 15833902 Common - DNA-binding transcriptional regulator YidZ ECs4648 87 COG0583 LysR, Transcriptional regulator Transcription 15829557 Common - putative DNA primase ECs0303 54 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 15833240 Common - putative cytochrome ECs3986 49 COG3152 COG3152, Predicted membrane protein Function unknown 15833181 Common - hypothetical protein ECs3927 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 38704203 Common - hypothetical protein ECs5556 6 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 15833919 Common - putative fimbrial protein ECs4665 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15834061 Common - putative DEOR-type transcriptional regulator ECs4807 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15832180 Common - hypothetical protein ECs2926 2 None None None 38703994 Common - hypothetical protein ECs5451 2 None None None 15829468 Pathogen - hypothetical protein ECs0214 3 None None None 15829657 Common - 2,3-dihydroxyphenylpropionate 1,2-dioxygenase ECs0403 30 COG1355 COG1355, Predicted dioxygenase General function prediction only 15832372 Common nrdB ribonucleotide-diphosphate reductase subunit beta ECs3118 154 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 15830779 Pathogen - hypothetical protein ECs1526 1 None None None 15834052 Common - putative permease ECs4798 82 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15832953 Common - 2-deoxy-D-gluconate 3-dehydrogenase ECs3699 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15832966 Common - hypothetical protein ECs3712 178 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 162139755 Common garR tartronate semialdehyde reductase ECs4003 178 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 15831299 Common - putative ATP-binding component of a transport system ECs2045 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15832442 Common - putative sugar nucleotide epimerase ECs3188 128 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 15833642 Common - putative Mg(2+) transport ATPase ECs4388 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 15834122 Common - cystathionine gamma-synthase ECs4868 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15829278 Common - putative fimbrial protein ECs0024 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15833477 Common - predicted isomerase ECs4223 47 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 15833689 Common - hypothetical protein ECs4435 47 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 15831625 Common - riboflavin synthase subunit alpha ECs2371 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 15830285 Common - hypothetical protein ECs1031 65 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 15832376 Common - putative transcriptional regulator ECs3122 187 COG0583 LysR, Transcriptional regulator Transcription 15829918 Common - putative amidase ECs0664 188 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15830162 Common - glutathione transporter ATP-binding protein ECs0908 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 15829707 Common - maltodextrin glucosidase ECs0453 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 15833194 Common uppP undecaprenyl pyrophosphate phosphatase ECs3940 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 15834217 Pathogen - hypothetical protein ECs4963 1 None None None 15830251 Common - lipid transporter ATP-binding/permease protein ECs0997 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15830032 Common - quinolinate synthetase ECs0778 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 15831405 Common - putative oxidoreductase ECs2151 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15832333 Common - hypothetical protein ECs3079 21 COG3082 COG3082, Uncharacterized protein conserved in bacteria Function unknown 15831357 Common - putative sulfatase ECs2103 91 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 15832483 Common - lipoprotein precursor ECs3229 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 15830276 Common - putative chaperone ECs1022 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15829271 Common nhaA pH-dependent sodium/proton antiporter ECs0017 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 15831915 Common fliA flagellar biosynthesis sigma factor ECs2661 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15830860 Common - putative phosphohydrolase ECs1606 66 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15832513 Common - aminotransferase ECs3259 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15831494 Common - putative tail length tape measure protein ECs2240 46 COG5281 COG5281, Phage-related minor tail protein Function unknown 15829368 Common - N-acetyl-anhydromuranmyl-L-alanine amidase ECs0114 109 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 15832622 Common - hypothetical protein ECs3368 4 None None None 15832850 Common - predicted outer membrane lipoprotein ECs3596 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15833892 Common rpmH 50S ribosomal protein L34 ECs4638 109 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 15832665 Common - hypothetical protein ECs3411 170 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15834511 Common - hypothetical protein ECs5257 13 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15834156 Pathogen - hypothetical protein ECs4902 3 None None None 15832552 Common - hypothetical protein ECs3298 119 COG1737 RpiR, Transcriptional regulators Transcription 15830048 Common - predicted hydrolase ECs0794 107 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15830801 Common - hypothetical protein ECs1547 6 None None None 15834400 Common mutL DNA mismatch repair protein ECs5146 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 15832418 Common - NADH dehydrogenase subunit J ECs3164 90 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 15830219 Common - macrolide transporter ATP-binding /permease protein ECs0965 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15830470 Common - putative lipoprotein Rz1 precursor ECs1216 1 None None None 15833166 Common - putative transcriptional regulator ECs3912 58 COG1737 RpiR, Transcriptional regulators Transcription 15830214 Common - putative surface protein ECs0960 49 COG2431 COG2431, Predicted membrane protein Function unknown 15831103 Common - aconitate hydratase ECs1849 222 COG1048 AcnA, Aconitase A Energy production and conversion 38704126 Common - predicted ligase ECs3782 190 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 15830993 Common - global DNA-binding transcriptional dual regulator H-NS ECs1739 26 COG2916 Hns, DNA-binding protein H-NS General function prediction only 38704096 Common - hypothetical protein ECs5497 1 None None None 15831456 Pathogen - hypothetical protein ECs2202 1 None None None 15832043 Common - hypothetical protein ECs2789 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834250 Pathogen - hypothetical protein ECs4996 1 None None None 15830626 Common - transposase ECs1372 17 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 15829740 Common - cytochrome o ubiquinol oxidase subunit II ECs0486 138 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 162139797 Common - YciI-like protein ECs1751 76 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 15831785 Common - hypothetical protein ECs2531 67 COG1971 COG1971, Predicted membrane protein Function unknown 15832525 Common - manganese transport protein MntH ECs3271 110 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 15834225 Common - hypothetical protein ECs4971 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 38704027 Common - copper homeostasis protein CutC ECs2584 59 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 15833055 Common - hypothetical lipoprotein ECs3801 17 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15832313 Common - fructose-specific PTS system IIBC component ECs3059 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 15831198 Common - hypothetical protein ECs1944 9 None None None 15830249 Common ihfB integration host factor subunit beta ECs0995 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15834275 Common - hypothetical protein ECs5021 8 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15830922 Common minE cell division topological specificity factor MinE ECs1668 80 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 15832568 Common - EutH ECs3314 18 COG3192 EutH, Ethanolamine utilization protein Amino acid transport and metabolism 15831504 Common - putative major head protein/prohead protease ECs2250 23 COG3740 COG3740, Phage head maturation protease General function prediction only 15832473 Common - putative fimbrial protein ECs3219 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15829876 Common - phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex ECs0622 25 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 15833672 Common - hypothetical protein ECs4418 18 None None None 15829342 Common ftsI FtsI ECs0088 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15829888 Common - 2,3-dihydro-2,3-dihydroxybenzoate synthetase ECs0634 87 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 15832415 Common - NADH dehydrogenase subunit M ECs3161 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 15829862 Common - sensor kinase CusS ECs0608 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15833176 Common nudF ADP-ribose pyrophosphatase NudF ECs3922 106 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 15829936 Common - hypothetical protein ECs0682 110 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15829516 Common - hypothetical protein ECs0262 13 COG1690 RtcB, Uncharacterized conserved protein Function unknown 15829687 Common - bacterial alkaline phosphatase ECs0433 84 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 15830338 Common - putative anti-termination protein ECs1084 6 None None None 15830390 Common - phosphoanhydride phosphorylase ECs1136 17 None None None 15831804 Common - putative resistance protein ECs2550 44 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 15829950 Common - putative transport protein ECs0696 220 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 15831240 Common - putative tail assembly protein ECs1986 14 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15834465 Common - hypothetical protein ECs5211 61 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 15832160 Common - phosphomethylpyrimidine kinase ECs2906 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 15832272 Common - putative transport system permease protein ECs3018 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 15832899 Common rumA 23S rRNA 5-methyluridine methyltransferase ECs3645 201 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 15831815 Common - phosphogluconate dehydratase ECs2561 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15831461 Common - hypothetical protein ECs2207 5 None None None 15831989 Common - putative terminase large subunit ECs2735 36 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 15832636 Common - putative anaerobic dimethyl sulfoxide reductase chain C ECs3382 16 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 15833092 Common - hypothetical protein ECs3838 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 15834342 Common - phosphonate/organophosphate ester transporter subunit ECs5088 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 15831728 Common ansA cytoplasmic asparaginase I ECs2474 139 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 15829884 Common - enterobactin exporter EntS ECs0630 63 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15834233 Common - putative tail sheath protein ECs4979 21 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 15832359 Common - phosphotransfer intermediate protein in two-component regulatory system with RcsBC ECs3105 67 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15829327 Pathogen - hypothetical protein ECs0073 2 None None None 38703996 Common - hypothetical protein ECs5456 7 None None None 15832635 Common - putative polyferredoxin ECs3381 22 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15831950 Common - hypothetical protein ECs2696 61 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 15834600 Common serB phosphoserine phosphatase ECs5346 155 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15831327 Common - hypothetical protein ECs2073 19 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 38703976 Common - hypothetical protein ECs2031 24 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 15832668 Common - putative LACI-type transcriptional regulator ECs3414 87 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15832249 Pathogen - putative superinfection exclusion protein ECs2995 2 None None None 15830789 Pathogen - putative lipoprotein Rz1 precursor ECs1535 1 None None None 15831486 Common - putative outer membrane protein ECs2232 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15833042 Common - arginine/ornithine transport system ATPase ECs3788 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 15829790 Common - hypothetical protein ECs0536 72 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 15834509 Common - hypothetical protein ECs5255 6 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 15834259 Common - 23S rRNA pseudouridine synthase F ECs5005 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15831957 Common - hypothetical protein ECs2703 16 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15831320 Common - hypothetical protein ECs2066 45 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 15829797 Common - putative ATP-binding component of a transport system ECs0543 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 15834516 Common - hypothetical protein ECs5262 47 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 15832402 Common - O-succinylbenzoic acid--CoA ligase ECs3148 212 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15833849 Common - cytoplasmic membrane lipoprotein-28 ECs4595 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 15831022 Common - hypothetical protein ECs1768 11 COG5529 COG5529, Pyocin large subunit General function prediction only 15832456 Common truA tRNA pseudouridine synthase A ECs3202 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 15833087 Common ansB L-asparaginase II ECs3833 140 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 15831923 Common - hypothetical protein ECs2669 30 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15832038 Common - nitrogen assimilation transcriptional regulator ECs2784 189 COG0583 LysR, Transcriptional regulator Transcription 15830648 Pathogen - hypothetical protein ECs1394 1 None None None 15831314 Common - VgrE ECs2060 59 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 15830477 Common - hypothetical protein ECs1223 9 None None None 15834121 Common - transcriptional repressor protein MetJ ECs4867 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 15831910 Common - putative transport system permease protein ECs2656 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15832947 Common - bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase ECs3693 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15829541 Common - putative transcription regulator ECs0287 4 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15830127 Common - hypothetical protein ECs0873 144 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15830428 Common - exonuclease ECs1174 13 None None None 15832467 Common - chorismate synthase ECs3213 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 15829607 Common - hypothetical protein ECs0353 1 None None None 15830689 Common - putative cytochrome ECs1435 91 COG3038 CybB, Cytochrome B561 Energy production and conversion 15833080 Common - putative protein transport ECs3827 214 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 15830965 Common - putative sulfate transporter YchM ECs1711 156 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 15831600 Common - tyrosyl-tRNA synthetase ECs2346 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15829883 Common - iron-enterobactin transporter membrane protein ECs0629 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15832855 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ECs3601 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 162139731 Common - DNA-damage-inducible SOS response protein ECs5027 89 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15829397 Common - predicted outer membrane usher protein ECs0143 31 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15830491 Pathogen - hypothetical protein ECs1237 3 None None None 15833763 Common coaD phosphopantetheine adenylyltransferase ECs4509 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 15830058 Pathogen - hypothetical protein ECs0804 1 None None None 15830112 Common - putative structural protein ECs0858 95 COG0391 COG0391, Uncharacterized conserved protein Function unknown 38703991 Common - putative tail fiber protein ECs2159 4 None None None 15833343 Common - aerobic respiration control sensor protein ArcB ECs4089 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15830462 Common - putative transposase ECs1208 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831362 Common - putative fimbrial-like protein ECs2108 8 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15831707 Common - arginine succinyltransferase ECs2453 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 15832118 Common - predicted glycosyl transferase ECs2864 156 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15834035 Common - hypothetical protein ECs4781 18 COG3084 COG3084, Uncharacterized protein conserved in bacteria Function unknown 15833531 Common - glycogen branching enzyme ECs4277 149 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 15832760 Pathogen - hypothetical lipoprotein ECs3506 6 None None None 15830138 Common - hypothetical protein ECs0884 10 None None None 15832305 Common - endonuclease IV ECs3051 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 15830190 Common - putrescine transporter subunit: membrane component of ABC superfamily ECs0936 211 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 15831556 Common - putative transport protein ECs2302 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832352 Common - ecotin precursor ECs3098 23 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 15829653 Common - putative transcriptional regulator ECs0399 138 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15831346 Common - D-alanyl-D-alanine dipeptidase ECs2092 59 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 15833545 Pathogen - hypothetical protein ECs4291 3 None None None 15831695 Common - DNA-binding transcriptional dual regulator ECs2441 92 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15829685 Common ddl D-alanyl-alanine synthetase A ECs0431 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 15832506 Common - putative transporter YfdV ECs3252 58 COG0679 COG0679, Predicted permeases General function prediction only 15834367 Common - lysine decarboxylase 1 ECs5113 88 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 162139772 Common - NADH dehydrogenase subunit N ECs3160 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 15832458 Common - erythronate-4-phosphate dehydrogenase ECs3204 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15830902 Common - host specificity protein ECs1648 19 COG4733 COG4733, Phage-related protein, tail component Function unknown 15833868 Common emrD multidrug resistance protein D ECs4614 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15834131 Pathogen - hypothetical protein ECs4876 2 None None None 15834326 Common - putative carbohydrate ABC transport system permease ECs5072 111 COG4158 COG4158, Predicted ABC-type sugar transport system, permease component General function prediction only 15831943 Common fliR flagellar biosynthesis protein FliR ECs2689 119 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 15833976 Common - glucose-1-phosphate thymidylyltransferase ECs4722 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15830014 Common - hypothetical protein ECs0760 17 None None None 15830546 Common - putative ATP binding protein of ABC transporter ECs1292 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15829453 Common metQ DL-methionine transporter substrate-binding subunit ECs0199 101 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 15832718 Common - phospho-2-dehydro-3-deoxyheptonate aldolase ECs3464 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 15833962 Common - ketol-acid reductoisomerase ECs4708 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 15832387 Common - putative transposase ECs3133 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833985 Common - arylsulfatase ECs4731 67 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 15829834 Common - membrane protein FdrA ECs0580 126 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 15831247 Pathogen - hypothetical protein ECs1993 1 None None None 15832747 Common - hypothetical protein ECs3493 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832939 Common - prolipoprotein diacylglyceryl transferase ECs3685 205 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 15829292 Common - CaiE ECs0038 195 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 15833811 Common - SepL ECs4557 5 None None None 15830417 Pathogen - hypothetical protein ECs1163 2 None None None 15832740 Pathogen - hypothetical protein ECs3486 2 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 15834333 Common - ATP-binding component of phosphonate transport ECs5079 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 15833918 Common - phosphate transporter subunit ECs4664 138 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 15834092 Common - DNA-binding response regulator in two-component regulatory system with CpxA ECs4838 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15830150 Common - hypothetical protein ECs0896 87 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 38704252 Common - putative oxidoreductase ECs5241 189 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 162139745 Common nepI ribonucleoside transporter ECs4596 169 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830081 Common - putative portal protein ECs0827 35 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 15830654 Pathogen - hypothetical protein ECs1400 1 None None None 38703966 Common - hypothetical protein ECs1930 4 None None None 15831652 Common - putative amino acid/amine transport protein ECs2398 21 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832575 Common - hypothetical protein ECs3321 11 COG4812 EutT, Ethanolamine utilization cobalamin adenosyltransferase Amino acid transport and metabolism 15832098 Pathogen - O antigen polymerase ECs2844 1 None None None 15832068 Common - hypothetical protein ECs2814 18 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15834032 Common hemG protoporphyrinogen oxidase ECs4778 37 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 15830611 Pathogen - hypothetical protein ECs1357 1 None None None 15829772 Common - potassium efflux protein KefA ECs0518 228 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15832423 Common - NADH dehydrogenase subunit E ECs3169 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 38704095 Common upp uracil phosphoribosyltransferase ECs3360 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 15832164 Pathogen - putative outer membrane protein ECs2910 2 None None None 15832268 Common - putative transcriptional regulator ECs3014 13 COG0789 SoxR, Predicted transcriptional regulators Transcription 15832537 Common ligA NAD-dependent DNA ligase LigA ECs3283 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15831868 Common - hypothetical protein ECs2614 13 None None None 15833132 Common - predicted maturation element for hydrogenase 2 ECs3878 79 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 15832261 Common - hypothetical protein ECs3007 4 None None None 15831225 Common - putative terminase large subunit ECs1971 35 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 15831394 Common - O-acetylserine/cysteine export protein ECs2140 175 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 15832131 Common - 3-methyl-adenine DNA glycosylase II ECs2877 104 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 38704214 Common - hypothetical protein ECs4872 139 COG2962 RarD, Predicted permeases General function prediction only 15831121 Common - putative ATP-binding protein of peptide transport system ECs1867 249 COG4167 SapF, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15834430 Common rpsF 30S ribosomal protein S6 ECs5176 188 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 15833793 Common - hypothetical protein ECs4539 8 None None None 15832488 Pathogen - hypothetical protein ECs3234 1 None None None 15833505 Common feoB ferrous iron transport protein B ECs4251 180 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 15831616 Common - putative ATP-dependent helicase Lhr ECs2362 163 COG1201 Lhr, Lhr-like helicases General function prediction only 15832051 Common - hypothetical protein ECs2797 5 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 15831694 Common - phospho-beta-glucosidase ECs2440 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 15831108 Common - orotidine 5'-phosphate decarboxylase ECs1854 170 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 15831091 Pathogen - trp operon leader peptide ECs1837 1 None None None 15831457 Pathogen - hypothetical protein ECs2203 2 COG1710 COG1710, Uncharacterized protein conserved in archaea Function unknown 38704010 Common - hypothetical protein ECs2436 2 None None None 15834354 Common - DNA-binding transcriptional dual regulator ECs5100 112 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15832900 Common - hybrid sensory histidine kinase BarA ECs3646 226 COG4999 COG4999, Uncharacterized domain of BarA-like signal transduction histidine kinases Signal transduction mechanisms 15832263 Common - hypothetical protein ECs3009 2 None None None 15831670 Common - vitamin B12-transporter ATPase ECs2416 249 COG4138 BtuD, ABC-type cobalamin transport system, ATPase component Coenzyme metabolism 38704235 Common - entericidin B membrane lipoprotein ECs5586 9 COG5510 COG5510, Predicted small secreted protein Function unknown 15834206 Common - putative host-nuclease inhibitor protein ECs4952 9 COG4396 COG4396, Mu-like prophage host-nuclease inhibitor protein Gam General function prediction only 15832240 Common - phage replication protein P ECs2986 11 None None None 15833694 Common - putative transcriptional regulator ECs4440 9 COG2944 COG2944, Predicted transcriptional regulator Transcription 38704184 Common - RfaP ECs4505 10 None None None 15829978 Common - potassium-transporting ATPase subunit C ECs0724 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 15830513 Common - putative tet operon regulator ECs1259 64 COG1309 AcrR, Transcriptional regulator Transcription 38704191 Pathogen - hypothetical protein ECs5539 1 None None None 15831330 Common - putaive outer membrane porin protein ECs2076 31 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15831547 Common - putative oxidoreductase major subunit ECs2293 185 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15831439 Common - putative antirepressor protein ECs2185 8 None None None 15829476 Common - hypothetical protein ECs0222 11 None None None 15830731 Common - DNA polymerase III subunit delta' ECs1477 185 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 15832868 Common - hypothetical protein ECs3614 18 None None None 15833116 Common - putative transposase ECs3862 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833125 Common - hypothetical protein ECs3871 47 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833920 Common - putative fimbrial protein ECs4666 7 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15830720 Common - hypothetical protein ECs1466 55 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 15833021 Common - flavodoxin FldB ECs3767 67 COG0716 FldA, Flavodoxins Energy production and conversion 15832696 Common - ATP-dependent RNA helicase SrmB ECs3442 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15834111 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase ECs4857 104 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 38704119 Common xni exonuclease IX ECs3658 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 38703965 Common - putative aminohydrolase ECs1922 161 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 15829891 Common - carbon starvation protein ECs0637 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 15829332 Common - 2-isopropylmalate synthase ECs0078 216 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15831262 Common - putative dehydrogenase ECs2008 163 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 15829758 Common - nitrogen regulatory protein P-II 2 ECs0504 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15833596 Common - holo-(acyl carrier protein) synthase 2 ECs4342 45 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 15833731 Common mtlR mannitol repressor protein ECs4477 18 COG3722 MtlR, Transcriptional regulator Transcription 162139813 Common fadE acyl-CoA dehydrogenase ECs0248 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 15831429 Pathogen - putative head decoration protein ECs2175 4 None None None 15830505 Common - putative anti-repressor protein ECs1251 20 COG3561 COG3561, Phage anti-repressor protein Transcription 15829578 Common - putative regulator ECs0324 4 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 15834200 Common - putative DNA transposition protein ECs4946 18 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 15829387 Common - putative PTS enzyme II B component ECs0133 39 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 15831747 Common - hypothetical protein ECs2493 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 38704164 Common - hypothetical protein ECs4234 6 None None None 15829446 Common - hypothetical protein ECs0192 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 15831540 Common - hypothetical protein ECs2286 10 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15829458 Common - putative transcriptional regulator ECs0204 192 COG0583 LysR, Transcriptional regulator Transcription 15832002 Pathogen - hypothetical protein ECs2748 1 None None None 15830941 Common ldcA L,D-carboxypeptidase A ECs1688 81 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 15831177 Common - putative DNA-binding transcriptional regulator ECs1923 193 COG0583 LysR, Transcriptional regulator Transcription 15834500 Common - hypothetical protein ECs5246 4 None None None 15831278 Common - hypothetical protein ECs2024 5 None None None 15832932 Common - protease III ECs3678 183 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 15832501 Common - multidrug resistance protein K ECs3247 142 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15834597 Common deoD purine nucleoside phosphorylase ECs5343 95 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 15829486 Common - hypothetical protein ECs0232 2 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 15830244 Common - phosphoserine aminotransferase ECs0990 110 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 15831770 Common - hypothetical protein ECs2516 165 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 15833307 Common - putative alkaline phosphatase I ECs4053 62 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15831284 Pathogen - hypothetical protein ECs2030 2 None None None 15830421 Pathogen - hypothetical protein ECs1167 1 None None None 38704055 Pathogen - hypothetical protein ECs5481 2 None None None 15833111 Pathogen - hypothetical protein ECs3857 2 None None None 15830695 Common - predicted lipoprotein ECs1441 19 None None None 15831855 Common - transcriptional activator FlhC ECs2601 27 None None None 15833861 Pathogen - hypothetical protein ECs4607 1 None None None 15832434 Common - acetate kinase ECs3180 162 COG0282 ackA, Acetate kinase Energy production and conversion 15832108 Common - mannose-1-phosphate guanyltransferase ECs2854 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 15830893 Pathogen - minor tail protein ECs1639 4 None None None 15832542 Common - phosphoenolpyruvate-protein phosphotransferase ECs3288 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 15832280 Common - tRNA-dihydrouridine synthase C ECs3026 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15832621 Common - putative outer membrane lipoprotein ECs3367 4 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 15834118 Common - RhsH ECs4864 67 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15833466 Common - cell filamentation protein Fic ECs4212 37 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 15833523 Common glpD glycerol-3-phosphate dehydrogenase ECs4269 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15830977 Common - cation transport regulator ECs1723 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 15833807 Common - hypothetical protein ECs4553 2 None None None 15833551 Common - glycerol-3-phosphate transporter membrane protein ECs4297 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 15832075 Common hisD histidinol dehydrogenase ECs2821 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 15833159 Common - hypothetical protein ECs3905 31 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 15830200 Common - arginine 3rd transport system periplasmic binding protein ECs0946 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 38703857 Common - hypothetical protein ECs5377 34 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 15829605 Common - hypothetical protein ECs0351 2 None None None 15834485 Common - ornithine carbamoyltransferase subunit I ECs5231 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 15830207 Common - putative regulator ECs0953 106 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 15834083 Common - rhamnulose-1-phosphate aldolase ECs4829 21 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 15829994 Common - putative transport protein ECs0740 54 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 15833512 Common malQ 4-alpha-glucanotransferase ECs4258 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 15834186 Common - malate synthase ECs4932 83 COG2225 AceB, Malate synthase Energy production and conversion 15831246 Common - putative tail fiber protein ECs1992 23 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 38703905 Common - hypothetical protein ECs1030 17 None None None 15833243 Common - hypothetical protein ECs3989 4 None None None 15830098 Common - putative tail fiber protein ECs0844 30 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15834528 Common - FimI ECs5274 20 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832601 Common hyfE hydrogenase 4 membrane subunit ECs3347 34 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 15830918 Common - hypothetical protein ECs1664 74 COG1396 HipB, Predicted transcriptional regulators Transcription 15831375 Common - putative transport system permease protein ECs2121 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 15833331 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase ECs4077 106 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 15830089 Pathogen - putative minor tail protein ECs0835 3 None None None 15834531 Common - FimF ECs5277 21 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15834470 Common - trehalose-6-phosphate hydrolase ECs5216 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 15833824 Pathogen - hypothetical protein ECs4570 1 None None None 15833854 Common - hypothetical protein ECs4600 134 COG2252 COG2252, Permeases General function prediction only 15829284 Common lspA lipoprotein signal peptidase ECs0030 195 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 38704071 Common - NADH dehydrogenase subunit G ECs3167 188 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 38704063 Common napB diheme cytochrome c550 ECs3092 40 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 15830186 Common - ribosomal protein S6 modification protein ECs0932 153 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 15831186 Common lar restriction alleviation and modification protein ECs1932 2 None None None 15832357 Common - thiamine biosynthesis lipoprotein ApbE ECs3103 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 38703875 Common - putative purine permease YbbY ECs0575 69 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15829425 Common rpsB 30S ribosomal protein S2 ECs0171 226 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 15829674 Common tauB taurine transporter ATP-binding subunit ECs0420 249 COG4525 TauB, ABC-type taurine transport system, ATPase component Inorganic ion transport and metabolism 15831148 Common - putative dehydrogenase ECs1894 189 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15829258 Common - threonine synthase ECs0004 163 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 15829975 Common - ornithine decarboxylase isozyme ECs0721 82 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 15831904 Common - phosphatidylglycerophosphate synthetase ECs2650 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15832994 Common - xanthine dehydrogenase subunit XdhB ECs3740 103 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 15830091 Common - putative tail length tape measure protein precursor ECs0837 63 COG5281 COG5281, Phage-related minor tail protein Function unknown 15833890 Common - DNA polymerase III subunit beta ECs4636 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 15833578 Common - hypothetical lipoprotein ECs4324 13 None None None 15831337 Common - NAD-linked malate dehydrogenase ECs2083 200 COG0281 SfcA, Malic enzyme Energy production and conversion 15833659 Common - EAL domain containing protein involved in flagellar function ECs4405 127 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15833818 Pathogen - hypothetical protein ECs4564 1 None None None 15833118 Pathogen - hypothetical protein ECs3864 1 None None None 15833527 Common - glycogen phosphorylase ECs4273 146 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 15829491 Common - RhsG core protein with extension ECs0237 71 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15831993 Common - putative lipoprotein precursor ECs2738 2 None None None 15834344 Common - hypothetical protein ECs5090 107 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 15832189 Common - hypothetical protein ECs2935 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 38703987 Common - hypothetical protein ECs2102 118 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 15830891 Pathogen - minor capsid protein ECs1637 3 None None None 15831745 Common - putative scaffolding protein in the formation of a murein-synthesizing holoenzyme ECs2491 33 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 38704144 Common - ATP-dependent RNA helicase DeaD ECs4043 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15833410 Common mscL large-conductance mechanosensitive channel ECs4156 143 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15830878 Common - lipoprotein Rz1 precursor ECs1624 1 None None None 15832982 Pathogen - hypothetical protein ECs3728 1 None None None 38704259 Common - hypothetical protein ECs5289 19 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 38704057 Common - multidrug resistance outer membrane protein MdtQ ECs3025 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15833416 Common - 30S ribosomal protein S11 ECs4162 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 15833660 Common - ketodeoxygluconokinase ECs4406 146 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15834425 Common - L-ascorbate-specific enzyme IIA component of PTS ECs5171 46 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 38704134 Pathogen - hypothetical protein ECs5518 1 None None None 15834109 Pathogen - hypothetical protein ECs4855 2 None None None 15833443 Common - bacterioferritin, iron storage and detoxification protein ECs4189 106 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 15833368 Common - p-hydroxybenzoic acid efflux subunit AaeA ECs4114 147 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15834007 Common - threonine efflux system ECs4753 105 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 15829791 Common - copper transporter ECs0537 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15832915 Common - L-fucose transporter ECs3661 47 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 15830306 Common - hypothetical protein ECs1052 136 COG1254 AcyP, Acylphosphatases Energy production and conversion 15832645 Common - [2FE-2S] ferredoxin ECs3391 104 COG0633 Fdx, Ferredoxin Energy production and conversion 15830608 Common - TerC ECs1354 97 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15830104 Pathogen - hypothetical protein ECs0850 3 None None None 15832908 Common queF 7-cyano-7-deazaguanine reductase ECs3654 86 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 15832146 Common - lipid kinase ECs2892 107 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 15833571 Common - hypothetical protein ECs4317 15 COG3714 COG3714, Predicted membrane protein Function unknown 15829434 Common - periplasmic chaperone ECs0180 55 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 15831040 Common - endopeptidase ECs1786 9 None None None 15830075 Pathogen - putative lipoprotein Rz1 precursor ECs0821 2 None None None 15832141 Common - DNA-binding response regulator in two-component regulatory system with BaeS ECs2887 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15829294 Common caiC putative crotonobetaine/carnitine-CoA ligase ECs0040 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15830976 Common chaB cation transport regulator ECs1722 22 COG4572 ChaB, Putative cation transport regulator General function prediction only 15834050 Common - putative resistance protein ECs4796 58 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15833881 Common - heat shock protein IbpA ECs4627 67 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 15833316 Common obgE GTPase ObgE ECs4062 228 COG0536 Obg, Predicted GTPase General function prediction only 15833773 Common - hypothetical protein ECs4519 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 15830747 Common - hypothetical protein ECs1493 16 COG4763 COG4763, Predicted membrane protein Function unknown 15832848 Common - transcriptional regulator (MarR-family) ECs3594 100 COG1846 MarR, Transcriptional regulators Transcription 15831051 Common - putative head-tail adaptor ECs1797 3 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 15831719 Common - pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase ECs2465 162 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15832973 Common - EprH ECs3719 6 None None None 15834124 Common metF 5,10-methylenetetrahydrofolate reductase ECs4870 151 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 15831146 Common - putative oxidoreductase ECs1892 124 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 38704201 Common - hypothetical protein ECs4697 126 COG2186 FadR, Transcriptional regulators Transcription 15829626 Common - putative carbamate kinase ECs0372 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 15830742 Common - hypothetical protein ECs1488 48 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 15833704 Common - putative ATP-binding protein of xylose transport system ECs4450 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15831235 Common - putative tail assembly chaperon ECs1981 4 None None None 15833232 Common - hypothetical protein ECs3978 9 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15830786 Common - putative endolysin ECs1532 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15834388 Common - fumarate reductase iron-sulfur subunit ECs5134 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 15834585 Common rimI ribosomal-protein-alanine N-acetyltransferase ECs5331 204 COG0456 RimI, Acetyltransferases General function prediction only 15829479 Common - hypothetical protein ECs0225 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 15829513 Common - putative antitoxin of the YafO-YafN toxin-antitoxin system ECs0259 11 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 15829538 Common - DNA-invertase ECs0284 138 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15830911 Common - hypothetical protein ECs1657 8 None None None 15833242 Common - hypothetical protein ECs3988 97 COG1741 COG1741, Pirin-related protein General function prediction only 15833057 Common - putative ABC-transporter ATP-binding subunit ECs3803 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 15829378 Common - S-adenosylmethionine decarboxylase ECs0124 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 15834000 Common - magnesium/nickel/cobalt transporter CorA ECs4746 148 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 15831388 Common - hypothetical protein ECs2134 2 None None None 15830399 Common - DNA-binding transcriptional regulator ECs1145 179 COG1278 CspC, Cold shock proteins Transcription 38704194 Pathogen - hypothetical protein ECs5541 3 None None None 15830595 Common - hypothetical protein ECs1341 51 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 38703848 Pathogen - hypothetical protein ECs5364 1 None None None 15829589 Common - putative oxidoreductase ECs0335 186 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 15829508 Common - putative lipoprotein ECs0254 127 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15833286 Common - hypothetical protein ECs4032 70 COG0701 COG0701, Predicted permeases General function prediction only 15831663 Common - phosphoenolpyruvate synthase ECs2409 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15834497 Common - putative transposase ECs5243 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829814 Common - RhsD ECs0560 69 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15833225 Common - putative transport protein ECs3971 106 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 15831623 Common - inner membrane transport protein YdhC ECs2369 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15833213 Common ebgC cryptic beta-D-galactosidase subunit beta ECs3959 8 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 15834365 Common lysS lysyl-tRNA synthetase ECs5111 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15829262 Common - transaldolase B ECs0008 185 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15832998 Common - diaminopropionate ammonia-lyase ECs3744 92 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 15833454 Common - FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) ECs4200 125 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 15832727 Common - signal recognition particle protein ECs3473 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 15832968 Common - hypothetical protein ECs3714 1 None None None 15833210 Common - hypothetical protein ECs3956 167 COG0073 ARC1, EMAP domain General function prediction only 15833274 Common - putative fimbrial-like protein ECs4020 12 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 38704155 Common - putative methyltransferase ECs4134 145 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15831111 Common - putative DEOR-type transcriptional regulator ECs1857 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15833347 Common - hypothetical protein ECs4093 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 15830133 Common - putative dehydrogenase ECs0879 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 38704009 Common - hypothetical protein ECs2434 36 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 15829580 Common - hypothetical protein ECs0326 1 None None None 15829760 Common - acyl-CoA thioesterase II ECs0506 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 15832211 Common - hypothetical protein ECs2957 21 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 15832252 Pathogen - Kil protein ECs2998 2 None None None 15831130 Common - DNA-binding transcriptional repressor ECs1876 105 COG1396 HipB, Predicted transcriptional regulators Transcription 15829946 Common - glutamate/aspartate transport system permease ECs0692 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15831975 Common - putative tail assembly protein ECs2721 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 15829702 Common - exonuclease subunit SbcD ECs0448 112 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 15829371 Common pdhR transcriptional regulator PdhR ECs0117 150 COG2186 FadR, Transcriptional regulators Transcription 15831721 Common - glutamate dehydrogenase ECs2467 174 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 15834078 Common - frv operon protein ECs4824 90 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 15830709 Common flgF flagellar basal body rod protein FlgF ECs1455 121 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 15833711 Common - putative transcriptional regulator ECs4457 105 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 15832826 Common - cryptic 6-phospho-beta-glucosidase ECs3572 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15833269 Common - N-acetylgalactosamine-6-phosphate deacetylase ECs4015 119 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 15833736 Common - DNA-binding transcriptional repressor ECs4482 133 COG2186 FadR, Transcriptional regulators Transcription 15831988 Pathogen - putative head completion protein ECs2734 2 None None None 162139788 Common - transcriptional regulator SlyA ECs2351 119 COG1846 MarR, Transcriptional regulators Transcription 15829937 Common - hypothetical protein ECs0683 5 None None None 15831154 Common - hypothetical protein ECs1900 42 COG3106 COG3106, Predicted ATPase General function prediction only 15833930 Common - F0F1 ATP synthase subunit alpha ECs4676 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 15833729 Common - mannitol-specific PTS system enzyme IIABC components ECs4475 71 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 15833322 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase ECs4068 219 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 15833399 Common - putative transferase ECs4145 190 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 15833830 Common - CesD ECs4576 17 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15831742 Common - glyceraldehyde-3-phosphate dehydrogenase ECs2488 222 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15833262 Common - hypothetical protein ECs4008 21 None None None 15830832 Pathogen - hypothetical protein ECs1578 1 None None None 15831274 Common - hypothetical protein ECs2020 11 COG1434 COG1434, Uncharacterized conserved protein Function unknown 15833146 Common - cystathionine beta-lyase ECs3892 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15829349 Common murC UDP-N-acetylmuramate--L-alanine ligase ECs0095 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 162139818 Common - SecA regulator SecM ECs0101 11 None None None 15831765 Common - hypothetical protein ECs2511 89 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 15831880 Pathogen - hypothetical protein ECs2626 1 None None None 15833721 Common - selenocysteinyl-tRNA-specific translation factor ECs4467 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 15832017 Common - hypothetical protein ECs2763 10 COG5529 COG5529, Pyocin large subunit General function prediction only 15833937 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA ECs4683 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15830432 Pathogen - regulatory protein cIII ECs1178 2 None None None 15831827 Common ruvC Holliday junction resolvase ECs2573 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 38704077 Common - hypothetical protein ECs3226 15 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 15832444 Common - histidine/lysine/arginine/ornithine transporter subunit ECs3190 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 15829865 Common - periplasmic copper-binding protein ECs0611 24 COG5569 COG5569, Uncharacterized conserved protein Function unknown 15832590 Common - hypothetical protein ECs3336 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 15830121 Common - cardiolipin synthase 2 ECs0867 142 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15830038 Common galM aldose 1-epimerase ECs0784 95 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 15831876 Common - putative DNA-binding protein ECs2622 7 None None None 15830460 Pathogen - Shiga toxin 2 subunit B ECs1206 2 None None None 15831841 Common - hypothetical protein ECs2587 3 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 15831097 Common - short chain dehydrogenase ECs1843 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15831561 Common tqsA putative transport protein ECs2307 186 COG0628 PerM, Predicted permease General function prediction only 15831004 Common - voltage-gated potassium channel ECs1750 109 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15832751 Common - holin protein ECs3497 5 None None None 15832586 Common - aminoglycoside/multidrug efflux system ECs3332 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 15832999 Common - peptidase ECs3745 196 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 38703928 Common - hypothetical protein ECs1413 16 None None None 15830502 Pathogen - hypothetical protein ECs1248 1 None None None 15830261 Common mukB cell division protein MukB ECs1007 30 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 15832053 Pathogen - hypothetical protein ECs2799 2 None None None 15830493 Pathogen - hypothetical protein ECs1239 3 None None None 15833991 Common cyaY frataxin-like protein ECs4738 44 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 15834595 Common deoA thymidine phosphorylase ECs5341 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 15831282 Common - hypothetical protein ECs2028 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 15832447 Common - histidine transport system histidine-binding periplasmic protein ECs3193 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15833183 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase ECs3929 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 15834014 Common - hypothetical protein ECs4760 116 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 15831712 Common - hypothetical protein ECs2458 112 COG0398 COG0398, Uncharacterized conserved protein Function unknown 162139765 Common - stationary phase inducible protein CsiE ECs3401 11 COG3711 BglG, Transcriptional antiterminator Transcription 15832478 Common fadJ multifunctional fatty acid oxidation complex subunit alpha ECs3224 172 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 15833102 Common - hypothetical protein ECs3848 58 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831032 Common - hypothetical protein ECs1778 4 None None None 15832174 Common metG methionyl-tRNA synthetase ECs2920 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15831376 Common - putative transport system permease protein ECs2122 102 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 15833205 Common - G/U mismatch-specific DNA glycosylase ECs3951 29 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 15833969 Common - putative rho operon leader peptide ECs4715 2 None None None 15832230 Common - hypothetical protein ECs2976 3 None None None 15829786 Common - fosmidomycin resistance protein ECs0532 66 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 15834102 Common - universal stress protein UspD ECs4848 24 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15829325 Common thiP thiamin transporter membrane protein ECs0071 179 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 15834329 Common phnP carbon-phosphorus lyase complex accessory protein ECs5075 61 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 15829981 Pathogen - KdpF protein of high-affinity potassium transport system ECs0727 1 None None None 15831676 Pathogen - phenylalanyl-tRNA synthetase operon leader peptide ECs2422 1 None None None 15834588 Common - periplasmic protein ECs5334 83 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 162139714 Common - autoinducer-2 (AI-2) kinase ECs2118 175 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 38704087 Common - EutG ECs3315 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 15829752 Common - queuosine biosynthesis protein QueC ECs0498 175 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 15832206 Common - hypothetical protein ECs2952 5 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15834481 Pathogen - hypothetical protein ECs5227 2 None None None 15833253 Common - DNA-binding transcriptional activator TdcR ECs3999 2 None None None 15829737 Common - cytochrome o ubiquinol oxidase subunit IV ECs0483 61 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 15833740 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase ECs4486 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15833900 Common - tryptophan permease TnaB ECs4646 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15830869 Common - hypothetical protein ECs1615 40 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 38703882 Pathogen - hypothetical protein ECs5383 1 None None None 15831380 Common - trans-aconitate 2-methyltransferase ECs2126 85 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 15829987 Common - deoxyribodipyrimidine photolyase ECs0733 133 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 15833325 Common - hypothetical protein ECs4071 78 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 38704186 Common slmA nucleoid occlusion protein ECs4516 54 COG1309 AcrR, Transcriptional regulator Transcription 162139757 Common - putrescine--2-oxoglutarate aminotransferase ECs3955 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 15834176 Common - hypothetical protein ECs4922 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 15833062 Common - mannitol-specific PTS system enzyme II component ECs3808 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 15833489 Common - hypothetical protein ECs4235 6 None None None 15829353 Common - cell division protein FtsZ ECs0099 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 15830363 Pathogen - putative head decoration protein ECs1109 3 None None None 15831345 Common - putative hemin-binding lipoprotein ECs2091 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15830636 Common - HecB-like protein ECs1382 21 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 15829721 Common ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ECs0467 230 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 15830173 Common - D-alanyl-D-alanine carboxypeptidase fraction C ECs0919 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15834571 Common - hypothetical protein ECs5317 51 COG1802 GntR, Transcriptional regulators Transcription 15830527 Common - FidL-like protein ECs1273 4 None None None 15830106 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase ECs0852 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 15833069 Common - hypothetical protein ECs3815 3 None None None 15831582 Common - DNA-binding transcriptional repressor ECs2328 122 COG1609 PurR, Transcriptional regulators Transcription 15829855 Common nfrB bacteriophage N4 adsorption protein B ECs0601 29 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15830326 Pathogen - hypothetical protein ECs1072 1 None None None 15832374 Common - hypothetical protein ECs3120 7 None None None 15832951 Common - putative racemase ECs3697 82 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 15833639 Common - ShuY-like protein ECs4385 36 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15830674 Common - cryptic curlin major subunit ECs1420 11 None None None 15833383 Common - hypothetical protein ECs4129 14 COG3924 COG3924, Predicted membrane protein Function unknown 15830226 Common - cysteine/glutathione ABC transporter membrane/ATP-binding component ECs0972 248 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 15831250 Pathogen - hypothetical protein ECs1996 2 None None None 15833131 Common - hydrogenase 2-specific chaperone ECs3877 21 None None None 15831681 Common - hypothetical protein ECs2427 4 None None None 15830403 Common - periplasmic sensory protein associated with the TorRS two-component regulatory system ECs1149 35 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15829498 Common - hypothetical protein ECs0244 1 None None None 15831295 Pathogen - hypothetical protein ECs2041 2 None None None 15834392 Common - predicted mechanosensitive channel ECs5138 184 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15834454 Common - hypothetical protein ECs5200 30 COG2105 COG2105, Uncharacterized conserved protein Function unknown 15832292 Common - putative oxidoreductase ECs3038 213 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 15833462 Common - cAMP-regulatory protein ECs4208 167 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15831750 Common - hypothetical protein ECs2496 16 COG2606 EbsC, Uncharacterized conserved protein Function unknown 15833138 Common - hypothetical protein ECs3884 120 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 15830563 Common - hypothetical protein ECs1309 11 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832344 Common - ATP binding protein of heme exporter A ECs3090 236 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 38704244 Common - putative transposase ECs5183 77 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830444 Common - replication protein P ECs1190 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15830532 Common - putative outer membrane usher protein ECs1278 36 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15831534 Common - hypothetical protein ECs2280 5 None None None 15833382 Common - acetyl-CoA carboxylase biotin carboxylase subunit ECs4128 232 COG0439 AccC, Biotin carboxylase Lipid metabolism 15830375 Common - putative host specificity protein ECs1121 18 COG4733 COG4733, Phage-related protein, tail component Function unknown 15829591 Common - putative transcription regulator ECs0337 106 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15831410 Pathogen - hypothetical protein ECs2156 2 None None None 162139763 Common - hypothetical protein ECs3480 68 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 15830516 Pathogen - hypothetical protein ECs1262 3 None None None 15833013 Common - putative oxidoreductase Fe-S binding subunit ECs3759 210 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 15833632 Common - hypothetical protein ECs4378 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15833341 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase ECs4087 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 15830268 Common - nicotinate phosphoribosyltransferase ECs1014 93 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 38703958 Common - putative amino acid/amine transport protein ECs1873 187 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15834436 Common - putative transposase ECs5182 76 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 162139820 Common - putative electron transfer flavoprotein FixA ECs0044 149 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 15834060 Common - putative kinase ECs4806 95 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15829641 Common prpD 2-methylcitrate dehydratase ECs0387 64 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 15832702 Common - thioredoxin 2 ECs3448 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15831848 Common - chemotaxis regulator, protein-glutamate methyltransferase ECs2594 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 15829843 Common - hypothetical protein ECs0589 11 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 15831736 Common - putative aldolase ECs2482 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15832012 Pathogen - hypothetical protein ECs2758 1 None None None 15830769 Pathogen - hypothetical protein ECs1515 2 None None None 15833192 Common - putative signal transduction protein ECs3938 32 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 15833374 Common maf Maf-like protein ECs4120 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 15833586 Common - putative (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase ECs4332 18 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 15834559 Common - hypothetical protein ECs5305 44 COG3586 COG3586, Uncharacterized conserved protein Function unknown 15833565 Common ftsX cell division protein FtsX ECs4311 112 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 38704208 Common - coproporphyrinogen III oxidase ECs4789 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15829598 Common - putative dehydrogenase subunit ECs0344 155 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 15829441 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha ECs0187 191 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 15831448 Common - putative crossover junction endodeoxyribonuclease ECs2194 7 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 15834223 Common - putative portal protein ECs4969 24 COG4373 COG4373, Mu-like prophage FluMu protein gp28 General function prediction only 15831966 Common - putative cytochrome ECs2712 86 COG3038 CybB, Cytochrome B561 Energy production and conversion 15834302 Common - hypothetical protein ECs5048 35 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 162139804 Common - hypothetical protein ECs0799 221 COG1048 AcnA, Aconitase A Energy production and conversion 15831170 Common - O-6-alkylguanine-DNA:cysteine-protein methyltransferase ECs1916 200 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 15831773 Common - hypothetical protein ECs2519 6 None None None 38704104 Common - putative NAGC-like transcriptional regulator ECs3416 134 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15830995 Common - CoA-linked acetaldehyde dehydrogenase ECs1741 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 15833403 Common - hypothetical protein ECs4149 90 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 15831955 Common - hypothetical protein ECs2701 3 None None None 15832672 Common - nitric oxide dioxygenase ECs3418 135 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 15829714 Common secF preprotein translocase subunit SecF ECs0460 220 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 15830315 Pathogen - hypothetical protein ECs1061 1 None None None 15830531 Common - putative outer membrane protein ECs1277 10 None None None 15834490 Common - DNA polymerase III subunit chi ECs5236 49 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 15834292 Common - hypothetical protein ECs5038 126 COG0432 COG0432, Uncharacterized conserved protein Function unknown 38703865 Common - hypothetical protein ECs0478 98 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15834299 Common - redox-sensing activator of soxS ECs5045 86 COG0789 SoxR, Predicted transcriptional regulators Transcription 15833756 Common - putative UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase ECs4502 31 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 15832713 Pathogen - hypothetical protein ECs3459 2 None None None 15832066 Common dacD D-alanyl-D-alanine carboxypeptidase ECs2812 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15830660 Common - hypothetical protein ECs1406 8 None None None 15833433 Common rpsC 30S ribosomal protein S3 ECs4179 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 15833482 Common - ribulose-phosphate 3-epimerase ECs4228 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 15832695 Common - hypothetical protein ECs3441 33 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 15831598 Common - glutathionine S-transferase ECs2344 84 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15831163 Common - hypothetical protein ECs1909 62 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 15831589 Common - hypothetical protein ECs2335 9 None None None 15832239 Pathogen - Ren protein ECs2985 1 None None None 38703879 Common - hypothetical protein ECs5381 26 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 15831513 Common - putative endolysin ECs2259 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15832157 Common - putative kinase ECs2903 55 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15832282 Common - putative glutathione-S-transferase ECs3028 86 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15829329 Common leuD isopropylmalate isomerase small subunit ECs0075 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 15833750 Common - hypothetical protein ECs4496 3 None None None 15831228 Common - putative portal protein ECs1974 63 COG4695 COG4695, Phage-related protein Function unknown 15831436 Pathogen - putative transcriptional regulator ECs2182 1 None None None 15832396 Common - undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase ECs3142 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15830987 Common - hypothetical protein ECs1733 1 None None None 38704051 Common - hypothetical protein ECs2913 9 COG5455 COG5455, Predicted integral membrane protein Function unknown 15833779 Common - bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase ECs4525 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 15831779 Common - putative transport protein ECs2525 214 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 38703950 Common - hypothetical protein ECs5423 2 None None None 15829879 Common entF enterobactin synthase subunit F ECs0625 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 15833662 Common - C4-dicarboxylate transporter DctA ECs4408 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 38703963 Common - hypothetical protein ECs1906 48 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15829680 Common - beta-lactamase/D-alanine carboxypeptidase ECs0426 109 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 38703894 Common - putative hydroxylase ECs0882 45 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 15831259 Common - hypothetical protein ECs2005 29 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 15832073 Pathogen - his operon leader peptide ECs2819 1 None None None 15831208 Common - hypothetical protein ECs1954 4 None None None 15829442 Common - lysine decarboxylase 2 ECs0188 88 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 15833007 Common - hypothetical protein ECs3753 19 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 15834518 Common - putative DNA helicase ECs5264 180 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15831393 Common - hypothetical protein ECs2139 4 None None None 15830518 Common - hypothetical protein ECs1264 27 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 162139743 Common - hypothetical protein ECs4628 11 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 15834099 Common - hypothetical protein ECs4845 11 None None None 15830197 Common - arginine 3rd transport system periplasmic binding protein ECs0943 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15829792 Common - glutaminase ECs0538 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 15832008 Common - prophage maintenance protein ECs2754 7 None None None 15830759 Common - hypothetical protein ECs1505 4 None None None 15834113 Common - ATP-dependent protease peptidase subunit ECs4859 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 15832979 Common spaP surface presentation of antigens protein SpaP ECs3725 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 15834452 Common - hypothetical protein ECs5198 129 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 15834252 Pathogen - putative DNA modification protein ECs4998 3 None None None 15830258 Common - putative metallothionein SmtA ECs1004 93 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 15831549 Common - putative oxidoreductase Fe-S subunit ECs2295 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15829745 Common clpP ATP-dependent Clp protease proteolytic subunit ECs0491 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15832504 Common - hypothetical protein ECs3250 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 38703968 Common - phage superinfection exclusion protein ECs1937 1 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 15829802 Common - adhesin/invasin-like protein ECs0548 16 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 15831967 Pathogen - hypothetical protein ECs2713 1 None None None 15832195 Common - putative tail fiber protein ECs2941 24 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15830489 Pathogen - hypothetical protein ECs1235 2 None None None 15832692 Common - anti-RNA polymerase sigma factor SigE ECs3438 32 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 15832102 Common - hypothetical protein ECs2848 5 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 38703858 Common - putative cytochrome subunit of dehydrogenase ECs0382 102 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 15829603 Common - hypothetical protein ECs0349 3 None None None 15832591 Common - hypothetical protein ECs3337 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 15832565 Common - ethanolamine ammonia-lyase small subunit ECs3311 54 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 15829799 Common - DNA-binding transcriptional activator of copper-responsive regulon genes ECs0545 145 COG0789 SoxR, Predicted transcriptional regulators Transcription 15829413 Common - chloride channel protein ECs0159 153 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 15832454 Common - acetyl-CoA carboxylase subunit beta ECs3200 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 15831554 Common - putative NAGC-like transcriptional regulator ECs2300 166 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15830616 Pathogen - hypothetical protein ECs1362 2 None None None 15832101 Common - putative UDP-galactose 4-epimerase ECs2847 228 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15830646 Pathogen - hypothetical protein ECs1392 1 None None None 15833123 Common - hypothetical protein ECs3869 61 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832802 Common - multidrug resistance membrane translocase ECs3548 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 38704238 Common - oligoribonuclease ECs5141 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 15833452 Common - FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) ECs4198 130 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 15830423 Common - hypothetical protein ECs1169 5 None None None 15830067 Common - serine/threonin protein phosphatase ECs0813 104 None None None 15832186 Common - putative transposase ECs2932 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833375 Common - rod shape-determining protein MreD ECs4121 50 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 15834045 Common glnL nitrogen regulation protein NR(II) ECs4791 219 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 15834557 Common - hypothetical protein ECs5303 4 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 15834506 Common - putative transcription regulator ECs5252 31 COG1396 HipB, Predicted transcriptional regulators Transcription 15829399 Common - putative fimbrial-like protein ECs0145 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15831303 Common - hypothetical protein ECs2049 8 None None None 15833200 Common - hypothetical protein ECs3946 73 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15830416 Pathogen - hypothetical protein ECs1162 1 None None None 15829701 Common - exonuclease subunit SbcC ECs0447 103 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 15833666 Common - cellulose synthase regulator protein ECs4412 20 None None None 15831122 Common - putative ATP-binding protein of peptide transport system ECs1868 249 COG4170 SapD, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15831442 Common - putative holin protein ECs2188 5 None None None 15831853 Common motB flagellar motor protein MotB ECs2599 114 COG1360 MotB, Flagellar motor protein Cell motility and secretion 15832203 Common - putative tail length tape measure protein precursor ECs2949 17 COG5281 COG5281, Phage-related minor tail protein Function unknown 15831168 Common - universal stress protein UspE ECs1914 52 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15831862 Common araG L-arabinose transporter ATP-binding protein ECs2608 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15832988 Common - EivF ECs3734 10 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15829547 Common - hypothetical protein ECs0293 7 None None None 15829390 Common - hypothetical protein ECs0136 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 15831110 Common - lipoprotein ECs1856 6 None None None 15832648 Common iscA iron-sulfur cluster assembly protein ECs3394 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 15831084 Common - putative structural proteins ECs1830 37 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 15833605 Common - putative phosphotransferase system enzyme IIB ECs4351 18 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 38704231 Common - multidrug efflux system protein MdtO ECs5063 14 COG1289 COG1289, Predicted membrane protein Function unknown 15829870 Common - dihydropteridine reductase ECs0616 62 COG0778 NfnB, Nitroreductase Energy production and conversion 15831056 Common - CHECK ME putative tail assembly chaperone ECs1802 3 None None None 15831850 Common - methyl-accepting chemotaxis protein II ECs2596 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15832494 Common - putative resolvase ECs3240 100 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15833358 Common rplM 50S ribosomal protein L13 ECs4104 240 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 15834064 Common - D-tyrosyl-tRNA deacylase ECs4810 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 15832707 Common - hypothetical protein ECs3453 11 COG5544 COG5544, Predicted periplasmic lipoprotein General function prediction only 15833987 Common - putative uroporphyrinogen III C-methyltransferase ECs4733 54 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 15833814 Pathogen - CesT ECs4560 2 None None None 15832811 Common - competence damage-inducible protein A ECs3557 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 15829823 Common - hydroxypyruvate isomerase ECs0569 83 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 15832742 Pathogen - hypothetical protein ECs3488 2 None None None 15831945 Common - hypothetical protein ECs2691 10 None None None 15832134 Common - hypothetical protein ECs2880 11 None None None 15831878 Pathogen - hypothetical protein ECs2624 1 None None None 38703959 Common - putative glutamine synthetase ECs1874 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 15831569 Common - sensor protein RstB ECs2315 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15833685 Common - putative fimbrial major protein precursor ECs4431 21 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15834310 Common - heme lyase subunit NrfE ECs5056 117 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 15833710 Common - hypothetical protein ECs4456 149 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15833688 Common - 3-methyl-adenine DNA glycosylase I ECs4434 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 15831693 Common - hypothetical protein ECs2439 58 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 15829692 Common aroL shikimate kinase II ECs0438 198 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 15829967 Common - hypothetical protein ECs0713 8 None None None 15834136 Common - PTS system fructose-like IIB component 2 ECs4882 68 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 15829484 Common - hypothetical protein ECs0230 9 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 15834594 Common - deoxyribose-phosphate aldolase ECs5340 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 15830655 Common - hypothetical protein ECs1401 23 None None None 15834076 Common - hypothetical protein ECs4822 8 None None None 15831917 Common fliD flagellar capping protein ECs2663 97 COG1345 FliD, Flagellar capping protein Cell motility and secretion 15834324 Common - hypothetical protein ECs5070 18 COG3822 COG3822, ABC-type sugar transport system, auxiliary component General function prediction only 15834463 Common - fructose-1,6-bisphosphatase ECs5209 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 15830968 Common lolB outer membrane lipoprotein LolB ECs1714 53 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 15834271 Common malE maltose ABC transporter periplasmic protein ECs5017 97 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 38704210 Common - superoxide dismutase ECs4834 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 15831808 Common - exodeoxyribonuclease X ECs2554 162 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15829959 Common - UMP phosphatase ECs0705 109 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 15831837 Common - putative cytochrome C-type protein ECs2583 53 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 15832717 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase ECs3463 89 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 15834044 Common glnG nitrogen regulation protein NR(I) ECs4790 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15830016 Common - putative glutamate mutase E ECs0762 17 COG4865 COG4865, Glutamate mutase epsilon subunit Amino acid transport and metabolism 15831709 Common - exonuclease III ECs2455 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15834185 Common - homoserine O-succinyltransferase ECs4931 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 15831006 Common - membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins ECs1752 31 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 15831096 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase ECs1842 130 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 15831119 Common - putative outer membrane channel protein ECs1865 135 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15834150 Common - tRNA (uracil-5-)-methyltransferase ECs4896 179 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 15830999 Common - OppC ECs1745 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15829323 Common - hypothetical protein ECs0069 146 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15832265 Pathogen - hypothetical protein ECs3011 2 None None None 15830451 Common - NinE ECs1197 2 None None None 162139770 Common - hypothetical protein ECs3182 44 COG1288 COG1288, Predicted membrane protein Function unknown 15831459 Common - putative replication protein ECs2205 5 None None None 38704036 Common - hypothetical protein ECs2692 6 None None None 15832242 Common - regulatory protein CII ECs2988 1 None None None 38704093 Common - hydrogenase 4 membrane subunit ECs3345 80 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 15829976 Common - DNA-binding response regulator in two-component regulatory system with KdpD ECs0722 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15830458 Pathogen - hypothetical protein ECs1204 2 None None None 15832435 Common - phosphate acetyltransferase ECs3181 168 COG0280 Pta, Phosphotransacetylase Energy production and conversion 38704012 Common - hypothetical protein ECs2457 3 None None None 15834180 Common - sensor protein ZraS ECs4926 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15830680 Common mdoG glucan biosynthesis protein G ECs1426 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 15832624 Common - inositol-5-monophosphate dehydrogenase ECs3370 238 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15833844 Pathogen - EspG ECs4590 2 None None None 15832866 Common - hypothetical protein ECs3612 42 None None None 15834229 Pathogen - hypothetical protein ECs4975 1 None None None 15829857 Common - Rhs core protein ECs0603 36 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15833840 Pathogen - hypothetical protein ECs4586 1 None None None 15833507 Common - hypothetical protein ECs4253 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 38704212 Common - hypothetical protein ECs4853 21 COG3074 COG3074, Uncharacterized protein conserved in bacteria Function unknown 162139724 Common - hypothetical protein ECs4321 11 None None None 15831230 Common - hypothetical protein ECs1976 3 None None None 15832045 Common - hypothetical protein ECs2791 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 38704156 Common - putative periplasmic binding transport protein ECs4141 120 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15829577 Common - hypothetical protein ECs0323 5 None None None 15829548 Common - hypothetical protein ECs0294 5 None None None 15830299 Common - hypothetical protein ECs1045 42 COG3304 COG3304, Predicted membrane protein Function unknown 15832921 Common - hypothetical protein ECs3667 71 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 15832539 Common - putative sulfate transport protein CysZ ECs3285 48 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 15833547 Common ggt gamma-glutamyltranspeptidase periplasmic precursor ECs4293 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 15829388 Common - hypothetical protein ECs0134 90 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 38703971 Common - putative filament protein ECs1997 81 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15830792 Pathogen - hypothetical protein ECs1538 1 None None None 15830159 Common - molybdopterin biosynthesis protein MoeA ECs0905 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 15833719 Common - hypothetical protein ECs4465 96 COG3177 COG3177, Uncharacterized conserved protein Function unknown 15832461 Common - 3-oxoacyl-(acyl carrier protein) synthase I ECs3207 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15831722 Common - hypothetical protein ECs2468 3 None None None 15833197 Common - transcriptional activator TtdR ECs3943 166 COG0583 LysR, Transcriptional regulator Transcription 15831816 Common - glucose-6-phosphate 1-dehydrogenase ECs2562 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 15832328 Common - bicyclomycin/multidrug efflux system ECs3074 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 38703998 Pathogen - hypothetical protein ECs5458 1 None None None 15830246 Common - putative heat shock protein ECs0992 133 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15832838 Common - hydrogenase isoenzymes formation protein ECs3584 77 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15833898 Common - tryptophanase leader peptide ECs4644 2 None None None 15830059 Common - hypothetical C4-type zinc finger protein TraR-family ECs0805 9 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15829949 Common lnt apolipoprotein N-acyltransferase ECs0695 165 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 15830357 Common - hypothetical protein ECs1103 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831646 Common - hypothetical protein ECs2392 7 None None None 15831788 Common - hypothetical protein ECs2534 4 None None None 162139795 Common - cytochrome b561 ECs2023 32 COG3038 CybB, Cytochrome B561 Energy production and conversion 15832686 Common era GTP-binding protein Era ECs3432 226 COG1159 Era, GTPase General function prediction only 15834391 Common - putative transport ECs5137 51 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 162139715 Common rpmI 50S ribosomal protein L35 ECs2424 24 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 15831752 Common - hypothetical protein ECs2498 28 COG2707 COG2707, Predicted membrane protein Function unknown 15832337 Common - CcmH precursor ECs3083 88 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 15832967 Common - hypothetical protein ECs3713 1 None None None 15830526 Common - Rtn-like protein ECs1272 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15832772 Common - hypothetical protein ECs3518 8 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 15831400 Common - competence damage-inducible protein A ECs2146 168 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 15829886 Common - isochorismate synthase ECs0632 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 38704082 Common - short chain dehydrogenase ECs3297 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 38704117 Common - putative oxidoreductase ECs3630 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15829478 Common - hypothetical protein ECs0224 43 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 15829836 Common - putative carboxylase ECs0582 5 None None None 15831990 Common - putative terminase small subunit ECs2736 6 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 15830039 Common - galactokinase ECs0785 91 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 15831791 Common - putative regulator ECs2537 124 COG1414 IclR, Transcriptional regulator Transcription 15834260 Common - hypothetical protein ECs5006 9 None None None 15832545 Common - hypothetical protein ECs3291 6 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15830046 Common modB molybdate ABC transporter permease protein ECs0792 226 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 15830288 Common - paraquat-inducible protein A ECs1034 56 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 15831680 Common - threonyl-tRNA synthetase ECs2426 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15831998 Common - putative transposase ECs2744 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832598 Common - hydrogenase 4 subunit B ECs3344 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 15832613 Common - uracil transporter ECs3359 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15834158 Common secE preprotein translocase subunit SecE ECs4904 68 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 15829315 Pathogen - hypothetical protein ECs0061 2 None None None 15833309 Common glmM phosphoglucosamine mutase ECs4055 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15830629 Pathogen - hypothetical protein ECs1375 1 None None None 38704224 Common - sor-operon regulator ECs5004 67 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 38704021 Common - putative transport protein ECs2538 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15833283 Common - hypothetical protein ECs4029 124 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 38703849 Common - hypothetical protein ECs0189 41 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 15833553 Common - glycerol-3-phosphate transporter periplasmic binding protein ECs4299 106 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15830169 Common - hypothetical protein ECs0915 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15832408 Common - hypothetical protein ECs3154 8 COG4575 ElaB, Uncharacterized conserved protein Function unknown 15833337 Common - sugar-specific enzyme IIA component of PTS ECs4083 133 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15830129 Common - ATP-dependent RNA helicase RhlE ECs0875 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15831215 Common - hypothetical protein ECs1961 3 None None None 15831477 Common - hypothetical protein ECs2223 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831701 Common - endonuclease of nucleotide excision repair ECs2447 216 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15829583 Common - hypothetical protein ECs0329 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829945 Common - ATP-binding protein of glutamate/aspartate transport system ECs0691 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15831774 Common - hypothetical protein ECs2520 16 COG3140 COG3140, Uncharacterized protein conserved in bacteria Function unknown 15833780 Common - tRNA guanosine-2'-O-methyltransferase ECs4526 201 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15833765 Common rpmG 50S ribosomal protein L33 ECs4511 137 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 15831354 Common - hypothetical protein ECs2100 16 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15832633 Common - hypothetical protein ECs3379 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 15830834 Pathogen - hypothetical protein ECs1580 1 None None None 15833164 Common - modulator of drug activity B ECs3910 49 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15832321 Common - putative lipoprotein ECs3067 137 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15832945 Common - hypothetical protein ECs3691 194 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 15832910 Common - putative serine transporter ECs3656 37 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15831986 Common - putative head-tail preconnector protein ECs2732 140 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15834037 Common - periplasmic protein disulfide isomerase I ECs4783 67 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15831530 Common - putative replication protein ECs2276 9 None None None 15833291 Common - hypothetical protein ECs4037 93 COG3153 COG3153, Predicted acetyltransferase General function prediction only 15829881 Common - iron-enterobactin transporter ATP-binding protein ECs0627 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 38703914 Pathogen - hypothetical protein ECs1211 2 None None None 162139783 Common - hypothetical protein ECs2577 124 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 162139777 Common gatY tagatose-bisphosphate aldolase ECs2899 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15831592 Common - electron transport complex protein RnfC ECs2338 78 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 15833174 Common - cyclic 3',5'-adenosine monophosphate phosphodiesterase ECs3920 83 COG1409 Icc, Predicted phosphohydrolases General function prediction only 15830708 Common flgE flagellar hook protein FlgE ECs1454 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 15834222 Common - hypothetical protein ECs4968 5 None None None 15831468 Common - putative cell division inhibitor ECs2214 1 None None None 15832385 Common - hypothetical protein ECs3131 55 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15831624 Common - cyclopropane fatty acyl phospholipid synthase ECs2370 135 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 15833047 Common - hypothetical protein ECs3793 85 COG2968 COG2968, Uncharacterized conserved protein Function unknown 15829924 Common - D-alanyl-D-alanine carboxypeptidase fraction A ECs0670 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 38703993 Pathogen - hypothetical protein ECs5446 1 None None None 15832767 Common - putative DNA binding protein ECs3513 37 COG3311 AlpA, Predicted transcriptional regulator Transcription 15830030 Common - peptidoglycan-associated outer membrane lipoprotein ECs0776 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15831407 Common - putative damage-inducible protein ECs2153 10 None None None 15829751 Common - hypothetical protein ECs0497 20 COG0824 FcbC, Predicted thioesterase General function prediction only 15829534 Common - putative tail fiber protein ECs0280 15 None None None 162139805 Common lipB lipoyltransferase ECs0668 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 38704233 Common - hypothetical protein ECs5092 5 None None None 15831322 Common - cryptic nitrate reductase 2 gamma subunit ECs2068 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 15829273 Common - hypothetical protein ECs0019 2 None None None 15832515 Common - putative 2-component transcriptional regulator ECs3261 171 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 15831470 Common - putative exonuclease ECs2216 7 None None None 15829689 Common - hypothetical protein ECs0435 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15830822 Pathogen - hypothetical protein ECs1568 3 None None None 15833093 Common mltC murein transglycosylase C ECs3839 127 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15831542 Common - hypothetical protein ECs2288 80 COG1742 COG1742, Uncharacterized conserved protein Function unknown 15830887 Common - minor capsid protein ECs1633 178 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15831043 Common - putative Dnase ECs1789 5 COG1403 McrA, Restriction endonuclease Defense mechanisms 15833061 Common - putative oxidoreductase ECs3807 107 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15830461 Common - hypothetical protein ECs1207 3 None None None 15830073 Common - endolysin ECs0819 45 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15829651 Common lacZ beta-D-galactosidase ECs0397 70 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 38704251 Common - hypothetical protein ECs5239 110 COG0795 COG0795, Predicted permeases General function prediction only 15834555 Common - hypothetical protein ECs5301 27 COG5464 COG5464, Uncharacterized conserved protein Function unknown 15833757 Common - lipopolysaccharide core biosynthesis protein ECs4503 4 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 15830633 Pathogen - hypothetical protein ECs1379 1 None None None 15833245 Common - putative transport system permease protein ECs3991 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15833363 Common - malate dehydrogenase ECs4109 179 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 15830544 Common - hypothetical protein ECs1290 72 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15831101 Common cysB transcriptional regulator CysB ECs1847 190 COG0583 LysR, Transcriptional regulator Transcription 38704124 Common - dihydropyrimidinase ECs3746 206 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 15830938 Common - D-amino acid dehydrogenase small subunit ECs1684 119 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15833319 Common rplU 50S ribosomal protein L21 ECs4065 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 15830550 Common - hypothetical protein ECs1296 2 None None None 15831629 Common - hypothetical protein ECs2375 13 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 15832871 Common - phosphoadenosine phosphosulfate reductase ECs3617 154 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15831450 Pathogen - hypothetical protein ECs2196 5 None None None 15833072 Common - S-adenosylmethionine synthetase ECs3818 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 15830668 Common - CsgG ECs1414 18 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 15831757 Common - hypothetical protein ECs2503 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 38704111 Pathogen - hypothetical protein ECs3500 4 None None None 15833520 Common - DNA-binding transcriptional repressor ECs4266 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15831492 Common - minor tail protein ECs2238 14 COG4672 gp18, Phage-related protein Function unknown 15831151 Common - putative ATP-binding component of a transport system ECs1897 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 15834020 Common tatA twin argininte translocase protein A ECs4766 51 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 15834204 Pathogen - hypothetical protein ECs4950 1 None None None 15833376 Common - cell wall structural complex MreBCD transmembrane component MreC ECs4122 124 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 15834402 Common hfq RNA-binding protein Hfq ECs5148 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 15832581 Common - transketolase ECs3327 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15830770 Pathogen - hypothetical protein ECs1516 1 None None None 15832883 Common - hypothetical protein ECs3629 194 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15832485 Common - putative prophage Sf6-like integrase ECs3231 111 COG0582 XerC, Integrase DNA replication, recombination, and repair 15830543 Common - putative 3-oxoacyl-[acyl-carrier-protein] synthase synthase ECs1289 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15830983 Common - nitrate reductase 1 alpha subunit ECs1729 114 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 15834013 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase ECs4759 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 15829311 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase ECs0057 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 38703981 Pathogen - hypothetical protein ECs5441 1 None None None 15832148 Common - galactitol-1-phosphate dehydrogenase ECs2894 200 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15833989 Common hemC porphobilinogen deaminase ECs4735 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 162139753 Common aroK shikimate kinase I ECs4232 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 15833772 Common rph ribonuclease PH ECs4518 185 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 15833673 Common - putative transporter protein ECs4419 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15833573 Common - cell developmental protein SirA ECs4319 102 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15833168 Common - putative permease of ferrichrome ABC transporter ECs3914 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15831960 Common - putative 2-component sensor protein ECs2706 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15833389 Common - putative transport protein ECs4135 5 None None None 15834255 Common - sorbose-permease PTS system IIB component ECs5001 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 15833558 Common - branched-chain amino acid transporter permease subunit LivH ECs4304 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 15830974 Common - 2-dehydro-3-deoxyphosphooctonate aldolase ECs1720 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 15832331 Common - 50S ribosomal protein L25 ECs3077 144 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 38704258 Common - hypothetical protein ECs5285 3 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 15832796 Common proX glycine betaine transporter periplasmic subunit ECs3542 50 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 15834274 Common - maltose regulon periplasmic protein ECs5020 17 None None None 15830880 Common - hypothetical protein ECs1626 4 COG5562 COG5562, Phage envelope protein General function prediction only 15830097 Common - putative outer membrane protein precursor ECs0843 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15832789 Common - hypothetical protein ECs3535 85 COG2128 COG2128, Uncharacterized conserved protein Function unknown 15830025 Common - acyl-CoA thioester hydrolase YbgC ECs0771 134 COG0824 FcbC, Predicted thioesterase General function prediction only 15834477 Common - pyrBI operon leader peptide ECs5224 4 None None None 15830471 Common - Bor precursor ECs1217 6 None None None 15832092 Common - fucose synthetase ECs2838 218 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15831174 Common - putative pump protein ECs1920 38 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 15830679 Common mdoC glucans biosynthesis protein ECs1425 23 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 15831618 Common - putative lipoprotein ECs2364 132 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15833567 Common - cell division protein FtsY ECs4313 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 38704222 Pathogen - hypothetical protein ECs5580 1 None None None 15833838 Pathogen - hypothetical protein ECs4584 1 None None None 15831446 Common - hypothetical protein ECs2192 3 None None None 15829726 Pathogen - hypothetical protein ECs0472 2 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15833032 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase ECs3778 124 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 15829767 Common - hemolysin expression-modulating protein ECs0513 12 None None None 15829997 Common - truncated outer membrane protein ECs0743 31 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15830948 Common - molybdenum transport protein ModD ECs1694 198 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 15832765 Common - hypothetical protein ECs3511 16 None None None 15829564 Common - hypothetical protein ECs0310 64 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 38704157 Common - putative transport system permease protein ECs4142 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 38703889 Common - putative transcriptional regulator LYSR-type ECs0796 191 COG0583 LysR, Transcriptional regulator Transcription 15830492 Pathogen - hypothetical protein ECs1238 3 None None None 15834564 Common - hypothetical protein ECs5310 47 None None None 15833276 Common - putative outer membrane protein ECs4022 34 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15831260 Common - putative BigA-like protein ECs2006 134 None None None 15832058 Common - hypothetical protein ECs2804 4 None None None 15830952 Common - putative ABC transporter permease protein ECs1698 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15830185 Common - nitroreductase A ECs0931 79 COG0778 NfnB, Nitroreductase Energy production and conversion 15834294 Common uvrA excinuclease ABC subunit A ECs5040 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 162139738 Common - hypothetical protein ECs4836 75 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 15832298 Common - hypothetical protein ECs3044 48 COG2311 COG2311, Predicted membrane protein Function unknown 15829553 Common - putative DNA binding protein ECs0299 40 COG3311 AlpA, Predicted transcriptional regulator Transcription 15831132 Common - putative oxidoreductase ECs1878 129 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15832429 Common - hypothetical protein ECs3175 35 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 15830377 Common - putative tail fiber protein ECs1123 4 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15830848 Common - hypothetical protein ECs1594 5 None None None 15831013 Common - putative exonuclease ECs1759 10 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15829326 Common tbpA thiamin transporter substrate binding subunit ECs0072 54 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 15830004 Pathogen - hypothetical protein ECs0750 2 None None None 15833633 Common - hypothetical protein ECs4379 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 15829782 Common hemH ferrochelatase ECs0528 158 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 15830274 Common - NAD(P)H-dependent FMN reductase ECs1020 55 COG0431 COG0431, Predicted flavoprotein General function prediction only 15834486 Common - hypothetical protein ECs5232 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 15833713 Common - hypothetical protein ECs4459 32 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 15830662 Common - hypothetical protein ECs1408 3 None None None 15832780 Common - hypothetical protein ECs3526 59 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 15830862 Common - isocitrate dehydrogenase ECs1608 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 15834289 Common alr alanine racemase ECs5035 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 15833195 Common folB bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase ECs3941 54 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 15833460 Common - putative phosphoribulokinase ECs4206 52 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 15832237 Pathogen - hypothetical protein ECs2983 1 None None None 15833320 Common - octaprenyl diphosphate synthase ECs4066 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15830561 Common - hypothetical protein ECs1307 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831074 Common - hypothetical protein ECs1820 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832821 Common - nitric oxide reductase ECs3567 240 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 15829788 Common - hypothetical protein ECs0534 112 COG2606 EbsC, Uncharacterized conserved protein Function unknown 15830962 Common - translation-associated GTPase ECs1708 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 38704178 Common - putative fimbrial chaperone protein precursor ECs4430 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15831763 Common - putative tartrate dehydrogenase ECs2509 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 15830958 Common - dihydroxyacetone kinase ADP-binding subunit ECs1704 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 15832097 Common - putative glycosyl transferase ECs2843 102 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15830109 Common - predicted methyltransferase ECs0855 174 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15833135 Common - hydrogenase 2 protein HybA ECs3881 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15829433 Common - outer membrane protein assembly factor YaeT ECs0179 162 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 15830538 Common - putative holo-[acyl-carrier protein] synthase ECs1284 103 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 15830408 Common - chaperone-modulator protein CbpM ECs1154 18 None None None 15833614 Common - hypothetical protein ECs4360 133 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 38703925 Pathogen - hypothetical protein ECs5413 1 None None None 15832688 Common - lsignal peptidase I ECs3434 203 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15834407 Common - adenylosuccinate synthetase ECs5153 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 15829845 Common - bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase ECs0591 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 15831438 Common - putative lipoprotein Rz1 precursor ECs2183 2 None None None 15833352 Common - N-acetylneuraminate lyase ECs4098 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15829642 Common - putative propionyl-CoA synthetase ECs0388 217 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15834364 Common - hypothetical protein ECs5110 2 None None None 15831581 Common - 7-alpha-hydroxysteroid dehydrogenase ECs2327 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15833620 Common - universal stress protein UspB ECs4366 12 None None None 15829906 Common citG triphosphoribosyl-dephospho-CoA synthase ECs0652 48 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 15834615 Common - hypothetical protein ECs5361 152 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 15829789 Common - putative ligase ECs0535 42 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 15829269 Common - chaperone protein DnaJ ECs0015 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15832608 Common - predicted formate transporter ECs3354 90 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 15831382 Common - altronate oxidoreductase ECs2128 84 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15832084 Common - 6-phosphogluconate dehydrogenase ECs2830 188 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 15832731 Common ppnK inorganic polyphosphate/ATP-NAD kinase ECs3477 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 15830994 Common - thymidine kinase ECs1740 91 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 15830728 Common - 4-amino-4-deoxychorismate lyase ECs1474 163 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15833870 Common - hypothetical protein ECs4616 6 None None None 15833560 Common - hypothetical protein ECs4306 11 None None None 15829736 Common - protoheme IX farnesyltransferase ECs0482 172 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 15830520 Common - hypothetical protein ECs1266 198 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 15829773 Common - hypothetical protein ECs0519 14 None None None 15834386 Common - fumarate reductase subunit D ECs5132 21 COG3080 FrdD, Fumarate reductase subunit D Energy production and conversion 15830487 Common - putative tail tip fiber protein ECs1233 10 COG4733 COG4733, Phage-related protein, tail component Function unknown 38704015 Common - hypothetical lipoprotein ECs2473 32 COG2859 COG2859, Uncharacterized protein conserved in bacteria Function unknown 38704140 Common - hypothetical protein ECs3966 95 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 15829366 Common - putative major pilin subunit ECs0112 36 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 15834143 Common - argininosuccinate lyase ECs4889 234 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 15832768 Common - hypothetical protein ECs3514 7 None None None 15833436 Common rplB 50S ribosomal protein L2 ECs4182 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 15829939 Common - hypothetical protein ECs0685 100 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15830790 Pathogen - hypothetical protein ECs1536 1 None None None 15831514 Common - hypothetical protein ECs2260 2 None None None 15833254 Common - hypothetical protein ECs4000 2 None None None 15830149 Common - hypothetical protein ECs0895 75 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15834496 Common - putative integrase ECs5242 40 None None None 15833584 Common - hypothetical membrane protein ECs4330 25 COG4648 COG4648, Predicted membrane protein Function unknown 15831909 Common - putative amino-acid ABC transporter ATP-binding protein YecC ECs2655 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15834100 Common - hypothetical protein ECs4846 22 COG3152 COG3152, Predicted membrane protein Function unknown 15831053 Common - hypothetical protein ECs1799 2 None None None 15831731 Common - putative transposase ECs2477 29 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832961 Common - hypothetical protein ECs3707 2 None None None 15829464 Common rnhA ribonuclease H ECs0210 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 15833255 Common - hypothetical protein ECs4001 2 None None None 15834182 Common - phosphoribosylamine--glycine ligase ECs4928 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 15834547 Common - putative transport protein ECs5293 61 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830388 Common - putative third cytochrome oxidase subunit I ECs1134 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 15830601 Common - hypothetical protein ECs1347 24 None None None 15833438 Common rplD 50S ribosomal protein L4 ECs4184 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 15834308 Common - NrfC ECs5054 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15834372 Common - divalent-cation tolerance protein CutA ECs5118 101 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 15829989 Common - putative hydrolase-oxidase ECs0735 101 COG0327 COG0327, Uncharacterized conserved protein Function unknown 15833610 Common - HicB-like protein ECs4356 10 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 15829350 Common ddl D-alanine--D-alanine ligase ECs0096 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 15834056 Common - putative aldose-1-epimerase ECs4802 61 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 15834080 Common - fructose-specific PTS system enzyme IIA component ECs4826 114 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15830308 Common - hypothetical protein ECs1054 130 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 15829260 Common - hypothetical protein ECs0006 86 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 15833203 Common dnaG DNA primase ECs3949 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15831018 Pathogen - hypothetical protein ECs1764 1 None None None 15832020 Common - putative repressor protein ECs2766 26 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15834442 Common - putative transmembrane subunit ECs5188 40 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 38703880 Common - hypothetical protein ECs5382 27 COG2879 COG2879, Uncharacterized small protein Function unknown 15830499 Common - MokW ECs1245 5 None None None 15833929 Common - F0F1 ATP synthase subunit gamma ECs4675 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 15830176 Common - proton motive force efflux pump ECs0922 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830370 Common - putative minor tail protein ECs1116 14 COG4672 gp18, Phage-related protein Function unknown 15831529 Common - putative replication protein ECs2275 75 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 15833915 Common - phosphate transporter subunit ECs4661 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 15834347 Common - proline/glycine betaine transporter ECs5093 163 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830468 Common - putative antirepressor protein ECs1214 8 None None None 38704260 Common - hypothetical protein ECs5298 35 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 15830037 Common - phosphoglyceromutase ECs0783 162 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 15832863 Common - hypothetical protein ECs3609 46 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 15830757 Common - hypothetical protein ECs1503 8 None None None 15833646 Common - hypothetical protein ECs4392 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15834568 Pathogen - hypothetical protein ECs5314 2 None None None 15832917 Common - L-fuculokinase ECs3663 182 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15832828 Common - formate hydrogenlyase maturation protein ECs3574 13 None None None 15833185 Common - glycogen synthesis protein GlgS ECs3931 5 None None None 15834059 Common - putative dehydrogenase ECs4805 161 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 15830102 Pathogen - hypothetical protein ECs0848 3 None None None 15830237 Common - putative MFS family transporter protein ECs0983 101 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 38704031 Pathogen - hypothetical protein ECs5465 1 None None None 15831760 Common - hypothetical protein ECs2506 16 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 15831539 Common - hypothetical protein ECs2285 4 None None None 15834612 Common - hypothetical protein ECs5358 29 COG4452 CreD, Inner membrane protein involved in colicin E2 resistance Defense mechanisms 15830080 Common - hypothetical protein ECs0826 4 None None None 162139781 Common - transcriptional regulatory protein YedW ECs2707 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15834174 Common hemE uroporphyrinogen decarboxylase ECs4920 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 15833952 Common - transcriptional regulator HdfR ECs4698 184 COG0583 LysR, Transcriptional regulator Transcription 15829256 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I ECs0002 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15830584 Common rpmE2 50S ribosomal protein L31 type B ECs1330 101 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15832611 Common - putative oxidoreductase ECs3357 112 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 15833348 Common - hypothetical protein ECs4094 29 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 15831522 Common - putative crossover junction endodeoxyribonuclease ECs2268 7 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 15832185 Common - hypothetical protein ECs2931 6 None None None 15834544 Common - putative invasin ECs5290 90 None None None 15834434 Common - hypothetical protein ECs5180 2 None None None 15833290 Common - hypothetical protein ECs4036 74 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 15830348 Pathogen - hypothetical protein ECs1094 1 None None None 15832496 Common - aminoimidazole riboside kinase ECs3242 180 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15829952 Common - putative ATP-binding protein in pho regulon ECs0698 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 15833778 Common rpoZ DNA-directed RNA polymerase subunit omega ECs4524 110 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 38704107 Common - hypothetical protein ECs3449 40 COG3148 COG3148, Uncharacterized conserved protein Function unknown 15830365 Common - hypothetical protein ECs1111 6 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15830744 Common - hypothetical protein ECs1490 11 None None None 15832471 Common - putative fimbrial-like protein ECs3217 14 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 38704147 Common greA transcription elongation factor GreA ECs4060 204 COG0782 GreA, Transcription elongation factor Transcription 15831931 Common fliF flagellar MS-ring protein ECs2677 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 15831241 Common - putative tail assembly protein ECs1987 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 15831842 Common - flagellar protein ECs2588 10 None None None 15830766 Pathogen - hypothetical protein ECs1512 3 None None None 15833223 Common - hypothetical protein ECs3969 136 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15829703 Common - DNA-binding response regulator in two-component regulatory system with PhoR (or CreC) ECs0449 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15831532 Pathogen - hypothetical protein ECs2278 6 COG4197 COG4197, Uncharacterized protein conserved in bacteria, prophage-related Function unknown 15832983 Pathogen - EivI ECs3729 2 None None None 15832618 Common - exopolyphosphatase ECs3364 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 15829418 Common dgt deoxyguanosinetriphosphate triphosphohydrolase ECs0164 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 15833948 Common - ribokinase ECs4694 198 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15831045 Common - putative terminase small subunit ECs1791 4 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 15833282 Common - putative glycosylase ECs4028 40 COG3107 LppC, Putative lipoprotein General function prediction only 15831825 Common ruvA Holliday junction DNA helicase motor protein ECs2571 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 15834036 Common - predicted kinase ECs4782 50 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 38704048 Common - putative chaperonin ECs2879 18 COG4248 COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains General function prediction only 15832217 Common - putative terminase large subunit ECs2963 35 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 15833999 Common - hypothetical protein ECs4745 24 COG3698 COG3698, Predicted periplasmic protein Function unknown 15831999 Common - putative transposase ECs2745 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829255 Pathogen - thr operon leader peptide ECs0001 1 None None None 15830784 Common - putative holin ECs1530 5 None None None 15832411 Common - deubiquitinase ECs3157 2 None None None 15833515 Common - hypothetical protein ECs4261 27 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 15831371 Common - predicted lipoprotein ECs2117 76 None None None 15833941 Common yieM hypothetical protein ECs4687 28 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 15830762 Common - hypothetical protein ECs1508 5 None None None 15832550 Common - thiosulfate transporter subunit ECs3296 88 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 15832027 Common - putative integrase ECs2773 30 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15831620 Common - putative transport protein ECs2366 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15831738 Common - putative transport protein ECs2484 128 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15833263 Common - DNA-binding transcriptional dual regulator ECs4009 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 38704075 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase ECs3208 92 COG4121 COG4121, Uncharacterized conserved protein Function unknown 38703946 Common - hypothetical protein ECs1674 35 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 15832019 Pathogen - putative cell division control protein ECs2765 1 None None None 15832710 Common - hypothetical protein ECs3456 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 15833781 Common - ATP-dependent DNA helicase RecG ECs4527 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 15833455 Common - glutathione-regulated potassium-efflux system protein KefB ECs4201 198 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15830944 Common - putative transposase ECs1690 33 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833401 Common aroE shikimate 5-dehydrogenase ECs4147 219 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 15830598 Common - hypothetical protein ECs1344 14 None None None 15832353 Common - malate:quinone oxidoreductase ECs3099 57 COG0579 COG0579, Predicted dehydrogenase General function prediction only 15830904 Common - putative tail fiber protein ECs1650 15 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15832719 Common - hypothetical protein ECs3465 6 None None None 15833819 Pathogen - SepQ ECs4565 1 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15830156 Common - putative pyruvate formate-lyase 2 activating enzyme ECs0902 60 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15829563 Common - putative transcriptional regulator ECs0309 182 COG0583 LysR, Transcriptional regulator Transcription 15830313 Common - putative cell division inhibition protein ECs1059 1 None None None 15831639 Common - hypothetical protein ECs2385 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 15833005 Common - putative oxidoreductase Fe-S subunit ECs3751 208 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 15832682 Common - hypothetical protein ECs3428 103 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15834238 Common - putative tail protein ECs4984 21 COG4379 COG4379, Mu-like prophage tail protein gpP General function prediction only 15833533 Common - putative eubacterial dITP- and XTP- hydrolyzing enzyme ECs4279 148 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 38703891 Common - hypothetical protein ECs5398 10 None None None 15831389 Common - sugar efflux transporter ECs2135 150 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832853 Common truD tRNA pseudouridine synthase D ECs3599 86 COG0585 COG0585, Uncharacterized conserved protein Function unknown 15832748 Common - hypothetical protein ECs3494 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833238 Common - putative transferase ECs3984 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15831664 Common - hypothetical protein ECs2410 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 15831248 Pathogen - hypothetical protein ECs1994 2 None None None 15831714 Common - hypothetical protein ECs2460 28 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 15833826 Pathogen - hypothetical protein ECs4572 1 None None None 15832720 Common - hypothetical protein ECs3466 15 None None None 15831204 Pathogen - hypothetical protein ECs1950 5 None None None 15831896 Pathogen - putative phage tail protein ECs2642 4 None None None 15833445 Common - elongation factor G ECs4191 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 162139802 Common - hybrid sensory histidine kinase TorS ECs1148 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15832794 Common - glycine betaine transporter ATP-binding subunit ECs3540 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 15833144 Common - biopolymer transport protein ExbB ECs3890 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15829794 Common - putative outer membrane transport protein ECs0540 105 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15833727 Common - hypothetical protein ECs4473 139 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15830795 Common - putative terminase small subunit ECs1541 4 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 15829672 Common - putative transcription regulator ECs0418 186 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15830391 Common - cryptic autophosphorylating protein tyrosine kinase Etk ECs1137 154 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 15832943 Common - putative transport protein ECs3689 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15833739 Common cysE serine acetyltransferase ECs4485 212 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 15834001 Common - hypothetical protein ECs4747 7 None None None 15831034 Common - putative DNA methylase ECs1780 96 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15833852 Common - putative DNA-binding protein ECs4598 42 COG2944 COG2944, Predicted transcriptional regulator Transcription 15829287 Common - ribonucleoside hydrolase RihC ECs0033 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 38704056 Pathogen - hypothetical protein ECs5482 3 None None None 15832277 Common - hypothetical protein ECs3023 32 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15831883 Pathogen - hypothetical protein ECs2629 1 None None None 15830078 Common - hypothetical protein ECs0824 4 None None None 15829670 Common - putative regulatory protein ECs0416 71 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15829633 Common - putative oxidoreductase ECs0379 192 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 15834534 Common - fructuronate transporter ECs5280 89 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 15831759 Common - hypothetical protein ECs2505 5 None None None 15831395 Common - putative MFS-type transporter YdeE ECs2141 50 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15831378 Common - aldolase ECs2124 77 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 15829493 Pathogen - hypothetical protein ECs0239 1 None None None 15832398 Common - hypothetical protein ECs3144 19 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15830568 Common - hypothetical protein ECs1314 4 None None None 15832933 Common recC exonuclease V subunit gamma ECs3679 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 15834411 Common - hypothetical protein ECs5157 13 COG3789 COG3789, Uncharacterized protein conserved in bacteria Function unknown 15833883 Common - hypothetical protein ECs4629 12 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 15830263 Common - hypothetical protein ECs1009 63 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 38703904 Common - hypothetical protein ECs0996 126 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 15833805 Common - hypothetical protein ECs4551 2 None None None 15833749 Common - 2-amino-3-ketobutyrate coenzyme A ligase ECs4495 191 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 15834166 Common - HtrC ECs4912 2 None None None 38703942 Pathogen - hypothetical protein ECs1589 2 None None None 15832225 Pathogen - hypothetical protein ECs2971 1 None None None 15830714 Common flgK flagellar hook-associated protein FlgK ECs1460 125 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 15833487 Common - predicted fimbrial transporter ECs4233 142 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 15833801 Common - hypothetical protein ECs4547 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830693 Common - DNA damage-inducible protein I ECs1439 12 None None None 38704000 Common - putative oxidoreductase ECs2332 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15833364 Common - arginine repressor ECs4110 75 COG1438 ArgR, Arginine repressor Transcription 15829512 Common - DNA polymerase IV ECs0258 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 15834353 Common - biodegradative arginine decarboxylase ECs5099 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 15832800 Common - transcriptional repressor MprA ECs3546 89 COG1846 MarR, Transcriptional regulators Transcription 15834214 Common - hypothetical protein ECs4960 19 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 15831079 Pathogen - bfpT-regulated chaperone-like protein ECs1825 2 None None None 15833027 Common - 6-phospho-beta-glucosidase A ECs3773 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 15833218 Common - hypothetical protein ECs3964 16 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 15830481 Pathogen - hypothetical protein ECs1227 4 None None None 15833600 Common nikD nickel transporter ATP-binding protein ECs4346 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15831068 Pathogen - hypothetical protein ECs1814 3 None None None 38704086 Common - hypothetical protein ECs3309 5 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 15830322 Common - hypothetical protein ECs1068 5 None None None 15833108 Pathogen - hypothetical protein ECs3854 2 None None None 15832902 Common - putative glucarate dehydratase ECs3648 52 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 15833653 Common treF trehalase ECs4399 30 COG1626 TreA, Neutral trehalase Carbohydrate transport and metabolism 15829526 Pathogen - putative transcription antitermination protein ECs0272 1 None None None 15832603 Common - hydrogenase 4 subunit ECs3349 197 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 38704026 Common - biotin sulfoxide reductase 2 ECs2582 170 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15832172 Common - hypothetical protein ECs2918 4 None None None 15832678 Common - putative transglycosylase ECs3424 92 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 15833742 Common - glutaredoxin 3 ECs4488 132 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 15834231 Common - hypothetical protein ECs4977 4 COG5003 COG5003, Mu-like prophage protein gp37 General function prediction only 15830876 Common - putative endolysin ECs1622 19 COG4678 COG4678, Muramidase (phage lambda lysozyme) Carbohydrate transport and metabolism 15833905 Common - putative membrane/transport protein ECs4651 134 COG2252 COG2252, Permeases General function prediction only 15829359 Common - zinc-binding protein ECs0105 60 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 15829624 Common - hypothetical protein ECs0370 17 None None None 15832833 Common - formate hydrogenlyase subunit 3 ECs3579 206 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 15833863 Pathogen - hypothetical protein ECs4609 1 None None None 15830750 Common - outer membrane-specific lipoprotein transporter subunit LolE ECs1496 183 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15829930 Common - PhpB ECs0676 175 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 15834315 Common - selenopolypeptide subunit of formate dehydrogenase H ECs5061 199 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 38704073 Common - phosphodiesterase ECs3184 46 COG0622 COG0622, Predicted phosphoesterase General function prediction only 15833812 Common - EscD ECs4558 8 None None None 15832341 Common - heme exporter protein C ECs3087 4 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 15829669 Common - putative periplasmic-iron-binding protein ECs0415 123 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 15832809 Common recX recombination regulator RecX ECs3555 67 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 15830294 Common - hypothetical protein ECs1040 17 COG3120 COG3120, Uncharacterized protein conserved in bacteria Function unknown 15832989 Pathogen - hypothetical protein ECs3735 1 None None None 15833303 Common infB translation initiation factor IF-2 ECs4049 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 15834337 Common phnH carbon-phosphorus lyase complex subunit ECs5083 42 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 15833136 Common - hydrogenase 2 small subunit ECs3882 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 38704187 Common - hypothetical protein ECs4521 114 COG2860 COG2860, Predicted membrane protein Function unknown 15829489 Common - hypothetical protein ECs0235 1 None None None 15829730 Common - exodeoxyribonuclease VII small subunit ECs0476 141 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 15832646 Common hscA chaperone protein HscA ECs3392 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15833180 Common - putative synthetase/amidase ECs3926 54 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 162139707 Common dsbG disulfide isomerase/thiol-disulfide oxidase ECs0643 28 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15830657 Common - putative DNA repair protein ECs1403 173 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 15832244 Common - putative prophage repressor CI ECs2990 28 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15830815 Pathogen - hypothetical protein ECs1561 2 None None None 15830933 Common umuC DNA polymerase V subunit UmuC ECs1679 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 15829800 Common - hypothetical lipoprotein ECs0546 3 None None None 15833842 Common - Ler ECs4588 12 COG2916 Hns, DNA-binding protein H-NS General function prediction only 15830650 Common - AidA-I ECs1396 112 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15831058 Common - minor tail protein ECs1804 7 COG4718 COG4718, Phage-related protein Function unknown 15833846 Pathogen - hypothetical protein ECs4592 1 None None None 15834173 Common nudC NADH pyrophosphatase ECs4919 108 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 15832571 Common - EutE ECs3317 179 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 162139728 Common - nicotinamide-nucleotide adenylyltransferase ECs5348 31 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 15833189 Common - bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase ECs3935 180 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 15830006 Common - dihydrolipoamide acetyltransferase ECs0752 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 38703916 Common - putative transport protein ECs1252 129 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15832072 Common - hypothetical protein of sugar metabolism ECs2818 97 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15829694 Common - hypothetical protein ECs0440 14 None None None 15832777 Common - 4-aminobutyrate aminotransferase ECs3523 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 15833423 Common rplR 50S ribosomal protein L18 ECs4169 209 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 15830329 Pathogen - hypothetical protein ECs1075 4 None None None 15833698 Common - hypothetical protein ECs4444 27 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 15831266 Common - hypothetical protein ECs2012 72 COG2267 PldB, Lysophospholipase Lipid metabolism 15833588 Common - hypothetical protein ECs4334 60 COG0824 FcbC, Predicted thioesterase General function prediction only 15834210 Pathogen - hypothetical protein ECs4956 1 None None None 15829303 Common - glutathione-regulated potassium-efflux system ancillary protein KefF ECs0049 75 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15832371 Common - ribonucleotide-diphosphate reductase subunit alpha ECs3117 206 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15834468 Common nrdG anaerobic ribonucleotide reductase-activating protein ECs5214 63 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 38704219 Common - sulfur carrier protein ThiS ECs5575 23 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 15830203 Pathogen - hypothetical protein ECs0949 2 None None None 15830691 Common solA N-methyltryptophan oxidase ECs1437 49 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15833049 Common - mechanosensitive channel MscS ECs3795 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15832451 Common - colicin V production protein ECs3197 103 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 15831117 Common - putative multidrug-efflux transport protein precursor ECs1863 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15833549 Common ugpQ cytoplasmic glycerophosphodiester phosphodiesterase ECs4295 155 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 15830980 Common - DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) ECs1726 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15833865 Common - acetolactate synthase 1 regulatory subunit ECs4611 124 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 15830682 Common - predicted lipoprotein ECs1428 9 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 15834219 Common - C4-type zinc finger protein (TraR family) ECs4965 6 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15832428 Common - aminotransferase AlaT ECs3174 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15830923 Common - cell division inhibitor MinD ECs1669 148 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 15829276 Common - putative outer membrane usher protein precursor ECs0022 30 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15834015 Common - uridine phosphorylase ECs4761 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 15830118 Common - hypothetical protein ECs0864 124 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 15832940 Common - fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain ECs3686 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 15832756 Common - putative serine/threonine protein phosphatase ECs3502 104 None None None 15830473 Common - putative small subunit terminase ECs1219 10 None None None 15834461 Common - putative transport system permease protein ECs5207 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 15829753 Common - hypothetical protein ECs0499 37 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 15832744 Common - putative transposase ECs3490 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 38704174 Pathogen - hypothetical protein ECs5533 1 None None None 38704038 Pathogen - hypothetical protein ECs5470 1 None None None 38703921 Common - putative oxidoreductase ECs1275 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15833511 Common - gluconate permease ECs4257 77 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 15834479 Common - hypothetical protein ECs5225 77 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15834067 Pathogen - hypothetical protein ECs4813 2 None None None 15832256 Common - exonuclease ECs3002 13 None None None 15830456 Common - hypothetical protein ECs1202 3 None None None 15832923 Common - hypothetical protein ECs3669 13 None None None 15831221 Common - hypothetical protein ECs1967 1 None None None 15832864 Common - hypothetical protein ECs3610 25 None None None 38704014 Common - putative thiosulfate sulfur transferase ECs2463 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15829837 Common - carbamate kinase ECs0583 66 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 15834134 Common - predicted formate acetyltransferase 2 (pyruvate formate lyase II) ECs4880 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 15830509 Common - putative acetyltransferase ECs1255 64 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15830385 Common - hydrogenase 1 maturation protease ECs1131 77 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 15832532 Common gltX glutamyl-tRNA synthetase ECs3278 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 38704091 Common gcvR glycine cleavage system transcriptional repressor ECs3341 31 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 15831691 Common - cell division modulator ECs2437 6 None None None 15834492 Common - hypothetical protein ECs5238 74 COG0795 COG0795, Predicted permeases General function prediction only 38704264 Common - hypothetical protein ECs5328 9 None None None 15834267 Common - phosphate-starvation-inducible protein PsiE ECs5013 21 COG3223 COG3223, Predicted membrane protein Function unknown 15829974 Common - putrescine transport protein ECs0720 176 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15832267 Common - putative integrase ECs3013 95 COG0582 XerC, Integrase DNA replication, recombination, and repair 15829830 Common - glycerate kinase II ECs0576 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 15833821 Pathogen - hypothetical protein ECs4567 1 None None None 15833499 Common - phosphoenolpyruvate carboxykinase ECs4245 96 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 15833469 Common - hypothetical protein ECs4215 61 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 15831360 Common - putative oxidoreductase major subunit ECs2106 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15834141 Common argC N-acetyl-gamma-glutamyl-phosphate reductase ECs4887 216 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 15829821 Common - DNA-binding transcriptional repressor ECs0567 122 COG1414 IclR, Transcriptional regulator Transcription 15834358 Common - fumarase B ECs5104 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15830018 Common - methylaspartate mutase subunit S ECs0764 46 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 15832904 Common - flavodoxin ECs3650 69 COG0716 FldA, Flavodoxins Energy production and conversion 15833914 Common - transcriptional regulator PhoU ECs4660 194 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 38704256 Common - FimC ECs5275 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 38704150 Common - N-acetylmannosamine kinase ECs4095 100 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 38703961 Common pspF phage shock protein operon transcriptional activator ECs1880 170 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 15830567 Common - hypothetical protein ECs1313 5 None None None 15832284 Common - putative gentisate 1,2-dioxygenase ECs3030 32 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 15833664 Common - putative oxidoreductase subunit ECs4410 66 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15830500 Pathogen - hypothetical protein ECs1246 5 None None None 15831267 Common - hypothetical protein ECs2013 24 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 38704168 Common livF leucine/isoleucine/valine transporter ATP-binding subunit ECs4301 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 15829649 Common lacA galactoside O-acetyltransferase ECs0395 215 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15833113 Common - hypothetical protein ECs3859 39 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834546 Common - hypothetical protein ECs5292 2 None None None 15831272 Pathogen - hypothetical protein ECs2018 2 None None None 15829961 Common nagA N-acetylglucosamine-6-phosphate deacetylase ECs0707 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 38704044 Pathogen - hypothetical protein ECs5479 1 None None None 15832798 Common - hypothetical protein ECs3544 104 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 15832502 Common - DNA-binding response regulator in two-component regulatory system with EvgS ECs3248 142 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15833378 Common - regulatory protein CsrD ECs4124 151 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15834097 Common - CDP-diacylglycerol pyrophosphatase ECs4843 19 COG2134 Cdh, CDP-diacylglycerol pyrophosphatase Lipid metabolism 15834018 Common - hypothetical protein ECs4764 29 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 15830195 Common - putative PTS system enzyme IIB ECs0941 8 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 15832006 Common - hypothetical protein ECs2752 6 None None None 38704138 Common - hypothetical protein ECs3930 51 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 15834359 Common - anaerobic C4-dicarboxylate transporter ECs5105 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 15831674 Common pheT phenylalanyl-tRNA synthetase subunit beta ECs2420 245 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 15831806 Common - DNA polymerase III subunit theta ECs2552 12 None None None 15830414 Common - putative integrase ECs1160 92 COG0582 XerC, Integrase DNA replication, recombination, and repair 15830231 Common - recombination factor protein RarA ECs0977 240 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 15832339 Common - cytochrome c-type biogenesis protein ECs3085 160 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 38703853 Common - putative reductase ECs0338 169 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 15833500 Common envZ osmolarity sensor protein ECs4246 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15829969 Common - flavodoxin FldA ECs0715 74 COG0716 FldA, Flavodoxins Energy production and conversion 15830850 Pathogen - hypothetical protein ECs1596 2 None None None 15833975 Common - dTDP-glucose 4,6-dehydratase ECs4721 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 15829482 Common - hypothetical protein ECs0228 44 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 15830906 Common - putative catalase ECs1652 47 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 15834087 Common - positive regulator for rhaRS operon ECs4833 116 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15830659 Common - hypothetical protein ECs1405 10 None None None 15829747 Common - DNA-binding ATP-dependent protease La ECs0493 216 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 162139750 Common gntK gluconate kinase 1 ECs4286 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 15833625 Common - hypothetical protein ECs4371 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 15834476 Common pyrB aspartate carbamoyltransferase catalytic subunit ECs5222 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 15830412 Common - glucose-1-phosphatase/inositol phosphatase ECs1158 17 None None None 15829309 Common apaG ApaG ECs0055 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 15833751 Common rfaD ADP-L-glycero-D-mannoheptose-6-epimerase ECs4497 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15831104 Common ribA GTP cyclohydrolase II ECs1850 193 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 15833599 Common nikC nickel transporter permease NikC ECs4345 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15830971 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase ECs1717 213 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15830331 Common - hypothetical protein ECs1077 20 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 15834115 Common - DNA-binding transcriptional regulator CytR ECs4861 127 COG1609 PurR, Transcriptional regulators Transcription 38704059 Common - DNA-binding transcriptional activator of stationary phase nitrogen survival ECs3055 17 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15831189 Common - hypothetical protein ECs1935 3 None None None 15832691 Common rseB periplasmic negative regulator of sigmaE ECs3437 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 15833668 Common - hypothetical protein ECs4414 12 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15831859 Common - trehalose-6-phosphate phosphatase ECs2605 90 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 15832658 Common - phenylpropionate dioxygenase large terminal subunit ECs3404 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 15833344 Common - hypothetical protein ECs4090 86 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 15833592 Common - 3-oxoacyl-(acyl carrier protein) synthase I ECs4338 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15829393 Pathogen - putative fimbrial protein ECs0139 3 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15830619 Pathogen - hypothetical protein ECs1365 1 None None None 15831563 Common pntA NAD(P) transhydrogenase subunit alpha ECs2309 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 15831343 Common - ATP-dependent peptide transporter membrane subunit ECs2089 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15832700 Common - uracil-DNA glycosylase ECs3446 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 15830134 Common - hypothetical protein ECs0880 11 None None None 15832104 Common - putative pyruvyl transferase ECs2850 23 COG2327 WcaK, Uncharacterized conserved protein Function unknown 15830593 Common - hypothetical protein ECs1339 60 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831594 Common - electron transport complex protein RnfG ECs2340 58 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 15829411 Common - iron-hydroxamate transporter permease subunit ECs0157 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15829275 Common - hypothetical protein ECs0021 1 None None None 15833857 Common uhpT sugar phosphate antiporter ECs4603 47 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15831440 Common - putative endolysin ECs2186 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15834049 Common - hypothetical protein ECs4795 10 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 38704236 Common - lysyl-tRNA synthetase ECs5136 221 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15831124 Common - homolog of Salmonella peptide transport permease protein ECs1870 218 COG4168 SapB, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 15831864 Common - ferritin-like protein ECs2610 73 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 15831257 Common - hypothetical protein ECs2003 15 None None None 15834504 Common - hypothetical protein ECs5250 3 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 15834023 Common - DNase TatD ECs4769 229 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15832378 Common glpQ glycerophosphodiester phosphodiesterase ECs3124 116 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 15832369 Common - 3-demethylubiquinone-9 3-methyltransferase ECs3115 173 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 15832383 Common - hypothetical protein ECs3129 30 COG5464 COG5464, Uncharacterized conserved protein Function unknown 15833152 Common - hypothetical protein ECs3898 3 None None None 15830857 Common - adenylosuccinate lyase ECs1603 230 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 15830896 Pathogen - minor tail protein ECs1642 3 None None None 15829739 Common - cytochrome o ubiquinol oxidase subunit I ECs0485 165 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 15832311 Common - hypothetical protein ECs3057 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 15830281 Common - putative fimbrial-like protein ECs1027 11 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15831324 Common - cryptic nitrate reductase 2 beta subunit ECs2070 150 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 162139807 Common - fructokinase ECs0444 161 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15829545 Common - hypothetical protein ECs0291 9 None None None 15833425 Common rpsH 30S ribosomal protein S8 ECs4171 242 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 15829628 Common - putative sugar-binding protein ECs0374 81 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 162139779 Common - uridine kinase ECs2873 99 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 15831409 Pathogen - hypothetical protein ECs2155 2 None None None 15831026 Common - putative colonization factor ECs1772 16 COG4588 AcfC, Accessory colonization factor AcfC, contains ABC-type periplasmic domain General function prediction only 15834236 Common - putative tape measure protein ECs4982 7 COG3941 COG3941, Mu-like prophage protein General function prediction only 15831305 Common - hypothetical protein ECs2051 37 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 15833063 Common - predicted mannitol-specific enzyme IIA component of PTS ECs3809 39 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15833607 Common - putative sugar kinase ECs4353 176 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15831571 Common fumC fumarate hydratase ECs2317 215 COG0114 FumC, Fumarase Energy production and conversion 15831919 Common - flagellar biosynthesis protein FliT ECs2665 10 None None None 15831789 Common - hypothetical protein ECs2535 8 None None None 15831622 Common - putative DNA-binding transcriptional regulator ECs2368 163 COG0583 LysR, Transcriptional regulator Transcription 15832431 Common - putative phosphatase ECs3177 147 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 38704116 Common - hypothetical protein ECs3621 109 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15831452 Common - MokW ECs2198 5 None None None 15829455 Common metN DL-methionine transporter ATP-binding subunit ECs0201 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 15831508 Common - putative Dnase ECs2254 5 COG1403 McrA, Restriction endonuclease Defense mechanisms 15834269 Common malG maltose transporter permease ECs5015 182 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 15829933 Common - LPS-assembly lipoprotein RplB ECs0679 29 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 15830805 Common - putative phage tail protein ECs1551 3 None None None 15831490 Common - putative tail assembly protein ECs2236 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 15829718 Common - TSX ECs0464 18 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 15830440 Common - CRO ECs1186 7 COG1476 COG1476, Predicted transcriptional regulators Transcription 15830889 Common - major capsid protein ECs1635 10 None None None 15829313 Common - organic solvent tolerance protein ECs0059 114 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 15832024 Common - hypothetical protein ECs2770 10 None None None 15832583 Common - hypothetical protein ECs3329 156 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15834553 Common - hypothetical protein ECs5299 49 COG2733 COG2733, Predicted membrane protein Function unknown 15830985 Common - nitrate reductase 1 delta subunit ECs1731 54 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 15831481 Pathogen - hypothetical protein ECs2227 1 None None None 15831503 Pathogen - hypothetical protein ECs2249 1 None None None 15830997 Common - oligopeptide transport periplasmic binding protein ECs1743 208 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15832477 Common - phosphohistidine phosphatase ECs3223 51 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 15833675 Common dppD dipeptide transporter ATP-binding subunit ECs4421 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15833190 Common - bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase ECs3936 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 15833574 Common - hypothetical protein ECs4320 83 COG1738 COG1738, Uncharacterized conserved protein Function unknown 15831369 Common - hypothetical protein ECs2115 42 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 15830631 Common - hypothetical protein ECs1377 3 None None None 15833554 Common - hypothetical protein ECs4300 10 COG4700 COG4700, Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats Function unknown 15834273 Common lamB maltoporin ECs5019 26 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 15833518 Common - hypothetical protein ECs4264 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 15833967 Common - ATP-dependent RNA helicase RhlB ECs4713 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15829866 Common - copper/silver efflux system membrane fusion protein CusB ECs0612 127 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15830702 Common - FlgN ECs1448 12 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 38703954 Pathogen - hypothetical protein ECs5431 1 None None None 15834404 Common - FtsH protease regulator HflK ECs5150 214 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15833101 Common - hypothetical protein ECs3847 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834513 Common - hypothetical protein ECs5259 8 None None None 15832929 Common - N-acetylglutamate synthase ECs3675 203 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 15831811 Common - hypothetical protein ECs2557 8 None None None 15832487 Common - putative DNA transfer protein precursor ECs3233 4 None None None 15830989 Common - hypothetical protein ECs1735 88 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 15834042 Common - hypothetical protein ECs4788 21 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 15830642 Pathogen - putative transcriptional regulator ECs1388 2 None None None 15833172 Common - DNA topoisomerase IV subunit B ECs3918 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15834220 Common - hypothetical protein ECs4966 5 None None None 162139751 Common - gluconate periplasmic binding protein ECs4254 158 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 15829872 Common - hypothetical protein ECs0618 6 None None None 15833003 Common - hypothetical protein ECs3749 20 None None None 15831900 Common - putative tail protein ECs2646 19 COG3500 COG3500, Phage protein D General function prediction only 15831182 Common - C32 tRNA thiolase ECs1928 164 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15834187 Common - isocitrate lyase ECs4933 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 162139749 Common - hypothetical protein ECs4322 55 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830210 Common - L-allo-threonine aldolase, PLP-dependent ECs0956 111 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 162139740 Common dapF diaminopimelate epimerase ECs4739 202 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 15832215 Common - putative portal protein ECs2961 34 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 15832791 Common nrdI ribonucleotide reductase stimulatory protein ECs3537 39 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 15830215 Common - aquaporin Z ECs0961 98 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 15831310 Common - putative receptor ECs2056 51 COG3391 COG3391, Uncharacterized conserved protein Function unknown 15831511 Common - lipoprotein Rz1 precursor ECs2256 1 None None None 15831947 Common - mannosyl-3-phosphoglycerate phosphatase ECs2693 30 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 15829306 Common - CcdA-like protein ECs0052 9 COG5302 COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid General function prediction only 15833767 Common radC DNA repair protein RadC ECs4513 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 15831244 Common - putative host specificity protein ECs1990 18 COG4733 COG4733, Phage-related protein, tail component Function unknown 15831772 Common - hypothetical protein ECs2518 106 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15830699 Common - hypothetical protein ECs1445 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 15830045 Common modA molybdate transporter periplasmic protein ECs0791 161 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 15829374 Common lpdA dihydrolipoamide dehydrogenase ECs0120 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15830780 Pathogen - hypothetical protein ECs1525 1 None None None 15829971 Common - hypothetical protein ECs0717 139 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15831660 Common - flavoprotein ECs2406 117 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15831465 Pathogen - hypothetical protein ECs2211 1 None None None 15834192 Common - putative alpha helix protein ECs4938 80 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 15830124 Common - hypothetical protein ECs0870 183 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 162139717 Common znuA high-affinity zinc transporter periplasmic component ECs2567 163 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15829741 Common ampG muropeptide transporter ECs0487 112 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15831518 Pathogen - hypothetical protein ECs2264 1 None None None 15831724 Common - selenophosphate synthetase ECs2470 148 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 15830837 Common - hypothetical protein ECs1583 18 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 162139793 Common - DNA-binding transcriptional activator MarA ECs2138 125 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15830445 Pathogen - hypothetical protein ECs1191 1 None None None 15832151 Common - galactitol-specific PTS system component IIA ECs2897 16 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15832463 Common - hypothetical protein ECs3209 17 None None None 15833896 Pathogen - hypothetical protein ECs4642 2 None None None 15832888 Common - hypothetical protein ECs3634 106 COG1704 LemA, Uncharacterized conserved protein Function unknown 15834123 Common metL bifunctional aspartate kinase II/homoserine dehydrogenase II ECs4869 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15829344 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase ECs0090 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 15833956 Common - acetolactate synthase 2 catalytic subunit ECs4702 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 38704080 Common - hypothetical protein ECs5495 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 15831798 Common - hypothetical protein ECs2544 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 15830794 Common - putative Dnase ECs1540 5 COG1403 McrA, Restriction endonuclease Defense mechanisms 15832069 Common - putative transport system permease protein ECs2815 84 COG2391 COG2391, Predicted transporter component General function prediction only 15831352 Common - glutamate decarboxylase isozyme ECs2098 67 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 15830436 Pathogen - hypothetical protein ECs1182 1 None None None 15829417 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase ECs0163 105 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15831604 Common - putative outer membrane protein ECs2350 22 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 15834575 Common - DNA replication protein DnaC ECs5321 41 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 15830932 Common - DNA polymerase V subunit UmuD ECs1678 55 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15831761 Common - leucine export protein LeuE ECs2507 128 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 15829696 Common - hypothetical protein ECs0442 2 None None None 15831847 Common - chemotaxis-specific methylesterase ECs2593 211 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 15833011 Common - putative oxidoreductase ECs3757 134 COG2252 COG2252, Permeases General function prediction only 15830614 Common - Iha ECs1360 130 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 15832815 Common - sorbitol-6-phosphate dehydrogenase ECs3561 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15834330 Common - aminoalkylphosphonic acid N-acetyltransferase ECs5076 50 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 15831153 Common - putative LACI-type transcriptional regulator ECs1899 126 COG1609 PurR, Transcriptional regulators Transcription 15830960 Common - hypothetical protein ECs1706 3 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 15831213 Common - hypothetical protein ECs1959 15 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 15830167 Common - hypothetical protein ECs0913 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15832547 Common - sulfate/thiosulfate transporter subunit ECs3293 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 15833066 Common - agmatinase ECs3812 152 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 15832836 Common hypA hydrogenase nickel incorporation protein ECs3582 85 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 15833199 Common - L(+)-tartrate dehydratase subunit beta ECs3945 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 15832906 Common - hypothetical protein ECs3652 29 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 15830346 Common - putative endopeptidase ECs1093 9 None None None 15833933 Common - F0F1 ATP synthase subunit C ECs4679 50 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 15833084 Common - putative deoxyribonucleotide triphosphate pyrophosphatase ECs3830 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 15832639 Common - penicillin-binding protein 1C ECs3385 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 38703973 Common - putative enzyme ECs2010 22 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15832040 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase ECs2786 119 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 15831686 Common - hypothetical protein ECs2432 13 None None None 15832318 Common - putative oxidoreductase ECs3064 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15832169 Common - putative outer membrane protein ECs2915 37 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15831818 Common - pyruvate kinase ECs2564 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 15834561 Common - type I restriction modification enzyme M subunit ECs5307 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15831703 Common - periplasmic protein ECs2449 19 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 15834039 Common - putative endonuclease ECs4785 31 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15833059 Common - putative DNA-binding transcriptional regulator ECs3805 16 COG3722 MtlR, Transcriptional regulator Transcription 15832615 Common - phosphoribosylaminoimidazole synthetase ECs3361 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 15831996 Common - hypothetical protein ECs2742 2 None None None 15830272 Common - alkanesulfonate monooxygenase ECs1018 84 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 15834340 Common - membrane channel protein component of Pn transporter ECs5086 94 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 15831793 Common - heat shock protein HtpX ECs2539 188 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15829617 Common - hypothetical protein ECs0363 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 162139710 Common - hypothetical protein ECs1676 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 38703949 Common - hypothetical protein ECs5422 2 None None None 15830603 Common - hypothetical protein ECs1349 24 None None None 15832653 Common - inositol monophosphatase ECs3399 217 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 38703923 Common - putative acyl carrier protein ECs1287 16 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15829474 Common - hypothetical protein ECs0220 21 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 15834549 Common - hypothetical protein ECs5295 67 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15831871 Common - putative integrase ECs2617 196 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15830298 Common - hypothetical protein ECs1044 59 COG1289 COG1289, Predicted membrane protein Function unknown 15833457 Common - putative ABC transporter ATP-binding protein ECs4203 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15834247 Common - hypothetical protein ECs4993 3 None None None 38704171 Common - putative GntR family regulatory protein ECs4349 136 COG2188 PhnF, Transcriptional regulators Transcription 15832733 Common - small membrane protein A ECs3479 13 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 38704198 Common tnaA tryptophanase ECs4645 44 COG3033 TnaA, Tryptophanase Amino acid transport and metabolism 15833582 Common - putative acyl carrier protein ECs4328 47 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15830522 Common - N-glycosyltransferase PgaC ECs1268 171 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15831633 Common - hypothetical protein ECs2379 5 None None None 15832201 Common - putative minor tail protein ECs2947 14 COG4672 gp18, Phage-related protein Function unknown 15832064 Common - hypothetical protein ECs2810 23 COG1289 COG1289, Predicted membrane protein Function unknown 15832526 Common - permease of transport system for 3 nucleosides ECs3272 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 38704207 Common - hypothetical protein ECs5562 2 None None None 15832490 Pathogen - putativa replication protein ECs3236 1 None None None 15830578 Common ureC urease subunit alpha ECs1324 97 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 15833649 Common - putative ARAC-type regulatory protein ECs4395 43 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15829875 Common - hypothetical protein ECs0621 4 None None None 15831733 Common - putative DEOR-type transcriptional regulator ECs2479 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15834494 Common - hypothetical protein ECs5240 78 COG0433 COG0433, Predicted ATPase General function prediction only 15832440 Common - putative S-transferase ECs3186 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15829280 Common rpsT 30S ribosomal protein S20 ECs0026 206 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 15829571 Common - hypothetical protein ECs0317 16 COG3477 COG3477, Predicted periplasmic/secreted protein Function unknown 15833485 Common aroB 3-dehydroquinate synthase ECs4231 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 15831000 Common oppD oligopeptide transporter ATP-binding component ECs1746 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15833965 Common - ATP-dependent DNA helicase Rep ECs4711 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15832316 Common - sugar efflux transport protein ECs3062 43 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832859 Common cysN sulfate adenylyltransferase subunit 1 ECs3605 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 15833589 Common - hypothetical protein ECs4335 21 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 15832963 Common - transcriptional regulator ECs3709 13 COG3710 CadC, DNA-binding winged-HTH domains Transcription 15832300 Common - putative esterase ECs3046 96 COG0627 COG0627, Predicted esterase General function prediction only 15833927 Common atpC F0F1 ATP synthase subunit epsilon ECs4673 175 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 15830777 Common - putative crossover junction endodeoxyribonuclease ECs1523 7 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 15833644 Common - stress-response and acid-resistance protein ECs4390 4 None None None 15831287 Common - hypothetical protein ECs2033 8 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 15830670 Common - curli assembly protein CsgE ECs1416 10 None None None 38703878 Pathogen - hypothetical protein ECs5380 1 None None None 15830265 Common - aromatic amino acid aminotransferase ECs1011 73 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15834057 Common - hypothetical protein ECs4803 35 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 38704084 Common - hypothetical protein ECs3304 11 None None None 15834054 Common - alpha-glucosidase ECs4800 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 15834184 Common - hypothetical protein ECs4930 59 COG0456 RimI, Acetyltransferases General function prediction only 15830979 Common - predicted invasin ECs1725 14 None None None 15831444 Common - hypothetical protein ECs2190 15 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 15832831 Common - hydrogenase 3 large subunit ECs3577 196 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 38704033 Common uvrC excinuclease ABC subunit C ECs2651 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15832861 Common - aminopeptidase in alkaline phosphatase isozyme conversion ECs3607 35 COG2234 Iap, Predicted aminopeptidases General function prediction only 15831914 Common - protein FliZ ECs2660 9 None None None 15833039 Common - ribose-5-phosphate isomerase A ECs3785 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 15833187 Common - hypothetical protein ECs3933 45 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 15833980 Common - 4-alpha-L-fucosyltransferase ECs4726 17 None None None 15829811 Common - multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 ECs0558 98 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 15830147 Common - hypothetical protein ECs0893 47 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15830181 Common - hypothetical protein ECs0927 57 COG2985 COG2985, Predicted permease General function prediction only 15830764 Common - putative replication protein ECs1510 5 None None None 15834345 Common - hypothetical protein ECs5091 12 COG1160 COG1160, Predicted GTPases General function prediction only 15834440 Common - D-alanine/D-serine/glycine permease ECs5186 172 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15831537 Pathogen - hypothetical protein ECs2283 1 None None None 15834331 Common - ribose 1,5-bisphosphokinase ECs5077 74 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 15832606 Common - putative protein processing element ECs3352 13 None None None 15830586 Pathogen - putative colicin immunity protein ECs1332 2 None None None 15830221 Common clpS ATP-dependent Clp protease adaptor protein ClpS ECs0967 122 COG2127 COG2127, Uncharacterized conserved protein Function unknown 162139723 Common hslO Hsp33-like chaperonin ECs4243 138 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 15831844 Common flhB flagellar biosynthesis protein FlhB ECs2590 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 15831609 Common - superoxide dismutase ECs2355 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 15834257 Common - sorbitol-6-phosphate 2-dehydrogenase ECs5003 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15829466 Pathogen - hypothetical protein ECs0212 1 None None None 15830467 Common - putative endolysin ECs1213 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 38704017 Common - hypothetical protein ECs2489 59 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 15831384 Common - hypothetical protein ECs2130 15 None None None 15830256 Common - hypothetical protein ECs1002 10 None None None 15829535 Common - hypothetical protein ECs0281 9 None None None 15831648 Common - putative oxidase ECs2394 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15829297 Common - L-carnitine/gamma-butyrobetaine antiporter ECs0043 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 15831390 Common - multiple drug resistance protein MarC ECs2136 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 15831684 Common - hypothetical protein ECs2430 7 None None None 15833074 Common - hypothetical protein ECs3820 26 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 15831414 Common - putative outer host membrane protein precursor ECs2160 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15832089 Common - phosphomannomutase ECs2835 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15831399 Common - hypothetical protein ECs2145 15 COG3111 COG3111, Uncharacterized conserved protein Function unknown 15832763 Common - hypothetical protein ECs3509 12 None None None 15829858 Pathogen - hypothetical protein ECs0604 1 None None None 15834566 Common - hypothetical protein ECs5312 27 COG2879 COG2879, Uncharacterized small protein Function unknown 15833387 Common fis DNA-binding protein Fis ECs4133 97 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 15834378 Common groEL chaperonin GroEL ECs5124 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15829716 Common - hypothetical protein ECs0462 17 COG3668 ParE, Plasmid stabilization system protein General function prediction only 15833334 Common - putative ABC transporter ATP-binding protein YhbG ECs4080 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 15833371 Common - suppresses inhibitory activity of CsrA ECs4117 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15831421 Pathogen - putative minor tail protein ECs2167 3 None None None 15833524 Common - hypothetical membrane protein ECs4270 2 None None None 15829851 Common - transcriptional regulator FimZ ECs0597 195 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15832235 Common - putative DNA methylase ECs2981 10 None None None 15830535 Pathogen - hypothetical protein ECs1281 1 None None None 15833427 Common rplE 50S ribosomal protein L5 ECs4173 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 15829574 Common - putative receptor ECs0320 4 None None None 15829904 Common - ribonuclease I ECs0650 32 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 15830536 Common - hemagglutinin/hemolysin-related protein ECs1282 97 None None None 15833836 Common - EscS ECs4582 45 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 15830023 Common - cytochrome d terminal oxidase polypeptide subunit II ECs0769 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 15830515 Common - major sodium/proline symporter ECs1261 177 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 15833386 Common - tRNA-dihydrouridine synthase B ECs4132 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15832296 Common - galactose-binding transport protein ECs3042 91 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15829559 Common - hypothetical protein ECs0305 103 COG0583 LysR, Transcriptional regulator Transcription 15830425 Common - hypothetical protein ECs1171 2 None None None 15830559 Common - hypothetical protein ECs1305 129 COG4951 COG4951, Uncharacterized protein conserved in bacteria Function unknown 15830368 Common - putative tail length tape measure protein ECs1114 20 COG5281 COG5281, Phage-related minor tail protein Function unknown 15829915 Common - palmitoyl transferase for Lipid A ECs0661 14 None None None 15829429 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase ECs0175 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 162139736 Common - acetylglutamate kinase ECs4888 208 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 15829407 Common mrcB penicillin-binding protein 1b ECs0153 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 15830379 Pathogen - EspF-like protein ECs1126 1 None None None 15831417 Common - putative tail assembly protein ECs2163 14 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15829644 Common - cytosine deaminase ECs0390 71 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15833678 Common - dipeptide transport protein ECs4424 212 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15834449 Common - hypothetical protein ECs5195 15 None None None 15829639 Common prpB 2-methylisocitrate lyase ECs0385 135 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 15829728 Common - 1-deoxy-D-xylulose-5-phosphate synthase ECs0474 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 15829357 Common - nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP ECs0103 158 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15832782 Common - hypothetical protein ECs3528 87 COG0640 ArsR, Predicted transcriptional regulators Transcription 15831573 Common - mannose-6-phosphate isomerase ECs2319 41 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 15832856 Common ftsB cell divison protein FtsB ECs3602 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 15832978 Common - EpaQ ECs3724 54 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 15829594 Common - hypothetical protein ECs0339 1 None None None 162139725 Common - isovaleryl CoA dehydrogenase ECs5163 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 15830946 Common - hypothetical protein ECs1692 61 COG2261 COG2261, Predicted membrane protein Function unknown 38704122 Common - hypothetical protein ECs3706 1 None None None 15834194 Pathogen - hypothetical protein ECs4940 1 None None None 15834287 Common - quinone oxidoreductase, NADPH-dependent ECs5033 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 15830873 Common - endodeoxyribonuclease RUS ECs1619 7 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 15833635 Pathogen - hypothetical protein ECs4381 2 None None None 162139742 Common - putative oxidoreductase ECs4630 39 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15833622 Common - inner membrane transporter YhiP ECs4368 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 15834280 Common - LexA repressor ECs5026 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15830864 Common - excisionase ECs1610 2 None None None 15833997 Common uvrD DNA-dependent helicase II ECs4743 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15831526 Common - hypothetical protein ECs2272 4 None None None 15830736 Common - hypothetical protein ECs1482 10 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 38704254 Pathogen - hypothetical protein ECs5592 1 None None None 15833030 Common gcvT glycine cleavage system aminomethyltransferase T ECs3776 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 15830841 Common - putative single stranded DNA-binding protein ECs1587 48 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15829495 Common - H repeat-associated protein ECs0241 35 COG5433 COG5433, Transposase DNA replication, recombination, and repair 162139809 Common fbpC ferric transporter ATP-binding subunit ECs0413 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15834070 Common - hypothetical protein ECs4816 10 None None None 15830353 Pathogen - hypothetical protein ECs1099 1 None None None 15831716 Common - putative ATP-binding component of a transport system ECs2462 249 COG4136 COG4136, ABC-type uncharacterized transport system, ATPase component General function prediction only 15833476 Common frlB fructoselysine-6-P-deglycase ECs4222 224 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 15832521 Common - putative PTS system enzyme IIB component ECs3267 66 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 15831498 Common - hypothetical protein ECs2244 2 None None None 15833569 Common - hypothetical protein ECs4315 15 COG3776 COG3776, Predicted membrane protein Function unknown 15834306 Common nrfA cytochrome c nitrite reductase ECs5052 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 38704182 Common - aldehyde dehydrogenase B ECs4464 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15829847 Common - putative chaperone ECs0593 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15829364 Common - type IV pilin biogenesis protein ECs0110 144 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 15829518 Common - PepD ECs0264 60 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 15832936 Common - hypothetical protein ECs3682 12 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 15829784 Common - inosine-guanosine kinase ECs0530 56 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15834405 Common - FtsH protease regulator HflC ECs5151 153 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 38703933 Common - purine nucleoside phosphoramidase ECs1481 224 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15833995 Common xerC site-specific tyrosine recombinase XerC ECs4741 226 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 15830664 Common - putative dehydrogenase ECs1410 228 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15831567 Common - hypothetical protein ECs2313 14 COG3136 GlpM, Uncharacterized membrane protein required for alginate biosynthesis General function prediction only 15832125 Common - putative assembly protein ECs2871 44 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 15829561 Pathogen - hypothetical protein ECs0307 1 None None None 15832126 Common dcd deoxycytidine triphosphate deaminase ECs2872 153 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 15832364 Common - hypothetical protein ECs3110 7 COG5445 COG5445, Predicted secreted protein Function unknown 15834610 Common - DNA-binding response regulator CreB ECs5356 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15833517 Common - RNA 3'-terminal-phosphate cyclase ECs4263 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 15834532 Common - FimG ECs5278 12 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832661 Common - 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase ECs3407 230 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15830485 Pathogen - putative outer membrane protein ECs1231 1 None None None 15834074 Common - formate dehydrogenase-O major subunit ECs4820 185 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15830574 Pathogen - hypothetical protein ECs1320 1 None None None 15834003 Common - hypothetical protein ECs4749 119 COG2962 RarD, Predicted permeases General function prediction only 15831971 Common - putative tail fiber protein ECs2717 4 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15830755 Common - putative integrase ECs1501 19 None None None 15829630 Common - putative ATP binding protein of a transporter ECs0376 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15831476 Common - hypothetical protein ECs2222 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834397 Common - hypothetical protein ECs5142 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 15832499 Common - D-serine dehydratase ECs3245 39 COG3048 DsdA, D-serine dehydratase Amino acid transport and metabolism 15830483 Pathogen - hypothetical protein ECs1229 1 None None None 15833216 Common - predicted glycosyl hydrolase ECs3962 20 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 38703940 Common - hypothetical protein ECs1573 58 COG2850 COG2850, Uncharacterized conserved protein Function unknown 15833408 Common - 16S rRNA methyltransferase B ECs4154 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 15829501 Common - vertebrate C-lysozyme inhibitor ECs0247 7 None None None 15830094 Common - putative tail assembly protein ECs0840 14 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15833366 Common - hypothetical protein ECs4112 9 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 38703843 Common - acetolactate synthase 3 catalytic subunit ECs0081 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15832605 Common - hydrogenase 4 Fe-S subunit ECs3351 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 15830846 Common - putative head portal protein ECs1592 67 COG4695 COG4695, Phage-related protein Function unknown 15834105 Common glpK glycerol kinase ECs4851 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 162139769 Common - hypothetical protein ECs3198 21 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 15829289 Common - carbamoyl phosphate synthase small subunit ECs0035 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 15832226 Common - hypothetical protein ECs2972 3 None None None 15830394 Common - hypothetical protein ECs1140 23 None None None 15830183 Common grxA glutaredoxin 1 ECs0929 48 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 15831036 Common - putative holin protein ECs1782 5 None None None 15830011 Common - putative fumarate hydratase ECs0757 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15829679 Common - putative DNA-binding transcriptional regulator ECs0425 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15832941 Common - dinucleoside polyphosphate hydrolase ECs3687 115 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15833025 Common - putative oxidoreductase ECs3771 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 15833447 Common rpsL 30S ribosomal protein S12 ECs4193 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 15834313 Common gltP glutamate/aspartate:proton symporter ECs5059 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 15834591 Common - putative activating enzyme ECs5337 71 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15834458 Common - inorganic pyrophosphatase ECs5204 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 15833753 Common - ADP-heptose:LPS heptosyl transferase I ECs4499 88 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15829622 Common - hypothetical protein ECs0368 5 None None None 15832031 Common - hypothetical protein ECs2777 13 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15830193 Common rumB 23S rRNA metyluridine methyltransferase ECs0939 184 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 38704002 Common - hypothetical protein ECs2348 11 COG3895 COG3895, Predicted periplasmic protein General function prediction only 15830327 Common - hypothetical protein ECs1073 9 None None None 15831886 Pathogen - hypothetical protein ECs2632 1 None None None 15833278 Common - putative transposase ECs4024 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833954 Common - putative ATP-dependent protease ECs4700 201 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 15831106 Common - hypothetical protein ECs1852 21 COG3771 COG3771, Predicted membrane protein Function unknown 15830312 Common - hypothetical protein ECs1058 4 None None None 15834212 Pathogen - hypothetical protein ECs4958 1 None None None 15829528 Common - cI ECs0274 28 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15834474 Common - hypothetical protein ECs5220 183 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15833655 Common - putative transcriptional regulator LYSR-type ECs4401 183 COG0583 LysR, Transcriptional regulator Transcription 15831020 Common - DNA-binding transcriptional regulator DicC ECs1766 7 None None None 15833733 Common - hypothetical protein ECs4479 3 None None None 15833638 Common - ShuX-like protein ECs4384 18 COG3721 HugX, Putative heme iron utilization protein Inorganic ion transport and metabolism 15831801 Common - hypothetical protein ECs2547 8 None None None 15832588 Common - succinyl-diaminopimelate desuccinylase ECs3334 214 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15830797 Common - putative major head protein/prohead proteinase ECs1543 23 COG3740 COG3740, Phage head maturation protease General function prediction only 15830746 Common - transcription-repair coupling factor ECs1492 233 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 15831754 Common - putative amino acid/amine transport protein ECs2500 78 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 15831089 Common - bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase ECs1835 230 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 38703898 Common - putative transferase ECs0918 95 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15831029 Pathogen - hypothetical protein ECs1775 5 None None None 38704262 Common - putative GTP-binding protein YjiA ECs5311 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 15831062 Common - putative tail fiber protein ECs1808 3 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15834178 Common - hypothetical protein ECs4924 10 None None None 15831194 Common - hypothetical protein ECs1940 1 None None None 15832115 Common - putative colanic acid polymerase ECs2861 6 None None None 15830292 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase ECs1038 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 15830076 Pathogen - hypothetical protein ECs0822 2 None None None 15832807 Common - carbon storage regulator ECs3553 81 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 38703871 Common - hypothetical protein ECs0511 10 None None None 15829807 Common - putative ABC transporter ATP-binding protein YbbL ECs0553 249 COG4619 COG4619, ABC-type uncharacterized transport system, ATPase component General function prediction only 15834021 Common - sec-independent translocase ECs4767 38 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 15830724 Common - acyl carrier protein S-malonyltransferase ECs1470 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 38704189 Pathogen - hypothetical protein ECs5537 2 None None None 15829932 Common holA DNA polymerase III subunit delta ECs0678 69 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 15829461 Common - predicted membrane-bound lytic murein transglycosylase D ECs0207 152 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15834536 Common - D-mannonate oxidoreductase ECs5282 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15833419 Common secY preprotein translocase subunit SecY ECs4165 225 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 15831297 Common - putative transcriptional regulator ECs2043 231 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 15830144 Common - DNA starvation/stationary phase protection protein Dps ECs0890 118 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 15831279 Common - hypothetical protein ECs2025 2 None None None 15829584 Common - hypothetical protein ECs0330 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834421 Common - putative DEOR-type transcriptional regulator ECs5167 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15832325 Common - putative transport system permease protein ECs3071 218 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 15833289 Common - hypothetical protein ECs4035 20 COG3787 COG3787, Uncharacterized protein conserved in bacteria Function unknown 15833268 Common - N-acetyl-galactosamine/galactosamine PTS system enzyme IIA component ECs4014 80 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 15832025 Common - hypothetical protein ECs2771 8 None None None 15833313 Common - RNA-binding protein YhbY ECs4059 98 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 15832042 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase ECs2788 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 38704159 Common - bacterioferritin-associated ferredoxin ECs5531 25 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 15831898 Common - putative tail tube protein ECs2644 24 COG3498 COG3498, Phage tail tube protein FII General function prediction only 15831350 Common - hypothetical protein ECs2096 40 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 38704046 Common - putative transport protein ECs2868 219 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15830490 Common - putative outer membrane precursor ECs1236 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15831290 Common - hypothetical protein ECs2036 12 None None None 15832684 Common - pyridoxal phosphate biosynthetic protein PdxJ ECs3430 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 15832557 Common - hypothetical protein ECs3303 11 None None None 15833702 Common - xylose isomerase ECs4448 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 15830768 Pathogen - hypothetical protein ECs1514 2 None None None 15829422 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase ECs0168 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 15832843 Common - DNA mismatch repair protein ECs3589 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15833467 Common - hypothetical protein ECs4213 6 None None None 15833301 Common truB tRNA pseudouridine synthase B ECs4047 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 15833715 Common - putative transcriptional regulator LYSR-type ECs4461 134 COG0583 LysR, Transcriptional regulator Transcription 15831115 Common - enoyl-(acyl carrier protein) reductase ECs1861 231 COG0623 FabI, Enoyl- acyl-carrier-protein 15832877 Common - putative anti-terminator regulatory protein ECs3623 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 15830372 Common - putative tail assembly protein ECs1118 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 15830497 Pathogen - hypothetical protein ECs1243 1 None None None 15831206 Pathogen - hypothetical protein ECs1952 2 None None None 15833280 Common - disrupted fimbrial protein ECs4026 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832348 Common napG quinol dehydrogenase periplasmic component ECs3094 65 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15830782 Pathogen - hypothetical protein ECs1528 1 None None None 15831823 Common znuB high-affinity zinc transporter membrane component ECs2569 185 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15829776 Common - adenine phosphoribosyltransferase ECs0522 189 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15831238 Common - putative minor tail protein ECs1984 7 COG4718 COG4718, Phage-related protein Function unknown 15832844 Common - serine/threonine-specific protein phosphatase 2 ECs3590 71 None None None 15830082 Common - hypothetical protein ECs0828 9 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 38703851 Pathogen - hypothetical protein ECs5374 1 None None None 38704005 Common - putative acyl-CoA dehydrogenase ECs2402 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 15831136 Common pspB phage shock protein B ECs1882 23 None None None 15832990 Common - hypothetical protein ECs3736 9 None None None 15831673 Common ihfA integration host factor subunit alpha ECs2419 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 162139787 Common - nicotinamidase/pyrazinamidase ECs2475 129 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 38703944 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase ECs1605 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 15831072 Common - hypothetical protein ECs1818 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829267 Common - hypothetical protein ECs0013 4 None None None 15834523 Common - hypothetical protein ECs5269 19 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 15831333 Common - nitrate-inducible formate dehydrogenase-N iron-sulfur beta subunit ECs2079 161 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15833796 Common - hypothetical protein ECs4542 8 None None None 15831835 Common - hypothetical protein ECs2581 54 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 15834356 Common - melibiose:sodium symporter ECs5102 76 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15831666 Common - hypothetical protein ECs2412 6 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 15830596 Pathogen - hypothetical protein ECs1342 3 None None None 15831954 Common - hypothetical protein ECs2700 62 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 15832722 Common - predicted outer membrane lipoprotein ECs3468 144 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15830069 Common - anti-termination protein ECs0815 6 None None None 15832099 Common - putative glycosyl transferase ECs2845 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15834148 Common - DNA-binding transcriptional repressor FabR ECs4894 41 COG1309 AcrR, Transcriptional regulator Transcription 38704105 Common - hypothetical protein ECs3426 12 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15831828 Common - hypothetical protein ECs2574 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 15830383 Common - hydrogenase 1 large subunit ECs1129 107 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 15833229 Common - transport protein of hexuronates ECs3975 112 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15834322 Common - putative sugar kinase ECs5068 86 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15833828 Pathogen - SepD ECs4574 1 None None None 15830964 Common - predicted inner membrane protein ECs1710 10 None None None 15832179 Common - putative regulator ECs2925 11 None None None 15832959 Common - hypothetical protein ECs3705 4 None None None 15834362 Common - hypothetical protein ECs5108 19 COG3592 COG3592, Uncharacterized conserved protein Function unknown 15829384 Common - carbonic anhydrase ECs0130 117 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 15832517 Common - putative PTS system enzyme IIA component ECs3263 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 15833834 Common - secretion system apparatus protein SsaU ECs4580 129 COG4792 EscU, Type III secretory pathway, component EscU Intracellular trafficking and secretion 15832958 Common - putative sensory transducer ECs3704 12 COG3710 CadC, DNA-binding winged-HTH domains Transcription 15831637 Common - pyruvate kinase ECs2383 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 15833616 Common - hypothetical protein ECs4362 2 None None None 38703910 Common - hypothetical protein ECs1082 6 None None None 15829818 Common - tRNA 2-selenouridine synthase ECs0564 65 COG2603 COG2603, Predicted ATPase General function prediction only 15831359 Pathogen - hypothetical protein ECs2105 2 None None None 15831164 Common - putative transcriptional regulator LYSR-type ECs1910 134 COG0583 LysR, Transcriptional regulator Transcription 15833236 Common - hypothetical protein ECs3982 9 None None None 15833873 Common - putative sulfatase ECs4619 94 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 15833354 Common - putative cryptic C4-dicarboxylate transporter DcuD ECs4100 25 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 15834581 Common - ferric iron reductase involved in ferric hydroximate transport ECs5327 17 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 15831270 Pathogen - hypothetical protein ECs2016 1 None None None 15831367 Common - putative type 1 fimbrial protein precursor ECs2113 21 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15829826 Common - allantoin permease ECs0572 50 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 15832519 Common - putative peptidase ECs3265 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15832281 Common - salicylate hydroxylase ECs3027 74 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 15832288 Common - predicted inner membrane protein ECs3034 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 15834079 Common - putative PTS transporter components IIBC ECs4825 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 38704050 Common - fructose-bisphosphate aldolase ECs2900 57 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 15834163 Common rplL 50S ribosomal protein L7/L12 ECs4909 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 15833831 Pathogen - hypothetical protein ECs4577 2 None None None 15833722 Common - selenocysteine synthase ECs4468 73 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 15830350 Common - putative endolysin ECs1096 26 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15832510 Common - hypothetical protein ECs3256 2 None None None 15831031 Common - endonuclease ECs1777 7 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 38704176 Common bcsA cellulose synthase catalytic subunit ECs4413 122 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15834429 Common - hypothetical protein ECs5175 8 None None None 15830074 Common - putative endopeptidase ECs0820 8 None None None 15833737 Common lldD L-lactate dehydrogenase ECs4483 133 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 15830464 Pathogen - hypothetical protein ECs1210 1 None None None 15831275 Common - aldehyde dehydrogenase A ECs2021 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15831527 Pathogen - hypothetical protein ECs2273 3 None None None 15833725 Common - hypothetical protein ECs4471 4 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15831658 Common - putative electron transfer flavoprotein YdiQ ECs2404 151 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 15834577 Common - hypothetical protein ECs5323 21 COG3610 COG3610, Uncharacterized conserved protein Function unknown 15832957 Common - hypothetical protein ECs3703 5 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 15829505 Common - hypothetical protein ECs0251 53 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 15830344 Common - putative transposase ECs1090 114 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834389 Common - fumarate reductase flavoprotein subunit ECs5135 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 15830718 Common - 23S rRNA pseudouridylate synthase C ECs1464 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15831649 Common - predicted inner membrane protein ECs2395 88 COG0628 PerM, Predicted permease General function prediction only 15834377 Common groES co-chaperonin GroES ECs5123 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 15831832 Common - hypothetical protein ECs2578 85 COG1801 COG1801, Uncharacterized conserved protein Function unknown 15832469 Common - hypothetical protein ECs3214 70 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 15834125 Common - hydroperoxidase HPI(I) ECs4871 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 15831340 Common - osmotically inducible protein ECs2086 91 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15830295 Common - outer membrane protein A ECs1041 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15831138 Common - peripheral inner membrane phage-shock protein ECs1884 8 None None None 15834414 Common - hypothetical protein ECs5160 29 COG3766 COG3766, Predicted membrane protein Function unknown 15829537 Common - putative tail fiber protein ECs0283 5 None None None 15831200 Pathogen - hypothetical protein ECs1946 4 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 15830870 Common - hypothetical protein ECs1616 5 None None None 15830012 Common - putative transport protein ECs0758 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 15832724 Common trmD tRNA (guanine-N(1)-)-methyltransferase ECs3470 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 15829514 Common - putative toxin YafO ECs0260 6 None None None 15829265 Common - hypothetical protein ECs0012 8 COG4735 COG4735, Uncharacterized protein conserved in bacteria Function unknown 15833792 Common - hypothetical protein ECs4538 10 None None None 15833227 Common - altronate hydrolase ECs3973 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 15829664 Common - putative esterase ECs0410 104 COG0627 COG0627, Predicted esterase General function prediction only 15831978 Common - putative minor tail protein ECs2724 13 COG4718 COG4718, Phage-related protein Function unknown 15830839 Pathogen - hypothetical protein ECs1585 1 None None None 15830398 Common - cold shock-like protein ECs1144 43 COG1278 CspC, Cold shock proteins Transcription 15833294 Common - hypothetical protein ECs4040 49 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15829520 Common frsA fermentation/respiration switch protein ECs0266 26 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 15829766 Common - maltose O-acetyltransferase ECs0512 120 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 38704042 Common - imidazole glycerol-phosphate dehydratase/histidinol phosphatase ECs2823 218 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 15833279 Common - putative transposase ECs4025 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 38704195 Common - PTS system arbutin-like IIC component ECs4623 52 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15833888 Common gyrB DNA gyrase subunit B ECs4634 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15831338 Common rpsV 30S ribosomal subunit S22 ECs2084 5 None None None 15831131 Common - gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase ECs1877 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15832360 Common - DNA-binding response regulator in two-component regulatory system with RcsC and YojN ECs3106 170 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15829588 Pathogen - hypothetical protein ECs0334 1 None None None 15832356 Common - O6-methylguanine-DNA methyltransferase ECs3102 189 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 15833745 Common - hypothetical protein ECs4491 201 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 15830787 Common - antirepressor protein ECs1533 8 None None None 38704180 Common - hypothetical protein ECs5536 6 None None None 38704103 Common - hypothetical protein ECs5498 7 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 38704228 Common pspG phage shock protein G ECs5032 10 None None None 15831669 Common - lipoprotein ECs2415 139 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15832897 Common - antitoxin MazE ECs3643 28 COG2336 MazE, Growth regulator Signal transduction mechanisms 15832034 Common - hypothetical protein ECs2780 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 15829509 Common - hypothetical protein ECs0255 28 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831735 Common - putative kinase ECs2481 191 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15830090 Pathogen - putative minor tail protein ECs0836 3 None None None 15832905 Common - tRNA pseudouridine synthase C ECs3651 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15829990 Common - putative carboxylase ECs0736 101 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 15829567 Common - hypothetical protein ECs0313 75 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 15833224 Common - putative transport protein ECs3970 103 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15833658 Common - hypothetical protein ECs4404 34 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 15829370 Common - aromatic amino acid transporter ECs0116 171 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15831157 Common tpx thiol peroxidase ECs1903 111 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15830703 Common - anti-sigma28 factor FlgM ECs1449 12 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 15833442 Common - HopD ECs4188 117 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 38704141 Common - hypothetical protein ECs3993 183 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 38704242 Common - hypothetical protein ECs5165 9 None None None 15832596 Common bcp thioredoxin-dependent thiol peroxidase ECs3342 216 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15834396 Common - hypothetical protein ECs5143 137 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 15833415 Common rpsD 30S ribosomal protein S4 ECs4161 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15830847 Common - putative head-tail adaptor ECs1593 8 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 15834183 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ECs4929 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 15834428 Common sgaE L-ribulose-5-phosphate 4-epimerase ECs5174 138 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 15831052 Common - hypothetical protein ECs1798 5 None None None 15832991 Common - hypothetical protein ECs3737 2 None None None 15830620 Pathogen - hypothetical protein ECs1366 2 None None None 15832116 Common - predicted glycosyl transferase ECs2862 23 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15834572 Common - putative oxidoreductase ECs5318 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15834515 Common - putative ATP-dependent helicase ECs5261 135 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 15833734 Common - hypothetical protein ECs4480 84 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 162139815 Common - glutamyl-Q tRNA(Asp) synthetase ECs0148 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15831017 Pathogen - hypothetical protein ECs1763 1 None None None 15832920 Common - hypothetical protein ECs3666 45 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 15832708 Common - alpha-ketoglutarate transporter ECs3454 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832200 Common - putative tail assembly protein ECs2946 14 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15833360 Common - cytochrome d ubiquinol oxidase subunit III ECs4106 22 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 15834028 Common fadB multifunctional fatty acid oxidation complex subunit alpha ECs4774 191 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 15831147 Common - hypothetical protein ECs1893 59 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 15831611 Common - hypothetical protein ECs2358 26 COG3313 COG3313, Predicted Fe-S protein General function prediction only 15831632 Common - putative oxidoreductase Fe-S subunit ECs2378 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15832916 Common fucI L-fucose isomerase ECs3662 19 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 15829982 Common - hypothetical protein ECs0728 11 None None None 38703874 Common - hypothetical protein ECs0563 16 None None None 15829913 Common - DNA-binding response regulator in two-component regulatory system with citA ECs0659 163 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 15833513 Common - maltodextrin phosphorylase ECs4259 128 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 15833938 Common - flavodoxin ECs4684 79 COG0716 FldA, Flavodoxins Energy production and conversion 15832110 Common - GDP-mannose mannosyl hydrolase ECs2856 24 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15830548 Common - hypothetical protein ECs1294 126 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15832229 Common - antitermination protein ECs2975 6 None None None 15831431 Common - putative portal protein ECs2177 32 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 38704066 Common - hypothetical protein ECs3138 13 None None None 15829437 Common - UDP-N-acetylglucosamine acyltransferase ECs0183 153 COG1043 LpxA, Acyl- acyl carrier protein 15830675 Common - CsgC ECs1421 5 None None None 15834611 Common - sensory histidine kinase CreC ECs5357 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15829935 Common - hypothetical protein ECs0681 22 None None None 15834368 Common - predicted lysine/cadaverine transporter ECs5114 167 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15830319 Common - hypothetical protein ECs1065 4 None None None 15829521 Common - DNA-binding transcriptional regulator Crl ECs0267 13 None None None 15832029 Common - hypothetical protein ECs2775 95 None None None 15832070 Common - putative amino acid/amine transport protein ECs2816 161 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15834195 Common - putative L-sorbose 1-phosphate dehydrogenase ECs4941 51 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15832124 Common - hypothetical protein ECs2870 23 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 15832121 Common - putative polysaccharide export protein ECs2867 124 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 15833691 Common - predicted outer membrane lipoprotein ECs4437 167 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15829382 Common - glucose dehydrogenase ECs0128 60 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 15833050 Common - fructose-bisphosphate aldolase ECs3796 174 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15830830 Pathogen - hypothetical protein ECs1576 2 None None None 15832152 Common - putative tagatose 6-phosphate kinase 1 ECs2898 34 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 15829977 Common - sensor protein KdpD ECs0723 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 15830447 Pathogen - hypothetical protein ECs1193 1 None None None 15832972 Common - EprI ECs3718 9 None None None 38704008 Common - 6-phosphofructokinase 2 ECs2429 145 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 15833799 Common - hypothetical protein ECs4545 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831234 Common - major tail protein ECs1980 6 None None None 15829805 Common - hypothetical protein ECs0551 41 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15831245 Common - putative outer membrane protein ECs1991 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15829629 Common - putative ATP binding protein of a transporter ECs0375 229 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15831387 Common - putative transcriptional regulator LYSR-type ECs2133 171 COG0583 LysR, Transcriptional regulator Transcription 15832585 Common - nitrate/nitrite sensor protein NarQ ECs3331 121 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 15833418 Common rpmJ 50S ribosomal protein L36 ECs4164 134 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 162139764 Common - putative DNA-binding transcriptional regulator ECs3427 128 COG1737 RpiR, Transcriptional regulators Transcription 15833271 Common kbaY tagatose-bisphosphate aldolase ECs4017 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15830086 Pathogen - putative minor tail protein ECs0832 4 None None None 15831509 Common - hypothetical protein ECs2255 1 None None None 15832147 Common - split galactitol utilization operon repressor ECs2893 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15831180 Common zntB zinc transporter ECs1926 98 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 15831756 Common - hypothetical protein ECs2502 17 COG3042 Hlx, Putative hemolysin General function prediction only 38704249 Common - hypothetical protein ECs5229 30 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 15829426 Common tsf elongation factor Ts ECs0172 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 15834498 Common - putative transposase ECs5244 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831374 Common - putative ATP-binding component of a transport system ECs2120 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15833439 Common rplC 50S ribosomal protein L3 ECs4185 231 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 38704070 Common - menaquinone-specific isochorismate synthase ECs3153 221 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15833823 Common - T ECs4569 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 15831038 Common - putative endolysin ECs1784 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15831149 Common - hypothetical protein ECs1895 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 15833817 Pathogen - hypothetical protein ECs4563 1 None None None 15832995 Common - xanthine dehydrogenase subunit XdhC ECs3741 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 15831433 Common - putative terminase large subunit ECs2179 36 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 38704062 Common - hypothetical protein ECs3069 172 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15829750 Common - hypothetical protein ECs0496 79 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 15831269 Common - ATP-dependent RNA helicase HrpA ECs2015 133 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 15832784 Common - DNA binding protein, nucleoid-associated ECs3530 32 COG2916 Hns, DNA-binding protein H-NS General function prediction only 15833248 Common - putative formate acetyltransferase 3 ECs3994 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 15833754 Common - lipid A-core:surface polymer ligase ECs4500 12 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 15833598 Common - nickel transporter permease NikB ECs4344 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15831319 Common - hypothetical protein ECs2065 39 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 15829337 Pathogen - fruR leader peptide ECs0083 2 None None None 15832675 Common - hypothetical protein ECs3421 10 None None None 15830427 Pathogen - hypothetical protein ECs1173 2 None None None 15834601 Common - DNA repair protein RadA ECs5347 217 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 15830476 Common - hypothetical protein ECs1222 7 None None None 15833562 Common - hypothetical protein ECs4308 33 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 15830866 Common - replication protein P ECs1612 11 None None None 38704088 Common - hypothetical protein ECs3324 20 COG4810 EutS, Ethanolamine utilization protein Amino acid transport and metabolism 15832522 Common glk glucokinase ECs3268 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 15831173 Common - putative transposase ECs1919 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829460 Common - putative biotin synthesis protein ECs0206 212 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15831559 Common - multidrug efflux system protein MdtI ECs2305 108 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 38703937 Pathogen - hypothetical protein ECs5417 1 None None None 15830558 Common - hypothetical protein ECs1304 8 None None None 15830914 Common - hypothetical protein ECs1660 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831597 Common tppB putative tripeptide transporter permease ECs2343 86 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 15831449 Common - hypothetical protein ECs2195 6 None None None 15830666 Common - putative oxidoreductase component ECs1412 20 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 15830330 Pathogen - hypothetical protein ECs1076 3 None None None 15831741 Common - methionine sulfoxide reductase B ECs2487 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15829711 Common tgt queuine tRNA-ribosyltransferase ECs0457 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 15829722 Common ribH riboflavin synthase subunit beta ECs0468 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 15833591 Common - hypothetical lipoprotein ECs4337 12 None None None 15829621 Common - putative transcription factor ECs0367 85 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 15829854 Common - bacteriophage N4 receptor, outer membrane subunit ECs0600 9 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15833982 Common - putative UDP-N-acetyl-D-mannosaminuronic acid transferase ECs4728 108 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 15832238 Pathogen - hypothetical protein ECs2984 3 None None None 15834291 Common aphA acid phosphatase/phosphotransferase ECs5037 12 COG3700 AphA, Acid phosphatase (class B) General function prediction only 15834303 Common actP acetate permease ECs5049 161 COG4147 DhlC, Predicted symporter General function prediction only 15832061 Common - hypothetical protein ECs2807 2 None None None 15834484 Common - hypothetical protein ECs5230 2 None None None 15831521 Common - putative antitermination protein ECs2267 6 None None None 15831535 Common - hypothetical protein ECs2281 26 COG3668 ParE, Plasmid stabilization system protein General function prediction only 15832662 Common - phenylpropionate dioxygenase, ferredoxin reductase subunit ECs3408 207 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 38704247 Common - cytochrome b(562) ECs5213 11 COG3783 CybC, Soluble cytochrome b562 Energy production and conversion 15833483 Common - DNA adenine methylase ECs4229 98 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 15833346 Common gltD glutamate synthase subunit beta ECs4092 211 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 15829395 Common - putative fimbrial protein ECs0141 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 38703886 Common - hypothetical protein ECs0675 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 15830364 Pathogen - putative major head protein ECs1110 4 None None None 15833077 Common - glutathione synthetase ECs3823 124 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 15832233 Pathogen - hypothetical protein ECs2979 1 None None None 15830220 Common - stationary phase/starvation inducible regulatory protein CspD ECs0966 176 COG1278 CspC, Cold shock proteins Transcription 15833139 Common - aldo-keto reductase ECs3885 197 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 15834051 Common - predicted outer membrane porin L ECs4797 5 None None None 15833714 Common - putative outer membrane protein ECs4460 34 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 38704151 Common - putative sialic acid transporter ECs4097 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15831166 Common - hypothetical protein ECs1912 176 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15830844 Common - putative major head protein ECs1590 51 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 15829457 Common dkgB 2,5-diketo-D-gluconate reductase B ECs0203 187 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 15833204 Common - RNA polymerase sigma factor RpoD ECs3950 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15833432 Common rplP 50S ribosomal protein L16 ECs4178 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 15829645 Common - DNA-binding transcriptional regulator CynR ECs0391 190 COG0583 LysR, Transcriptional regulator Transcription 15829438 Common lpxB lipid-A-disaccharide synthase ECs0184 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 15831424 Pathogen - putative minor tail protein ECs2170 3 None None None 15829558 Common - hypothetical protein ECs0304 2 None None None 38704003 Common - hypothetical protein ECs2353 169 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15831294 Common - hypothetical protein ECs2040 4 None None None 15829759 Common - ammonium transporter ECs0505 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 15830022 Common - cytochrome d terminal oxidase polypeptide subunit I ECs0768 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 15833903 Common - hypothetical protein ECs4649 8 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 15830100 Pathogen - hypothetical protein ECs0846 2 None None None 15830029 Common tolB translocation protein TolB ECs0775 157 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 15834284 Common - hypothetical protein ECs5030 2 None None None 15834447 Common - hypothetical protein ECs5193 2 None None None 162139713 Common - hypothetical protein ECs2077 45 None None None 15831453 Common - hypothetical protein ECs2199 3 None None None 15830517 Common - putative cytochrome ECs1263 95 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 15831550 Common - putative DMSO reductase anchor subunit ECs2296 25 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 15831849 Common - methyl-accepting protein IV ECs2595 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15833627 Common - DNA-binding transcriptional repressor ECs4373 165 COG0640 ArsR, Predicted transcriptional regulators Transcription 15833449 Common - hypothetical protein ECs4195 33 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 15834006 Common - ATP-dependent DNA helicase RecQ ECs4752 238 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 15831885 Pathogen - putative derepression protein ECs2631 1 None None None 15831636 Common - hypothetical protein ECs2382 6 None None None 15833182 Common - zinc transporter ZupT ECs3928 97 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 15834240 Common - hypothetical protein ECs4986 19 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 15833651 Common - glutamate decarboxylase isozyme ECs4397 67 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 15829832 Common - allantoate amidohydrolase ECs0578 86 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15832251 Pathogen - regulatory protein cIII ECs2997 2 None None None 15832054 Pathogen - hypothetical protein ECs2800 2 None None None 38704185 Common - lipopolysaccharide core biosynthesis protein ECs4507 112 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15833617 Common - hypothetical protein ECs4363 5 None None None 15832712 Common - predicted lipoprotein ECs3458 126 COG4105 ComL, DNA uptake lipoprotein General function prediction only 15833326 Common - hypothetical protein ECs4072 96 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 15834382 Common - elongation factor P ECs5128 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15834335 Common - PhnJ ECs5081 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 15833258 Common - alpha-dehydro-beta-deoxy-D-glucarate aldolase ECs4004 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 15832825 Common - cellobiose/arbutin/salicin-specific PTS system components IIBC ECs3571 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15829266 Pathogen - hypothetical protein ECs0011 2 None None None 15830580 Common - UreF ECs1326 73 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 15829573 Common - hypothetical protein ECs0319 5 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15829900 Common - hypothetical protein ECs0646 70 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15834460 Common - putative ATP-binding component of a transport system ECs5206 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15830371 Common - putative tail assembly protein ECs1117 14 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15830898 Common - minor tail protein ECs1644 13 COG4718 COG4718, Phage-related protein Function unknown 38703922 Common - putative chaperone protein ECs1279 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15830145 Common - threonine and homoserine efflux system ECs0891 76 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 15831061 Common - putative outer membrane protein precursor ECs1807 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 38703927 Pathogen - hypothetical protein ECs5415 1 None None None 15832954 Common - 5-keto-4-deoxyuronate isomerase ECs3700 28 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 15829958 Common asnB asparagine synthetase B ECs0704 156 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 15833259 Common - putative transport protein ECs4005 184 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15829839 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit ECs0585 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 15832373 Common - 2Fe-2S ferredoxin YfaE ECs3119 50 COG0633 Fdx, Ferredoxin Energy production and conversion 15833641 Common - putative ATP-binding component of hemin transport system ECs4387 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 15830828 Common - putative integrase ECs1574 97 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15831583 Common - bifunctional maltose and glucose-specific PTS system components IICB ECs2329 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15829279 Common - hypothetical protein ECs0025 2 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 38704200 Common - putative 2-component regulator ECs4688 95 COG0714 COG0714, MoxR-like ATPases General function prediction only 15832441 Common folX D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase ECs3187 47 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 15830107 Common - biotin synthetase ECs0853 183 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15833140 Common - hypothetical protein ECs3886 55 COG2862 COG2862, Predicted membrane protein Function unknown 15834234 Common - hypothetical protein ECs4980 4 None None None 15830225 Common - cysteine/glutathione ABC transporter membrane/ATP-binding component ECs0971 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 15830605 Common - TerZ ECs1351 28 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 15829820 Common - ureidoglycolate hydrolase ECs0566 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 15832258 Pathogen - hypothetical protein ECs3004 1 None None None 15834590 Common - hypothetical protein ECs5336 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15834609 Common - hypothetical protein ECs5355 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 15831560 Common - multidrug efflux system protein MdtJ ECs2306 141 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 15833458 Common - predicted hydrolase ECs4204 70 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 15831884 Pathogen - hypothetical protein ECs2630 3 None None None 15831768 Common - long-chain-fatty-acid--CoA ligase ECs2514 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 38704131 Common - hypothetical protein ECs3835 25 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 15833473 Common cysG siroheme synthase ECs4219 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 15833508 Common - carboxylesterase BioH ECs4255 133 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15832823 Common - electron transport protein HydN ECs3569 149 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15829907 Common citX 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase ECs0653 24 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 15829362 Common - guanosine 5'-monophosphate oxidoreductase ECs0108 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15834438 Common - hypothetical protein ECs5184 14 COG3061 OapA, Cell envelope opacity-associated protein A Cell envelope biogenesis, outer membrane 15834584 Common - DNA polymerase III subunit psi ECs5330 19 COG3050 HolD, DNA polymerase III, psi subunit DNA replication, recombination, and repair 15833478 Common - hypothetical protein ECs4224 18 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15832343 Common - heme exporter protein B ECs3089 81 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 15830737 Common - hypothetical protein ECs1483 21 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 38703951 Common - dsDNA-mimic protein ECs1748 18 COG3099 COG3099, Uncharacterized protein conserved in bacteria Function unknown 15833037 Pathogen - hypothetical protein ECs3783 1 None None None 15830187 Common - putative sensory transduction regulator ECs0933 13 None None None 15831483 Pathogen - hypothetical protein ECs2229 2 None None None 15833701 Common - xylulokinase ECs4447 181 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15829259 Common - hypothetical protein ECs0005 6 None None None 15831938 Common fliM flagellar motor switch protein FliM ECs2684 110 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 15830374 Common - putative copper/zinc-superoxide dismutase ECs1120 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 15834298 Common - DNA-binding transcriptional dual regulator ECs5044 137 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15833463 Common - hypothetical protein ECs4209 55 COG1289 COG1289, Predicted membrane protein Function unknown 15830328 Common - putative replication protein ECs1074 81 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 15832475 Common - putative outer membrane protein ECs3221 27 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15833587 Common - hypothetical protein ECs4333 101 COG4261 COG4261, Predicted acyltransferase General function prediction only 15832013 Pathogen - hypothetical protein ECs2759 1 None None None 15834019 Common ubiB putative ubiquinone biosynthesis protein UbiB ECs4765 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 15829270 Common - Gef ECs0016 7 None None None 15829490 Common - VgrG ECs0236 60 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 15829360 Common - hypothetical protein ECs0106 44 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 15830496 Common - hypothetical protein ECs1242 18 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 15833926 Common glmU bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase ECs4672 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 15831455 Common - hypothetical protein ECs2201 7 None None None 15833295 Common - hypothetical protein ECs4041 111 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 15833762 Common - 3-deoxy-D-manno-octulosonic-acid transferase ECs4508 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 15832171 Common - putative fimbrial-like protein ECs2917 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832044 Common - hypothetical protein ECs2790 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 162139734 Common - glutamate racemase ECs4898 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 15832837 Common - hydrogenase nickel incorporation protein HypB ECs3583 136 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 15833328 Common - putative ABC transporter ATP-binding protein YrbF ECs4074 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 162139711 Common - dihydroxyacetone kinase subunit DhaK ECs1705 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 15831199 Common - putative replication protein ECs1945 24 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 162139756 Common - DNA-binding transcriptional repressor ExuR ECs3976 132 COG2186 FadR, Transcriptional regulators Transcription 15829853 Common - hypothetical protein ECs0599 4 None None None 15829585 Common - putative NADH-dependent flavin oxidoreductase ECs0331 176 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15831959 Common - chaperone protein HchA ECs2705 49 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15834251 Common - translational regulator ECs4997 3 COG4416 Com, Mu-like prophage protein Com General function prediction only 162139762 Common - anaerobic nitric oxide reductase transcription regulator ECs3565 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 15833522 Common glpE thiosulfate sulfurtransferase ECs4268 95 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15831608 Common - hypothetical protein ECs2354 42 COG1289 COG1289, Predicted membrane protein Function unknown 15830043 Common - DNA-binding transcriptional dual regulator ECs0789 59 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 15830361 Common - putative portal protein ECs1107 36 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 15830430 Pathogen - Gam ECs1176 4 None None None 15833088 Common - hypothetical protein ECs3834 14 None None None 15830035 Common - putative homeobox protein ECs0781 6 None None None 15833067 Common - hypothetical lipoprotein ECs3813 7 None None None 15831706 Common astD succinylglutamic semialdehyde dehydrogenase ECs2452 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15829912 Common - putative sensor-type protein ECs0658 192 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 15830802 Common - hypothetical protein ECs1548 2 None None None 15831698 Common - N,N'-diacetylchitobiose-specific PTS system transporter subunit IIB ECs2444 29 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 15830122 Common - hypothetical protein ECs0868 67 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 15834139 Common - phosphoenolpyruvate carboxylase ECs4885 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 15830113 Common moaA molybdenum cofactor biosynthesis protein A ECs0859 202 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15832911 Common - L-serine dehydratase ECs3657 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 15834550 Pathogen - hypothetical protein ECs5296 3 None None None 15829277 Common - putative fimbrial chaperone ECs0023 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15831720 Common - hypothetical protein ECs2466 8 None None None 15832617 Common - polyphosphate kinase ECs3363 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 15829414 Common - hypothetical protein ECs0160 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 15834357 Common - hypothetical protein ECs5103 40 COG3647 COG3647, Predicted membrane protein Function unknown 15829637 Common - hypothetical protein ECs0383 7 None None None 15832159 Common - hypothetical protein ECs2905 42 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 15833288 Common - hypothetical protein ECs4034 157 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15831929 Pathogen - hypothetical protein ECs2675 4 None None None 15831349 Common - hypothetical protein ECs2095 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15832214 Common - putative protease/scaffold protein ECs2960 128 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15829890 Common - hypothetical protein ECs0636 70 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 38703846 Common - hypoxanthine-guanine phosphoribosyltransferase ECs0129 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 15831797 Common - hypothetical protein ECs2543 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 15829386 Common - hypothetical protein ECs0132 137 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15830934 Common - disulfide bond formation protein B ECs1680 35 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 15831628 Common - hypothetical protein ECs2374 17 None None None 15829842 Common cysS cysteinyl-tRNA synthetase ECs0588 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 38703995 Pathogen - hypothetical protein ECs5452 1 None None None 15831812 Common - DNA damage-inducible protein YebG ECs2558 17 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 15829849 Common - SfmH ECs0595 5 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 38703975 Common - putative transcriptional regulator LYSR-type ECs2027 191 COG0583 LysR, Transcriptional regulator Transcription 15829885 Common - iron-enterobactin transporter periplasmic binding protein ECs0631 55 COG4592 FepB, ABC-type Fe2+-enterobactin transport system, periplasmic component Inorganic ion transport and metabolism 15829396 Common - putative fimbrial protein ECs0142 2 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 38704160 Common - hypothetical protein ECs4197 48 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 15830871 Common - prophage protein NinE ECs1617 2 None None None 15831351 Common - acid sensitivity protein ECs2097 113 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15830824 Common potB spermidine/putrescine ABC transporter membrane protein ECs1570 219 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 15831994 Pathogen - hypothetical protein ECs2740 2 None None None 15829970 Common - LexA regulated protein ECs0716 21 None None None 38703972 Common - hypothetical protein ECs5439 10 COG3042 Hlx, Putative hemolysin General function prediction only 15829882 Common - iron-enterobactin transporter permease ECs0628 190 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 15832887 Common - hypothetical protein ECs3633 162 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 15834155 Common - pantothenate kinase ECs4901 73 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 15832087 Common - H repeat-associated protein ECs2833 2 COG5433 COG5433, Transposase DNA replication, recombination, and repair 15834103 Common - ferredoxin-NADP reductase ECs4849 117 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 15833340 Common - hypothetical protein ECs4086 7 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 15832015 Pathogen - hypothetical protein ECs2761 4 None None None 15833161 Common - DNA-binding response regulator in two-component regulatory system with QseC ECs3907 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15831219 Common - putative antirepressor protein ECs1965 8 None None None 15831778 Common - hypothetical protein ECs2524 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15831326 Common - nitrite extrusion protein 2 ECs2072 79 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 15831952 Common - DNA mismatch endonuclease ECs2698 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 15834517 Common - putative RNA helicase ECs5263 109 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 15833052 Common - D-erythrose 4-phosphate dehydrogenase ECs3798 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15831023 Common - putative phage replication protein ECs1769 5 None None None 15832067 Common sbcB exonuclease I ECs2813 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 15834290 Common - aromatic amino acid aminotransferase ECs5036 88 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15832314 Common fruK 1-phosphofructokinase ECs3060 106 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 15832290 Common - hypothetical protein ECs3036 41 COG2949 SanA, Uncharacterized membrane protein Function unknown 15830478 Pathogen - hypothetical protein ECs1224 3 None None None 15831924 Common - hypothetical protein ECs2670 96 COG2135 COG2135, Uncharacterized conserved protein Function unknown 15829347 Common - FtsW ECs0093 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15830211 Common - pyruvate dehydrogenase ECs0957 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15834012 Common - regulator for metE and metH ECs4758 165 COG0583 LysR, Transcriptional regulator Transcription 15831507 Pathogen - hypothetical protein ECs2253 1 None None None 15830991 Common - response regulator of RpoS ECs1737 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15834587 Common prfC peptide chain release factor 3 ECs5333 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 15829542 Common - hypothetical protein ECs0288 36 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829462 Common - predicted hydroxyacylglutathione hydrolase ECs0208 207 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15834211 Pathogen - hypothetical protein ECs4957 1 None None None 15829863 Common - DNA-binding response regulator in two-component regulatory system with CusS ECs0609 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15833867 Pathogen - ilvB operon leader peptide ECs4613 1 None None None 15829341 Common ftsL cell division protein FtsL ECs0087 25 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 15829497 Common - hypothetical protein ECs0243 1 None None None 15831028 Common - hypothetical protein ECs1774 2 None None None 15832757 Common - hypothetical protein ECs3503 12 None None None 15833002 Common - putative synthase ECs3748 119 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 38704234 Common aspA aspartate ammonia-lyase ECs5120 219 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 15834226 Common - putative virion morphogenesis protein ECs4972 5 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 15830590 Common - hypothetical protein ECs1336 57 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830248 Common rpsA 30S ribosomal protein S1 ECs0994 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 15829877 Common - outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D ECs0623 111 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 15832472 Common - putative fimbrial protein ECs3218 9 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15834041 Common - GTPase EngB ECs4787 181 COG0218 COG0218, Predicted GTPase General function prediction only 15829318 Common - DNA polymerase II ECs0064 64 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 15830528 Common - putative transcriptional regulator ECs1274 4 COG3710 CadC, DNA-binding winged-HTH domains Transcription 15830267 Common asnC asparaginyl-tRNA synthetase ECs1013 238 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15833041 Common - methylmalonyl-CoA mutase ECs3787 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 15832430 Common - putative transport protein ECs3176 122 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15832144 Pathogen - hypothetical protein ECs2890 1 None None None 15834343 Common - hypothetical protein ECs5089 65 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 15830252 Common lpxK tetraacyldisaccharide 4'-kinase ECs0998 127 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 15834540 Common - isoaspartyl dipeptidase ECs5286 44 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 15831595 Common - SoxR-reducing system protein RsxE ECs2341 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 15831495 Common - putative tail protein ECs2241 3 None None None 15831404 Common - hypothetical protein ECs2150 7 None None None 15831475 Common - putative transposase ECs2221 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831916 Common - flagellin ECs2662 115 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 38704149 Common - isoprenoid biosynthesis protein with amidotransferase-like domain ECs4088 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 38704221 Common zraP zinc resistance protein ECs4925 5 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 15833104 Common - putative virulence-related membrane protein ECs3850 12 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15834456 Common - antitoxin ChpS ECs5202 21 COG2336 MazE, Growth regulator Signal transduction mechanisms 15830007 Common sucC succinyl-CoA synthetase subunit beta ECs0753 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 15833958 Common - branched-chain amino acid aminotransferase ECs4704 220 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15832336 Common - DNA-binding response regulator in two-component regulatory system with NarQ or NarX ECs3082 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15832443 Common - hypothetical protein ECs3189 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 15834279 Common - diacylglycerol kinase ECs5025 92 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 15832805 Common - hypothetical protein ECs3551 73 COG1238 COG1238, Predicted membrane protein Function unknown 15829601 Pathogen - hypothetical protein ECs0347 2 None None None 15830342 Common - hypothetical protein ECs1088 3 None None None 15833424 Common rplF 50S ribosomal protein L6 ECs4170 226 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 15833379 Common - putative dehydrogenase ECs4125 94 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 15831416 Common - putative tail assembly protein ECs2162 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 15834320 Common - hypothetical protein ECs5066 44 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 38704127 Common - methylmalonyl-CoA decarboxylase ECs3789 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 15831046 Common - putative terminase large subunit ECs1792 35 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 15833640 Common - putative hemin permease ECs4386 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15830163 Common - putative transport protein ECs0909 212 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15833901 Common - multidrug efflux system protein MdtL ECs4647 212 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830254 Common - hypothetical protein ECs1000 95 COG2835 COG2835, Uncharacterized conserved protein Function unknown 15832306 Common - predicted kinase ECs3052 121 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15830554 Pathogen - hypothetical protein ECs1300 2 None None None 15832096 Common - O antigen flippase ECs2842 16 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15832647 Common hscB co-chaperone HscB ECs3393 57 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 15833048 Common - arginine exporter protein ECs3794 85 COG1279 COG1279, Lysine efflux permease General function prediction only 15831402 Common - L-allo-threonine dehydrogenase, NAD(P)-binding ECs2148 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 15831630 Common - hypothetical protein ECs2376 6 None None None 15834451 Common - methionine sulfoxide reductase A ECs5197 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15834311 Common - formate-dependent nitrite reductase complex subunit NrfF ECs5057 86 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 15830441 Common - CII ECs1187 1 None None None 162139812 Common - pyridine nucleotide-disulfide oxidoreductase ECs0342 237 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15830883 Common - terminase small subunit ECs1629 10 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 15833671 Common - hypothetical protein ECs4417 6 None None None 15832500 Common - multidrug resistance protein Y ECs3246 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830966 Common - ribose-phosphate pyrophosphokinase ECs1712 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15830811 Common - putative antirepressor protein ECs1557 41 COG3617 COG3617, Prophage antirepressor Transcription 15831283 Common mdoD glucan biosynthesis protein D ECs2029 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 15832576 Common - hypothetical protein ECs3322 19 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 15830198 Common artM arginine transporter permease subunit ArtM ECs0944 170 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 38703909 Common - putative regulatory protein ECs1069 9 COG2944 COG2944, Predicted transcriptional regulator Transcription 15833490 Common - hypothetical protein ECs4236 6 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 38704253 Common - hypothetical protein ECs5591 3 None None None 15833024 Common - putative global regulator ECs3770 101 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 15832948 Common - DNA-binding transcriptional repressor ECs3694 128 COG1609 PurR, Transcriptional regulators Transcription 15830084 Common - hypothetical protein ECs0830 7 COG5471 COG5471, Uncharacterized conserved protein Function unknown 15833465 Common - para-aminobenzoate synthase component II ECs4211 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 15829731 Common - thiamine biosynthesis protein ThiI ECs0477 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 15833494 Common - putative dehydrogenase ECs4240 11 None None None 38704161 Common - hypothetical protein ECs5532 21 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 15830696 Common - glutaredoxin 2 ECs1442 19 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 162139817 Common - hypothetical protein ECs0123 21 COG3112 COG3112, Uncharacterized protein conserved in bacteria Function unknown 15832489 Common - hypothetical protein ECs3235 3 None None None 15832761 Pathogen - hypothetical protein ECs3507 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 15830701 Common - MviN ECs1447 193 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 15829568 Common - hypothetical protein ECs0314 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 15829899 Common - alkyl hydroperoxide reductase F52a subunit ECs0645 246 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 15834431 Common - primosomal replication protein N ECs5177 25 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 15830833 Pathogen - hypothetical protein ECs1579 1 None None None 15834416 Common - putative synthetase/amidase ECs5162 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 15833945 Common - D-ribose transporter ATP binding protein ECs4691 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15830653 Pathogen - hypothetical protein ECs1399 3 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 15834197 Pathogen - putative regulatory protein ECs4943 2 None None None 15833786 Common - alpha-xylosidase YicI ECs4532 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 15829919 Common tatE twin arginine translocase protein E ECs0665 6 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 15831671 Common - predicted glutathione peroxidase ECs2417 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 38704049 Common - hypothetical protein ECs2888 31 COG3422 COG3422, Uncharacterized conserved protein Function unknown 15833860 Common - DNA-binding response regulator in two-component regulatory system wtih UhpB ECs4606 185 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15829757 Common - putative multidrug transporter membrane\ATP-binding components ECs0503 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15829420 Common - carbohydrate diacid transcriptional activator CdaR ECs0166 49 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 15830565 Common - putative transposase ECs1311 147 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 38703902 Common - anaerobic dimethyl sulfoxide reductase subunit A ECs0979 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15829612 Common - betaine aldehyde dehydrogenase ECs0358 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15831482 Pathogen - hypothetical protein ECs2228 1 None None None 15831419 Common - putative minor tail protein ECs2165 13 COG4718 COG4718, Phage-related protein Function unknown 15830063 Common - exonuclease ECs0809 13 None None None 15833426 Common rpsN 30S ribosomal protein S14 ECs4172 209 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 15832150 Common - galactitol-specific PTS system component IIB ECs2896 15 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 15833855 Common - hypothetical protein ECs4601 134 COG2252 COG2252, Permeases General function prediction only 15829654 Common - hypothetical protein ECs0400 32 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 162139785 Common - hypothetical protein ECs2566 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15830433 Common - Ea10 ECs1179 1 None None None 15832555 Common - hypothetical protein ECs3301 138 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 15830139 Common - putative SAM-dependent methyltransferase ECs0885 28 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 15831544 Common - spermidine N1-acetyltransferase ECs2290 100 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15831125 Common - peptide transport-like protein ECs1871 196 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15833597 Common - periplasmic binding protein for nickel ECs4343 211 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15829964 Common - glutaminyl-tRNA synthetase ECs0710 242 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15833528 Common glgA glycogen synthase ECs4274 133 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 15832191 Common - putative 2-component sensor protein ECs2937 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 15829833 Common - ureidoglycolate dehydrogenase ECs0579 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 15831780 Pathogen - hypothetical protein ECs2526 2 None None None 38703936 Common lolD lipoprotein transporter ATP-binding subunit ECs1495 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15832930 Common RecD exonuclease V subunit alpha ECs3676 141 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 15832997 Common - hypothetical protein ECs3743 231 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 15829300 Common - putative oxidoreductase FixC ECs0046 134 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15829375 Common - hypothetical protein ECs0121 32 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 38703979 Common - putative DNA-binding transcriptional regulator ECs2054 93 COG1802 GntR, Transcriptional regulators Transcription 15834171 Common thiC thiamine biosynthesis protein ThiC ECs4917 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 15833923 Common - putative fimbrial chaperone ECs4669 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15830774 Common - prophage maintenance protein ECs1520 7 None None None 38703912 Pathogen - putative minor tail protein ECs1112 3 None None None 15834026 Common fre FMN reductase ECs4772 103 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 15830907 Common - hypothetical protein ECs1653 27 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 15832630 Common hisS histidyl-tRNA synthetase ECs3376 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 38704135 Common - putative glutathione S-transferase YghU ECs3874 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15833961 Common - DNA-binding transcriptional regulator IlvY ECs4707 190 COG0583 LysR, Transcriptional regulator Transcription 15830939 Common dadX alanine racemase ECs1685 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 15832003 Common - hypothetical protein ECs2749 14 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 15833624 Common - oligopeptidase A ECs4370 126 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 15829763 Common - hypothetical protein ECs0509 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 15834272 Common - maltose/maltodextrin transporter ATP-binding protein ECs5018 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 15829868 Common - phenylalanine transporter ECs0614 161 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 38704040 Common - hypothetical protein ECs2809 22 COG2926 COG2926, Uncharacterized protein conserved in bacteria Function unknown 15830455 Common - NinG ECs1201 12 None None None 15832439 Common - hypothetical protein ECs3185 52 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 15832699 Common - autonomous glycyl radical cofactor GrcA ECs3445 52 COG3445 COG3445, Acid-induced glycyl radical enzyme General function prediction only 15832416 Common - NADH dehydrogenase subunit L ECs3162 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 15832049 Common - putative transposase ECs2795 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832925 Common - hypothetical protein ECs3671 94 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 15830130 Pathogen - hypothetical protein ECs0876 3 None None None 15832644 Common - hypothetical protein ECs3390 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 15830921 Common - hypothetical protein ECs1667 19 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15832388 Common - hypothetical protein ECs3134 96 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15829796 Common - hypothetical protein ECs0542 192 None None None 15829487 Common - hypothetical protein ECs0233 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 15831092 Common - hypothetical protein ECs1838 115 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 15831212 Common - putative antitermination protein ECs1958 4 None None None 15832492 Common - hypothetical protein ECs3238 2 None None None 15832816 Common - DNA-binding transcriptional activator of glucitol operon ECs3562 12 COG4578 GutM, Glucitol operon activator Transcription 15833784 Common - putative transport protein ECs4530 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15833191 Common - hypothetical protein ECs3937 59 COG3025 COG3025, Uncharacterized conserved protein Function unknown 15832269 Common - putative transport system permease protein ECs3015 143 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 38703917 Common - hypothetical protein ECs1253 101 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 38703982 Common - hypothetical protein ECs5442 11 COG5433 COG5433, Transposase DNA replication, recombination, and repair 15831865 Common - hypothetical protein ECs2611 2 None None None 15832163 Pathogen - hypothetical protein ECs2909 1 None None None 15830000 Common sdhC succinate dehydrogenase cytochrome b556 large membrane subunit ECs0746 92 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 15830612 Common - TerF ECs1358 24 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 15833207 Common - hypothetical protein ECs3953 70 COG1695 COG1695, Predicted transcriptional regulators Transcription 15833009 Common - putative transport protein ECs3755 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15833876 Common - putative 6-phospho-beta-glucosidase ECs4622 53 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 15831190 Common kil Rac prophage killing protein ECs1936 3 None None None 15834031 Common - potassium transporter ECs4777 149 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15829953 Common - hypothetical protein ECs0699 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15829480 Common - hypothetical lipoprotein ECs0226 13 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 15832657 Common - DNA-binding transcriptional activator of 3-phenylpropionic acid catabolism ECs3403 189 COG0583 LysR, Transcriptional regulator Transcription 15832949 Common - diaminopimelate decarboxylase ECs3695 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 15829708 Pathogen - hypothetical protein ECs0454 1 None None None 15830998 Common oppB oligopeptide transporter permease ECs1744 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15832425 Common - NADH dehydrogenase subunit B ECs3171 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 15834375 Common fxsA FxsA ECs5121 14 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 15833979 Common - putative cytochrome ECs4725 24 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15834327 Common - putative ATP-binding component of sugar ABC transporter ECs5073 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15829682 Common - hypothetical protein ECs0428 18 None None None 15829305 Common folA dihydrofolate reductase ECs0051 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 15832424 Common - bifunctional NADH:ubiquinone oxidoreductase subunit C/D ECs3170 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 15833156 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase ECs3902 89 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15833304 Common nusA transcription elongation factor NusA ECs4050 216 COG0195 NusA, Transcription elongation factor Transcription 15834095 Common pfkA 6-phosphofructokinase ECs4841 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 15833695 Common - major cold shock protein ECs4441 181 COG1278 CspC, Cold shock proteins Transcription 15833808 Pathogen - EspB ECs4554 1 None None None 15831634 Common - hypothetical protein ECs2380 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 15829477 Common - putative ATP-dependent Clp proteinase ATP-binding chain ECs0223 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15830480 Pathogen - hypothetical protein ECs1226 3 None None None 15834466 Common - peptidase PmbA ECs5212 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15832509 Common - hypothetical protein ECs3255 5 None None None 15831942 Common fliQ flagellar biosynthesis protein FliQ ECs2688 70 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 15829450 Common - prolyl-tRNA synthetase ECs0196 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15831564 Common - hypothetical protein ECs2310 11 None None None 15833609 Common gatY putative fructose-1,6-bisphosphate aldolase ECs4355 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15830418 Common - hypothetical protein ECs1164 3 None None None 15832562 Common - transcriptional regulator EutR ECs3308 57 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15833542 Common - hypothetical protein ECs4288 146 COG1741 COG1741, Pirin-related protein General function prediction only 162139721 Common - hypothetical protein ECs4051 181 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 15830153 Common - hypothetical protein ECs0899 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15832464 Common - putative transporting ATPase ECs3210 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 15830191 Common - putrescine transporter subunit: membrane component of ABC superfamily ECs0937 173 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 15833060 Common - fructose-1,6-bisphosphatase II-like protein ECs3806 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 15832362 Common - hypothetical protein ECs3108 13 COG4676 COG4676, Uncharacterized protein conserved in bacteria Function unknown 38704039 Common - hypothetical protein ECs2774 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 15830013 Common - hypothetical protein ECs0759 16 None None None 15830751 Common - N-acetyl-D-glucosamine kinase ECs1497 143 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15829299 Common fixB putative electron transfer flavoprotein FixB ECs0045 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 15830115 Common moaC molybdenum cofactor biosynthesis protein C ECs0861 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15829459 Common - hypothetical protein ECs0205 31 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 15831873 Pathogen - hypothetical protein ECs2619 4 None None None 162139775 Common - hybrid sensory kinase in two-component regulatory system with RcsB and YojN ECs3107 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15832895 Common mazG nucleoside triphosphate pyrophosphohydrolase ECs3641 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 15831261 Common - putative BigB-like protein ECs2007 24 None None None 15830942 Common - murein transglycosylase E ECs1687 64 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15833020 Common xerD site-specific tyrosine recombinase XerD ECs3766 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15834556 Common - putative regulator ECs5302 226 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 15833202 Common rpsU 30S ribosomal protein S21 ECs3948 153 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 15834426 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase ECs5172 54 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 38704143 Common - N-acetylgalactosamine-specific PTS system transporter subunit IIB ECs4011 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 15833239 Common - putative cytochrome ECs3985 69 COG3152 COG3152, Predicted membrane protein Function unknown 15830317 Pathogen - hypothetical protein ECs1063 1 None None None 15832332 Common - nucleoid-associated protein NdpA ECs3078 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 15833413 Common rplQ 50S ribosomal protein L17 ECs4159 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 15831472 Common - hypothetical protein ECs2218 2 None None None 15832223 Common - putative holin protein ECs2969 5 None None None 15832181 Common - hypothetical protein ECs2927 50 COG0714 COG0714, MoxR-like ATPases General function prediction only 15833526 Common - hypothetical membrane protein ECs4272 99 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 15833119 Common - hypothetical protein ECs3865 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 38703876 Common - hypothetical protein ECs0590 32 COG2501 COG2501, Uncharacterized conserved protein Function unknown 15832149 Common - PTS system galactitol-specific enzyme IIC ECs2895 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 15833730 Common - mannitol-1-phosphate 5-dehydrogenase ECs4476 91 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15831748 Common - hypothetical protein ECs2494 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15830877 Common - putative endopeptidase ECs1623 9 None None None 38704068 Common - hypothetical protein ECs5486 12 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 15834586 Common - nucleotidase ECs5332 112 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15830978 Common - hypothetical protein ECs1724 27 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 15830975 Common - calcium/sodium:proton antiporter ECs1721 48 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 15832849 Common - RNA polymerase sigma factor RpoS ECs3595 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15829435 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase ECs0181 177 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 15829523 Common - gamma-glutamyl kinase ECs0269 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 15832220 Common - lipoprotein Rz1 precursor ECs2965 1 None None None 15829803 Pathogen - hypothetical protein ECs0549 2 None None None 15833570 Common - putative receptor ECs4316 8 None None None 38704058 Common - putative regulatory protein ECs3032 190 COG0583 LysR, Transcriptional regulator Transcription 15832140 Common - signal transduction histidine-protein kinase BaeS ECs2886 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15833149 Common - putative oxidoreductase ECs3894 162 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 15830734 Common - ferric-rhodotorulic acid outer membrane transporter ECs1480 106 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 15829984 Common - hypothetical protein ECs0730 1 None None None 15830892 Pathogen - minor tail protein ECs1638 4 None None None 15830748 Common - outer membrane-specific lipoprotein transporter subunit LolC ECs1494 155 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15831758 Common - hypothetical protein ECs2504 40 COG2261 COG2261, Predicted membrane protein Function unknown 15833953 Common - hypothetical protein ECs4699 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 15829656 Common - 3-(3-hydroxyphenyl)propionate hydroxylase ECs0402 108 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 15829449 Common - hypothetical protein ECs0195 5 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15832846 Common - putative 4-hydroxybenzoate decarboxylase ECs3592 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 15830594 Common - hypothetical protein ECs1340 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834366 Common - putative peptide transporter ECs5112 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 15832543 Common - glucose-specific PTS system component ECs3289 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 15829724 Common - thiamine monophosphate kinase ECs0470 195 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 15829675 Common - taurine transporter subunit ECs0421 201 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 15831891 Common - putative transposase ECs2637 29 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 38704072 Common - NADH dehydrogenase subunit A ECs3172 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 15830556 Common - putative regulatory protein ECs1302 22 COG3311 AlpA, Predicted transcriptional regulator Transcription 15832112 Common - GDP-D-mannose dehydratase ECs2858 228 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 15829379 Common - spermidine synthase ECs0125 126 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 15833317 Common - hypothetical protein ECs4063 73 COG2962 RarD, Predicted permeases General function prediction only 38703906 Common - hypothetical protein ECs1050 25 COG3785 COG3785, Uncharacterized conserved protein Function unknown 15834530 Common - FimD ECs5276 34 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 38703939 Common - hypothetical protein ECs5419 47 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834293 Common - hypothetical protein ECs5039 36 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 15833680 Common - putative fimbrial protein precursor ECs4426 11 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15830088 Common - putative major tail protein ECs0834 4 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15830661 Common - hypothetical protein ECs1407 6 None None None 15829597 Common - putative ARAC-type regulatory protein ECs0343 122 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15833362 Common - serine endoprotease ECs4108 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 38703986 Common - biofilm-dependent modulation protein ECs2085 4 None None None 15832981 Common - EivJ ECs3727 2 None None None 15831187 Common recT recombination and repair protein RecT ECs1933 27 COG3723 RecT, Recombinational DNA repair protein (RecE pathway) DNA replication, recombination, and repair 15833273 Common - N-acetylgalactosamine-specific PTS system transporter subunit IID ECs4019 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 15830099 Pathogen - hypothetical protein ECs0845 1 None None None 38704064 Pathogen - hypothetical protein ECs5484 1 None None None 15829424 Common - methionine aminopeptidase ECs0170 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 162139803 Common mgsA methylglyoxal synthase ECs1047 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 15834471 Common - trehalose(maltose)-specific PTS system components IIBC ECs5217 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15830706 Common flgC flagellar basal body rod protein FlgC ECs1452 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 15829492 Common - hypothetical protein ECs0238 6 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15832993 Common - xanthine dehydrogenase subunit XdhA ECs3739 118 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 38704078 Common - lipid A biosynthesis palmitoleoyl acyltransferase ECs3258 96 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 15834077 Common - putative frv operon regulatory protein ECs4823 10 COG3711 BglG, Transcriptional antiterminator Transcription 15832219 Common - putative endopeptidase ECs2966 9 None None None 15831830 Common aspS aspartyl-tRNA synthetase ECs2576 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15833728 Common - hypothetical protein ECs4474 15 None None None 15831987 Common - putative portal protein ECs2733 36 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 15830352 Pathogen - hypothetical protein ECs1097 1 None None None 15831377 Common - putative LACI-type transcriptional regulator ECs2123 52 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15834165 Common - DNA-directed RNA polymerase subunit beta' ECs4911 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15831155 Common - hypothetical protein ECs1901 42 COG3768 COG3768, Predicted membrane protein Function unknown 15831525 Pathogen - hypothetical protein ECs2271 1 None None None 15829992 Common - hypothetical protein ECs0738 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 15833264 Common - putative tagatose 6-phosphate kinase 2 ECs4010 34 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 15830547 Common - hypothetical protein ECs1293 2 None None None 15834526 Common - tyrosine recombinase/inversion of on/off regulator of fimA ECs5272 213 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15831273 Pathogen - hypothetical protein ECs2019 1 None None None 38704266 Common - hypothetical protein ECs5362 1 None None None 15833440 Common rpsJ 30S ribosomal protein S10 ECs4186 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 15833016 Common lysS lysyl-tRNA synthetase ECs3762 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15831843 Common flhA flagellar biosynthesis protein A ECs2589 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 15831944 Common - transcriptional regulator for ctr capsule biosynthesis ECs2690 10 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 38704177 Common - phosphoethanolamine transferase ECs4425 63 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15833794 Common - hypothetical protein ECs4540 6 None None None 15832018 Common - hypothetical protein ECs2764 5 None None None 38703896 Common - hypothetical protein ECs5399 28 COG2944 COG2944, Predicted transcriptional regulator Transcription 15831682 Common - hypothetical protein ECs2428 35 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 15829257 Common - homoserine kinase ECs0003 129 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 15833705 Common - putative membrane component of xylose transport system ECs4451 109 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 15831533 Pathogen - hypothetical protein ECs2279 3 None None None 15832907 Common - SecY interacting protein Syd ECs3653 19 None None None 15833292 Common - hypothetical protein ECs4038 33 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 15830716 Common rne ribonuclease E ECs1462 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 15832155 Common - putative nucleoside permease protein ECs2901 57 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15834127 Common - hypothetical protein ECs4873 17 COG3738 COG3738, Uncharacterized protein conserved in bacteria Function unknown 15831041 Common - lipoprotein Rz1 precursor ECs1787 1 None None None 15833720 Common - putative alcohol dehydrogenase ECs4466 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 15829348 Common murG N-acetylglucosaminyl transferase ECs0094 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15833261 Common - putative regulator PrlF ECs4007 11 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 15831216 Common - putative holin protein ECs1962 5 None None None 15832937 Common - hypothetical protein ECs3683 10 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 15833406 Common def peptide deformylase ECs4152 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 15829947 Common - glutamate/aspartate transport system permease ECs0693 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15829321 Common - ribulokinase ECs0067 83 COG1069 AraB, Ribulose kinase Energy production and conversion 15832980 Common - surface presentation of antigens protein SpaO ECs3726 10 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15829768 Common - hypothetical protein ECs0514 10 None None None 15833391 Common - transmembrane protein affects septum formation and cell membrane permeability ECs4137 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15829690 Common proC pyrroline-5-carboxylate reductase ECs0437 215 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 15830917 Common - outer membrane protease ECs1663 12 COG4571 OmpT, Outer membrane protease Cell envelope biogenesis, outer membrane 15834503 Common - putative resolvase ECs5249 128 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15833211 Common - DNA-binding transcriptional repressor ECs3957 125 COG1609 PurR, Transcriptional regulators Transcription 15831309 Common - putative outer membrane receptor for iron transport ECs2055 127 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 38704193 Common - sensory histidine kinase UhpB ECs4605 106 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 15832726 Common rpsP 30S ribosomal protein S16 ECs3472 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 15831202 Pathogen - hypothetical protein ECs1948 3 None None None 15833285 Common - hypothetical protein ECs4031 69 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 15833450 Common - hypothetical protein ECs4196 42 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 162139759 Common tolC outer membrane channel protein ECs3923 131 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15833231 Common - hypothetical protein ECs3977 156 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15831817 Common - DNA-binding transcriptional regulator HexR ECs2563 99 COG1737 RpiR, Transcriptional regulators Transcription 15829824 Common - tartronic semialdehyde reductase ECs0570 183 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 15833534 Common - putative DNA processing chain A ECs4280 180 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 15829507 Common - DinJ ECs0253 34 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 15833747 Common - predicted glycosyl transferase ECs4493 205 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15832345 Common - cytochrome c-type protein NapC ECs3091 49 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 15833444 Common tuf elongation factor Tu ECs4190 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15830570 Common - putative diacylglycerol kinase ECs1316 89 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 15831112 Common - RNase II stability modulator ECs1858 181 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 15830610 Common - TerE ECs1356 29 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 38704023 Common pphA serine/threonine protein phosphatase 1 ECs2548 96 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 15834008 Common rhtB homoserine/homoserine lactone efflux protein ECs4754 117 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 15831370 Common - putative ATP-binding component of a transport system and adhesin protein ECs2116 25 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15832986 Common - EivE ECs3732 7 None None None 15834177 Common - transcriptional regulator HU subunit alpha ECs4923 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15831869 Common - tyrosine-specific transport system ECs2615 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15830909 Common - hypothetical protein ECs1655 11 None None None 15833339 Common - phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) ECs4085 129 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 15829293 Common - carnitinyl-CoA dehydratase ECs0039 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 15830785 Common - hypothetical protein ECs1531 3 None None None 15829500 Common - hypothetical protein ECs0246 187 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15831976 Common - putative tail assembly protein ECs2722 14 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15833453 Common - hypothetical protein ECs4199 21 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 15831642 Common - cysteine desulfurase activator complex subunit SufD ECs2388 174 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 15832210 Common - hypothetical membrane protein ECs2956 4 COG5471 COG5471, Uncharacterized conserved protein Function unknown 38704101 Common - hypothetical protein ECs3400 113 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 15834101 Common - hypothetical protein ECs4847 14 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 15830382 Common - hydrogenase-1 small subunit ECs1128 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 15829263 Common mogA molybdenum cofactor biosynthesis protein ECs0009 184 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 15832327 Common - hypothetical protein ECs3073 11 None None None 15829581 Common rpmE2 50S ribosomal protein L31 type B ECs0327 107 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15831033 Common - hypothetical lipoprotein ECs1779 3 None None None 38703847 Common - hypothetical protein ECs0151 91 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 15830899 Common - minor tail protein ECs1645 14 COG4672 gp18, Phage-related protein Function unknown 38703883 Common - citrate lyase beta chain ECs0655 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 15829770 Common - acridine efflux pump ECs0516 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15833142 Pathogen - hypothetical protein ECs3888 2 None None None 15830325 Common - hypothetical protein ECs1071 5 None None None 15829980 Common - potassium-transporting ATPase subunit A ECs0726 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 15829738 Common - cytochrome o ubiquinol oxidase subunit III ECs0484 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 15833648 Common - putative transport system permease protein ECs4394 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 15829324 Common thiQ thiamin transporter ATP-binding subunit ECs0070 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 15833585 Common - putative surfactin synthetase ECs4331 45 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15830677 Common - hypothetical protein ECs1423 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 15831677 Common rplT 50S ribosomal protein L20 ECs2423 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 15829896 Common - putative transcriptional regulator LYSR-type ECs0642 116 COG0583 LysR, Transcriptional regulator Transcription 15832827 Common hycI hydrogenase 3 maturation protease ECs3573 37 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 15833252 Common - DNA-binding transcriptional activator ECs3998 187 COG0583 LysR, Transcriptional regulator Transcription 162139758 Common - hypothetical protein ECs3925 21 COG5463 COG5463, Predicted integral membrane protein Function unknown 15832854 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ECs3600 187 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 15831344 Common - hypothetical protein ECs2090 215 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15832873 Common cysJ sulfite reductase subunit alpha ECs3619 106 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 15833936 Common gidB glucose-inhibited division protein B ECs4682 202 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 15832944 Common - hypothetical protein ECs3690 14 None None None 15829556 Common - Cnr-like protein ECs0302 4 None None None 15833755 Common - lipopolysaccharide 1,2-N- acetylglucosaminetransferase ECs4501 197 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15834384 Common - outer membrane lipoprotein Blc ECs5130 69 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 15833619 Common - low-affinity phosphate transport ECs4365 150 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 15830826 Common - peptidase T ECs1572 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 15831599 Common - pyridoxamine kinase ECs2345 67 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 38703920 Pathogen - hypothetical protein ECs5411 2 None None None 15833070 Common - hypothetical protein ECs3816 3 None None None 15833222 Common - hypothetical protein ECs3968 48 COG2949 SanA, Uncharacterized membrane protein Function unknown 15832375 Common - putative antibiotic resistance protein ECs3121 168 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15831075 Pathogen - hypothetical protein ECs1821 2 None None None 15833481 Common - phosphoglycolate phosphatase ECs4227 217 COG0546 Gph, Predicted phosphatases General function prediction only 15829729 Common - geranyltranstransferase ECs0475 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15833130 Common hypA hydrogenase nickel incorporation protein HybF ECs3876 96 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 15832060 Common - hypothetical protein ECs2806 8 None None None 15830143 Common glnH glutamine ABC transporter periplasmic protein ECs0889 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15834570 Common - putative transport protein ECs5316 207 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15833420 Common rplO 50S ribosomal protein L15 ECs4166 70 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 15830927 Pathogen - hypothetical protein ECs1673 1 None None None 15831907 Common - hypothetical protein ECs2653 10 None None None 15832736 Common smpB SsrA-binding protein ECs3482 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 15830562 Common - hypothetical protein ECs1308 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831063 Pathogen - hypothetical protein ECs1809 1 None None None 15833908 Pathogen - hypothetical protein ECs4654 1 None None None 15834262 Common pgi glucose-6-phosphate isomerase ECs5008 198 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 15830404 Common - DNA-binding response regulator in two-component regulatory system with TorS ECs1150 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15831178 Common - hypothetical protein ECs1924 75 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 15833035 Common - Z-ring-associated protein ECs3781 47 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 15834160 Common rplK 50S ribosomal protein L11 ECs4906 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 15832046 Common - hypothetical protein ECs2792 130 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 15831814 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ECs2560 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 15830105 Common - predicted kinase inhibitor ECs0851 127 COG1881 COG1881, Phospholipid-binding protein General function prediction only 15834341 Common - periplasmic binding protein component of Pn transporter ECs5087 86 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 15831718 Common - putative cytochrome oxidase ECs2464 52 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15832832 Common - membrane-spanning protein of hydrogenase 3 ECs3578 177 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 15834072 Common - formate dehydrogenase-O subunit gamma ECs4818 71 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 38703866 Common - putative transport protein ECs0481 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15829927 Common - penicillin-binding protein 2 ECs0673 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15830607 Common - TerB ECs1353 16 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 15830637 Common - hypothetical protein ECs1383 6 None None None 15831098 Common - predicted inner membrane peptidase ECs1844 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15831766 Common - putative diogenase beta subunit ECs2512 108 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 15833825 Pathogen - SepZ ECs4571 1 None None None 15831590 Common - Na(+)-translocating NADH-quinone reductase subunit E ECs2336 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 15833968 Common trxA thioredoxin ECs4714 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15833241 Common - putative transcriptional regulator LYSR-type ECs3987 153 COG0583 LysR, Transcriptional regulator Transcription 15834596 Common - phosphopentomutase ECs5342 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 15829550 Common - putative Ogr family transcription activator ECs0296 7 None None None 15830269 Common - aminopeptidase N ECs1015 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 15830494 Pathogen - hypothetical protein ECs1240 1 None None None 15832056 Common - putative antirestriction protein ECs2802 16 None None None 15830389 Common - putative third cytochrome oxidase subunit II ECs1135 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 15831887 Common - putative phage replication protein ECs2633 17 None None None 15829920 Common - lipoyl synthase ECs0666 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 15830582 Common - hypothetical protein ECs1328 46 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830503 Pathogen - hypothetical protein ECs1249 2 None None None 15830681 Common - glucosyltransferase MdoH ECs1427 54 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 15832275 Common pbpG D-alanyl-D-alanine endopeptidase ECs3021 152 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15831936 Common - flagellar hook-length control protein ECs2682 45 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 15831054 Common - putative major tail subunit ECs1800 6 None None None 15832394 Common - aluminum-inducible protein ECs3140 4 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 15831135 Common - phage shock protein ECs1881 65 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 15832752 Common - hypothetical protein ECs3498 3 None None None 15830569 Pathogen - hypothetical protein ECs1315 1 None None None 15832786 Common - hypothetical protein ECs3532 8 None None None 15830002 Common sdhA succinate dehydrogenase flavoprotein subunit ECs0748 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 15829785 Common - putative cation:proton antiport protein ECs0531 215 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 15834309 Common - NrfD ECs5055 29 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 15831965 Common - hypothetical protein ECs2711 19 COG3443 COG3443, Predicted periplasmic or secreted protein General function prediction only 15832417 Common - NADH dehydrogenase subunit K ECs3163 67 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 15832236 Common - hypothetical protein ECs2982 14 None None None 15834301 Common - hypothetical protein ECs5047 108 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 15831447 Common - putative ante-terminator protein ECs2193 4 None None None 15832188 Common - hypothetical protein ECs2934 8 COG4808 COG4808, Uncharacterized protein conserved in bacteria Function unknown 38703842 Common - 3-isopropylmalate dehydrogenase ECs0077 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 15829339 Common - hypothetical protein ECs0085 144 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 15833018 Common - ssDNA exonuclease RecJ ECs3764 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15831426 Pathogen - putative tail attachment protein ECs2172 3 None None None 15834603 Common - putative ABC transporter ATP-binding protein ECs5349 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15832673 Common - regulatory protein P-II for glutamine synthetase ECs3419 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15829713 Common secD preprotein translocase subunit SecD ECs0459 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 15833911 Pathogen - hypothetical protein ECs4657 2 None None None 15829632 Common - putative ABC transport system permease ECs0378 136 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 15832446 Common - histidine transport system permease protein ECs3192 170 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 15832975 Common - surface presentation of antigens protein SpaS ECs3721 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 15833853 Common - hypothetical protein ECs4599 8 None None None 15829943 Common - putative DnaK ECs0689 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15831786 Common rrmA 23S rRNA methyltransferase A ECs2532 91 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15832065 Common - DNA gyrase inhibitor ECs2811 26 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 38703932 Common flgI flagellar basal body P-ring protein ECs1458 104 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 15832721 Common - hypothetical protein ECs3467 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15833330 Common - D-arabinose 5-phosphate isomerase ECs4076 151 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 15830027 Common - colicin uptake protein TolR ECs0773 103 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 15833357 Common rpsI 30S ribosomal protein S9 ECs4103 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 15831171 Common - hypothetical protein ECs1917 39 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 15830916 Common - hypothetical protein ECs1662 31 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15834393 Common - phosphatidylserine decarboxylase ECs5139 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 15829555 Common - hypothetical protein ECs0301 3 None None None 15832965 Common - hypothetical protein ECs3711 27 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15829440 Common dnaE DNA polymerase III subunit alpha ECs0186 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 15832022 Common - putative cell division inhibition protein ECs2768 1 None None None 15831588 Common - oriC-binding nucleoid-associated protein ECs2334 12 None None None 15834455 Pathogen - hypothetical protein ECs5201 2 None None None 15830103 Pathogen - hypothetical protein ECs0849 1 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830953 Common - putative ATP-binding protein of ABC transporter ECs1699 43 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15829627 Common - deaminase ECs0373 66 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15830376 Common - putative outer membrane protein ECs1122 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15832694 Common - L-aspartate oxidase ECs3440 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 15829640 Common - methylcitrate synthase ECs0386 194 COG0372 GltA, Citrate synthase Energy production and conversion 15829565 Common - putative transport protein ECs0311 146 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 162139739 Common - 2-keto-3-deoxygluconate permease ECs4835 27 None None None 15830335 Pathogen - hypothetical protein ECs1081 5 None None None 15829777 Common - DNA polymerase III subunits gamma and tau ECs0523 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15829499 Common - putative H repeat-associated protein ECs0245 32 COG5433 COG5433, Transposase DNA replication, recombination, and repair 15834282 Common - putative stress-response protein ECs5028 56 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 38703957 Common - hypothetical protein ECs5432 6 None None None 15832207 Pathogen - putative minor tail protein U ECs2953 4 None None None 38703884 Common - citrate lyase synthetase (citrate (pro-3S)-lyase ligase ECs0657 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 15830223 Common infA translation initiation factor IF-1 ECs0969 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 15833381 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit ECs4127 197 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 15830519 Common - hypothetical protein ECs1265 38 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 15829330 Common - isopropylmalate isomerase large subunit ECs0076 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 15830996 Common - hypothetical protein ECs1742 159 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 15833398 Common - putative ATP-binding component of a transport system ECs4144 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15834445 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein ECs5191 127 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 15833079 Common - Holliday junction resolvase-like protein ECs3825 185 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 15832085 Common - acetyltransferase ECs2831 74 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15832231 Common - hypothetical protein ECs2977 12 None None None 15833373 Common - ribonuclease G ECs4119 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 15830910 Common - hypothetical protein ECs1656 11 None None None 15830868 Common emrE multidrug efflux protein ECs1614 135 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 15829590 Common - putative invasin ECs0336 84 None None None 38704209 Common - phosphatase ECs4808 70 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 38704245 Common - peptidyl-prolyl cis-trans isomerase ECs5185 146 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 15830020 Pathogen - hypothetical protein ECs0766 1 None None None 15833629 Common - arsenate reductase ECs4375 111 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 15829746 Common clpX ATP-dependent protease ATP-binding subunit ECs0492 233 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 15831613 Common - N-ethylmaleimide reductase, FMN-linked ECs2359 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15832664 Common - hypothetical protein ECs3410 37 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 15831296 Common - hypothetical protein ECs2042 19 COG1598 COG1598, Uncharacterized conserved protein Function unknown 15831313 Common - hypothetical protein ECs2059 2 None None None 15833193 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase ECs3939 194 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15834084 Common - L-rhamnose isomerase ECs4830 23 COG4806 RhaA, L-rhamnose isomerase Carbohydrate transport and metabolism 15833634 Common - heme utilization/transport protein ECs4380 106 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 15829369 Common - regulatory protein AmpE ECs0115 17 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 15831015 Common - DicB ECs1761 1 None None None 15833564 Common - RNA polymerase factor sigma-32 ECs4310 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15831737 Common - putative oxidoreductase ECs2483 213 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15832524 Common - hypothetical protein ECs3270 9 None None None 15831133 Common - GABA aminotransferase, PLP-dependent ECs1879 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 15830524 Common - predicted outer membrane protein ECs1270 18 None None None 15830627 Common - InsA ECs1373 13 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830885 Pathogen - head-to-tail joining protein ECs1631 4 None None None 15831790 Common - hypothetical protein ECs2536 5 None None None 15834224 Common - hypothetical protein ECs4970 26 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 15829926 Common - cell wall shape-determining protein ECs0672 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15830809 Common - putative minor tail protein ECs1555 14 COG4672 gp18, Phage-related protein Function unknown 162139814 Common cdsA CDP-diglyceride synthase ECs0177 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 15831689 Common - part of a kinase ECs2435 154 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 15830929 Common - predicted isomerase/hydrolase ECs1675 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 162139821 Common - DNA-binding transcriptional activator CaiF ECs0037 4 None None None 38704028 Common - hypothetical protein ECs2585 20 COG3102 COG3102, Uncharacterized protein conserved in bacteria Function unknown 15832969 Common - hypothetical protein ECs3715 6 None None None 15831781 Common - mannose-specific PTS enzyme IIAB ECs2527 88 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 15834589 Common - hypothetical protein ECs5335 45 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 15829343 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase ECs0089 207 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15831805 Common - hypothetical protein ECs2551 23 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 15831217 Common - hypothetical protein ECs1963 2 None None None 38703870 Common - glycoprotein/polysaccharide metabolism ECs0507 30 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 15830772 Common - hypothetical protein ECs1518 4 None None None 15833434 Common rplV 50S ribosomal protein L22 ECs4180 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 15832459 Common - predicted flagella assembly protein ECs3205 10 None None None 15830234 Common - anaerobic dimethyl sulfoxide reductase subunit B ECs0980 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15831505 Common - putative terminase large subunit ECs2251 35 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 15832898 Common relA GDP/GTP pyrophosphokinase ECs3644 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 15832874 Common - putative 6-pyruvoyl tetrahydrobiopterin synthase ECs3620 127 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15831657 Common - putative ARAC-type regulatory protein ECs2403 112 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15830649 Common - hypothetical protein ECs1395 45 COG3596 COG3596, Predicted GTPase General function prediction only 15830842 Pathogen - putative transcriptional activator ECs1588 1 None None None 15829316 Common - 23S rRNA/tRNA pseudouridine synthase A ECs0062 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15831169 Common - fumarate/nitrate reduction transcriptional regulator ECs1915 159 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15830635 Common - putative transposase ECs1381 33 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830981 Common - nitrate/nitrite sensor protein NarX ECs1727 148 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 15830337 Common - putative crossover junction endodeoxyribonuclease ECs1083 7 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 15831493 Common - putative minor tail protein ECs2239 7 COG4718 COG4718, Phage-related protein Function unknown 15832793 Common nrdF ribonucleotide-diphosphate reductase subunit beta ECs3539 140 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 15833461 Common - hypothetical protein ECs4207 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15834369 Common - DNA-binding transcriptional activator ECs5115 86 COG3710 CadC, DNA-binding winged-HTH domains Transcription 15834002 Pathogen - hypothetical membrane protein ECs4748 2 None None None 15831949 Common - hypothetical protein ECs2695 5 COG5475 COG5475, Uncharacterized small protein Function unknown 15832482 Common - hypothetical protein ECs3228 2 None None None 15830726 Common acpP acyl carrier protein ECs1472 182 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15831463 Common - putative repressor protein ECs2209 7 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15829634 Common - hypothetical protein ECs0380 2 None None None 15832495 Common lacY galactoside permease ECs3241 20 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 38704230 Common - hypothetical protein ECs5042 7 None None None 15830275 Common - putative fimbrial-like protein ECs1021 21 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832334 Common - putative sulfatase ECs3080 30 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 15833422 Common rpsE 30S ribosomal protein S5 ECs4168 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 15833907 Common - hypothetical protein ECs4653 5 None None None 15833872 Common - hypothetical protein ECs4618 3 None None None 15830443 Common - replication protein O ECs1189 7 None None None 15832080 Common - imidazole glycerol phosphate synthase subunit HisF ECs2826 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 15830552 Common - hypothetical protein ECs1298 2 None None None 15832637 Common - putative anaerobic dimethyl sulfoxide reductase chain B ECs3383 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15834542 Common - hypothetical protein ECs5288 11 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 15832304 Common - hypothetical protein ECs3050 111 COG2855 COG2855, Predicted membrane protein Function unknown 15831473 Common - putative transposase ECs2219 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834510 Common - hypothetical protein ECs5256 4 COG1403 McrA, Restriction endonuclease Defense mechanisms 15830800 Common - putative head-tail adapotor ECs1546 3 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 15834373 Common - anaerobic C4-dicarboxylate transporter ECs5119 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 15832466 Common mepA penicillin-insensitive murein endopeptidase ECs3212 39 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 15834029 Common - proline dipeptidase ECs4775 183 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15834209 Pathogen - hypothetical protein ECs4955 2 None None None 15834216 Common - putative endolysin ECs4962 31 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15833717 Common - hypothetical protein ECs4463 16 None None None 15832409 Common - hypothetical protein ECs3155 81 COG2153 ElaA, Predicted acyltransferase General function prediction only 15831406 Common - putative transport protein ECs2152 160 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15831485 Common - putative tail fiber protein ECs2231 4 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15834009 Common - lysophospholipase L2 ECs4755 74 COG2267 PldB, Lysophospholipase Lipid metabolism 15830033 Common - PnuC ECs0779 62 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 15832166 Common - nickel/cobalt efflux protein RcnA ECs2912 31 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 15832835 Common - transcriptional repressor of hyc and hyp operons ECs3581 7 None None None 15832107 Common - phosphomannomutase ECs2853 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15829606 Common - hypothetical protein ECs0352 1 None None None 15829880 Common - ferric enterobactin (enterochelin) transport ECs0626 18 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 15833167 Common - putative ferrichrome-binding protein ECs3913 43 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15831381 Common - hypothetical protein ECs2127 56 COG3781 COG3781, Predicted membrane protein Function unknown 15834351 Common - arginine:agmatin antiporter ECs5097 180 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15830015 Common - 3-methylaspartate ammonia-lyase ECs0761 15 COG3799 Mal, Methylaspartate ammonia-lyase Amino acid transport and metabolism 15832913 Common - L-1,2-propanediol oxidoreductase ECs3659 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 15829894 Common - hypothetical protein ECs0640 17 COG1475 Spo0J, Predicted transcriptional regulators Transcription 15829587 Common - putative transcriptional regulator ECs0333 169 COG0583 LysR, Transcriptional regulator Transcription 15830753 Common potD spermidine/putrescine ABC transporter periplasmic substrate-binding protein ECs1499 140 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15831653 Common aroE quinate/shikimate dehydrogenase ECs2399 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 15832567 Common - reactivating factor for ethanolamine ammonia lyase ECs3313 17 COG4819 EutA, Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition Amino acid transport and metabolism 15832037 Common cbl transcriptional regulator Cbl ECs2783 191 COG0583 LysR, Transcriptional regulator Transcription 15830853 Pathogen - hypothetical protein ECs1599 2 None None None 15832295 Common - galactose/methyl galaxtoside transporter ATP-binding protein ECs3041 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15833082 Common - putative resistance protein ECs3828 74 COG0762 COG0762, Predicted integral membrane protein Function unknown 15832750 Common - hypothetical protein ECs3496 3 None None None 38704114 Common - hypothetical protein ECs3533 16 COG4575 ElaB, Uncharacterized conserved protein Function unknown 15830111 Common - excinuclease ABC subunit B ECs0857 230 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 15834157 Common tuf elongation factor Tu ECs4903 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15833924 Common - putative type 1 fimbrial protein ECs4670 20 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832922 Common - DNA-binding transcriptional activator GcvA ECs3668 190 COG0583 LysR, Transcriptional regulator Transcription 162139732 Common - glycerol-3-phosphate acyltransferase ECs5024 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 15831626 Common - multidrug efflux protein ECs2372 166 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15832885 Common - putative transport protein ECs3631 19 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 162139760 Common - hypothetical protein ECs3829 66 COG1872 COG1872, Uncharacterized conserved protein Function unknown 15831981 Pathogen - putative minor tail protein ECs2727 2 None None None 38704226 Common ubiC chorismate pyruvate lyase ECs5022 18 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 15829354 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase ECs0100 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 15833556 Common livG leucine/isoleucine/valine transporter ATP-binding subunit ECs4302 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 15833764 Common - formamidopyrimidine-DNA glycosylase ECs4510 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 15832351 Common - ferredoxin-type protein ECs3097 57 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15832241 Common - phage replication protein O ECs2987 9 None None None 15831066 Pathogen - hypothetical protein ECs1812 1 None None None 15829515 Common - hypothetical protein ECs0261 48 COG3153 COG3153, Predicted acetyltransferase General function prediction only 15831009 Common - hypothetical protein ECs1755 15 None None None 15829686 Common - hypothetical protein ECs0432 6 None None None 15829864 Common - copper/silver efflux system outer membrane protein CusC ECs0610 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15829910 Common - citrate lyase subunit gamma ECs0656 25 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 15830463 Common - putative transposase ECs1209 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829889 Common - 2,3-dihydroxybenzoate-2,3-dehydrogenase ECs0635 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15834034 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A ECs4780 135 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 15832479 Common fadI 3-ketoacyl-CoA thiolase ECs3225 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 15832775 Common - hypothetical protein ECs3521 119 COG0579 COG0579, Predicted dehydrogenase General function prediction only 15833103 Common - hypothetical protein ECs3849 17 COG3972 COG3972, Superfamily I DNA and RNA helicases General function prediction only 15833530 Common - glycogen debranching enzyme ECs4276 152 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 15831889 Pathogen - putative plasmid partition protein ECs2635 3 None None None 15832358 Common - outer membrane porin protein C ECs3104 24 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15832952 Common - low-affinity L-arabinose transport system proton symport protein ECs3698 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15831363 Common - putative fimbrial-like protein ECs2109 23 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832401 Common - polymyxin resistance protein B ECs3147 4 None None None 15831958 Pathogen - hypothetical protein ECs2704 1 None None None 38703997 Pathogen - hypothetical protein ECs5457 3 None None None 15834232 Common - hypothetical protein ECs4978 3 None None None 15830406 Common - trimethylamine N-oxide reductase subunit ECs1152 166 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15834399 Common - N-acetylmuramoyl-l-alanine amidase II ECs5145 165 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15830065 Common - NinF ECs0811 3 None None None 15833891 Common dnaA chromosomal replication initiation protein ECs4637 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15830936 Common - fatty acid metabolism regulator ECs1682 62 COG2186 FadR, Transcriptional regulators Transcription 162139791 Common - twin-argninine leader-binding protein DmsD ECs2297 27 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 15832161 Common - hydroxyethylthiazole kinase ECs2907 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 162139747 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase ECs4514 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 15833886 Common - predicted hydrolase ECs4632 142 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15834248 Pathogen - hypothetical protein ECs4994 1 None None None 15830049 Common - 6-phosphogluconolactonase ECs0795 52 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 15829887 Common entE enterobactin synthase subunit E ECs0633 222 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 38703854 Common - putative transporter ECs0346 70 COG1556 COG1556, Uncharacterized conserved protein Function unknown 15831776 Common - hypothetical protein ECs2522 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 162139800 Common - fatty acid/phospholipid synthesis protein ECs1468 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 15831210 Common - hypothetical protein ECs1956 11 None None None 15830821 Pathogen - hypothetical protein ECs1567 2 None None None 15834203 Common - hypothetical protein ECs4949 5 None None None 15832667 Common - putative ATP-binding component of a transport system ECs3413 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15833782 Pathogen - hypothetical protein ECs4528 2 None None None 15831321 Common - hypothetical protein ECs2067 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 15831700 Common nadE NAD synthetase ECs2446 136 COG0171 NadE, NAD synthase Coenzyme metabolism 15830093 Common - putative minor tail protein ECs0839 14 COG4672 gp18, Phage-related protein Function unknown 15832619 Common - putative cytochrome C-type biogenesis protein ECs3365 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15831606 Common - hypothetical protein ECs2352 9 None None None 162139796 Common - putative oxidoreductase ECs1860 10 COG4950 COG4950, Uncharacterized protein conserved in bacteria Function unknown 15831840 Common argS arginyl-tRNA synthetase ECs2586 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 38703977 Common - hypothetical protein ECs2038 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 15830640 Common - hypothetical protein ECs1386 18 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 15831730 Common - putative transport protein ECs2476 160 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15832273 Common - beta-D-glucoside glucohydrolase ECs3019 129 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 15830453 Common - putative antirepressor protein ECs1199 10 COG3561 COG3561, Phage anti-repressor protein Transcription 38703984 Common - hypothetical protein ECs5443 169 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15833306 Common - argininosuccinate synthase ECs4052 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 15830686 Common - lipid A biosynthesis lauroyl acyltransferase ECs1432 102 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 15831099 Common - hypothetical protein ECs1845 13 None None None 15834598 Pathogen - hypothetical protein ECs5344 2 None None None 15829283 Common ileS isoleucyl-tRNA synthetase ECs0029 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15830128 Common - putative DNA-binding transcriptional regulator ECs0874 20 COG1309 AcrR, Transcriptional regulator Transcription 15830132 Common - hypothetical protein ECs0878 152 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 15832927 Common mltA murein transglycosylase A ECs3673 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 15832534 Common - hypothetical protein ECs3280 11 COG0583 LysR, Transcriptional regulator Transcription 15832260 Common - putative C4-type zinc finger protein ECs3006 10 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15829815 Pathogen - hypothetical protein ECs0561 2 None None None 15832433 Common - hypothetical protein ECs3179 19 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 15832560 Common - N-acetylmuramoyl-l-alanine amidase I ECs3306 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15833133 Common - hydrogenase 2 large subunit ECs3879 108 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 15832541 Common - phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr) ECs3287 138 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 15831428 Common - putative major capsid protein ECs2174 10 None None None 15831224 Common - putative terminase small subunit ECs1970 4 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 15831867 Common - ferritin ECs2613 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 15829798 Common - putative membrane fusion protein of a transport system ECs0544 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15829485 Common - hypothetical protein ECs0231 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 38703967 Common - hypothetical protein ECs5433 3 None None None 15832422 Common - NADH dehydrogenase I subunit F ECs3168 168 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 15829530 Common - cII ECs0276 4 None None None 15830504 Common - C4-type zinc finger protein (TraR family) ECs1250 8 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15832165 Common - hypothetical protein ECs2911 75 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 15833471 Common nirD nitrite reductase small subunit ECs4217 45 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 15832076 Common - histidinol-phosphate aminotransferase ECs2822 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 15831462 Common - putative regulatory protein ECs2208 4 None None None 15831192 Common - hypothetical protein ECs1939 4 None None None 15833707 Common - hypothetical protein ECs4453 31 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 38703955 Common - hypothetical protein ECs1831 12 None None None 15831615 Common - ribonuclease T ECs2361 59 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 162139782 Common fliH flagellar assembly protein H ECs2679 46 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15830669 Common - curli assembly protein CsgF ECs1415 9 None None None 15833158 Common - putative binding protein ECs3904 204 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15829771 Common - DNA-binding transcriptional repressor ECs0517 135 COG1309 AcrR, Transcriptional regulator Transcription 15831120 Common - putative membrane transport protein ECs1866 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 38704190 Common - putative transporter ECs4533 83 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15829871 Common - hypothetical protein ECs0617 37 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 15834110 Common - ribonuclease activity regulator protein RraA ECs4856 67 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 38703919 Common - hypothetical protein ECs1258 77 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 15829660 Common - acetaldehyde dehydrogenase ECs0406 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 15831881 Pathogen - hypothetical protein ECs2627 1 None None None 38704183 Common - hypothetical protein ECs4492 65 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 15831088 Common - bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase ECs1834 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 15833602 Common - nickel responsive regulator ECs4348 60 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 15833977 Common - TDP-fucosamine acetyltransferase ECs4723 14 None None None 15830420 Pathogen - hypothetical protein ECs1166 2 None None None 15829684 Common - hypothetical protein ECs0430 6 None None None 15834385 Common ampC beta-lactamase ECs5131 121 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 15830241 Common - formate transporter ECs0987 92 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 15834464 Common - putative ligase ECs5210 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 15831517 Pathogen - hypothetical protein ECs2263 1 None None None 15831857 Common - universal stress protein UspC ECs2603 30 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15834501 Pathogen - hypothetical protein ECs5247 1 None None None 15830901 Common - tail assembly protein ECs1647 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 38704217 Common - pyruvate formate lyase II activase ECs4881 62 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15833869 Common - putative transcriptional regulator ECs4615 11 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 15833544 Common - putative acetyltransferase YhhY ECs4290 78 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15832553 Common murQ N-acetylmuramic acid-6-phosphate etherase ECs3299 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 15829917 Common ccrB camphor resistance protein CrcB ECs0663 188 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 15833572 Common zntA zinc/cadmium/mercury/lead-transporting ATPase ECs4318 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15833910 Pathogen - hypothetical protein ECs4656 1 None None None 15830270 Common ssuB aliphatic sulfonates transport ATP-binding subunit ECs1016 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 15831708 Common argD bifunctional succinylornithine transaminase/acetylornithine transaminase ECs2454 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 15829720 Common - hypothetical protein ECs0466 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 15832507 Common - putative oxalyl-CoA decarboxylase ECs3253 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15830009 Common - putative transcription regulator ECs0755 156 COG0583 LysR, Transcriptional regulator Transcription 15829452 Common rcsF outer membrane lipoprotein ECs0198 13 None None None 15831918 Common fliS flagellar protein FliS ECs2664 84 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15834488 Common - hypothetical protein ECs5234 29 COG4269 COG4269, Predicted membrane protein Function unknown 15833984 Common - putative arylsulfatase regulator ECs4730 93 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 15830174 Common - DNA-binding transcriptional repressor ECs0920 111 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 162139773 Common - ribonuclease Z ECs3156 133 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 15829955 Pathogen - hypothetical protein ECs0701 6 None None None 15830450 Common - putative DNA methylase ECs1196 10 None None None 15830545 Common - hypothetical protein ECs1291 2 None None None 15834508 Common - hypothetical protein ECs5254 27 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 15834325 Common - putative carbohydrate binding protein ECs5071 99 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15834334 Common phnK phosphonates transport ATP-binding protein ECs5080 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 15830151 Common - putative ATP-binding component of a transport system ECs0897 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 38704154 Common panF sodium/panthothenate symporter ECs4130 175 COG4145 PanF, Na+/panthothenate symporter Coenzyme metabolism 15832629 Common - hypothetical protein ECs3375 60 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 15833917 Common pstC phosphate transporter permease subunit ECs4663 225 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 15831640 Common - cysteine desufuration protein SufE ECs2386 93 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 15830973 Common - putative transcriptional regulator ECs1719 51 COG2912 COG2912, Uncharacterized conserved protein Function unknown 162139746 Common dinD DNA-damage-inducible protein D ECs4520 21 None None None 15829549 Common - hypothetical protein ECs0295 10 None None None 15829447 Common - hypothetical protein ECs0193 119 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 38704133 Common - ornithine decarboxylase isozyme ECs3841 84 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 15832090 Common - mannose-1-P guanosyltransferase ECs2836 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 15830694 Common - dihydroorotase ECs1440 86 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 15832139 Common - multidrug efflux system protein MdtE ECs2885 192 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15833504 Common feoA ferrous iron transport protein A ECs4250 33 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 15830835 Pathogen - hypothetical protein ECs1581 2 None None None 15831992 Common - putative endopeptidase ECs2739 9 None None None 15829333 Common - leu operon leader peptide ECs0079 2 None None None 15830422 Pathogen - hypothetical protein ECs1168 1 None None None 15833022 Common - hypothetical protein ECs3768 11 None None None 162139819 Common leuO leucine transcriptional activator ECs0080 115 COG0583 LysR, Transcriptional regulator Transcription 15832255 Common - Bet ECs3001 11 None None None 162139729 Common - DNA-binding transcriptional activator BglJ ECs5326 32 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15833429 Common rplN 50S ribosomal protein L14 ECs4175 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 38703907 Common - putative oxidoreductase ECs1051 142 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 15834117 Common rpmE 50S ribosomal protein L31 ECs4863 182 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15832946 Common - hypothetical protein ECs3692 74 None None None 15833848 Common - putative permease transporter ECs4594 52 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 15833943 Common trkD potassium transport protein Kup ECs4689 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 15831255 Common - heat-inducible protein ECs2001 13 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 15831854 Common - flagellar motor protein MotA ECs2600 121 COG1291 MotA, Flagellar motor component Cell motility and secretion 15832974 Common - putative transcriptional regulator ECs3720 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15832212 Common - putative transposase ECs2958 31 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832620 Common - hypothetical protein ECs3366 6 None None None 15830208 Common - putative nucleotide di-P-sugar epimerase or dehydratase ECs0954 126 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15832052 Pathogen - hypothetical protein ECs2798 3 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 38704053 Common - putative two-component response-regulatory protein YehT ECs2936 211 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 15834082 Common - hypothetical protein ECs4828 39 COG3254 COG3254, Uncharacterized conserved protein Function unknown 15831696 Common - N,N'-diacetylchitobiose-specific PTS system transporter subunit IIA ECs2442 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 15829604 Common - putative adhesin ECs0350 16 None None None 15830205 Pathogen - hypothetical protein ECs0951 1 None None None 15833151 Common - hypothetical protein ECs3897 2 None None None 15829373 Common aceF dihydrolipoamide acetyltransferase ECs0119 197 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 15833492 Common mrcA peptidoglycan synthetase ECs4238 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 15830158 Common - molybdopterin biosynthesis protein MoeB ECs0904 217 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 38704099 Common - aminopeptidase B ECs3389 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 15832869 Common - hypothetical protein ECs3615 78 COG1203 COG1203, Predicted helicases General function prediction only 15832193 Common - hypothetical protein ECs2939 11 None None None 15829995 Common - hypothetical protein ECs0741 9 None None None 38703900 Common - hydroxylamine reductase ECs0959 76 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 15833963 Common - peptidyl-prolyl cis-trans isomerase C ECs4709 142 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15830732 Common - predicted metallodependent hydrolase ECs1478 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15829471 Common - hypothetical protein ECs0217 11 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 15832246 Pathogen - hypothetical protein ECs2992 2 None None None 15832386 Common - putative transposase ECs3132 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 38704232 Common - hypothetical protein ECs5584 3 None None None 15831328 Common - hypothetical protein ECs2074 2 None None None 15831546 Common - hypothetical protein ECs2292 11 None None None 15831300 Common - putative transport system permease protein ECs2046 214 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 15832851 Common pcm protein-L-isoaspartate O-methyltransferase ECs3597 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 15831185 Common - hypothetical protein ECs1931 3 None None None 15830435 Pathogen - N ECs1181 2 None None None 15832746 Common - hypothetical protein ECs3492 13 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 38703868 Common - transcriptional regulator BolA ECs0489 105 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 15833862 Pathogen - hypothetical protein ECs4608 1 None None None 15834047 Common - GTP-binding protein ECs4793 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 15832205 Pathogen - putative minor tail protein ECs2951 3 None None None 38703964 Common - putative transport periplasmic protein ECs1911 200 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15833595 Common - 3-oxoacyl-(acyl carrier protein) synthase II ECs4341 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15832931 Common RecB exonuclease V subunit beta ECs3677 220 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 38704120 Common - putative amidase ECs3674 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15833921 Common - putative outer membrane usher protein precursor ECs4667 28 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 38703893 Common - putative ATP-binding component of a transport system ECs0872 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15833496 Common - ribosome-associated heat shock protein Hsp15 ECs4242 107 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 15830950 Common - hypothetical protein ECs1696 26 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 15834108 Pathogen - hypothetical protein ECs4854 2 None None None 15831528 Pathogen - hypothetical protein ECs2274 3 None None None 15831491 Common - putative tail assembly protein ECs2237 14 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 162139789 Pathogen - acid shock protein precursor ECs2303 1 None None None 15831499 Common - hypothetical protein ECs2245 5 None None None 15829938 Common - hypothetical protein of polynucleotide modification ECs0684 7 COG5407 SEC63, Preprotein translocase subunit Sec63 Intracellular trafficking and secretion 15830083 Common - putative protease/scaffold protein ECs0829 158 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15831012 Common - excisionase ECs1758 4 None None None 15831445 Common - putative transcriptional regulator ECs2191 24 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15829895 Common - hypothetical protein ECs0641 18 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 15831437 Common - putative endopeptidase ECs2184 9 None None None 15833073 Common - galactose-proton symport of transport system ECs3819 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830678 Common - putative synthase ECs1424 147 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15834480 Common - oxidoreductase ECs5226 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15830005 Common kgd alpha-ketoglutarate decarboxylase ECs0751 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 15834249 Pathogen - hypothetical protein ECs4995 1 None None None 15830514 Common putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase ECs1260 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 15833604 Common - putative phosphotransferase system enzyme IIA ECs4350 20 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15830863 Common - intergrase ECs1609 21 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15831329 Pathogen - IpaH-like protein ECs2075 2 None None None 15829781 Common adk adenylate kinase ECs0527 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 15830224 Common aat leucyl/phenylalanyl-tRNA--protein transferase ECs0970 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 15832671 Common glyA serine hydroxymethyltransferase ECs3417 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 38703867 Common - hypothetical protein ECs0488 19 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 15834614 Common - hypothetical protein ECs5360 4 None None None 15831845 Common - chemotaxis regulator CheZ ECs2591 42 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15834408 Common - transcriptional repressor NsrR ECs5154 159 COG1959 COG1959, Predicted transcriptional regulator Transcription 15831580 Common - repressor for uid operon ECs2326 120 COG1309 AcrR, Transcriptional regulator Transcription 15831175 Common - hypothetical protein ECs1921 89 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 15829787 Common ushA bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ECs0533 139 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 15833404 Common - hypothetical protein ECs4150 40 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 15831687 Common - predicted hydrolase ECs2433 170 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15830663 Common - hypothetical protein ECs1409 13 None None None 15831566 Common - short chain dehydrogenase ECs2312 133 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 38703860 Common - 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase ECs0404 130 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15834307 Common - cytochrome c-type protein NrfB ECs5053 18 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 15831531 Common - hypothetical protein ECs2277 5 None None None 15832950 Common - DNA-binding transcriptional regulator LysR ECs3696 176 COG0583 LysR, Transcriptional regulator Transcription 15829616 Common - AidA-I adhesin-like protein ECs0362 63 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 38704199 Pathogen - hypothetical protein ECs5542 1 None None None 162139761 Common - acetyl-CoA acetyltransferase ECs3701 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 15832276 Common - hypothetical protein ECs3022 24 None None None 15834175 Common - endonuclease V ECs4921 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 15833031 Common - hypothetical protein ECs3777 134 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 38703934 Common - hypothetical protein ECs1486 21 COG3150 COG3150, Predicted esterase General function prediction only 15832299 Common folE GTP cyclohydrolase I ECs3045 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 15833788 Common - putative integrase ECs4534 117 COG0582 XerC, Integrase DNA replication, recombination, and repair 15829850 Common - predicted fimbrial-like adhesin protein ECs0596 22 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15830101 Pathogen - hypothetical protein ECs0847 1 None None None 15833566 Common - cell division protein FtsE ECs4312 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 15829351 Common - cell division protein FtsQ ECs0097 73 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 15833839 Pathogen - hypothetical protein ECs4585 1 None None None 15829404 Common - sugar fermentation stimulation protein A ECs0150 108 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 15829725 Common - phosphatidylglycerophosphatase A ECs0471 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 15833594 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase ECs4340 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15829756 Common - putative multidrug transporter membrane\ATP-binding components ECs0502 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15833636 Common - putative hemin binding protein ECs4382 153 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 15831256 Common - D-lactate dehydrogenase ECs2002 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15829367 Common - quinolinate phosphoribosyltransferase ECs0113 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 15832788 Common - putative transcriptional regulator ECs3534 195 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 15830530 Common - putative chaperone protein ECs1276 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15833244 Common - hypothetical protein ECs3990 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 15832934 Common - hypothetical protein ECs3680 6 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 15831420 Common - putative tail length tape measure protein precursor ECs2166 17 COG5281 COG5281, Phage-related minor tail protein Function unknown 15830378 Pathogen - hypothetical protein ECs1124 1 None None None 15832857 Common - hypothetical protein ECs3603 10 None None None 162139737 Common cpxP periplasmic repressor CpxP ECs4839 17 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 15831150 Common - putative beta-phosphoglucomutase ECs1896 167 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 38704227 Common - zinc uptake transcriptional repressor ECs5029 135 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15830235 Common - anaerobic dimethyl sulfoxide reductase subunit C ECs0981 21 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 15830360 Common - putative terminase large subunit ECs1106 36 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 15830380 Pathogen - hypothetical protein ECs1125 1 None None None 15829423 Common - PII uridylyl-transferase ECs0169 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 15829554 Common - putative CI repressor ECs0300 7 None None None 15830026 Common - colicin uptake protein TolQ ECs0772 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15834410 Common - 23S rRNA (guanosine-2'-O-)-methyltransferase ECs5156 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15829494 Pathogen - hypothetical protein ECs0240 1 None None None 15832574 Common eutD phosphotransacetylase ECs3320 165 COG0280 Pta, Phosphotransacetylase Energy production and conversion 15829465 Common - DNA polymerase III subunit epsilon ECs0211 182 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15830634 Common - putative transposase ECs1380 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833966 Common - guanosine pentaphosphate phosphohydrolase ECs4712 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 15834055 Common - hypothetical membrane protein ECs4801 68 COG0730 COG0730, Predicted permeases General function prediction only 162139709 Common bssS biofilm formation regulatory protein BssS ECs1438 11 None None None 15831538 Common - inhibitor of cell division ECs2284 1 None None None 15831879 Pathogen - hypothetical protein ECs2625 2 None None None 15831746 Common - hypothetical protein ECs2492 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 15830175 Common - undecaprenyl pyrophosphate phosphatase ECs0921 67 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 38704083 Common - hypothetical protein ECs3302 50 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 38704032 Common - putative tail protein ECs2639 27 COG3499 COG3499, Phage protein U General function prediction only 15832580 Common - transaldolase A ECs3326 188 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15829940 Common - putative tRNA ligase ECs0686 8 None None None 15830141 Common glnQ glutamine ABC transporter ATP-binding protein ECs0887 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15831645 Common sufA iron-sulfur cluster assembly scaffold protein ECs2391 161 COG0316 IscA, Uncharacterized conserved protein Function unknown 15831587 Common - beta-lactam resistance protein ECs2333 3 None None None 15832303 Common - putative DNA-binding transcriptional regulator ECs3049 187 COG0583 LysR, Transcriptional regulator Transcription 15830148 Common - manganese transport regulator MntR ECs0894 91 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 15833916 Common pstA phosphate transporter permease subunit ECs4662 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 15831764 Common - putative transporter ECs2510 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 15832587 Common - hypothetical protein ECs3333 101 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 15830257 Common - hypothetical protein ECs1003 74 COG1434 COG1434, Uncharacterized conserved protein Function unknown 15829295 Common - crotonobetainyl-CoA:carnitine CoA-transferase ECs0041 111 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 15832829 Common - formate hydrogenlyase subunit-7 component G ECs3575 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 15832970 Common - EprK ECs3716 27 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 162139780 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase ECs2825 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 15830961 Common - hypothetical protein ECs1707 47 None None None 15834348 Common - sensor protein BasS/PmrB ECs5094 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15831570 Common - DNA replication terminus site-binding protein ECs2316 14 None None None 15833955 Pathogen - ilvG operon leader peptide ECs4701 1 None None None 15832091 Common - putative GDP-L-fucose pathway enzyme ECs2837 18 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15833645 Common - acid-resistance membrane protein ECs4391 16 COG3247 HdeD, Uncharacterized conserved protein Function unknown 15830168 Pathogen - hypothetical protein ECs0914 1 None None None 15833237 Common - hypothetical protein ECs3983 35 COG2259 COG2259, Predicted membrane protein Function unknown 15831713 Common - hypothetical protein ECs2459 31 COG2128 COG2128, Uncharacterized conserved protein Function unknown 15833186 Common - putative oxidoreductase ECs3932 10 None None None 38704181 Common - hypothetical protein ECs4445 13 COG4682 COG4682, Predicted membrane protein Function unknown 15830229 Common - DNA translocase FtsK ECs0975 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15830036 Common - phospho-2-dehydro-3-heoxyheptonate aldolase ECs0782 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 15832449 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ECs3195 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 15834599 Common - lipoate-protein ligase A ECs5345 79 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 15833906 Common - predicted hydrolase ECs4652 143 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15832862 Common - hypothetical protein ECs3608 29 None None None 15832942 Common - DNA mismatch repair protein ECs3688 28 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 15834567 Common - putative carbon starvation protein ECs5313 105 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 15832234 Common - NinE ECs2980 2 None None None 15833716 Common - hypothetical protein ECs4462 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 38704016 Common - hypothetical protein ECs2486 28 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 15833033 Common - proline aminopeptidase P II ECs3779 245 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15833134 Common - predicted hydrogenase 2 cytochrome b type component ECs3880 30 COG5557 COG5557, Polysulphide reductase Energy production and conversion 15833147 Common - hypothetical protein ECs3893 95 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15829925 Common - rare lipoprotein A ECs0671 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 15832460 Common - hypothetical protein ECs3206 29 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15830387 Common - HyaF ECs1133 19 None None None 15832609 Common - putative permease ECs3355 136 COG0628 PerM, Predicted permease General function prediction only 15830120 Common - hypothetical protein ECs0866 56 COG0392 COG0392, Predicted integral membrane protein Function unknown 15831383 Common - hypothetical protein ECs2129 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15832962 Common - hypothetical protein ECs3708 12 None None None 15833064 Common - transketolase ECs3810 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15830577 Common ureB urease subunit beta ECs1323 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 15834605 Common - Trp operon repressor ECs5351 22 COG2973 TrpR, Trp operon repressor Transcription 15833579 Common - putative O-methyltransferase ECs4325 30 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15833583 Common - acyl carrier protein ECs4329 70 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15831934 Common fliI flagellum-specific ATP synthase ECs2680 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 15829774 Common - primosomal replication protein N'' ECs0520 14 COG3923 PriC, Primosomal replication protein N'' DNA replication, recombination, and repair 38703926 Common - hypothetical protein ECs5414 6 COG3311 AlpA, Predicted transcriptional regulator Transcription 15833693 Common - hypothetical protein ECs4439 12 None None None 15834332 Common - PhnM ECs5078 52 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 15834548 Common - hypothetical protein ECs5294 9 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 15831073 Common - hypothetical protein ECs1819 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829813 Common - putative oxidoreductase ECs0559 88 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 15829285 Common - putative FKBX-type 16KD peptidyl-prolyl cis-trans isomerase ECs0031 130 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 15832527 Common - hypothetical protein ECs3273 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15834081 Common - putative glycoprotein ECs4827 11 None None None 15831751 Common - hypothetical protein ECs2497 2 None None None 15830609 Common - TerD ECs1355 30 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 38704170 Common - hypothetical protein ECs4323 194 COG0628 PerM, Predicted permease General function prediction only 15830600 Common - hypothetical protein ECs1346 24 None None None 15829835 Common - hypothetical protein ECs0581 17 None None None 15831059 Common - minor tail protein ECs1805 14 COG4672 gp18, Phage-related protein Function unknown 15834193 Common - peptidase E ECs4939 35 COG3340 PepE, Peptidase E Amino acid transport and metabolism 15832730 Common - heat shock protein GrpE ECs3476 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15831732 Common - putative transposase ECs2478 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834261 Common - aspartate kinase III ECs5007 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15830771 Pathogen - hypothetical protein ECs1517 1 None None None 15831515 Common - putative holin protein ECs2261 5 None None None 15832057 Common - putative DNA repair protein ECs2803 173 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 15834295 Common - single-strand DNA-binding protein ECs5041 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15833613 Common - putative ATP-binding component of a transport system ECs4359 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15831665 Common - phospho-2-dehydro-3-deoxyheptonate aldolase ECs2411 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 15829638 Common - regulator for prp operon ECs0384 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 15829470 Common - Hcp-like protein ECs0216 21 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 15833323 Common - hypothetical protein ECs4069 72 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 15832737 Common - putative DNA damage-inducible protein ECs3483 11 None None None 15829322 Common - DNA-binding transcriptional regulator AraC ECs0068 128 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15833266 Common - N-acetylgalactosamine-specific PTS system enzyme IIC component ECs4012 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 15829668 Common - putative ferric transport system permease ECs0414 221 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 38703945 Common - hypothetical protein ECs5421 3 None None None 15830354 Common - putative holin protein ECs1100 5 None None None 15833795 Pathogen - hypothetical protein ECs4541 3 None None None 15830912 Common - hypothetical protein ECs1658 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831237 Common - putative tail length tape measure protein ECs1983 45 COG5281 COG5281, Phage-related minor tail protein Function unknown 15831055 Common - putative tail assembly chaperone ECs1801 4 None None None 162139771 Common - hypothetical protein ECs3178 18 COG3013 COG3013, Uncharacterized conserved protein Function unknown 15831334 Common - formate dehydrogenase-N subunit gamma ECs2080 61 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 15831969 Pathogen - EspF-like protein ECs2715 1 None None None 15830434 Common - hypothetical protein ECs1180 1 None None None 15830405 Common - trimethylamine N-oxide reductase cytochrome c-type subunit ECs1151 51 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 15832030 Common - hypothetical protein ECs2776 119 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 15834167 Common thiH thiamine biosynthesis protein ThiH ECs4913 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 15832419 Common - NADH dehydrogenase subunit I ECs3165 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15834144 Common - DNA-binding transcriptional regulator OxyR ECs4890 192 COG0583 LysR, Transcriptional regulator Transcription 15833820 Pathogen - hypothetical protein ECs4566 1 None None None 38703892 Pathogen - hypothetical protein ECs0816 4 None None None 15833827 Common - EscJ ECs4573 28 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 38704076 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase ECs3215 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15834522 Common - hypothetical protein ECs5268 2 None None None 15831897 Common - putative tail protein ECs2643 14 None None None 15831203 Pathogen - hypothetical protein ECs1949 2 None None None 15833359 Common - hypothetical protein ECs4105 103 COG1485 COG1485, Predicted ATPase General function prediction only 15833221 Common - hypothetical protein ECs3967 40 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 15834239 Common - hypothetical protein ECs4985 22 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 15830919 Common - putative transposase ECs1665 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829576 Common - hypothetical protein ECs0322 5 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15833858 Common - regulatory protein UhpC ECs4604 155 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15831271 Pathogen - hypothetical protein ECs2017 2 None None None 15833546 Pathogen - hypothetical membrane protein ECs4292 1 None None None 15834164 Common rpoB DNA-directed RNA polymerase subunit beta ECs4910 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 15833726 Common - hypothetical protein ECs4472 1 None None None 15832729 Common - hypothetical protein ECs3475 217 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 15833312 Common rrmJ 23S rRNA methyltransferase J ECs4058 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 15829951 Common - hypothetical protein ECs0697 202 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 15832347 Common napH quinol dehydrogenase membrane component ECs3093 58 COG0348 NapH, Polyferredoxin Energy production and conversion 15833514 Common - transcriptional regulator MalT ECs4260 56 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 15830300 Common helD DNA helicase IV ECs1046 228 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15834435 Common - hypothetical protein ECs5181 9 None None None 15830765 Pathogen - hypothetical protein ECs1511 4 None None None 15834527 Common - FimA ECs5273 23 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15831650 Common - hypothetical protein ECs2396 4 None None None 38704043 Common - regulator of length of O-antigen component of lipopolysaccharide chains ECs2828 14 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 38704261 Common - hypothetical protein ECs5593 5 None None None 15831242 Pathogen - hypothetical protein ECs1988 1 None None None 15830573 Pathogen - hypothetical protein ECs1319 1 None None None 15831398 Common - hypothetical protein ECs2144 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15829352 Common ftsA cell division protein FtsA ECs0098 181 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15832365 Common - hypothetical protein ECs3111 54 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 15829419 Common - serine endoprotease ECs0165 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15829704 Common phoR phosphate regulon sensor protein ECs0450 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 15832083 Common - UDP-glucose 6-dehydrogenase ECs2829 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 15831824 Common ruvB Holliday junction DNA helicase B ECs2570 233 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 15830260 Common - condesin subunit E ECs1006 20 COG3095 MukE, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 15831809 Common - protease 2 ECs2555 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 15833014 Common - putative permease ECs3760 130 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 15831956 Common - putative outer membrane protein ECs2702 19 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15832412 Common - hypothetical protein ECs3158 10 None None None 38704047 Common - putative chaperone ECs2878 231 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15832216 Common - hypothetical protein ECs2962 4 None None None 15832723 Common rplS 50S ribosomal protein L19 ECs3469 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 15832448 Common - lysine-, arginine-, ornithine-binding periplasmic protein ECs3194 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15833228 Common - glucuronate isomerase ECs3974 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 15833990 Common cyaA adenylate cyclase ECs4736 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 15833748 Common tdh L-threonine 3-dehydrogenase ECs4494 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15830393 Common - hypothetical protein ECs1139 125 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 15831379 Common - autoinducer-2 (AI-2) modifying protein LsrG ECs2125 25 COG1359 COG1359, Uncharacterized conserved protein Function unknown 15830347 Common - putative lipoprotein Rz1 protein precursor ECs1092 1 None None None 15830761 Common - hypothetical protein ECs1507 9 COG4197 COG4197, Uncharacterized protein conserved in bacteria, prophage-related Function unknown 15830482 Common - putative tail fiber protein ECs1228 37 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15830184 Common - predicted inner membrane protein ECs0930 7 None None None 15833281 Common - hypothetical protein ECs4027 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 15830599 Common - hypothetical protein ECs1345 22 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 15834448 Common - hypothetical protein ECs5194 18 COG3054 COG3054, Predicted transcriptional regulator General function prediction only 15834075 Common - formate dehydrogenase accessory protein ECs4821 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 15830340 Common - hypothetical protein ECs1086 3 None None None 15831577 Common - glucuronide transporter ECs2323 79 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15830293 Common - putative ATP-dependent protease ECs1039 115 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 15833654 Common - putative regulator ECs4400 153 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15830725 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase ECs1471 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15831137 Common - DNA-binding transcriptional activator ECs1883 28 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 15832602 Common - hydrogenase 4 subunit F ECs3348 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 15829524 Common proA gamma-glutamyl phosphate reductase ECs0270 192 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 15830140 Common - predicted mechanosensitive channel ECs0886 140 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15834215 Common - putative transcription regulator ECs4961 4 COG5566 COG5566, Uncharacterized conserved protein Function unknown 15832830 Common - formate hydrogenlyase complex iron-sulfur subunit ECs3576 195 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15829525 Common - putative integrase ECs0271 134 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15832852 Common surE stationary phase survival protein SurE ECs3598 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 38704211 Pathogen - hypothetical protein ECs5564 1 None None None 15829986 Common - hypothetical protein ECs0732 49 COG3272 COG3272, Uncharacterized conserved protein Function unknown 15832143 Common - hypothetical protein ECs2889 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15833219 Common - hypothetical protein ECs3965 24 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 15834149 Common - hypothetical protein ECs4895 15 None None None 15830587 Pathogen - hypothetical protein ECs1333 1 None None None 38704025 Common - hypothetical protein ECs2579 30 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 15832113 Common - putative colanic acid biosynthesis acetyltransferase WcaF ECs2859 142 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15830321 Common - hypothetical protein ECs1067 30 COG3668 ParE, Plasmid stabilization system protein General function prediction only 15832632 Common - hypothetical protein ECs3378 44 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 15834519 Pathogen - hypothetical protein ECs5265 2 None None None 15832679 Common - tRNA-specific adenosine deaminase ECs3425 217 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 15833741 Common - preprotein translocase subunit SecB ECs4487 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 15832470 Common - hypothetical protein ECs3216 3 None None None 15830741 Common - respiratory NADH dehydrogenase ECs1487 213 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 15830079 Common - putative terminase large subunit ECs0825 35 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 15832340 Common - cytochrome c-type biogenesis protein CcmE ECs3086 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 15829625 Pathogen - hypothetical protein ECs0371 1 None None None 15830539 Common - putative 3-oxoacyl-(acyl carrier protein) reductase ECs1285 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15832204 Pathogen - putative minor tail protein ECs2950 3 None None None 38704074 Pathogen - hypothetical protein ECs5487 1 None None None 38704165 Common - putative phosphatase ECs4241 39 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15829996 Common - putative chaperone ECs0742 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15830061 Pathogen - hypothetical protein ECs0807 1 None None None 15834316 Common - predicted outer membrane factor of efflux pump ECs5062 115 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 38704085 Common - putative acetyltransferase ECs3305 89 COG0456 RimI, Acetyltransferases General function prediction only 15834058 Common - putative aldolase ECs4804 25 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 162139801 Common maf Maf-like protein ECs1465 194 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 15831655 Common - hypothetical protein ECs2401 97 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 38704146 Common folP dihydropteroate synthase ECs4056 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 15832847 Common - putative phenylacrylic acid decarboxylase ECs3593 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 15832987 Common - EivG ECs3733 60 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 15829398 Common - putative chaperone protein EcpD ECs0144 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 38704206 Common - hypothetical protein ECs4784 17 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 15830479 Pathogen - hypothetical protein ECs1225 3 None None None 15829673 Common tauA taurine transporter substrate binding subunit ECs0419 99 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 15829671 Common - putative sensor histidine protein kinase ECs0417 147 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 15830875 Pathogen - putative holin protein ECs1621 7 None None None 15833851 Common - hypothetical protein ECs4597 22 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 15833414 Common - DNA-directed RNA polymerase subunit alpha ECs4160 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 15831991 Pathogen - putative transcriptional regulator ECs2737 1 None None None 15829286 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase ECs0032 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 38704054 Pathogen - hypothetical protein ECs5480 1 None None None 15830796 Common - putative large terminase subunit ECs1542 35 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 15831035 Common - hypothetical protein ECs1781 3 None None None 38703844 Pathogen - hypothetical protein ECs5363 1 None None None 15829793 Common - putative amino acid/amine transport protein ECs0539 126 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15831227 Pathogen - hypothetical protein ECs1973 1 None None None 15830624 Common - putative glucosyl-transferase ECs1370 22 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 15831249 Pathogen - hypothetical protein ECs1995 2 None None None 15829678 Common - putative flagellin structural protein ECs0424 69 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15833275 Common - putative chaperone ECs4021 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15829780 Common - heat shock protein 90 ECs0526 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 15833806 Common - EscF ECs4552 6 None None None 15829599 Common - hypothetical protein ECs0345 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 15832842 Common - hypothetical protein ECs3588 19 None None None 15833802 Pathogen - hypothetical protein ECs4548 1 None None None 38703941 Common - hypothetical protein ECs5420 3 None None None 15829529 Common - Cro ECs0275 3 None None None 15829661 Common - 4-hydroxy-2-ketovalerate aldolase ECs0407 193 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15832011 Common - hypothetical protein ECs2757 7 None None None 15834424 Common - L-ascorbate-specific enzyme IIB component of PTS ECs5170 16 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 15832711 Common rluD 23S rRNA pseudouridine synthase D ECs3457 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15832222 Common - putative endolysin ECs2968 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15833580 Common - hypothetical protein ECs4326 30 None None None 15830309 Common - putative integrase ECs1055 36 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 15833028 Common - glycine dehydrogenase ECs3774 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 15832795 Common - glycine betaine transporter membrane protein ECs3541 194 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 15830855 Common - sensor protein PhoQ ECs1601 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15833054 Common - putative transporter ECs3800 18 None None None 15834046 Common glnA glutamine synthetase ECs4792 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 15833498 Common - putative transport ECs4244 16 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15829511 Common - hypothetical protein ECs0256 102 COG1360 MotB, Flagellar motor protein Cell motility and secretion 15829602 Common - hypothetical protein ECs0348 2 None None None 15832901 Common - putative glucarate dehydratase ECs3647 57 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 15833008 Common - putative dehydrogenase ECs3754 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 15832257 Pathogen - hypothetical protein ECs3003 2 None None None 15830017 Common - putative glutamate mutase L ECs0763 22 None None None 15829412 Common - glutamate-1-semialdehyde aminotransferase ECs0158 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 15833338 Common - hypothetical protein ECs4084 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 15832194 Pathogen - hypothetical protein ECs2940 1 None None None 15833665 Common - endo-1,4-D-glucanase ECs4411 33 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 15830424 Common - C4-type zinc finger protein (TraR family) ECs1170 9 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15830437 Pathogen - hypothetical protein ECs1183 1 None None None 15834091 Common cpxA two-component sensor protein ECs4837 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15829650 Common lacY galactoside permease ECs0396 19 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 15830658 Common - hypothetical protein ECs1404 4 None None None 15832531 Common - putative transposase TnA ECs3277 74 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833743 Common - hypothetical protein ECs4489 99 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15834119 Pathogen - hypothetical protein ECs4865 1 None None None 15829968 Common fur ferric uptake regulator ECs0714 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15830542 Common - putative aminomethyltransferase ECs1288 168 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 15832202 Common - putative minor tail protein ECs2948 13 COG4718 COG4718, Phage-related protein Function unknown 38703859 Common lacI lac repressor ECs0398 128 COG1609 PurR, Transcriptional regulators Transcription 38704239 Common - exoribonuclease R ECs5155 204 COG0557 VacB, Exoribonuclease R Transcription 38703913 Common etp phosphotyrosine-protein phosphatase ECs1138 126 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 15831852 Common - chemotaxis protein CheA ECs2598 152 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 15832187 Common - putative transposase ECs2933 31 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832168 Common - putative type-1 fimbrial protein ECs2914 6 None None None 15831641 Common - selenocysteine lyase ECs2387 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15831090 Common - anthranilate synthase component I ECs1836 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15831302 Common - putative aldehyde dehydrogenase ECs2048 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15833091 Common - adenine DNA glycosylase ECs3837 231 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 15833029 Common - glycine cleavage system protein H ECs3775 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 15834507 Common - putative integrase ECs5253 98 None None None 15829308 Common apaH diadenosine tetraphosphatase ECs0054 103 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 15833864 Pathogen - hypothetical protein ECs4610 2 None None None 15830135 Common - hypothetical protein ECs0881 25 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15834069 Common - hypothetical protein ECs4815 4 COG3905 COG3905, Predicted transcriptional regulator Transcription 15834558 Common - hypothetical protein ECs5304 68 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15830243 Common - hypothetical protein ECs0989 69 COG2323 COG2323, Predicted membrane protein Function unknown 15829648 Common - cyanate transport ECs0394 72 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 15832808 Common alaS alanyl-tRNA synthetase ECs3554 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 38704139 Common ebgA cryptic beta-D-galactosidase subunit alpha ECs3958 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 15831771 Common - hypothetical protein ECs2517 147 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 15830351 Pathogen - hypothetical protein ECs1098 1 None None None 15833661 Common - hypothetical protein ECs4407 49 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 15832377 Pathogen - hypothetical protein ECs3123 1 None None None 15829539 Common - hypothetical protein ECs0285 7 COG3680 COG3680, Uncharacterized protein conserved in bacteria Function unknown 38704052 Common - putative ATPase ECs2919 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15832384 Common - putative aldolase ECs3130 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 162139727 Common - lytic murein transglycosylase ECs5350 171 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 162139708 Common - fructose-6-phosphate aldolase ECs0903 112 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15830196 Common - hypothetical protein ECs0942 53 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 15831083 Common - hypothetical protein ECs1829 25 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 38704257 Common - hypothetical protein ECs5284 2 None None None 15829389 Common - aspartate alpha-decarboxylase ECs0135 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 15833810 Common - EspA ECs4556 4 None None None 15832074 Common hisG ATP phosphoribosyltransferase ECs2820 203 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 15832007 Pathogen - hypothetical protein ECs2753 5 None None None 15832283 Common - putative isomerase ECs3029 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 15830415 Pathogen - putative excisionase ECs1161 5 None None None 15834112 Common hslU ATP-dependent protease ATP-binding subunit ECs4858 214 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 15832264 Common - hypothetical protein ECs3010 3 None None None 162139776 Common - dihydropyrimidine dehydrogenase ECs3039 173 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 15831205 Common - hypothetical protein ECs1951 1 None None None 15834201 Pathogen - hypothetical protein ECs4947 1 None None None 15832669 Common - hypothetical protein ECs3415 14 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 15833738 Common - putative tRNA/rRNA methyltransferase YibK ECs4484 162 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 15832544 Common pdxK pyridoxal kinase ECs3290 133 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 15832505 Common - hypothetical protein ECs3251 79 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 38703962 Common - putative muconate cycloisomerase I ECs1904 104 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 15831207 Common - putative methyltransferase ECs1953 123 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15834318 Common - predicted membrane fusion protein of efflux pump ECs5064 152 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15831675 Common pheS phenylalanyl-tRNA synthetase subunit alpha ECs2421 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 15831118 Common - putative multidrug-efflux transport protein ECs1864 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 38703931 Common - multidrug resistance protein MdtH ECs1443 103 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 162139744 Common - heat shock chaperone IbpB ECs4626 67 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 15833789 Common - hypothetical protein ECs4535 46 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833949 Common - transcriptional repressor RbsR ECs4695 129 COG1609 PurR, Transcriptional regulators Transcription 15830206 Common - hypothetical protein ECs0952 97 COG0393 COG0393, Uncharacterized conserved protein Function unknown 15830713 Common flgJ peptidoglycan hydrolase ECs1459 73 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 15832592 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase ECs3338 204 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 15830632 Pathogen - hypothetical protein ECs1378 1 None None None 15831411 Pathogen - hypothetical protein ECs2157 1 None None None 15830967 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ECs1713 192 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 15833758 Common - UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase ECs4504 34 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 15829960 Common - transcriptional repressor of N-acetylglucosamine operon ECs0706 169 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15831968 Pathogen - hypothetical protein ECs2714 2 None None None 15834433 Common rplI 50S ribosomal protein L9 ECs5179 211 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 15831548 Common - putative oxidoreductase major subunit ECs2294 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15833300 Common rpsO 30S ribosomal protein S15 ECs4046 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 15830259 Common - condesin subunit F ECs1005 19 COG3006 MukF, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 15831315 Common - RhsE ECs2061 69 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15830721 Common rpmF 50S ribosomal protein L32 ECs1467 88 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 15834098 Common tpiA triosephosphate isomerase ECs4844 227 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 38704035 Common - flagellar biosynthesis protein FliO ECs2686 7 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 15834207 Pathogen - hypothetical protein ECs4953 1 None None None 15833974 Common wecC UDP-N-acetyl-D-mannosamine dehydrogenase ECs4720 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 15830688 Common - hypothetical protein ECs1434 114 COG2353 COG2353, Uncharacterized conserved protein Function unknown 15830903 Common - putative membrane protein precursor ECs1649 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15831280 Common - methyl-accepting chemotaxis protein III ECs2026 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15832536 Common - putative cytochrome oxidase ECs3282 59 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 15834120 Common - hypothetical protein ECs4866 10 COG3863 COG3863, Uncharacterized distant relative of cell wall-associated hydrolases Function unknown 15834137 Common - putative ARAC-type regulatory protein ECs4883 118 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 15830474 Common - putative terminase large subunit ECs1220 14 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 15833593 Common - putative beta-hydroxydecanoyl-ACP dehydrase ECs4339 21 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 15833308 Common secG preprotein translocase subunit SecG ECs4054 126 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 15832693 Common - RNA polymerase sigma factor RpoE ECs3439 175 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 15830783 Pathogen - hypothetical protein ECs1529 2 None None None 15832420 Common - NADH dehydrogenase subunit H ECs3166 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 15832716 Common pheA bifunctional chorismate mutase/prephenate dehydratase ECs3462 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 15832610 Common - hypothetical protein ECs3356 125 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15832867 Common - hypothetical protein ECs3613 6 None None None 15831541 Pathogen - excisionase ECs2287 5 None None None 15830814 Common - putative secreted effector protein ECs1560 4 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15829392 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase ECs0138 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 15830066 Common - NinG ECs0812 12 None None None 15833766 Common rpmB 50S ribosomal protein L28 ECs4512 159 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 15834221 Common - hypothetical protein ECs4967 11 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 38704011 Common - hypothetical protein ECs2456 72 COG0398 COG0398, Uncharacterized conserved protein Function unknown 15829856 Common - H repeat-associated protein ECs0602 34 COG5433 COG5433, Transposase DNA replication, recombination, and repair 38704094 Common - putative 2-component regulator ECs3353 169 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 15829381 Common - multicopper oxidase ECs0127 123 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 38703990 Common - hypothetical protein ECs5444 33 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15832048 Common - putative transposase ECs2794 33 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831095 Common - 23S rRNA pseudouridylate synthase B ECs1841 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15830459 Pathogen - Shiga toxin 2 subunit A ECs1205 2 None None None 15830705 Common flgB flagellar basal body rod protein FlgB ECs1451 99 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 38704102 Common - hypothetical protein ECs3409 54 COG2259 COG2259, Predicted membrane protein Function unknown 15831183 Common - putative transposase ECs1929 90 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15834068 Pathogen - hypothetical protein ECs4814 2 None None None 15834151 Common btuB vitamin B12/cobalamin outer membrane transporter ECs4897 128 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 15831512 Common - putative antirepressor protein ECs2258 8 None None None 15834188 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein ECs4934 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 15834228 Common - putative major head subunit ECs4974 17 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 15832909 Common - hypothetical protein ECs3655 48 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 15833813 Common - gamma intimin ECs4559 38 None None None 15830656 Common - hypothetical protein ECs1402 16 None None None 15831268 Common acpD azoreductase ECs2014 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 15831469 Common - hypothetical protein ECs2215 3 None None None 15832218 Common - hypothetical protein ECs2964 4 None None None 15832891 Common - hypothetical protein ECs3637 22 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 15832397 Common - bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase ECs3143 245 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 15831265 Common - putative phosphatidate cytidiltransferase ECs2011 215 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only 15829822 Common - glyoxylate carboligase ECs0568 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 38704215 Common gldA glycerol dehydrogenase ECs4874 116 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 15829693 Common - hypothetical protein ECs0439 8 None None None 15831877 Pathogen - hypothetical protein ECs2623 1 None None None 15832810 Common recA recombinase A ECs3556 223 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 15832243 Common - putative regulatory protein ECs2989 6 COG1476 COG1476, Predicted transcriptional regulators Transcription 15832572 Common - detox protein ECs3318 43 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 15833196 Common - hypothetical protein ECs3942 168 COG0344 COG0344, Predicted membrane protein Function unknown 15832184 Common - hypothetical protein ECs2930 26 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 15830501 Common - hypothetical protein ECs1247 4 None None None 15833986 Common - putative protoheme IX biogenesis protein ECs4732 46 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 15833686 Common - putative resistance protein ECs4432 105 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 15830358 Common - hypothetical protein ECs1104 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831568 Common - DNA-binding response regulator in two-component regulatory system with RstB ECs2314 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15833656 Common - hypothetical protein ECs4402 50 COG1295 Rbn, Predicted membrane protein Function unknown 15834462 Common - inner membrane ABC transporter permease protein YjfF ECs5208 126 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 15832497 Common - sucrose-6 phosphate hydrolase ECs3243 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 15832338 Common - DsbE ECs3084 107 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 15834040 Common - DNA polymerase I ECs4786 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 15832566 Common - ethanolamine ammonia-lyase heavy chain ECs3312 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 15830324 Pathogen - hypothetical protein ECs1070 2 None None None 15832803 Common - S-ribosylhomocysteinase ECs3549 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 15830119 Common - hypothetical protein ECs0865 3 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 15830733 Common - glucose-specific PTS system IIBC components ECs1479 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15829320 Common - L-arabinose isomerase ECs0066 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 15829483 Common - hypothetical protein ECs0229 47 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 15834323 Common - hypothetical protein ECs5069 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15832274 Common - D-lactate dehydrogenase ECs3020 61 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15831939 Common fliN flagellar motor switch protein FliN ECs2685 124 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15833284 Common - DnaA initiator-associating protein DiaA ECs4030 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 15830446 Pathogen - hypothetical protein ECs1192 3 None None None 38704030 Common - hypothetical protein ECs5464 8 None None None 15831997 Common - putative holin protein ECs2743 5 None None None 38704225 Common - hypothetical protein ECs5010 12 None None None 15834263 Pathogen - hypothetical protein ECs5009 1 None None None 15830052 Common - putative membrane pump protein ECs0798 107 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15834159 Common nusG transcription antitermination protein NusG ECs4905 215 COG0250 NusG, Transcription antiterminator Transcription 15829582 Common - hypothetical protein ECs0328 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830047 Common modC molybdate transporter ATP-binding protein ECs0793 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 15832773 Common - hypothetical protein ECs3519 2 None None None 15834071 Common - formate dehydrogenase accessory protein FdhE ECs4817 42 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 15833081 Common - hypothetical protein ECs3826 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 38704022 Common - hypothetical protein ECs2542 82 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 15833165 Common - hypothetical protein ECs3911 15 COG1359 COG1359, Uncharacterized conserved protein Function unknown 15832604 Common - hydrogenase 4 subunit H ECs3350 106 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15830521 Common - hypothetical protein ECs1267 2 None None None 15832322 Common - hypothetical protein ECs3068 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15831702 Common - hypothetical protein ECs2448 35 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 15831355 Common - putative ATP-binding component of a transport system ECs2101 197 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 15832634 Common ndk nucleoside diphosphate kinase ECs3380 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 162139730 Common - phosphoglycerol transferase I ECs5319 46 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15830551 Common - hypothetical protein ECs1297 3 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 15831109 Common - translation initiation factor Sui1 ECs1855 51 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 15833056 Common - putative ABC transporter ATP-binding subunit ECs3802 241 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15834129 Common - fructose-6-phosphate aldolase ECs4875 113 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15832918 Common - FucU ECs3664 31 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 15831603 Common anmK anhydro-N-acetylmuramic acid kinase ECs2349 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 15833390 Common - DNA-binding transcriptional regulator ECs4136 83 COG1309 AcrR, Transcriptional regulator Transcription 15833506 Common - hypothetical protein ECs4252 9 COG1378 COG1378, Predicted transcriptional regulators Transcription 15829611 Common - choline dehydrogenase ECs0357 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 15832640 Common - hypothetical protein ECs3386 79 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 38703856 Common - transcriptional regulator BetI ECs0359 66 COG1309 AcrR, Transcriptional regulator Transcription 15832520 Common - putative transport protein ECs3266 67 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 38703999 Common bioD putative dithiobiotin synthetase ECs2299 141 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 15831236 Common - hypothetical protein ECs1982 3 None None None 162139794 Common - alcohol dehydrogenase ECs2082 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 15831621 Common - DNA-binding transcriptional repressor PurR ECs2367 129 COG1609 PurR, Transcriptional regulators Transcription 15832055 Common - hypothetical protein ECs2801 23 None None None 15829517 Common prfH peptide chain release factor-like protein ECs0263 215 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 15833397 Common - putative transport system permease protein ECs4143 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15833771 Common pyrE orotate phosphoribosyltransferase ECs4517 160 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 15832329 Common - 16S rRNA pseudouridylate synthase A ECs3075 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 38704179 Common - putative lipase ECs4433 10 COG5571 COG5571, Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion Cell motility and secretion 162139806 Common - nucleotide-binding protein ECs0480 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 15830110 Common bioD dithiobiotin synthetase ECs0856 157 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 15832872 Common - sulfite reductase alpha subunit ECs3618 138 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 15831723 Common - DNA topoisomerase III ECs2469 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15833153 Common - predicted outer membrane lipoprotein ECs3899 12 COG4238 COG4238, Murein lipoprotein Cell envelope biogenesis, outer membrane 15829878 Common - enterobactin/ferric enterobactin esterase ECs0624 28 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 15830823 Pathogen - hypothetical protein ECs1569 1 None None None 15832687 Common rnc ribonuclease III ECs3433 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 15834401 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase ECs5147 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 38703969 Pathogen - hypothetical protein ECs5437 1 None None None 15833897 Common - hypothetical protein ECs4643 4 None None None 15833299 Common - polynucleotide phosphorylase/polyadenylase ECs4045 241 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 15829948 Common - glutamate and aspartate transporter subunit ECs0694 155 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15832741 Pathogen - hypothetical protein ECs3487 2 None None None 162139716 Common - mannose-specific PTS system protein IID ECs2529 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 15829376 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase ECs0122 211 COG1049 AcnB, Aconitase B Energy production and conversion 15831920 Common - cytoplasmic alpha-amylase ECs2666 49 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 15832248 Common - putative regulatory protein ECs2993 2 None None None 15834254 Common - sorbose-permease PTS system IIC component ECs5000 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 15830791 Pathogen - hypothetical protein ECs1537 1 None None None 15832455 Common - hypothetical protein ECs3201 172 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15829448 Common - lipoprotein involved with copper homeostasis and adhesion ECs0194 22 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 15833988 Common hemD uroporphyrinogen-III synthase ECs4734 57 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 15830273 Common - alkanesulfonate transporter substrate-binding subunit ECs1019 100 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 15830984 Common - nitrate reductase 1 beta subunit ECs1730 148 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 15833559 Common - periplasmic binding protein of high-affinity leucine-specific transport system ECs4305 145 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 15831906 Common - response regulator ECs2652 213 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15833521 Common - predicted intramembrane serine protease ECs4267 104 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 15829723 Common nusB transcription antitermination protein NusB ECs0469 196 COG0781 NusB, Transcription termination factor Transcription 15830072 Common - holin protein S ECs0818 5 None None None 15830287 Common - ABC transporter ATPase component ECs1033 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15830894 Common - major tail protein V ECs1640 7 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15830628 Pathogen - hypothetical protein ECs1374 1 None None None 38704097 Common sseA 3-mercaptopyruvate sulfurtransferase ECs3387 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15831226 Common - putative phage major head protein/prohead protease ECs1972 23 COG3740 COG3740, Phage head maturation protease General function prediction only 15831502 Common - putative portal protein ECs2248 64 COG4695 COG4695, Phage-related protein Function unknown 15830647 Common - hypothetical protein ECs1393 15 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15834607 Common - phosphoglycerate mutase ECs5353 172 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 15834288 Common - replicative DNA helicase ECs5034 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15834016 Common - DNA recombination protein RmuC ECs4762 147 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 15833674 Common dppF dipeptide transporter ATP-binding subunit ECs4420 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 15834237 Common - putative DNA circulation protein ECs4983 20 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 15829867 Common - putative inner membrane component for iron transport ECs0613 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 15833169 Common - putative permease of ferrichrome ABC transporter ECs3915 188 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15832000 Common - hypothetical protein ECs2746 3 None None None 15829873 Common - hypothetical protein ECs0619 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 15834560 Common - type I restriction-modification enzyme S subunit ECs5306 59 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 15830886 Common - portal protein ECs1632 32 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 38703989 Common - DNA-binding transcriptional repressor MarR ECs2137 101 COG1846 MarR, Transcriptional regulators Transcription 15832753 Pathogen - hypothetical protein ECs3499 1 None None None 38704192 Common - hypothetical protein ECs5540 5 None None None 15829973 Common - phosphoglucomutase ECs0719 207 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 162139754 Common - hypothetical protein ECs4115 13 None None None 15829709 Common - acyl carrier protein phosphodiesterase ECs0455 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 15832476 Common - putative fimbrial-like protein ECs3222 9 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832312 Common - predicted kinase ECs3058 138 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15829905 Common - hypothetical protein ECs0651 106 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15830988 Common purU formyltetrahydrofolate deformylase ECs1734 219 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 15830096 Common - putative host specificity protein ECs0842 17 COG4733 COG4733, Phage-related protein, tail component Function unknown 15833100 Common - hypothetical protein ECs3846 18 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831471 Common - putative integrase ECs2217 29 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15830216 Common - hypothetical protein ECs0962 32 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 15834499 Common - hypothetical protein ECs5245 5 None None None 15831460 Common - hypothetical protein ECs2206 10 COG5529 COG5529, Pyocin large subunit General function prediction only 15831458 Pathogen - hypothetical protein ECs2204 4 None None None 15830924 Common minC septum formation inhibitor ECs1670 81 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 15829923 Common - hypothetical protein ECs0669 47 COG2921 COG2921, Uncharacterized conserved protein Function unknown 15833117 Common - putative transposase ECs3863 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829272 Common nhaR transcriptional activator NhaR ECs0018 106 COG0583 LysR, Transcriptional regulator Transcription 162139768 Common - detox protein ECs3319 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 15829314 Common djlA Dna-J like membrane chaperone protein ECs0060 70 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 15833246 Common - L-serine deaminase ECs3992 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 15829546 Common - hypothetical protein ECs0292 8 None None None 15831408 Pathogen - hypothetical protein ECs2154 2 None None None 15833175 Common - hypothetical protein ECs3921 26 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 15833650 Common - DNA-binding transcriptional dual regulator ECs4396 17 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15831784 Common - hypothetical protein ECs2530 16 COG4811 COG4811, Predicted membrane protein Function unknown 15831803 Common - hypothetical protein ECs2549 11 None None None 15829754 Common - hypothetical protein ECs0500 108 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15830031 Common - hypothetical protein ECs0777 102 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 38704250 Common - hypothetical protein ECs5233 29 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 15832457 Common - hypothetical protein ECs3203 167 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15832319 Common - hypothetical protein ECs3065 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 15833129 Common - hydrogenase 2 accessory protein HypG ECs3875 72 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15832600 Common - hydrogenase 4 subunit D ECs3346 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 15830044 Common - hypothetical protein ECs0790 6 None None None 15831478 Common - hypothetical protein ECs2224 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830947 Common - putative TonB dependent outer membrane receptor ECs1693 102 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 15829317 Common - ATP-dependent helicase HepA ECs0063 132 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 15830003 Common sdhB succinate dehydrogenase iron-sulfur subunit ECs0749 202 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 15832109 Common - predicted glycosyl transferase ECs2855 85 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15833044 Common - putative coenzyme A transferase ECs3790 94 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 15831027 Common - putative prophage maintenance protein ECs1773 2 None None None 15833122 Common - hypothetical protein ECs3868 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15830146 Common ompX outer membrane protein X ECs0892 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15830286 Common - putative oxidoreductase ECs1032 162 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 15831042 Common - hypothetical protein ECs1788 1 None None None 15831323 Common - cryptic nitrate reductase 2 delta subunit ECs2069 39 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 15832766 Common - putative site specific recombinase ECs3512 16 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15829688 Common psiF hypothetical protein ECs0434 22 None None None 15832100 Common - UTP--glucose-1-phosphate uridylyltransferase subunit GalF ECs2846 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15832514 Common - putative sensor protein ECs3260 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 15832924 Common - cysteine sulfinate desulfinase ECs3670 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15829310 Common ksgA dimethyladenosine transferase ECs0056 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 15830676 Common - hypothetical protein ECs1422 5 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15832623 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein ECs3369 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 38704123 Common - putative lipoprotein ECs3738 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15831591 Common - electron transport complex protein RnfB ECs2337 121 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 15830345 Pathogen - putative transcriptional regulator ECs1091 1 None None None 15831100 Common - DNA topoisomerase I ECs1846 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15834554 Common - putative transport protein ECs5300 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15831651 Common - putative transport system permease protein ECs2397 37 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15833318 Common rpmA 50S ribosomal protein L27 ECs4064 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 15831298 Common - putative transport protein ECs2044 114 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15829290 Common carB carbamoyl phosphate synthase large subunit ECs0036 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15830992 Common - UTP--glucose-1-phosphate uridylyltransferase subunit GalU ECs1738 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15833643 Common hdeB acid-resistance protein ECs4389 5 None None None 15833539 Common - gluconate transporter, low affinity GNT 1 system ECs4285 78 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 15830849 Common - hypothetical protein ECs1595 25 COG1403 McrA, Restriction endonuclease Defense mechanisms 15831572 Common - fumarase A ECs2318 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15834053 Common - putative permease ECs4799 78 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15833959 Common - dihydroxy-acid dehydratase ECs4705 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15833815 Pathogen - Tir ECs4561 1 None None None 38704034 Common - hypothetical protein ECs2667 7 None None None 15833981 Common - putative enterobacterial common antigen polymerase ECs4727 13 None None None 15834380 Common - hypothetical protein ECs5126 5 None None None 15831846 Common - chemotaxis regulator transmitting signal to flagellar motor component ECs2592 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15832820 Common - anaerobic nitric oxide reductase flavorubredoxin ECs3566 125 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15830177 Common - hypothetical protein ECs0923 2 None None None 15833703 Common xylF D-xylose transporter subunit XylF ECs4449 105 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 15829296 Common - crotonobetainyl-CoA dehydrogenase ECs0042 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 15834441 Common - cell morphogenesis/cell wall metabolism regulator ECs5187 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 15831647 Common - hypothetical protein ECs2393 84 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 15831086 Common trpA tryptophan synthase subunit alpha ECs1832 213 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 15829467 Common - hypothetical protein ECs0213 3 None None None 15832484 Common - putative transport ECs3230 40 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 15832582 Common - hypothetical protein ECs3328 16 None None None 15831019 Common - transcriptional repressor DicA ECs1765 8 COG1396 HipB, Predicted transcriptional regulators Transcription 15830758 Common - hypothetical protein ECs1504 2 None None None 15832860 Common - sulfate adenylyltransferase subunit 2 ECs3606 139 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15834574 Common - hypothetical protein ECs5320 14 None None None 15829715 Common - hypothetical protein ECs0461 28 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 15831536 Pathogen - hypothetical protein ECs2282 1 None None None 15833712 Common - putative permease ECs4458 80 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15829812 Common - putative ABC transporter ATP-binding protein YbbA ECs0557 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 15830727 Common - 3-oxoacyl-(acyl carrier protein) synthase II ECs1473 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15830555 Common - transposase ECs1301 17 COG1662 InsB, Transposase and inactivated derivatives, IS1 family DNA replication, recombination, and repair 15831060 Common - putative host specificity protein ECs1806 17 COG4733 COG4733, Phage-related protein, tail component Function unknown 15832271 Common - putative transport system permease protein ECs3017 98 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 15832594 Common dapA dihydrodipicolinate synthase ECs3340 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15834387 Common - fumarate reductase subunit C ECs5133 23 COG3029 FrdC, Fumarate reductase subunit C Energy production and conversion 15834613 Common - DNA-binding response regulator in two-component regulatory system with ArcB or CpxA ECs5359 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15833904 Common - hypothetical protein ECs4650 114 COG0431 COG0431, Predicted flavoprotein General function prediction only 15829643 Common codB cytosine permease ECs0389 69 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 15833109 Common - putative enterotoxin ECs3855 5 None None None 15830290 Common - hypothetical protein ECs1036 26 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 15833615 Common - hypothetical protein ECs4361 2 None None None 15832363 Common - hypothetical protein ECs3109 7 COG5445 COG5445, Predicted secreted protein Function unknown 162139722 Common - DNA-binding transcriptional regulator FrlR ECs4225 128 COG2188 PhnF, Transcriptional regulators Transcription 15832081 Common - bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein ECs2827 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 15833475 Common - predicted fructoselysine transporter ECs4221 188 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15830488 Pathogen - putative outer membrane protein ECs1234 1 None None None 15830778 Common - putative antitermination protein ECs1524 6 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 15834181 Common - transcriptional regulatory protein ZraR ECs4927 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15830949 Pathogen - hypothetical protein ECs1695 1 None None None 15833581 Common - putative acyltransferase ECs4327 70 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 38704018 Common - putative transcriptional regulator LYSR-type ECs2508 174 COG0583 LysR, Transcriptional regulator Transcription 15830180 Common - putative DEOR-type transcriptional regulator ECs0926 30 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 15831243 Common - putative copper/zinc-superoxide dismutase ECs1989 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 15829575 Common - hypothetical protein ECs0321 10 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 15830367 Pathogen - putative minor tail protein ECs1113 2 None None None 15834246 Common - putative DNA-invertase ECs4992 130 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 15829954 Common ubiF 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase ECs0700 130 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 15830673 Common - curlin minor subunit ECs1419 17 None None None 38703924 Common - hypothetical protein ECs5412 1 None None None 38704158 Common - hypothetical protein ECs5530 17 COG3036 COG3036, Uncharacterized protein conserved in bacteria Function unknown 15830685 Common - hypothetical protein ECs1431 67 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15829859 Common - Rhs core protein with extension ECs0605 58 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15833561 Common - hypothetical protein ECs4307 47 COG0456 RimI, Acetyltransferases General function prediction only 15830602 Common - hypothetical protein ECs1348 16 None None None 15830400 Common - cold shock gene ECs1146 2 None None None 15832732 Common - recombination and repair protein ECs3478 201 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 15831937 Common fliL flagellar basal body-associated protein FliL ECs2683 35 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 15829475 Common - hypothetical protein ECs0221 10 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 15832858 Common - adenylylsulfate kinase ECs3604 145 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 15831734 Common - hypothetical protein ECs2480 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 15833928 Common - F0F1 ATP synthase subunit beta ECs4674 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 15832050 Common - hypothetical protein ECs2796 5 None None None 15833964 Pathogen - hypothetical protein ECs4710 4 COG3692 COG3692, Uncharacterized protein conserved in bacteria Function unknown 15833435 Common rpsS 30S ribosomal protein S19 ECs4181 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 15831239 Common - putative minor tail protein ECs1985 14 COG4672 gp18, Phage-related protein Function unknown 15833677 Common - dipeptide transporter permease DppB ECs4423 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15830498 Common - hypothetical protein ECs1244 26 COG3111 COG3111, Uncharacterized conserved protein Function unknown 15831094 Common - hypothetical protein ECs1840 10 None None None 15832964 Common - hypothetical protein ECs3710 1 None None None 15833437 Common rplW 50S ribosomal protein L23 ECs4183 138 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 15832059 Common - putative structural protein ECs2805 10 None None None 162139786 Common - hypothetical protein ECs2495 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15830579 Common ureE urease accessory protein UreE ECs1325 60 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 15831001 Common - OppF ECs1747 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 15829593 Common - hypothetical protein ECs0340 24 COG3059 COG3059, Predicted membrane protein Function unknown 38703877 Common - putative fimbrial-like protein ECs0592 19 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 38704255 Common - hypothetical protein ECs5270 10 None None None 15832781 Common - hypothetical protein ECs3527 36 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 15831443 Common - hypothetical protein ECs2189 3 None None None 162139741 Common - F0F1 ATP synthase subunit I ECs4681 13 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 15832278 Common - acetoin dehydrogenase ECs3024 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 38703862 Common - delta-aminolevulinic acid dehydratase ECs0423 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 15830407 Common torD chaperone protein TorD ECs1153 16 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 15830865 Common - putative replication protein ECs1611 8 None None None 38703890 Common - hypothetical protein ECs0806 2 None None None 15833214 Common - putative oxidoreductase ECs3960 45 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15830665 Common - putative hydrolase ECs1411 43 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 15832232 Common - hypothetical protein ECs2978 4 None None None 15830872 Common - hypothetical protein ECs1618 7 None None None 15833611 Common - HicA-like protein ECs4357 21 None None None 15830840 Pathogen - hypothetical protein ECs1586 2 None None None 15833998 Common - hypothetical protein ECs4744 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 15832919 Common - DNA-binding transcriptional activator ECs3665 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 15831497 Common - putative major tail subunit ECs2243 6 None None None 15830469 Common - putative endopeptidase ECs1215 9 None None None 15833321 Common - DNA-binding transcriptional activator of maltose metabolism ECs4067 22 COG3423 Nlp, Predicted transcriptional regulator Transcription 15833621 Common - UspA ECs4367 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15829445 Common - Rho-binding antiterminator ECs0191 13 COG4568 Rof, Transcriptional antiterminator Transcription 15832683 Common acpS 4'-phosphopantetheinyl transferase ECs3429 139 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 15833939 Common - DNA-binding transcriptional regulator AsnC ECs4685 154 COG1522 Lrp, Transcriptional regulators Transcription 15833173 Common - esterase YqiA ECs3919 47 COG3150 COG3150, Predicted esterase General function prediction only 15830643 Pathogen - hypothetical protein ECs1389 2 None None None 15829783 Common - acetyl esterase ECs0529 109 COG0657 Aes, Esterase/lipase Lipid metabolism 15834305 Common - acetyl-CoA synthetase ECs5051 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15834406 Common - hypothetical protein ECs5152 9 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 15829365 Common - hypothetical protein ECs0111 225 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 38703869 Common - putative LRP-like transcriptional regulator ECs0501 152 COG1522 Lrp, Transcriptional regulators Transcription 38704204 Common - hypothetical protein ECs4750 48 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 162139808 Common - hypothetical protein ECs0436 96 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 38703953 Pathogen - hypothetical protein ECs5428 1 None None None 15829439 Common rnhB ribonuclease HII ECs0185 239 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 15830230 Common lolA outer-membrane lipoprotein carrier protein ECs0976 70 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 15830523 Common - hypothetical protein ECs1269 71 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15830957 Common - dihydroxyacetone kinase subunit M ECs1703 137 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 15833932 Common - F0F1 ATP synthase subunit B ECs4678 127 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 15832660 Common - 3-phenylpropionate dioxygenase ferredoxin subunit ECs3406 87 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 15834450 Common - putative transport protein ECs5196 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15830222 Common clpA ATP-dependent Clp protease ATP-binding subunit ECs0968 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15833075 Common - DNA-specific endonuclease I ECs3821 33 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 15832651 Common - DNA-binding transcriptional repressor ECs3397 162 COG1959 COG1959, Predicted transcriptional regulator Transcription 15829727 Common - putative NAD(P)H-dependent xylose reductase ECs0473 206 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 15834363 Common - hypothetical protein ECs5109 22 COG2388 COG2388, Predicted acetyltransferase General function prediction only 15829903 Common - nucleoside diphosphate kinase regulator ECs0649 75 COG0782 GreA, Transcription elongation factor Transcription 15832714 Common - translation inhibitor protein RaiA ECs3460 91 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 15830024 Common - hypothetical protein ECs0770 15 COG3790 COG3790, Predicted membrane protein Function unknown 15831685 Common - hypothetical protein ECs2431 71 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 15834569 Common - methyl-accepting chemotaxis protein I ECs5315 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15833329 Common - putative calcium/sodium:proton antiporter ECs4075 117 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 15829779 Common recR recombination protein RecR ECs0525 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15831617 Common - hypothetical protein ECs2363 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 15831872 Pathogen - hypothetical protein ECs2618 2 None None None 15831422 Pathogen - minor tail protein ECs2168 3 None None None 15831254 Common - putative oxidoreductase ECs2000 117 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15833428 Common rplX 50S ribosomal protein L24 ECs4174 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 15832840 Common - HypE ECs3586 139 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15831523 Common - hypothetical protein ECs2269 6 None None None 15830297 Common - hypothetical protein ECs1043 19 COG3070 TfoX, Regulator of competence-specific genes Transcription 15830537 Common - hemolysin activator-related protein ECs1283 48 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 15833126 Common - putative low-affinity phosphate transport protein ECs3872 106 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 15830739 Common - beta-hexosaminidase ECs1485 175 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 15833837 Common - type III secretion system protein ECs4583 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 15830429 Common - recombination protein Bet ECs1175 11 None None None 15830951 Common - putative ferric enterobactin transport ATP-binding protein ECs1697 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 38703888 Common - UDP-galactose-4-epimerase ECs0787 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 15831585 Common - adenosine deaminase ECs2331 109 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 15834319 Common - hypothetical protein ECs5065 4 None None None 15832297 Common - DNA-binding transcriptional repressor ECs3043 128 COG1609 PurR, Transcriptional regulators Transcription 15829552 Common - putative head size determination protein ECs0298 4 None None None 15830484 Pathogen - hypothetical protein ECs1230 1 None None None 15833394 Common - hypothetical protein ECs4140 7 None None None 15833430 Common rpsQ 30S ribosomal protein S17 ECs4176 237 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 15834300 Common - hypothetical protein ECs5046 134 COG2252 COG2252, Permeases General function prediction only 15829261 Common - putative inner membrane transport protein ECs0007 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 162139735 Common - soluble pyridine nucleotide transhydrogenase ECs4891 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15829999 Common gltA type II citrate synthase ECs0745 194 COG0372 GltA, Citrate synthase Energy production and conversion 38703887 Common - hypothetical protein ECs5391 15 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 15833333 Common - hypothetical protein ECs4079 69 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 15833370 Common - putative DNA-binding transcriptional regulator ECs4116 180 COG0583 LysR, Transcriptional regulator Transcription 15829406 Common - ATP-dependent RNA helicase HrpB ECs0152 133 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 15829400 Common - 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase ECs0146 197 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 15829916 Common cspE cold shock protein E ECs0662 180 COG1278 CspC, Cold shock proteins Transcription 15833277 Common - truncated putative fimbrial protein ECs4023 2 None None None 15829988 Common - putative transport protein ECs0734 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 15829268 Common dnaK molecular chaperone DnaK ECs0014 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15832677 Common - phosphoribosylformylglycinamidine synthase ECs3423 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 15834371 Common dipZ thiol:disulfide interchange protein precursor ECs5117 111 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 15830227 Common - thioredoxin reductase ECs0973 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15833637 Common - coproporphyrinogen III oxidase ECs4383 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15831396 Pathogen - hypothetical protein ECs2142 1 None None None 15832145 Common - hypothetical protein ECs2891 3 None None None 15829409 Common - iron-hydroxamate transporter ATP-binding subunit ECs0155 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 15829623 Common - putative oxidoreductase subunit ECs0369 179 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 15834213 Pathogen - hypothetical protein ECs4959 1 None None None 15832039 Common - hypothetical protein ECs2785 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 38704202 Common - hypothetical protein ECs5549 2 None None None 15834459 Common - putative LACI-type transcriptional regulator ECs5205 105 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15833501 Common ompR osmolarity response regulator ECs4247 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15831107 Common - hypothetical protein ECs1853 73 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 15833708 Common malS periplasmic alpha-amylase precursor ECs4454 155 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 15831021 Common - hypothetical protein ECs1767 2 None None None 15831667 Common - hypothetical protein ECs2413 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 15833411 Common zntR zinc-responsive transcriptional regulator ECs4157 155 COG0789 SoxR, Predicted transcriptional regulators Transcription 15833385 Common prmA ribosomal protein L11 methyltransferase ECs4131 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 15830752 Common - NAD-dependent deacetylase ECs1498 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 15831011 Common - integrase ECs1757 19 COG0582 XerC, Integrase DNA replication, recombination, and repair 15829710 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase ECs0456 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 15830589 Pathogen - hypothetical protein ECs1335 1 None None None 15834230 Common - hypothetical protein ECs4976 22 COG4387 COG4387, Mu-like prophage protein gp36 Function unknown 15832894 Common - CTP synthetase ECs3640 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 15830730 Common tdk thymidylate kinase ECs1476 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 15830255 Common - 3-deoxy-manno-octulosonate cytidylyltransferase ECs1001 139 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 15829527 Common - hypothetical protein ECs0273 5 None None None 15834022 Common - TatABCE protein translocation system subunit ECs4768 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 15831145 Common - putative transport system permease protein ECs1891 165 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 15830882 Common - hypothetical protein ECs1628 1 None None None 15829902 Pathogen - hypothetical protein ECs0648 2 None None None 15833145 Pathogen - hypothetical protein ECs3891 4 None None None 15833298 Common - lipoprotein NlpI ECs4044 66 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 15833732 Common - hypothetical protein ECs4478 13 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15832114 Common - predicted glycosyl transferase ECs2860 59 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15833235 Common - hypothetical protein ECs3981 10 COG5393 COG5393, Predicted membrane protein Function unknown 15832626 Common - hypothetical protein ECs3372 10 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 15829931 Common nadD nicotinic acid mononucleotide adenyltransferase ECs0677 166 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 15830798 Common - putative portal protein ECs1544 63 COG4695 COG4695, Phage-related protein Function unknown 15834314 Common - hypothetical protein ECs5060 60 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15830291 Common - ribosome modulation factor ECs1037 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 15830236 Common - hypothetical protein ECs0982 77 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 15834398 Common - putative ATPase ECs5144 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 15830077 Pathogen - hypothetical protein ECs0823 1 None None None 15834017 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase ECs4763 222 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15832845 Common - hypothetical protein ECs3591 10 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 15831195 Common - putative transcriptional regulator ECs1941 3 None None None 15834489 Common valS valyl-tRNA synthetase ECs5235 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15832690 Common - SoxR reducing system protein RseC ECs3436 25 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 15830085 Pathogen - hypothetical protein ECs0831 2 None None None 15831037 Common - hypothetical protein ECs1783 2 None None None 15832739 Pathogen - chaperone-like protein ECs3485 2 None None None 15834535 Common - mannonate dehydratase ECs5281 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 15831415 Common - putative host specificity protein ECs2161 18 COG4733 COG4733, Phage-related protein, tail component Function unknown 15831932 Common fliG flagellar motor switch protein G ECs2678 123 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 38704148 Common - hypothetical protein ECs4070 12 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 15833893 Common rnpA ribonuclease P ECs4639 72 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 15833409 Common trkA potassium transporter peripheral membrane component ECs4155 152 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15833456 Common - glutathione-regulated potassium-efflux system ancillary protein KefG ECs4202 63 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15833800 Common - hypothetical protein ECs4546 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832224 Pathogen - hypothetical protein ECs2970 2 None None None 15829428 Common frr ribosome recycling factor ECs0174 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 38704069 Common - hypothetical protein ECs3146 6 None None None 15830010 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase ECs0756 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 15833946 Common rbsC ribose ABC transporter permease protein ECs4692 140 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 15831882 Pathogen - hypothetical protein ECs2628 1 COG1846 MarR, Transcriptional regulators Transcription 15832227 Pathogen - Shiga toxin I subunit B precursor ECs2973 2 None None None 38703903 Common - hypothetical protein ECs0988 44 COG1944 COG1944, Uncharacterized conserved protein Function unknown 162139766 Common engA GTP-binding protein EngA ECs3373 229 COG1160 COG1160, Predicted GTPases General function prediction only 15829631 Common - putative ABC transport system permease ECs0377 109 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 15831822 Common znuC high-affinity zinc transporter ATPase ECs2568 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 15833804 Pathogen - EspF ECs4550 1 None None None 15833407 Common fmt methionyl-tRNA formyltransferase ECs4153 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 15829560 Common - putative oxidoreductase ECs0306 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 15833026 Common - hypothetical protein ECs3772 16 COG3097 COG3097, Uncharacterized protein conserved in bacteria Function unknown 15832529 Common - hypothetical protein ECs3275 6 None None None 15830095 Common - putative tail assembly protein ECs0841 13 COG4723 COG4723, Phage-related protein, tail component Function unknown 15829288 Common - dihydrodipicolinate reductase ECs0034 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 15834106 Common - glycerol facilitator protein ECs4852 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 15834422 Common - putative L-ascorbate 6-phosphate lactonase ECs5168 26 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 15831964 Common - putative sulfite oxidase subunit YedZ ECs2710 78 COG2717 COG2717, Predicted membrane protein Function unknown 15830062 Pathogen - hypothetical protein ECs0808 2 None None None 15831373 Common - putative SORC-type transcriptional regulator ECs2119 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 15833829 Common - EscC ECs4575 135 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 15834520 Pathogen - hypothetical protein ECs5266 5 None None None 15832094 Common - putative glycosyl transferase ECs2840 22 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 38703943 Common - putative prohead protease ECs1591 30 COG3740 COG3740, Phage head maturation protease General function prediction only 15831332 Common - nitrate-inducible formate dehydrogenase-N alpha subunit ECs2078 185 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15830189 Common potG putrescine transporter ATP-binding subunit ECs0935 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15829472 Common - IcmF-like protein ECs0218 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 15833724 Common - rhsA core protein with extension ECs4470 66 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15834025 Common - 3-octaprenyl-4-hydroxybenzoate decarboxylase ECs4771 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 15833856 Common - cryptic adenine deaminase ECs4602 70 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 15833532 Common - aspartate-semialdehyde dehydrogenase ECs4278 195 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15833402 Common - putative ribosome maturation factor ECs4148 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 162139798 Common - potassium/proton antiporter ECs1686 114 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 38704006 Common - short chain acyl-CoA synthetase ECs2408 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15831232 Common - hypothetical protein ECs1978 5 None None None 15833470 Common - nitrite reductase (NAD(P)H) subunit ECs4216 196 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 38703850 Common - hypothetical protein ECs5365 12 None None None 15830339 Common - hypothetical membrane protein ECs1085 32 None None None 38704106 Common - putative transcriptional regulator LYSR-type ECs3443 186 COG0583 LysR, Transcriptional regulator Transcription 15833270 Common - putative tagatose-6-phosphate aldose/ketose isomerase ECs4016 27 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 38704172 Common - putative transporter ECs4358 111 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15830763 Common - hypothetical protein ECs1509 11 COG5529 COG5529, Pyocin large subunit General function prediction only 15833267 Common - N-acetylgalactosamine-specific PTS system enzyme IID component ECs4013 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 15833260 Common - putative hydrolase ECs4006 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 15831067 Common - integrase ECs1813 37 COG0582 XerC, Integrase DNA replication, recombination, and repair 15832403 Common - O-succinylbenzoate synthase ECs3149 68 COG1441 MenC, O-succinylbenzoate synthase Coenzyme metabolism 15834355 Common - alpha-galactosidase ECs5101 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 15831834 Common - hypothetical protein ECs2580 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15830314 Pathogen - hypothetical protein ECs1060 1 None None None 15830575 Common - UreD ECs1321 72 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 15831725 Common - hypothetical protein ECs2471 82 COG0778 NfnB, Nitroreductase Energy production and conversion 15834170 Common thiE thiamine-phosphate pyrophosphorylase ECs4916 203 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 15832771 Common - hypothetical protein ECs3517 2 None None None 15833833 Common - hypothetical protein ECs4579 33 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15830943 Common - putative transposase ECs1689 149 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15831159 Common - murein peptide amidase A ECs1905 18 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 15831385 Common - glutaminase ECs2131 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 15829432 Common - zinc metallopeptidase ECs0178 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15831753 Common - putative ARAC-type regulatory protein ECs2499 69 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15832631 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase ECs3377 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 15830356 Common - hypothetical protein ECs1102 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829391 Common panC pantoate--beta-alanine ligase ECs0137 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 15832806 Common - predicted hydrolase ECs3552 187 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15832245 Pathogen - hypothetical protein ECs2991 1 None None None 15830466 Common - putative holin protein ECs1212 5 None None None 15829819 Common - DNA-binding transcriptional activator of the allD operon ECs0565 172 COG0583 LysR, Transcriptional regulator Transcription 15832652 Common - putative ATP synthase beta subunit ECs3398 157 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 15833874 Common - putative symporter YidK ECs4620 109 COG4146 COG4146, Predicted symporter General function prediction only 15831953 Common - DNA cytosine methylase ECs2699 122 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 38703872 Common - putative metal resistance protein ECs0554 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 15833992 Pathogen - hypothetical protein ECs4737 2 None None None 38704223 Pathogen - hypothetical protein ECs5581 1 None None None 38704060 Common - elongation factor P ECs3063 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15832324 Common - putative transport system permease protein ECs3070 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 15834073 Common - formate dehydrogenase-O iron-sulfur subunit ECs4819 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15831972 Common - putative outer membrane protein precursor ECs2718 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15831342 Common - putative ATP-binding component of a transport system ECs2088 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15833845 Common - hypothetical protein ECs4591 8 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 15834147 Common - putative membrane transport/symporter protein ECs4893 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15832349 Common - putative nitrate reductase 3 ECs3095 185 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15833777 Common gmk guanylate kinase ECs4523 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 15829764 Common - hypothetical protein ECs0510 163 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 15833137 Common - hypothetical protein ECs3883 8 None None None 15832778 Common - gamma-aminobutyrate transporter ECs3524 185 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15833822 Common - EscN ECs4568 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 15832287 Common - hypothetical protein ECs3033 47 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 15830362 Common - putative head-tail preconnector protein ECs1108 140 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 38703899 Common - hypothetical protein ECs0924 122 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15833516 Common - hypothetical protein ECs4262 46 COG3153 COG3153, Predicted acetyltransferase General function prediction only 15832984 Common - ATP synthase SpaL ECs3730 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 15833400 Common - hypothetical protein ECs4146 14 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 15833790 Pathogen - hypothetical protein ECs4536 1 None None None 15831220 Common - putative endopeptidase ECs1966 9 None None None 15832026 Pathogen - hypothetical protein ECs2772 2 None None None 38704045 Common - tyrosine kinase ECs2865 146 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 38704263 Common - putative structural protein ECs5324 53 COG2966 COG2966, Uncharacterized conserved protein Function unknown 15833365 Common - hypothetical protein ECs4111 8 None None None 15833448 Common - hypothetical protein ECs4194 18 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 15829570 Common - putative xanthine dehydrogenase iron-sulfur-binding subunit ECs0316 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 15833681 Common - putative fimbrial protein precursor ECs4427 5 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15829421 Common - putative structural protein ECs0167 17 None None None 15829504 Common - putative amidotransferase ECs0250 71 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 15830767 Common - hypothetical protein ECs1513 7 None None None 15831984 Pathogen - putative major head protein ECs2730 4 None None None 15830781 Common - hypothetical protein ECs1527 3 None None None 38704197 Common - hypothetical protein ECs4633 31 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 15832032 Common - shikimate transporter ECs2778 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15833206 Common - hypothetical protein ECs3952 60 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 15832876 Common - hypothetical protein ECs3622 33 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 15829852 Common - EnvY ECs0598 11 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15830969 Common hemA glutamyl-tRNA reductase ECs1715 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 15829840 Common - UDP-2,3-diacylglucosamine hydrolase ECs0586 78 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 38704001 Pathogen - hypothetical protein ECs5460 1 None None None 15830395 Common - hypothetical protein ECs1141 15 None None None 15830262 Common - hypothetical protein ECs1008 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 15834412 Common - putative alpha helical protein ECs5158 25 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 15830302 Common - hypothetical protein ECs1048 19 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 15834525 Common - tyrosine recombinase/inversion of on/off regulator of fimA ECs5271 210 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15831892 Common - hypothetical protein ECs2638 116 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 15831007 Common - predicted hydrolase ECs1753 131 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 15832474 Common - putative chaperone ECs3220 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15833972 Common - lipopolysaccharide biosynthesis protein WzzE ECs4718 16 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 15832564 Common - hypothetical protein ECs3310 20 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 38704173 Common - Slp ECs4377 30 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 15832390 Common - putative regulator ECs3136 117 COG1414 IclR, Transcriptional regulator Transcription 15832801 Common - multidrug resistance secretion protein ECs3547 151 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 38704013 Common - putative transport system permease protein ECs2461 29 COG4135 COG4135, ABC-type uncharacterized transport system, permease component General function prediction only 15829345 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase ECs0091 213 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15830597 Pathogen - TerW ECs1343 3 COG2378 COG2378, Predicted transcriptional regulator Transcription 15831807 Common - hypothetical protein ECs2553 6 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15834242 Common - hypothetical protein ECs4988 15 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 15831116 Common - putative transcription regulatory protein ECs1862 61 COG1309 AcrR, Transcriptional regulator Transcription 15833744 Common - phosphoglyceromutase ECs4490 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 15830068 Common - putative outer membrane protein ECs0814 23 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 15830409 Common - curved DNA-binding protein CbpA ECs1155 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15832437 Common - putative regulator ECs3183 24 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 15832814 Common - glucitol/sorbitol-specific PTS system component IIA ECs3560 22 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 15834010 Common - predicted hydrolase ECs4756 114 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15832310 Common - putative transport system permease protein ECs3056 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 15829861 Common - Vgr ECs0607 62 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 15833940 Common - asparagine synthetase AsnA ECs4686 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 15830386 Common - hydrogenase-1 operon protein HyaE ECs1132 10 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 15830618 Pathogen - hypothetical protein ECs1364 2 None None None 15829775 Common - hypothetical protein ECs0521 67 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 15832755 Common - putative antitermination protein ECs3501 6 None None None 15834491 Common - leucyl aminopeptidase ECs5237 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 38704092 Common - hydrogenase 4 Fe-S subunit ECs3343 143 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15832427 Common - transcriptional regulator LYSR-type ECs3173 133 COG0583 LysR, Transcriptional regulator Transcription 15832533 Common - hypothetical protein ECs3279 2 None None None 15833143 Common - biopolymer transport protein ExbD ECs3889 138 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 15831123 Common - homolog of Salmonella peptide transport permease protein ECs1869 212 COG4171 SapC, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 15834545 Pathogen - hypothetical protein ECs5291 1 None None None 15829962 Common nagB glucosamine-6-phosphate deaminase ECs0708 81 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 15831555 Common - putative transcriptional regulator LYSR-type ECs2301 191 COG0583 LysR, Transcriptional regulator Transcription 15832538 Common - cell division protein ZipA ECs3284 44 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 38704265 Common - hypothetical protein ECs5595 17 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 38703915 Pathogen - hypothetical protein ECs1218 1 None None None 15830937 Common - hypothetical protein ECs1683 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 15831231 Common - putative head-tail adaptor ECs1977 3 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 15832865 Common - hypothetical protein ECs3611 22 None None None 15831441 Common - hypothetical protein ECs2187 2 None None None 15831358 Common - transcriptional regulator YdeO ECs2104 22 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 15832266 Common - putative excisionase ECs3012 6 None None None 15832743 Pathogen - hypothetical protein ECs3489 1 None None None 15830698 Common - ribosomal-protein-S5-alanine N-acetyltransferase ECs1444 99 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 38704037 Common - hypothetical protein ECs2729 6 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 15831851 Common - purine-binding chemotaxis protein ECs2597 121 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15833913 Pathogen - hypothetical protein ECs4659 1 None None None 38703980 Common - L-asparagine permease ECs2057 174 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15829838 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit ECs0584 191 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 15831638 Common - murein lipoprotein ECs2384 19 COG4238 COG4238, Murein lipoprotein Cell envelope biogenesis, outer membrane 15830700 Common - MviM ECs1446 104 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15833106 Pathogen - hypothetical protein ECs3852 1 None None None 15834153 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase ECs4899 202 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 15830457 Common - antitermination protein Q ECs1203 6 None None None 15834140 Common - acetylornithine deacetylase ECs4886 200 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15831181 Common - ATP-dependent RNA helicase DbpA ECs1927 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15830508 Common - hypothetical protein ECs1254 62 COG0778 NfnB, Nitroreductase Energy production and conversion 15833120 Common - hypothetical protein ECs3866 62 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15829307 Common - CcdB-like protein ECs0053 13 None None None 15834321 Common - putative regulatory protein ECs5067 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15832135 Common - hypothetical protein ECs2881 24 COG4245 TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain General function prediction only 15831899 Common - putative tail sheath protein ECs2645 33 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 15834235 Pathogen - hypothetical protein ECs4981 4 COG4518 COG4518, Mu-like prophage FluMu protein gp41 Function unknown 15831229 Common - hypothetical protein ECs1975 5 None None None 15833112 Pathogen - hypothetical protein ECs3858 3 None None None 15834172 Common - anti-RNA polymerase sigma 70 factor ECs4918 24 COG3160 Rsd, Regulator of sigma D Transcription 15832812 Common - membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan ECs3558 107 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 15833446 Common - 30S ribosomal protein S7 ECs4192 243 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 15832570 Common - EutJ ECs3316 22 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 15833697 Common glyQ glycyl-tRNA synthetase subunit alpha ECs4443 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 15830179 Common - putative DEOR-type transcriptional regulator ECs0925 73 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 15833311 Common hflB ATP-dependent metalloprotease ECs4057 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15834338 Common - PhnG ECs5084 31 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 15833188 Pathogen - hypothetical protein ECs3934 2 None None None 38703918 Common - putative synthetase ECs1257 107 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 15831699 Common - DNA-binding transcriptional activator ECs2445 11 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 15831948 Common - hypothetical protein ECs2694 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15829488 Common - hypothetical protein ECs0234 28 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 15830454 Common - DNA-binding protein ECs1200 28 COG3645 COG3645, Uncharacterized phage-encoded protein Function unknown 15832209 Pathogen - hypothetical protein ECs2955 2 None None None 15832625 Common xseA exodeoxyribonuclease VII large subunit ECs3371 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 38704213 Pathogen - hypothetical protein ECs5565 1 None None None 15833606 Common - putative phosphotransferase system enzyme IIC ECs4352 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 15833208 Common - aerotaxis sensor receptor ECs3954 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 38703929 Common - hypothetical protein ECs1429 7 None None None 15831593 Common rnfD electron transport complex protein RnfD ECs2339 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 15830170 Common bssR biofilm formation regulatory protein BssR ECs0916 6 None None None 15832399 Common arnT 4-amino-4-deoxy-L-arabinose transferase ECs3145 80 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 15834218 Common - hypothetical protein ECs4964 2 None None None 15830651 Common - hypothetical protein ECs1397 10 COG1161 COG1161, Predicted GTPases General function prediction only 15834381 Common - hypothetical protein ECs5127 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 15829983 Common - RhsC ECs0729 67 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 15832370 Common - adhesin ECs3116 65 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15834469 Common - anaerobic ribonucleoside triphosphate reductase ECs5215 100 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 15834379 Common - hypothetical protein ECs5125 16 None None None 38704218 Common thiG thiazole synthase ECs4914 167 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 15829695 Common - hypothetical protein ECs0441 52 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 15831510 Common - endopeptidase ECs2257 9 None None None 15834453 Common - hypothetical protein ECs5199 93 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 15830905 Common - tail fiber assembly protein ECs1651 16 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 15830549 Common - hypothetical protein ECs1295 20 None None None 15830165 Common - putative transport system permease protein ECs0911 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15830232 Common - seryl-tRNA synthetase ECs0978 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15829733 Common - 2-dehydropantoate 2-reductase ECs0479 106 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 15830343 Common - putative transposase ECs1089 30 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832579 Common - malic enzyme ECs3325 216 COG0281 SfcA, Malic enzyme Energy production and conversion 15834413 Common - hypothetical protein ECs5159 10 None None None 15832453 Common - bifunctional folylpolyglutamate synthase/ dihydrofolate synthase ECs3199 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 15833626 Common - glutathione reductase ECs4372 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15832023 Common - hypothetical protein ECs2769 3 None None None 15834114 Common - essential cell division protein ECs4860 30 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 15834086 Common - positive regulator for rhaBAD operon ECs4832 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 15832546 Common cysM cysteine synthase B ECs3292 230 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 15830448 Pathogen - hypothetical protein ECs1194 1 None None None 15833752 Common - ADP-heptose:LPS heptosyltransferase II ECs4498 107 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15830117 Common MoaE molybdopterin synthase large subunit ECs0863 160 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 15831858 Common - trehalose-6-phosphate synthase ECs2604 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 15832103 Common - putative colanic acid biosynthesis glycosyl transferase ECs2849 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15829748 Common - transcriptional regulator HU subunit beta ECs0494 200 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15829410 Common - iron-hydroxamate transporter substrate-binding subunit ECs0156 41 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15833970 Common rho transcription termination factor Rho ECs4716 201 COG1158 Rho, Transcription termination factor Transcription 15830831 Pathogen - Icd-like protein ECs1577 2 None None None 15829336 Common ilvH acetolactate synthase 3 regulatory subunit ECs0082 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 15834475 Common - aspartate carbamoyltransferase regulatory subunit ECs5221 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 15834266 Common - hypothetical protein ECs5012 23 None None None 15833201 Common - O-sialoglycoprotein endopeptidase ECs3947 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 15832701 Common - predicted methyltransferase ECs3447 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15832382 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C ECs3128 179 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 38703960 Common puuD gamma-glutamyl-gamma-aminobutyrate hydrolase ECs1875 122 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 15833841 Pathogen - hypothetical protein ECs4587 1 None None None 15831188 Common - exonuclease VIII ECs1934 14 None None None 15833866 Common - acetolactate synthase catalytic subunit ECs4612 223 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15830723 Common - 3-oxoacyl-(acyl carrier protein) synthase III ECs1469 231 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 15831304 Common - hypothetical protein ECs2050 6 None None None 15829614 Common - choline transport protein BetT ECs0360 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 15834505 Pathogen - hypothetical protein ECs5251 1 None None None 15832196 Common - putative outer membrane protein Lom precursor ECs2942 11 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 15831562 Common pntB pyridine nucleotide transhydrogenase ECs2308 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 15831692 Common katE hydroperoxidase II ECs2438 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 15831800 Common - hypothetical protein ECs2546 10 None None None 15829762 Common - hypothetical protein ECs0508 153 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 15831197 Common - hypothetical protein ECs1943 5 None None None 15834350 Common - predicted metal dependent hydrolase ECs5096 63 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 38704237 Common - ribosome-associated GTPase ECs5140 163 COG1162 COG1162, Predicted GTPases General function prediction only 15833548 Common - hypothetical protein ECs4294 6 None None None 15832903 Common - putative transport protein ECs3649 205 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15829510 Common - FhiA ECs0257 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 15831258 Common - hypothetical protein ECs2004 29 None None None 15830690 Common - hypothetical protein ECs1436 6 None None None 15830711 Common flgH flagellar basal body L-ring protein ECs1457 97 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 15832078 Common hisH imidazole glycerol phosphate synthase subunit HisH ECs2824 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 38704108 Common pssA phosphatidylserine synthase ECs3452 30 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15830413 Common - hypothetical protein ECs1159 7 None None None 15833302 Common rbfA ribosome-binding factor A ECs4048 174 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 15831435 Common - hypothetical protein ECs2181 1 None None None 15833155 Common - repressor protein for FtsI ECs3901 84 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 15833006 Common - putative chlorohydrolase/aminohydrolase ECs3752 129 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15832503 Common - hybrid sensory histidine kinase in two-component regulatory system with EvgA ECs3249 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15833947 Common - D-ribose transporter subunit RbsB ECs4693 133 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 38703864 Common - hypothetical protein ECs0465 8 None None None 15831870 Common - hypothetical protein ECs2616 88 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 15830204 Pathogen - hypothetical protein ECs0950 2 None None None 38704167 Common ugpC glycerol-3-phosphate transporter ATP-binding subunit ECs4296 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 38704137 Common dkgA 2,5-diketo-D-gluconate reductase A ECs3896 186 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 15832511 Common - hypothetical protein ECs3257 3 None None None 15832005 Common - putative crossover junction endodeoxyribonuclease ECs2751 7 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 15830182 Common - hypothetical protein ECs0928 8 None None None 15830194 Common ulaA ascorbate-specific PTS system enzyme IIC ECs0940 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 15831209 Common - hypothetical protein ECs1955 5 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15831962 Common - hypothetical protein ECs2708 64 COG2351 COG2351, Transthyretin-like protein General function prediction only 15834403 Common - putative GTPase HflX ECs5149 232 COG2262 HflX, GTPases General function prediction only 15830540 Common - putative (3R)-hydroxymyristol-(acyl carrier protein) dehydratase ECs1286 166 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 15833217 Common - putative NADPH dehydrogenase ECs3963 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 15833170 Common - putative ABC-type iron-siderophore transport system ATP-binding protein ECs3916 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 15830311 Common - hypothetical protein ECs1057 11 None None None 15829302 Common - putative transport protein ECs0048 163 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 15832659 Common - 3-phenylpropionate dioxygenase subunit beta ECs3405 23 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 15831451 Common - hypothetical protein ECs2197 26 COG3111 COG3111, Uncharacterized conserved protein Function unknown 15832285 Common - putative transport protein ECs3031 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15834096 Common - sulfate transporter subunit ECs4842 91 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 15834432 Common rpsR 30S ribosomal protein S18 ECs5178 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 15829892 Common - putative oxidoreductase ECs0638 57 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 15830439 Common - putative cI repressor protein ECs1185 30 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 15830604 Common - hypothetical protein ECs1350 15 COG0439 AccC, Biotin carboxylase Lipid metabolism 38704112 Common - hypothetical protein ECs3520 12 None None None 15834205 Pathogen - hypothetical protein ECs4951 1 None None None 15831152 Common - outer membrane protein ECs1898 3 None None None 15833519 Common - putative 2-component regulator ECs4265 163 COG4650 RtcR, Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 15834066 Pathogen - hypothetical protein ECs4812 2 None None None 15833878 Common - putative transcriptional regulator ECs4624 125 COG2188 PhnF, Transcriptional regulators Transcription 15830986 Common - nitrate reductase 1 gamma subunit ECs1732 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 15830240 Common - formate acetyltransferase 1 ECs0986 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 38704132 Common - NupG ECs3840 48 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 15830630 Pathogen - hypothetical protein ECs1376 1 None None None 15834443 Common - putative oxidoreductase ECs5190 94 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15833051 Common pgk phosphoglycerate kinase ECs3797 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 38704121 Common - hypothetical protein ECs3681 6 None None None 162139752 Common greB transcription elongation factor GreB ECs4248 201 COG0782 GreA, Transcription elongation factor Transcription 15831214 Pathogen - hypothetical protein ECs1960 1 None None None 15833004 Common - hypothetical protein ECs3750 54 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 15831810 Common - hypothetical protein ECs2556 35 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 15831480 Pathogen - hypothetical protein ECs2226 2 None None None 15832870 Common - hypothetical protein ECs3616 4 None None None 15830289 Common - paraquat-inducible protein B ECs1035 66 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 15830645 Pathogen - BfpM-like protein ECs1391 4 None None None 15831908 Common - DNA-binding transcriptional activator ECs2654 84 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 15829972 Common - replication initiation regulator SeqA ECs0718 23 COG3057 SeqA, Negative regulator of replication initiationR DNA replication, recombination, and repair 15829697 Pathogen - hypothetical protein ECs0443 4 None None None 15831500 Common - putative head-tail adaptor ECs2246 3 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 15829979 Common - potassium-transporting ATPase subunit B ECs0725 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 15834244 Common - putative tail fiber assembly protein ECs4990 8 None None None 15830881 Common - hypothetical protein ECs1627 1 None None None 15832790 Common - glutaredoxin-like protein ECs3536 36 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 15832769 Common - putative ATP-binding component of a transport system ECs3515 103 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15833336 Common - putative sigma(54) modulation protein ECs4082 138 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 15833568 Common - predicted methyltransferase ECs4314 204 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 162139706 Common - regulator protein FrmR ECs0412 70 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 15830592 Common - hypothetical protein ECs1338 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 15833676 Common - dipeptide transporter ECs4422 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15830926 Common - hypothetical protein ECs1672 8 None None None 15831039 Common - antirepressor protein ECs1785 8 None None None 15831985 Pathogen - putative head decoration protein ECs2731 3 None None None 38703992 Common - hypothetical protein ECs5445 11 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15831739 Common - putative oxidoreductase ECs2485 210 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 15829744 Common tig trigger factor ECs0490 217 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 15830271 Common ssuC alkanesulfonate transporter permease subunit ECs1017 190 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 15833663 Common - hypothetical protein ECs4409 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 15830280 Common - hypothetical protein ECs1026 2 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15833541 Common - regulator of gluconate operon ECs4287 127 COG1609 PurR, Transcriptional regulators Transcription 15834063 Common rbn ribonuclease BN ECs4809 117 COG1295 Rbn, Predicted membrane protein Function unknown 15830856 Common - DNA-binding response regulator in two-component regulatory system with PhoQ ECs1602 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15834268 Common xylE D-xylose transporter XylE ECs5014 103 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 15831325 Common - cryptic nitrate reductase 2 alpha subunit ECs2071 104 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 15834191 Common metH B12-dependent methionine synthase ECs4937 180 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 15830238 Common - putative transport ECs0984 72 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 38704241 Common - hypothetical protein ECs5164 8 None None None 15829312 Common - peptidyl-prolyl cis-trans isomerase SurA ECs0058 162 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15834579 Common - putative regulator ECs5325 15 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15832308 Common rihB ribonucleoside hydrolase 2 ECs3054 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 15831863 Common - L-arabinose-binding periplasmic protein ECs2609 38 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15834277 Common ubiA 4-hydroxybenzoate octaprenyltransferase ECs5023 166 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15831016 Pathogen - hypothetical protein ECs1762 2 None None None 15833096 Common - putative transport protein ECs3842 47 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 15831263 Common - hypothetical protein ECs2009 2 None None None 15833335 Common - RNA polymerase factor sigma-54 ECs4081 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 15832301 Common - ferric iron-catecholate outer membrane transporter ECs3047 131 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 15830818 Common - insertion element IS2 transposase InsD ECs1564 91 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 15832797 Common - putative transport protein ECs3543 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15834562 Common - type I restriction-modification enzyme R subunit ECs5308 143 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 15833652 Common - putative cytochrome C peroxidase ECs4398 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 162139810 Common - nucleoprotein/polynucleotide-associated enzyme ECs0409 31 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 15834270 Common malF maltose transporter membrane protein ECs5016 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 15831612 Common - hypothetical protein ECs2357 84 COG1309 AcrR, Transcriptional regulator Transcription 38704115 Common gutQ D-arabinose 5-phosphate isomerase ECs3564 149 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 15829659 Common mhpD 2-keto-4-pentenoate hydratase ECs0405 67 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 15833141 Common - oxidoreductase ECs3887 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15830972 Common - putative transcriptional regulator ECs1718 33 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 15832405 Common - acyl-CoA thioester hydrolase YfbB ECs3151 73 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15829454 Common - DL-methionine transporter permease subunit ECs0200 147 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 15830888 Pathogen - major capsid protein ECs1634 4 None None None 15830874 Common - antitermination protein ECs1620 6 None None None 15832259 Common - hypothetical protein ECs3005 2 None None None 15832839 Common - HypD ECs3585 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15829934 Common leuS leucyl-tRNA synthetase ECs0680 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15832649 Common - scaffold protein ECs3395 154 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 15830812 Common - putative tail assembly protein ECs1558 15 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15830334 Common - prophage maintenance protein ECs1080 6 None None None 15832893 Common eno phosphopyruvate hydratase ECs3639 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 15831467 Pathogen - hypothetical protein ECs2213 1 None None None 15831995 Common - putative endolysin ECs2741 26 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 15833760 Common - glucosyltransferase I ECs4506 159 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 38704020 Common - hypothetical protein ECs5463 8 None None None 15833012 Common - putative oxidoreductase Fe-S subunit ECs3758 156 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15833198 Common - tartrate dehydratase subunit alpha ECs3944 126 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15829914 Common dcuC C4-dicarboxylate transporter DcuC ECs0660 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 15829416 Common - vitamin B12-transporter protein BtuF ECs0162 140 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15834576 Common - primosomal protein I ECs5322 8 COG5529 COG5529, Pyocin large subunit General function prediction only 15830054 Common - putative pectinesterase ECs0800 18 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 15830449 Common - hypothetical protein ECs1195 14 None None None 15830303 Common - hypothetical protein ECs1049 132 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 15832612 Common - DNA replication initiation factor ECs3358 166 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15830245 Common - 3-phosphoshikimate 1-carboxyvinyltransferase ECs0991 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 15830931 Common hlyE hemolysin E ECs1677 2 None None None 15833019 Common - thiol:disulfide interchange protein DsbC ECs3765 66 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15829874 Common - hypothetical protein ECs0620 4 None None None 15829706 Common - proline permease transport protein ECs0452 154 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15831643 Common sufC cysteine desulfurase ATPase component ECs2389 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 15830990 Common - hypothetical protein ECs1736 127 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 15830836 Common - hypothetical protein ECs1582 13 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 15833086 Common - putative alpha helix chain ECs3832 3 None None None 38704041 Common - putative transcriptional regulator LYSR-type ECs2817 159 COG0583 LysR, Transcriptional regulator Transcription 15832014 Pathogen - hypothetical protein ECs2760 1 None None None 15830042 Common - putative molybdenum transport ATP-binding protein ModF ECs0788 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 15834512 Common - hypothetical protein ECs5258 12 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15833934 Common - F0F1 ATP synthase subunit A ECs4680 205 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 15834199 Common - phage transposase ECs4945 15 None None None 15832764 Common - hypothetical protein ECs3510 14 COG4688 COG4688, Uncharacterized protein conserved in bacteria Function unknown 15834370 Common - putative transcriptional regulator ECs5116 33 COG1309 AcrR, Transcriptional regulator Transcription 15831819 Common - lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase ECs2565 85 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 15831601 Common - pyridoxamine 5'-phosphate oxidase ECs2347 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 15833889 Common recF recombination protein F ECs4635 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 15830201 Common artP arginine transporter ATP-binding subunit ECs0947 249 COG4161 ArtP, ABC-type arginine transport system, ATPase component Amino acid transport and metabolism 15831794 Common - carboxy-terminal protease ECs2540 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 15832689 Common - GTP-binding protein LepA ECs3435 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 15833552 Common - glycerol-3-phosphate transporter permease ECs4298 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 15832330 Common - putative ATP-dependent helicase ECs3076 135 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 15831430 Common - putative minor capsid protein precursor ECs2176 178 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15833233 Common - hypothetical protein ECs3979 17 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15829646 Common - carbonic anhydrase ECs0392 153 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 15833058 Common frcK putative fructose transport system kinase ECs3804 65 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 15830707 Common flgD flagellar basal body rod modification protein ECs1453 106 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 15832486 Common - putative DNA injection protein ECs3232 9 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 15834256 Common - sorbose-permease PTS system IIA component ECs5002 34 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 15829544 Common - hypothetical protein ECs0290 9 None None None 15834349 Common - DNA-binding response regulator in two-component regulatory system with BasS ECs5095 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15831466 Pathogen - hypothetical protein ECs2212 1 None None None 15830671 Common - DNA-binding transcriptional activator in two-component regulatory system ECs1417 145 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 15830895 Pathogen - minor tail protein ECs1641 3 None None None 15829328 Common - putative transport protein ECs0074 81 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 15831795 Common - putative solute/DNA competence effector ECs2541 35 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 15830793 Common - hypothetical protein ECs1539 1 None None None 15832156 Common - hypothetical protein ECs2902 62 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 15830040 Common - galactose-1-phosphate uridylyltransferase ECs0786 79 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 15829681 Common - transport protein ECs0427 57 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 15830125 Common - hypothetical protein ECs0871 130 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15829831 Common - hypothetical protein ECs0577 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 162139778 Common - multidrug efflux system subunit MdtA ECs2882 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15832889 Common - hypothetical protein ECs3635 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 15831366 Common - putative fimbrial chaperone protein precursor ECs2112 24 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 15830123 Common - hypothetical protein ECs0869 6 None None None 15830825 Common potA putrescine/spermidine ABC transporter ATPase protein ECs1571 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15830913 Common - hypothetical protein ECs1659 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 38704118 Common - hypothetical protein ECs3638 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 15831913 Common - cystine transporter subunit ECs2659 188 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15830776 Common - hypothetical protein ECs1522 6 None None None 15830804 Common - putative tail assembly chaperone ECs1550 4 None None None 15831787 Common - cold shock-like protein cspC ECs2533 181 COG1278 CspC, Cold shock proteins Transcription 15831922 Common - predicted inner membrane protein ECs2668 46 COG2391 COG2391, Predicted transporter component General function prediction only 162139792 Common - hypothetical protein ECs2291 6 None None None 38704081 Common cysW sulfate/thiosulfate transporter permease subunit ECs3294 224 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 15831361 Common - putative adhesin ECs2107 9 None None None 15831353 Common - putative peptidase ECs2099 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 15829394 Common - putative fimbrial protein ECs0140 4 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 15830051 Common - hypothetical protein ECs0797 56 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 15831543 Common - hypothetical protein ECs2289 11 None None None 15832354 Common - multidrug transporter membrane component/ATP-binding component ECs3100 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 162139718 Common - UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase ECs3141 207 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 38703970 Common - hypothetical protein ECs5438 2 None None None 15833957 Common ilvM acetolactate synthase 2 regulatory subunit ECs4703 22 COG3978 COG3978, Acetolactate synthase (isozyme II), small (regulatory) subunit Function unknown 15833895 Common trmE tRNA modification GTPase TrmE ECs4641 231 COG0486 ThdF, Predicted GTPase General function prediction only 15830137 Common - predicted iron outer membrane transporter ECs0883 111 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 15831288 Common - potassium-tellurite ethidium and proflavin transporter ECs2034 47 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 15831704 Common - succinylglutamate desuccinylase ECs2450 25 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 15833983 Common - putative transport protein YifK ECs4729 124 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 15830166 Common - hypothetical protein ECs0912 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms