Buchnera aphidicola str. APS (Acyrthosiphon pisum), complete genome NC_002528 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 15616645 Common yidC 60 kDa inner-membrane protein BU015 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 15616823 Common guaC guanosine 5'-monophosphate oxidoreductase BU204 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15616735 Common rnfC membrane protein BU115 75 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 15616983 Common nusA transcription elongation factor NusA BU378 216 COG0195 NusA, Transcription elongation factor Transcription 15617064 Common yajR hypothetical protein BU466 204 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15617147 Common murI glutamate racemase BU554 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 15616898 Common gcpE GcpE protein BU287 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 15616846 Common map methionine aminopeptidase BU230 245 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 15617076 Common ppiD peptidyl-prolyl cis-trans isomerase D BU478 75 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15616657 Common yigL hypothetical protein BU028 54 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15616751 Common himA integration host factor alpha-subunit BU131 166 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15616832 Common ftsA cell division protein FtsA BU213 174 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15616730 Common metG methionyl-tRNA synthetase BU109 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616812 Common thrB homoserine kinase BU193 111 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 15617116 Common rplW 50S ribosomal protein L23 BU522 183 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 15616990 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase BU386 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 15617008 Common csrA carbon storage regulator BU404 82 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 15617135 Common deoB phosphopentomutase BU542 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 15617055 Common argA N-acetylglutamate synthase BU456 196 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 15616664 Common rplL 50S ribosomal protein L7/L12 BU035 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 15617142 Common yggS hypothetical protein BU549 196 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 15616777 Common nuoE NADH dehydrogenase subunit E BU157 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 15617089 Common smg Smg protein BU495 39 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 15616863 Common grpE1 heat shock protein GrpE1 BU252 61 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15616682 Common rpsU 30S ribosomal protein S21 BU057 150 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 15616632 Common atpB F0F1 ATP synthase subunit A BU002 203 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 15616998 Common rpsP 30S ribosomal protein S16 BU394 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 15617112 Common rpsC 30S ribosomal protein S3 BU518 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 15617102 Common rplR 50S ribosomal protein L18 BU508 210 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 15616937 Common yjjT hypothetical protein BU328 102 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 15617043 Common leuS leucyl-tRNA synthetase BU444 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616876 Common fabI enoyl-[acyl-carrier-protein] reductase (NADH) BU265 192 COG0623 FabI, Enoyl- acyl-carrier-protein 15616764 Common carB carbamoyl phosphate synthase large subunit BU144 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15616848 Common tsf elongation factor Ts BU232 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 15616668 Common nusG transcription antitermination protein NusG BU039 215 COG0250 NusG, Transcription antiterminator Transcription 28952042 Common priA primosomal protein N' BU120 190 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 15617005 Common rluD ribosomal large subunit pseudouridine synthase D BU401 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15616695 Common fliF flagellar MS-ring protein BU073 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 15616904 Common ybhE 6-phosphogluconolactonase BU293 42 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 15616687 Common bacA bacitracin resistance protein BU062 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 15616791 Common hemK HemK protein BU172 219 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 28952049 Common sohB predicted inner membrane peptidase BU283 183 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15616782 Common nuoJ NADH dehydrogenase I chain J BU162 70 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 15616939 Common mviN virulence factor MviN-like protein BU333 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 15616805 Common smpA small protein A BU186 3 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 15617167 Common rpmE 50S ribosomal protein L31 BU577 180 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15616702 Common fliM flagellar motor switch protein FliM BU080 33 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 15617119 Common rpsJ 30S ribosomal protein S10 BU525 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 15617022 Common cysN sulfate adenylate transferase subunit 1 BU423 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 15616952 Common flgK flagellar hook-associated protein 1 BU346 48 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 15617162 Common mtlD mannitol-1-phosphate 5-dehydrogenase BU571 68 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 15616706 Common fliR flagellar biosynthetic protein FliR BU084 97 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 15616670 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase BU045 147 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 15616923 Common trxB thioredoxin reductase BU314 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15616659 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase BU030 135 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 15616744 Common aroH phospho-2-dehydro-3-heoxyheptonate aldolase BU124 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 15617045 Common ybeN hypothetical protein BU446 168 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 15617182 Common rho transcription termination factor Rho BU596 205 COG1158 Rho, Transcription termination factor Transcription 15617018 Common ygbB hypothetical protein BU419 188 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 15617126 Common yheN hypothetical protein BU532 43 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 15617177 Common pitA low-affinity inorganic phosphate transporter BU587 161 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 15616984 Nonpathogen secG preprotein translocase subunit SecG BU380 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 15616636 Common atpA F0F1 ATP synthase subunit alpha BU006 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 28952048 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase BU261 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 15616761 Common ksgA dimethyladenosine transferase BU141 244 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 28952051 Common flgF flagellar basal body rod protein FlgF BU341 113 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 15617189 Common hscB chaperone protein HscB BU604 38 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 28952058 Common yheL hypothetical protein BU530 19 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 15617096 Common rpsM 30S ribosomal protein S13 BU502 234 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 15616721 Common hisD histidinol-dehydrogenase BU100 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 15616807 Common rnt ribonuclease T BU188 62 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15617158 Common hflC FtsH protease regulator HflC BU567 192 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15617087 Common aroE shikimate 5-dehydrogenase BU493 193 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 15616798 Common nrdA ribonucleotide-diphosphate reductase subunit alpha BU179 206 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15616919 Common rpsA 30S ribosomal protein S1 BU309 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 15616753 Common tgt queuine tRNA-ribosyltransferase BU133 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 15617191 Common fdx ferredoxin 2fe-2s BU606 86 COG0633 Fdx, Ferredoxin Energy production and conversion 15616885 Common yciA hypothetical protein BU274 120 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 15616844 Common htrA serine endoprotease BU228 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15616988 Common greA transcription elongation factor GreA BU384 195 COG0782 GreA, Transcription elongation factor Transcription 15617118 Common rplC 50S ribosomal protein L3 BU524 230 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 15616855 Common proS prolyl-tRNA synthetase BU239 235 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616647 Common groES co-chaperonin GroES BU018 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 15616945 Common flgD basal-body rod modification protein FlgD BU339 93 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 15617082 Common adk adenylate kinase BU484 228 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 15616820 Common secA preprotein translocase subunit SecA BU201 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 15616819 Common mrcB penicillin-binding protein 1b BU200 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 15616680 Common rpoD RNA polymerase sigma factor RpoD BU055 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15616743 Common yb1688 predicted inner membrane protein BU123 73 COG0628 PerM, Predicted permease General function prediction only 15616888 Common trpA tryptophan synthase subunit alpha BU277 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 15616911 Common ybgI hypothetical protein BU301 94 COG0327 COG0327, Uncharacterized conserved protein Function unknown 15617062 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase BU464 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 15617109 Common rpsQ 30S ribosomal protein S17 BU515 232 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 15617130 Common trpS tryptophanyl-tRNA synthetase BU536 228 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15617036 Common lysS lysyl-tRNA synthetase BU437 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15616711 Common pmbA PmbA protein BU089 155 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15616810 Common ychF translation-associated GTPase BU191 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 15616874 Common purB adenylosuccinate lyase BU263 224 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 15616928 Common pykA pyruvate kinase BU319 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 15617031 Common yihA GTPase EngB BU432 177 COG0218 COG0218, Predicted GTPase General function prediction only 15616996 Common pheA chorismate mutase BU392 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 15617114 Common rpsS 30S ribosomal protein S19 BU520 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 15616837 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase BU219 212 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15616930 Common htpX heat shock protein HtpX BU321 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15617057 Common ribH 6,7-dimethyl-8-ribityllumazine synthase BU459 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 15617140 Common gshB glutathione synthetase BU547 121 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 15616770 Common ribF FMN adenylyltransferase BU150 211 COG0196 RibF, FAD synthase Coenzyme metabolism 15616666 Common rplA 50S ribosomal protein L1 BU037 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 15616779 Common nuoG NADH dehydrogenase subunit G BU159 182 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 15616634 Common atpF ATP synthase B chain BU004 107 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 15616869 Common rnc ribonuclease III BU258 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 15617137 Common yhgI hypothetical protein BU544 44 COG0316 IscA, Uncharacterized conserved protein Function unknown 15617012 Common yggJ hypothetical protein BU410 181 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 15617100 Common rpmD 50S ribosomal protein L30 BU506 141 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 15617094 Common rpsD 30S ribosomal protein S4 BU500 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15617160 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase BU569 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 15616700 Nonpathogen yba1 hypothetical protein BU078 1 None None None 15616879 Common lipB lipoate-protein ligase B BU268 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 15617166 Common amiB N-acetylmuramoyl-L-alanine amidase precursor BU576 169 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15616967 Common pyrD dihydroorotate dehydrogenase 2 BU362 161 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 15617024 Common cysG ferrochelatase BU425 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 15617145 Common mutY A/G-specific adenine glycosylase BU552 231 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 15616704 Common fliP type III secretion system protein BU082 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 15617156 Common vacB VacB protein BU565 201 COG0557 VacB, Exoribonuclease R Transcription 15616796 Common yfaE hypothetical protein BU177 27 COG0633 Fdx, Ferredoxin Energy production and conversion 15617180 Common cyaY CyaY protein BU590 36 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 15617080 Common ybaB hypothetical protein BU482 159 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 15617010 Common metK S-adenosylmethionine synthetase BU408 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 15616921 Common serC phosphoserine aminotransferase BU312 98 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 15617038 Common lgt prolipoprotein diacylglyceryl transferase BU439 199 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 15616976 Common yhaR hypothetical protein BU371 155 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15616906 Common ycfU hypothetical protein BU295 87 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15616800 Common yba2 hypothetical protein BU181 20 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 15616685 Common yb3052 kinase BU060 126 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 15616909 Common fldA flavodoxin FldA BU299 70 COG0716 FldA, Flavodoxins Energy production and conversion 15617026 Common cysI sulfite reductase (NADPH) hemoprotein beta-component BU427 141 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 15616640 Common gyrB DNA gyrase subunit B BU010 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15616971 Common valS valyl-tRNA synthetase BU366 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15617003 Common aroD 3-dehydroquinate dehydratase BU399 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 15616830 Common yadR hypothetical protein BU211 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 15616917 Common tpiA triosephosphate isomerase BU307 221 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 15617006 Common yfiO hypothetical 27.8 kDa lipoprotein BU402 106 COG4105 ComL, DNA uptake lipoprotein General function prediction only 15616809 Common pth peptidyl-tRNA hydrolase BU190 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 15616690 Common ptsH phosphocarrier protein HPr BU065 126 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 15616900 Common glyA serine hydroxymethyltransferase BU289 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 15616712 Common yraL hypothetical protein BU091 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 15617078 Common mdlB multidrug resistance-like ATP-binding protein MdlB BU480 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15616850 Common frr ribosome recycling factor BU234 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 15617175 Nonpathogen yba4 hypothetical protein BU585 1 None None None 15616697 Common fliH flagellar assembly protein FliH BU075 14 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 28952046 Common flhA flagellar biosynthesis protein A BU241 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 15616785 Common nuoM NADH dehydrogenase I chain M BU165 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 15616839 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase BU221 208 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15617121 Common fusA elongation factor G BU527 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15617128 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein BU534 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 15616675 Common argG argininosuccinate synthase BU050 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 15616723 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase BU102 217 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 15616954 Common rluC ribosomal large subunit pseudouridine synthase C BU348 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15616994 Common rpsI 30S ribosomal protein S9 BU390 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 15617011 Common endA endonuclease I BU409 33 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 15616638 Common atpD F0F1 ATP synthase subunit beta BU008 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 15616654 Common rpoH RNA polymerase factor sigma-32 BU025 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15616772 Common dnaJ DnaJ protein BU152 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 28952054 Common yhgN putative eubacterial dITP- and XTP- hydrolyzing enzyme BU449 140 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 15616943 Common flgB flagellar basal-body rod protein FlgB BU337 85 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 15616933 Common yeaZ hypothetical protein BU324 46 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 15616661 Common hupA DNA-binding protein hu-alpha BU032 214 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15617132 Common aroB 3-dehydroquinate synthase BU538 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 15616771 Common rpsT 30S ribosomal protein S20 BU151 113 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 15617184 Common rep ATP-dependent DNA helicase Rep BU598 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15616827 Common speD S-adenosylmethionine decarboxylase BU208 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 15617146 Common yggX hypothetical protein BU553 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 15616787 Common folC dihydrofolate synthase BU167 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 15617034 Common ygfZ hypothetical protein BU435 63 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 15616768 Common lspA lipoprotein signal peptidase BU148 179 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15616649 Common efp elongation factor P BU020 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15617061 Common nusB transcription antitermination protein NusB BU463 176 COG0781 NusB, Transcription termination factor Transcription 15616739 Common nth endonuclease III BU119 236 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 15616835 Common ftsW cell division protein FtsW BU217 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15616987 Common ftsJ cell division protein FtsJ BU383 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 15616817 Common dksA DnaK suppressor protein BU198 117 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15616642 Common dnaA chromosomal replication initiator protein DnaA BU012 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15617046 Common yhhP hypothetical protein BU447 42 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 15616891 Common trpD anthranilate phosphoribosyltransferase BU280 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 28952045 Common aceF branched-chain alpha-keto acid dehydrogenase subunit E2 BU206 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 15617072 Common tig trigger factor BU474 144 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 15616956 Common fabG 3-oxoacyl-[acyl-carrier protein] reductase BU351 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15616883 Common hns DNA-binding protein H-ns BU272 22 COG2916 Hns, DNA-binding protein H-NS General function prediction only 15616856 Common flhB flagellar biosynthesis protein FlhB BU240 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 15616758 Common rplY 50S ribosomal protein L25 BU138 71 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 15617129 Common yhfC hypothetical protein BU535 36 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 15617107 Common rplX 50S ribosomal protein L24 BU513 195 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 15616978 Common pnp polynucleotide phosphorylase/polyadenylase BU373 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 15616725 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BU104 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 15616734 Common rnfB ferredoxin II BU114 110 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 15616719 Common yb2331 hypothetical protein BU098 59 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 15616915 Common pfkA 6-phosphofructokinase BU305 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 15616765 Common carA carbamoyl phosphate synthase small subunit BU145 236 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 15616851 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase BU235 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 15617092 Common rplQ 50S ribosomal protein L17 BU498 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 15616968 Common ycbY hypothetical protein BU363 150 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 15616691 Common cysK cysteine synthase A BU066 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 15617016 Common eno enolase BU417 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 15616698 Common fliI flagellum-specific ATP synthase BU076 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 15617186 Common ilvD dihydroxy-acid dehydratase BU600 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15617028 Common mutS DNA mismatch repair protein BU429 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15616795 Common pta phosphate acetyltransferase BU176 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 15616944 Common flgC flagellar basal-body rod protein FlgC BU338 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 15616710 Common ppa inorganic pyrophosphatase BU088 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 15617000 Common trmD tRNA (guanine-N1)-methyltransferase BU396 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 15616801 Common ahpC alkyl hydroperoxide reductase BU182 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15617067 Common cyoD cytochrome O ubiquinol oxidase subunit IV BU469 27 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 15617144 Common yggH hypothetical protein BU551 156 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 15616981 Common rbfA ribosome-binding factor A BU376 147 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 15616877 Common rnb exoribonuclease II BU266 185 COG4776 Rnb, Exoribonuclease II Transcription 161353756 Common rplF 50S ribosomal protein L6 BU509 228 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 15616652 Common yhhF hypothetical protein BU023 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 15617099 Common rplO 50S ribosomal protein L15 BU505 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 15616902 Common bioB biotin synthetase BU291 182 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15617164 Common pgi glucose-6-phosphate isomerase BU573 188 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 15616728 Common gnd 6-phosphogluconate dehydrogenase BU107 163 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 15616948 Common flgG flagellar basal body rod protein FlgG BU342 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15616714 Common talA transaldolase B BU093 125 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15617183 Common trxA thioredoxin BU597 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15616861 Common gmhA phosphoheptose isomerase BU250 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 15616663 Common rpoB DNA-directed RNA polymerase subunit beta BU034 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 15617134 Common deoD purine nucleoside phosphorylase BU541 94 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 15617041 Common ybeY hypothetical protein BU442 194 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 15617032 Common typA GTP-binding protein BipA BU433 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 15617086 Common cspE cold shock protein E BU489 180 COG1278 CspC, Cold shock proteins Transcription 15616709 Common ytfN hypothetical protein BU087 25 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 15617178 Common ynfM hypothetical protein BU588 192 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15616935 Common minD septum site-determining protein MinD BU326 145 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 15617111 Common rplP 50S ribosomal protein L16 BU517 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 15617194 Common ftsL cell division protein BU223m 9 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 15617154 Common rpsR 30S ribosomal protein S18 BU563 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 15617090 Common def polypeptide deformylase BU496 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 15616631 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA BU001 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15616992 Common rpmA 50S ribosomal protein L27 BU388 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 15616941 Nonpathogen flgN flagella synthesis protein FlgN BU335 1 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15616774 Common nuoA NADH dehydrogenase I chain A BU154 161 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 15616865 Common smpB SsrA-binding protein BU254 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 15616985 Common mrsA MrsA protein BU381 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15616868 Common era GTP-binding protein Era BU257 210 COG1159 Era, GTPase General function prediction only 15617053 Common recB exodeoxyribonuclease V 135 kDa polypeptide BU454 186 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 15616732 Common ribE riboflavin synthase subunit alpha BU112 208 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 15616678 Common secB preprotein translocase subunit SecB BU053 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 15616841 Common yabC hypothetical protein BU224 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 15616813 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I BU194 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15617173 Common kdtB lipopolysaccharide core biosynthesis protein kDatB BU583 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 15616829 Common pfs 5'-methylthioadenosine nucleosidase BU210 97 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15616815 Common panC pantoate-beta-alanine ligase BU196 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 15617149 Common yeeX hypothetical protein BU556 22 COG2926 COG2926, Uncharacterized protein conserved in bacteria Function unknown 15616893 Common yciL hypothetical protein BU282 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15616913 Common sucB 2-oxoglutarate dehydrogenase E2 component BU303 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 15617171 Common fpr ferredoxin-NADP reductase BU581 92 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 15616763 Common folA dihydrofolate reductase BU143 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 15616821 Common mutT mutator MutT protein BU202 73 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15616727 Common hisI phosphoribosyl-AMP cyclohydrolase BU106 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 15616672 Common argE acetylornithine deacetylase BU047 157 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15616950 Common flgI flagellar basal body P-ring protein BU344 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 15616749 Common pheS phenylalanyl-tRNA synthetase subunit alpha BU129 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 15617097 Common rpmJ 50S ribosomal protein L36 BU503 129 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 15616633 Common atpE F0F1 ATP synthase subunit C BU003 50 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 15616650 Common dnaC DNA replication protein DnaC BU021 61 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 15616693 Common gltX glutamyl-tRNA synthetase BU070 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15616717 Common dapA dihydrodipicolinate synthase BU096 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15616958 Common tmk thymidylate kinase BU353 218 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 15616676 Common argH argininosuccinate lyase BU051 230 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 15616853 Common yaeT hypothetical protein BU237 152 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 15616746 Common infC translation initiation factor IF-3 BU126 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 15616875 Common mltE membrane-bound lytic murein transglycosylase E BU264 84 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15617058 Common thiL thiamin-monophosphate kinase BU460 194 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 15617152 Common cysQ CysQ protein BU561 130 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 15617014 Common glnS glutaminyl-tRNA synthetase BU415 231 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15617161 Common mutL DNA mismatch repair protein MutL BU570 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 15617074 Common clpX ATP-dependent protease ATP-binding subunit BU476 209 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 15616925 Common aspS aspartyl-tRNA synthetase BU316 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616936 Common minC cell division inhibitor MinC BU327 85 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 15617084 Common cysS cysteinyl-tRNA synthetase BU487 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616833 Common murC UDP-N-acetylmuramate-alanine ligase BU215 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 15617193 Common yfgM hypothetical protein BU608 9 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 28952044 Common prsA ribose-phosphate pyrophosphokinase BU169 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15617105 Common rpsN 30S ribosomal protein S14 BU511 210 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 15617021 Common cysC adenylylsulfate kinase BU422 144 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 15616927 Common znuC high-affinity zinc uptake system ATP-binding protein ZnuC BU318 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 15616793 Common nadE NAD synthetase BU174 132 COG0171 NadE, NAD synthase Coenzyme metabolism 15616683 Common ygjD O-sialoglycoprotein endopeptidase BU058 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 15616803 Common grpE heat shock protein GrpE2 BU184 99 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15616964 Common ompF OmpF-like porin BU359 20 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 15616972 Common pepA aminopeptidase A/I BU367 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 15616963 Nonpathogen ycfM hypothetical protein BU358 1 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 15616790 Common prfA peptide chain release factor 1 BU171 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 28952059 Common dnaB replicative DNA helicase BU546 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15616781 Common nuoI NADH dehydrogenase subunit I BU161 193 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15616806 Common ydhD hypothetical protein BU187 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 15616651 Common dnaT primosomal protein I BU022 8 COG5529 COG5529, Pyocin large subunit General function prediction only 15616938 Common ompA outer membrane protein A precursor BU332 95 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15616922 Common serS seryl-tRNA synthetase BU313 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616905 Common mfd transcription-repair coupling factor BU294 220 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 15616688 Common crr glucose-specific PTS system component BU063 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 15617157 Common purA adenylosuccinate synthetase BU566 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 15616966 Common pncB nicotinate phosphoribosyltransferase BU361 72 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 15617002 Common tldD TldD protein BU398 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15617044 Common holA DNA polymerase III delta subunit BU445 31 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 15616745 Common thrS threonyl-tRNA synthetase BU125 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15617101 Common rpsE 30S ribosomal protein S5 BU507 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 28952052 Common ptsG glucose-specific PTS system IIBC components BU356 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 15616873 Common ycfC hypothetical protein BU262 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 15617023 Common cysD sulfate adenylyltransferase subunit 2 BU424 125 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15616880 Common lipA lipoyl synthase BU269 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 15616707 Common rpmG 50S ribosomal protein L33 BU085 139 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 15617176 Common yhiQ hypothetical protein BU586 54 None None None 15616696 Common fliG flagellar motor switch protein FliG BU074 119 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 15617009 Common gshA glutamate-cysteine ligase BU407 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 15616910 Common phrB deoxyribodipyrimidine photolyase BU300 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 15616887 Common yciC hypothetical protein BU276 15 None None None 15616703 Common fliN flagellar motor switch protein FliN BU081 121 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15617095 Common rpsK 30S ribosomal protein S11 BU501 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 15616637 Common atpG F0F1 ATP synthase subunit gamma BU007 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 15616953 Common rne ribonuclease E BU347 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 28952043 Common glyQ glycyl-tRNA synthetase subunit alpha BU136 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 15617127 Common fkpA FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor BU533 125 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 15616918 Common himD integration host factor beta-subunit BU308 197 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15617181 Common hemC porphobilinogen deaminase BU591 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 15617188 Common iscU scaffold protein BU603 147 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 15616720 Common hisG ATP phosphoribosyltransferase BU099 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 15616769 Common ileS isoleucyl-tRNA synthetase BU149 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616808 Common sodA superoxide dismutase BU189 206 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 15616824 Common aceE pyruvate dehydrogenase subunit E1 BU205 144 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 15616811 Common thrC threonine synthase BU192 200 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 15617015 Common pyrG CTP synthetase BU416 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 15616713 Common fabB 3-oxoacyl-[acyl-carrier-protein] synthase I BU092 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15617088 Common yrdC hypothetical protein BU494 168 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 15616940 Common pyrC dihydroorotase BU334 89 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 15616870 Common lepB signal peptidase I BU259 194 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15616889 Common trpB tryptophan synthase subunit beta BU278 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 15617148 Common sbcB exonuclease I BU555 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 15617054 Common recD exodeoxyribonuclease V 67 kDa polypeptide BU455 120 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 15617063 Common ispA geranyltranstransferase BU465 229 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15616991 Common rplU 50S ribosomal protein L21 BU387 207 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 15616681 Common dnaG DNA primase BU056 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15616656 Common glmU UDP-N-acetylglucosamine pyrophosphorylase BU027 230 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 15617115 Common rplB 50S ribosomal protein L2 BU521 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 15616831 Common ftsZ cell division protein FtsZ BU212 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 15616778 Common nuoF NADH dehydrogenase I chain F BU158 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 15616864 Common yfjF hypothetical protein BU253 62 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 15616635 Common atpH ATP synthase delta chain BU005 131 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 15616669 Common secE preprotein translocase subunit SecE BU040 24 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 15616999 Common rimM 16S rRNA processing protein RimM BU395 109 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 15617159 Common hflK HflK protein BU568 182 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15617136 Common prfC peptide chain release factor 3 BU543 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 15616738 Common ydgQ SoxR-reducing system protein RsxE BU118 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 15617030 Common polA DNA polymerase I BU431 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 15616882 Common ribA GTP cyclohydrolase II BU271 186 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 15616974 Common pyrB aspartate carbamoyltransferase catalytic subunit BU369 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 15616665 Common rplJ 50S ribosomal protein L10 BU036 175 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 15616847 Common rpsB 30S ribosomal protein S2 BU231 220 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 15616895 Common topA DNA topoisomerase I BU284 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15616644 Common rnpA ribonuclease P protein component BU014 48 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 15616679 Common cysE serine acetyltransferase BU054 208 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 15616860 Common dnaQ DNA polymerase III epsilon chain BU248 185 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15616838 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase BU220 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 15616852 Common uppS undecaprenyl pyrophosphate synthetase BU236 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15616701 Common fliK flagellar hook-length control protein BU079 17 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 28952050 Common flgE flagellar hook protein FlgE BU340 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 15616970 Common yceA hypothetical protein BU365 116 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 15616705 Common fliQ flagellar biosynthetic protein FliQ BU083 61 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 15617070 Common cyoA cytochrome O ubiquinol oxidase subunit II BU472 105 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 15616871 Common lepA GTP-binding protein LepA BU260 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 15617025 Common cysH phosphoadenosine phosphosulfate reductase BU426 150 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 15616641 Common dnaN DNA polymerase III beta chain BU011 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 28952057 Common tufB elongation factor Tu BU526 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15617168 Common hslV ATP-dependent protease peptidase subunit BU578 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 15617027 Common cysJ sulfite reductase (NADPH) flavoprotein alpha-component BU428 99 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 15616899 Common hisS histidyl-tRNA synthetase BU288 240 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616892 Common yedA hypothetical protein BU281 12 None None None 15616960 Common ycfH hypothetical protein BU355 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15616901 Common bioD dethiobiotin synthetase BU290 119 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 15617039 Common thyA thymidylate synthase BU440 138 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 15616907 Common ycfV hypothetical ABC transporter ATP-binding protein YcfV BU296 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15616979 Common rpsO 30S ribosomal protein S15 BU374 208 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 15616686 Common cca tRNA CCA-pyrophosphorylase BU061 201 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15617155 Common rpsF 30S ribosomal protein S6 BU564 164 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 15617108 Common rplN 50S ribosomal protein L14 BU514 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 15616762 Common apaH diadenosine tetraphosphatase BU142 87 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 161353757 Common dcd deoxycytidine triphosphate deaminase BU108 125 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 15617081 Common htpG heat shock protein 90 BU483 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 15616859 Common gloB probable hydroxyacylglutathione hydrolase BU246 175 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15616845 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase BU229 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 15616916 Common glpF glycerol uptake facilitator protein BU306 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 15617019 Common ygbP hypothetical protein BU420 192 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 15616783 Common nuoK NADH dehydrogenase I chain K BU163 40 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 15616767 Common lytB LytB protein BU147 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 15617187 Common yfhO hypothetical protein BU602 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 15617165 Common orn oligoribonuclease BU574 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 15616955 Common rpmF 50S ribosomal protein L32 BU349 91 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 15616722 Common hisC histidinol-phosphate aminotransferase BU101 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 15617093 Common rpoA DNA-directed RNA polymerase subunit alpha BU499 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 15616674 Common argB acetylglutamate kinase BU049 166 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 28952041 Common ydgO hypothetical protein BU116 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 15617007 Common alaS alanyl-tRNA synthetase BU403 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15617150 Common pyrE orotate phosphoribosyltransferase BU559 113 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 15617174 Nonpathogen yba3 hypothetical protein BU584 1 None None None 15617079 Common dnaX DNA polymerase III subunits gamma and tau BU481 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15616799 Common gyrA DNA gyrase subunit A BU180 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15616784 Common nuoL NADH dehydrogenase I chain L BU164 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 15617117 Common rplD 50S ribosomal protein L4 BU523 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 15616786 Common nuoN NADH dehydrogenase I chain N BU166 204 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 15616843 Common ilvI acetolactate synthase large subunit BU226 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 28952039 Common trmE tRNA modification GTPase TrmE BU016 223 COG0486 ThdF, Predicted GTPase General function prediction only 15617122 Common rpsG 30S ribosomal protein S7 BU528 238 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 15616858 Common argS arginyl-tRNA synthetase BU242 238 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616932 Common yoaE hypothetical protein BU323 212 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15617069 Common cyoB cytochrome O ubiquinol oxidase subunit I BU471 165 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 15616826 Common lpdA dihydrolipoamide dehydrogenase BU207 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15617190 Common hscA heat shock protein HscA BU605 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15616660 Common purH IMP cyclohydrolase BU031 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 15616639 Common atpC ATP synthase epsilon chain BU009 153 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 15616742 Common ydiC hypothetical protein BU122 26 COG0316 IscA, Uncharacterized conserved protein Function unknown 15616982 Common infB translation initiation factor IF-2 BU377 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 15617077 Common mdl multidrug resistance-like ATP-binding protein Mdl BU479 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28952040 Common glmS D-fructose-6-phosphate amidotransferase BU026 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 15616897 Common yfgB hypothetical protein BU286 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 15616989 Common yrbA hypothetical protein BU385 38 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 15617131 Common rpe ribulose-phosphate 3-epimerase BU537 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 15616754 Common yajC hypothetical protein BU134 164 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 15616890 Common trpC bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase BU279 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 28952047 Common gpt xanthine-guanine phosphoribosyltransferase BU251 68 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15617138 Common ssb single-strand binding protein BU545 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15617037 Common lysA diaminopimelate decarboxylase BU438 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 15616977 Common deaD ATP-dependent RNA helicase DeaD BU372 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15616997 Common ffh signal recognition particle protein BU393 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 15616931 Common cspC cold shock-like protein cspC BU322 180 COG1278 CspC, Cold shock proteins Transcription 15616920 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase BU311 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 15617013 Common rpiA ribose-5-phosphate isomerase A BU411 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 15617113 Common rplV 50S ribosomal protein L22 BU519 228 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 15616667 Common rplK 50S ribosomal protein L11 BU038 245 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 15617056 Common mltA murein transglycosylase A BU458 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 15616929 Common zwf glucose-6-phosphate 1-dehydrogenase BU320 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 15616724 Common hisH imidazole glycerol phosphate synthase subunit HisH BU103 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 15616718 Common aroC chorismate synthase BU097 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 15616914 Common gpmA phosphoglycerate mutase BU304 152 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 15617106 Common rplE 50S ribosomal protein L5 BU512 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 15617172 Common yjeA lysyl-tRNA synthetase BU582 226 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15617091 Common fmt methionyl-tRNA formyltransferase BU497 221 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 15616957 Common acpP acyl carrier protein BU352 136 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15617020 Nonpathogen ygbQ hypothetical protein BU421 1 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 15616854 Common dnaE DNA polymerase III alpha chain BU238 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 15617123 Common rpsL 30S ribosomal protein S12 BU529 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 15616692 Common lig DNA ligase (NAD+) BU067 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15616673 Common argC N-acetyl-gamma-glutamyl-phosphate reductase BU048 215 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 15616962 Common ycfF hypothetical protein BU357 190 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15617029 Common dsbA thiol:disulfide interchange protein DsbA precursor BU430 35 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15616802 Common ung uracil-DNA glycosylase BU183 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 15616908 Common gapA glyceraldehyde 3-phosphate dehydrogenase A BU298 218 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15617163 Common mtlA PTS system mannitol-specific IIABC component BU572 72 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 15616969 Common uup ABC transporter ATP-binding protein Uup BU364 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15616903 Common bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase BU292 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 15617143 Common yggW hypothetical protein BU550 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15617192 Common engA GTP-binding protein EngA BU607 231 COG1160 COG1160, Predicted GTPases General function prediction only 28952055 Common yggB hypothetical protein BU452 199 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15617001 Common rplS 50S ribosomal protein L19 BU397 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 15616684 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase BU059 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 15616797 Common nrdB ribonucleotide-diphosphate reductase subunit beta BU178 153 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 15617153 Common rplI 50S ribosomal protein L9 BU562 214 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 15617068 Common cyoC cytochrome O ubiquinol oxidase subunit III BU470 77 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 15617083 Common folD methenyltetrahydrofolate cyclohydrolase BU486 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 15616973 Common argF ornithine carbamoyltransferase chain F BU368 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 15616926 Common znuB high-affinity zinc uptake system membrane protein ZnuB BU317 183 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15616980 Common truB tRNA pseudouridine 55 synthase BU375 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 15616653 Common ftsY cell division protein FtsY BU024 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 15617071 Common bolA BolA protein BU473 39 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 15616773 Common dnaK DnaK protein BU153 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15616842 Common ilvH acetolactate synthase small subunit BU225 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 15616755 Common glyS glycyl-tRNA synthetase beta chain BU135 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 15616886 Common yciB hypothetical protein BU275 72 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 15617040 Common yleA hypothetical protein BU441 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15617035 Common prfB peptide chain release factor 2 BU436 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 15617050 Common fba fructose-bisphosphate aldolase BU451 170 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15616648 Common groEL chaperonin GroEL BU019 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15616760 Common surA survival protein SurA precursor BU140 105 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15616867 Common acpS holo-[acyl-carrier protein] synthase BU256 140 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 15617185 Common ilvC ketol-acid reductoisomerase BU599 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 15617133 Common aroK shikimate kinase I BU539 201 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 15616794 Common ackA acetate kinase BU175 162 COG0282 ackA, Acetate kinase Energy production and conversion 15617047 Common asd aspartate-semialdehyde dehydrogenase BU448 196 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15616699 Nonpathogen fliJ flagellar FliJ protein BU077 1 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15616818 Common truA tRNA pseudouridine synthase A BU199 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 15616741 Common tyrS tyrosyl-tRNA synthetase BU121 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15616934 Common minE cell division topological specificity factor MinE BU325 74 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 15616828 Common speE spermidine synthase BU209 118 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 15617060 Common ribD2 riboflavin reductase BU462 137 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 15616748 Common rplT 50S ribosomal protein L20 BU128 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 15616912 Common kgd alpha-ketoglutarate decarboxylase BU302 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 15616733 Common rnfA hypothetical protein BU113 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 15616995 Common rplM 50S ribosomal protein L13 BU391 222 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 15616662 Common rpoC DNA-directed RNA polymerase subunit beta' BU033 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15616951 Common flgJ flagellar protein FlgJ BU345 28 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 15616766 Common dapB dihydrodipicolinate reductase BU146 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 15616878 Common ychE hypothetical protein BU267 155 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 15616726 Common hisF imidazole glycerol phosphate synthase subunit HisF BU105 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 15616737 Common rnfG nitrogen fixation protein BU117 51 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 15617017 Common nlpD lipoprotein NlpD precursor BU418 139 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15616959 Common holB DNA polymerase III delta' subunit BU354 198 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 15616716 Common dapE succinyl-diaminopimelate desuccinylase BU095 209 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15617098 Common secY preprotein translocase subunit SecY BU504 216 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 15617170 Common ibpA 16 kDa heat shock protein A BU580 67 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 15617042 Common ybeX hypothetical protein BU443 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 15616759 Common yabI hypothetical protein BU139 147 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15617066 Common cyoE protohaeme IX farnesyltransferase BU468 170 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 15617075 Common lon ATP-dependent protease LA BU477 217 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 15616975 Common pyrI aspartate carbamoyltransferase regulatory subunit BU370 61 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 15616881 Common pyrF orotidine 5'-phosphate decarboxylase BU270 164 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 15616834 Common murG UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase BU216 206 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15617059 Common ribD1 riboflavin deaminase BU461 202 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 15617125 Common yheM hypothetical protein BU531 28 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 15616671 Common metF 5,10-methylenetetrahydrofolate reductase BU046 139 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 15616924 Common infA translation initiation factor IF-1 BU315 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 15616752 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase BU132 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 15616792 Common ychA putative transcriptional regulator BU173 49 COG2912 COG2912, Uncharacterized conserved protein Function unknown 15616896 Common suhB extragenic suppressor protein SuhB BU285 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 15616804 Common yfjB hypothetical protein BU185 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 15616965 Common asnC asparaginyl-tRNA synthetase BU360 191 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15616689 Common ptsI phosphoenolpyruvate-protein phosphotransferase BU064 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 28952053 Common hflB cell division protein FtsH BU382 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15616747 Common rpmI 50S ribosomal protein L35 BU127 131 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 15616942 Common flgA flagella basal-body P-ring formation protein FlgA precursor BU336 26 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 15617151 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase BU560 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 15617104 Common rpsH 30S ribosomal protein S8 BU510 223 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 15617004 Common fis factor-for-inversion stimulation protein BU400 95 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 15616694 Common fliE flagellar hook-basal body complex protein FliE BU072 62 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 15617033 Common gmk guanylate kinase BU434 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 15616884 Common cls cardiolipin synthetase BU273 147 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15616849 Common pyrH uridylate kinase BU233 239 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 15616715 Common tktB transketolase BU094 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15617085 Common ybeD hypothetical protein BU488 24 COG2921 COG2921, Uncharacterized conserved protein Function unknown 15617052 Common recC exodeoxyribonuclease V 125 kDa polypeptide BU453 64 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 15617065 Common yccK hypothetical protein BU467 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 15616949 Common flgH flagellar basal body L-ring protein BU343 97 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 15616776 Common nuoCD bifunctional NADH:ubiquinone oxidoreductase subunit C/D BU156 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 15616775 Common nuoB NADH dehydrogenase subunit B BU155 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 15616866 Common yfhC hypothetical protein YfhC BU255 211 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 28952060 Common dapF diaminopimelate epimerase BU589 193 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 15617169 Common hslU ATP-dependent protease ATP-binding subunit BU579 212 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 15616993 Common obgE GTPase ObgE BU389 248 COG0536 Obg, Predicted GTPase General function prediction only 15616789 Common ychB hypothetical protein BU170 180 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 15616708 Common rpmB 50S ribosomal protein L28 BU086 136 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 15616780 Common nuoH NADH dehydrogenase subunit H BU160 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 15617110 Common rpmC 50S ribosomal protein L29 BU516 74 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 15616643 Common rpmH 50S ribosomal protein L34 BU013 186 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 15616840 Common ftsI cell division protein FtsI BU222 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15616750 Common pheT phenylalanyl-tRNA synthetase beta chain BU130 235 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 15616757 Common nfo endonuclease IV BU137 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 15617073 Common clpP ATP-dependent Clp protease proteolytic subunit BU475 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15616677 Common yibN hypothetical protein BU052 61 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15616658 Common cof Cof protein BU029 32 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15616731 Common mesJ cell cycle protein MesJ BU110 183 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15617049 Common pgk phosphoglycerate kinase BU450 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 15616816 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase BU197 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 15616814 Common hpt hypoxanthine phosphoribosyltransferase BU195 149 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 15616836 Common murD UDP-N-acetylmuramoylalanine-D-glutamate ligase BU218 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15617141 Common yqgF hypothetical protein BU548 131 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 15616822 Common yacE hypothetical protein BU203 159 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism