Treponema pallidum subsp. pallidum str. Nichols, complete genome NC_000919 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 15639689 Common - hypothetical protein TP0702 185 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15639580 Common - hypothetical protein TP0592 11 None None None 15639944 Common flgG flagellar basal body rod protein FlgG TP0960 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15639128 Pathogen - hypothetical protein TP0134 1 None None None 15639137 Common - thiamine ABC transporter, permease protein, putative TP0143 68 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 15639396 Common - mcbG protein, putative TP0405 19 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 15639125 Pathogen - tpr protein D (tprD) TP0131 1 None None None 15639853 Common - flagellar filament 34.5 kDa core protein (flaB1) TP0868 120 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15639909 Common - tex protein (tex) TP0924 201 COG2183 Tex, Transcriptional accessory protein Transcription 15639048 Common - hypothetical protein TP0054 208 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15639218 Pathogen - hypothetical protein TP0226 1 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15639112 Pathogen - hypothetical protein TP0118 1 None None None 15639373 Pathogen - hypothetical protein TP0382 1 None None None 15639512 Common - hypothetical protein TP0522 5 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 15639575 Pathogen - hypothetical protein TP0587 1 None None None 15639771 Pathogen - hypothetical protein TP0784 1 None None None 15639962 Common lspA signal peptidase II TP0978 55 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15639076 Common - formate hydrogenlyase transcriptional activator (fhlA) TP0082 168 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 15639369 Pathogen - flagellar protein, putative TP0378 1 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 15639172 Pathogen - hypothetical protein TP0179 2 None None None 15639354 Common - chemotaxis histidine kinase (cheA) TP0363 148 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 15639892 Pathogen - hypothetical protein TP0907 2 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 15639017 Common - sodium- and chloride- dependent transporter TP0023 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 15639902 Common - Mg2+ transport protein (mgtE) TP0917 175 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 15639877 Common nusA transcription elongation factor NusA TP0892 229 COG0195 NusA, Transcription elongation factor Transcription 15639519 Common - V-type ATP synthase subunit A TP0529 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 15640015 Pathogen - tpr protein L (tprL) TP1031 1 None None None 15639146 Common - hypothetical protein TP0153 24 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 15639303 Pathogen - hypothetical protein TP0311 1 None None None 15639251 Common - hypothetical protein TP0259 2 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 15639188 Common rpsC 30S ribosomal protein S3 TP0195 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 15639587 Pathogen - hypothetical protein TP0599 1 None None None 15639598 Pathogen - tpr protein H (tprH) TP0610 1 None None None 15639530 Common era GTP-binding protein Era TP0541 219 COG1159 Era, GTPase General function prediction only 15639509 Common - hypothetical protein TP0518 42 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 15639971 Pathogen - hypothetical protein TP0987 1 None None None 15639664 Pathogen - hypothetical protein TP0677 1 None None None 15639298 Common rpsD 30S ribosomal protein S4 TP0306 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15639103 Common - rRNA methylase, putative TP0109 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15639387 Common - flagellar basal-body rod protein (flgB) TP0396 48 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 15639618 Common - chemotaxis protein methyltransferase (cheR) TP0630 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 15639205 Common - DNA-directed RNA polymerase subunit alpha TP0212 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 15639950 Pathogen - hypothetical protein TP0966 1 None None None 15639450 Common - hypothetical protein TP0459 197 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15639310 Common - membrane lipoprotein (tmpC) TP0319 88 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 15639088 Common - phosphate acetyltransferase (pta) TP0094 161 COG0280 Pta, Phosphotransacetylase Energy production and conversion 15639346 Pathogen - hypothetical protein TP0355 1 None None None 15639065 Common - ATP-dependent Clp protease subunit B (clpB) TP0071 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15639341 Common - glutamate-5-semialdehyde dehydrogenase (proA) TP0350 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 15639529 Common - anti-sigma F factor antagonist (spoIIAA-2) TP0540 61 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 15639038 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA TP0044 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15639629 Common - phosphomannomutase (manB) TP0642 213 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15639522 Common - V-type ATPase, subunit I (atpI-2) TP0533 20 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 15639478 Pathogen - hypothetical protein TP0487 1 None None None 15639922 Common - hypothetical protein TP0937 31 COG0622 COG0622, Predicted phosphoesterase General function prediction only 15639372 Pathogen - hypothetical protein TP0381 2 COG5522 COG5522, Predicted integral membrane protein Function unknown 15639211 Common - sigma factor SigG regulation protein, putative TP0219 91 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 15639568 Common - hypothetical protein TP0580 145 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15639263 Common - chromosome partitioning protein (parB) TP0271 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 15639764 Pathogen - hypothetical protein TP0777 1 COG1656 COG1656, Uncharacterized conserved protein Function unknown 15639071 Common - capsular polysaccharide biosynthesis protein (cap5D) TP0077 184 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15639258 Pathogen - hypothetical protein TP0266 1 None None None 15639645 Common - flagellar assembly protein FliW TP0658 41 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 15639055 Common rpsR 30S ribosomal protein S18 TP0061 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 15639500 Common - alkyl hydroperoxide reductase (ahpC) TP0509 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15639803 Common - enolase (eno) TP0817 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 15639732 Common rplU 50S ribosomal protein L21 TP0745 210 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 15639636 Common - hemolysin (tlyC) TP0649 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15639471 Pathogen - hypothetical protein TP0480 1 None None None 15639844 Pathogen - hypothetical protein TP0858 1 None None None 15639829 Common - heat shock protein, putative TP0843 173 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15639401 Common secD preprotein translocase subunit SecD TP0410 220 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 15639870 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) TP0885 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 15639884 Pathogen - hypothetical protein TP0899 1 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 15639480 Common - hypothetical protein TP0489 33 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 15639446 Pathogen - hypothetical protein TP0455 2 None None None 15639015 Pathogen - hypothetical protein TP0021 1 None None None 15639740 Pathogen - hypothetical protein TP0753 1 None None None 15639001 Pathogen - Tp75 protein TP0006 1 None None None 15639916 Common - hypothetical protein TP0931 10 COG1626 TreA, Neutral trehalase Carbohydrate transport and metabolism 15639880 Common - hypothetical protein TP0895 21 COG3439 COG3439, Uncharacterized conserved protein Function unknown 15639141 Pathogen - hypothetical protein TP0148 1 None None None 15639557 Common - 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase (eda) TP0568 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 15639247 Common rpmE 50S ribosomal protein L31 TP0255 171 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15639752 Common - cell division protein (ftsH) TP0765 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15639734 Pathogen - hypothetical protein TP0747 1 None None None 15639186 Common rpsS 30S ribosomal protein S19 TP0193 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 15639230 Common rplA 50S ribosomal protein L1 TP0238 216 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 15639541 Pathogen - hypothetical protein TP0552 1 None None None 15639025 Pathogen - hypothetical protein TP0031 1 None None None 15639915 Pathogen - hypothetical protein TP0930 3 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15639796 Common - ribonuclease III (rnc) TP0809 214 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 15639999 Common nusB transcription antitermination protein NusB TP1015 194 COG0781 NusB, Transcription termination factor Transcription 15639330 Common - hypothetical protein TP0339 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15639654 Common - uridine kinase (udk) TP0667 72 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 15639571 Pathogen - hypothetical protein TP0583 1 None None None 15639228 Common - transcription antitermination protein (nusG) TP0236 214 COG0250 NusG, Transcription antiterminator Transcription 15639419 Common - V-type ATP synthase subunit D TP0428 13 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 15639984 Pathogen - hypothetical protein TP1000 1 None None None 15639550 Common - hypothetical protein TP0561 85 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 15639273 Pathogen - hypothetical protein TP0281 1 None None None 15639603 Common - nitrogen fixation protein (nifU) TP0615 91 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 15639195 Common rpsN 30S ribosomal protein S14 TP0202 207 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 15639514 Common - ATP-dependent protease LA (lon-2) TP0524 210 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 15639493 Common - hypothetical protein TP0502 81 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 15639008 Pathogen - hypothetical protein TP0014 2 None None None 15639339 Common - hypothetical protein TP0348 22 COG4769 COG4769, Predicted membrane protein Function unknown 15639741 Common - hypothetical protein TP0754 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15639221 Common - DNA polymerase, bacteriophage-type TP0229 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 15639166 Pathogen - hypothetical protein TP0173 1 None None None 15639307 Pathogen - hypothetical protein TP0315 1 None None None 15639499 Common clpX ATP-dependent protease ATP-binding subunit TP0508 220 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 15639779 Common - flagellar filament 33 kDa core protein (flaB2) TP0792 119 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15639412 Common - hypothetical protein TP0421 29 COG3391 COG3391, Uncharacterized conserved protein Function unknown 15639139 Common - long-chain-fatty-acid--CoA ligase TP0145 212 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 15639834 Common rplT 50S ribosomal protein L20 TP0848 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 15639726 Common - hypothetical protein TP0739 7 COG1316 LytR, Transcriptional regulator Transcription 15639326 Pathogen - hypothetical protein TP0335 1 None None None 15639690 Pathogen - hypothetical protein TP0703 1 None None None 15639368 Pathogen - hypothetical protein TP0377 1 None None None 15639672 Common - methylgalactoside ABC transporter, ATP binding protein (mglA) TP0685 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 15639990 Common - DNA gyrase, subunit B (gyrB) TP1006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15639817 Common argS arginyl-tRNA synthetase TP0831 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639969 Common aspS aspartyl-tRNA synthetase TP0985 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639788 Common - ATP-dependent Clp protease subunit A (clpA) TP0801 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15639703 Common - flagellar biosynthetic protein (fliR) TP0716 101 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 15639535 Common - periplasmic serine protease, putative TP0546 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15639687 Pathogen - hypothetical protein TP0700 1 None None None 15639624 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase TP0637 212 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 15639202 Common rpmJ 50S ribosomal protein L36 TP0209 133 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 15639110 Common - excinuclease ABC subunit B TP0116 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 15639698 Pathogen - hypothetical protein TP0711 2 None None None 15639427 Common - hypothetical protein TP0436 83 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 15639831 Common - P23 protein, putative TP0845 83 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 15639274 Pathogen - hypothetical protein TP0282 1 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 15639466 Common pgi glucose-6-phosphate isomerase TP0475 193 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 15639321 Common - cell division protein, putative TP0330 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15639105 Common - RNA polymerase sigma-54 factor (rpoN) TP0111 143 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 15640017 Common - hypothetical protein TP1033 126 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 15639894 Common rplS 50S ribosomal protein L19 TP0909 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 15639596 Pathogen - hypothetical protein TP0608 1 None None None 15639144 Pathogen - hypothetical protein TP0151 1 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 15639488 Common - rod shape-determining protein (mreB) TP0497 179 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 15639784 Common - 1-pyrroline-5-carboxylate reductase (proC) TP0797 210 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 15639265 Pathogen - hypothetical protein TP0273 1 None None None 15639992 Common - ribonucleotide-diphosphate reductase subunit alpha TP1008 215 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15639719 Common - methylenetetrahydrofolate dehydrogenase (folD) TP0732 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 15639381 Common - cell division protein FtsZ TP0390 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 15639034 Common - methyl-accepting chemotaxis protein (mcp1) TP0040 143 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15639875 Common - ribosome-binding factor A (rbfA) TP0890 114 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 15639291 Pathogen - hypothetical protein TP0299 1 None None None 15639978 Common - hypothetical protein TP0994 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15639213 Common - D,D-carboxypeptidase, putative TP0221 38 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15639886 Common - hypothetical protein TP0901 135 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15639631 Common lysK lysyl-tRNA synthetase TP0644 79 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 15639224 Pathogen - hypothetical protein TP0232 1 None None None 15639403 Common - hypothetical protein TP0412 5 None None None 15639773 Common - ABC transporter, ATP-binding protein, putative TP0786 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 15639046 Common - protoporphyrinogen oxidase (hemK) TP0052 199 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15639907 Pathogen - hypothetical protein TP0922 1 None None None 15639208 Common - grpE protein (grpE) TP0215 221 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15639380 Common - cell division protein (ftsA) TP0389 190 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15639900 Common - hypothetical protein TP0915 73 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 15639577 Common - phosphocarrier protein HPr (ptsH) TP0589 148 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 15639081 Common - hypothetical protein TP0087 76 COG1430 COG1430, Uncharacterized conserved protein Function unknown 15639531 Common - diphosphate--fructose-6-phosphate 1-phosphotransferase TP0542 134 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 15639805 Common - ribonuclease Z TP0819 119 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 15639735 Pathogen - cytoplasmic filament protein A (cfpA) TP0748 1 None None None 15639743 Common - methionyl-tRNA formyltransferase (fmt) TP0756 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 15639086 Common - RNA polymerase sigma-24 factor (rpoE) TP0092 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 15639485 Common - hypothetical protein TP0494 38 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 15639960 Pathogen - hypothetical protein TP0976 1 None None None 15639135 Common - methylated-DNA-protein-cysteine S-methyltransferase (dat) TP0141 210 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 15639236 Common - 30S ribosomal protein S7 TP0244 221 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 15639356 Common - chemotaxis protein (cheX) TP0365 27 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 15639863 Pathogen - hypothetical protein TP0878 1 None None None 15639122 Pathogen - hypothetical protein TP0128 1 None None None 15639942 Common - dicarboxylate transporter (dctM) TP0958 120 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 15639562 Pathogen - hypothetical protein TP0573 1 None None None 15639924 Common - pyruvate oxidoreductase TP0939 127 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15639476 Common - adenylate cyclase TP0485 94 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 15639059 Common - hypothetical protein TP0065 201 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 15639285 Pathogen - hypothetical protein TP0293 1 None None None 15639677 Pathogen - hypothetical protein TP0690 1 None None None 15639159 Common - ABC transporter, permease protein (troD) TP0166 130 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15639410 Common - survival protein, putative TP0419 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 15639248 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA) TP0256 188 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15639824 Common - ABC transporter, ATP-binding protein TP0838 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15639053 Pathogen - hypothetical protein TP0059 1 None None None 15639116 Common - phosphoenolpyruvate carboxykinase TP0122 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 15639524 Pathogen - hypothetical protein TP0535 1 None None None 15639441 Common - elongation factor G TP0450 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15639647 Common flgK flagellar hook-associated protein FlgK TP0660 125 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 15639334 Common - A/G-specific adenine glycosylase, putative TP0343 201 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 15639569 Common - ABC transporter, ATP-binding protein TP0581 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15639362 Common - hypothetical protein TP0371 170 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 15639612 Common - hypothetical protein TP0624 107 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15639305 Pathogen - tpr protein E (tprE) TP0313 1 None None None 15639036 Common - hypothetical protein TP0042 2 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 15639981 Common - protease IV (sppA) TP0997 168 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15639405 Common - D-alanine glycine permease (dagA) TP0414 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 15639819 Pathogen - hypothetical protein TP0833 1 None None None 15639336 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) TP0345 211 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15639241 Pathogen - flagellar filament outer layer protein (flaA-1) TP0249 2 None None None 15639223 Common - hypothetical protein TP0231 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15639798 Pathogen - hypothetical protein TP0811 1 None None None 15639184 Common rplW 50S ribosomal protein L23 TP0191 207 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 15639432 Common - hypothetical protein TP0441 230 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 15639398 Common - phosphoglycolate phosphatase (gph-1) TP0407 33 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15639861 Common - hypothetical protein TP0876 94 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 15639261 Common - hypothetical protein TP0269 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15639718 Common - hypothetical protein TP0731 106 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15640009 Common rplM 50S ribosomal protein L13 TP1025 223 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 15640024 Common - lysyl-tRNA synthetase (lysS-2) TP1040 203 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15639239 Common - N-acetylmuramoyl-L-alanine amidase (amiA) TP0247 175 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15639555 Common - alginate O-acetylation protein (algI) TP0566 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 15639842 Pathogen - hypothetical protein TP0856 1 None None None 15639601 Common - hypothetical protein TP0613 153 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 15639956 Common - hypothetical protein TP0972 79 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 15639257 Common - amino acid ABC transporter, permease protein (braC) TP0265 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 15639094 Common - thioredoxin, putative TP0100 168 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 15639652 Common - hypothetical protein TP0665 3 None None None 15639607 Pathogen - hypothetical protein TP0619 1 None None None 15639858 Pathogen - hypothetical protein TP0873 1 None None None 15639417 Common - V-type ATP synthase subunit A TP0426 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 15639581 Pathogen - hypothetical protein TP0593 1 None None None 15639439 Common - uracil phosphoribosyltransferase, putative TP0448 156 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 15639063 Pathogen - hypothetical protein TP0069 1 None None None 15639812 Common - hypothetical protein TP0826 68 COG1624 COG1624, Uncharacterized conserved protein Function unknown 15639154 Pathogen - hypothetical protein TP0161 1 None None None 15639044 Common - hypothetical protein TP0050 8 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 15639639 Common - spermidine/putrescine ABC transporter, ATP-binding protein (potA) TP0652 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15639782 Pathogen - hypothetical protein TP0795 1 None None None 15639801 Common - hypothetical protein TP0815 7 COG3393 COG3393, Predicted acetyltransferase General function prediction only 15639100 Common - carnitine transporter, putative TP0106 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 15639640 Common - spermidine/putrescine ABC transporter, permease protein (potB) TP0653 165 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 15639543 Common - phosphoglycolate phosphatase (gph-2) TP0554 159 COG0546 Gph, Predicted phosphatases General function prediction only 15639701 Common flhA flagellar biosynthesis protein A TP0714 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 15639696 Common - RNA polymerase sigma factor WhiG TP0709 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15639679 Common - recA protein (recA) TP0692 223 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 15639429 Common - hypothetical protein TP0438 236 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 15640010 Common - oligoendopeptidase F, putative TP1026 35 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 15639997 Common groES co-chaperonin GroES TP1013 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 15639537 Pathogen - hypothetical protein TP0548 1 None None None 15639495 Pathogen - hypothetical protein TP0504 1 None None None 15639200 Common rplO 50S ribosomal protein L15 TP0207 211 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 15639720 Pathogen - hypothetical protein TP0733 1 None None None 15639849 Common - nitrogen fixation protein (nifS-2) TP0863 223 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 15639097 Common - ATP-dependent DNA helicase, putative TP0103 201 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 15639006 Pathogen - hypothetical protein TP0012 1 None None None 15639573 Common - oligopeptide ABC transporter, periplasmic binding protein (oppA) TP0585 160 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 15639709 Pathogen fliL flagellar basal body-associated protein FliL TP0722 2 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 15639967 Pathogen - hypothetical protein TP0983 1 None None None 15639267 Common - UDP-N-acetyl-D-mannosamine transferase, putative TP0275 32 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 15639890 Common - ribosomal protein S16 (rpsP) TP0905 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 15639790 Pathogen - hypothetical protein TP0803 1 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 15640002 Common - hypothetical protein TP1018 77 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 15639918 Common - UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (murE) TP0933 208 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15639375 Common - hypothetical protein TP0384 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 15639281 Common - hypothetical protein TP0289 13 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 15639626 Common - methyl-accepting chemotaxis protein (mcp2-2) TP0639 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15639164 Common - lipoprotein, 15 kDa (tpp15) TP0171 11 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 15639713 Common - flagellar protein (flbD) TP0726 20 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 15639319 Common - DNA mismatch repair protein TP0328 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15639515 Common - translation elongation factor P (efp) TP0525 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15639728 Common - hypothetical protein TP0741 162 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 15639754 Common - elongation factor G TP0767 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15639021 Common - hemolysin, putative TP0027 215 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15639309 Pathogen - hypothetical protein TP0318 1 None None None 15640001 Common - alanyl-tRNA synthetase TP1017 248 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15640008 Common rpsI 30S ribosomal protein S9 TP1024 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 15639449 Common - hypothetical protein TP0458 139 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 15639680 Pathogen - hypothetical protein TP0693 1 None None None 15639074 Common - quinoline 2-oxidoreductase TP0080 115 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 15639712 Common - flagellar motor rotation protein (motA) TP0725 104 COG1291 MotA, Flagellar motor component Cell motility and secretion 15639114 Common - amino acid ABC transporter, ATP-binding protein (abc) TP0120 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 15639364 Common - hypothetical protein TP0373 214 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15639342 Common - gamma-glutamyl kinase TP0351 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 15639288 Common - hypothetical protein TP0296 65 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 15639421 Pathogen - V-type ATP synthase subunit K TP0430 2 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 15639839 Common - ATP-binding protein (ylxH-2) TP0853 209 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15639199 Common rpsE 30S ribosomal protein S5 TP0206 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 161579587 Common smpB SsrA-binding protein TP0184 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 15639501 Common - GTP-binding protein LepA TP0510 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 15639457 Pathogen - hypothetical protein TP0466 1 None None None 15639985 Pathogen - hypothetical protein TP1001 1 None None None 15639526 Common - triosephosphate isomerase (tpi) TP0537 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 15640025 Common clpP ATP-dependent Clp protease proteolytic subunit TP1041 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15639442 Pathogen - hypothetical protein TP0451 1 None None None 15639287 Common - carhohydrate kinase (xylB) TP0295 24 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 15639056 Common - single-strand DNA binding protein (ssb) TP0062 208 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15639826 Pathogen - hypothetical protein TP0840 1 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15639642 Common - spermidine/putrescine ABC transporter, periplasmic binding protein (potD) TP0655 122 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 15639717 Common - hypothetical protein TP0730 17 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15639745 Common rpsU 30S ribosomal protein S21 TP0758 42 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 15639453 Pathogen - hypothetical protein TP0462 1 None None None 15639737 Pathogen - hypothetical protein TP0750 1 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 15639760 Common - periplasmic serine protease DO (htrA-1) TP0773 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15639533 Common - hypothetical protein TP0544 38 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 15639584 Common - polynucleotide adenylyltransferase (pcnB) TP0596 201 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15639822 Pathogen - hypothetical protein TP0836 1 None None None 15639649 Common - fructose-bisphosphate aldolase TP0662 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15639599 Common - ABC transporter, ATP-binding protein TP0611 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 15639940 Common - hypothetical protein TP0956 7 COG5660 COG5660, Predicted integral membrane protein Function unknown 15639975 Common - rubredoxin TP0991 106 COG1773 COG1773, Rubredoxin Energy production and conversion 15639020 Common - flagellar motor switch protein (fliG-1) TP0026 122 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 15639407 Common - signal recognition particle protein (ffh) TP0416 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 15639093 Common pyrH uridylate kinase TP0099 40 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 15639516 Common - ATP-dependent helicase (hrpA) TP0526 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 15639209 Common dnaK molecular chaperone DnaK TP0216 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15639949 Common - membrane fusion protein, putative TP0965 110 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15639806 Common - hypothetical protein TP0820 33 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 15639124 Pathogen - hypothetical protein TP0130 1 None None None 15639482 Common - hypothetical protein TP0491 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 15639544 Common - glutamate/ aspartate transporter, putative TP0555 125 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 15639294 Common - hypothetical protein TP0302 21 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 15639594 Common rpsB 30S ribosomal protein S2 TP0606 245 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 15639661 Pathogen - hypothetical protein TP0674 1 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 15639694 Pathogen - hypothetical protein TP0707 1 None None None 15639277 Common - hypothetical protein TP0285 4 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 15639108 Common - Lambda CII stability-governing protein (hflC) TP0114 118 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15639377 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (murF) TP0386 206 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 15639192 Common rplN 50S ribosomal protein L14 TP0199 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 15639358 Common - chromosome segregation protein, putative TP0367 205 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15639045 Common prfA peptide chain release factor 1 TP0051 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 15639317 Common - outer membrane protein TP0326 162 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 15639383 Common - hypothetical protein TP0392 4 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15639149 Common - hypothetical protein TP0156 73 COG0824 FcbC, Predicted thioesterase General function prediction only 15639029 Common - ABC transporter, ATP-binding protein TP0035 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 15639770 Pathogen - hypothetical protein TP0783 1 None None None 15639866 Common - ABC transporter, ATP-binding protein (natA) TP0881 249 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 15639896 Common - hypothetical protein TP0911 71 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 15639988 Common - recombination protein (recR) TP1004 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15639765 Common - mazG protein (mazG) TP0778 151 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 15639174 Pathogen - hypothetical protein TP0181 1 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 15639610 Common - hypothetical protein TP0622 2 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 15639484 Common - RNA polymerase sigma factor RpoD TP0493 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15639069 Common - sugar ABC transporter, permease protein (y4oQ) TP0075 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 15639954 Pathogen - hypothetical protein TP0970 1 None None None 15639668 Common - alanine racemase (alr) TP0681 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 15639351 Pathogen - hypothetical protein TP0360 1 None None None 15639659 Common - glycyl-tRNA synthetase TP0672 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15639469 Common - glucose-6-phosphate 1-dehydrogenase TP0478 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 15639545 Common - asparagine synthetase AsnA TP0556 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 15639650 Pathogen - outer membrane protein, putative TP0663 2 None None None 15639792 Common - exoribonuclease II (rnb) TP0805 179 COG0557 VacB, Exoribonuclease R Transcription 15639099 Common - DNA polymerase I (polA) TP0105 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 15639430 Common - purine-binding chemotaxis protein (cheW-2) TP0439 122 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15639136 Common - thiamine ABC transporter, ATP-binding protein, putative TP0142 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15639931 Common - glucose-inhibited division protein B (gidB) TP0946 182 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 15640006 Common - DNA repair protein RadA TP1022 220 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 15639722 Common - putative oxidoreductase TP0735 195 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 15639507 Common - virulence factor (mviN) TP0516 177 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 15639151 Common - hypothetical protein TP0158 19 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15639391 Common fliG flagellar motor switch protein G TP0400 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 15639911 Common - signal peptidase I, putative TP0926 47 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15639085 Common - cysteinyl-tRNA synthetase (cysS) TP0091 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639212 Common - anti-sigma F factor antagonist (spoIIAA-1) TP0220 16 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 15639683 Common - nicotinamidase, putative TP0696 28 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 15639973 Common - P26 TP0989 4 None None None 15639707 Common - flagellar motor switch protein (fliY) TP0720 124 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 15639887 Common - carboxylesterase (est) TP0902 40 COG1647 COG1647, Esterase/lipase General function prediction only 15639462 Common - hypothetical protein TP0471 23 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15639423 Pathogen - hypothetical protein TP0432 1 None None None 15639018 Common - hypothetical protein TP0024 82 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15639804 Pathogen - hypothetical protein TP0818 1 None None None 15639776 Common - hypothetical protein TP0789 29 None None None 15639847 Common - glucosamine-fructose-6-phosphate aminotransferase (glmS) TP0861 237 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 15639269 Common - carboxyl-terminal protease (ctp) TP0277 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 15639789 Pathogen - hypothetical protein TP0802 1 None None None 15640027 Pathogen - RNAse P, protein component TP0950a 3 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 15638999 Pathogen - hypothetical protein TP0004 1 None None None 15639965 Common - sensory transduction histidine kinase, putative TP0981 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 15639810 Common - 1-deoxy-D-xylulose-5-phosphate synthase TP0824 224 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 15639041 Common - hypothetical protein TP0047 7 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 15639926 Pathogen - hypothetical protein TP0941 1 None None None 15639051 Common - oxaloacetate decarboxylase, subunit beta (oadB) TP0057 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 15639715 Common flgD flagellar basal body rod modification protein TP0728 78 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 15639605 Pathogen - hypothetical protein TP0617 1 None None None 15639553 Pathogen - hypothetical protein TP0564 1 None None None 15639682 Common - phosphoribosylglycinamide formyltransferase, putative TP0695 28 COG0439 AccC, Biotin carboxylase Lipid metabolism 15639912 Pathogen - hypothetical protein TP0927 1 None None None 15639235 Common rpsL 30S ribosomal protein S12 TP0243 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 15639304 Common - hypothetical protein TP0312 25 COG2035 COG2035, Predicted membrane protein Function unknown 15639243 Common - DNA-binding protein II TP0251 115 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15639032 Common - regulatory protein (pfoS/R) TP0038 13 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 15639434 Pathogen - hypothetical protein TP0443 3 None None None 15639292 Common - ribose/galactose ABC transporter, ATP-binding protein (rbsA-1) TP0300 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 15639322 Common - 6-phosphogluconate dehydrogenase TP0331 176 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 15639011 Pathogen - hypothetical protein TP0017 3 None None None 15639189 Common rplP 50S ribosomal protein L16 TP0196 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 15639873 Common - riboflavin kinase/FMN adenylyltransferase (ribF) TP0888 134 COG0196 RibF, FAD synthase Coenzyme metabolism 15639255 Common - hypothetical protein TP0263 5 None None None 15639756 Pathogen - outer membrane protein (tmpB) TP0769 2 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 15640020 Common - cation-transporting ATPase, P-type TP1036 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15639520 Pathogen - V-type ATPase, subunit E, putative TP0530 1 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 15639229 Common rplK 50S ribosomal protein L11 TP0237 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 15639821 Common - ankyrin, putative TP0835 97 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 15639518 Common - V-type ATP synthase subunit B TP0528 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 15639459 Common - hypothetical protein TP0468 77 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15639444 Pathogen - hypothetical protein TP0453 1 None None None 15639043 Common - hypothetical protein TP0049 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15639472 Common - hypothetical protein TP0481 4 None None None 15639767 Common nadE NAD synthetase TP0780 171 COG0171 NadE, NAD synthase Coenzyme metabolism 15639455 Common - hypothetical protein TP0464 170 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 15639928 Common - flagellar protein (fliS) TP0943 62 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15639673 Common - methylgalactoside ABC transporter, permease protein (mglC) TP0686 126 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 15639747 Common - penicillin-binding protein (pbp-3) TP0760 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15639828 Common - methionine aminopeptidase (map) TP0842 245 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 15639616 Common - nicotinate phosphoribosyltransferase TP0628 100 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 15639785 Common metG methionyl-tRNA synthetase TP0798 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639666 Pathogen - hypothetical protein TP0679 1 None None None 15639528 Pathogen - hypothetical protein TP0539 1 None None None 15639130 Pathogen - hypothetical protein TP0136 1 None None None 15639937 Common - pheromone shutdown protein (traB) TP0953 38 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 15639072 Common - spore coat polysaccharide biosynthesis protein (spsC) TP0078 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15639207 Pathogen - hypothetical protein TP0214 1 None None None 15639602 Common - nitrogen fixation protein (nifS-1) TP0614 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15639730 Common rpmA 50S ribosomal protein L27 TP0743 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 15639436 Common - 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme (thiJ) TP0445 51 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15639400 Pathogen - hypothetical protein TP0409 1 None None None 15639338 Pathogen - hypothetical protein TP0347 1 None None None 15639370 Common secA preprotein translocase subunit SecA TP0379 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 161579585 Common - HPr kinase/phosphorylase TP0591 66 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 15639300 Common - amino acid ABC transporter, periplasmic binding protein (hisJ) TP0308 85 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15639634 Common - seryl-tRNA synthetase TP0647 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639170 Common - hypothetical protein TP0177 2 None None None 15639761 Common - Mg2+ transport protein (mgtC) TP0774 118 COG1285 SapB, Uncharacterized membrane protein Function unknown 15639333 Common - cytidylate kinase TP0342 37 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 15639296 Pathogen - hypothetical protein TP0304 1 None None None 15639217 Common - leucine-rich repeat protein TpLRR TP0225 11 None None None 15639386 Common - integrase/recombinase (xprB) TP0395 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15639536 Common - penicillin tolerance protein (lytB) TP0547 179 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 15639379 Common - cell division protein (ftsQ) TP0388 5 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 15639898 Common - hypothetical protein TP0913 134 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 15639780 Pathogen - hypothetical protein TP0793 1 None None None 15639101 Common - licC protein (licC) TP0107 69 COG4750 LicC, CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes Cell envelope biogenesis, outer membrane 15639425 Pathogen - hypothetical protein TP0434 1 None None None 15639147 Common - hypothetical protein TP0154 177 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15639156 Common - ABC transporter, periplasmic binding protein (troA) TP0163 162 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15639348 Common - biotin--acetyl-CoA-carboxylase ligase (birA) TP0357 168 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 15639030 Common - ABC transporter, permease protein TP0036 184 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15639934 Common - putative inner membrane protein translocase component YidC TP0949 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 15639903 Pathogen - hypothetical protein TP0918 1 COG0170 SEC59, Dolichol kinase Lipid metabolism 15639851 Pathogen - hypothetical protein TP0865 1 None None None 15639367 Pathogen - hypothetical protein TP0376 1 None None None 15639126 Pathogen - hypothetical protein TP0132 1 None None None 15639161 Common - phosphoglycerate mutase (pgm) TP0168 167 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 15639592 Common - ribosome recycling factor TP0604 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 15639855 Common - flagellar filament 31 kDa core protein (flaB3) TP0870 120 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15640012 Common - DNA helicase II (uvrD) TP1028 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15639947 Common - hypothetical protein TP0963 174 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 15639808 Common - hypothetical protein TP0822 191 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15639091 Common - translation initiation factor 1 (infA) TP0097 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 15639083 Common - cyclic nucleotide binding protein TP0089 44 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15639078 Pathogen - hypothetical protein TP0084 1 None None None 15639505 Common - excinuclease ABC, subunit A (uvrA) TP0514 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 15639232 Common rplL 50S ribosomal protein L7/L12 TP0240 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 15639778 Pathogen - hypothetical protein TP0791 1 None None None 15639016 Pathogen - hypothetical protein TP0022 1 None None None 15639705 Common fliP flagellar biosynthesis protein FliP TP0718 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 15639702 Common flhB flagellar biosynthesis protein FlhB TP0715 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 15639464 Pathogen - hypothetical protein TP0473 1 None None None 15639868 Common - hypothetical protein TP0883 26 COG0795 COG0795, Predicted permeases General function prediction only 15639963 Common - hypothetical protein TP0979 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15639566 Common - cell division protein (ftsY) TP0578 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 15639993 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase TP1009 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15639832 Pathogen - hypothetical protein TP0846 1 None None None 15639491 Common - penicillin-binding protein (pbp-1) TP0500 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15639675 Common - immunity protein (mccF) TP0688 80 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 15639724 Common - sugar ABC transporter, periplasmic binding protein (msmE) TP0737 24 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15639979 Common - cyclic nucleotide binding protein TP0995 14 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15639187 Common rplV 50S ribosomal protein L22 TP0194 196 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 15639547 Common - hypothetical protein TP0558 13 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 15639365 Pathogen - hypothetical protein TP0374 1 None None None 15639794 Common rpmF 50S ribosomal protein L32 TP0807 9 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 15639889 Pathogen - hypothetical protein TP0904 1 None None None 15639215 Common - hypothetical protein TP0223 66 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15639393 Common - flagellum-specific ATP synthase (fliI) TP0402 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 15639540 Common - phosphatase TP0551 24 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15640019 Common valS valyl-tRNA synthetase TP1035 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639168 Common - hypothetical protein TP0175 4 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15639951 Pathogen - hypothetical protein TP0967 1 None None None 15639134 Common - K+ transport protein (ntpJ) TP0140 133 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15639271 Common - bifunctional cytidylate kinase/ribosomal protein S1 TP0279 223 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 15639496 Common - hexokinase (hxk) TP0505 6 COG5026 COG5026, Hexokinase Carbohydrate transport and metabolism 15639111 Pathogen - tpr protein C (tprC) TP0117 1 None None None 15639621 Common - bifunctional methionine sulfoxide reductase B/A protein TP0633 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15639692 Common - penicillin-binding protein (pbp-2) TP0705 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 15640004 Common - glu-tRNA amidotransferase, subunit A (gatA) TP1020 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 15639315 Pathogen - hypothetical protein TP0324 1 None None None 15639182 Common rplC 50S ribosomal protein L3 TP0189 242 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 15639750 Pathogen - hypothetical protein TP0763 1 None None None 15639158 Common - ABC transporter, permease protein (troC) TP0165 40 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15639815 Common - hypothetical protein TP0829 6 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 15640022 Common - bacterioferrin (TpF1) TP1038 124 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 15639067 Common - hypothetical protein TP0073 60 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 15639685 Pathogen - hypothetical protein TP0698 1 None None None 15639023 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase TP0029 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 15639731 Common - hypothetical protein TP0744 3 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 15639259 Common - hypothetical protein TP0267 45 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 15639193 Common rplX 50S ribosomal protein L24 TP0200 204 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 15639559 Common - hypothetical protein TP0570 48 COG3762 COG3762, Predicted membrane protein Function unknown 15639474 Pathogen - hypothetical protein TP0483 1 None None None 15639570 Common - hypothetical protein TP0582 137 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15639921 Common - hemolysin, putative TP0936 204 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15639758 Common - hypothetical protein TP0771 89 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 15639060 Pathogen - hypothetical protein TP0066 1 None None None 15638997 Common - DNA polymerase III, subunit beta (dnaN) TP0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 15640029 Common rpsT 30S ribosomal protein S20 TP0250a 2 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 15639278 Pathogen - hypothetical protein TP0286 1 None None None 15639882 Pathogen - tpr protein K (tprK) TP0897 1 None None None 15639003 Pathogen - hypothetical protein TP0008 1 None None None 15639551 Common - spore coat polysaccharide biosynthesis protein (spsE) TP0562 76 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 15639841 Pathogen - hypothetical protein TP0855 1 None None None 15639614 Common - exonuclease, putative TP0626 100 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 15639590 Common - phosphatidate cytidylyltransferase (cdsA) TP0602 204 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 15639226 Pathogen rpmG 50S ribosomal protein L33 TP0234 1 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 15639414 Common - hypothetical protein TP0423 11 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 15639132 Pathogen - hypothetical protein TP0138 1 None None None 15639585 Pathogen - hypothetical protein TP0597 1 None None None 15640031 Common - hypothetical protein TP0949a 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 15639328 Common ksgA dimethyladenosine transferase TP0337 244 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 15639179 Common - oxygen-independent coproporphyrinogen III oxidase, putative TP0186 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15639244 Common - apolipoprotein N-acyltransferase, putative TP0252 155 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 15640030 Common - permease TP0451a 23 COG2252 COG2252, Permeases General function prediction only 15639763 Common - hypothetical protein TP0776 94 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 15639438 Pathogen - hypothetical protein TP0447 1 None None None 15639160 Common - cation-activated repressor protein (troR) TP0167 81 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 15639600 Common - hypothetical protein TP0612 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 15639279 Pathogen - hypothetical protein TP0287 2 None None None 15639548 Common - hypothetical protein TP0559 93 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 15639885 Pathogen - hypothetical protein TP0900 1 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 15639891 Common - hypothetical protein TP0906 28 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 15639657 Common - D-alanine--D-alanine ligase (ddlA) TP0670 211 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 15639331 Common - folylpolyglutamate synthetase (folC) TP0340 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 15639153 Common - prolyl-tRNA synthetase TP0160 238 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639606 Pathogen - hypothetical protein TP0618 1 None None None 15639220 Common - biotin synthase, putative TP0228 110 COG1268 BioY, Uncharacterized conserved protein General function prediction only 15639064 Pathogen - hypothetical protein TP0070 1 None None None 15639869 Common - hypothetical protein TP0884 3 COG0795 COG0795, Predicted permeases General function prediction only 15639418 Common - V-type ATP synthase subunit B TP0427 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 15639751 Common - hypothetical protein TP0764 108 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15639818 Common - hypothetical protein TP0832 12 COG5401 COG5401, Spore germination protein General function prediction only 15639538 Common - ATPase (clpC) TP0549 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15639845 Pathogen - hypothetical protein TP0859 1 None None None 15639733 Common - pyruvate phosphate dikinase TP0746 232 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15639297 Common - CTP synthetase TP0305 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 15639759 Pathogen - hypothetical protein TP0772 1 None None None 15639881 Pathogen - hypothetical protein TP0896 1 None None None 15639914 Pathogen - hypothetical protein TP0929 1 None None None 15639313 Common - ribose/galactose ABC transporter, permease protein (rbsC-1) TP0322 122 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 15639558 Common - aminopeptidase P TP0569 150 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15639185 Common rplB 50S ribosomal protein L2 TP0192 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 15639012 Pathogen - transcription elongation factor TP0018 5 COG1747 COG1747, Uncharacterized N-terminal domain of the transcription elongation factor GreA Function unknown 15639513 Common - UDP-N-glucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (murG) TP0523 206 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15639360 Pathogen - hypothetical protein TP0369 1 COG4105 ComL, DNA uptake lipoprotein General function prediction only 15639498 Common - ATP-dependent Clp protease proteolytic component (clpP-1) TP0507 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15640014 Pathogen - hypothetical protein TP1030 1 None None None 15639329 Pathogen - hypothetical protein TP0338 1 None None None 15639835 Common rpmI 50S ribosomal protein L35 TP0849 7 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 15640016 Common - hypothetical protein TP1032 6 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 15639320 Common - serine hydroxymethyltransferase TP0329 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 15639165 Pathogen - hypothetical protein TP0172 1 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 15639893 Common trmD tRNA (guanine-N(1)-)-methyltransferase TP0908 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 15639725 Common - hypothetical protein TP0738 69 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 15639272 Pathogen - hypothetical protein TP0280 1 None None None 15639196 Common rpsH 30S ribosomal protein S8 TP0203 246 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 15639492 Common - rod shape-determining protein (rodA) TP0501 205 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15639688 Pathogen - DNA-directed RNA polymerase, putative TP0701 1 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 15639572 Pathogen - hypothetical protein TP0584 1 None None None 15639007 Common - hypothetical protein TP0013 6 None None None 15639201 Common secY preprotein translocase subunit SecY TP0208 225 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 15639742 Common - PTS system, nitrogen regulatory IIA component (ptsN-2) TP0755 104 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15639252 Pathogen - hypothetical protein TP0260 1 None None None 15639697 Common - hypothetical protein TP0710 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 15639830 Common - glyceraldehyde 3-phosphate dehydrogenase (gap) TP0844 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15639426 Pathogen - lipoprotein, 17 kDa (tpp17) TP0435 3 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 15639465 Common - hypothetical protein TP0474 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 15639306 Pathogen - hypothetical protein TP0314 1 None None None 15639246 Common rho transcription termination factor Rho TP0254 203 COG1158 Rho, Transcription termination factor Transcription 15639945 Common - flagellar basal-body rod protein (flgG-2) TP0961 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15639264 Common - SpoOJ regulator (soj) TP0272 231 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15639671 Common - methylgalactoside ABC transporter, periplasmic galactose-binding protein (mglB-2) TP0684 37 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15639787 Common - serine-type D-Ala-D-Ala carboxypeptidase (dacC) TP0800 149 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 15639625 Pathogen - hypothetical protein TP0638 1 None None None 15639118 Common - translation-associated GTPase TP0124 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 15639395 Pathogen - hypothetical protein TP0404 1 None None None 15639022 Common - hemolysin, putative TP0028 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15639617 Pathogen - hypothetical protein TP0629 1 None None None 15639219 Common - cobalt ABC transporter, ATP-binding protein TP0227 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15639772 Pathogen - hypothetical protein TP0785 2 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 15639623 Pathogen - hypothetical protein TP0636 1 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15639576 Common - hypothetical protein TP0588 9 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 15639749 Pathogen - hypothetical protein TP0762 1 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15639961 Common - hypothetical protein TP0977 101 COG0327 COG0327, Uncharacterized conserved protein Function unknown 15639353 Common - ribosomal protein L28 (rpmB) TP0362 31 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 15639077 Common - hypothetical protein TP0083 19 COG1306 COG1306, Uncharacterized conserved protein Function unknown 15639958 Pathogen - hypothetical protein TP0974 1 None None None 15639479 Common - methyl-accepting chemotaxis protein (mcp2-1) TP0488 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15639609 Pathogen - tpr protein J (tprJ) TP0621 1 None None None 15639127 Pathogen - hypothetical protein TP0133 1 None None None 15639901 Pathogen - hypothetical protein TP0916 1 None None None 15639923 Pathogen - hypothetical protein TP0938 1 None None None 15639445 Pathogen - hypothetical protein TP0454 1 COG3947 COG3947, Response regulator containing CheY-like receiver and SARP domains Signal transduction mechanisms 15639049 Pathogen - hypothetical protein TP0055 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 15639397 Common - glutamate racemase (murI) TP0406 183 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 15639852 Pathogen - hypothetical protein TP0867 1 None None None 15639862 Common - hypothetical protein TP0877 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15639665 Pathogen - hypothetical protein TP0678 1 None None None 15639972 Common - hypothetical protein TP0988 148 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 15639374 Common - hypothetical protein TP0383 129 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 15639389 Common fliE flagellar hook-basal body protein FliE TP0398 6 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 15639388 Common flgC flagellar basal body rod protein FlgC TP0397 122 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 15639409 Common - galactokinase TP0418 82 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 15639327 Common - comE protein, putative TP0336 105 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 15639655 Common - hypothetical protein TP0668 7 None None None 15639597 Common asnC asparaginyl-tRNA synthetase TP0609 182 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15639561 Common - hypothetical protein TP0572 10 COG2717 COG2717, Predicted membrane protein Function unknown 15639795 Common - acyl carrier protein (acpP) TP0808 185 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15639115 Common - hypothetical protein TP0121 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 15639859 Pathogen - hypothetical protein TP0874 2 None None None 15639262 Common - polynucleotide adenylyltransferase (pcnA) TP0270 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15639983 Common - cell division protein, putative TP0999 201 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15639628 Common hisS histidyl-tRNA synthetase TP0641 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15640003 Pathogen - glu-tRNA amidotransferase, subunit C (gatC) TP1019 1 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 15639521 Common - V-type ATPase, subunit F, putative TP0531 2 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 15639878 Common - hypothetical protein TP0893 3 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 15639637 Common - hypothetical protein TP0650 185 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 15639311 Pathogen - hypothetical protein TP0320 1 None None None 15639946 Common - hypothetical protein TP0962 187 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 15639216 Pathogen - hypothetical protein TP0224 1 None None None 15639977 Common - rare lipoprotein A, putative TP0993 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 15639054 Common rplI 50S ribosomal protein L9 TP0060 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 15639143 Pathogen - hypothetical protein TP0150 1 None None None 15639644 Common - carbon storage regulator (csrA) TP0657 84 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 15639823 Common - threonyl-tRNA synthetase (thrS) TP0837 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639871 Common - polynucleotide phosphorylase/polyadenylase TP0886 236 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 15639106 Common - aminopeptidase C (pepC) TP0112 15 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 15639284 Common - outer membrane protein (tpn50) TP0292 139 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15639280 Common - spore coat polysaccharide biosynthesis protein (spsF) TP0288 27 COG1861 SpsF, Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog Cell envelope biogenesis, outer membrane 15639939 Pathogen - hypothetical protein TP0955 1 None None None 15640023 Common - adenine phosphoribosyltransferase TP1039 167 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15639416 Pathogen - hypothetical protein TP0425 1 None None None 15639222 Common - primosomal protein N (priA) TP0230 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 15639753 Pathogen - hypothetical protein TP0766 1 None None None 15639611 Common - membrane-bound lytic murein transglycosylase D (dniR) TP0623 94 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 15639727 Common - hypothetical protein TP0740 40 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 15639062 Common - hypothetical protein TP0068 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 15639231 Common rplJ 50S ribosomal protein L10 TP0239 203 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 15639433 Common - DNA repair protein (recN) TP0442 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 15639240 Pathogen - hypothetical protein TP0248 1 None None None 15639708 Common fliM flagellar motor switch protein FliM TP0721 107 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 15639183 Common rplD 50S ribosomal protein L4 TP0190 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 15639797 Common - DNA adenine methyltransferase (dam) TP0810 97 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 15639447 Pathogen - hypothetical protein TP0456 1 None None None 15639860 Common - hypothetical protein TP0875 206 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 15639582 Common - hypothetical protein TP0594 15 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 15639813 Common - hypothetical protein TP0827 9 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 15639238 Common - hypothetical protein TP0246 3 None None None 15639190 Pathogen - ribosomal protein L29 (rpmC) TP0197 1 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 15639095 Common - cytochrome c biogenesis protein (ccdA) TP0101 132 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 15639678 Common - hypothetical protein TP0691 138 COG1354 COG1354, Uncharacterized conserved protein Function unknown 15639593 Common tsf elongation factor Ts TP0605 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 15639843 Pathogen - hypothetical protein TP0857 1 None None None 15639953 Pathogen - hypothetical protein TP0969 1 None None None 15639549 Common - transketolase A (tktA) TP0560 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15639503 Common - hypothetical protein TP0512 193 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 15639014 Pathogen - 76K protein TP0020 1 None None None 15639917 Pathogen - hypothetical protein TP0932 1 None None None 15639589 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase TP0601 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 15639428 Pathogen - hypothetical protein TP0437 1 None None None 15639695 Pathogen - hypothetical protein TP0708 1 None None None 15639250 Pathogen - hypothetical protein TP0258 3 None None None 15638998 Common - recF protein (recF) TP0003 152 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 15639467 Common - acetate kinase (ack) TP0476 162 COG0282 ackA, Acetate kinase Energy production and conversion 15639275 Common - lipopolysaccharide core biosynthesis protein (kdtB) TP0283 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 15639556 Pathogen - hypothetical protein TP0567 3 COG3334 COG3334, Uncharacterized conserved protein Function unknown 15639781 Common - S-adenosylmethionine synthetase TP0794 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 15639266 Common - deoxycytidylate deaminase, putative TP0274 83 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 15639460 Common - hypothetical protein TP0469 18 COG0457 NrfG, FOG: TPR repeat General function prediction only 15639638 Common - hypothetical protein TP0651 56 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 15639542 Common - hypothetical protein TP0553 127 COG0628 PerM, Predicted permease General function prediction only 15639744 Common - polypeptide deformylase (def) TP0757 210 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 15639968 Common - heat shock protein 90 TP0984 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 15639024 Common groEL chaperonin GroEL TP0030 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15639282 Common - hypothetical protein TP0290 130 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15639627 Common - methyl-accepting chemotaxis protein (mcp2-3) TP0640 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15639344 Common - ribonuclease H (rnhA) TP0353 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 15639138 Common - thiamine ABC transporter, thiamine-binding periplasmic protein, putative TP0144 66 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 15639318 Pathogen - cationic outer membrane protein (ompH) TP0327 2 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 15639714 Common flgE flagellar hook protein FlgE TP0727 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 15639163 Common - pfs protein (pfs) TP0170 90 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15639487 Pathogen - hypothetical protein TP0496 2 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15639800 Common - thioredoxin reductase (trxB) TP0814 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15639995 Common - peptidyl-tRNA hydrolase TP1011 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 15639197 Common rplF 50S ribosomal protein L6 TP0204 219 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 15640018 Common - hypothetical protein TP1034 100 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 15639630 Common - DNA polymerase III, subunit epsilon (dnaQ) TP0643 199 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15639494 Pathogen - hypothetical protein TP0503 1 None None None 15639998 Pathogen - hypothetical protein TP1014 1 None None None 15639005 Pathogen - tpr protein B (tprB) TP0011 1 None None None 15639700 Common - flagellar-associated GTP-binding protein (flhF) TP0713 243 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 15639096 Common - rep helicase, single-stranded DNA-dependent ATPase (rep) TP0102 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15639574 Common leuS leucyl-tRNA synthetase TP0586 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639604 Common - ribose 5-phosphate isomerase (rpiA) TP0616 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 15639802 Pathogen - hypothetical protein TP0816 1 None None None 15639970 Common - hypothetical protein TP0986 50 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15639035 Pathogen - hypothetical protein TP0041 1 None None None 15639225 Common - anti-sigma F factor antagonist, putative TP0233 48 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 15639864 Common - hypothetical protein TP0879 7 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 15639376 Pathogen - hypothetical protein TP0385 1 None None None 15639382 Common - integrase/recombinase (codV) TP0391 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15639470 Pathogen - hypothetical protein TP0479 1 None None None 15639290 Common - exported protein (tpn38b) TP0298 80 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 15639632 Pathogen - hypothetical protein TP0645 1 None None None 15639027 Common - hypothetical protein TP0033 16 COG4330 COG4330, Predicted membrane protein Function unknown 15639308 Pathogen - tpr protein G (tprG) TP0317 1 None None None 15639774 Pathogen - hypothetical protein TP0787 1 None None None 15639595 Pathogen - hypothetical protein TP0607 1 None None None 15639943 Pathogen - hypothetical protein TP0959 1 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 15639563 Pathogen - carboxypeptidase, 47 kDa TP0574 1 None None None 15639324 Common - hypothetical protein TP0333 5 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 15639588 Common - zinc protease, putative TP0600 199 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15639766 Common - dedA protein (dedA) TP0779 27 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15639489 Common - rod shape-determining protein (mreC) TP0498 139 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 15639121 Pathogen - hypothetical protein TP0127 1 None None None 15639237 Common - hypothetical protein TP0245 3 COG0714 COG0714, MoxR-like ATPases General function prediction only 15639000 Common - DNA gyrase, subunit A (gyrA) TP0005 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15639080 Pathogen - hypothetical protein TP0086 2 None None None 15639619 Common - protein-glutamate methylesterase (cheB) TP0631 220 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 15639908 Pathogen - hypothetical protein TP0923 1 None None None 15639299 Common - hypothetical protein TP0307 9 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 15639355 Common - purine-binding chemotaxis protein (cheW-1) TP0364 135 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 15639532 Common - Holliday junction DNA helicase (ruvA) TP0543 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 15639876 Common infB translation initiation factor IF-2 TP0891 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 15639905 Common - hypothetical protein TP0920 5 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15639736 Pathogen - hypothetical protein TP0749 1 None None None 15639113 Common - amino acid ABC transporter, permease protein (yaeE) TP0119 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 15639895 Pathogen - hypothetical protein TP0910 1 None None None 15639047 Common nrdF ribonucleotide-diphosphate reductase subunit beta TP0053 159 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 15639089 Common - hypothetical protein TP0095 10 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 15639991 Common thyX FAD-dependent thymidylate synthase TP1007 42 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 15639129 Pathogen - hypothetical protein TP0135 1 None None None 15639451 Common - hypothetical protein TP0460 72 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15639440 Pathogen - hypothetical protein TP0449 1 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15639825 Pathogen - hypothetical protein TP0839 1 None None None 15639347 Common - RNA-binding protein, putative TP0356 65 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 15639523 Pathogen - hypothetical protein TP0534 1 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 15639663 Pathogen - hypothetical protein TP0676 1 None None None 15639646 Common - flagellar hook-associated protein FlgL TP0659 86 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15639052 Common - replicative DNA helicase (dnaB) TP0058 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15639477 Pathogen - antigen, p83/100 TP0486 3 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 15639302 Pathogen - hypothetical protein TP0310 1 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15639925 Pathogen - hypothetical protein TP0940 1 None None None 15639402 Common secF preprotein translocase subunit SecF TP0411 200 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 15639955 Common - membrane antigen, pathogen-specific (tpd) TP0971 25 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 15639411 Pathogen - hypothetical protein TP0420 1 None None None 15639058 Pathogen - hypothetical protein TP0064 1 None None None 15639286 Common - phosphoribosylpyrophosphate synthetase TP0294 237 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15639857 Common fliD flagellar hook-associated protein FliD TP0872 77 COG1345 FliD, Flagellar capping protein Cell motility and secretion 15639260 Common - hypothetical protein TP0268 34 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 15639989 Common - DNA polymerase III subunits gamma and tau TP1005 242 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15639837 Pathogen - hypothetical protein TP0851 4 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 15639613 Pathogen - hypothetical protein TP0625 1 None None None 15639039 Common - adenosine deaminase TP0045 89 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 15639930 Common - ribulose-phosphate 3-epimerase (cfxE) TP0945 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 15639337 Pathogen - hypothetical protein TP0346 1 None None None 15639361 Pathogen - hypothetical protein TP0370 1 None None None 15639210 Common - sigma factor SigB regulation protein, putative TP0218 72 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 15639996 Common - RNA polymerase sigma-43 factor (sigA) TP1012 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15639276 Pathogen - hypothetical protein TP0284 1 None None None 15639026 Common - hypothetical protein TP0032 25 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 15639431 Common - spore coat polysaccharide biosynthesis protein, putative TP0440 55 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15639799 Pathogen - hypothetical protein TP0813 1 None None None 15639684 Pathogen - hypothetical protein TP0697 1 None None None 15639932 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-binding (cyp) TP0947 190 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 15639325 Common - hypothetical protein TP0334 59 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 15639791 Common - sugar ABC transporter, ATP-binding protein (ugpC) TP0804 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 15639693 Common - hypothetical protein TP0706 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15639422 Common - hypothetical protein TP0431 116 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 15639935 Pathogen rpmH 50S ribosomal protein L34 TP0951 2 None None None 15639098 Common - 5'-nucleotidase (ushA) TP0104 136 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 15639497 Common tig trigger factor TP0506 203 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 15639676 Common engA GTP-binding protein EngA TP0689 229 COG1160 COG1160, Predicted GTPases General function prediction only 15639175 Common - hypothetical protein TP0182 40 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 15639004 Pathogen - hypothetical protein TP0010 1 None None None 15639037 Common - soluble lytic transglycosylase, putative TP0043 160 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15639667 Common - O-sialoglycoprotein endopeptidase TP0680 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 15639468 Common - glucose-6-phosphate 1-dehydrogenase, putative TP0477 119 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 15639256 Common - deoxyribose-phosphate aldolase (deoC) TP0264 134 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 15639350 Pathogen - hypothetical protein TP0359 1 COG3330 COG3330, Uncharacterized protein conserved in bacteria Function unknown 15639390 Common fliF flagellar MS-ring protein TP0399 121 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 15639415 Pathogen - V-type ATP synthase subunit E TP0424 2 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 15639919 Common - glutamate transporter, putative TP0934 38 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 15639658 Pathogen - sn-1,2-diacylglycerol cholinephosphotransferase, putative TP0671 1 COG5050 EPT1, sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases Lipid metabolism 15639316 Pathogen - hypothetical protein TP0325 2 None None None 15639653 Pathogen - hypothetical protein TP0666 1 None None None 15639564 Common - peptide chain release factor 2 (prfB) TP0576 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 15639102 Common - diphosphate--fructose-6-phosphate 1-phosphotransferase TP0108 150 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 15639140 Common - alpha-amylase 1, putative TP0147 11 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 15639775 Pathogen - hypothetical protein TP0788 1 None None None 15639461 Common - hypothetical protein TP0470 14 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 15639620 Common - tryptophanyl-tRNA synthetase TP0632 249 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639061 Common - hypothetical protein TP0067 100 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15639399 Common - hypothetical protein TP0408 169 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15639268 Common - hypothetical protein TP0276 76 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 15639729 Common obgE GTPase ObgE TP0742 245 COG0536 Obg, Predicted GTPase General function prediction only 15639539 Common trmE tRNA modification GTPase TrmE TP0550 218 COG0486 ThdF, Predicted GTPase General function prediction only 15639249 Common glpQ glycerophosphodiester phosphodiesterase TP0257 69 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 15639508 Common - Holliday junction nuclease (ruvC) TP0517 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 15639706 Pathogen - hypothetical protein TP0719 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 15639633 Pathogen - hypothetical protein TP0646 2 None None None 15639084 Common - UDP-N-acetylmuramate dehydrogenase (murB) TP0090 144 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 15639966 Common - glpG protein, putative TP0982 95 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 15639910 Common - flavodoxin TP0925 6 COG0716 FldA, Flavodoxins Energy production and conversion 15639959 Common - hypothetical protein TP0975 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 15639716 Pathogen - treponemal aqueous protein (tap1) TP0729 2 None None None 15639681 Common - 5,10-methenyltetrahydrofolate synthetase, putative TP0694 47 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 15639133 Common - hypothetical protein TP0139 104 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15639152 Pathogen - hypothetical protein TP0159 1 None None None 15639811 Pathogen - hypothetical protein TP0825 1 None None None 15639836 Common infC translation initiation factor IF-3 TP0850 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 15639856 Pathogen - hypothetical protein TP0871 1 None None None 15639814 Common - holo-acyl-carrier protein synthase (acpS) TP0828 118 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 15639176 Pathogen - hypothetical protein TP0183 1 None None None 15639578 Pathogen - ribosomal protein L36 (rpmJ-2) TP0590 1 None None None 15639293 Common - hypothetical protein TP0301 108 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 15639872 Common rpsO 30S ribosomal protein S15 TP0887 204 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 15639448 Pathogen - hypothetical protein TP0457 2 None None None 15639554 Common - hypothetical protein TP0565 19 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 15639721 Common - purine nucleoside phosphorylase (deoD) TP0734 91 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 15639755 Pathogen - membrane protein (tmpA) TP0768 1 None None None 15639234 Common - DNA-directed RNA polymerase subunit beta' TP0242 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15639865 Common - membrane spanning protein, putative TP0880 34 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 15639157 Common - ABC transporter, ATP-binding protein (troB) TP0164 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 15639848 Common - peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) TP0862 127 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 15639242 Pathogen - hypothetical protein TP0250 1 None None None 15639068 Common - sugar ABC transporter, periplasmic binding protein (y4oP) TP0074 63 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15639435 Common - hypothetical protein TP0444 105 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15638996 Common - chromosomal replication initiator protein (dnaA) TP0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15639739 Pathogen - hypothetical protein TP0752 1 None None None 15639874 Common - tRNA pseudouridine 55 synthase (truB) TP0889 242 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 15639838 Common - prolipoprotein diacylglyceryl transferase TP0852 189 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 15639783 Common - hypothetical protein TP0796 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 15639406 Pathogen - hypothetical protein TP0415 1 None None None 15639131 Pathogen - hypothetical protein TP0137 1 None None None 15640026 Common dnaJ heat shock protein TP0217 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15640007 Common recX recombination regulator RecX TP1023 15 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 15639363 Common - 50S ribosomal protein L25/general stress protein Ctc TP0372 168 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 15639345 Common - thymidylate kinase (tmk) TP0354 226 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 15639982 Common - sodium/proton-dependent alanine transporter TP0998 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 15639075 Common - hypothetical protein TP0081 34 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 15639987 Pathogen - hypothetical protein TP1003 1 None None None 15639227 Pathogen secE preprotein translocase subunit SecE TP0235 1 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 15639087 Pathogen - hypothetical protein TP0093 1 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 15640000 Common - basic membrane protein (tpn39b) TP1016 10 None None None 15639517 Common - V-type ATPase, subunit D (atpD-2) TP0527 39 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 15639475 Common - hypothetical protein TP0484 4 None None None 15639927 Pathogen - hypothetical protein TP0942 1 None None None 15639827 Common - periplasmic serine protease DO (htrA-2) TP0841 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15639641 Common - spermidine/putrescine ABC transporter, permease protein (potC) TP0654 205 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 15639711 Common motB flagellar motor protein MotB TP0724 131 COG1360 MotB, Flagellar motor protein Cell motility and secretion 15639746 Pathogen - hypothetical protein TP0759 1 None None None 15639738 Pathogen - hypothetical protein TP0751 1 None None None 15639452 Pathogen - hypothetical protein TP0461 2 None None None 15639456 Pathogen - hypothetical protein TP0465 1 None None None 15639525 Pathogen secG preprotein translocase subunit SecG TP0536 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 15639289 Common - hypothetical protein TP0297 3 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 15639040 Common - hypothetical protein TP0046 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 15639768 Pathogen - hypothetical protein TP0781 1 None None None 15639762 Common - endonuclease III (nth) TP0775 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 15639050 Common - pyruvate carboxylase subunit B TP0056 181 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 15639357 Common - chemotaxis response regulator (cheY) TP0366 219 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 15639384 Common - smf protein (smf) TP0393 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 15639906 Common - NADH oxidase TP0921 240 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 15639504 Common trkA potassium transporter peripheral membrane component TP0513 132 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15639888 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD) TP0903 150 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15639483 Common - DNA primase (dnaG) TP0492 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15639662 Pathogen - hypothetical protein TP0675 1 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 15639807 Common - lipoprotein (tpn32) TP0821 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 15639283 Common - hypothetical protein TP0291 68 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 15639092 Common - heat-shock protein, putative TP0098 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15639198 Common rplR 50S ribosomal protein L18 TP0205 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 15639941 Common - Tp33 protein TP0957 16 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 15639206 Common rplQ 50S ribosomal protein L17 TP0213 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 15639583 Common - adenylate kinase (adk) TP0595 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 15639385 Common - DNA topoisomerase I (topA) TP0394 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15639534 Common - methylgalactoside ABC transporter, periplasmic galactose-binding protein (mglB-1) TP0545 80 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 15639648 Pathogen - hypothetical protein TP0661 1 None None None 15639335 Common - transcription-repair coupling factor (trcF) TP0344 215 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 15639669 Common - cell division protein (ftsJ) TP0682 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 15639976 Pathogen - hypothetical protein TP0992 2 None None None 15639897 Common - hypothetical protein TP0912 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 15639486 Pathogen - hypothetical protein TP0495 1 None None None 15639028 Common - ABC transporter, periplasmic binding protein TP0034 161 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15640011 Common - uridine phosphorylase (udp) TP1027 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 15639123 Pathogen - hypothetical protein TP0129 1 None None None 15639404 Common - phosphoglucomutase TP0413 96 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15639169 Pathogen - hypothetical protein TP0176 1 None None None 15639173 Pathogen - hypothetical protein TP0180 1 None None None 15639378 Common - cell division protein (ftsW) TP0387 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15639042 Common - hypothetical protein TP0048 4 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 15639107 Common - Lambda CII stability-governing protein (hflK) TP0113 138 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15639510 Common - response regulatory protein (atoC) TP0519 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15639191 Common rpsQ 30S ribosomal protein S17 TP0198 229 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 15639608 Pathogen - tpr protein I (tprI) TP0620 1 None None None 15639119 Common - exodeoxyribonuclease (exoA) TP0125 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15639777 Common - antibiotic transport protein, putative TP0790 106 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 15639699 Common - ATP-binding protein (ylxH-1) TP0712 143 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15639142 Pathogen - hypothetical protein TP0149 1 None None None 15639463 Common - excinuclease ABC, subunit C (uvrC) TP0472 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15639270 Pathogen - hypothetical protein TP0278 1 None None None 15639964 Common - histidine phosphokinase/phophatase (ntrB) TP0980 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15639867 Common - hypothetical protein TP0882 3 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15639565 Pathogen - hypothetical protein TP0577 1 None None None 15639833 Pathogen - hypothetical protein TP0847 1 None None None 15639254 Common - catabolite gene activator (crp) TP0262 118 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15639162 Pathogen - hypothetical protein TP0169 1 None None None 15639506 Pathogen - hypothetical protein TP0515 2 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 15639424 Pathogen - hypothetical protein TP0433 1 None None None 15639167 Pathogen - hypothetical protein TP0174 1 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15639957 Common pheS phenylalanyl-tRNA synthetase subunit alpha TP0973 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 15639481 Pathogen - hypothetical protein TP0490 1 None None None 15639009 Common pheT phenylalanyl-tRNA synthetase subunit beta TP0015 158 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 15639366 Pathogen - hypothetical protein TP0375 1 None None None 15639793 Common - femA protein, putative TP0806 26 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 15639392 Common fliH flagellar assembly protein H TP0401 69 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15640005 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B TP1021 211 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 15639952 Pathogen - hypothetical protein TP0968 1 None None None 15639691 Common - single-stranded-DNA-specific exonuclease (recJ) TP0704 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15639994 Common - nucleoside-diphosphate kinase (ndk) TP1010 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 15639340 Common - peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) TP0349 129 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 15639349 Common - hypothetical protein TP0358 34 COG1543 COG1543, Uncharacterized conserved protein Function unknown 15639723 Common - ferredoxin--NADP(+) reductase subunit alpha TP0736 83 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 15639002 Common - hypothetical protein TP0007 6 None None None 15639031 Common - D-specific D-2-hydroxyacid dehydrogenase TP0037 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15639490 Common - rod shape-determining protein (mreD) TP0499 6 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 15639710 Pathogen - hypothetical protein TP0723 1 None None None 15639686 Pathogen - hypothetical protein TP0699 1 None None None 15639203 Common rpsM 30S ribosomal protein S13 TP0210 228 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 15639913 Pathogen - hypothetical protein TP0928 1 None None None 15639846 Pathogen - hypothetical protein TP0860 1 None None None 15639757 Common - ATP-dependent RNA helicase TP0770 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15639194 Common rplE 50S ribosomal protein L5 TP0201 248 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 15639938 Common - hypothetical protein TP0954 100 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 15639314 Common - ribose/galactose ABC transporter, permease protein (rbsC-2) TP0323 130 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 15639920 Common - N-acetylphosphinothricin-tripetide-deacetylase, putative TP0935 106 COG0657 Aes, Esterase/lipase Lipid metabolism 15639019 Common - hypothetical protein TP0025 35 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 15639437 Common - gcpE protein (gcpE) TP0446 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 15639033 Pathogen - hypothetical protein TP0039 1 None None None 15639066 Common - hypothetical protein TP0072 8 COG4545 COG4545, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 15639413 Pathogen - hypothetical protein TP0422 1 None None None 15639879 Common - hypothetical protein TP0894 64 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15639150 Pathogen - hypothetical protein TP0157 3 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15639323 Pathogen - hypothetical protein TP0332 1 None None None 15639178 Common - signal peptidase I (sip) TP0185 57 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15639586 Pathogen - hypothetical protein TP0598 1 None None None 15639010 Common - ATP-dependent protease LA (lon-1) TP0016 101 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 15639527 Common pgk phosphoglycerate kinase TP0538 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 15639615 Common - exonuclease (sbcC) TP0627 134 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 15639181 Common rpsJ 30S ribosomal protein S10 TP0188 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 15639622 Common - DNA ligase (lig) TP0634 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15639816 Common truA tRNA pseudouridine synthase A TP0830 230 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 15639840 Common - hypothetical protein TP0854 61 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 15639651 Pathogen - flagellar filament outer layer protein (flaA-2) TP0664 2 None None None 15639883 Common - ATP-dependent nuclease, subunit A, putative TP0898 199 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 15639552 Pathogen - hypothetical protein TP0563 2 None None None 15639473 Pathogen - hypothetical protein TP0482 1 None None None 15639245 Common - hypothetical protein TP0253 26 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 15639643 Pathogen - hypothetical protein TP0656 1 None None None 15639786 Pathogen - hypothetical protein TP0799 1 None None None 15639454 Pathogen - hypothetical protein TP0463 1 None None None 15639312 Common - ribose/galactose ABC transporter, ATP-binding protein (rbsA-2) TP0321 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 15639656 Common dnaE DNA polymerase III subunit alpha TP0669 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 15639933 Common - spoIIIJ-associated protein (jag) TP0948 62 COG1847 Jag, Predicted RNA-binding protein General function prediction only 15639986 Common - hypothetical protein TP1002 5 COG5497 COG5497, Predicted secreted protein Function unknown 15639104 Pathogen - hypothetical protein TP0110 1 None None None 15639458 Pathogen - hypothetical protein TP0467 1 None None None 15639748 Common - hypothetical protein TP0761 3 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15639929 Pathogen - hypothetical protein TP0944 2 None None None 15639057 Pathogen rpsF 30S ribosomal protein S6 TP0063 2 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 15639511 Common - DNA polymerase III, gamma and tau subunits, putative TP0521 127 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15639820 Common - tyrosyl-tRNA synthetase (tyrS) TP0834 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 161579586 Common - elongation factor Tu TP0187 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15639502 Common - transcription factor (carD) TP0511 63 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 15639171 Pathogen - hypothetical protein TP0178 1 None None None 15639145 Common - nitrogen fixation protein (rnfC) TP0152 68 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 15640021 Common - hemolysin III (hlyIII) TP1037 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 15640028 Common rpmD 50S ribosomal protein L30 TP0206a 116 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 15639301 Common - amino acid ABC transporter, periplasmic binding protein TP0309 68 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15639635 Common - hypothetical protein TP0648 94 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15639073 Common - hypothetical protein TP0079 61 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 15639936 Common - lipase, putative TP0952 10 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 15639420 Common - V-type ATP synthase subunit I TP0429 20 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 15639948 Common - ABC transporter, ATP-binding protein TP0964 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15640013 Common - hypothetical protein TP1029 3 None None None 15639769 Pathogen - hypothetical protein TP0782 1 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15639343 Common - hypothetical protein TP0352 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 15639070 Common - sugar ABC transporter, permease protein (y4oR) TP0076 140 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 15639352 Common - lysophosphatidic acid acyltransferase, putative TP0361 57 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15639899 Pathogen - hypothetical protein TP0914 2 None None None 15639155 Common ruvB Holliday junction DNA helicase B TP0162 213 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 15639443 Common ileS isoleucyl-tRNA synthetase TP0452 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15639214 Pathogen - hypothetical protein TP0222 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15639148 Common - hypothetical protein TP0155 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15639013 Common - transcription elongation factor (greA) TP0019 203 COG0782 GreA, Transcription elongation factor Transcription 15639332 Common murC UDP-N-acetylmuramate--L-alanine ligase TP0341 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 15639809 Common - desulfoferrodoxin (rbo) TP0823 20 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 15639560 Common - Tp70 protein TP0571 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 15639253 Common - catabolite gene activator, putative TP0261 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 15639295 Common - DNA mismatch repair protein (mutL) TP0303 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 15639591 Common - hypothetical protein TP0603 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15639974 Common - hypothetical protein TP0990 6 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 15639109 Common - phosphomethypyrimidine kinase (thiD) TP0115 216 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 15639546 Common - hypothetical protein TP0557 10 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 15639704 Common - flagellar biosynthetic protein (fliQ) TP0717 129 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 15639204 Common - 30S ribosomal protein S11 TP0211 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 15639980 Common - hypothetical protein TP0996 7 None None None 15639082 Pathogen - hypothetical protein TP0088 1 None None None 15639079 Common - PTS system, nitrogen regulatory IIA component (ptsN-1) TP0085 125 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 15639660 Common gltX glutamyl-tRNA synthetase TP0673 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15639090 Common - dnaK suppressor, putative TP0096 122 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 15639408 Common lnt apolipoprotein N-acyltransferase TP0417 160 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 15639117 Pathogen - hypothetical protein TP0123 1 None None None 15639394 Pathogen - flagellar protein, putative TP0403 1 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15639670 Common - octaprenyl-diphosphate synthase TP0683 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15639371 Common - DNA repair helicase, putative TP0380 62 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 15639120 Pathogen - hypothetical protein TP0126 1 None None None 15639233 Common rpoB DNA-directed RNA polymerase subunit beta TP0241 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 15639850 Common - hypothetical protein TP0864 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15639567 Pathogen - hypothetical protein TP0579 1 None None None 15639904 Common - thioredoxin (trx) TP0919 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15639674 Common - DNA recombinase (recG) TP0687 224 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 15639854 Pathogen - hypothetical protein TP0869 1 None None None 15639359 Pathogen - hypothetical protein TP0368 1 None None None