Methanothermobacter thermautotrophicus str. Delta H, complete genome NC_000916 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 15678504 Common - pyruvate dehydrogenase / acetolactate synthase MTH476 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15679025 Common - DNA topoisomerase VI subunit B MTH1007 34 COG1389 COG1389, DNA topoisomerase VI, subunit B DNA replication, recombination, and repair 15678086 Nonpathogen - hypothetical protein MTH57 1 None None None 15679440 Common ilvH acetolactate synthase 3 regulatory subunit MTH1443 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 15679144 Common - polyferredoxin (MvhB) MTH1133 178 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15679385 Common - 3-isopropylmalate dehydratase, LeuD subunit MTH1386 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 15679355 Nonpathogen - hypothetical protein MTH1356 10 COG1810 COG1810, Uncharacterized protein conserved in archaea Function unknown 15678992 Nonpathogen - hypothetical protein MTH974 3 COG1873 COG1873, Uncharacterized conserved protein Function unknown 15679738 Common - cytochrome C-type biogenesis protein MTH1746 18 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 15678466 Nonpathogen - hypothetical protein MTH438 1 None None None 15678715 Nonpathogen - ribonuclease P protein component 3 MTH688 19 COG1603 RPP1, RNase P/RNase MRP subunit p30 Translation, ribosomal structure and biogenesis 15679316 Nonpathogen - hypothetical protein MTH1316 35 COG1628 COG1628, Uncharacterized conserved protein Function unknown 15679511 Common - cobalt-precorrin-6Y C(5)-methyltransferase MTH1514 123 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 15678912 Common - ATP-dependent protease LA related protein MTH892 26 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 15679465 Nonpathogen - ferredoxin MTH1468 25 COG1146 COG1146, Ferredoxin Energy production and conversion 15678956 Common - iron repressor MTH936 112 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 15678390 Common - capsular polysaccharide biosynthesis protein MTH362 117 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15679714 Common - transcriptional regulator Icc related protein MTH1722 77 COG1409 Icc, Predicted phosphohydrolases General function prediction only 15678065 Common rps4p 30S ribosomal protein S4 MTH35 106 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15678863 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase MTH843 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 15679713 Common - unknown (contains ferredoxin domain) MTH1719 35 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 15678513 Nonpathogen - hypothetical protein MTH485 1 None None None 15678547 Nonpathogen - hypothetical protein MTH519 3 None None None 15678316 Nonpathogen - hypothetical protein MTH288 1 None None None 15678780 Common - heavy-metal transporting CPx-type ATPase MTH755 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15678699 Nonpathogen - hypothetical protein MTH672 8 COG4827 COG4827, Predicted transporter General function prediction only 15679557 Common - nitrogenase GlnBa subunit MTH1561 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15679396 Common - sirohydrochlorin cobaltochelatase MTH1397 55 COG2138 COG2138, Uncharacterized conserved protein Function unknown 15678813 Common - hypothetical protein MTH789 32 COG3503 COG3503, Predicted membrane protein Function unknown 15679899 Common - pyruvate carboxylase subunit A MTH1917 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 15679865 Nonpathogen - hypothetical protein MTH1877 24 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 15678447 Common - CTP synthetase MTH419 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 15679137 Nonpathogen - hypothetical protein MTH1126 6 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 15679520 Common - glucose-1-phosphate adenylyltransferase related protein MTH1523 206 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 15679333 Nonpathogen - hypothetical protein MTH1333 1 None None None 15679779 Common - glucose-1-phosphate thymidylyltransferase MTH1791 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15678777 Nonpathogen - hypothetical protein MTH752 8 COG4079 COG4079, Uncharacterized protein conserved in archaea Function unknown 15679723 Common - phosphate transport system ATP-binding MTH1731 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 15679633 Nonpathogen - hypothetical protein MTH1638 1 None None None 15678468 Common - sensory transduction regulatory protein MTH440 220 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 15679452 Common - threonyl-tRNA synthetase MTH1455 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678593 Nonpathogen - hypothetical protein MTH565 1 None None None 15678854 Common - hypothetical protein MTH834 24 COG1548 COG1548, Predicted transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 15679859 Common - nitrogenase iron-molybdenum cofactor biosynthesis protein NifB MTH1871 132 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 15679749 Nonpathogen - hypothetical protein MTH1761 7 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 15679379 Common glyA serine hydroxymethyltransferase MTH1380 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 15679104 Common - ABC transporter (ATP-binding MTH1093 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15679289 Common - hypothetical protein MTH1285 151 COG1733 COG1733, Predicted transcriptional regulators Transcription 15679035 Nonpathogen - GTP cyclohydrolase III MTH1017 15 COG2429 COG2429, Uncharacterized conserved protein Function unknown 15678307 Nonpathogen - hypothetical protein MTH279 1 None None None 15679002 Common - 1,3-propanediol dehydrogenase MTH984 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 15678727 Common - hypothetical protein MTH700 62 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 15679552 Nonpathogen - tungsten formylmethanofuran dehydrogenase, subunit D MTH1556 17 COG1153 FwdD, Formylmethanofuran dehydrogenase subunit D Energy production and conversion 15679765 Nonpathogen - hypothetical protein MTH1777 3 None None None 15679399 Nonpathogen - hypothetical protein MTH1400 2 None None None 15679788 Nonpathogen - hypothetical protein MTH1800 1 None None None 15678540 Nonpathogen - hypothetical protein MTH512 6 None None None 15679220 Nonpathogen - hypothetical protein MTH1209 1 COG4933 COG4933, Uncharacterized conserved protein Function unknown 15678582 Nonpathogen - hypothetical protein MTH554 25 COG2042 COG2042, Uncharacterized conserved protein Function unknown 15678959 Common - hypothetical protein MTH939 154 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 15678882 Nonpathogen - hypothetical protein MTH862 11 COG4090 COG4090, Uncharacterized protein conserved in archaea Function unknown 15678677 Nonpathogen - hypothetical protein MTH650 34 COG2016 COG2016, Predicted RNA-binding protein (contains PUA domain) Translation, ribosomal structure and biogenesis 15678689 Common - nitrogen regulatory protein P-II MTH662 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15679737 Common - protein disulphide isomerase MTH1745 93 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 15679641 Nonpathogen - hypothetical protein MTH1646 3 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15679114 Nonpathogen - hypothetical protein MTH1103 1 None None None 15679904 Nonpathogen - DNA-directed RNA polymerase subunit RPC10 MTH680a 2 COG1996 RPC10, DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) Transcription 15679656 Common - anthranilate phosphoribosyltransferase MTH1661 218 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 15678929 Nonpathogen - hypothetical protein MTH909 9 COG1818 COG1818, Predicted RNA-binding protein, contains THUMP domain General function prediction only 15679205 Common - acetylpolyamine aminohydolase MTH1194 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 15678413 Nonpathogen - hypothetical protein MTH385 8 COG4041 COG4041, Predicted membrane protein Function unknown 15678562 Nonpathogen - hypothetical protein MTH534 1 None None None 15678300 Common - acetyl / acyl transferase related protein MTH272 91 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 15679299 Common - coenzyme F420-reducing hydrogenase subunit beta MTH1297 38 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 15679572 Nonpathogen - hypothetical protein MTH1577 13 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 15679070 Common - elongation factor EF-2 MTH1057 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15678628 Nonpathogen - hypothetical protein MTH600 15 COG2034 COG2034, Predicted membrane protein Function unknown 15678479 Common - magnesium chelatase subunit ChlI MTH451 80 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 15678674 Nonpathogen - hypothetical protein MTH647 6 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 15678233 Common - hydrogenase expression/formation protein HypE MTH205 178 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15679750 Common - DNA mismatch recognition protein MutS MTH1762 93 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15678050 Common rpl6p 50S ribosomal protein L6P MTH19 127 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 15679015 Common - carbamoyl-phosphate synthase, large subunit MTH997 230 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15678682 Nonpathogen - hypothetical protein MTH655 8 COG1822 COG1822, Predicted archaeal membrane protein Function unknown 15679174 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit E MTH1163 14 COG4059 MtrE, Tetrahydromethanopterin S-methyltransferase, subunit E Coenzyme metabolism 15679850 Nonpathogen - hypothetical protein MTH1862 29 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 15678789 Common - endonuclease III MTH764 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 15679415 Nonpathogen - hypothetical protein MTH1416 3 None None None 15678730 Common - 2-oxoisovalerate oxidoreductase, gamma subunit MTH703 11 COG1146 COG1146, Ferredoxin Energy production and conversion 15679276 Common - TRK system potassium uptake protein TrkA MTH1265 185 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15678830 Common cbiD cobalt-precorrin-6A synthase MTH808 92 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 15679676 Nonpathogen rpl12p 50S ribosomal protein L12P MTH1682 33 COG2058 RPP1A, Ribosomal protein L12E/L44/L45/RPP1/RPP2 Translation, ribosomal structure and biogenesis 15679079 Common - hypothetical protein MTH1068 27 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 15678057 Common - preprotein translocase subunit SecY MTH26 49 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 15678104 Nonpathogen - hypothetical protein MTH76 1 None None None 15678736 Common - GMP synthase subunit A MTH709 241 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 15678072 Common eno phosphopyruvate hydratase MTH43 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 15678092 Common - hypothetical protein MTH63 12 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 15679529 Nonpathogen - hypothetical protein MTH1533 1 None None None 15679875 Common - cation efflux system protein (zinc/cadmium) MTH1893 209 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 15678839 Common - hypothetical protein MTH817 64 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 15678755 Common - proteasome-activating nucleotidase MTH728 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 15679341 Nonpathogen - hypothetical protein MTH1341 1 None None None 15679268 Nonpathogen - hypothetical protein MTH1257 1 None None None 15679454 Nonpathogen - hypothetical protein MTH1457 4 None None None 15679625 Common aksA trans-homoaconitate synthase MTH1630 218 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15678038 Common rpl22p 50S ribosomal protein L22P MTH7 100 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 15678742 Nonpathogen - hypothetical protein MTH715 3 None None None 15679251 Common - ferredoxin MTH1240 17 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15678330 Nonpathogen - hypothetical protein MTH302 1 None None None 15678486 Nonpathogen - hypothetical protein MTH458 8 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 15678970 Nonpathogen - hypothetical protein MTH952 6 COG1417 COG1417, Uncharacterized conserved protein Function unknown 15678573 Nonpathogen - hypothetical protein MTH545 2 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15678351 Nonpathogen - hypothetical protein MTH323 5 None None None 15679534 Nonpathogen - hypothetical protein MTH1538 2 None None None 15678286 Common - nucleoside diphosphate kinase MTH258 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 15679343 Common - imidazoleglycerol-phosphate synthase (cyclase) MTH1343 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 15678363 Common - galactosyl-transferase RfpB related protein MTH335 210 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15679328 Common - hypothetical protein MTH1328 68 COG1476 COG1476, Predicted transcriptional regulators Transcription 15679489 Common - 5'-nucleotidase MTH1492 130 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 15679028 Common - endonuclease IV MTH1010 45 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 15678201 Common - LPS biosynthesis RfbU related protein MTH173 230 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15679013 Common - lysyl endopeptidase MTH995 27 COG3291 COG3291, FOG: PKD repeat General function prediction only 15679203 Nonpathogen - hypothetical protein MTH1192 14 None None None 15679300 Common - coenzyme F420-reducing hydrogenase, gamma subunit MTH1298 64 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 15679060 Common pgk phosphoglycerate kinase MTH1042 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 15679504 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase MTH1507 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 15678339 Common - hypothetical protein MTH311 29 None None None 15678247 Nonpathogen - hypothetical protein MTH219 1 None None None 15678894 Common - porphobilinogen deaminase MTH874 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 15679836 Nonpathogen - hypothetical protein MTH1848 11 COG4046 COG4046, Uncharacterized protein conserved in archaea Function unknown 15678664 Nonpathogen - hypothetical protein MTH636 2 None None None 15678474 Common - sensory transduction regulatory protein MTH446 195 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15679824 Common - hypothetical protein MTH1836 24 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 15678995 Nonpathogen - endo-1,4-beta-glucanase related protein MTH977 5 None None None 15678945 Common - hypothetical protein MTH925 25 COG2014 COG2014, Uncharacterized conserved protein Function unknown 15679222 Common - hypothetical protein MTH1211 219 COG0628 PerM, Predicted permease General function prediction only 15678254 Common aspC aspartyl-tRNA synthetase MTH226 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15678922 Common - sensory transduction histidine kinase MTH902 207 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678136 Nonpathogen - hypothetical protein MTH108 1 None None None 15678880 Common - glucosamine--fructose-6-phosphate aminotransferase MTH860 234 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 15679805 Common - heat shock protein X related protein MTH1817 61 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15679802 Common - hypothetical protein MTH1814 198 COG0714 COG0714, MoxR-like ATPases General function prediction only 15678796 Common - hypothetical protein MTH771 138 COG0432 COG0432, Uncharacterized conserved protein Function unknown 15679369 Common - ABC transporter (ATP-binding protein) MTH1370 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15679284 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B MTH1280 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 15678181 Common - hypothetical protein MTH153 145 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15679672 Nonpathogen nusG transcription antitermination protein NusG MTH1678 34 COG0250 NusG, Transcription antiterminator Transcription 15678409 Nonpathogen - hypothetical protein MTH381 12 COG4743 COG4743, Predicted membrane protein Function unknown 15679662 Common - hypothetical protein MTH1668 31 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 15679362 Common - cobalamin biosynthesis protein N MTH1363 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15679863 Nonpathogen - hypothetical protein MTH1875 1 None None None 15679756 Nonpathogen - hypothetical protein MTH1768 33 COG1499 NMD3, NMD protein affecting ribosome stability and mRNA decay Translation, ribosomal structure and biogenesis 15678381 Nonpathogen - hypothetical protein MTH353 1 None None None 15678615 Common metG methionyl-tRNA synthetase MTH587 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678672 Common - collagenase MTH645 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15678494 Common - hypothetical protein MTH466 21 None None None 15679844 Common - sodium/proline symporter (proline permease) MTH1856 181 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 15678525 Common - hypothetical protein MTH497 26 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 15679195 Nonpathogen - hypothetical protein MTH1184 3 None None None 15679211 Nonpathogen - met-10+ related protein MTH1200 36 COG2520 COG2520, Predicted methyltransferase General function prediction only 15678415 Nonpathogen - hypothetical protein MTH387 4 COG4039 COG4039, Predicted membrane protein Function unknown 15678705 Nonpathogen - hypothetical protein MTH678 17 COG1382 GimC, Prefoldin, chaperonin cofactor Posttranslational modification, protein turnover, chaperones 15679041 Common - ribonuclease HII MTH1023 168 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 15678835 Nonpathogen - hypothetical protein MTH813 3 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 15678388 Common - sensory transduction histidine kinase MTH360 94 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15679184 Common - cell division inhibitor related protein MTH1173 79 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15679253 Nonpathogen - hypothetical protein MTH1242 2 None None None 15679089 Common - hypothetical protein MTH1078 7 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15678362 Common - perosamine synthetase MTH334 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15678591 Common - succinyl-CoA synthetase subunit alpha MTH563 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 15679877 Common - hypothetical protein MTH1895 78 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15679146 Common - methyl viologen-reducing hydrogenase, gamma subunit MTH1135 54 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 15678800 Common - methionine synthase MTH775 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 15679093 Common - hypothetical protein MTH1082 29 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 15679499 Common sdhA succinate dehydrogenase flavoprotein subunit MTH1502 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 15679687 Common radB DNA repair and recombination protein RadB MTH1693 243 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 15679186 Common - hypothetical protein MTH1175 36 COG1433 COG1433, Uncharacterized conserved protein Function unknown 15679781 Common - hypothetical protein MTH1793 19 COG0546 Gph, Predicted phosphatases General function prediction only 15678174 Common - precorrin-8W decarboxylase MTH146 129 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 15678630 Common - precorrin-3 methylase MTH602 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 15679563 Common - catalytic subunit of nitrate reductase (flp) MTH1567 174 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15678602 Common - hypothetical protein MTH574 79 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 15679591 Common - methylthioadenosine phosphorylase MTH1596 148 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 15679613 Nonpathogen - hypothetical protein MTH1618 25 COG2023 RPR2, RNase P subunit RPR2 Translation, ribosomal structure and biogenesis 15678960 Common - type I restriction enzyme MTH940 138 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 15678815 Common - acetyl-CoA acetyltransferase MTH793 178 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 15679424 Common - O-sialoglycoprotein endopeptidase/protein kinase MTH1425 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 15678848 Nonpathogen - hypothetical protein MTH828 18 COG1326 COG1326, Uncharacterized archaeal Zn-finger protein General function prediction only 15678445 Common - homoserine dehydrogenase MTH417 215 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 15678584 Common - magnesium chelatase subunit ChlI MTH556 83 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 15679239 Common - hypothetical protein MTH1228 56 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15678856 Common - UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase MTH836 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 15678424 Nonpathogen - hypothetical protein MTH396 4 COG4084 COG4084, Uncharacterized protein conserved in archaea Function unknown 15679813 Common - cell surface glycoprotein MTH1825 33 None None None 15679052 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta MTH1034 113 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 15678515 Common - DNA helicase related protein MTH487 93 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 15679293 Common - heat shock protein GrpE MTH1289 227 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15679772 Common - Mg-protoporphyrin IX monomethyl ester oxidative cyclase MTH1784 144 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15679166 Common - Na+/Ca+ exchanging protein related MTH1155 130 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 15679233 Common - inosine-5'-monophosphate dehydrogenase related protein I MTH1222 163 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 15678373 Common - pyruvate formate-lyase 2 activating enzyme MTH345 45 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15678783 Common - S-D-lactoylglutathione methylglyoxal lyase MTH758 65 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 15679702 Common - acetyl-CoA decarbonylase/synthase complex subunit alpha MTH1708 19 COG1152 CdhA, CO dehydrogenase/acetyl-CoA synthase alpha subunit Energy production and conversion 15679023 Common - hypothetical protein MTH1005 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 15679475 Common - hypothetical protein MTH1478 56 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 15679654 Common - tryptophan synthase subunit beta MTH1659 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 15679153 Nonpathogen - H(2)-dependent methylenetetrahydromethanopterin dehydrogenase MTH1142 6 COG4074 Mth, H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase Energy production and conversion 15679373 Common - phosphoribosylformylglycinamidine synthase II MTH1374 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 15679646 Nonpathogen - hypothetical protein MTH1651 1 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15679245 Nonpathogen - hypothetical protein MTH1234 1 None None None 15678437 Nonpathogen - hypothetical protein MTH409 2 COG2445 COG2445, Uncharacterized conserved protein Function unknown 15678171 Common - molybdopterin-guanine dinucleotide biosynthesis MobA related protein MTH143 105 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 15679100 Nonpathogen - hypothetical protein MTH1089 1 None None None 15678668 Nonpathogen - hypothetical protein MTH641 40 COG1833 COG1833, Uncharacterized conserved protein Function unknown 15678637 Nonpathogen - hypothetical protein MTH609 23 COG1860 COG1860, Uncharacterized protein conserved in archaea Function unknown 15678769 Common - hypothetical protein MTH743 40 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 15678045 Nonpathogen rpl24p 50S ribosomal protein L24P MTH14 34 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 15678274 Common - twitching mobility (PilT) related protein MTH246 57 COG1855 COG1855, ATPase (PilT family) General function prediction only 15678980 Common - citrate synthase MTH962 188 COG0372 GltA, Citrate synthase Energy production and conversion 15678644 Common - hypothetical protein MTH616 67 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 15679009 Nonpathogen - hypothetical protein MTH991 2 None None None 15679080 Common - pyruvate formate lyase activating protein MTH1069 62 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 15678318 Nonpathogen - hypothetical protein MTH290 1 None None None 15679831 Nonpathogen - hypothetical protein MTH1843 12 COG4742 COG4742, Predicted transcriptional regulator Transcription 15678787 Nonpathogen - hypothetical protein MTH762 7 COG1689 COG1689, Uncharacterized protein conserved in archaea Function unknown 15679636 Nonpathogen - hypothetical protein MTH1641 1 None None None 15679867 Common - heterodisulfide reductase, subunit B MTH1879 91 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 15679384 Nonpathogen - replication factor A MTH1385 23 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 15678565 Common - 2-oxoacid ferredoxin oxidoreductase subunit beta MTH537 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 15678617 Nonpathogen - hypothetical protein MTH589 7 COG1710 COG1710, Uncharacterized protein conserved in archaea Function unknown 15678297 Common - argininosuccinate lyase MTH269 240 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 15679550 Common - tungsten formylmethanofuran dehydrogenase, subunit F MTH1554 182 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15678690 Common - ammonium transporter MTH663 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 15679135 Common - sensory transduction histidine kinase MTH1124 72 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678695 Common - hypothetical protein MTH668 6 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15679121 Nonpathogen - hypothetical protein MTH1110 5 COG4075 COG4075, Uncharacterized conserved protein, homolog of nitrogen regulatory protein PII Function unknown 15679287 Common - phosphoribosyl-AMP cyclohydrolase homolog MTH1283 133 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 15679495 Common - hypothetical protein MTH1498 57 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 15678697 Nonpathogen - hypothetical protein MTH670 6 COG4744 COG4744, Uncharacterized conserved protein Function unknown 15678925 Common - hypothetical protein MTH905 26 COG1268 BioY, Uncharacterized conserved protein General function prediction only 15679324 Nonpathogen - hypothetical protein MTH1324 22 COG1460 COG1460, Uncharacterized protein conserved in archaea Function unknown 15679097 Common - hypothetical protein MTH1086 109 COG1203 COG1203, Predicted helicases General function prediction only 15678290 Nonpathogen - hypothetical protein MTH262 17 COG1412 COG1412, Uncharacterized proteins of PilT N-term./Vapc superfamily General function prediction only 15678251 Nonpathogen - hypothetical protein MTH223 7 COG2403 COG2403, Predicted GTPase General function prediction only 15678770 Common - delta-aminolevulinic acid dehydratase MTH744 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 15679643 Common - dihydrolipoamide dehydrogenase MTH1648 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 15678258 Nonpathogen - hypothetical protein MTH230 4 None None None 15679033 Common - methyl coenzyme M reductase system, component A2 MTH1015 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 15679389 Common ribH riboflavin synthase subunit beta MTH1390 186 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 15678060 Nonpathogen rpl34e 50S ribosomal protein L34e MTH29 17 COG2174 RPL34A, Ribosomal protein L34E Translation, ribosomal structure and biogenesis 15678166 Common - GlcNAc-phosphatidylinositol related biosynthetic protein MTH138 157 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15679282 Nonpathogen - hypothetical protein MTH1278 5 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15679433 Nonpathogen - hypothetical protein MTH1436 1 None None None 15678679 Common - ribonucleotide reductase, large subunit MTH652 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15678948 Common - cobalamin biosynthesis protein N MTH928 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15678811 Common - cobyric acid synthase MTH787 164 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 15679555 Common - tungsten formylmethanofuran dehydrogenase, subunit B MTH1559 133 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 15679405 Common - fuculose-1-phosphate aldolase MTH1406 163 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 15678779 Common - hypothetical protein MTH754 100 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 15678124 Common - hypothetical protein MTH96 2 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15678503 Common - hypothetical protein MTH475 10 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 15678067 Common - DNA-directed RNA polymerase subunit D MTH37 37 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 15679353 Common - NADH oxidase MTH1354 246 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 15678807 Common hypA hydrogenase nickel incorporation protein MTH783 89 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 15678369 Common - coenzyme F420-reducing hydrogenase, beta subunit homolog MTH341 50 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 15679142 Nonpathogen - methyl coenzyme M reductase II, D protein MTH1131 14 COG4055 McrD, Methyl coenzyme M reductase, subunit D Coenzyme metabolism 15679501 Nonpathogen - hypothetical protein MTH1504 2 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 15679084 Common - cation antiporter MTH1073 107 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 15679678 Common - conserved protein (contains ferredoxin domain) MTH1684 44 COG1900 COG1900, Uncharacterized conserved protein Function unknown 15679482 Common - serine/threonine protein kinase related protein MTH1485 139 COG1520 COG1520, FOG: WD40-like repeat Function unknown 15679117 Common - ferredoxin MTH1106 86 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15679574 Nonpathogen - hypothetical protein MTH1579 12 COG4742 COG4742, Predicted transcriptional regulator Transcription 15678270 Common - shikimate 5-dehydrogenase MTH242 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 15679449 Common - hypothetical protein MTH1452 40 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 15678115 Common - surface protease related protein MTH87 17 COG3291 COG3291, FOG: PKD repeat General function prediction only 15679214 Common - cleavage and polyadenylation specificity factor MTH1203 157 COG1782 COG1782, Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain General function prediction only 15679279 Nonpathogen - hypothetical protein MTH1270 22 COG1591 COG1591, Holliday junction resolvase - archaeal type DNA replication, recombination, and repair 15678716 Nonpathogen - hypothetical protein MTH689 20 COG1325 COG1325, Predicted exosome subunit Translation, ribosomal structure and biogenesis 15679463 Common - hypothetical protein MTH1466 59 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 15678909 Nonpathogen - hypothetical protein MTH889 23 COG1888 COG1888, Uncharacterized protein conserved in archaea Function unknown 15679027 Common - glyceraldehyde-3-phosphate dehydrogenase MTH1009 41 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15678198 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase MTH170 208 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 15678314 Nonpathogen - hypothetical protein MTH286 1 None None None 15678531 Common - hypothetical protein MTH503 23 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 15679603 Common - signal recognition particle protein (docking protein) MTH1608 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 15679719 Common - phosphate-binding protein PstS MTH1727 200 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 15679668 Common - hypothetical protein MTH1674 24 COG1809 COG1809, Uncharacterized conserved protein Function unknown 15679716 Common - phosphate transport system regulator related protein MTH1724 59 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 15678896 Common - orotate phosphoribosyltransferase MTH876 24 COG0856 COG0856, Orotate phosphoribosyltransferase homologs Nucleotide transport and metabolism 15678279 Common - tryptophanyl-tRNA synthetase MTH251 106 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678587 Common - hypothetical protein MTH559 30 COG1852 COG1852, Uncharacterized conserved protein Function unknown 15678118 Nonpathogen - hypothetical protein MTH90 1 None None None 15678976 Common - ATP synthase, subunit E MTH958 14 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 15678158 Common - cobalt transport protein CbiM MTH130 70 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 15678070 Nonpathogen - DNA-directed RNA polymerase subunit N MTH40 34 COG1644 RPB10, DNA-directed RNA polymerase, subunit N (RpoN/RPB10) Transcription 15678094 Nonpathogen - hypothetical protein MTH65 1 None None None 15679164 Nonpathogen - hypothetical protein MTH1153 14 COG4065 COG4065, Uncharacterized protein conserved in archaea Function unknown 15679880 Common - oligosaccharyl transferase MTH1898 11 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15678106 Nonpathogen - hypothetical protein MTH78 1 None None None 15679438 Nonpathogen - hypothetical protein MTH1441 13 COG4020 COG4020, Uncharacterized protein conserved in archaea Function unknown 15678394 Nonpathogen - hypothetical protein MTH366 2 None None None 15679062 Common - DNA-directed RNA polymerase subunit beta'' MTH1049 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 15678748 Common - hypothetical protein MTH721 9 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15679627 Common - hypothetical protein MTH1632 14 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 15678950 Nonpathogen - hypothetical protein MTH930 5 None None None 15679513 Common - cation-transporting P-ATPase PacL MTH1516 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 15679123 Common - cobalamin (5'-phosphate) synthase MTH1112 27 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 15678225 Nonpathogen - hypothetical protein MTH197 1 None None None 15678753 Nonpathogen - hypothetical protein MTH726 4 COG3428 COG3428, Predicted membrane protein Function unknown 161484928 Common - hydroxylamine reductase MTH1453 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 15678461 Nonpathogen - hypothetical protein MTH433 25 COG1931 COG1931, Uncharacterized protein conserved in archaea Function unknown 15679696 Common - secretory protein kinase MTH1702 228 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 15678378 Nonpathogen - hypothetical protein MTH350 1 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 15678571 Nonpathogen - hypothetical protein MTH543 2 None None None 15678653 Nonpathogen - hypothetical protein MTH625 1 None None None 15678309 Common - hypothetical protein MTH281 68 COG1695 COG1695, Predicted transcriptional regulators Transcription 15678282 Nonpathogen - histone HMtB MTH254 24 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 15679721 Common - phosphate transporter permease PstC MTH1729 231 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 15679561 Common - nitrogenase iron-molybdenum cofactor biosynthesis protein NifE MTH1565 67 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15678488 Common - phosphoenolpyruvate synthase homolog MTH460 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15679767 Nonpathogen - hypothetical protein MTH1779 1 None None None 15678990 Common - hypothetical protein MTH972 20 COG4021 COG4021, Uncharacterized conserved protein Function unknown 15679290 Common - phosphoribosylaminoimidazole carboxylase related protein MTH1286 66 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 15678452 Nonpathogen - hypothetical protein MTH424 1 None None None 15679740 Nonpathogen - hypothetical protein MTH1748 1 None None None 15678741 Common - magnesium chelatase subunit MTH714 93 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15679658 Nonpathogen - hypothetical protein MTH1664 6 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 15678564 Common - 2-oxoacid:ferredoxin oxidoreductase, alpha subunit MTH536 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15678884 Nonpathogen - hypothetical protein MTH864 9 None None None 15678079 Common - bifunctional short chain isoprenyl diphosphate synthase MTH50 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15679728 Common - formate hydrogenlyase, iron-sulfur subunit 2 MTH1736 158 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15678676 Nonpathogen - small nuclear ribonucleoprotein MTH649 32 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 15679309 Nonpathogen rps27e 30S ribosomal protein S27e MTH1309 34 COG2051 RPS27A, Ribosomal protein S27E Translation, ribosomal structure and biogenesis 15679274 Nonpathogen - hypothetical protein MTH1263 10 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 15679017 Common - N-terminal acetyltransferase complex, subunit ARD1 MTH999 179 COG0456 RimI, Acetyltransferases General function prediction only 15679826 Nonpathogen - hypothetical protein MTH1838 3 COG2450 COG2450, Uncharacterized conserved protein Function unknown 15678354 Nonpathogen - hypothetical protein MTH326 5 None None None 15678235 Nonpathogen - 30S ribosomal protein S8e MTH207 34 COG2007 RPS8A, Ribosomal protein S8E Translation, ribosomal structure and biogenesis 15679522 Common - hydrogenase expression/formation protein HypE related protein MTH1525 104 COG1973 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15679401 Nonpathogen - hypothetical protein MTH1402 20 COG3273 COG3273, Uncharacterized conserved protein Function unknown 15679314 Nonpathogen - transcription elongation factor TFIIS MTH1314 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 15679752 Common - sensory transduction regulatory protein MTH1764 208 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 15678337 Nonpathogen - hypothetical protein MTH309 1 None None None 15678902 Common - hypothetical protein MTH882 31 COG0730 COG0730, Predicted permeases General function prediction only 15678302 Nonpathogen - hypothetical protein MTH274 1 None None None 15678910 Nonpathogen - hypothetical protein MTH890 11 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 15678459 Nonpathogen - hypothetical protein MTH431 3 None None None 15679072 Common rps10p 30S ribosomal protein S10P MTH1059 234 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 15679689 Common - putative ATPase RIL MTH1695 249 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 15679412 Common pyrB aspartate carbamoyltransferase catalytic subunit MTH1413 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 15678876 Common - zinc metalloproteinase MTH856 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15678772 Common - endonuclease III related protein (probably non-iron-sulfur homolog) MTH746 102 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 15678476 Common - hypothetical protein MTH448 32 COG1415 COG1415, Uncharacterized conserved protein Function unknown 15679201 Nonpathogen - N(2),N(2)-dimethylguanosine tRNA methyltransferase MTH1190 38 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 15679367 Nonpathogen - hypothetical protein MTH1368 36 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15678639 Common - prolyl-tRNA synthetase MTH611 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15679048 Nonpathogen - hypothetical protein MTH1030 6 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 15678252 Nonpathogen - hypothetical protein MTH224 16 COG1745 COG1745, Predicted metal-binding protein General function prediction only 15679477 Nonpathogen - hypothetical protein MTH1480 19 COG1967 COG1967, Predicted membrane protein Function unknown 15679800 Common - hypothetical protein MTH1812 67 COG1971 COG1971, Predicted membrane protein Function unknown 15679422 Nonpathogen rps15p 30S ribosomal protein S15P MTH1423 34 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 15678344 Nonpathogen - hypothetical protein MTH316 2 None None None 15678281 Common - threonine synthase MTH253 181 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 15679429 Common - branched-chain amino-acid aminotransferase MTH1430 219 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15678798 Common - N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase MTH773 27 COG3252 COG3252, Methenyltetrahydromethanopterin cyclohydrolase Coenzyme metabolism 15678168 Common - hypothetical protein MTH140 96 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 15678407 Common - O-antigen transporter related protein MTH379 164 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15678969 Nonpathogen - hypothetical protein MTH951 1 None None None 15678435 Nonpathogen - hypothetical protein MTH407 1 None None None 15679664 Nonpathogen - hypothetical protein MTH1670 6 COG4071 COG4071, Uncharacterized protein conserved in archaea Function unknown 15679031 Common - hypothetical protein MTH1013 129 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 15679443 Common - ornithine carbamoyltransferase MTH1446 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 15679597 Common - acetolactate synthase, large subunit homolog MTH1602 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15679674 Common rpl1P 50S ribosomal protein L1P MTH1680 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 15679227 Common - pantothenate metabolism flavoprotein MTH1216 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 15679249 Common - formate hydrogenlyase, subunit 5 MTH1238 198 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 15678396 Common - glycerol-3-phosphate dehydrogenase (NAD) MTH368 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15679188 Common - hypothetical protein MTH1177 25 COG1433 COG1433, Uncharacterized conserved protein Function unknown 15678496 Common - sensory transduction histidine kinase MTH468 100 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15679360 Common - ferrous iron transport protein B MTH1361 160 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 15678837 Nonpathogen - hypothetical protein MTH815 3 COG1873 COG1873, Uncharacterized conserved protein Function unknown 15678553 Nonpathogen - hypothetical protein MTH525 1 None None None 15678195 Common - uroporphyrin-III C-methyltransferase MTH167 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 15678417 Nonpathogen - hypothetical protein MTH389 8 COG4037 COG4037, Predicted membrane protein Function unknown 15678205 Nonpathogen nac nascent polypeptide-associated complex protein MTH177 33 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 15679461 Nonpathogen - F420-dependent methylenetetrahydromethanopterin dehydrogenase MTH1464 15 COG1927 Mtd, Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase Energy production and conversion 15679131 Common - nifH / minD related protein MTH1120 39 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 15679599 Common - acetyl-CoA synthetase MTH1604 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15678323 Nonpathogen - hypothetical protein MTH295 1 None None None 15679326 Common ksgA dimethyladenosine transferase MTH1326 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 15679532 Nonpathogen - DNA polymerase II large subunit MTH1536 25 COG1933 COG1933, Archaeal DNA polymerase II, large subunit DNA replication, recombination, and repair 15678546 Common - hypothetical protein MTH518 11 COG3815 COG3815, Predicted membrane protein Function unknown 15679581 Common - pyruvate formate-lyase activating enzyme MTH1586 105 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15678121 Nonpathogen - hypothetical protein MTH93 1 None None None 15678760 Nonpathogen - hypothetical protein MTH733 4 None None None 15678651 Common - hypothetical protein MTH623 36 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 15678935 Nonpathogen - hypothetical protein MTH915 2 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 15678062 Nonpathogen - 50S ribosomal protein L14e MTH31 18 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 15678084 Nonpathogen - hypothetical protein MTH55 2 COG5643 COG5643, Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E General function prediction only 15678947 Nonpathogen - ferredoxin MTH927 7 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15679506 Common - divalent cation tolerance protein MTH1509 119 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 15678288 Nonpathogen - 30S ribosomal protein S6e MTH260 34 COG2125 RPS6A, Ribosomal protein S6E (S10) Translation, ribosomal structure and biogenesis 15678206 Common - Icc related protein MTH178 110 COG1409 Icc, Predicted phosphohydrolases General function prediction only 15678212 Common - 3-isopropylmalate dehydrogenase MTH184 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 15679243 Common - homoserine dehydrogenase MTH1232 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 15679649 Nonpathogen - hypothetical protein MTH1654 21 COG2150 COG2150, Predicted regulator of amino acid metabolism, contains ACT domain General function prediction only 15679790 Common - ATP-dependent helicase MTH1802 181 COG1201 Lhr, Lhr-like helicases General function prediction only 15679266 Nonpathogen - hypothetical protein MTH1255 1 None None None 15678138 Nonpathogen - hypothetical protein MTH110 1 None None None 15678277 Common - hypothetical protein MTH249 49 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 15678375 Common - O-antigen transporter MTH347 103 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15679155 Nonpathogen - hypothetical protein MTH1144 6 COG4019 COG4019, Uncharacterized protein conserved in archaea Function unknown 15679375 Common - S-adenosylmethionine synthetase MTH1376 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 15679900 Nonpathogen - possible protein methyltransferase MTH1918 31 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 15679704 Common - acetyl-CoA decarbonylase/synthase complex subunit beta MTH1710 19 COG1614 CdhC, CO dehydrogenase/acetyl-CoA synthase beta subunit Energy production and conversion 15679601 Common - hypothetical protein MTH1606 5 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 15679082 Common - phosphoglycolate phosphatase MTH1071 143 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 15678711 Nonpathogen - exosome complex RNA-binding protein Rrp4 MTH684 24 COG1097 RRP4, RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) Translation, ribosomal structure and biogenesis 15679761 Common - cell division protein J MTH1773 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 15678642 Common - transcriptional regulator MTH614 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 15678043 Common rps17p 30S ribosomal protein S17P MTH12 38 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 15679546 Common moaA molybdenum cofactor biosynthesis protein A MTH1550 206 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15679770 Nonpathogen - hypothetical protein MTH1782 1 None None None 15678141 Nonpathogen - arylsulfatase regulatory protein MTH113 11 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 15679262 Common - putative monovalent cation/H+ antiporter subunit E MTH1251 42 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 15678533 Common - potassium channel related protein MTH505 55 None None None 15678822 Common - dihydrodipicolinate reductase MTH800 218 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 15678263 Common - hypothetical protein MTH235 221 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 15678703 Common - hypothetical protein MTH676 24 COG3153 COG3153, Predicted acetyltransferase General function prediction only 15678846 Common - hypothetical protein MTH826 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15678439 Common - cadmium efflux ATPase MTH411 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15679879 Common - NTPase MTH1897 37 COG1986 COG1986, Uncharacterized conserved protein Function unknown 15679893 Common - hypothetical protein MTH1911 14 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 15678632 Common - adhesion protein MTH604 175 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15679095 Common - hypothetical protein MTH1084 96 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 15678336 Nonpathogen - hypothetical protein MTH308 6 COG3339 COG3339, Uncharacterized conserved protein Function unknown 15678666 Nonpathogen - hypothetical protein MTH639 27 COG2090 COG2090, Uncharacterized protein conserved in archaea Function unknown 15678516 Common - hypothetical protein MTH488 32 None None None 15679108 Nonpathogen - hypothetical protein MTH1097 12 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 15678236 Common - DNA-dependent DNA polymerase family B (PolB2) MTH208 48 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 15678360 Common - LPS biosynthesis RfbU related protein MTH332 221 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15678718 Nonpathogen - hypothetical protein MTH691 9 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 15678986 Nonpathogen - hypothetical protein MTH968 1 None None None 15678249 Common - hypothetical protein MTH221 36 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 15678858 Nonpathogen - hypothetical protein MTH838 17 COG2433 COG2433, Uncharacterized conserved protein Function unknown 15678861 Common - hypothetical protein MTH841 125 COG2510 COG2510, Predicted membrane protein Function unknown 15679050 Common - ferredoxin (putative 2-oxoglutarate oxidoreductase, delat subunit) MTH1032 51 COG1146 COG1146, Ferredoxin Energy production and conversion 15679237 Common - inosine-5'-monophosphate dehydrogenase related protein V MTH1226 188 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 15678791 Common - 3-phosphoshikimate 1-carboxyvinyltransferase MTH766 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 15679232 Nonpathogen - hypothetical protein MTH1221 19 COG1423 COG1423, ATP-dependent DNA ligase, homolog of eukaryotic ligase III DNA replication, recombination, and repair 15679616 Common - GTP-binding protein, GTP1/OBG family MTH1621 249 COG1163 DRG, Predicted GTPase General function prediction only 15679731 Common - pyruvate oxidoreductase, alpha subunit MTH1739 134 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15678604 Common - hypothetical protein MTH576 21 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 15678426 Common - formate hydrogenlyase, subunit 5 MTH398 193 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 15678962 Common - type I restriction modification enzyme, subunit M MTH942 162 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15679416 Common - hypothetical protein MTH1417 24 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 15678428 Nonpathogen - polyferredoxin MTH400 2 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 15678041 Common - translation initiation factor Sui1 MTH10 56 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 15679303 Nonpathogen - hypothetical protein MTH1301 1 COG3212 COG3212, Predicted membrane protein Function unknown 15679755 Common - tyrosyl-tRNA synthetase MTH1767 183 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678978 Common - V-type ATP synthase subunit I MTH960 49 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 15679119 Common - hypothetical protein MTH1108 178 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 15679726 Common - phosphate transport system regulator MTH1734 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 15679691 Nonpathogen - peptidyl-tRNA hydrolase MTH1697 34 COG1990 COG1990, Uncharacterized conserved protein Function unknown 15679419 Nonpathogen - hypothetical protein MTH1420 1 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 15679111 Common - hypothetical protein MTH1100 10 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 15678160 Common - cobalt transport protein Q MTH132 73 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15678448 Nonpathogen - hypothetical protein MTH420 5 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15678126 Nonpathogen - hypothetical protein MTH98 1 None None None 15678304 Nonpathogen - hypothetical protein MTH276 1 None None None 15679588 Nonpathogen - 30S ribosomal protein S3Ae MTH1593 34 COG1890 RPS1A, Ribosomal protein S3AE Translation, ribosomal structure and biogenesis 15678735 Common - thioredoxin reductase MTH708 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15679272 Nonpathogen - hypothetical protein MTH1261 25 COG0392 COG0392, Predicted integral membrane protein Function unknown 15678530 Common - hypothetical protein MTH502 20 COG1700 COG1700, Uncharacterized conserved protein Function unknown 15679403 Nonpathogen - hypothetical protein MTH1404 3 None None None 15678357 Nonpathogen - hypothetical protein MTH329 3 None None None 15679410 Nonpathogen - hypothetical protein MTH1411 1 None None None 15678457 Nonpathogen - hypothetical protein MTH429 1 None None None 15679618 Common - oligosaccharyl transferase STT3 subunit related protein MTH1623 21 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15678968 Nonpathogen - hypothetical protein MTH950 1 None None None 15678751 Common - methyltransferase related protein MTH724 62 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 15679871 Nonpathogen - 2-phosphoglycerate kinase MTH1883 14 COG2074 COG2074, 2-phosphoglycerate kinase Carbohydrate transport and metabolism 15678624 Nonpathogen - hypothetical protein MTH596 3 None None None 15678100 Common - O-linked GlcNAc transferase MTH72 193 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15679177 Nonpathogen - methyl coenzyme M reductase I, C protein MTH1166 14 COG4056 McrC, Methyl coenzyme M reductase, subunit C Coenzyme metabolism 15678752 Common - hypothetical protein MTH725 73 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15678510 Nonpathogen - H+-transporting ATPase MTH482 13 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 15678874 Common - ferredoxin MTH854 88 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 15679382 Common radA DNA repair and recombination protein RadA MTH1383 241 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 15678299 Nonpathogen - hypothetical protein MTH271 9 COG1365 COG1365, Predicted ATPase (PP-loop superfamily) General function prediction only 15678391 Nonpathogen - hypothetical protein MTH363 1 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15679629 Common - transcriptional control factor (enhancer-binding protein) MTH1634 101 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 15678662 Common - UTP--glucose-1-phosphate uridylyltransferase MTH634 234 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15678941 Common - anion transport system permease protein MTH921 202 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 15678567 Nonpathogen - hypothetical protein MTH539 1 None None None 15678273 Common hisI phosphoribosyl-AMP cyclohydrolase MTH245 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 15678904 Common - teichoic acid biosynthesis related protein MTH884 66 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 15678493 Common - hypothetical protein MTH465 50 COG2035 COG2035, Predicted membrane protein Function unknown 15678107 Nonpathogen - hypothetical protein MTH79 1 None None None 15679163 Common - hypothetical protein MTH1152 63 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 15679576 Nonpathogen - hypothetical protein MTH1581 4 COG4085 COG4085, Predicted RNA-binding protein, contains TRAM domain General function prediction only 15679690 Nonpathogen - histone HMtA2 MTH1696 24 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 15678032 Nonpathogen - hypothetical protein MTH1 22 COG2106 COG2106, Uncharacterized conserved protein Function unknown 15678034 Common rpl4lp 50S ribosomal protein L4P MTH3 43 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 15679277 Nonpathogen - hypothetical protein MTH1266 1 None None None 15678824 Common - aspartate kinase MTH802 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15679038 Nonpathogen - IMP cyclohydrolase MTH1020 13 COG3363 COG3363, Archaeal IMP cyclohydrolase Nucleotide transport and metabolism 15679706 Common - acetyl-CoA decarbonylase/synthase complex subunit delta MTH1712 20 COG2069 CdhD, CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) Energy production and conversion 15679075 Nonpathogen - hypothetical protein MTH1064 19 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15679663 Nonpathogen - transcription initiation factor E subunit alpha MTH1669 31 COG1675 TFA1, Transcription initiation factor IIE, alpha subunit Transcription 15679886 Nonpathogen - hypothetical protein MTH1904 14 COG3365 COG3365, Uncharacterized protein conserved in archaea Function unknown 15678223 Common - efflux pump antibiotic resistance protein MTH195 227 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15679209 Common cofG FO synthase subunit 1 MTH1198 47 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 15678974 Common - V-type ATP synthase subunit F MTH956 26 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 15678683 Common - ATP-dependent RNA helicase related protein MTH656 162 COG1202 COG1202, Superfamily II helicase, archaea-specific General function prediction only 15679679 Common - hypothetical protein MTH1685 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 15678622 Common - hypothetical protein MTH594 56 COG2229 COG2229, Predicted GTPase General function prediction only 15679516 Nonpathogen - hypothetical protein MTH1519 1 None None None 15679312 Nonpathogen - proliferating-cell nuclear antigen MTH1312 34 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 15678081 Common - L,L-diaminopimelate aminotransferase MTH52 230 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15678097 Nonpathogen - hypothetical protein MTH69 1 None None None 15678356 Nonpathogen - hypothetical protein MTH328 5 None None None 15679351 Nonpathogen - possible rubredoxin MTH1352 1 None None None 15679229 Nonpathogen - hypothetical protein MTH1218 3 None None None 15678215 Common - hypothetical protein MTH187 27 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15678319 Nonpathogen - hypothetical protein MTH291 1 None None None 15678077 Common - isopentenyl pyrophosphate isomerase MTH48 83 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 15679717 Common - hypothetical protein MTH1725 15 None None None 15678818 Common - hypothetical protein MTH796 82 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 15679261 Nonpathogen - putative monovalent cation/H+ antiporter subunit F MTH1250 3 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 15679742 Nonpathogen - hypothetical protein MTH1750 3 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 15679484 Common - ABC transporter (ATP-binding MTH1487 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15679769 Nonpathogen - hypothetical protein MTH1781 5 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 15679200 Common - hypothetical protein MTH1189 21 None None None 15679354 Common - arsenate reductase MTH1355 142 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 15678113 Nonpathogen - hypothetical protein MTH85 1 None None None 15679878 Nonpathogen - phosphopantetheine adenylyltransferase MTH1896 28 COG1019 COG1019, Predicted nucleotidyltransferase General function prediction only 15678228 Common - cobalamin biosynthesis protein M related protein MTH200 60 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 15678326 Nonpathogen - DNA-dependent RNA polymerase, subunit A' MTH298 34 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15678898 Nonpathogen - peptide chain release factor 1 MTH878 36 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 15678702 Nonpathogen - hypothetical protein MTH675 3 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 15679861 Common - met-10+ protein MTH1873 47 COG2520 COG2520, Predicted methyltransferase General function prediction only 15679020 Common - cobalamin biosynthesis protein J MTH1002 80 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 15678248 Common - flavoprotein A homolog (II) MTH220 79 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15678517 Nonpathogen - hypothetical protein MTH489 1 None None None 15678543 Nonpathogen - hypothetical protein MTH515 8 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15679852 Common - phosphoribosylformylglycinamidine synthase II related protein MTH1864 171 COG2144 COG2144, Selenophosphate synthetase-related proteins General function prediction only 15678936 Nonpathogen - hypothetical protein MTH916 16 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 15678175 Common - phenylacrylic acid decarboxylase MTH147 153 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 15679833 Nonpathogen - hypothetical protein MTH1845 1 None None None 15678724 Common - hypothetical protein MTH697 17 COG1036 COG1036, Archaeal flavoproteins Energy production and conversion 15679191 Nonpathogen - hypothetical protein MTH1180 14 COG4052 COG4052, Uncharacterized protein related to methyl coenzyme M reductase subunit C General function prediction only 15679568 Nonpathogen - hypothetical protein MTH1573 3 None None None 15678693 Common - pyridoxine biosynthesis protein MTH666 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 15678775 Common - hypothetical protein MTH749 8 COG2966 COG2966, Uncharacterized conserved protein Function unknown 15678156 Nonpathogen - hypothetical protein MTH128 3 None None None 15678790 Common - GTP-binding protein Rab related protein MTH765 70 COG2229 COG2229, Predicted GTPase General function prediction only 15678055 Nonpathogen rpl30p 50S ribosomal protein L30P MTH24 34 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 15678885 Nonpathogen - hypothetical protein MTH865 11 COG4746 COG4746, Uncharacterized protein conserved in archaea Function unknown 15678658 Nonpathogen - hypothetical protein MTH630 1 COG2510 COG2510, Predicted membrane protein Function unknown 15678443 Nonpathogen gatC aspartyl/glutamyl-tRNA amidotransferase subunit C MTH415 4 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 15679630 Nonpathogen - hypothetical protein MTH1635 7 COG4073 COG4073, Uncharacterized protein conserved in archaea Function unknown 15678537 Nonpathogen - hypothetical protein MTH509 1 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15679682 Nonpathogen - hypothetical protein MTH1688 6 COG2454 COG2454, Uncharacterized conserved protein Function unknown 15678194 Common - uroporphyrinogen III synthase MTH166 103 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 15679337 Common - N-acetylornithine aminotransferase MTH1337 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 15679431 Common - hypothetical protein MTH1434 4 None None None 15678919 Common - transcriptional regulator MTH899 135 COG0640 ArsR, Predicted transcriptional regulators Transcription 15679556 Common nifH nitrogenase reductase MTH1560 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 15679056 Common - hypothetical protein MTH1038 12 COG4086 COG4086, Predicted secreted protein Function unknown 15679524 Common - coenzyme F390 synthetase I MTH1528 110 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 15678069 Common - ribosomal protein S16 (E.coli S9) MTH39 77 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 15678927 Common - hypothetical protein MTH907 34 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 15679745 Common - alpha,alpha-trehalose-phosphate synthase MTH1757 95 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 15678241 Common - ferrous iron transport protein B MTH213 185 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 15678167 Common - heterodisulfide reductase HdrD related protein MTH139 80 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 15679760 Nonpathogen - hypothetical protein MTH1772 3 None None None 15678712 Nonpathogen - hypothetical protein MTH685 34 COG1500 COG1500, Predicted exosome subunit Translation, ribosomal structure and biogenesis 15679677 Common alaS alanyl-tRNA synthetase MTH1683 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15679835 Common dcd deoxycytidine triphosphate deaminase MTH1847 167 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 15678178 Common - hypothetical protein MTH150 48 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 15678154 Common - inosine-5'-monophosphate dehydrogenase related protein VII MTH126 188 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 15678450 Nonpathogen - hypothetical protein MTH422 1 COG1991 COG1991, Uncharacterized conserved protein Function unknown 15679085 Common - hypothetical protein MTH1074 76 None None None 15679595 Nonpathogen - hypothetical protein MTH1600 29 COG1634 COG1634, Uncharacterized Rossmann fold enzyme General function prediction only 15679213 Common - proteasome, beta subunit MTH1202 48 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 15679051 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit alpha MTH1033 128 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15678410 Nonpathogen - hypothetical protein MTH382 1 None None None 15679548 Common - formate dehydrogenase, alpha subunit homolog MTH1552 216 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 15678883 Nonpathogen - hypothetical protein MTH863 17 COG2457 COG2457, Uncharacterized conserved protein Function unknown 15679018 Nonpathogen - hypothetical protein MTH1000 12 COG1255 COG1255, Uncharacterized protein conserved in archaea Function unknown 15679230 Nonpathogen - hypothetical protein MTH1219 3 COG3889 COG3889, Predicted solute binding protein General function prediction only 15678588 Nonpathogen - hypothetical protein MTH560 26 COG1831 COG1831, Predicted metal-dependent hydrolase (urease superfamily) General function prediction only 15679242 Nonpathogen - hypothetical protein MTH1231 18 COG1665 COG1665, Uncharacterized protein conserved in archaea Function unknown 15678634 Common - manganese transport system membrane protein MTH606 190 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 15678203 Common - hypothetical protein MTH175 58 COG4121 COG4121, Uncharacterized conserved protein Function unknown 15679590 Common - hypothetical protein MTH1595 40 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15679784 Common - hypothetical protein MTH1796 39 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 15678987 Nonpathogen - hypothetical protein MTH969 4 None None None 15679421 Common - hypothetical protein MTH1422 36 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15678427 Common - polyferredoxin MTH399 110 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15678266 Common - tungsten formylmethanofuran dehydrogenase, subunit C homolog MTH238 29 COG2218 FwdC, Formylmethanofuran dehydrogenase subunit C Energy production and conversion 15678708 Nonpathogen rpl37ae 50S ribosomal protein L37Ae MTH681 34 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 15679358 Nonpathogen - hypothetical protein MTH1359 16 COG4871 COG4871, Uncharacterized protein conserved in archaea Function unknown 15678746 Nonpathogen - cell surface glycoprotein (s-layer protein) MTH719 12 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 15679392 Common - phosphoribosylaminoimidazole carboxylase MTH1393 230 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 15678420 Nonpathogen - hypothetical protein MTH392 2 None None None 15679762 Common - hypothetical protein MTH1774 80 COG0622 COG0622, Predicted phosphoesterase General function prediction only 15679181 Nonpathogen - hypothetical protein MTH1170 15 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 15679514 Nonpathogen - hypothetical protein MTH1517 1 None None None 15679096 Common - hypothetical protein MTH1085 35 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 15678867 Common - hypothetical protein MTH847 34 COG0716 FldA, Flavodoxins Energy production and conversion 15678596 Nonpathogen - hypothetical protein MTH568 2 None None None 15679811 Nonpathogen - hypothetical protein MTH1823 6 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15679697 Common - hypothetical protein MTH1703 56 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 15679604 Nonpathogen - prefoldin subunit alpha MTH1609 30 COG1730 GIM5, Predicted prefoldin, molecular chaperone implicated in de novo protein folding Posttranslational modification, protein turnover, chaperones 15678433 Common - polyferredoxin MTH405 167 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 15679776 Nonpathogen - hypothetical protein MTH1788 2 None None None 15679882 Nonpathogen - hypothetical protein MTH1900 1 None None None 15679816 Nonpathogen - hypothetical protein MTH1828 2 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 15679105 Common - circadian clock protein KaiC MTH1094 170 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 15679157 Common - hypothetical protein MTH1146 22 COG0327 COG0327, Uncharacterized conserved protein Function unknown 15678843 Nonpathogen - histone HMtA1 MTH821 20 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 15678242 Common - iron repressor MTH214 121 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 15678283 Nonpathogen rpl7ae 50S ribosomal protein L7Ae MTH255 38 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 15679297 Nonpathogen - hypothetical protein MTH1295 3 None None None 15679005 Common - hypothetical protein MTH987 50 COG1944 COG1944, Uncharacterized conserved protein Function unknown 15678377 Nonpathogen - hypothetical protein MTH349 1 None None None 15679304 Nonpathogen - hypothetical protein MTH1302 32 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 15679378 Common - conserved protein (contains ferredoxin domain) MTH1379 17 COG1036 COG1036, Archaeal flavoproteins Energy production and conversion 15678763 Common - coenzyme F420-reducing hydrogenase, delta subunit homolog MTH737 63 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 15678481 Common - hypothetical protein MTH453 52 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15679068 Common rps12P 30S ribosomal protein S12P MTH1055 231 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 15679530 Common - aryldialkylphosphatase related protein MTH1534 119 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 15678334 Nonpathogen - hypothetical protein MTH306 7 COG1630 COG1630, Uncharacterized protein conserved in archaea Function unknown 15678184 Common - rubredoxin MTH156 123 COG1773 COG1773, Rubredoxin Energy production and conversion 15678629 Nonpathogen - conserved protein (contains ferredoxin domain) MTH601 9 COG1810 COG1810, Uncharacterized protein conserved in archaea Function unknown 15678217 Nonpathogen - hypothetical protein MTH189 1 None None None 15678654 Nonpathogen - hypothetical protein MTH626 2 COG3874 COG3874, Uncharacterized conserved protein Function unknown 15678930 Nonpathogen - hypothetical protein MTH910 1 None None None 15678508 Nonpathogen - hypothetical protein MTH480 1 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 15679091 Common - hypothetical protein MTH1080 34 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15678131 Common - water channel protein MTH103 129 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 15678793 Nonpathogen - hypothetical protein MTH768 4 None None None 15679508 Common - arsenical pump-driving ATPase MTH1511 91 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 15678660 Nonpathogen - hypothetical protein MTH632 1 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15679621 Common - phosphoserine phosphatase MTH1626 200 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15678558 Common - UDP-N-acetylmuramyl tripeptide synthetase related protein MTH530 186 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15679820 Common - quinolinate phosphoribosyltransferase MTH1832 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 15679538 Common - hypothetical protein MTH1542 78 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 15679680 Common - hypothetical protein MTH1686 38 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 15678501 Common - hypothetical protein MTH473 99 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 15678916 Nonpathogen - hypothetical protein MTH896 1 None None None 15679446 Common - dihydroxy-acid dehydratase MTH1449 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15678372 Common - UDP-galactopyranose mutase MTH344 53 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 15679064 Common - DNA-directed RNA polymerase subunit alpha MTH1051 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15678384 Common - sensory transduction histidine kinase MTH356 106 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15679808 Common - homoserine O-acetyltransferase MTH1820 122 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 15678529 Common - 5-methylcytosine-specific restriction enzyme McrB related protein MTH501 44 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 15679165 Common - hypothetical protein MTH1154 75 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15679046 Nonpathogen - hypothetical protein MTH1028 6 COG1627 COG1627, Uncharacterized protein conserved in archaea Function unknown 15678610 Nonpathogen - hypothetical protein MTH582 3 None None None 15678831 Common moaC putative molybdenum cofactor biosynthesis protein C MTH809 196 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15678402 Common - dolichyl-phosphate mannose synthase related protein MTH374 212 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15678522 Common - thermonuclease precursor MTH494 56 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 15679427 Common - bacitracin resistance protein MTH1428 192 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 15679792 Nonpathogen - hypothetical protein MTH1804 3 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 15679884 Common - hypothetical protein MTH1902 109 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 15678498 Nonpathogen - hypothetical protein MTH470 1 None None None 15679720 Common - phosphate-binding protein PstS homolog MTH1728 202 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 15679541 Nonpathogen - hypothetical protein MTH1545 6 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 15679368 Common - molybdenum cofactor biosynthesis MoeA MTH1369 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 15679496 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase MTH1499 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 15678607 Common - fructose-bisphosphate aldolase MTH579 94 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 15678146 Nonpathogen - hypothetical protein MTH118 1 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 15679247 Nonpathogen - hypothetical protein MTH1236 5 None None None 15679866 Common - heterodisulfide reductase, subunit C MTH1878 40 COG1150 HdrC, Heterodisulfide reductase, subunit C Energy production and conversion 15679126 Common - fumarate hydratase, class I MTH1115 60 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 15679842 Common - hypothetical protein MTH1854 38 COG4747 COG4747, ACT domain-containing protein General function prediction only 15678619 Nonpathogen - hypothetical protein MTH591 3 None None None 15678851 Common - molybdenum cofactor biosynthesis MoaA homolog MTH831 188 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 15678419 Nonpathogen - NADH dehydrogenase I, subunit N related protein MTH391 8 COG4078 COG4078, Predicted membrane protein Function unknown 15678265 Common - magnesium chelatase subunit MTH237 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15679347 Common - precorrin-2 methyltransferase MTH1348 139 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 15678939 Common - molybdenum formylmethanofuran dehydrogenase, subunit B MTH919 109 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 15679280 Nonpathogen - hypothetical protein MTH1271 1 None None None 15679570 Common - inosine-5'-monophosphate dehydrogenase related protein X MTH1575 170 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 15678102 Nonpathogen - hypothetical protein MTH74 1 None None None 15678877 Common - hypothetical protein MTH857 78 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 15678109 Nonpathogen - hypothetical protein MTH81 1 None None None 15678646 Common - O6-methylguanidine-DNA methyltransferase MTH618 193 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 15679319 Nonpathogen - hypothetical protein MTH1319 34 COG1736 DPH2, Diphthamide synthase subunit DPH2 Translation, ribosomal structure and biogenesis 15679708 Common - formate hydrogenlyase, iron-sulfur subunit 2 MTH1714 157 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15678090 Nonpathogen - hypothetical protein MTH61 1 None None None 15678872 Nonpathogen - hypothetical protein MTH852 3 COG3608 COG3608, Predicted deacylase General function prediction only 15678238 Common - hypothetical protein MTH210 29 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 15679578 Nonpathogen - hypothetical protein MTH1583 3 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15678187 Common - alkyl hydroperoxide reductase MTH159 215 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15678766 Common - hypothetical protein MTH740 120 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 15678804 Common - hypothetical protein MTH779 27 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 15678441 Common - hypothetical protein MTH413 19 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 15679179 Nonpathogen - methyl coenzyme M reductase I, beta subunit MTH1168 14 COG4054 McrB, Methyl coenzyme M reductase, beta subunit Coenzyme metabolism 15678398 Common - LPS biosynthesis RfbU related protein MTH370 206 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15678879 Common - heat shock protein, class I MTH859 170 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 15678048 Nonpathogen rps14P 30S ribosomal protein S14P MTH17 33 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 15678826 Nonpathogen - chorismate mutase MTH804 6 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 15678186 Common - ferritin like protein (RsgA) MTH158 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 15678542 Common - cobalamin biosynthesis protein N MTH514 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15679492 Common - alanine dehydrogenase MTH1495 99 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 15678036 Common rpl2p 50S ribosomal protein L2P MTH5 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 15679888 Nonpathogen - oligosaccharyl transferase STT3 subunit related protein MTH1906 5 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15678722 Common - hypothetical protein MTH695 192 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15679397 Common - hypothetical protein MTH1398 64 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 15678685 Common - hypothetical protein MTH658 30 COG0824 FcbC, Predicted thioesterase General function prediction only 15678870 Common - aspartate carbamoyltransferase regulatory subunit MTH850 65 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 15678306 Nonpathogen - ferredoxin MTH278 28 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15678757 Nonpathogen - hypothetical protein MTH730 11 COG1844 COG1844, Uncharacterized protein conserved in archaea Function unknown 15679757 Nonpathogen - translation initiation factor IF-2 subunit beta MTH1769 34 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 15678560 Common - UDP-N-acetylmuramyl tripeptide synthetase related protein MTH532 200 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15678350 Nonpathogen - hypothetical protein MTH322 1 None None None 15678099 Nonpathogen - hypothetical protein MTH71 1 None None None 15678671 Common - hypothetical protein MTH644 207 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 15679783 Common - transcriptional regulator MTH1795 153 COG0640 ArsR, Predicted transcriptional regulators Transcription 15678816 Common - chaperonin MTH794 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15679724 Common - phosphate transport system regulator MTH1732 173 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 15678312 Common - ATP-dependent Clp protease regulatory subunit MTH284 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15678994 Common - pyruvate formate-lyase activating enzyme related protein MTH976 77 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15678455 Nonpathogen - hypothetical protein MTH427 1 None None None 15678733 Common - glutamyl-tRNA(Gln) amidotransferase subunit D MTH706 136 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 15679414 Common - ATP-dependent RNA helicase, eIF-4A family MTH1415 63 COG1111 MPH1, ERCC4-like helicases DNA replication, recombination, and repair 15679221 Common - mrr restriction system related protein MTH1210 32 COG1715 Mrr, Restriction endonuclease Defense mechanisms 15678231 Common - ATP-dependent RNA helicase, eIF-4A family MTH203 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15678721 Nonpathogen - hypothetical protein MTH694 1 None None None 15678973 Common - V-type ATP synthase subunit A MTH955 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 15679623 Nonpathogen - hypothetical protein MTH1628 1 None None None 15679294 Common dnaK molecular chaperone DnaK MTH1290 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15678600 Common - polysaccharide biosynthesis protein MTH572 15 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 15679735 Nonpathogen - hypothetical protein MTH1743 1 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 15679113 Nonpathogen - hypothetical protein MTH1102 1 None None None 15678556 Common - hypothetical protein MTH528 38 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 15678914 Common - hypothetical protein MTH894 102 COG0701 COG0701, Predicted permeases General function prediction only 15679139 Nonpathogen - hypothetical protein MTH1128 3 COG1532 COG1532, Predicted RNA-binding protein General function prediction only 15679873 Common - sodium-dependent phosphate transporter MTH1885 170 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 15678519 Common - hypothetical protein MTH491 25 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 15678626 Nonpathogen - hypothetical protein MTH598 2 COG4052 COG4052, Uncharacterized protein related to methyl coenzyme M reductase subunit C General function prediction only 15678293 Nonpathogen - DNA-dependent RNA polymerase, subunit E'' MTH265 29 COG2093 COG2093, DNA-directed RNA polymerase, subunit E'' Transcription 15679897 Common - RNA 3'-terminal-phosphate cyclase MTH1915 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 15679199 Common - pleiotropic regulatory protein DegT MTH1188 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 15679640 Common - ABC transporter MTH1645 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 15678782 Common - rubredoxin oxidoreductase MTH757 30 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 15679388 Common - nifS protein MTH1389 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15679830 Common - hypothetical protein MTH1842 47 COG1099 COG1099, Predicted metal-dependent hydrolases with the TIM-barrel fold General function prediction only 15678638 Common egsA NAD(P)-dependent glycerol-1-phosphate dehydrogenase MTH610 61 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 15678578 Common - DNA-dependent DNA polymerase family X MTH550 70 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 15679693 Nonpathogen ef1B elongation factor 1-beta MTH1699 31 COG2092 EFB1, Translation elongation factor EF-1beta Translation, ribosomal structure and biogenesis 15678483 Nonpathogen - hypothetical protein MTH455 2 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15678691 Common - nitrogen regulatory protein P-II MTH664 186 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15679839 Nonpathogen - hypothetical protein MTH1851 1 None None None 15679473 Common - tryptophan synthase subunit beta MTH1476 225 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 15678275 Common - hypothetical protein MTH247 43 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 15679612 Nonpathogen - hypothetical protein MTH1617 8 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 15679637 Nonpathogen - cell division protein MTH1642 34 COG1537 PelA, Predicted RNA-binding proteins General function prediction only 15679172 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit C MTH1161 14 COG4061 MtrC, Tetrahydromethanopterin S-methyltransferase, subunit C Coenzyme metabolism 15679631 Common - S-adenosyl-L-homocysteine hydrolase MTH1636 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 15679469 Common - O-antigen transporter homolog MTH1472 16 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15679394 Common - pyruvate formate-lyase activating enzyme related protein MTH1395 111 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15678053 Common rpl18p 50S ribosomal protein L18P MTH22 50 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 15678535 Common - hypothetical protein MTH507 56 COG0393 COG0393, Uncharacterized conserved protein Function unknown 15678255 Common cbiC precorrin-8X methylmutase MTH227 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 15679193 Common - hypothetical protein MTH1182 49 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 15679526 Common - hypothetical protein MTH1530 38 COG1786 COG1786, Uncharacterized conserved protein Function unknown 15679285 Nonpathogen - hypothetical protein MTH1281 4 COG1531 COG1531, Uncharacterized protein conserved in archaea Function unknown 15678687 Nonpathogen - hypothetical protein MTH660 1 None None None 15678738 Common - methionine sulfoxide reductase B MTH711 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15678169 Common - hypothetical protein MTH141 26 COG1891 COG1891, Uncharacterized protein conserved in archaea Function unknown 15679147 Nonpathogen - methyl viologen-reducing hydrogenase, delta subunit MTH1136 32 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 15678162 Nonpathogen - riboflavin synthase MTH134 22 COG1731 COG1731, Archaeal riboflavin synthase Coenzyme metabolism 15679207 Common - hypothetical protein MTH1196 70 COG1469 COG1469, Uncharacterized conserved protein Function unknown 15679554 Common - tungsten formylmethanofuran dehydrogenase, subunit C MTH1558 62 COG2218 FwdC, Formylmethanofuran dehydrogenase subunit C Energy production and conversion 15678887 Common - hypothetical protein MTH867 33 COG1915 COG1915, Uncharacterized conserved protein Function unknown 15679036 Common - hypothetical protein MTH1018 69 COG0391 COG0391, Uncharacterized conserved protein Function unknown 15679747 Common - mannose-1-phosphate guanyltransferase MTH1759 240 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 15678064 Common rps13p 30S ribosomal protein S13P MTH34 247 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 15679077 Nonpathogen - hypothetical protein MTH1066 4 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 15679310 Nonpathogen rpl44e 50S ribosomal protein L44e MTH1310 33 COG1631 RPL42A, Ribosomal protein L44E Translation, ribosomal structure and biogenesis 15679549 Common - tungsten formylmethanofuran dehydrogenase, subunit H MTH1553 40 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 15679518 Common - sugar fermentation stimulation protein MTH1521 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 15679331 Nonpathogen - hypothetical protein MTH1331 1 None None None 15678648 Common - Mg2+ transporter MTH620 152 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 15678680 Nonpathogen - hypothetical protein MTH653 3 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15678998 Common - hypothetical protein MTH980 69 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 15678226 Common - hypothetical protein MTH198 17 COG3369 COG3369, Uncharacterized conserved protein Function unknown 15679445 Common - signal peptidase MTH1448 24 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15679608 Nonpathogen rpl39e 50S ribosomal protein L39e MTH1613 31 COG2167 RPL39, Ribosomal protein L39E Translation, ribosomal structure and biogenesis 15679684 Nonpathogen - hypothetical protein MTH1690 5 COG1849 COG1849, Uncharacterized protein conserved in archaea Function unknown 15678964 Nonpathogen - hypothetical protein MTH944 3 None None None 15679132 Nonpathogen - hypothetical protein MTH1121 4 None None None 15678317 Nonpathogen - hypothetical protein MTH289 1 None None None 15678728 Common - acetyl-CoA synthetase related protein MTH701 213 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15679711 Nonpathogen - hypothetical protein MTH1717 5 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 15679022 Nonpathogen - translation initiation factor IF-1A MTH1004 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 15678701 Nonpathogen - hypothetical protein MTH674 8 COG5643 COG5643, Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E General function prediction only 15678119 Nonpathogen - hypothetical protein MTH91 1 None None None 15679151 Common - formate dehydrogenase, alpha subunit related protein FlpC MTH1140 47 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15679794 Common - phycocyanin alpha phycocyanobilin lyase CpcE MTH1806 54 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15678464 Nonpathogen - hypothetical protein MTH436 1 None None None 15678667 Nonpathogen - hypothetical protein MTH640 1 None None None 15678268 Common - replication factor C large subunit MTH240 237 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 15678221 Common - coenzyme F420-reducing hydrogenase, beta subunit homolog MTH193 30 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 15679161 Common - ABC transporter subunit Ycf24 MTH1150 188 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 15679101 Nonpathogen - hypothetical protein MTH1090 1 None None None 15679815 Common - quinolinate synthetase MTH1827 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 15679159 Nonpathogen - hypothetical protein MTH1148 7 COG4016 COG4016, Uncharacterized protein conserved in archaea Function unknown 15678966 Nonpathogen - hypothetical protein MTH948 1 None None None 15679854 Nonpathogen - hypothetical protein MTH1866 14 COG4029 COG4029, Uncharacterized protein conserved in archaea Function unknown 15679168 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit G MTH1157 2 COG4064 MtrG, Tetrahydromethanopterin S-methyltransferase, subunit G Coenzyme metabolism 15679371 Nonpathogen - hypothetical protein MTH1372 1 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 15679840 Common - indolepyruvate oxidoreductase, alpha subunit MTH1852 115 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 15679408 Common - cobalamin biosynthesis protein B MTH1409 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 15679528 Nonpathogen - hypothetical protein MTH1532 1 None None None 15679774 Nonpathogen - hypothetical protein MTH1786 3 COG4001 COG4001, Predicted metal-binding protein General function prediction only 15678656 Common - hypothetical protein MTH628 21 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 15678784 Nonpathogen - hypothetical protein MTH759 2 None None None 15678745 Nonpathogen - hypothetical protein MTH718 15 COG1602 COG1602, Uncharacterized conserved protein Function unknown 15678446 Common - cofactor-independent phosphoglycerate mutase MTH418 57 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 15678244 Common - acetyl-CoA synthetase MTH216 51 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15678905 Nonpathogen tfb transcription initiation factor IIB MTH885 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 15679007 Common - hypothetical protein MTH989 23 COG3482 COG3482, Uncharacterized conserved protein Function unknown 15679846 Common - phage infection protein homolog MTH1858 39 COG1511 COG1511, Predicted membrane protein Function unknown 15678989 Nonpathogen - hypothetical protein MTH971 22 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 15679258 Common - putative monovalent cation/H+ antiporter subunit C MTH1247 38 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 15678379 Common - magnesium chelatase subunit MTH351 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15678159 Common - cobalt transport protein CbiN MTH131 40 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 15679586 Common - cofactor-independent phosphoglycerate mutase MTH1591 52 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 15678853 Nonpathogen - hypothetical protein MTH833 3 None None None 15679215 Common - phosphoribosylaminoimidazole synthetase MTH1204 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 15679594 Nonpathogen cdc6 cell division control protein 6 MTH1599 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 15678802 Nonpathogen - hypothetical protein MTH777 10 COG4081 COG4081, Uncharacterized protein conserved in archaea Function unknown 15678982 Common - hypothetical protein MTH964 10 None None None 15679054 Common - succinyl-CoA synthetase, beta subunit MTH1036 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 15679798 Common - hypothetical protein MTH1810 27 COG2324 COG2324, Predicted membrane protein Function unknown 15678714 Nonpathogen - hypothetical protein MTH687 11 COG1369 POP5, RNase P/RNase MRP subunit POP5 Translation, ribosomal structure and biogenesis 15679345 Nonpathogen - hypothetical protein MTH1346 8 COG5643 COG5643, Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E General function prediction only 15678636 Common - ribose 5-phosphate isomerase MTH608 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 15679478 Common - 2-isopropylmalate synthase MTH1481 225 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15678829 Common - thioredoxin MTH807 23 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 15679543 Common - nitrate assimilation protein, narQ MTH1547 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 15679236 Common - inosine-5'-monophosphate dehydrogenase related protein IV MTH1225 129 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 15679140 Nonpathogen - methyl coenzyme M reductase II, alpha subunit MTH1129 14 COG4058 McrA, Methyl coenzyme M reductase, alpha subunit Coenzyme metabolism 15678840 Common - deoxyribose-phosphate aldolase MTH818 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 15679648 Common - hypothetical protein MTH1653 13 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15678985 Nonpathogen - hypothetical protein MTH967 32 COG1395 COG1395, Predicted transcriptional regulator Transcription 15679519 Nonpathogen - nitrogenase alpha chain (NifD) related protein MTH1522 35 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15678706 Nonpathogen - hypothetical protein MTH679 9 COG2892 COG2892, Uncharacterized protein conserved in archaea Function unknown 15678865 Common - hypothetical protein MTH845 38 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 15678152 Common - hypothetical protein MTH124 95 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 15679183 Common - possible cation transporter MTH1172 200 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 15678422 Nonpathogen - hypothetical protein MTH394 1 None None None 15678598 Nonpathogen - hypothetical protein MTH570 4 None None None 15679315 Common - mutator MutT protein MTH1315 181 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15679822 Nonpathogen - hypothetical protein MTH1834 29 COG1779 COG1779, C4-type Zn-finger protein General function prediction only 15679149 Nonpathogen - methyl viologen-reducing hydrogenase, delta subunit homolog FlpD MTH1138 32 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 15679481 Nonpathogen - hypothetical protein MTH1484 7 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 15679103 Common - hypothetical protein MTH1092 191 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 15678164 Common - dolichyl-phosphate mannose synthase MTH136 204 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15678549 Nonpathogen - hypothetical protein MTH521 2 None None None 15679490 Common - cation transporting P-type ATPase related protein MTH1493 110 COG4087 COG4087, Soluble P-type ATPase General function prediction only 15679670 Common - cell division protein FtsZ MTH1676 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 161484927 Common - bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase MTH1474 63 COG1795 COG1795, Uncharacterized conserved protein Function unknown 15679459 Nonpathogen - hypothetical protein MTH1462 3 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15679270 Common - tetrahydromethanopterin formyltransferase MTH1259 24 COG2037 Ftr, Formylmethanofuran:tetrahydromethanopterin formyltransferase Energy production and conversion 15679335 Common - diaminopimelate decarboxylase MTH1335 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 15678612 Nonpathogen - tRNA CCA-pyrophosphorylase MTH584 34 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 15679044 Common - phosphatidylserine decarboxylase MTH1026 98 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 15678943 Nonpathogen - hypothetical protein MTH923 3 None None None 15679437 Nonpathogen - hypothetical protein MTH1440 1 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 15678526 Common - hypothetical protein MTH498 22 None None None 15679651 Common - anthranilate synthase component II MTH1656 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 15678256 Common - glutamate-1-semialdehyde aminotransferase MTH228 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 15679806 Nonpathogen - hypothetical protein MTH1818 1 None None None 15679803 Common - hypothetical protein MTH1815 23 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 15678328 Nonpathogen - hypothetical protein MTH300 1 None None None 15678833 Nonpathogen - hypothetical protein MTH811 12 COG4066 COG4066, Uncharacterized protein conserved in archaea Function unknown 15678341 Common - transcriptional regulator MTH313 105 COG1846 MarR, Transcriptional regulators Transcription 15678348 Nonpathogen - hypothetical protein MTH320 1 None None None 15679098 Common - hypothetical protein MTH1087 6 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15678520 Common - ATP-dependent RNA helicase, eIF-4A family MTH492 172 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 15678609 Nonpathogen - hypothetical protein MTH581 3 None None None 15679218 Common - phosphonopyruvate decarboxylase related protein MTH1207 42 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15678210 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein MTH182 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 15678148 Common - NADPH-oxidoreductase MTH120 152 COG0778 NfnB, Nitroreductase Energy production and conversion 15679364 Common - hypothetical protein MTH1365 16 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15679685 Common - hypothetical protein MTH1691 51 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15678996 Common - NADP-dependent glyceraldehyde-3-phosphate dehydrogenase MTH978 225 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15679011 Common - hypothetical protein MTH993 157 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15678400 Nonpathogen - hypothetical protein MTH372 2 None None None 15678075 Common - mevalonate kinase MTH46 52 COG1577 ERG12, Mevalonate kinase Lipid metabolism 15679000 Nonpathogen - hypothetical protein MTH982 5 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15678285 Nonpathogen - 50S ribosomal protein L24e MTH257 32 COG2075 RPL24A, Ribosomal protein L24E Translation, ribosomal structure and biogenesis 15678219 Common - glutamine PRPP amidotransferase MTH191 237 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 15678209 Nonpathogen - hypothetical protein MTH181 1 None None None 15679223 Common - dihydroorotate dehydrogenase electron transfer subunit MTH1212 94 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 15678765 Common - nickel responsive regulator MTH739 65 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 15678841 Nonpathogen - hypothetical protein MTH819 10 COG2164 COG2164, Uncharacterized conserved protein Function unknown 15679366 Nonpathogen - hypothetical protein MTH1367 1 None None None 15679197 Common - hypothetical protein MTH1186 166 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15679849 Common - molybdenum cofactor biosynthesis MoaB MTH1861 190 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 15679128 Nonpathogen - phosphoenolpyruvate synthase MTH1117 11 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15678412 Nonpathogen - hypothetical protein MTH384 3 COG4042 COG4042, Predicted membrane protein Function unknown 15678321 Nonpathogen - hypothetical protein MTH293 6 None None None 15679171 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit B MTH1160 12 COG4062 MtrB, Tetrahydromethanopterin S-methyltransferase, subunit B Coenzyme metabolism 15678365 Nonpathogen - hypothetical protein MTH337 3 None None None 15678932 Common - hypothetical protein MTH912 22 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 15678586 Nonpathogen - hypothetical protein MTH558 9 None None None 15678133 Common - glutamate synthase (NADPH), alpha subunit MTH105 223 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 15679306 Nonpathogen - hypothetical protein MTH1306 24 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 15678471 Common - excinuclease ABC subunit A MTH443 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 15679087 Nonpathogen - hypothetical protein MTH1076 5 None None None 15679240 Common - hypothetical protein MTH1229 16 COG2029 COG2029, Uncharacterized conserved protein Function unknown 15679464 Common - imidazoleglycerol-phosphate dehydratase MTH1467 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 15679536 Nonpathogen - hypothetical protein MTH1540 4 None None None 15678507 Common - hypothetical protein MTH479 61 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 15678191 Nonpathogen - hypothetical protein MTH163 22 COG1497 COG1497, Predicted transcriptional regulator Transcription 15678088 Nonpathogen - hypothetical protein MTH59 1 None None None 15678954 Nonpathogen - hypothetical protein MTH934 1 None None None 15679066 Nonpathogen - 50S ribosomal protein L30e MTH1053 28 COG1911 RPL30, Ribosomal protein L30E Translation, ribosomal structure and biogenesis 15679890 Nonpathogen - hypothetical protein MTH1908 2 None None None 15679660 Common - glutamate synthase (NADPH), alpha subunit related protein MTH1666 208 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 15678359 Common - mannosyltransferase MTH331 173 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15678073 Common rps2P 30S ribosomal protein S2 MTH44 132 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 15678352 Nonpathogen - hypothetical protein MTH324 5 None None None 15679683 Common - hypothetical protein MTH1689 67 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 15679533 Common - adenylosuccinate lyase MTH1537 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 15678331 Common - hypothetical protein MTH303 19 COG2234 Iap, Predicted aminopeptidases General function prediction only 15678093 Nonpathogen - hypothetical protein MTH64 1 None None None 15679256 Nonpathogen - hypothetical protein MTH1245 3 None None None 15679584 Common - glucose-1-phosphate thymidylyltransferase homolog MTH1589 242 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 15678836 Nonpathogen - hypothetical protein MTH814 7 COG4014 COG4014, Uncharacterized protein conserved in archaea Function unknown 15678665 Nonpathogen - hypothetical protein MTH637 16 COG1872 COG1872, Uncharacterized conserved protein Function unknown 15678207 Nonpathogen - hypothetical protein MTH179 7 None None None 15678554 Common - hypothetical protein MTH526 31 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 15678179 Common - methyl coenzyme M reductase system, component A2 homolog MTH151 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 15679503 Common hisG ATP phosphoribosyltransferase MTH1506 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 15679308 Common - translation initiation factor IF-2 subunit alpha MTH1308 143 COG1093 SUI2, Translation initiation factor 2, alpha subunit (eIF-2alpha) Translation, ribosomal structure and biogenesis 15678200 Common - hypothetical protein MTH172 116 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15679029 Common - ATP-dependent 26S protease regulatory subunit 8 MTH1011 249 COG1223 COG1223, Predicted ATPase (AAA+ superfamily) General function prediction only 15678944 Common - molybdate-binding periplasmic protein MTH924 130 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 15678563 Common - methionine sulfoxide reductase A MTH535 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15679892 Common - fumarate hydratase, class I related protein MTH1910 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 15679619 Common - DNA topoisomerase I MTH1624 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15679061 Nonpathogen rpoH DNA-directed RNA polymerase subunit H MTH1048 33 COG2012 RPB5, DNA-directed RNA polymerase, subunit H, RpoH/RPB5 Transcription 15678650 Common - thiosulfate sulfurtransferase MTH622 140 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15678103 Common - surface protease related protein MTH75 17 COG3291 COG3291, FOG: PKD repeat General function prediction only 15678669 Nonpathogen - hypothetical protein MTH642 1 None None None 15679219 Common - DNA-dependent DNA polymerase family B (PolB1) MTH1208 67 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 15678262 Common - gamma-carboxymuconolactone decarboxylase MTH234 77 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 15678761 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase MTH735 218 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15679467 Nonpathogen - molybdenum transport protein ModA related protein MTH1470 3 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 15678842 Common - hypothetical protein MTH820 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 15678382 Common - hypothetical protein MTH354 4 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 15678280 Nonpathogen - hypothetical protein MTH252 6 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 15679837 Common - hypothetical protein MTH1849 153 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 15679442 Common - glycinamide ribonucleotide synthetase MTH1445 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 15679862 Nonpathogen - diphthine synthase MTH1874 34 COG1798 DPH5, Diphthamide biosynthesis methyltransferase Translation, ribosomal structure and biogenesis 15678495 Nonpathogen - hypothetical protein MTH467 1 None None None 15679194 Common - pheromone shutdown protein TraB MTH1183 39 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 15679042 Common - rod shape-determining protein MTH1024 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 15679825 Common - hypothetical protein MTH1837 34 COG3367 COG3367, Uncharacterized conserved protein Function unknown 15678189 Common - coenzyme F390 synthetase III MTH161 118 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 15679801 Common - serine protease HtrA MTH1813 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15678923 Common - photoreactivation-associated protein MTH903 70 COG3272 COG3272, Uncharacterized conserved protein Function unknown 15678343 Common - hypothetical protein MTH315 4 None None None 15679055 Nonpathogen - hypothetical protein MTH1037 4 None None None 15678253 Common hisD histidinol dehydrogenase MTH225 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 15679327 Nonpathogen - hypothetical protein MTH1327 2 None None None 15679344 Common - hypothetical protein MTH1345 39 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 15678475 Common - sensory transduction regulatory protein MTH447 221 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 15678180 Common - hypothetical protein MTH152 74 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 15678797 Common - conserved protein (contains ferredoxin domain) MTH772 51 COG2006 COG2006, Uncharacterized conserved protein Function unknown 15678406 Common - hypothetical protein MTH378 42 COG0392 COG0392, Predicted integral membrane protein Function unknown 15679804 Common - hypothetical protein MTH1816 39 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 15679228 Nonpathogen nusA transcription elongation factor NusA-like protein MTH1217 12 COG0195 NusA, Transcription elongation factor Transcription 15678576 Common - sensory transduction regulatory protein MTH548 218 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 15679283 Common - hypothetical protein MTH1279 12 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15679435 Nonpathogen - hypothetical protein MTH1438 13 COG1777 COG1777, Predicted transcriptional regulators Transcription 15679330 Common - hypothetical protein MTH1330 43 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15679881 Nonpathogen - hypothetical protein MTH1899 1 None None None 15679671 Nonpathogen secE preprotein translocase subunit SecE MTH1677 2 COG2443 Sss1, Preprotein translocase subunit Sss1 Intracellular trafficking and secretion 15678961 Common - type I restriction modification system, subunit S MTH941 129 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 15679545 Common - NADP-reducing hydrogenase, subunit C MTH1549 183 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 15679406 Nonpathogen - hypothetical protein MTH1407 28 COG1698 COG1698, Uncharacterized protein conserved in archaea Function unknown 15678855 Common - hypothetical protein MTH835 23 COG1821 COG1821, Predicted ATP-utilizing enzyme (ATP-grasp superfamily) General function prediction only 15678726 Common - hypothetical protein MTH699 33 COG1839 COG1839, Uncharacterized conserved protein Function unknown 15679001 Nonpathogen - hypothetical protein MTH983 1 None None None 15679453 Common - chromosome partitioning protein Soj MTH1456 207 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15679231 Common - chorismate mutase MTH1220 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 15679474 Nonpathogen - hypothetical protein MTH1477 12 COG4012 COG4012, Uncharacterized protein conserved in archaea Function unknown 15678310 Common - hypothetical protein MTH282 3 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15679081 Common - hypothetical protein MTH1070 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 15678423 Nonpathogen - hypothetical protein MTH395 5 COG4035 COG4035, Predicted membrane protein Function unknown 15678599 Common - nitrogenase reductase related protein MTH571 42 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 15679307 Nonpathogen - hypothetical protein MTH1307 22 COG2260 COG2260, Predicted Zn-ribbon RNA-binding protein Translation, ribosomal structure and biogenesis 15678849 Common - 3-isopropylmalate dehydratase, LeuD subunit MTH829 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 15678431 Common - tetrahydromethanopterin formyltransferase MTH403 24 COG2037 Ftr, Formylmethanofuran:tetrahydromethanopterin formyltransferase Energy production and conversion 15678614 Nonpathogen - DNA primase large subunit MTH586 5 COG2219 PRI2, Eukaryotic-type DNA primase, large subunit DNA replication, recombination, and repair 15679092 Nonpathogen - hypothetical protein MTH1081 3 COG1421 COG1421, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 15679185 Common - cell division inhibitor related protein MTH1174 32 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15679008 Common - hypothetical protein MTH990 63 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 15679780 Common - dTDP-4-dehydrorhamnose reductase MTH1792 189 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 15678794 Nonpathogen - hypothetical protein MTH769 4 None None None 15678295 Nonpathogen rps24e 30S ribosomal protein S24e MTH267 17 COG2004 RPS24A, Ribosomal protein S24E Translation, ribosomal structure and biogenesis 15678539 Common - DNA helicase II MTH511 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15679564 Nonpathogen - hypothetical protein MTH1568 3 COG4013 COG4013, Uncharacterized protein conserved in archaea Function unknown 15678983 Common - hypothetical protein MTH965 61 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 15678436 Nonpathogen - hypothetical protein MTH408 13 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 15679109 Common ubiA prenyltransferase MTH1098 65 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15679187 Common - nucleotide-binding protein (putative ATPase) MTH1176 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15678046 Nonpathogen - 30S ribosomal protein S4e MTH15 34 COG1471 RPS4A, Ribosomal protein S4E Translation, ribosomal structure and biogenesis 15678147 Common - ATP phosphoribosyltransferase related protein MTH119 122 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 15679614 Nonpathogen - conserved protein (adenylate kinase related) MTH1619 31 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 15679829 Common - ribokinase MTH1841 143 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15678768 Common pheS phenylalanyl-tRNA synthetase subunit alpha MTH742 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 15679812 Nonpathogen - hypothetical protein MTH1824 3 COG1633 COG1633, Uncharacterized conserved protein Function unknown 15678603 Nonpathogen - hypothetical protein MTH575 1 None None None 15678828 Common - protease IV MTH806 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15679317 Nonpathogen - DNA-dependent RNA polymerase, subunit L MTH1317 14 COG1761 RPB11, DNA-directed RNA polymerase, subunit L Transcription 15679841 Common - indolepyruvate oxidoreductase subunit B MTH1853 98 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 15678140 Nonpathogen - hypothetical protein MTH112 1 COG1814 COG1814, Uncharacterized membrane protein Function unknown 15678864 Common - autotrophic growth protein MTH844 123 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 15679847 Nonpathogen - hypothetical protein MTH1859 5 COG1873 COG1873, Uncharacterized conserved protein Function unknown 15678643 Common - adenylosuccinate synthetase MTH615 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 15679167 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit H MTH1156 17 COG1962 MtrH, Tetrahydromethanopterin S-methyltransferase, subunit H Coenzyme metabolism 15678907 Nonpathogen - hypothetical protein MTH887 17 COG0392 COG0392, Predicted integral membrane protein Function unknown 15679773 Common - coenzyme PQQ synthesis protein MTH1785 136 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 15678514 Nonpathogen - hypothetical protein MTH486 1 None None None 15679292 Nonpathogen - hypothetical protein MTH1288 18 COG1777 COG1777, Predicted transcriptional regulators Transcription 15679170 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit A MTH1159 17 COG4063 MtrA, Tetrahydromethanopterin S-methyltransferase, subunit A Coenzyme metabolism 15678847 Common - L-isoaspartyl protein carboxyl methyltransferase MTH827 166 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 15679246 Nonpathogen - hypothetical protein MTH1235 15 COG1707 COG1707, ACT domain-containing protein General function prediction only 15679701 Common - cobalt transport protein CbiM MTH1707 80 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 15679152 Nonpathogen - conserved protein (FlpE) MTH1141 2 None None None 15679234 Common - inosine-5'-monophosphate dehydrogenase related protein II MTH1223 169 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 15678376 Common - rhamnosyl transferase MTH348 64 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15679374 Common ileS isoleucyl-tRNA synthetase MTH1375 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678172 Nonpathogen - hypothetical protein MTH144 2 None None None 15678199 Common - glutamine-fructose-6-phosphate transaminase MTH171 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 15679712 Common - bacteriochlorophyll synthase 43 kDa subunit MTH1718 128 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15678467 Common - recombinase MTH439 65 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 15679796 Common - phytoene synthase MTH1808 105 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 15678625 Nonpathogen - hypothetical protein MTH597 1 None None None 15679323 Nonpathogen - 50S ribosomal protein L21e MTH1323 34 COG2139 RPL21A, Ribosomal protein L21E Translation, ribosomal structure and biogenesis 15679589 Nonpathogen - hypothetical protein MTH1594 2 None None None 15679462 Common - hypothetical protein MTH1465 55 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 15679145 Common - methyl viologen-reducing hydrogenase, alpha subunit MTH1134 102 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 15678329 Nonpathogen - hypothetical protein MTH301 2 None None None 15678112 Nonpathogen - hypothetical protein MTH84 1 None None None 15679198 Nonpathogen - hypothetical protein MTH1187 20 COG0011 COG0011, Uncharacterized conserved protein Function unknown 15679500 Nonpathogen - hypothetical protein MTH1503 4 COG0546 Gph, Predicted phosphatases General function prediction only 15678548 Common - hypothetical protein MTH520 5 None None None 15678315 Common - anaerobic ribonucleoside-triphosphate reductase activating protein MTH287 85 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 15678933 Nonpathogen - hypothetical protein MTH913 6 COG5643 COG5643, Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E General function prediction only 15678505 Common - sulfate transport system ATP-binding MTH477 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 15679024 Nonpathogen - hypothetical protein MTH1006 33 COG1094 COG1094, Predicted RNA-binding protein (contains KH domains) General function prediction only 15678469 Common - excinuclease ABC subunit C MTH441 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15678900 Nonpathogen - hypothetical protein MTH880 5 COG4068 COG4068, Uncharacterized protein containing a Zn-ribbon Function unknown 15679386 Common - 3-isopropylmalate dehydratase, LeuC subunit MTH1387 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 15679778 Common - dTDP-4-dehydrorhamnose 3,5-epimerase MTH1790 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 15678478 Common - LPS biosynthesis RfbU related protein MTH450 232 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15679566 Common - glutamine synthetase MTH1570 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 15678485 Common - sensory transduction regulatory protein MTH457 222 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 15678776 Common - hypothetical protein MTH751 38 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 15679872 Common - hypothetical protein MTH1884 47 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 15679281 Nonpathogen - hypothetical protein MTH1277 1 COG4640 COG4640, Predicted membrane protein Function unknown 15679748 Common - trehalose-6-phosphate phophatase related protein MTH1760 83 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 15678342 Common - hypothetical protein MTH314 96 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15678534 Nonpathogen - hypothetical protein MTH506 3 COG0393 COG0393, Uncharacterized conserved protein Function unknown 15679856 Nonpathogen - hypothetical protein MTH1868 14 COG4050 COG4050, Uncharacterized protein conserved in archaea Function unknown 15679034 Nonpathogen - hypothetical protein MTH1016 17 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15679758 Common - DNA replication initiator (Cdc21/Cdc54) MTH1770 37 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 15678594 Common - 3-dehydroquinate dehydratase MTH566 58 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 15678218 Common - hypothetical protein MTH190 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 15678224 Common - hypothetical protein MTH196 35 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 15678678 Nonpathogen - hypothetical protein MTH651 8 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 15678788 Nonpathogen - hypothetical protein MTH763 21 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 15679764 Common - hypothetical protein MTH1776 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 15679789 Common - hypothetical protein MTH1801 15 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15679076 Common - hypothetical protein MTH1065 43 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15678163 Common - hypothetical protein MTH135 90 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15678645 Nonpathogen - hypothetical protein MTH617 1 None None None 15679395 Common - thiamine monphosphate kinase MTH1396 223 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 15678051 Nonpathogen rpl32e 50S ribosomal protein L32e MTH20 34 COG1717 RPL32, Ribosomal protein L32E Translation, ribosomal structure and biogenesis 15678581 Nonpathogen rpl40e 50S ribosomal protein L40e MTH553 23 COG1552 RPL40A, Ribosomal protein L40E Translation, ribosomal structure and biogenesis 15679383 Nonpathogen - replication factor A related protein MTH1384 6 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 15678261 Common - hypothetical protein MTH233 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15679558 Common - nitrogenase GlnBb subunit MTH1562 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 15678157 Common - orotidine 5' monophosphate decarboxylase MTH129 180 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 15678444 Nonpathogen - hypothetical protein MTH416 18 COG2061 COG2061, ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase Amino acid transport and metabolism 15679898 Common - biotin acetyl-CoA carboxylase ligase / biotin operon repressor bifunctional protein MTH1916 232 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 15678142 Common - arylsulfatase regulatory protein MTH114 71 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 15679122 Nonpathogen - hypothetical protein MTH1111 14 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 15678771 Common - unknown (contains ferredoxin domain) MTH745 26 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 15678951 Common - hypothetical protein MTH931 8 COG1846 MarR, Transcriptional regulators Transcription 15679116 Common - hypothetical protein MTH1105 59 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 15679606 Nonpathogen - translation initiation factor IF-6 MTH1611 33 COG1976 TIF6, Translation initiation factor 6 (eIF-6) Translation, ribosomal structure and biogenesis 15678190 Common - hypothetical protein MTH162 38 COG4747 COG4747, ACT domain-containing protein General function prediction only 15678814 Common - hypothetical protein MTH792 169 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 15679493 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A MTH1496 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 15678732 Common - 2-oxoisovalerate oxidoreductase, alpha subunit MTH705 110 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 15678821 Common - aspartate-semialdehyde dehydrogenase MTH799 206 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15679356 Common - hypothetical protein MTH1357 22 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 15679136 Common - fkbp-type peptidyl-prolyl cis-trans isomerase MTH1125 120 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 15678739 Nonpathogen - hypothetical protein MTH712 1 None None None 15679192 Nonpathogen - hypothetical protein MTH1181 3 None None None 15678473 Common - sensory transduction regulatory protein MTH445 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15678673 Common - amidophosphoribosyltransferase MTH646 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 15679071 Common - elongation factor 1-alpha MTH1058 249 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 15679751 Common - collagenase MTH1763 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15679014 Common - carbamoyl-phosphate synthase, large subunit MTH996 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15678958 Nonpathogen - hypothetical protein MTH938 8 COG1504 COG1504, Uncharacterized conserved protein Function unknown 15679667 Common - SN-glycerol-3-phosphate transport ATP-binding protein MTH1673 244 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15678232 Common - hypothetical protein MTH204 32 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 15679851 Nonpathogen - hypothetical protein MTH1863 9 COG4069 COG4069, Uncharacterized protein conserved in archaea Function unknown 15678801 Nonpathogen - hypothetical protein MTH776 6 COG4033 COG4033, Uncharacterized protein conserved in archaea Function unknown 15678037 Common rps19p 30S ribosomal protein S19P MTH6 219 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 15678623 Common - hypothetical protein MTH595 23 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 15679275 Common - TRK system potassium uptake protein TrkH MTH1264 146 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15678921 Common - sensory transduction regulatory protein MTH901 212 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678414 Nonpathogen - hypothetical protein MTH386 7 COG4040 COG4040, Predicted membrane protein Function unknown 15678127 Nonpathogen - hypothetical protein MTH99 1 None None None 15678928 Nonpathogen - hypothetical protein MTH908 1 None None None 15678150 Common - mutator MutT related protein MTH122 137 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15679325 Nonpathogen - hypothetical protein MTH1325 33 COG1491 COG1491, Predicted RNA-binding protein Translation, ribosomal structure and biogenesis 15678647 Common - sensory transduction histidine kinase MTH619 160 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15679486 Common - hypothetical protein MTH1489 27 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 15679571 Common - thiamine biosynthesis protein ThiC MTH1576 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 15679204 Common - transcriptional regulator MTH1193 77 COG1522 Lrp, Transcriptional regulators Transcription 15678875 Common - inosine-5'-monophosphate dehydrogenase related protein VIII MTH855 138 COG1900 COG1900, Uncharacterized conserved protein Function unknown 15679626 Common - 3-isopropylmalate dehydratase, LeuC subunit MTH1631 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 15679521 Common hisH imidazole glycerol phosphate synthase subunit HisH MTH1524 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 15678913 Common - integrase-recombinase protein MTH893 234 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15679252 Common - polyferredoxin MTH1241 127 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 15678353 Common - hypothetical protein MTH325 21 COG1336 COG1336, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15678743 Common - cell surface glycoprotein (s-layer protein) MTH716 54 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 15679644 Common - hydrogenase expression/formation protein HypC MTH1649 89 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15679313 Nonpathogen - hypothetical protein MTH1313 2 None None None 15678971 Common - V-type ATP synthase subunit D MTH953 47 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 15679799 Common - N-carbamoyl-D-amino acid amidohydrolase MTH1811 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15679600 Common - deoxycytidine-triphosphate deaminase related protein MTH1605 66 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 15679579 Common - phosphomannomutase MTH1584 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15678066 Nonpathogen rps11p 30S ribosomal protein S11P MTH36 32 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 15679432 Common - survival protein SurE MTH1435 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 15678058 Common - adenylate kinase MTH27 26 COG2019 AdkA, Archaeal adenylate kinase Nucleotide transport and metabolism 15679225 Nonpathogen - pre-mRNA splicing protein PRP31 MTH1214 34 COG1498 SIK1, Protein implicated in ribosomal biogenesis, Nop56p homolog Translation, ribosomal structure and biogenesis 15679457 Common - cobyrinic acid a,c-diamide synthase MTH1460 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 15679510 Common - cell surface glycoprotein (s-layer protein) related protein MTH1513 45 None None None 15679694 Nonpathogen - hypothetical protein MTH1700 21 COG1784 COG1784, Predicted membrane protein Function unknown 15678287 Common - translation initiation factor IF-2 MTH259 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 15678561 Nonpathogen - hypothetical protein MTH533 1 None None None 15678071 Nonpathogen - DNA-dependent RNA polymerase, subunit K MTH42 28 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 15679173 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit D MTH1162 14 COG4060 MtrD, Tetrahydromethanopterin S-methyltransferase, subunit D Coenzyme metabolism 15678120 Nonpathogen - hypothetical protein MTH92 1 None None None 15678891 Common - bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase MTH871 199 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 15678731 Common - 2-ketoisovalerate ferredoxin reductase MTH704 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15678453 Nonpathogen - hypothetical protein MTH425 1 None None None 15678754 Common - hypothetical protein MTH727 36 COG2122 COG2122, Uncharacterized conserved protein Function unknown 15678395 Common - O-antigen transporter MTH367 44 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15679349 Common - flavoprotein AI MTH1350 79 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15678497 Common - hypothetical protein MTH469 25 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 15678338 Nonpathogen - hypothetical protein MTH310 1 COG1673 COG1673, Uncharacterized protein conserved in archaea Function unknown 15678616 Nonpathogen - hypothetical protein MTH588 7 COG1771 COG1771, Uncharacterized protein conserved in archaea Function unknown 15678934 Nonpathogen - hypothetical protein MTH914 5 COG5643 COG5643, Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E General function prediction only 15679845 Nonpathogen - hypothetical protein MTH1857 4 None None None 15679339 Nonpathogen - hypothetical protein MTH1339 4 None None None 15678380 Common - hypothetical protein MTH352 25 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 15679040 Common - biopolymer transport protein MTH1022 124 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15678416 Nonpathogen - hypothetical protein MTH388 4 COG4038 COG4038, Predicted membrane protein Function unknown 15679827 Nonpathogen - hypothetical protein MTH1839 1 None None None 15678135 Nonpathogen - hypothetical protein MTH107 3 COG1414 IclR, Transcriptional regulator Transcription 15678387 Common - hypothetical protein MTH359 48 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 15678574 Common - cationic amino acid transporter related protein MTH546 191 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 15679180 Nonpathogen - hypothetical protein MTH1169 1 None None None 15679834 Common - glycyl-tRNA synthetase MTH1846 88 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15679049 Nonpathogen - hypothetical protein MTH1031 21 COG2098 COG2098, Uncharacterized protein conserved in archaea Function unknown 15678773 Common - hypothetical protein MTH747 78 COG2013 COG2013, Uncharacterized conserved protein Function unknown 15678524 Common - endonuclease III homolog MTH496 235 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 15678404 Common - hypothetical protein MTH376 78 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15678345 Common - cobalamin biosynthesis protein N MTH317 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15678799 Common thyA thymidylate synthase MTH774 58 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 15679883 Common - hypothetical protein MTH1901 5 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15679673 Common rpl11p 50S ribosomal protein L11P MTH1679 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 15678477 Common - hypothetical protein MTH449 32 COG1415 COG1415, Uncharacterized conserved protein Function unknown 15679809 Nonpathogen - hypothetical protein MTH1821 2 None None None 15679342 Common - 8-oxoguanine DNA glycosylase MTH1342 26 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 15679655 Common trpA tryptophan synthase subunit alpha MTH1660 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 15679301 Common - coenzyme F420-reducing hydrogenase, delta subunit MTH1299 68 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 15678083 Nonpathogen - hypothetical protein MTH54 2 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15679241 Common - hypothetical protein MTH1230 23 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 15678946 Common - tungsten formylmethanofuran dehydrogenase, subunit F homolog MTH926 165 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15678652 Nonpathogen - hypothetical protein MTH624 1 None None None 15679868 Nonpathogen - hypothetical protein MTH1880 6 COG4009 COG4009, Uncharacterized protein conserved in archaea Function unknown 15679505 Common leuS leucyl-tRNA synthetase MTH1508 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678039 Common rps3p 30S ribosomal protein S3P MTH8 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 15678460 Common - hypothetical protein MTH432 51 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 15678289 Common - translation initiation factor IF-2 subunit gamma MTH261 249 COG5257 GCD11, Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) Translation, ribosomal structure and biogenesis 15678552 Nonpathogen - hypothetical protein MTH524 4 None None None 15678213 Common - hypothetical protein MTH185 12 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15679539 Common - thiamine biosynthesis protein ThiC MTH1543 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 15678196 Common - phosphoribosylformylglycinamidine synthase I MTH168 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 15679460 Common - ABC transporter related protein MTH1463 59 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15678605 Nonpathogen - hypothetical protein MTH577 32 COG1829 COG1829, Predicted archaeal kinase (sugar kinase superfamily) General function prediction only 15678130 Nonpathogen - hypothetical protein MTH102 10 COG4855 COG4855, Uncharacterized protein conserved in archaea Function unknown 15679876 Common - aspartate aminotransferase homolog MTH1894 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15679531 Common - heavy-metal transporting CPx-type ATPase MTH1535 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15678061 Common - cytidylate kinase MTH30 34 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 15679063 Common - DNA-directed RNA polymerase subunit B' MTH1050 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 15678545 Nonpathogen - hypothetical protein MTH517 5 COG3355 COG3355, Predicted transcriptional regulator Transcription 15679628 Nonpathogen - flap endonuclease-1 MTH1633 34 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 15678747 Nonpathogen - hypothetical protein MTH720 32 COG1602 COG1602, Uncharacterized conserved protein Function unknown 15679202 Nonpathogen - hypothetical protein MTH1191 3 None None None 15679894 Nonpathogen - hypothetical protein MTH1912 3 None None None 15678324 Nonpathogen - hypothetical protein MTH296 3 None None None 15678641 Common - hypothetical protein MTH613 32 COG1920 COG1920, Uncharacterized conserved protein Function unknown 15678862 Nonpathogen - hypothetical protein MTH842 12 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 15679703 Nonpathogen - acetyl-CoA decarbonylase/synthase complex subunit epsilon MTH1709 11 COG1880 CdhB, CO dehydrogenase/acetyl-CoA synthase epsilon subunit Energy production and conversion 15679661 Nonpathogen - hypothetical protein MTH1667 1 None None None 15679602 Common - sensory transduction regulatory protein MTH1607 219 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 15678204 Common - tRNA-guanine transglycosylase MTH176 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 15678710 Common - exosome complex exonuclease Rrp41 MTH683 233 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 15679425 Common - hypothetical protein MTH1426 40 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 15678044 Common rpl14p 50S ribosomal protein L14P MTH13 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 15678149 Nonpathogen - hypothetical protein MTH121 1 None None None 15679502 Common - N-ethylammeline chlorohydrolase MTH1505 180 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15679592 Common - hypothetical protein MTH1597 119 COG1690 RtcB, Uncharacterized conserved protein Function unknown 15679609 Nonpathogen - hypothetical protein MTH1614 19 COG2117 COG2117, Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 15678704 Nonpathogen - hypothetical protein MTH677 2 None None None 15679003 Common - sensory transduction histidine kinase MTH985 146 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678264 Nonpathogen - hypothetical protein MTH236 4 COG1790 COG1790, Uncharacterized protein conserved in archaea Function unknown 15678589 Nonpathogen - hypothetical protein MTH561 7 COG1814 COG1814, Uncharacterized membrane protein Function unknown 15679254 Common - putative monovalent cation/H+ antiporter subunit B MTH1243 14 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 15679818 Common - hypothetical protein MTH1830 230 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15679265 Common - argininosuccinate synthase MTH1254 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 15679771 Nonpathogen - hypothetical protein MTH1783 1 None None None 15679244 Common - hypothetical protein MTH1233 5 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 15679653 Nonpathogen - 5'-phosphoribosyl anthranilate isomerase MTH1658 7 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 15678182 Nonpathogen - hypothetical protein MTH154 2 None None None 15679376 Common - hypothetical protein MTH1377 18 COG1430 COG1430, Uncharacterized conserved protein Function unknown 15679791 Nonpathogen - hypothetical protein MTH1803 37 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 15679154 Common - biotin synthase MTH1143 33 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15678276 Common - hypothetical protein MTH248 45 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 15678857 Common - UDP-N-acetylglucosamine 2-epimerase MTH837 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 15678808 Common - ribose-phosphate pyrophosphokinase MTH784 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15679730 Common - pyruvate ferredoxin oxidoreductase subunit beta MTH1738 129 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 15678434 Common - hypothetical protein MTH406 61 COG0517 COG0517, FOG: CBS domain General function prediction only 15679238 Common - coenzyme PQQ synthesis protein III MTH1227 170 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 15679901 Nonpathogen - Zn-ribbon RNA-binding protein involved in translation conserved protein MTH1698a 25 COG2888 COG2888, Predicted Zn-ribbon RNA-binding protein with a function in translation Translation, ribosomal structure and biogenesis 15678963 Common - hypothetical protein MTH943 17 COG1892 COG1892, Uncharacterized protein conserved in archaea Function unknown 15678246 Common - chaperonin MTH218 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15679547 Common - molybdopterin-guanine dinucleotide biosynthesis protein B related MTH1551 75 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 15679451 Common - hypothetical protein MTH1454 36 COG1378 COG1378, Predicted transcriptional regulators Transcription 15679885 Common - hypothetical protein MTH1903 81 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 15679102 Nonpathogen - hypothetical protein MTH1091 20 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15679189 Common - hypothetical protein MTH1178 37 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 15679540 Common - ribokinase MTH1544 209 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15679053 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit gamma MTH1035 79 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 15678425 Common - formate hydrogenlyase, subunit 7 MTH397 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 15678368 Common - hypothetical protein MTH340 35 COG2327 WcaK, Uncharacterized conserved protein Function unknown 15678559 Common - UDP-N-acetylmuramyl tripeptide synthetase related protein MTH531 171 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15679120 Common - hypothetical protein MTH1109 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 15679476 Nonpathogen - hypothetical protein MTH1479 12 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 15679688 Common - aspartate aminotransferase MTH1694 233 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15678438 Nonpathogen - hypothetical protein MTH410 1 None None None 15678869 Common secD preprotein translocase subunit SecD MTH849 108 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 15678296 Nonpathogen - 30S ribosomal protein S27ae MTH268 21 COG1998 RPS31, Ribosomal protein S27AE Translation, ribosomal structure and biogenesis 15678237 Common - hypothetical protein MTH209 163 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 15678173 Common - hypothetical protein MTH145 15 None None None 15678981 Common - fumarate hydratase, class I related protein MTH963 70 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15678631 Common - hypothetical protein MTH603 57 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 15678259 Nonpathogen - hypothetical protein MTH231 14 COG4002 COG4002, Predicted phosphotransacetylase General function prediction only 15678487 Common - sensory transduction histidine kinase MTH459 109 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15679512 Common - translation-associated GTPase MTH1515 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 15678924 Common - DNA deoxyribodipyrimidine photolyase (photoreactivation) MTH904 46 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 15678778 Common - hypothetical protein MTH753 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 15678532 Nonpathogen - H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein MTH504 6 COG4007 COG4007, Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase General function prediction only 15679032 Nonpathogen - hypothetical protein MTH1014 14 COG4008 COG4008, Predicted metal-binding transcription factor Transcription 15678222 Common - glutamate synthase (NADPH), alpha subunit MTH194 204 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 15679107 Common - hypothetical protein MTH1096 81 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15679094 Common - hypothetical protein MTH1083 35 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 15678165 Nonpathogen - hypothetical protein MTH137 1 COG2456 COG2456, Uncharacterized conserved protein Function unknown 15678386 Common - gluthatione-regulated K+/H+ antiporter MTH358 211 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15678949 Nonpathogen - hypothetical protein MTH929 1 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15678068 Nonpathogen - 50S ribosomal protein L18e MTH38 34 COG1727 RPL18A, Ribosomal protein L18E Translation, ribosomal structure and biogenesis 15679732 Common - indolepyruvate ferredoxin oxidoreductase MTH1740 72 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 15678812 Common - sodium/dicarboxylate or sulfate cotransporter MTH788 141 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15679766 Nonpathogen - hypothetical protein MTH1778 1 None None None 15678809 Common - ATP-dependent protease LA MTH785 201 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 15679455 Common - hypothetical protein MTH1458 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 15678110 Nonpathogen - hypothetical protein MTH82 1 None None None 15678845 Common - sensory transduction histidine kinase MTH823 167 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678117 Nonpathogen - hypothetical protein MTH89 1 None None None 15678786 Common - hypothetical protein MTH761 113 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15679494 Common - cobyrinic acid a,c-diamide synthase MTH1497 18 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 15679635 Common - prephenate dehydrogenase MTH1640 86 COG4937 COG4937, Predicted regulatory domain of prephenate dehydrogenase Translation, ribosomal structure and biogenesis 15679864 Common - hypothetical protein MTH1876 84 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15678618 Common - N-acetylglucosamine-1-phosphate transferase MTH590 72 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15678696 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase related protein MTH669 169 COG1411 COG1411, Uncharacterized protein related to proFAR isomerase (HisA) General function prediction only 15678823 Common dapA dihydrodipicolinate synthase MTH801 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15678080 Common gltX glutamyl-tRNA synthetase MTH51 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15678298 Nonpathogen - hypothetical protein MTH270 1 None None None 15679039 Nonpathogen - hypothetical protein MTH1021 3 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 15679118 Common - pyruvate carboxylase subunit B MTH1107 196 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 15678737 Common - GMP synthase subunit B MTH710 238 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 15678049 Common rps8p 30S ribosomal protein S8P MTH18 236 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 15678698 Common - hypothetical protein MTH671 21 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15679134 Nonpathogen - hypothetical protein MTH1123 3 None None None 15678620 Nonpathogen - hypothetical protein MTH592 19 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 15678717 Nonpathogen - 50S ribosomal protein L15e MTH690 34 COG1632 RPL15A, Ribosomal protein L15E Translation, ribosomal structure and biogenesis 15678197 Nonpathogen - hypothetical protein MTH169 29 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 15679587 Common - hypothetical protein MTH1592 31 COG1836 COG1836, Predicted membrane protein Function unknown 15678291 Common - inorganic pyrophosphatase MTH263 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 15679675 Nonpathogen rplP0 acidic ribosomal protein P0 MTH1681 33 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 15679715 Nonpathogen - hypothetical protein MTH1723 3 None None None 15679610 Nonpathogen - hypothetical protein MTH1615 29 COG2118 COG2118, DNA-binding protein General function prediction only 15679058 Nonpathogen - hypothetical protein MTH1040 1 None None None 15678313 Nonpathogen - hypothetical protein MTH285 1 None None None 15679569 Nonpathogen - hypothetical protein MTH1574 14 COG4022 COG4022, Uncharacterized protein conserved in archaea Function unknown 15679786 Nonpathogen - hypothetical protein MTH1798 1 None None None 15678144 Common - hypothetical protein MTH116 70 COG0778 NfnB, Nitroreductase Energy production and conversion 15679665 Common - hypothetical protein MTH1671 15 COG2000 COG2000, Predicted Fe-S protein General function prediction only 15679705 Common - nitrogenase reductase related protein MTH1711 154 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 15678681 Nonpathogen - hypothetical protein MTH654 2 None None None 15679083 Common - hydrogenase expression/formation protein HypD MTH1072 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15678881 Nonpathogen - hypothetical protein MTH861 28 COG1992 COG1992, Uncharacterized conserved protein Function unknown 15678806 Common - hydrogenase expression/formation protein HypB MTH782 153 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 15679143 Nonpathogen - methyl coenzyme M reductase II, beta subunit MTH1132 14 COG4054 McrB, Methyl coenzyme M reductase, beta subunit Coenzyme metabolism 15678361 Common - GDP-D-mannose dehydratase MTH333 225 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 15678355 Nonpathogen - hypothetical protein MTH327 5 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15679483 Common - hypothetical protein MTH1486 145 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15678096 Nonpathogen - hypothetical protein MTH67 1 None None None 15678085 Nonpathogen - hypothetical protein MTH56 5 COG5643 COG5643, Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E General function prediction only 15679026 Common - DNA topoisomerase VI subunit A MTH1008 34 COG1697 COG1697, DNA topoisomerase VI, subunit A DNA replication, recombination, and repair 15678271 Nonpathogen - hypothetical protein MTH243 19 COG1458 COG1458, Predicted DNA-binding protein containing PIN domain General function prediction only 15679390 Nonpathogen - hypothetical protein MTH1391 19 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 15679321 Common - signal recognition particle protein Srp54 MTH1321 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 15679263 Nonpathogen - hypothetical protein MTH1252 5 None None None 15678042 Nonpathogen - hypothetical protein MTH11 25 COG1588 POP4, RNase P/RNase MRP subunit p29 Translation, ribosomal structure and biogenesis 15678370 Common - succinoglycan biosynthesis transport protein MTH342 142 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 15678129 Nonpathogen - hypothetical protein MTH101 10 COG4883 COG4883, Uncharacterized protein conserved in archaea Function unknown 15679722 Common - phosphate transporter permease PstC homolog MTH1730 228 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 15678462 Nonpathogen - UMP/CMP kinase related protein MTH434 34 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 15679298 Common - methionine aminopeptidase MTH1296 199 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 15679430 Nonpathogen - hypothetical protein MTH1433 2 None None None 15679448 Common - hypothetical protein MTH1451 53 COG3174 COG3174, Predicted membrane protein Function unknown 15678491 Common - hypothetical protein MTH463 34 COG2445 COG2445, Uncharacterized conserved protein Function unknown 15679695 Nonpathogen - hypothetical protein MTH1701 11 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 15678911 Nonpathogen - DNA primase MTH891 34 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15679874 Common - hypothetical protein MTH1892 7 None None None 15679400 Nonpathogen - hypothetical protein MTH1401 18 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 15678122 Nonpathogen - hypothetical protein MTH94 1 None None None 15679439 Common - ketol-acid reductoisomerase MTH1442 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 15678901 Common - hypothetical protein MTH881 12 None None None 15679858 Nonpathogen - hypothetical protein MTH1870 14 COG4051 COG4051, Uncharacterized protein conserved in archaea Function unknown 15679175 Nonpathogen - methyl coenzyme M reductase I, alpha subunit MTH1164 14 COG4058 McrA, Methyl coenzyme M reductase, alpha subunit Coenzyme metabolism 15679311 Nonpathogen - hypothetical protein MTH1311 5 COG1711 COG1711, Uncharacterized protein conserved in archaea Function unknown 15679381 Common - hypothetical protein MTH1382 126 COG0679 COG0679, Predicted permeases General function prediction only 15678572 Common - hypothetical protein MTH544 71 COG0393 COG0393, Uncharacterized conserved protein Function unknown 15679078 Common - Sep-tRNA:Cys-tRNA synthetase MTH1067 125 COG1103 COG1103, Archaea-specific pyridoxal phosphate-dependent enzymes General function prediction only 15679718 Common - citrate synthase MTH1726 188 COG0372 GltA, Citrate synthase Energy production and conversion 15678873 Common - hypothetical protein MTH853 47 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 15678442 Common - asparagine synthetase MTH414 176 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 15678953 Common - hypothetical protein MTH933 6 None None None 15678308 Common - coenzyme F420-reducing hydrogenase, beta subunit homolog MTH280 152 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 15679620 Nonpathogen - hypothetical protein MTH1625 2 None None None 15678095 Nonpathogen - hypothetical protein MTH66 1 None None None 15678627 Nonpathogen - hypothetical protein MTH599 1 None None None 15679250 Common - formate hydrogenlyase, subunit 7 MTH1239 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 15679523 Nonpathogen - hypothetical protein MTH1526 1 None None None 15678393 Common - teichoic acid biosynthesis protein RodC related protein MTH365 32 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 15679582 Common - histidinol-phosphate aminotransferase MTH1587 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 15678108 Nonpathogen - hypothetical protein MTH80 1 None None None 15679340 Nonpathogen - hypothetical protein MTH1340 1 None None None 15678749 Nonpathogen - hypothetical protein MTH722 13 COG1617 COG1617, Uncharacterized conserved protein Function unknown 15678155 Common - deoxyhypusine synthase MTH127 55 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 15679573 Nonpathogen - hypothetical protein MTH1578 19 COG4802 FtrB, Ferredoxin-thioredoxin reductase, catalytic subunit Energy production and conversion 15678781 Common - rubrerythrin MTH756 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 15678675 Nonpathogen rpl37e 50S ribosomal protein L37e MTH648 29 COG2126 RPL37A, Ribosomal protein L37E Translation, ribosomal structure and biogenesis 15679729 Common - formate hydrogenlyase, iron-sulfur subunit I MTH1737 145 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 15678040 Common - ribosomal protein L35 (E.coli L29) MTH9 34 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 15679273 Common - hypothetical protein MTH1262 35 COG0622 COG0622, Predicted phosphoesterase General function prediction only 15678234 Nonpathogen - hypothetical protein MTH206 1 None None None 15679016 Common - carbamoyl phosphate synthase small subunit MTH998 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 15679657 Nonpathogen - adenylate kinase MTH1663 15 COG2019 AdkA, Archaeal adenylate kinase Nucleotide transport and metabolism 15679124 Nonpathogen - hypothetical protein MTH1113 31 COG1303 COG1303, Uncharacterized protein conserved in archaea Function unknown 15679753 Common - thymidylate kinase MTH1765 151 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 15678301 Common - hypothetical protein MTH273 134 COG1881 COG1881, Phospholipid-binding protein General function prediction only 15678893 Common - UDP-N-acetylmuramyl tripeptide synthetase related protein MTH873 15 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 15679073 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit A MTH1062 17 COG4063 MtrA, Tetrahydromethanopterin S-methyltransferase, subunit A Coenzyme metabolism 15678889 Nonpathogen - translation initiation factor IF-5A MTH869 34 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15678838 Common - sporulation protein IVFB related protein MTH816 115 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 15679110 Common - hypothetical protein MTH1099 24 COG0170 SEC59, Dolichol kinase Lipid metabolism 15678977 Common - ATP synthase subunit K MTH959 11 None None None 15679404 Nonpathogen - DNA polymerase II small subunit MTH1405 25 COG1311 HYS2, Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B DNA replication, recombination, and repair 15678725 Nonpathogen - hypothetical protein MTH698 2 None None None 15678105 Nonpathogen - hypothetical protein MTH77 1 None None None 15679488 Common - hypothetical protein MTH1491 29 COG1416 COG1416, Uncharacterized conserved protein Function unknown 15679291 Common - transcriptional regulator HypF homolog MTH1287 109 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15678078 Common - hypothetical protein MTH49 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 15678993 Nonpathogen - hypothetical protein MTH975 16 COG2517 COG2517, Predicted RNA-binding protein containing a C-terminal EMAP domain General function prediction only 15678759 Nonpathogen - hypothetical protein MTH732 4 None None None 15679235 Common - inosine-5'-monophosphate dehydrogenase related protein III MTH1224 164 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 15679542 Common - hypothetical protein MTH1546 115 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 15679420 Common - hypothetical protein MTH1421 39 COG1679 COG1679, Uncharacterized conserved protein Function unknown 15679787 Common - hypothetical protein MTH1799 17 COG0716 FldA, Flavodoxins Energy production and conversion 15678366 Common - LPS biosynthesis RfbU related protein MTH338 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15679019 Common - cation-transporting P-ATPase PacL MTH1001 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 15679059 Common - triosephosphate isomerase MTH1041 38 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 15679698 Common - cobalt transport ATP-binding protein O MTH1704 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15679763 Nonpathogen - hypothetical protein MTH1775 1 None None None 15679470 Common - hypothetical protein MTH1473 40 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 15678805 Common - hypothetical protein MTH781 22 COG1817 COG1817, Uncharacterized protein conserved in archaea Function unknown 15679160 Common - ABC transporter subunit Ycf16 MTH1149 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 15679130 Common rpl10e 50S ribosomal protein L10e MTH1119 66 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 15678965 Nonpathogen - hypothetical protein MTH947 20 COG2232 COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase General function prediction only 15679086 Common - hypothetical protein MTH1075 15 None None None 15678451 Nonpathogen - hypothetical protein MTH423 2 COG4025 COG4025, Predicted membrane protein Function unknown 15678267 Nonpathogen - hypothetical protein MTH239 3 None None None 15678657 Nonpathogen - hypothetical protein MTH629 1 None None None 15678860 Common truA tRNA pseudouridine synthase A MTH840 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 15679264 Nonpathogen - hypothetical protein MTH1253 3 COG3608 COG3608, Predicted deacylase General function prediction only 15678585 Nonpathogen - hypothetical protein MTH557 7 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 15679797 Common ubiA prenyltransferase MTH1809 15 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15678458 Nonpathogen - hypothetical protein MTH430 1 None None None 15678202 Common - sensory transduction histidine kinase MTH174 162 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678432 Common - ribokinase MTH404 204 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 15679666 Common - hypothetical protein MTH1672 29 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 15678590 Common - 3-hydroxy-3-methylglutaryl CoA reductase MTH562 54 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 15679733 Common - hypothetical protein MTH1741 37 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 15679370 Common - hypothetical protein MTH1371 18 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 15679182 Common - phosphonoacetaldehyde methylase MTH1171 233 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 15678176 Common - hypothetical protein MTH148 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 15678580 Common - geranylgeranylglyceryl phosphate synthase-like protein MTH552 30 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 15679647 Nonpathogen - hypothetical protein MTH1652 1 None None None 15679296 Nonpathogen - hypothetical protein MTH1294 4 None None None 15679069 Common - 30S ribosomal protein S7P MTH1056 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 15679357 Nonpathogen - hypothetical protein MTH1358 13 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 15679322 Nonpathogen - hypothetical protein MTH1322 31 COG1258 COG1258, Predicted pseudouridylate synthase Translation, ribosomal structure and biogenesis 15679004 Common - hypothetical protein MTH986 51 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 15678243 Common - FUN34 related protein MTH215 49 COG1584 COG1584, Predicted membrane protein Function unknown 15679210 Nonpathogen - hypothetical protein MTH1199 7 COG2410 COG2410, Uncharacterized conserved protein Function unknown 15678595 Nonpathogen - hypothetical protein MTH567 3 COG2932 COG2932, Predicted transcriptional regulator Transcription 15679479 Common - nitrogenase iron-molybdenum cofactor biosynthesis protein NifE homolog MTH1482 71 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15679260 Nonpathogen - putative monovalent cation/H+ antiporter subunit G MTH1249 5 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 15679259 Nonpathogen - hypothetical protein MTH1248 7 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 15679777 Common - dTDP-glucose 4,6-dehydratase MTH1789 234 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 15679099 Common - hypothetical protein MTH1088 8 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 15678868 Common - preprotein translocase subunit SecF MTH848 116 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 15678633 Common - ABC transporter MTH605 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 15679819 Common - hypothetical protein MTH1831 145 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 15679810 Nonpathogen - hypothetical protein MTH1822 1 None None None 15678143 Common - hypothetical protein MTH115 26 None None None 15679156 Nonpathogen - hypothetical protein MTH1145 7 COG4017 COG4017, Uncharacterized protein conserved in archaea Function unknown 15679525 Common - hypothetical protein MTH1529 92 COG0585 COG0585, Uncharacterized conserved protein Function unknown 15679010 Common - inosine-5'-monophosphate dehydrogenase related protein IX MTH992 178 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 15679887 Nonpathogen - hypothetical protein MTH1905 7 COG3364 COG3364, Zn-ribbon containing protein General function prediction only 15678371 Common - rhamnosyl transferase MTH343 101 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 15679447 Common - hypothetical protein MTH1450 56 COG3174 COG3174, Predicted membrane protein Function unknown 15679537 Nonpathogen - hypothetical protein MTH1541 4 None None None 15678550 Nonpathogen - hypothetical protein MTH522 1 None None None 15678719 Common - stomatin-like protein MTH692 222 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15678347 Nonpathogen - hypothetical protein MTH319 1 None None None 15678137 Nonpathogen - hypothetical protein MTH109 1 None None None 15678335 Common - hypothetical protein MTH307 86 COG0433 COG0433, Predicted ATPase General function prediction only 15678132 Common - multidrug transporter homolog MTH104 228 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15678470 Common - excinuclease ABC subunit B MTH442 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 15679065 Common - DNA-directed RNA polymerase subunit A'' MTH1052 92 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15678490 Nonpathogen - hypothetical protein MTH462 1 None None None 15679090 Nonpathogen - hypothetical protein MTH1079 9 COG1567 COG1567, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15679278 Common - hypothetical protein MTH1267 126 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15678183 Common - rubredoxin MTH155 122 COG1773 COG1773, Rubredoxin Energy production and conversion 15678320 Common - sensory transduction histidine kinase MTH292 85 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678762 Common - hypothetical protein MTH736 196 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15679650 Common - anthranilate synthase component I MTH1655 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15678940 Common - anion permease MTH920 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 15678250 Nonpathogen - hypothetical protein MTH222 3 COG4740 COG4740, Predicted metalloprotease General function prediction only 15678655 Nonpathogen - hypothetical protein MTH627 2 None None None 15678952 Nonpathogen - hypothetical protein MTH932 7 None None None 15679348 Nonpathogen - hypothetical protein MTH1349 15 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 15678608 Common - 3-dehydroquinate synthase MTH580 28 COG1465 COG1465, Predicted alternative 3-dehydroquinate synthase Amino acid transport and metabolism 15679598 Common - acetyl-CoA synthetase MTH1603 207 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15679224 Common - dihydroorotate dehydrogenase 1B MTH1213 216 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 15679615 Common - putative thiazole biosynthetic enzyme MTH1620 31 COG1635 THI4, Flavoprotein involved in thiazole biosynthesis Coenzyme metabolism 15678418 Nonpathogen - hypothetical protein MTH390 8 COG4036 COG4036, Predicted membrane protein Function unknown 15678557 Nonpathogen - hypothetical protein MTH529 4 None None None 15678938 Common - molybdenum formylmethanofuran dehydrogenase, subunit C MTH918 32 COG2218 FwdC, Formylmethanofuran dehydrogenase subunit C Energy production and conversion 15679248 Nonpathogen - NADH dehydrogenase (ubiquinone), subunit 1 related protein MTH1237 16 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 15679365 Nonpathogen - hypothetical protein MTH1366 2 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 15679363 Common - hypothetical protein MTH1364 19 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 15679497 Nonpathogen - hypothetical protein MTH1500 34 COG1339 COG1339, Transcriptional regulator of a riboflavin/FAD biosynthetic operon Transcription / Coenzyme metabolism 15679302 Common - coenzyme F420-reducing hydrogenase, alpha subunit MTH1300 109 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 15678385 Common - hypothetical protein MTH357 32 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 15678523 Common - modification methyltransferase, cytosine-specific MTH495 124 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15679127 Common - glutamate decarboxylase MTH1116 122 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 15679336 Common - mutator MutT protein homolog MTH1336 147 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 15679125 Common upp uracil phosphoribosyltransferase MTH1114 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 15678405 Common - dolichyl-phosphate mannose synthase related protein MTH377 207 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15678303 Nonpathogen - hypothetical protein MTH275 1 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15678463 Nonpathogen - hypothetical protein MTH435 30 COG1701 COG1701, Uncharacterized protein conserved in archaea Function unknown 15678403 Common - UDP-glucose 4-epimerase related protein MTH375 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15679821 Nonpathogen - hypothetical protein MTH1833 3 None None None 15678340 Common - ATP-dependent helicase MTH312 226 COG1201 Lhr, Lhr-like helicases General function prediction only 15679428 Common - bacitracin resistance protein MTH1429 187 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 15679807 Common - ferredoxin MTH1819 8 COG1141 Fer, Ferredoxin Energy production and conversion 15679727 Common - fumarate hydratase MTH1735 134 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 15678257 Nonpathogen - hypothetical protein MTH229 1 None None None 15678284 Nonpathogen rps28e 30S ribosomal protein S28e MTH256 33 COG2053 RPS28A, Ribosomal protein S28E/S33 Translation, ribosomal structure and biogenesis 15678499 Common - hypothetical protein MTH471 7 COG3339 COG3339, Uncharacterized conserved protein Function unknown 15678832 Common - DNA helicase related protein MTH810 122 COG1204 COG1204, Superfamily II helicase General function prediction only 15679288 Common - hypothetical protein MTH1284 24 COG0456 RimI, Acetyltransferases General function prediction only 15678327 Common - DNA-directed RNA polymerase subunit alpha MTH299 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15679047 Nonpathogen - hypothetical protein MTH1029 1 None None None 15679423 Common - hypothetical protein MTH1424 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 15678972 Common - V-type ATP synthase subunit B MTH954 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 15679271 Common - sensory transduction histidine kinase MTH1260 86 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15679402 Common - precorrin-3 methylase MTH1403 154 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 15679659 Nonpathogen - hypothetical protein MTH1665 25 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 15678456 Nonpathogen - hypothetical protein MTH428 1 None None None 15679782 Nonpathogen - hypothetical protein MTH1794 1 None None None 15679617 Nonpathogen - hypothetical protein MTH1622 15 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 15678895 Common - 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein MTH875 191 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15678429 Common - polyferredoxin MTH401 75 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 15678502 Nonpathogen - hypothetical protein MTH474 10 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 15678758 Nonpathogen - hypothetical protein MTH731 4 None None None 15678098 Nonpathogen - hypothetical protein MTH70 1 None None None 15678123 Nonpathogen - hypothetical protein MTH95 1 None None None 15678606 Nonpathogen - hypothetical protein MTH578 4 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 15678239 Nonpathogen - hypothetical protein MTH211 1 None None None 15679895 Common - hypothetical protein MTH1913 25 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15678449 Nonpathogen - hypothetical protein MTH421 11 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15679269 Common - potassium channel related protein MTH1258 162 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 15678979 Nonpathogen - hypothetical protein MTH961 3 None None None 15679741 Nonpathogen - hypothetical protein MTH1749 4 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 15678551 Nonpathogen - hypothetical protein MTH523 2 None None None 15678033 Common rpl3p 50S ribosomal protein L3P MTH2 182 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 15678684 Common - acyl-CoA synthetase MTH657 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15679208 Nonpathogen - hypothetical protein MTH1197 5 COG4077 COG4077, Uncharacterized protein conserved in archaea Function unknown 15678917 Common - pyrroline-5-carboxylate reductase MTH897 144 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 15679112 Common - hypothetical protein MTH1101 54 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 15679622 Nonpathogen - transcription factor MTH1627 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 15679575 Common - DNA ligase MTH1580 108 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 15679436 Nonpathogen - hypothetical protein MTH1439 1 None None None 15678399 Nonpathogen - hypothetical protein MTH371 3 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 15678292 Common - DNA-directed RNA polymerase subunit E' MTH264 38 COG1095 RPB7, DNA-directed RNA polymerase, subunit E' Transcription 15678723 Common - ABC transporter (glutamine transport ATP-binding protein) MTH696 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15678975 Common - V-type ATP synthase subunit C MTH957 31 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 15678278 Nonpathogen - tRNA-splicing endonuclease subunit alpha MTH250 34 COG1676 SEN2, tRNA splicing endonuclease Translation, ribosomal structure and biogenesis 15678871 Nonpathogen - hypothetical protein MTH851 2 None None None 15678511 Nonpathogen - hypothetical protein MTH483 5 COG1615 COG1615, Uncharacterized conserved protein Function unknown 15678566 Nonpathogen - hypothetical protein MTH538 4 None None None 15679176 Nonpathogen - methyl coenzyme M reductase I, gamma subunit MTH1165 14 COG4057 McrG, Methyl coenzyme M reductase, gamma subunit Coenzyme metabolism 15678358 Nonpathogen - hypothetical protein MTH330 5 None None None 15678577 Common - sensory transduction regulatory protein MTH549 95 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 15678492 Nonpathogen - hypothetical protein MTH464 5 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 15678750 Common - 2-isopropylmalate synthase MTH723 221 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 15678509 Common - H+-transporting ATPase MTH481 218 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 15678903 Nonpathogen - hypothetical protein MTH883 3 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15679162 Nonpathogen - hypothetical protein MTH1151 5 COG1873 COG1873, Uncharacterized conserved protein Function unknown 15679507 Common - NH(3)-dependent NAD+ synthetase MTH1510 217 COG0171 NadE, NAD synthase Coenzyme metabolism 15678661 Common - hypothetical protein MTH633 23 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 15679869 Nonpathogen - hypothetical protein MTH1881 6 COG4010 COG4010, Uncharacterized protein conserved in archaea Function unknown 15679632 Nonpathogen - hypothetical protein MTH1637 1 None None None 15678886 Common - adenine deaminase MTH866 70 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 15678937 Nonpathogen - molybdenum formylmethanofuran dehydrogenase, subunit E MTH917 15 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 15678518 Nonpathogen - hypothetical protein MTH490 1 None None None 15678325 Nonpathogen - DNA-dependent RNA polymerase, subunit A' MTH297 34 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15679853 Nonpathogen - hypothetical protein MTH1865 14 COG4070 COG4070, Predicted peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family Posttranslational modification, protein turnover, chaperones 15678063 Common - H/ACA RNA-protein complex component Cbf5p MTH32 243 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 15679216 Common - malate dehydrogenase MTH1205 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 15678116 Nonpathogen - hypothetical protein MTH88 1 None None None 15678729 Common - acetyl-CoA synthetase related protein MTH702 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15678480 Nonpathogen - hypothetical protein MTH452 1 None None None 15678991 Common - L-aspartate dehydrogenase MTH973 49 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 15678570 Nonpathogen - hypothetical protein MTH542 13 COG0433 COG0433, Predicted ATPase General function prediction only 15679744 Common - methylenetetrahydromethanopterin reductase MTH1752 81 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 15678214 Nonpathogen - hypothetical protein MTH186 1 None None None 15679141 Nonpathogen - methyl coenzyme M reductase II, gamma subunit MTH1130 14 COG4057 McrG, Methyl coenzyme M reductase, gamma subunit Coenzyme metabolism 15679734 Common - hypothetical protein MTH1742 163 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15679515 Nonpathogen - hypothetical protein MTH1518 1 None None None 15679485 Common - hypothetical protein MTH1488 21 COG1695 COG1695, Predicted transcriptional regulators Transcription 15678367 Nonpathogen - hypothetical protein MTH339 8 COG4906 COG4906, Predicted membrane protein Function unknown 15679133 Common - seryl-tRNA synthetase MTH1122 30 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678740 Nonpathogen - hypothetical protein MTH713 1 None None None 15678774 Common - chorismate synthase MTH748 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 15679409 Nonpathogen - hypothetical protein MTH1410 5 COG5440 COG5440, Uncharacterized conserved protein Function unknown 15678926 Common - hypothetical protein MTH906 18 COG3543 COG3543, Uncharacterized conserved protein Function unknown 15679338 Common - peptidyl-prolyl cis-trans isomerase B MTH1338 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 161484929 Common argC N-acetyl-gamma-glutamyl-phosphate reductase MTH846 216 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 15679057 Nonpathogen - hypothetical protein MTH1039 34 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 15679553 Common - tungsten formylmethanofuran dehydrogenase, subunit A MTH1557 29 COG1229 FwdA, Formylmethanofuran dehydrogenase subunit A Energy production and conversion 15679562 Common - nitrogenase molybdenum-iron protein, NifN subunit MTH1566 55 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15678489 Nonpathogen - hypothetical protein MTH461 1 None None None 15679037 Common - F420-0--gamma-glutamyl ligase MTH1019 43 COG1478 COG1478, Uncharacterized conserved protein Function unknown 15679418 Nonpathogen - hypothetical protein MTH1419 1 None None None 15679902 Common - TPR-repeat-containing protein MTH68 192 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15679391 Common - dolichyl-phosphate mannoosyltransferase related protein MTH1392 207 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15678346 Common - cobalamin biosynthesis protein N MTH318 80 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15679413 Common - protein-L-isoaspartate methyltransferase homolog MTH1414 63 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 15679387 Common - 3-isopropylmalate dehydrogenase MTH1388 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 15678825 Nonpathogen rps17E 30S ribosomal protein S17e MTH803 33 COG1383 RPS17A, Ribosomal protein S17E Translation, ribosomal structure and biogenesis 15679707 Common - acetyl-CoA decarbonylase/synthase complex subunit gamma MTH1713 23 COG1456 CdhE, CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) Energy production and conversion 15679832 Nonpathogen - hypothetical protein MTH1844 10 COG4742 COG4742, Predicted transcriptional regulator Transcription 15678153 Nonpathogen - hypothetical protein MTH125 1 None None None 15678440 Common - hypothetical protein MTH412 14 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 15678544 Nonpathogen - hypothetical protein MTH516 1 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 15678240 Common - exodeoxyribonuclease MTH212 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15678694 Nonpathogen - hypothetical protein MTH667 1 None None None 15678082 Nonpathogen - hypothetical protein MTH53 1 None None None 15679567 Common - molybdopterin biosynthesis protein MoeB homolog MTH1571 220 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 15678640 Nonpathogen - hypothetical protein MTH612 1 None None None 15679352 Nonpathogen - hypothetical protein MTH1353 8 None None None 15678709 Common - exosome complex RNA-binding protein Rrp42 MTH682 49 COG2123 COG2123, RNase PH-related exoribonuclease Translation, ribosomal structure and biogenesis 15678538 Common - hypothetical protein MTH510 8 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15679468 Common - O-antigen transporter homolog MTH1471 106 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 15678056 Nonpathogen rpl15p 50S ribosomal protein L15P MTH25 46 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 15679638 Common - pyruvate formate-lyase activating enzyme related protein MTH1643 40 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 15678579 Common - DNA helicase II related protein MTH551 37 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15679768 Common - stomatin-like protein MTH1780 207 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15679030 Common hemA glutamyl-tRNA reductase MTH1012 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 15678193 Nonpathogen - signal recognition particle 19 kDa protein MTH165 28 COG1400 SEC65, Signal recognition particle 19 kDa protein Intracellular trafficking and secretion 15679372 Nonpathogen - hypothetical protein MTH1373 10 COG0170 SEC59, Dolichol kinase Lipid metabolism 15678145 Nonpathogen - hypothetical protein MTH117 2 None None None 15679006 Common - hypothetical protein MTH988 25 COG3482 COG3482, Uncharacterized conserved protein Function unknown 15678844 Common - rubrerythrin MTH822 81 COG1592 COG1592, Rubrerythrin Energy production and conversion 15679527 Nonpathogen - hypothetical protein MTH1531 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 15678918 Common - hypothetical protein MTH898 167 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15678245 Common - acetyl-CoA synthetase MTH217 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15679645 Nonpathogen - hypothetical protein MTH1650 1 None None None 15678785 Common - Na+/H+-exchanging protein:Na+/H+ antiporter MTH760 12 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 15678052 Nonpathogen rpl19e 50S ribosomal protein L19e MTH21 34 COG2147 RPL19A, Ribosomal protein L19E Translation, ribosomal structure and biogenesis 15678852 Common - hypothetical protein MTH832 34 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 15679212 Nonpathogen purP 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase MTH1201 20 COG1759 COG1759, ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) General function prediction only 15679150 Common - formate dehydrogenase, beta subunit related protein FlpB MTH1139 33 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 15679067 Common nusA transcription elongation factor NusA-like protein MTH1054 121 COG0195 NusA, Transcription elongation factor Transcription 15678999 Common - aminopeptidase P MTH981 245 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15678906 Nonpathogen - H/ACA RNA-protein complex component Gar1 MTH886 9 COG3277 GAR1, RNA-binding protein involved in rRNA processing Translation, ribosomal structure and biogenesis 15679480 Nonpathogen - chromatin protein MTH1483 28 COG1581 Ssh10b, Archaeal DNA-binding protein Transcription 15679257 Common - hydrogenase subunit F MTH1246 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 15679565 Nonpathogen - hypothetical protein MTH1569 16 COG1693 COG1693, Uncharacterized protein conserved in archaea Function unknown 15679596 Common - aspartate aminotransferase MTH1601 179 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 15678151 Common - sensory transduction histidine kinase MTH123 98 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 15678220 Common - tungsten formylmethanofuran dehydrogenase, subunit C homolog MTH192 61 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 15678411 Nonpathogen - hypothetical protein MTH383 1 None None None 15679605 Nonpathogen - ribosomal protein L18a MTH1610 9 COG2157 RPL20A, Ribosomal protein L20A (L18A) Translation, ribosomal structure and biogenesis 15679817 Common - hypothetical protein MTH1829 9 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 15679814 Common - unknown (contains ferredoxin domain) MTH1826 40 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 15679517 Common - potassium channel related protein MTH1520 129 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15678744 Nonpathogen - hypothetical protein MTH717 3 COG1572 COG1572, Uncharacterized conserved protein Function unknown 15679106 Common - hypothetical protein MTH1095 23 None None None 15678170 Common - inosine-5'-monophosphate dehydrogenase MTH142 244 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15679828 Common - cell division inhibitor MTH1840 242 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15679169 Nonpathogen mtrF tetrahydromethanopterin S-methyltransferase subunit F MTH1158 5 COG4218 MtrF, Tetrahydromethanopterin S-methyltransferase, subunit F Coenzyme metabolism 15679226 Nonpathogen - fibrillarin MTH1215 34 COG1889 NOP1, Fibrillarin-like rRNA methylase Translation, ribosomal structure and biogenesis 15679158 Nonpathogen - hypothetical protein MTH1147 7 COG4015 COG4015, Predicted dinucleotide-utilizing enzyme of the ThiF/HesA family General function prediction only 15679795 Common - phytoene dehydrogenase MTH1807 100 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 15678260 Common - hypothetical protein MTH232 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15679857 Common - activator of (R)-2-hydroxyglutaryl-CoA MTH1869 64 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 15678484 Common - magnesium chelatase subunit MTH456 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15678401 Common - dTDP-glucose 4,6-dehydratase related protein MTH373 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15679148 Nonpathogen - conserved protein (FlpA) MTH1137 7 COG4018 COG4018, Uncharacterized protein conserved in archaea Function unknown 15678834 Nonpathogen - hypothetical protein MTH812 12 COG4066 COG4066, Uncharacterized protein conserved in archaea Function unknown 15679012 Common - chlorohydrolase MTH994 134 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15678421 Common - NADH dehydrogenase (ubiquinone), subunit 1 related protein MTH393 73 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 15679785 Common - hypothetical protein MTH1797 88 COG1720 COG1720, Uncharacterized conserved protein Function unknown 15678229 Nonpathogen - hypothetical protein MTH201 1 None None None 15678888 Common - agmatine ureohydrolase MTH868 144 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 15678177 Common - molybdenum cofactor biosynthesis protein MoaE MTH149 82 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 15678707 Nonpathogen - hypothetical protein MTH680 11 COG2136 IMP4, Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain Translation, ribosomal structure and biogenesis / RNA processing and modification 15679759 Nonpathogen - hypothetical protein MTH1771 1 None None None 15678663 Nonpathogen - hypothetical protein MTH635 1 None None None 15679580 Common - O-linked GlcNAc transferase MTH1585 168 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15679472 Nonpathogen - hypothetical protein MTH1475 1 None None None 15679559 Common - nitrogenase NifD subunit MTH1563 63 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15678364 Nonpathogen - hypothetical protein MTH336 1 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15678597 Common - heat shock protein X MTH569 193 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15679305 Common - hypothetical protein MTH1305 34 COG1379 COG1379, Uncharacterized conserved protein Function unknown 15678967 Nonpathogen - hypothetical protein MTH949 10 COG2083 COG2083, Uncharacterized protein conserved in archaea Function unknown 15679593 Common - hypothetical protein MTH1598 45 COG1371 COG1371, Uncharacterized conserved protein Function unknown 15678803 Nonpathogen - hypothetical protein MTH778 4 None None None 15678472 Common - sensory transduction histidine kinase MTH444 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 15679585 Common - phosphomannomutase MTH1590 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15678333 Nonpathogen - hypothetical protein MTH305 5 None None None 15678988 Common - phosphoglycerate dehydrogenase MTH970 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15679699 Common - cobalt transport membrane protein MTH1705 66 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 15678984 Nonpathogen - hypothetical protein MTH966 33 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 15678059 Nonpathogen - hypothetical protein MTH28 22 COG1422 COG1422, Predicted membrane protein Function unknown 15679903 Common murE UDP-MurNac-tripeptide synthetase MTH734 192 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15678430 Nonpathogen - hypothetical protein MTH402 5 COG4030 COG4030, Uncharacterized protein conserved in archaea Function unknown 15678649 Nonpathogen - hypothetical protein MTH621 4 None None None 15679544 Common - NADH dehydrogenase subunit E MTH1548 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 15678269 Common rfc replication factor C small subunit MTH241 249 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 15679498 Common - O-phosphoseryl-tRNA synthetase MTH1501 61 COG2024 COG2024, Phenylalanyl-tRNA synthetase alpha subunit (archaeal type) Translation, ribosomal structure and biogenesis 15679491 Common - hypothetical protein MTH1494 55 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 15678920 Common - hypothetical protein MTH900 138 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 15679361 Common - hypothetical protein MTH1362 40 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 15678850 Common - hypothetical protein MTH830 38 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 15678555 Nonpathogen - hypothetical protein MTH527 1 None None None 15678997 Nonpathogen - hypothetical protein MTH979 1 None None None 15679377 Common - phycocyanin alpha phycocyanobilin lyase CpcE MTH1378 48 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15678216 Common - malate dehydrogenase MTH188 193 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 15678601 Nonpathogen - hypothetical protein MTH573 2 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 15678208 Nonpathogen - hypothetical protein MTH180 4 None None None 15679823 Nonpathogen - hypothetical protein MTH1835 15 COG2074 COG2074, 2-phosphoglycerate kinase Carbohydrate transport and metabolism 15678569 Common - Rad32 related protein MTH541 85 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 15679129 Common - phosphoenolpyruvate synthase MTH1118 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15679456 Nonpathogen - hypothetical protein MTH1459 1 None None None 15678528 Nonpathogen - hypothetical protein MTH500 2 None None None 15679334 Common - diaminopimelate epimerase MTH1334 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 15678139 Nonpathogen - hypothetical protein MTH111 1 None None None 15678611 Common - hypothetical protein MTH583 103 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 15679426 Nonpathogen - hypothetical protein MTH1427 1 None None None 15679346 Common - probable ATP-dependent helicase MTH1347 25 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 15678527 Nonpathogen - hypothetical protein MTH499 2 None None None 15679843 Common - coenzyme F390 synthetase II MTH1855 133 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 15678076 Common - hypothetical protein MTH47 92 COG1608 COG1608, Predicted archaeal kinase General function prediction only 15679509 Nonpathogen - H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein MTH1512 6 COG4007 COG4007, Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase General function prediction only 15678408 Common - UDP-glucose 4-epimerase homolog MTH380 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15678521 Nonpathogen - hypothetical protein MTH493 1 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 15678349 Nonpathogen - hypothetical protein MTH321 4 COG1598 COG1598, Uncharacterized conserved protein Function unknown 15678892 Common ppnK inorganic polyphosphate/ATP-NAD kinase MTH872 241 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 15678185 Common - flavoprotein A homolog (III) MTH157 91 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 15678087 Nonpathogen - hypothetical protein MTH58 1 None None None 15678541 Nonpathogen - hypothetical protein MTH513 3 None None None 15679535 Common - anaerobic ribonucleoside-triphosphate reductase MTH1539 103 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 15678128 Nonpathogen - hypothetical protein MTH100 3 None None None 15678383 Nonpathogen - hypothetical protein MTH355 1 None None None 15678322 Nonpathogen - hypothetical protein MTH294 1 None None None 15678955 Common - hypothetical protein MTH935 22 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 15678859 Nonpathogen - hypothetical protein MTH839 26 COG2433 COG2433, Uncharacterized conserved protein Function unknown 15679848 Common - uridine 5'-monophosphate synthase MTH1860 232 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 15679891 Nonpathogen - hypothetical protein MTH1909 23 COG3356 COG3356, Predicted membrane protein Function unknown 15678506 Common - sulfate transport system permease protein MTH478 226 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 15679329 Common - methyltransferase related protein MTH1329 171 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15678192 Nonpathogen - single-stranded DNA exonuclease RecJ related protein MTH164 25 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15679487 Common - hypothetical protein MTH1490 37 COG3548 COG3548, Predicted integral membrane protein Function unknown 15678592 Nonpathogen - hypothetical protein MTH564 6 COG4053 COG4053, Uncharacterized protein conserved in archaea Function unknown 15678583 Common - magnesium chelatase subunit MTH555 67 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 15678942 Common - hypothetical protein MTH922 10 COG2014 COG2014, Uncharacterized conserved protein Function unknown 15679088 Nonpathogen - hypothetical protein MTH1077 1 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 15679196 Common - translation elongation factor, EF-1 alpha related protein MTH1185 249 COG5258 GTPBP1, GTPase General function prediction only 15679045 Common - CDP-diacylglycerol-serine O-phosphatidyltransferase MTH1027 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 15678819 Nonpathogen - hypothetical protein MTH797 2 None None None 15678931 Common - probable surface protein MTH911 60 None None None 15678899 Common - uridine monophosphate kinase MTH879 244 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 15678764 Nonpathogen - hypothetical protein MTH738 8 COG4076 COG4076, Predicted RNA methylase General function prediction only 15678713 Common - proteasome subunit alpha MTH686 42 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 15678792 Common valS valyl-tRNA synthetase MTH767 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15679217 Common - phosphonopyruvate decarboxylase related protein MTH1206 34 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 15678957 Nonpathogen - hypothetical protein MTH937 3 None None None 15678035 Common - ribosomal protein L23a (E.coli L23) MTH4 83 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 15678134 Common - tungsten formylmethanofuran dehydrogenase, subunit C homolog MTH106 61 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 15679560 Common - nitrogenase molybdenum-iron protein, NifK subunit MTH1564 55 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 15679295 Common - DnaJ protein MTH1291 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15679577 Common - carbonic anhydrase MTH1582 85 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 15678915 Common - hypothetical protein MTH895 62 None None None 15678686 Common - epoxidase MTH659 124 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 15678575 Common - hypothetical protein MTH547 126 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15679434 Nonpathogen - hypothetical protein MTH1437 1 None None None 15679074 Common - transcriptional regulator related protein MTH1063 90 COG1309 AcrR, Transcriptional regulator Transcription 15679870 Common - hypothetical protein MTH1882 51 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 15679624 Common - hypothetical protein MTH1629 44 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 15678374 Common - formate acetyltransferase 2 MTH346 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 15678878 Common - GTP-binding protein, GTP1/OBG family MTH858 242 COG1084 COG1084, Predicted GTPase General function prediction only 15678091 Common - molybdenum cofactor biosynthesis A (MoaA) related protein MTH62 91 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15678670 Common - nitrogenase reductase-like protein MTH643 73 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 15679320 Common - adenine phosphoribosyltransferase MTH1320 70 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15679754 Nonpathogen - hypothetical protein MTH1766 1 None None None 15678397 Common - UDP-N-acetylglucosamine pyrophosphorylase related protein MTH369 59 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 15679178 Nonpathogen - methyl coenzyme M reductase I, D protein MTH1167 14 COG4055 McrD, Methyl coenzyme M reductase, subunit D Coenzyme metabolism 15679725 Nonpathogen - hypothetical protein MTH1733 1 COG1667 COG1667, Uncharacterized protein conserved in archaea Function unknown 15678767 Nonpathogen - hypothetical protein MTH741 3 None None None 15678305 Common - bacteriochlorophyll synthase 43 kDa subunit MTH277 122 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 15679350 Common - hypothetical protein MTH1351 16 COG1592 COG1592, Rubrerythrin Energy production and conversion 15679190 Common - hypothetical protein MTH1179 82 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 15678047 Common rpl5p 50S ribosomal protein L5P MTH16 239 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 15678230 Nonpathogen - hypothetical protein MTH202 1 None None None 15678211 Common - acetylglutamate kinase MTH183 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 15679686 Common - hypothetical protein MTH1692 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 15679739 Common - hypothetical protein MTH1747 24 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 15679611 Nonpathogen - 30S ribosomal protein S19e MTH1616 34 COG2238 RPS19A, Ribosomal protein S19E (S16A) Translation, ribosomal structure and biogenesis 15678074 Common - hypothetical protein MTH45 71 COG1355 COG1355, Predicted dioxygenase General function prediction only 15678332 Common - hypothetical protein MTH304 26 COG2445 COG2445, Uncharacterized conserved protein Function unknown 15678897 Nonpathogen ubiA prenyltransferase MTH877 8 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15679889 Common - hypothetical protein MTH1907 60 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 15678512 Nonpathogen - hypothetical protein MTH484 1 None None None 15679896 Common - hypothetical protein MTH1914 36 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 15679417 Common - hypothetical protein MTH1418 27 COG2043 COG2043, Uncharacterized protein conserved in archaea Function unknown 15678101 Nonpathogen - hypothetical protein MTH73 1 None None None 15678756 Nonpathogen - hypothetical protein MTH729 32 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 15679458 Nonpathogen - hypothetical protein MTH1461 6 COG1822 COG1822, Predicted archaeal membrane protein Function unknown 15679411 Nonpathogen - Cdc6 related protein MTH1412 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 15679838 Common - succinate dehydrogenase/fumarate reductase iron-sulfur subunit MTH1850 222 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 15678500 Common - DNA helicase II MTH472 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15678720 Common - hypothetical protein MTH693 13 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15679652 Common - indole-3-glycerol phosphate synthase MTH1657 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 15678188 Common - superoxide dismutase (Fe/Mn) MTH160 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 15679441 Common - acetolactate synthase catalytic subunit MTH1444 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 15678311 Nonpathogen - protein kinase MTH283 1 None None None 15678613 Nonpathogen - DNA primase small subunit MTH585 31 COG1467 PRI1, Eukaryotic-type DNA primase, catalytic (small) subunit DNA replication, recombination, and repair 15679700 Nonpathogen - cobalt transport protein CbiN MTH1706 6 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 15679206 Nonpathogen - hypothetical protein MTH1195 4 COG4024 COG4024, Uncharacterized protein conserved in archaea Function unknown 15678227 Nonpathogen - hypothetical protein MTH199 2 None None None 15678659 Common - UDP-glucose 4-epimerase MTH631 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 15678161 Common - cobalt transport ATP-binding protein O MTH133 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 15678688 Common - ammonium transporter MTH661 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 15679021 Common - molybdenum cofactor biosynthesis protein MoeA MTH1003 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 15679267 Common - hypothetical protein MTH1256 213 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 15679860 Common - translation initiation factor eIF-2B, alpha subunit MTH1872 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 15679393 Common - hypothetical protein MTH1394 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 15678294 Nonpathogen - hypothetical protein MTH266 30 COG1909 COG1909, Uncharacterized protein conserved in archaea Function unknown 15679746 Common - phosphomannomutase MTH1758 237 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15679286 Common - inosine-5'-monophosphate dehydrogenase related protein VI MTH1282 180 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 15679043 Nonpathogen - hypothetical protein MTH1025 2 None None None 15679115 Nonpathogen - hypothetical protein MTH1104 1 None None None 15678389 Common - teichoic acid biosynthesis protein RodC related protein MTH361 33 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 15679359 Nonpathogen - hypothetical protein MTH1360 1 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 15679407 Common - cobalamin biosynthesis protein G MTH1408 101 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 15679639 Nonpathogen - hypothetical protein MTH1644 5 None None None 15679642 Nonpathogen - hypothetical protein MTH1647 3 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 15678392 Nonpathogen - hypothetical protein MTH364 1 None None None 15678635 Nonpathogen - hypothetical protein MTH607 1 None None None 15678692 Nonpathogen - hypothetical protein MTH665 1 None None None 15678272 Common hisS histidyl-tRNA synthetase MTH244 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15679634 Common - cell division control protein Cdc48 MTH1639 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 15678890 Nonpathogen - hypothetical protein MTH870 26 COG1945 COG1945, Uncharacterized conserved protein Function unknown 15679692 Common - delta 1-pyrroline-5-carboxylate synthetase MTH1698 20 COG2054 COG2054, Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases General function prediction only 15678054 Common rps5p 30S ribosomal protein S5P MTH23 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 15679138 Common - dihydroorotase MTH1127 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 15678827 Nonpathogen - conserved protein (homoserine kinase related) MTH805 26 COG1685 COG1685, Archaeal shikimate kinase Amino acid transport and metabolism / Coenzyme metabolism 15678536 Nonpathogen - hypothetical protein MTH508 3 None None None 15678568 Common - intracellular protein transport protein MTH540 122 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 15678454 Nonpathogen - hypothetical protein MTH426 1 None None None 15679551 Nonpathogen - tungsten formylmethanofuran dehydrogenase, subunit G MTH1555 20 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15679466 Common - molybdenum transport ATP-binding protein homolog MTH1469 4 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 15679709 Common - phycocyanin alpha phycocyanobilin lyase CpcE related protein MTH1715 48 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 15679318 Nonpathogen - exosome complex RNA-binding protein Csl4 MTH1318 22 COG1096 COG1096, Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) Translation, ribosomal structure and biogenesis 15678820 Common - bacitracin transport permease related protein MTH798 133 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15679681 Nonpathogen - hypothetical protein MTH1687 14 COG2454 COG2454, Uncharacterized conserved protein Function unknown 15678465 Common - endo-1,4-beta-glucanase MTH437 85 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 15678482 Common - methyl coenzyme M reductase system, component A2 homolog MTH454 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 15678111 Common - O-linked GlcNAc transferase MTH83 198 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 15678908 Common - hypothetical protein MTH888 72 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 15679710 Nonpathogen - hypothetical protein MTH1716 2 None None None 15678734 Common - glutamyl-tRNA(Gln) amidotransferase subunit E MTH707 213 COG2511 GatE, Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) Translation, ribosomal structure and biogenesis 15679775 Common - hypothetical protein MTH1787 104 COG1309 AcrR, Transcriptional regulator Transcription 15678114 Nonpathogen - hypothetical protein MTH86 1 None None None 15679793 Nonpathogen - hypothetical protein MTH1805 3 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 15678621 Common - hypothetical protein MTH593 42 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 15679380 Common - heterodisulfide reductase, subunit A MTH1381 70 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 15678700 Common - magnesium chelatase subunit MTH673 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 15678089 Nonpathogen - hypothetical protein MTH60 1 None None None 15679398 Nonpathogen - hypothetical protein MTH1399 3 None None None 161484930 Common pheT phenylalanyl-tRNA synthetase subunit beta MTH770 220 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 15679607 Nonpathogen - 50S ribosomal protein L31e MTH1612 32 COG2097 RPL31A, Ribosomal protein L31E Translation, ribosomal structure and biogenesis 15679583 Common - ferripyochelin binding protein MTH1588 216 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 15679444 Common argS arginyl-tRNA synthetase MTH1447 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15678817 Common - hypothetical protein MTH795 81 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 15679736 Common - hypothetical protein MTH1744 40 COG1578 COG1578, Uncharacterized conserved protein Function unknown 15679255 Nonpathogen - hypothetical protein MTH1244 5 None None None 15679855 Nonpathogen - hypothetical protein MTH1867 11 COG4048 COG4048, Uncharacterized protein conserved in archaea Function unknown 15678810 Common - sensory transduction histidine kinase related protein MTH786 162 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 15679669 Common - hypothetical protein MTH1675 20 COG1751 COG1751, Uncharacterized conserved protein Function unknown 15679332 Nonpathogen - hypothetical protein MTH1332 1 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 15679743 Nonpathogen - hypothetical protein MTH1751 25 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 15678125 Nonpathogen - hypothetical protein MTH97 1 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only