Helicobacter pylori 26695, complete genome NC_000915 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 15645905 Common rplQ 50S ribosomal protein L17 HP1292 215 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 15645653 Common - hypothetical protein HP1039 6 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 15645815 Common rplA 50S ribosomal protein L1 HP1201 246 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 15644703 Common - bifunctional urease subunit gamma/beta HP0073 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 15644734 Common - 2',3'-cyclic-nucleotide 2'-phosphodiesterase (cpdB) HP0104 104 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 161353438 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase HP1335 214 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 15645256 Common - quinone-reactive Ni/Fe hydrogenase, large subunit (hydB) HP0632 105 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 15644670 Pathogen - NADH-ubiquinone oxidoreductase subunit HP0037 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 15645518 Common - hydrogenase expression/formation protein (hypB) HP0900 110 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 15645268 Common - hypothetical protein HP0644 34 COG0762 COG0762, Predicted integral membrane protein Function unknown 15646118 Common - hypothetical protein HP1509 169 COG0344 COG0344, Predicted membrane protein Function unknown 15645162 Pathogen - cag pathogenicity island protein (cag15) HP0536 1 None None None 15645678 Pathogen - hypothetical protein HP1064 1 None None None 15645280 Common - hypothetical protein HP0656 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 15645855 Common alaS alanyl-tRNA synthetase HP1241 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645016 Common - hypothetical protein HP0388 52 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15645642 Pathogen - hypothetical protein HP1028 1 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 15645126 Common - phospholipase A1 precursor (DR-phospholipase A) HP0499 41 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 15644895 Common - chlorohydrolase HP0267 72 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 15644792 Common - delta-aminolevulinic acid dehydratase HP0163 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 15645080 Common - hypothetical protein HP0452 36 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 15645511 Pathogen - hypothetical protein HP0893 1 None None None 15645571 Common - prolipoprotein diacylglyceryl transferase HP0955 191 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 15645132 Common - hypothetical protein HP0505 2 None None None 15645631 Common - amino acid permease (rocE) HP1017 156 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 15645525 Pathogen - hypothetical protein HP0909 1 None None None 15646044 Common - protease IV (PspA) HP1435 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15646150 Common - toxR-activated gene (tagE) HP1543 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15645573 Common - 3-deoxy-D-manno-octulosonic-acid transferase HP0957 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 15645087 Common - virB4 homolog (virB4) HP0459 51 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 15645370 Common - flagellar protein FlaG HP0751 12 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 15645441 Common - homoserine dehydrogenase HP0822 215 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 15644837 Pathogen - hypothetical protein HP0209 1 None None None 15645064 Pathogen - hypothetical protein HP0436 1 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 15645663 Common - hypothetical protein HP1049 4 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 15645946 Pathogen - hypothetical protein HP1333 1 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 15645884 Common - NADH dehydrogenase subunit K HP1270 165 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 15645608 Pathogen - hypothetical protein HP0993 1 None None None 15645799 Common - sugar efflux transporter HP1185 121 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15644844 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase HP0216 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 15646050 Common - peptidyl-prolyl cis-trans isomerase B, cyclosporin-type rotamase (ppi) HP1441 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 15644718 Common - RNA polymerase sigma factor RpoD HP0088 217 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 15645200 Common - hypothetical protein HP0575 79 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 15644654 Common - lipid A 1-phosphatase HP0021 3 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15646190 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase HP1583 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 15646138 Common - purine nucleoside phosphorylase (punB) HP1530 7 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15645597 Pathogen - hypothetical protein HP0982 1 None None None 15645274 Common - hypothetical protein HP0650 4 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 15645410 Common - cadmium-transporting ATPase, P-type (cadA) HP0791 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15644821 Common - fumarate reductase HP0192 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 15645085 Common - hypothetical protein HP0457 2 None None None 15645402 Pathogen - hypothetical protein HP0783 1 None None None 15645974 Common - replicative DNA helicase HP1362 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 15645532 Common - iron-regulated outer membrane protein (frpB) HP0916 49 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15645291 Pathogen - hypothetical protein HP0667 1 COG4889 COG4889, Predicted helicase General function prediction only 15644955 Common - flagellar protein G (flaG) HP0327 17 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 15645302 Pathogen - hypothetical protein HP0678 1 None None None 15645419 Common - molybdopterin converting factor, subunit 2 (moaE) HP0800 13 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 15645794 Common - pyrimidine nucleoside transport protein (nupC) HP1180 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 15645116 Common - hypothetical protein HP0489 23 None None None 15644729 Common - methyl-accepting chemotaxis protein (tlpA) HP0099 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15645409 Common - anti-codon nuclease masking agent (prrB) HP0790 72 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 15644753 Common thrS threonyl-tRNA synthetase HP0123 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645823 Pathogen - ulcer-associated gene restriction endonuclease (iceA) HP1209 1 None None None 15645955 Pathogen - outer membrane protein (omp29) HP1342 1 None None None 15644640 Common panC pantoate--beta-alanine ligase HP0006 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 15645188 Pathogen - hypothetical protein HP0563 1 None None None 15645146 Pathogen - hypothetical protein HP0519 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15646087 Common - DNA helicase II (uvrD) HP1478 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15645154 Common - cag pathogenicity island protein (cag8) HP0528 8 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 15645352 Pathogen - hypothetical protein HP0732 1 None None None 15644854 Common - hypothetical protein HP0226 35 COG0730 COG0730, Predicted permeases General function prediction only 15645701 Common - bifunctional riboflavin kinase/FMN adenylyltransferase HP1087 208 COG0196 RibF, FAD synthase Coenzyme metabolism 15646109 Pathogen - hypothetical protein HP1500 1 None None None 15644862 Pathogen - hypothetical protein HP0234 2 None None None 15645483 Common - hypothetical protein HP0864 7 None None None 15646171 Common - outer membrane protein HP1564 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 15644770 Common - L-lactate permease (lctP) HP0140 104 COG1620 LldP, L-lactate permease Energy production and conversion 15645472 Common - ABC transporter, ATP-binding protein (yheS) HP0853 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 15645602 Pathogen - hypothetical protein HP0987 1 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 15645863 Common aroE shikimate 5-dehydrogenase HP1249 220 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 15645226 Common - flagellin A HP0601 132 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15644906 Common - guanosine pentaphosphate phosphohydrolase (gppA) HP0278 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 15644830 Common - fatty acid/phospholipid synthesis protein HP0201 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 15645895 Common - anthranilate synthase component I HP1282 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15644900 Common - hypothetical protein HP0272 4 None None None 15645383 Common - hypothetical protein HP0764 4 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 15644767 Common - hypothetical protein HP0137 54 COG1556 COG1556, Uncharacterized conserved protein Function unknown 15644693 Pathogen - hypothetical protein HP0063 1 None None None 15646198 Common fliP flagellar biosynthesis protein HP0684 10 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 15646126 Common - type IIS restriction enzyme R and M protein (ECO57IR) HP1517 68 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 15645872 Common - conserved hypothetical mitochondrial protein 4 HP1258 7 COG1714 COG1714, Predicted membrane protein/domain Function unknown 15644816 Common - hypothetical protein HP0187 3 None None None 15644722 Common - type II restriction enzyme M protein (hsdM) HP0092 94 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15645045 Common metG methionyl-tRNA synthetase HP0417 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15646123 Common nusA transcription elongation factor NusA HP1514 216 COG0195 NusA, Transcription elongation factor Transcription 15644997 Common - hypothetical protein HP0369 3 None None None 15646013 Common - type I restriction enzyme M protein (hsdM) HP1403 154 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15645842 Common - dinucleoside polyphosphate hydrolase HP1228 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15645926 Common rpsC 30S ribosomal protein S3 HP1313 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 15645616 Pathogen - hypothetical protein HP1001 1 None None None 15645771 Pathogen - outer membrane protein (omp26) HP1157 1 None None None 15645786 Common - glutamine ABC transporter, periplasmic glutamine-binding protein (glnH) HP1172 156 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15645069 Common - VirB4 homolog HP0441 57 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 15645368 Common - cell division membrane protein (ftsX) HP0749 7 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 15645314 Common - 3-oxoadipate coA-transferase subunit A (yxjD) HP0691 98 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 15645756 Common - hypothetical protein HP1142 35 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 15645502 Common - hypothetical protein HP0884 4 None None None 15645810 Common - 30S ribosomal protein S7 HP1196 232 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 15645093 Common - hypothetical protein HP0465 14 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15645316 Common - hypothetical protein HP0693 42 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 15645968 Common - quinolinate synthetase HP1356 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 15644986 Common - hypothetical protein HP0358 6 None None None 15645562 Common - hypothetical protein HP0946 70 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 15645737 Common - peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase (slyD) HP1123 134 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 15646011 Common - hypothetical protein HP1401 100 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 15646100 Common - phosphate permease HP1491 153 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 15645206 Common - dihydroorotase HP0581 87 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 15645919 Common rpsN 30S ribosomal protein S14 HP1306 192 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 15644720 Common - acyl-carrier-protein S-malonyltransferase HP0090 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 15645360 Common - UDP-MurNac-pentapeptide presynthetase (murF) HP0740 196 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 15644727 Pathogen - hypothetical protein HP0097 1 None None None 15645004 Common hemH ferrochelatase HP0376 161 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 15646062 Pathogen - hypothetical protein HP1453 1 None None None 15645908 Common - 30S ribosomal protein S11 HP1295 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 15645071 Pathogen - hypothetical protein HP0443 1 None None None 15646161 Common rpsB 30S ribosomal protein S2 HP1554 223 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 15645333 Pathogen - hypothetical protein HP0710 1 None None None 15646082 Common - hypothetical protein HP1473 7 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 15644708 Pathogen - hypothetical protein HP0078 1 None None None 15645198 Common - hypothetical protein HP0573 4 None None None 15645879 Common - hypothetical protein HP1265 4 None None None 15644881 Pathogen - hypothetical protein HP0253 1 None None None 15646073 Common - conserved hypothetical secreted protein HP1464 60 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 15645436 Pathogen - hypothetical protein HP0817 1 None None None 15645057 Pathogen - hypothetical protein HP0429 1 None None None 15645344 Common - L-asparaginase II (ansB) HP0723 133 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 15645634 Common ispDF bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein HP1020 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 15644677 Pathogen - hypothetical protein HP0046 1 None None None 15645569 Pathogen - hypothetical protein HP0953 1 None None None 15645708 Common - hypothetical protein HP1094 3 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 15645779 Common - tetracycline resistance protein tetA(P), putative HP1165 6 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15646004 Common - hypothetical protein HP1394 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 15645232 Common - acriflavine resistance protein (acrB) HP0607 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 15644886 Common - hypothetical protein HP0258 187 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15645323 Common - diacylglycerol kinase (dgkA) HP0700 98 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 15645176 Common rpmE 50S ribosomal protein L31 HP0551 171 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 15645764 Common - hypothetical protein HP1150 7 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 15645212 Common - aminodeoxychorismate lyase (pabC) HP0587 184 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 15644861 Common - hypothetical protein HP0233 52 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 15645673 Common ruvB Holliday junction DNA helicase B HP1059 217 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 15645832 Common - glycinamide ribonucleotide synthetase (purD) HP1218 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 15645289 Common - coproporphyrinogen III oxidase HP0665 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15646204 Common fbcH ubiquinol cytochrome c oxidoreductase, cytochrome c1 HP1538 9 COG2857 CYT1, Cytochrome c1 Energy production and conversion 15645028 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase HP0400 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 15645606 Pathogen - hypothetical protein HP0991 1 None None None 15645062 Pathogen - hypothetical protein HP0434 1 None None None 15645297 Pathogen - hypothetical protein HP0673 1 None None None 15644937 Common - hypothetical protein HP0309 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15645037 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein HP0409 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 15645540 Common - 4-oxalocrotonate tautomerase (dmpI) HP0924 34 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 15645993 Common - restriction modification system S subunit HP1383 12 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 15646028 Common fliQ flagellar biosynthesis protein FliQ HP1419 77 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 15645077 Pathogen - hypothetical protein HP0449 1 None None None 15644686 Common - proline permease (putP) HP0055 179 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 15644941 Common - nitrite extrusion protein (narK) HP0313 76 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15645460 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase HP0841 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 15645423 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein HP0804 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 15645490 Common - CDP-diacylglycerol pyrophosphatase HP0871 18 COG2134 Cdh, CDP-diacylglycerol pyrophosphatase Lipid metabolism 15645214 Common oorA 2-oxoglutarate-acceptor oxidoreductase subunit OorA HP0589 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15644931 Common obgE GTPase ObgE HP0303 249 COG0536 Obg, Predicted GTPase General function prediction only 15644966 Pathogen - hypothetical protein HP0338 1 None None None 15645030 Common pheT phenylalanyl-tRNA synthetase subunit beta HP0402 231 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 15644950 Common - poly E-rich protein HP0322 22 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 15645405 Common secA preprotein translocase subunit SecA HP0786 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 15645115 Pathogen - hypothetical protein HP0488 4 None None None 15644656 Pathogen - hypothetical protein HP0023 1 None None None 15645168 Pathogen - cag pathogenicity island protein (cag21) HP0542 1 None None None 15646152 Common - folylpolyglutamate synthase (folC) HP1545 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 15645806 Pathogen - secreted protein involved in flagellar motility HP1192 1 None None None 15644665 Common - hypothetical protein HP0032 115 COG2127 COG2127, Uncharacterized conserved protein Function unknown 15645694 Common - hypothetical protein HP1080 25 COG1787 COG1787, Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes Defense mechanisms 15646018 Pathogen - hypothetical protein HP1408 2 None None None 15644957 Common - NH(3)-dependent NAD+ synthetase (nadE) HP0329 223 COG0171 NadE, NAD synthase Coenzyme metabolism 15645513 Pathogen - hypothetical protein HP0895 1 None None None 15645134 Common - hypothetical protein HP0507 18 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 15645357 Common - hypothetical protein HP0737 47 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 15646037 Common - hypothetical protein HP1428 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 15646185 Common - LPS biosynthesis protein HP1578 4 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 15645593 Common - cell division protein (ftsA) protein HP0978 175 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 15646159 Common - Na+/H+ antiporter (nhaA) HP1552 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 15645931 Common rplD 50S ribosomal protein L4 HP1318 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 15644771 Common - L-lactate permease (lctP) HP0141 103 COG1620 LldP, L-lactate permease Energy production and conversion 15645103 Common - molybdenum ABC transporter, ATP-binding protein (modD) HP0475 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 161353440 Common - S-ribosylhomocysteinase HP0105 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 15644929 Common - dipeptide ABC transporter, ATP-binding protein (dppD) HP0301 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 15644919 Common - hypothetical protein HP0291 32 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 15646131 Common - DNA recombinase (recG) HP1523 212 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 15644864 Common - hypothetical protein HP0236 7 None None None 15645034 Common - hypothetical protein HP0406 4 None None None 15645961 Common - 1-acyl-glycerol-3-phosphate acyltransferase (plsC) HP1348 139 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 15645658 Common - hypothetical protein HP1044 86 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 15645668 Common - hypothetical protein HP1054 13 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15645118 Common rpmB 50S ribosomal protein L28 HP0491 7 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 15644842 Common - sodium-dependent transporter (huNaDC-1) HP0214 125 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 15645661 Common rbfA ribosome-binding factor A HP1047 7 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 15645489 Common flgE flagellar hook protein FlgE HP0870 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 15645614 Pathogen - hypothetical protein HP0999 1 None None None 15645236 Pathogen - hypothetical protein HP0611 1 None None None 15645581 Common - hypothetical protein HP0965 11 COG0486 ThdF, Predicted GTPase General function prediction only 15645395 Common - DNA-directed RNA polymerase subunit omega HP0776 6 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 15645644 Common - flagellar motor switch protein FliY HP1030 118 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 15645857 Pathogen - outer membrane protein (omp28) HP1243 1 None None None 15645054 Common - hypothetical protein HP0426 75 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15645121 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase HP0494 204 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 15644835 Pathogen - hypothetical protein HP0206 1 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 15645464 Common - hydroxyethylthiazole kinase HP0845 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 15646192 Common flgG flagellar basal body rod protein FlgG HP1585 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15644853 Pathogen - hypothetical protein HP0225 1 None None None 15645839 Common - hypothetical protein HP1225 180 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 15645976 Common - signal-transducing protein, histidine kinase HP1364 45 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 15644953 Common flgH flagellar basal body L-ring protein HP0325 98 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 15645538 Common - toxin-like outer membrane protein HP0922 14 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 15646007 Common - hypothetical protein HP1397 47 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15645435 Common motB flagellar motor protein MotB HP0816 118 COG1360 MotB, Flagellar motor protein Cell motility and secretion 15644705 Common - urease protein (ureC) HP0075 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15645014 Pathogen - hypothetical protein HP0386 1 None None None 15645651 Common - hypothetical protein HP1037 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 15646042 Common - hypothetical protein HP1433 3 None None None 15646098 Common - lipase-like protein HP1489 26 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15646116 Common - conserved hypothetical ATP-binding protein HP1507 51 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 15645676 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase HP1062 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 15645066 Common - IS605 transposase (tnpB) HP0438 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15644804 Common - cell binding factor 2 HP0175 149 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15645261 Pathogen - hypothetical protein HP0637 1 None None None 15645944 Common - hypothetical protein HP1331 100 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 15644781 Common - hypothetical protein HP0152 37 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 15645221 Pathogen - tumor necrosis factor alpha-inducing protein HP0596 1 None None None 15645500 Pathogen - hypothetical protein HP0881 1 None None None 15645523 Common flgD flagellar basal body rod modification protein HP0907 55 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 15645985 Common - UDP-N-acetylglucosamine acyltransferase HP1375 159 COG1043 LpxA, Acyl- acyl carrier protein 15646107 Common - hypothetical protein HP1498 14 COG0795 COG0795, Predicted permeases General function prediction only 15645575 Common - hypothetical protein HP0959 74 COG0327 COG0327, Uncharacterized conserved protein Function unknown 15645903 Common - nicotinamide mononucleotide transporter (pnuC) HP1290 28 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 15645795 Common - multidrug-efflux transporter HP1181 162 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15645443 Common - thioredoxin (trxA) HP0824 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15645381 Pathogen - hypothetical protein HP0762 1 None None None 15645671 Pathogen - hypothetical protein HP1057 1 None None None 15645861 Common - DNA polymerase III subunit delta HP1247 7 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 15645474 Common - alginate O-acetylation protein (algI) HP0855 87 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 15645372 Common fliS flagellar protein FliS HP0753 85 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 15645728 Common - excinuclease ABC subunit B HP1114 226 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 15645350 Pathogen - hypothetical protein HP0730 2 None None None 15645276 Common - phosphoserine phosphatase (serB) HP0652 149 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 15645400 Common - hypothetical protein HP0781 6 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 15644691 Pathogen - hypothetical protein HP0061 1 None None None 15645828 Common - hypothetical protein HP1214 53 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 15646022 Pathogen - hypothetical protein HP1412 1 None None None 15645893 Common - bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase HP1279 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 15645043 Common - hypothetical protein HP0415 216 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15645138 Pathogen - hypothetical protein HP0511 1 None None None 15645949 Common - hypothetical protein HP1336 3 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15645042 Common - IS200 insertion sequence from SARA17 HP0414 76 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15645870 Common frr ribosome recycling factor HP1256 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 15644769 Common - conserved hypothetical secreted protein HP0139 154 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 15644679 Common - transcriptional regulator (hypF) HP0048 110 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15644788 Common - lipopolysaccharide 1,2-glucosyltransferase (rfaJ) HP0159 22 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 15645300 Common - methylated-DNA--protein-cysteine methyltransferase (dat1) HP0676 218 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 15644751 Common - phosphoenolpyruvate synthase HP0121 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 15645628 Common - 7-alpha-hydroxysteroid dehydrogenase HP1014 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15645840 Common - coproporphyrinogen III oxidase HP1226 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 15645953 Common - biopolymer transport protein (exbD) HP1340 100 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 15645621 Common - conjugal transfer protein (traG) HP1006 63 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 15645025 Common - phosphoglycerate dehydrogenase (serA) HP0397 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 15645486 Common lpxB lipid-A-disaccharide synthase HP0867 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 15644978 Pathogen - hypothetical protein HP0350 1 None None None 15645821 Common - hypothetical protein HP1207 9 COG0546 Gph, Predicted phosphatases General function prediction only 15646146 Common - ubiquinol cytochrome c oxidoreductase, cytochrome b subunit (fbcH) HP1539 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 15645277 Common - nonheme iron-containing ferritin (pfr) HP0653 83 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 15644659 Common gltA type II citrate synthase HP0026 194 COG0372 GltA, Citrate synthase Energy production and conversion 15645686 Common - copper-transporting ATPase, P-type (copA) HP1072 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15644825 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase HP0196 169 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 15644646 Common - hypothetical protein HP0013 27 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 15645128 Common gyrB DNA gyrase subunit B HP0501 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 15644711 Pathogen - hypothetical protein HP0081 1 None None None 15646102 Common - hypothetical protein HP1493 7 None None None 15645182 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha HP0557 185 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 15645152 Pathogen - cag pathogenicity island protein (cag6) HP0526 1 None None None 15645388 Common - molybdopterin-guanine dinucleotide biosynthesis protein A HP0769 28 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 15645148 Pathogen - cag pathogenicity island protein (cag3) HP0522 1 None None None 15644649 Pathogen - hypothetical protein HP0016 1 None None None 15644741 Common - heat-inducible transcription repressor HP0111 69 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 15645346 Pathogen - hypothetical protein HP0726 1 None None None 15645196 Common - hypothetical protein HP0571 27 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15645877 Common - NADH dehydrogenase subunit D HP1263 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 15646051 Common - carbon storage regulator HP1442 43 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 15645725 Common - ferrodoxin oxidoreductase beta subunit HP1111 127 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 15645688 Pathogen - hypothetical protein HP1074 1 None None None 15645636 Common - hypothetical protein HP1022 17 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 15645334 Common - hypothetical protein HP0711 11 COG4940 ComGF, Competence protein ComGF Intracellular trafficking and secretion 15646071 Pathogen - secreted protein involved in flagellar motility HP1462 2 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 15645142 Common - ATP-dependent protease peptidase subunit HP0515 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 15645059 Common - protein phosphatase 2C homolog (ptc1) HP0431 3 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 15645488 Common hypA hydrogenase nickel incorporation protein HP0869 41 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 15645742 Pathogen - hypothetical protein HP1128 1 None None None 15645730 Pathogen - hypothetical protein HP1116 4 None None None 15646067 Common - thioredoxin HP1458 227 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15644999 Common - biotin carboxyl carrier protein (fabE) HP0371 167 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 48734589 Common ackA acetate kinase HP0903m 162 COG0282 ackA, Acetate kinase Energy production and conversion 15644667 Common - aspartate alpha-decarboxylase HP0034 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 15644888 Common - adenine specific DNA methyltransferase (mod) HP0260 83 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 15645230 Common - hypothetical protein HP0605 13 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15645995 Common - fructose-1,6-bisphosphatase HP1385 107 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 15645321 Pathogen - hypothetical protein HP0698 1 None None None 15645052 Pathogen - hypothetical protein HP0424 1 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 15646182 Common - ABC transporter, putative HP1575 86 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 15645555 Common - amino acid ABC transporter, permease protein (yckJ) HP0939 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15645564 Common - hypothetical protein HP0948 7 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 15645073 Pathogen - hypothetical protein HP0445 1 None None None 15645868 Common - biotin synthesis protein (bioC) HP1254 17 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15644814 Pathogen - hypothetical protein HP0185 1 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 15644876 Common - hypothetical protein HP0248 34 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 15645558 Common - D-alanine glycine permease (dagA) HP0942 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 15645933 Common rpsJ 30S ribosomal protein S10 HP1320 245 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 15645784 Common - glutamine ABC transporter, permease protein (glnP) HP1170 157 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15644798 Common - collagenase (prtC) HP0169 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 15645906 Common - DNA-directed RNA polymerase subunit alpha HP1293 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 15645753 Common - SpoOJ regulator (soj) HP1139 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15645804 Common hisS histidyl-tRNA synthetase HP1190 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15646089 Common - seryl-tRNA synthetase HP1480 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 15644933 Common - hypothetical protein HP0305 8 None None None 15645362 Common - ribose-phosphate pyrophosphokinase HP0742 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 15645286 Common rnc ribonuclease III HP0662 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 15645175 Common rho transcription termination factor Rho HP0550 209 COG1158 Rho, Transcription termination factor Transcription 15645719 Common - LPS biosynthesis protein HP1105 9 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 15645106 Common - adenine specific DNA methyltransferase (VSPIM) HP0478 11 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 15645166 Pathogen - cag pathogenicity island protein (cag19) HP0540 1 None None None 15646084 Common coaD phosphopantetheine adenylyltransferase HP1475 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 15645848 Common - hypothetical protein HP1234 95 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 15645105 Pathogen - outer membrane protein (omp12) HP0477 1 None None None 15644917 Common - toxin-like outer membrane protein HP0289 35 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 15645595 Common - conserved hypothetical secreted protein HP0980 178 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 15645850 Common - hypothetical protein HP1236 8 COG2952 COG2952, Uncharacterized protein conserved in bacteria Function unknown 15645453 Common engA GTP-binding protein EngA HP0834 235 COG1160 COG1160, Predicted GTPases General function prediction only 15644943 Common - virulence associated protein D (vapD) HP0315 6 COG3309 VapD, Uncharacterized virulence-associated protein D Function unknown 15644904 Common - hypothetical protein HP0276 6 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 15645241 Common - chemotaxis protein (cheV) HP0616 135 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15645683 Common - cell division protein (ftsH) HP1069 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15645386 Pathogen - hypothetical protein HP0767 1 None None None 15644989 Common truA tRNA pseudouridine synthase A HP0361 232 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 15646049 Pathogen - hypothetical protein HP1440 1 None None None 15645817 Common nusG transcription antitermination protein NusG HP1203 215 COG0250 NusG, Transcription antiterminator Transcription 15645355 Common - xanthine guanine phosphoribosyl transferase (gpt) HP0735 34 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 15646035 Pathogen - hypothetical protein HP1426 1 None None None 15645036 Pathogen - hypothetical protein HP0408 1 None None None 15645731 Common - conserved hypothetical secreted protein HP1117 107 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15645158 Common - cag pathogenicity island protein (cag12) HP0532 2 None None None 15644968 Pathogen - hypothetical protein HP0340 1 None None None 15645426 Common - iron(III) dicitrate transport protein (fecA) HP0807 101 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 15645978 Pathogen - type IIS restriction enzyme R protein (MBOIIR) HP1366 1 None None None 15645830 Common - conserved hypothetical secreted protein HP1216 111 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 15645646 Common fliA flagellar biosynthesis sigma factor HP1032 132 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 15645287 Common - chorismate synthase HP0663 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 15645714 Common - phosphogluconate dehydratase HP1100 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 15645299 Common - integrase/recombinase (xerC) HP0675 216 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15645465 Common - type I restriction enzyme R protein (hsdR) HP0846 139 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 15645204 Pathogen - hypothetical protein HP0579 1 None None None 15644984 Common - hypothetical protein HP0356 4 None None None 15645915 Common rpsE 30S ribosomal protein S5 HP1302 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 15644776 Common - cytochrome c oxidase, diheme subunit, membrane-bound (fixP) HP0147 66 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 15645444 Common - thioredoxin reductase (trxB) HP0825 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15645023 Common - hypothetical protein HP0395 195 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 15645180 Common - hypothetical protein HP0555 6 None None None 15645951 Common - nickel responsive regulator HP1338 65 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 15646141 Common thyX FAD-dependent thymidylate synthase HP1533 35 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 15645721 Pathogen - outer membrane protein (omp23) HP1107 1 None None None 15645867 Common - tryptophanyl-tRNA synthetase HP1253 237 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645913 Common secY preprotein translocase subunit SecY HP1300 244 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 15644647 Common - hypothetical protein HP0014 14 None None None 15644976 Common - single-stranded-DNA-specific exonuclease (recJ) HP0348 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15646077 Common - branched-chain amino acid aminotransferase HP1468 206 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 15646193 Pathogen - hypothetical protein HP1586 1 None None None 15644858 Common - 3-deoxy-manno-octulosonate cytidylyltransferase HP0230 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 15646023 Common - 7-cyano-7-deazaguanine reductase HP1413 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 15645497 Pathogen - hypothetical protein HP0878 1 None None None 15645777 Common - hypothetical protein HP1163 5 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 15645977 Common - response regulator HP1365 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15645588 Common - hypothetical protein HP0973 3 None None None 15645150 Common - cag pathogenicity island protein (cag5) HP0524 59 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 15644823 Common tpiA triosephosphate isomerase HP0194 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 15645313 Common - acetyl coenzyme A acetyltransferase (thiolase) (fadA) HP0690 168 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 15645194 Common - translation-associated GTPase HP0569 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 15644819 Common - conserved hypothetical secreted protein HP0190 124 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15645899 Common - conserved hypothetical secreted protein HP1286 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 15644848 Common - cysteine desulfurase HP0220 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 15645218 Common - adenine specific DNA methyltransferase (mod) HP0593 93 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 15644635 Common nusB transcription antitermination protein NusB HP0001 177 COG0781 NusB, Transcription termination factor Transcription 15645155 Pathogen - cag pathogenicity island protein (cag9) HP0529 1 None None None 15644840 Common - succinyl-diaminopimelate desuccinylase HP0212 191 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 15646003 Common - DNA repair protein (recN) HP1393 169 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 15644763 Common - serine transporter (sdaC) HP0133 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 15645393 Common - tyrosyl-tRNA synthetase HP0774 241 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645667 Common minC septum formation inhibitor HP1053 5 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 15645387 Common moaA molybdenum cofactor biosynthesis protein A HP0768 204 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15646122 Common - selenocysteine synthase HP1513 64 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 15645136 Common - glycolate oxidase subunit (glcD) HP0509 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15644666 Common - ATP-dependent C1p protease (clpA) HP0033 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15644902 Common - hypothetical protein HP0274 19 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 15645693 Common - hypothetical protein HP1079 10 COG1106 COG1106, Predicted ATPases General function prediction only 15645413 Common clpP ATP-dependent Clp protease proteolytic subunit HP0794 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 15644939 Common - hypothetical protein HP0311 4 None None None 15645476 Common - phosphoheptose isomerase (gmhA) HP0857 124 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 15646009 Common - arginase (rocF) HP1399 59 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 15645760 Pathogen - hypothetical protein HP1146 1 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15644812 Common glyA serine hydroxymethyltransferase HP0183 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 15645559 Common - D-amino acid dehydrogenase (dadA) HP0943 112 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 15644725 Common - hypothetical protein HP0095 2 None None None 15645656 Common - hypothetical protein HP1042 10 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 15645041 Common - transposase-like protein, PS3IS HP0413 43 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15645012 Pathogen - hypothetical protein HP0384 1 None None None 15645972 Common ubiA prenyltransferase HP1360 184 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 15644783 Common eno phosphopyruvate hydratase HP0154 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 15645247 Common murC UDP-N-acetylmuramate--L-alanine ligase HP0623 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 15645577 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase HP0961 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 15644808 Common - ABC transporter, ATP-binding protein HP0179 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15645924 Common rpmC 50S ribosomal protein L29 HP1311 3 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 15646093 Common - hypothetical protein HP1484 95 COG1981 COG1981, Predicted membrane protein Function unknown 15645514 Pathogen - outer membrane protein (omp19) HP0896 1 None None None 15644802 Common fliR flagellar biosynthesis protein FliR HP0173 120 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 15644650 Common - virB4 homolog (virB4) HP0017 59 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 15645846 Common - dihydropteroate synthase (folP) HP1232 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 15645901 Pathogen - hypothetical protein HP1288 1 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 15645022 Common - hypothetical protein HP0394 14 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 15644899 Common - hypothetical protein HP0271 3 None None None 15645797 Common - NA+/H+ antiporter (napA) HP1183 104 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15644738 Pathogen - hypothetical protein HP0108 2 None None None 15645309 Common - iron(III) dicitrate transport protein (fecA) HP0686 70 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 15644892 Common - ATP-dependent protease binding subunit (clpB) HP0264 234 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 15645123 Common - hypothetical protein HP0496 105 COG0824 FcbC, Predicted thioesterase General function prediction only 15644871 Common - neutrophil activating protein (napA) (bacterioferritin) HP0243 130 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 15644713 Common rpsI 30S ribosomal protein S9 HP0083 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 15645264 Common - poly(A) polymerase (papS) HP0640 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 15645420 Common - molybdopterin converting factor, subunit 1 (moaD) HP0801 7 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 15646154 Common leuS leucyl-tRNA synthetase HP1547 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645991 Pathogen - hypothetical protein HP1381 1 None None None 15645929 Common rplB 50S ribosomal protein L2 HP1316 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 15645529 Pathogen - outer membrane protein (omp21) HP0913 1 None None None 15646048 Pathogen - hypothetical protein HP1439 1 None None None 15645238 Common - ABC transporter, ATP-binding protein HP0613 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15645111 Common - hypothetical protein HP0484 2 None None None 15645930 Common rplW 50S ribosomal protein L23 HP1317 65 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 15645637 Pathogen - hypothetical protein HP1023 1 None None None 15645826 Common - F0F1 ATP synthase subunit C HP1212 9 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 15645048 Common - hypothetical protein HP0420 8 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 15646166 Common flgB flagellar basal body rod protein FlgB HP1559 91 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 15645537 Common - glyceraldehyde-3-phosphate dehydrogenase (gap) HP0921 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15645605 Pathogen - hypothetical protein HP0990 1 None None None 15645227 Common - endonuclease III HP0602 65 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 15644867 Common hemA glutamyl-tRNA reductase HP0239 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 15645112 Common - catalase-like protein HP0485 43 COG0753 KatE, Catalase Inorganic ion transport and metabolism 15646000 Pathogen - hypothetical protein HP1390 1 None None None 15645398 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase HP0779 221 COG1049 AcnB, Aconitase B Energy production and conversion 15644801 Common - molybdopterin biosynthesis protein (moeA) HP0172 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 15645406 Common - hypothetical protein HP0787 151 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 15645888 Common - paralysed flagella protein (pflA) HP1274 5 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 15644951 Common - membrane bound endonuclease (nuc) HP0323 51 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 15645980 Common - type IIS restriction enzyme M2 protein (mod) HP1368 106 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15645883 Common - NADH dehydrogenase subunit J HP1269 156 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 15645917 Common rplF 50S ribosomal protein L6 HP1304 228 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 15645374 Common - molybdopterin biosynthesis protein (moeB) HP0755 154 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 15645141 Common rplI 50S ribosomal protein L9 HP0514 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 15644946 Common - hypothetical protein HP0318 15 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 15645293 Common - hypothetical protein HP0669 35 COG4889 COG4889, Predicted helicase General function prediction only 15645376 Common - beta-alanine synthetase homolog HP0757 206 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15645173 Common - cag pathogenicity island protein (cag26) HP0547 11 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15645108 Common - GTP-binding protein, fusA-homolog (yihK) HP0480 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 15646201 Pathogen omp17 outer membrane protein HP0725 1 None None None 15645710 Common - IS605 transposase (tnpA) HP1096 60 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15646112 Common - cation-transporting ATPase, P-type (copA) HP1503 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 15645010 Common - zinc-metallo protease (YJR117W) HP0382 110 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15646206 Common - Component of conjugal plasmid transfer system HP0039m 10 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 15644911 Common aroB 3-dehydroquinate synthase HP0283 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 15645184 Common - acyl carrier protein (acpP) HP0559 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15646148 Common - transcription-repair coupling factor (trcF) HP1541 223 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 15645463 Common - thiamine biosynthesis protein (thi) HP0844 215 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 15645836 Common - D-lactate dehydrogenase (dld) HP1222 198 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 15645997 Common - DNA polymerase III subunit epsilon HP1387 139 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 15646135 Pathogen - hypothetical protein HP1527 1 None None None 15644935 Common - hypothetical protein HP0307 7 None None None 15645482 Common - hypothetical protein HP0863 7 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 15645548 Pathogen - hypothetical protein HP0932 1 None None None 15644698 Common - urease accessory protein (ureG) HP0068 153 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 15645084 Pathogen - hypothetical protein HP0456 1 None None None 15645696 Common - multidrug resistance protein (msbA) HP1082 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15646056 Common rpmH 50S ribosomal protein L34 HP1447 195 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 15645416 Pathogen - flagellar sheath adhesin hpaA HP0797 1 None None None 15646065 Pathogen - membrane-associated lipoprotein (lpp20) HP1456 1 None None None 15644787 Common - hypothetical protein HP0158 9 None None None 15645613 Common - IS605 transposase (tnpA) HP0998 60 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15644961 Common - DNA processing chain A (dprA) HP0333 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 15644993 Pathogen - hypothetical protein HP0365 1 None None None 15644779 Pathogen - hypothetical protein HP0150 1 None None None 15645691 Common - nickel transport protein (nixA) HP1077 38 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 15644689 Common - hypothetical protein HP0059 145 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 15644925 Common rpmA 50S ribosomal protein L27 HP0297 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 15645479 Common - hypothetical protein HP0860 132 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 15646177 Common - hypothetical protein HP1570 103 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 15646168 Common - iron(III) ABC transporter, periplasmic iron-binding protein (ceuE) HP1561 41 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15645445 Common - lipooligosaccharide 5G8 epitope biosynthesis-associated protein (lex2B) HP0826 14 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 15645751 Common - F0F1 ATP synthase subunit B' HP1137 7 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 15645007 Common - fucosyltransferase HP0379 11 None None None 15644920 Common - hypothetical protein HP0292 24 COG4866 COG4866, Uncharacterized conserved protein Function unknown 15644916 Common - hypothetical protein HP0288 6 None None None 15645648 Common - ATP-binding protein (ylxH) HP1034 239 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15645958 Common pgk phosphoglycerate kinase HP1345 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 15645665 Common - hypothetical protein HP1051 7 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 15644673 Common - trbI protein HP0042 55 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 15645712 Common - conserved hypothetical secreted protein HP1098 97 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15646086 Common flgA flagellar basal body P-ring biosynthesis protein FlgA HP1477 7 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 15645769 Common murG N-acetylglucosaminyl transferase HP1155 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 15645099 Common - glutathione-regulated potassium-efflux system protein (kefB) HP0471 206 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 15645163 Pathogen - cag pathogenicity island protein (cag16) HP0537 1 None None None 15645343 Common - hypothetical protein HP0721 2 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15645781 Pathogen - hypothetical protein HP1167 1 None None None 15644668 Common - hypothetical protein HP0035 29 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 15646180 Common - hypothetical protein HP1573 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 15645506 Common - iron(III) dicitrate ABC transporter, ATP-binding protein (fecE) HP0888 236 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 15645590 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C HP0975 15 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 15644874 Common flgI flagellar basal body P-ring protein HP0246 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 15645516 Common - hydrogenase expression/formation protein (hypD) HP0898 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15646053 Common smpB SsrA-binding protein HP1444 214 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 15646114 Common - riboflavin biosynthesis protein (ribG) HP1505 159 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 15645750 Common - F0F1 ATP synthase subunit B HP1136 7 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 15645170 Common - cag pathogenicity island protein (cag23) HP0544 65 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 15646060 Common - hypothetical protein HP1451 7 COG1847 Jag, Predicted RNA-binding protein General function prediction only 15645284 Common - hypothetical protein HP0660 7 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 15645626 Common - protease (pqqE) HP1012 195 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 15645733 Common flgK flagellar hook-associated protein FlgK HP1119 107 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 15645566 Common - acetyl-CoA carboxylase subunit beta HP0950 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 15646189 Common - pyridoxal phosphate biosynthetic protein PdxJ HP1582 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 15645544 Common folE GTP cyclohydrolase I HP0928 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 15645557 Common - alanine racemase, biosynthetic (alr) HP0941 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 15644748 Common - hypothetical protein HP0118 5 None None None 15645364 Common - hypothetical protein HP0745 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15645202 Common - methylene-tetrahydrofolate dehydrogenase (folD) HP0577 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 15645092 Common - type I restriction enzyme R protein (hsdR) HP0464 125 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 15645244 Common - inorganic pyrophosphatase HP0620 187 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 15645328 Common uvrA excinuclease ABC subunit A HP0705 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 15646021 Pathogen - hypothetical protein HP1411 1 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 15644882 Pathogen - outer membrane protein (omp8) HP0254 1 None None None 15645859 Common - single-strand DNA-binding protein HP1245 201 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 15645936 Common - ribonuclease HII (rnhB) HP1323 211 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 15645349 Pathogen - hypothetical protein HP0729 2 None None None 15645748 Common - F0F1 ATP synthase subunit alpha HP1134 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 15646015 Pathogen - hypothetical protein HP1405 1 None None None 15646175 Common - hypothetical protein HP1568 8 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 15644851 Common - DNA repair protein RadA HP0223 209 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 15645819 Common tuf elongation factor Tu HP1205 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 15645775 Common - flavodoxin FldA HP1161 64 COG0716 FldA, Flavodoxins Energy production and conversion 15645433 Common - thiamin biosynthesis protein (thiF) HP0814 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 15645451 Common speE spermidine synthase HP0832 27 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 15645726 Common - adenylosuccinate lyase HP1112 236 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 15645494 Common - catalase HP0875 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 15645706 Common - flagellar basal-body rod protein (flgG) HP1092 120 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 15645687 Pathogen - copper ion binding protein (copP) HP1073 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 15645055 Pathogen - hypothetical protein HP0427 2 None None None 15645744 Common - biopolymer transport protein (exbB) HP1130 33 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15645326 Common - response regulator HP0703 175 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 15645467 Common - type I restriction enzyme S protein (hsdS) HP0848 23 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 15644778 Common - hypothetical protein HP0149 3 None None None 15645448 Common - inositol-5-monophosphate dehydrogenase HP0829 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15646128 Common - hypothetical protein HP1519 4 None None None 15645224 Common - hemolysin secretion protein precursor (hylB) HP0599 127 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15645089 Pathogen - hypothetical protein HP0461 1 None None None 15645824 Common - serine acetyltransferase (cysE) HP1210 190 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 15645385 Pathogen - hypothetical protein HP0766 1 None None None 15644652 Common - chemotaxis protein (cheV) HP0019 146 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15645928 Common rpsS 30S ribosomal protein S19 HP1315 241 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 15646070 Common - cytochrome c551 peroxidase HP1461 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 15645143 Common hslU ATP-dependent protease ATP-binding subunit HP0516 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 15646173 Pathogen - hypothetical protein HP1566 1 None None None 15645478 Common - ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD) HP0859 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15645512 Common - hypothetical protein HP0894 34 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 15645415 Pathogen - outer membrane protein (omp18) HP0796 1 None None None 15646063 Pathogen - hypothetical protein HP1454 2 None None None 15644765 Pathogen - hypothetical protein HP0135 1 None None None 15644755 Common rpmI 50S ribosomal protein L35 HP0125 85 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 15645271 Pathogen - hypothetical protein HP0647 1 None None None 15644974 Common - hypothetical protein HP0346 4 None None None 15645209 Common - flagellar motor switch protein HP0584 115 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15644694 Pathogen - hypothetical protein HP0064 1 None None None 15645031 Common pheS phenylalanyl-tRNA synthetase subunit alpha HP0403 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 15644645 Common dnaG DNA primase HP0012 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 15644887 Common xseA exodeoxyribonuclease VII large subunit HP0259 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 15646143 Common - IS605 transposase (tnpA) HP1535 60 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15644661 Common - conserved hypothetical secreted protein HP0028 15 None None None 15645607 Pathogen - hypothetical protein HP0992 1 None None None 15645495 Common - iron-regulated outer membrane protein (frpB) HP0876 37 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15645311 Common - hypothetical protein HP0688 27 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 15645624 Common - polyphosphate kinase HP1010 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 15645240 Common ligA NAD-dependent DNA ligase LigA HP0615 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 15645422 Common - hypothetical protein HP0803 13 None None None 15644832 Pathogen - hypothetical protein HP0203 1 None None None 15645001 Pathogen - hypothetical protein HP0373 1 None None None 15645251 Pathogen - hypothetical protein HP0627 1 None None None 15646195 Common - hypothetical protein HP1588 9 COG4735 COG4735, Uncharacterized protein conserved in bacteria Function unknown 15644846 Common - hypothetical protein HP0218 49 COG1881 COG1881, Phospholipid-binding protein General function prediction only 15645897 Common - hypothetical protein HP1284 14 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15645531 Common - iron-regulated outer membrane protein (frpB) HP0915 23 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15644924 Common rplU 50S ribosomal protein L21 HP0296 167 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 15644732 Common - hypothetical protein HP0102 170 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 15646203 Common - hypothetical protein HP1353 19 COG4889 COG4889, Predicted helicase General function prediction only 15646156 Common secF preprotein translocase subunit SecF HP1549 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 15644979 Common fliF flagellar MS-ring protein HP0351 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 15645391 Common - N-acetylmuramoyl-L-alanine amidase (amiA) HP0772 176 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 15645932 Common rplC 50S ribosomal protein L3 HP1319 216 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 15645050 Common - arginine decarboxylase HP0422 140 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 15646210 Common secE preprotein translocase subunit SecE HP1203a 7 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 15645586 Pathogen - hypothetical protein HP0971 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15644637 Common - 2-dehydro-3-deoxyphosphooctonate aldolase HP0003 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 15645231 Common - membrane fusion protein (mtrC) HP0606 105 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15645356 Common - phosphoserine aminotransferase (serC) HP0736 154 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 15645584 Common - cation efflux system protein (czcA) HP0969 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 15645082 Common - hypothetical protein HP0454 4 None None None 15645654 Common rpsO 30S ribosomal protein S15 HP1040 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 15645718 Common - cinnamyl-alcohol dehydrogenase ELI3-2 (cad) HP1104 164 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 15645430 Common - hypothetical protein HP0811 3 None None None 15646164 Common fliE flagellar hook-basal body protein FliE HP1557 47 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 15645215 Common oorB 2-oxoglutarate-acceptor oxidoreductase subunit OorB HP0590 111 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 15645130 Pathogen - hypothetical protein HP0503 1 None None None 15644680 Common - hypothetical protein HP0049 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 15644869 Common - hypothetical protein HP0241 3 None None None 15644739 Common dnaK molecular chaperone DnaK HP0109 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15646196 Pathogen - hypothetical protein HP1590 1 COG4735 COG4735, Uncharacterized protein conserved in bacteria Function unknown 15645639 Common - putative heat shock protein (hspR) HP1025 82 COG0789 SoxR, Predicted transcriptional regulators Transcription 15645881 Common - NADH dehydrogenase subunit H HP1267 190 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 15644838 Common - heat shock protein 90 HP0210 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 15645672 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase HP1058 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 15645061 Pathogen - hypothetical protein HP0433 1 None None None 15644746 Common - DNA topoisomerase I HP0116 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15644785 Common - hypothetical protein HP0156 4 None None None 15644723 Common - hypothetical protein HP0093 18 None None None 15645439 Pathogen - hypothetical protein HP0820 1 None None None 15645922 Common rplN 50S ribosomal protein L14 HP1309 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 15645890 Pathogen - hypothetical protein HP1276 1 None None None 15645249 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase HP0625 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 15645078 Pathogen - hypothetical protein HP0450 1 None None None 15645254 Common - modulator of drug activity (mda66) HP0630 41 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 15645844 Common - hypothetical protein HP1230 7 None None None 15646046 Pathogen - hypothetical protein HP1437 2 None None None 15645599 Pathogen - hypothetical protein HP0984 1 None None None 15644701 Common - urease accessory protein (ureI) HP0071 16 None None None 15645534 Common - hypothetical protein HP0918 7 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 15645038 Pathogen - putative neuraminyllactose-binding hemagglutinin homolog (hpaA) HP0410 1 None None None 15645579 Common - hypothetical protein HP0963 4 COG1159 Era, GTPase General function prediction only 15645966 Common - putative adenine specific DNA methyltransferase HP1354 35 COG4889 COG4889, Predicted helicase General function prediction only 15645570 Common - oxygen-insensitive NAD(P)H nitroreductase HP0954 95 COG0778 NfnB, Nitroreductase Energy production and conversion 15645006 Common - cytochrome c biogenesis protein (ycf5) HP0378 101 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 15645266 Common - NAD(P)H-flavin oxidoreductase HP0642 70 COG0778 NfnB, Nitroreductase Energy production and conversion 15646091 Pathogen - hypothetical protein HP1482 1 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 15645773 Common - cell filamentation protein (fic) HP1159 29 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 15644890 Common - hypothetical protein HP0262 4 None None None 15644810 Common - hypothetical protein HP0181 12 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 15644909 Common tgt queuine tRNA-ribosyltransferase HP0281 230 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 15645791 Pathogen - outer membrane protein (omp27) HP1177 1 None None None 15645504 Common cysS cysteinyl-tRNA synthetase HP0886 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645429 Common - hypothetical protein HP0810 202 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 15645551 Common - hypothetical protein HP0935 15 COG0456 RimI, Acetyltransferases General function prediction only 15645785 Common - glutamine ABC transporter, ATP-binding protein (glnQ) HP1171 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 15645695 Pathogen - hypothetical protein HP1081 1 None None None 15645852 Common amiF formamidase HP1238 125 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15645068 Common - DNA topoisomerase I (topA) HP0440 246 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 15644873 Common - hypothetical protein HP0245 5 None None None 15645125 Common - sodium- and chloride-dependent transporter HP0498 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 15645527 Common - rep helicase, single-stranded DNA-dependent ATPase (rep) HP0911 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 15645979 Common - type IIS restriction enzyme M1 protein (mod) HP1367 110 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15645546 Common surE stationary phase survival protein SurE HP0930 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 15645999 Pathogen - hypothetical protein HP1389 1 None None None 15644773 Common - cytochrome c oxidase, heme b and copper-binding subunit, membrane-bound (fixN) HP0144 166 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 15644655 Common - lipid A phosphoethanolamine transferase HP0022 63 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15645418 Common mogA molybdenum cofactor biosynthesis protein HP0799 190 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 15645875 Common - NADH dehydrogenase subunit B HP1261 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 15645102 Common - molybdenum ABC transporter, permease protein (modB) HP0474 234 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 15645698 Common pyrB aspartate carbamoyltransferase catalytic subunit HP1084 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 15645371 Common fliD flagellar capping protein HP0752 85 COG1345 FliD, Flagellar capping protein Cell motility and secretion 15645133 Common - conserved hypothetical secreted protein HP0506 186 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15646030 Common - conjugative transfer regulon protein (trbB) HP1421 225 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 15646058 Common - hypothetical protein HP1449 58 COG0759 COG0759, Uncharacterized conserved protein Function unknown 15645447 Common - F0F1 ATP synthase subunit A HP0828 207 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 15644789 Common - conserved hypothetical secreted protein HP0160 81 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15645101 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein (modA) HP0473 119 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 15645611 Common - hypothetical protein HP0996 7 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 15644820 Common sdhB succinate dehydrogenase iron-sulfur subunit HP0191 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 15645378 Common - hypothetical protein HP0759 163 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15646133 Pathogen - hypothetical protein HP1525 1 None None None 15645766 Common - signal recognition particle protein (ffh) HP1152 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 15645396 Common pyrH uridylate kinase HP0777 236 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 15645854 Common maf Maf-like protein HP1240 24 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 15645159 Pathogen - hypothetical protein HP0533 1 None None None 15645457 Common - hypothetical protein HP0838 2 None None None 15645685 Common - phosphatidylserine synthase (pssA) HP1071 148 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 15645260 Pathogen - hypothetical protein HP0636 1 None None None 15645461 Common - hypothetical protein HP0842 3 None None None 15644948 Pathogen - conserved hypothetical secreted protein HP0320 2 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 15646026 Common - lipopolysaccharide 1,2-glucosyltransferase (rfaJ) HP1416 10 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 15645295 Pathogen - outer membrane protein (omp14) HP0671 1 None None None 15645641 Common - ferric uptake regulation protein (fur) HP1027 189 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 15646208 Common mod Adenine-specific DNA methylase HP1369m 130 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 15644914 Common - cell division protein (ftsH) HP0286 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 15646031 Common ileS isoleucyl-tRNA synthetase HP1422 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645161 Pathogen - cag pathogenicity island protein (cag14) HP0535 1 None None None 15645592 Common - conserved hypothetical secreted protein HP0977 73 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 15645018 Common - adhesin-thiol peroxidase (tagD) HP0390 97 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15646110 Pathogen - outer membrane protein (omp32) HP1501 1 None None None 15646088 Common - hypothetical protein HP1479 5 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 15644682 Common - cytosine specific DNA methyltransferase (DDEM) HP0051 132 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15644857 Pathogen - outer membrane protein (omp6) HP0229 1 None None None 15645450 Common coaE dephospho-CoA kinase HP0831 194 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 15645674 Common - sec-independent translocase HP1060 6 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 15646139 Common - hypothetical protein HP1531 2 None None None 15645492 Pathogen - hypothetical protein HP0873 1 None None None 15645187 Common rpsU 30S ribosomal protein S21 HP0562 9 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 15645834 Common - ABC transporter, ATP-binding protein (yhcG) HP1220 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 15644988 Common - UDP-glucose 4-epimerase HP0360 231 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 15645542 Common truD tRNA pseudouridine synthase D HP0926 86 COG0585 COG0585, Uncharacterized conserved protein Function unknown 15645229 Common hemE uroporphyrinogen decarboxylase HP0604 175 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 15644829 Common rpmF 50S ribosomal protein L32 HP0200 6 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 15644715 Pathogen - hypothetical protein HP0085 1 None None None 15645886 Common - NADH dehydrogenase subunit M HP1272 207 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 15645808 Pathogen - hypothetical protein HP1194 1 None None None 15645246 Common - hypothetical protein HP0622 3 None None None 15645090 Common - type I restriction enzyme S protein (hsdS) HP0462 59 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 15645704 Common - cell division protein (ftsK) HP1090 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15646017 Common - hypothetical protein HP1407 48 COG1295 Rbn, Predicted membrane protein Function unknown 15645812 Common - DNA-directed RNA polymerase subunit beta/beta' HP1198 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 15645989 Common - ATP-dependent protease (lon) HP1379 218 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 15645359 Common - 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase HP0739 18 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 15644663 Pathogen - hypothetical protein HP0030 1 None None None 15644995 Pathogen - hypothetical protein HP0367 1 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15645484 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase HP0865 174 COG0756 Dut, dUTPase Nucleotide transport and metabolism 15645331 Common - hypothetical protein HP0708 4 None None None 15644884 Pathogen - hypothetical protein HP0256 1 None None None 15644963 Pathogen - hypothetical protein HP0335 1 None None None 15645724 Common porA pyruvate flavodoxin oxidoreductase subunit alpha HP1110 111 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 15645938 Common fumC fumarate hydratase HP1325 234 COG0114 FumC, Fumarase Energy production and conversion 15645095 Common - hypothetical protein HP0467 2 None None None 15646075 Common - hypothetical protein HP1466 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 15644696 Common - conserved hypothetical ATP-binding protein HP0066 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 15644642 Pathogen - hypothetical protein HP0008 1 None None None 15645338 Common - hypothetical protein HP0716 7 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 15645207 Common - hypothetical protein HP0582 9 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 15645341 Pathogen - hypothetical protein HP0719 1 None None None 15645746 Common - F0F1 ATP synthase subunit beta HP1132 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 15645788 Common - glucose/galactose transporter (gluP) HP1174 48 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 15644927 Common - dipeptide ABC transporter, permease protein (dppB) HP0299 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15645568 Common - hypothetical protein HP0952 193 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 15645618 Common - hypothetical protein HP1003 4 None None None 15644639 Common - orotidine 5'-phosphate decarboxylase HP0005 163 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 15645179 Common - hypothetical protein HP0554 4 None None None 15646105 Common - 50S ribosomal protein L25/general stress protein Ctc HP1496 140 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 15646103 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase HP1494 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 15645982 Common - rod shape-determining protein (mreC) HP1372 8 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 15645801 Pathogen - hypothetical protein HP1187 1 None None None 15644684 Pathogen - hypothetical protein HP0053 1 None None None 15645767 Common valS valyl-tRNA synthetase HP1153 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645307 Common - UDP-N-acetylglucosamine pyrophosphorylase (glmU) HP0683 228 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 15644675 Common - GDP-D-mannose dehydratase (rfbD) HP0044 226 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 15644922 Common amiE acylamide amidohydrolase HP0294 143 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15645234 Common - hypothetical protein HP0609 10 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 15645865 Common - oligopeptide ABC transporter, permease protein (oppB) HP1251 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 15645097 Common - hypothetical protein HP0469 7 None None None 15646119 Common - hypothetical protein HP1510 8 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 15645318 Common - hydantoin utilization protein A (hyuA) HP0695 97 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15645192 Common - membrane protein HP0567 65 COG0628 PerM, Predicted permease General function prediction only 15644794 Common - hypothetical protein HP0165 2 None None None 15645366 Common trmB tRNA (guanine-N(7))-methyltransferase HP0747 175 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 15645757 Common - hypothetical protein HP1143 13 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 15645713 Common - 2-keto-3-deoxy-6-phosphogluconate aldolase (eda) HP1099 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 15645736 Pathogen - hypothetical protein HP1122 1 None None None 15645811 Common rpsL 30S ribosomal protein S12 HP1197 221 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 15644998 Common - biotin carboxylase HP0370 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 15645984 Common clpX ATP-dependent protease ATP-binding subunit HP1374 218 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 15644683 Pathogen - hypothetical protein HP0052 2 None None None 15645934 Common - conserved hypothetical ATP-binding protein HP1321 5 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 15644913 Common - hypothetical protein HP0285 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15645729 Common - hypothetical protein HP1115 7 None None None 15646162 Common tsf elongation factor Ts HP1555 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 15645183 Common - 3-oxoacyl-(acyl carrier protein) synthase II HP0558 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15645561 Pathogen - hypothetical protein HP0945 1 None None None 15645909 Common rpsM 30S ribosomal protein S13 HP1296 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 15645361 Common - hypothetical protein HP0741 99 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15645051 Pathogen - hypothetical protein HP0423 1 None None None 15644930 Common - dipeptide ABC transporter, ATP-binding protein (dppF) HP0302 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 15645805 Common - ADP-heptose-lps heptosyltransferase II (rfaF) HP1191 104 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15645615 Common - PARA protein HP1000 50 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15645755 Common fmt methionyl-tRNA formyltransferase HP1141 214 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 15644749 Pathogen - hypothetical protein HP0119 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 15645174 Common - glutamate racemase HP0549 166 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 15645965 Common - adenine specific DNA methyltransferase (HINFIM) HP1352 131 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15645754 Common - biotin--protein ligase HP1140 124 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 15645305 Pathogen - hypothetical protein HP0681 1 None None None 15645369 Common - hypothetical protein HP0750 71 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 15645098 Common - oligoendopeptidase F (pepF) HP0470 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 15645707 Pathogen - hypothetical protein HP1093 1 None None None 15645242 Common aspS aspartyl-tRNA synthetase HP0617 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15644676 Common - nodulation protein (nolK) HP0045 150 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15646019 Common - hypothetical protein HP1409 75 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15645317 Common - hypothetical protein HP0694 28 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 15645772 Common - pyrroline-5-carboxylate reductase HP1158 173 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 15645324 Common - DNA gyrase subunit A HP0701 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 15646010 Common - iron(III) dicitrate transport protein (fecA) HP1400 108 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 15645783 Common - glutamine ABC transporter, permease protein (glnP) HP1169 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 15645939 Common - hypothetical protein HP1326 5 None None None 15645822 Common - ulcer associated adenine specific DNA methyltransferase HP1208 19 COG3392 COG3392, Adenine-specific DNA methylase DNA replication, recombination, and repair 15645239 Pathogen - hypothetical protein HP0614 1 None None None 15644790 Pathogen - hypothetical protein HP0161 1 None None None 15645205 Common - hypothetical protein HP0580 8 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 15645960 Common - uracil-DNA glycosylase HP1347 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 15645473 Common - guanosine 5'-monophosphate oxidoreductase HP0854 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 15645298 Pathogen - hypothetical protein HP0674 1 None None None 15645332 Common - hypothetical protein HP0709 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 15645199 Common - ribose-5-phosphate isomerase B HP0574 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 15646074 Common - ABC transporter ATP-binding protein HP1465 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 15644707 Common prfA peptide chain release factor 1 HP0077 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 15644877 Pathogen - hypothetical protein HP0249 1 None None None 15644991 Common pcm protein-L-isoaspartate O-methyltransferase HP0363 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 15645354 Common - hypothetical protein HP0734 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15645058 Pathogen - hypothetical protein HP0430 1 None None None 15645437 Common - osmoprotection protein (proWX) HP0818 99 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 15644889 Pathogen - hypothetical protein HP0261 1 None None None 15645345 Common - anaerobic C4-dicarboxylate transporter HP0724 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 15645096 Common - hypothetical protein HP0468 3 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 15645335 Common - hypothetical protein HP0712 5 COG3177 COG3177, Uncharacterized conserved protein Function unknown 15645281 Common - processing protease (ymxG) HP0657 170 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 15646115 Common - glutamate permease (gltS) HP1506 54 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 15644797 Common - hypothetical protein HP0168 4 None None None 15645878 Common - hypothetical protein HP1264 6 None None None 15645211 Common - hypothetical protein HP0586 11 None None None 15646132 Pathogen - hypothetical protein HP1524 1 None None None 15644775 Common - cbb3-type cytochrome c oxidase subunit Q (CcoQ) HP0146 5 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 15645940 Common - hypothetical protein HP1327 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15644880 Pathogen - outer membrane protein (omp7) HP0252 1 None None None 15644662 Common - dethiobiotin synthetase (bioD) HP0029 113 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 15645074 Pathogen - hypothetical protein HP0446 1 None None None 15646027 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase HP1418 147 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 15645427 Common acpS 4'-phosphopantetheinyl transferase HP0808 119 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 15645994 Common - hypothetical protein HP1384 6 None None None 15646205 Common - hypothetical protein HP1589 9 COG4735 COG4735, Uncharacterized protein conserved in bacteria Function unknown 15646158 Common yajC preprotein translocase subunit YajC HP1551 66 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 15644827 Common - nucleoside diphosphate kinase (ndk) HP0198 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 15646174 Common - GTPase EngB HP1567 173 COG0218 COG0218, Predicted GTPase General function prediction only 15645864 Pathogen - hypothetical protein HP1250 1 None None None 15645135 Common - hypothetical protein HP0508 7 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 15645682 Common prmA ribosomal protein L11 methyltransferase HP1068 176 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 15646186 Pathogen - hypothetical protein HP1579 1 None None None 15644685 Common - adenine/cytosine DNA methyltransferase HP0054 85 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15644960 Common minE cell division topological specificity factor MinE HP0332 16 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 15645208 Pathogen - hypothetical protein HP0583 1 None None None 15646038 Common - polysialic acid capsule expression protein (kpsF) HP1429 149 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 15645213 Common oorD 2-oxoglutarate-acceptor oxidoreductase subunit OorD HP0588 62 COG1146 COG1146, Ferredoxin Energy production and conversion 15645652 Common - 3-dehydroquinate dehydratase HP1038 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 15644958 Common - ketol-acid reductoisomerase HP0330 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 15645833 Pathogen - hypothetical protein HP1219 1 None None None 15646061 Common trmE tRNA modification GTPase TrmE HP1452 225 COG0486 ThdF, Predicted GTPase General function prediction only 15645765 Common rpsP 30S ribosomal protein S16 HP1151 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 15645454 Common - histone-like DNA-binding protein HU (hup) HP0835 194 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 15645541 Common recR recombination protein RecR HP0925 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 15644944 Pathogen - hypothetical protein HP0316 1 None None None 15645643 Common - hypothetical protein HP1029 9 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 15644965 Pathogen - hypothetical protein HP0337 1 None None None 15646052 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase HP1443 18 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 15645219 Pathogen - hypothetical protein HP0594 2 None None None 15645594 Common - cell division protein FtsZ HP0979 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 15645262 Pathogen - outer membrane protein (omp13) HP0638 1 None None None 15645510 Common - hypothetical protein HP0892 34 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 15645572 Common - hypothetical protein HP0956 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15645524 Common flgE flagellar hook protein FlgE HP0908 124 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 15644791 Common - hypothetical protein HP0162 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 15646151 Common - toxR-activated gene (tagE) HP1544 186 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 15644896 Common - hypothetical protein HP0268 7 None None None 15645394 Common - penta-phosphate guanosine-3'-pyrophosphohydrolase (spoT) HP0775 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 15644780 Pathogen - hypothetical protein HP0151 1 None None None 15645574 Common - hypothetical protein HP0958 23 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 15645114 Pathogen - hypothetical protein HP0487 1 None None None 15645843 Common - aspartate kinase HP1229 237 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 15645669 Pathogen - hypothetical protein HP1055 1 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 15645659 Common - acetyl-CoA synthetase HP1045 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 15644671 Common - hypothetical protein HP0038 3 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 15645029 Common - 3-phosphoshikimate 1-carboxyvinyltransferase HP0401 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 15645220 Common - hypothetical protein HP0595 6 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 15646117 Common - ferrodoxin-like protein HP1508 86 COG0348 NapH, Polyferredoxin Energy production and conversion 15645267 Common gltX glutamyl-tRNA synthetase HP0643 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15646097 Common - conserved hypothetical secreted protein HP1488 106 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 15645167 Pathogen - cag pathogenicity island protein (cag20) HP0541 1 None None None 15645015 Common - primosome assembly protein PriA HP0387 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 15645622 Common - IS200 insertion sequence from SARA17 HP1008 76 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15645466 Pathogen - hypothetical protein HP0847 1 None None None 15644806 Common - elongation factor P HP0177 218 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 15645943 Common - hypothetical protein HP1330 14 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 15645292 Common - hypothetical protein HP0668 63 COG4889 COG4889, Predicted helicase General function prediction only 15644834 Common - hypothetical protein HP0205 11 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 15645288 Common - hypothetical protein HP0664 4 None None None 15644717 Common - hypothetical protein HP0087 23 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 15646184 Common - ABC transporter, permease protein (yaeE) HP1577 88 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 15645596 Common - exonuclease VII-like protein (xseA) HP0981 102 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 15646079 Common - DNA polymerase I (polA) HP1470 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 15645411 Common - sigma-54 interacting protein HP0792 187 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 15645973 Common - competence locus E (comE3) HP1361 7 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 15645716 Common - glucose-6-phosphate 1-dehydrogenase (devB) HP1102 109 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 15646137 Common dnaA chromosomal replication initiation protein HP1529 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 15645373 Pathogen - hypothetical protein HP0754 1 None None None 15644657 Pathogen - hypothetical protein HP0024 1 None None None 15646043 Common - formyltetrahydrofolate hydrolase (purU) HP1434 219 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 15645598 Common - hypothetical protein HP0983 177 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15645533 Pathogen - hypothetical protein HP0917 1 None None None 15645891 Common trpA tryptophan synthase subunit alpha HP1277 215 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 15644845 Pathogen - hypothetical protein HP0217 2 None None None 15644761 Pathogen - hypothetical protein HP0131 1 None None None 15645814 Common rplJ 50S ribosomal protein L10 HP1200 190 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 15645962 Common - hypothetical protein HP1349 7 None None None 15645920 Common rplE 50S ribosomal protein L5 HP1307 247 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 15645632 Pathogen - hypothetical protein HP1018 1 None None None 15645759 Pathogen - hypothetical protein HP1145 1 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15645404 Common lolA outer-membrane lipoprotein carrier protein HP0785 14 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 15644860 Common - hypothetical protein HP0232 6 None None None 15645455 Pathogen - hypothetical protein HP0836 1 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 15644744 Common - hypothetical protein HP0114 15 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 15645063 Common - hypothetical protein HP0435 12 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 15645662 Common infB translation initiation factor IF-2 HP1048 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 15645582 Common - hypothetical protein HP0966 21 None None None 15645127 Common - DNA polymerase III subunit beta HP0500 212 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 15645223 Common - 8-amino-7-oxononanoate synthase (bioF) HP0598 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 15644643 Common groEL chaperonin GroEL HP0010 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 15645609 Common - hypothetical protein HP0994 12 None None None 15645856 Common - hypothetical protein HP1242 28 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 15645020 Common - histidine kinase (cheA) HP0392 223 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 15645910 Common rpmJ 50S ribosomal protein L36 HP1297 7 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 15645145 Common - conserved hypothetical secreted protein HP0518 23 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 15645151 Common - virB11 homolog HP0525 210 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 15644855 Pathogen - outer membrane protein (omp5) HP0227 1 None None None 15645720 Pathogen - hypothetical protein HP1106 1 None None None 15645702 Common - transketolase HP1088 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 15644972 Common - hypothetical protein HP0344 3 None None None 15644731 Pathogen - hypothetical protein HP0101 1 None None None 15645177 Common - hypothetical protein HP0552 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 15644759 Common - hypothetical protein HP0129 2 None None None 15645442 Common - hypothetical protein HP0823 49 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 15645629 Pathogen - hypothetical protein HP1015 1 None None None 15645303 Common - lipopolysaccharide biosynthesis protein (wbpB) HP0679 56 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 15646172 Common - penicillin-binding protein 2 (pbp2) HP1565 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 15645253 Common - hypothetical protein HP0629 64 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15644754 Common infC translation initiation factor IF-3 HP0124 208 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 15645956 Common - hypothetical protein HP1343 108 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 15646197 Pathogen omp1 outer membrane protein HP0009 1 None None None 15646005 Pathogen - outer membrane protein (omp30) HP1395 1 None None None 15645633 Common - serine protease (htrA) HP1019 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 15646145 Pathogen - hypothetical protein HP1537 2 None None None 15644977 Common - CTP synthetase HP0349 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 15645189 Pathogen - hypothetical protein HP0564 1 None None None 15645873 Common - hypothetical protein HP1259 147 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 15645140 Common - hypothetical protein HP0513 51 COG3586 COG3586, Uncharacterized conserved protein Function unknown 15644824 Common - enoyl-(acyl carrier protein) reductase HP0195 208 COG0623 FabI, Enoyl- acyl-carrier-protein 15644750 Pathogen - hypothetical protein HP0120 1 None None None 15644692 Pathogen - hypothetical protein HP0062 1 None None None 15645275 Common - fucosyltransferase HP0651 12 None None None 15646120 Pathogen - hypothetical protein HP1511 1 None None None 15646125 Pathogen - hypothetical protein HP1516 1 None None None 15645471 Common - hypothetical protein HP0852 15 COG2958 COG2958, Uncharacterized protein conserved in bacteria Function unknown 15645738 Common - hypothetical protein HP1124 11 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 15644817 Pathogen - hypothetical protein HP0188 1 None None None 15645925 Common rplP 50S ribosomal protein L16 HP1312 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 15644704 Common lspA lipoprotein signal peptidase HP0074 7 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 15645046 Common - hypothetical protein HP0418 7 None None None 15644768 Common - conserved hypothetical iron-sulfur protein HP0138 100 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 15645380 Common - hypothetical protein HP0761 7 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 15645601 Common - hypothetical protein HP0986 3 None None None 15645904 Common - hypothetical protein HP1291 24 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 15645862 Common - virulence associated protein homolog (vacB) HP1248 192 COG0557 VacB, Exoribonuclease R Transcription 15645829 Common - hypothetical protein HP1215 2 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 15645774 Common - hypothetical protein HP1160 207 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 15646020 Pathogen - hypothetical protein HP1410 1 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15645894 Common - anthranilate synthase component II (trpD) HP1281 235 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 15644907 Common - lipopolysaccharide heptosyltransferase-1 (rfaC) HP0279 80 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15645094 Common - hypothetical protein HP0466 4 None None None 15645741 Common - hypothetical protein HP1127 2 None None None 15644962 Common - Holliday junction resolvase-like protein HP0334 10 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 15645203 Common - hypothetical protein HP0578 38 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 15645322 Pathogen - hypothetical protein HP0699 1 None None None 15645918 Common rpsH 30S ribosomal protein S8 HP1305 234 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 15646012 Common - type I restriction enzyme R protein (hsdR) HP1402 137 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 15645237 Pathogen - hypothetical protein HP0612 1 None None None 15646101 Common - conserved hypothetical nifU-like protein HP1492 71 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 15645680 Pathogen - hypothetical protein HP1066 1 None None None 15645337 Common - ABC transporter, ATP-binding protein HP0715 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 15645347 Common - transcriptional regulator, putative HP0727 202 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 15645520 Common - hypothetical protein HP0902 10 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 15644712 Common - methyl-accepting chemotaxis transducer (tlpC) HP0082 109 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15646072 Pathogen - hypothetical protein HP1463 1 None None None 15644709 Pathogen - outer membrane protein (omp3) HP0079 3 COG1511 COG1511, Predicted membrane protein Function unknown 15645876 Common - NADH dehydrogenase subunit C HP1262 166 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 15646059 Common - putative inner membrane protein translocase component YidC HP1450 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 15645197 Common - adenine phosphoribosyltransferase HP0572 165 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 15645689 Common - conserved hypothetical secreted protein HP1075 8 COG3608 COG3608, Predicted deacylase General function prediction only 15645970 Common - hypothetical protein HP1358 4 None None None 15644742 Common - hypothetical protein HP0112 9 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 15645258 Common - quinone-reactive Ni/Fe hydrogenase (hydD) HP0634 43 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 15645803 Common - aspartate-semialdehyde dehydrogenase (asd) HP1189 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 15644678 Common - hydrogenase expression/formation protein (hypE) HP0047 117 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15645892 Common - tryptophan synthase subunit beta HP1278 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 15645185 Pathogen - hypothetical protein HP0560 1 None None None 15644795 Common - response regulator (ompR) HP0166 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15645763 Common - hypothetical protein HP1149 17 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 15645907 Common rpsD 30S ribosomal protein S4 HP1294 248 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 15645353 Common - hypothetical protein HP0733 3 None None None 15645363 Common - rod shape-determining protein (mreB) HP0743 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15645967 Common - nicotinate-nucleotide pyrophosphorylase HP1355 206 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 15646167 Common - cell division protein (ftsW) HP1560 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 15646183 Common - ABC transporter, ATP-binding protein (abc) HP1576 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 15645635 Common - response regulator HP1021 14 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 15645554 Common - hypothetical protein HP0938 17 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15645869 Common secG preprotein translocase subunit SecG HP1255 8 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 15646081 Common - type IIS restriction enzyme M protein (mod) HP1472 26 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15644893 Common - cytochrome c biogenesis protein (ccdA) HP0265 89 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 15645425 Common - hypothetical protein HP0806 117 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 15645503 Common - virulence factor mviN protein (mviN) HP0885 157 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 15644699 Common - urease accessory protein (ureF) HP0069 76 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 15646111 Common - hypothetical protein HP1502 3 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 15645315 Common - 3-oxoadipate coA-transferase subunit B (yxjE) HP0692 105 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 15646036 Pathogen - histidine-rich, metal binding polypeptide (hpn) HP1427 1 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 15644956 Common lpxK tetraacyldisaccharide 4'-kinase HP0328 108 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 15646033 Pathogen - hypothetical protein HP1424 1 None None None 15645818 Common rpmG 50S ribosomal protein L33 HP1204 85 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 15645752 Common - plasmid replication-partition related protein HP1138 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 15645959 Common - glyceraldehyde-3-phosphate dehydrogenase HP1346 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 15645739 Common - peptidoglycan associated lipoprotein precursor (omp18) HP1125 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 15645563 Pathogen - hypothetical protein HP0947 1 None None None 15644764 Common - 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (dhs1) HP0134 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 15644918 Common - diaminopimelate decarboxylase (dap decarboxylase) (lysA) HP0290 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 15645480 Common - hypothetical protein HP0861 53 COG2836 COG2836, Uncharacterized conserved protein Function unknown 15646041 Pathogen - histidine and glutamine-rich protein HP1432 1 None None None 15645190 Common - hypothetical protein HP0565 11 COG3059 COG3059, Predicted membrane protein Function unknown 15644687 Common - delta-1-pyrroline-5-carboxylate dehydrogenase HP0056 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 15645645 Common fliM flagellar motor switch protein FliM HP1031 105 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 15646054 Common - biopolymer transport protein (exbB) HP1445 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15645290 Common - anaerobic glycerol-3-phosphate dehydrogenase, subunit C (glpC) HP0666 170 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 15644875 Common - ATP-dependent RNA helicase, DEAD-box family (deaD) HP0247 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 15644932 Pathogen - hypothetical protein HP0304 1 None None None 15646113 Common - hypothetical protein HP1504 24 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 15644981 Common fliH flagellar assembly protein H HP0353 17 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 15645776 Common - hypothetical protein HP1162 39 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 15644878 Common - oligopeptide ABC transporter, ATP-binding protein (oppD) HP0250 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 15644736 Common - cystathionine gamma-synthase/cystathionine beta-lyase HP0106 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 15645104 Common gltX glutamyl-tRNA synthetase HP0476 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 15646169 Common - iron(III) ABC transporter, periplasmic iron-binding protein (ceuE) HP1562 39 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 15645711 Pathogen - hypothetical protein HP1097 1 None None None 15645996 Common - ribulose-phosphate 3-epimerase HP1386 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 15645157 Pathogen - cag pathogenicity island protein (cag11) HP0531 1 None None None 15644747 Common - hypothetical protein HP0117 49 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 15644664 Common - hypothetical protein HP0031 2 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 15645459 Common - flaA1 protein HP0840 195 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 15645165 Pathogen - cag pathogenicity island protein (cag18) HP0539 1 None None None 15645172 Pathogen - cag pathogenicity island protein (cag25) HP0546 1 None None None 15644938 Common - hypothetical protein HP0310 99 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 15645076 Pathogen - hypothetical protein HP0448 1 None None None 15645838 Common hemD uroporphyrinogen-III synthase HP1224 8 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 15646191 Common - O-sialoglycoprotein endopeptidase HP1584 247 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 15644852 Common - bifunctional methionine sulfoxide reductase A/B protein HP0224 206 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 15645589 Common - phosphoglyceromutase HP0974 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 15645580 Pathogen - hypothetical protein HP0964 2 None None None 15646199 Common - hypothetical protein HP0713 20 COG3177 COG3177, Uncharacterized conserved protein Function unknown 15645129 Pathogen - hypothetical protein HP0502 1 None None None 15645086 Pathogen - hypothetical protein HP0458 1 None None None 15645975 Common - hypothetical protein HP1363 201 COG0062 COG0062, Uncharacterized conserved protein Function unknown 15645403 Pathogen - hypothetical protein HP0784 1 None None None 15645412 Common def peptide deformylase HP0793 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 15645255 Common - quinone-reactive Ni/Fe hydrogenase, small subunit (hydA) HP0631 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 15646090 Common - hypothetical protein HP1481 10 COG0388 COG0388, Predicted amidohydrolase General function prediction only 15646179 Common - regulatory protein DniR HP1572 118 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15645035 Common - biotin sulfoxide reductase (bisC) HP0407 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 15645088 Pathogen - hypothetical protein HP0460 1 None None None 15645827 Common - polynucleotide phosphorylase/polyadenylase HP1213 230 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 15645408 Common - hypothetical protein HP0789 2 None None None 15645225 Common - multidrug resistance protein (spaB) HP0600 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15645969 Common - phosphatidylserine decarboxylase HP1357 89 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 15645539 Pathogen - outer membrane protein (omp22) HP0923 1 None None None 15644983 Common - GTP-binding protein LepA HP0355 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 15645235 Common - toxin-like outer membrane protein HP0610 9 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 15644733 Common - methyl-accepting chemotaxis protein (tlpB) HP0103 127 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 15644883 Common - adenylosuccinate synthetase HP0255 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 15644843 Common - CDP-diglyceride synthetase (cdsA) HP0215 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 15645831 Common - hypothetical protein HP1217 3 None None None 15645858 Common rpsR 30S ribosomal protein S18 HP1244 211 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 15645902 Pathogen - hypothetical protein HP1289 1 None None None 15645660 Common - hypothetical protein HP1046 138 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 15645053 Common - hypothetical protein HP0425 9 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 15644822 Common - fumarate reductase, cytochrome b subunit (frdC) HP0193 11 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 15645160 Pathogen - cag pathogenicity island protein (cag13) HP0534 1 None None None 15644967 Pathogen - hypothetical protein HP0339 3 None None None 15645065 Common - IS605 transposase (tnpA) HP0437 60 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15644894 Common - dihydroorotase (pyrC) HP0266 166 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 15645222 Common - penicillin-binding protein 1A (PBP-1A) HP0597 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 15644782 Common recA recombinase A HP0153 237 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 15645501 Common ruvA Holliday junction DNA helicase motor protein HP0883 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 15645519 Pathogen - hypothetical protein HP0901 1 None None None 15646130 Common - type III restriction enzyme R protein (res) HP1521 40 COG3587 COG3587, Restriction endonuclease Defense mechanisms 15644636 Common ribH riboflavin synthase subunit beta HP0002 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 15645576 Common glyQ glycyl-tRNA synthetase subunit alpha HP0960 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 15645816 Common rplK 50S ribosomal protein L11 HP1202 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 15645793 Common - phosphopentomutase HP1179 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 15644710 Pathogen - hypothetical protein HP0080 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 15645522 Common - hypothetical protein HP0906 20 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 15645217 Common - type III restriction enzyme R protein (res) HP0592 43 COG3587 COG3587, Restriction endonuclease Defense mechanisms 15645841 Common - cytochrome c553 HP1227 32 COG2863 COG2863, Cytochrome c553 Energy production and conversion 15644706 Common rpsT 30S ribosomal protein S20 HP0076 191 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 15645013 Pathogen - hypothetical protein HP0385 1 None None None 15646170 Common - alkyl hydroperoxide reductase (tsaA) HP1563 219 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15644805 Common - fructose-bisphosphate aldolase HP0176 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 15645560 Common - hypothetical protein HP0944 184 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 15645027 Common rpsA 30S ribosomal protein S1 HP0399 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 15645650 Common - 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (folK) HP1036 186 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 15645269 Common - soluble lytic murein transglycosylase (slt) HP0645 137 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 15645849 Common - hypothetical protein HP1235 7 None None None 15645009 Common - protoporphyrinogen oxidase (hemK) HP0381 218 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 15645885 Common - NADH dehydrogenase subunit L HP1271 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 15645120 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase HP0493 217 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15645762 Common trmD tRNA (guanine-N(1)-)-methyltransferase HP1148 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 15645552 Common - proline/betaine transporter (proP) HP0936 122 None None None 15645871 Common pyrE orotate phosphoribosyltransferase HP1257 61 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 15644815 Common - hypothetical protein HP0186 3 COG1479 COG1479, Uncharacterized conserved protein Function unknown 15645044 Common - cyclopropane fatty acid synthase (cfa) HP0416 142 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 15645117 Common - putative potassium channel protein, putative HP0490 57 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 15646124 Pathogen - hypothetical protein HP1515 1 None None None 15645375 Pathogen - hypothetical protein HP0756 1 None None None 15644863 Common - conserved hypothetical secreted protein HP0235 88 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15645657 Common - response regulator HP1043 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15644970 Pathogen - hypothetical protein HP0342 3 COG3326 COG3326, Predicted membrane protein Function unknown 15644690 Common - hypothetical protein HP0060 5 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 15646095 Common - hypothetical protein HP1486 79 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 15646129 Common - hypothetical protein HP1520 4 None None None 15644934 Common - glutamate-1-semialdehyde aminotransferase HP0306 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 15645789 Common - hypothetical protein HP1175 134 COG2252 COG2252, Permeases General function prediction only 15645392 Common - hypothetical protein HP0773 125 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 15645389 Common flhB flagellar biosynthesis protein FlhB HP0770 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 15644905 Common - ferredoxin HP0277 128 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15645727 Pathogen - outer membrane protein (omp24) HP1113 1 None None None 15644651 Common - hypothetical protein HP0018 22 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 15645860 Common rpsF 30S ribosomal protein S6 HP1246 208 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 15645986 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase HP1376 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 15645603 Common - IS605 transposase (tnpA) HP0988 60 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 15645620 Pathogen - hypothetical protein HP1005 1 None None None 15645796 Common - hypothetical protein HP1182 151 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15645697 Pathogen - hypothetical protein HP1083 1 None None None 15644641 Pathogen - hypothetical protein HP0007 1 None None None 15644648 Pathogen - hypothetical protein HP0015 1 None None None 15645820 Common - multidrug resistance protein (hetA) HP1206 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 15645308 Common fliP flagellar biosynthesis protein FliP HP0685 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 15644658 Pathogen - outer membrane protein (omp2) HP0025 1 None None None 15646153 Common - hypothetical protein HP1546 7 None None None 15645964 Pathogen - hypothetical protein HP1351 2 None None None 15645508 Common - hypothetical protein HP0890 217 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 15645301 Common - hypothetical protein HP0677 71 COG0730 COG0730, Predicted permeases General function prediction only 15645147 Pathogen - cag pathogenicity island protein (cag1) HP0520 1 None None None 15644752 Pathogen - hypothetical protein HP0122 1 None None None 15645485 Common greA transcription elongation factor GreA HP0866 204 COG0782 GreA, Transcription elongation factor Transcription 15645941 Common - cation efflux system protein (czcA) HP1328 95 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15644975 Common - hypothetical protein HP0347 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 15645627 Common dapA dihydrodipicolinate synthase HP1013 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 15645670 Pathogen - hypothetical protein HP1056 1 None None None 15644728 Common - threonine synthase HP0098 130 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 15645700 Common - hemolysin (tly) HP1086 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 15645954 Common - siderophore-mediated iron transport protein (tonB) HP1341 30 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 15645499 Pathogen - hypothetical protein HP0880 1 None None None 15646147 Common - ubiquinol cytochrome c oxidoreductase, Rieske 2Fe-2S subunit (fbcF) HP1540 101 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 15645278 Common - hypothetical protein HP0654 85 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 15645026 Pathogen - hypothetical protein HP0398 1 None None None 15644757 Pathogen - outer membrane protein (omp4) HP0127 1 None None None 15645679 Common - hypothetical protein HP1065 5 None None None 15645493 Pathogen - hypothetical protein HP0874 1 None None None 15645837 Common - hypothetical protein HP1223 39 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 15645458 Common - outer membrane protein P1 (ompP1) HP0839 9 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 15644949 Common gmk guanylate kinase HP0321 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 15644760 Pathogen - hypothetical protein HP0130 1 None None None 15645699 Common - hypothetical protein HP1085 2 None None None 15644969 Pathogen - hypothetical protein HP0341 1 None None None 15646160 Common - helicase HP1553 212 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 15646140 Common - D-fructose-6-phosphate amidotransferase HP1532 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 15646136 Pathogen - hypothetical protein HP1528 1 None None None 15644872 Common - signal-transducing protein, histidine kinase (atoS) HP0244 191 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 15645285 Common rnhA ribonuclease H HP0661 177 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 15645377 Common - hypothetical protein HP0758 29 COG2056 COG2056, Predicted permease General function prediction only 15645139 Common - glutamine synthetase (glnA) HP0512 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 15645591 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase HP0976 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 15644945 Pathogen - outer membrane protein (omp9) HP0317 1 None None None 15644926 Common - dipeptide ABC transporter, periplasmic dipeptide-binding protein (dppA) HP0298 212 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 15645740 Common tolB translocation protein TolB HP1126 117 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 15646040 Common ksgA dimethyladenosine transferase HP1431 242 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 15646165 Common flgC flagellar basal body rod protein FlgC HP1558 122 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 15645990 Common - prephenate dehydrogenase HP1380 156 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 15645487 Pathogen - hypothetical protein HP0868 1 None None None 15645339 Common - DNA polymerase III subunits gamma and tau HP0717 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 15646068 Common - hypothetical protein HP1459 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 15645019 Common - purine-binding chemotaxis protein (cheW) HP0391 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15646039 Common - conserved hypothetical ATP-binding protein HP1430 161 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 15645690 Common - hypothetical protein HP1076 3 None None None 15645545 Common - geranyltranstransferase (ispA) HP0929 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15645263 Common - hypothetical protein HP0639 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 15644964 Common - hypothetical protein HP0336 40 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15644688 Pathogen - hypothetical protein HP0057 1 None None None 15645684 Pathogen - hypothetical protein HP1070 1 None None None 15645107 Common - hypothetical protein HP0479 2 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15644912 Common - hypothetical protein HP0284 38 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 15645703 Common - hypothetical protein HP1089 15 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 15646055 Common - biopolymer transport protein (exbD) HP1446 20 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 15645647 Pathogen - hypothetical protein HP1033 1 None None None 15645469 Common - type I restriction enzyme M protein (hsdM) HP0850 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15645549 Common - hypothetical protein HP0933 18 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 15644940 Common - conserved hypothetical ATP-binding protein HP0312 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 15645998 Pathogen - hypothetical protein HP1388 1 None None None 15646034 Pathogen - hypothetical protein HP1425 1 None None None 15644774 Common - cytochrome c oxidase, monoheme subunit, membrane-bound (fixO) HP0145 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 15644994 Common - spore coat polysaccharide biosynthesis protein C HP0366 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 161353436 Common secD preprotein translocase subunit SecD HP1550 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 15645556 Common - amino acid ABC transporter, periplasmic binding protein (yckK) HP0940 167 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 15644987 Pathogen - hypothetical protein HP0359 1 None None None 15645565 Common - hypothetical protein HP0949 76 COG1576 COG1576, Uncharacterized conserved protein Function unknown 15645056 Common - phage/colicin/tellurite resistance cluster terY protein HP0428 7 COG4245 TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain General function prediction only 15645259 Common - hypothetical protein HP0635 6 None None None 15645329 Pathogen - outer membrane protein (omp15) HP0706 1 None None None 15645252 Common - hypothetical protein HP0628 81 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15645732 Common - gamma-glutamyltranspeptidase (ggt) HP1118 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 15645787 Pathogen - hypothetical protein HP1173 1 None None None 15645517 Common - hydrogenase expression/formation protein (hypC) HP0899 96 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 15645942 Common - cation efflux system protein (czcA) HP1329 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 15644672 Pathogen - hypothetical protein HP0041 1 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 15645008 Common - glutamate dehydrogenase HP0380 164 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 15645462 Common - thiamin phosphate pyrophosphorylase/hyroxyethylthiazole kinase (thiB) HP0843 206 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 15646083 Common tdk thymidylate kinase HP1474 225 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 15645957 Common - magnesium and cobalt transport protein (corA) HP1344 166 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 15646029 Common fliI flagellum-specific ATP synthase HP1420 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 15646106 Common - peptidyl-tRNA hydrolase HP1497 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 15646181 Common - riboflavin synthase subunit alpha HP1574 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 15646104 Common - transaldolase HP1495 90 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 15645809 Common - elongation factor G HP1195 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 15645178 Common - hypothetical protein HP0553 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 15645782 Common - carbon starvation protein (cstA) HP1168 108 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 15646096 Common - hypothetical protein HP1487 31 COG1511 COG1511, Predicted membrane protein Function unknown 15644697 Common - urease accessory protein (ureH) HP0067 65 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 15645233 Pathogen - hypothetical protein HP0608 1 None None None 15645195 Common - leucyl aminopeptidase HP0570 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 15645336 Common - RNA polymerase factor sigma-54 HP0714 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 15645758 Pathogen - hypothetical protein HP1144 1 None None None 15645320 Common - hypothetical protein HP0697 17 COG4647 AcxC, Acetone carboxylase, gamma subunit Secondary metabolites biosynthesis, transport, and catabolism 15645705 Common - alpha-ketoglutarate permease (kgtP) HP1091 113 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 15645434 Common - flagellar motor protein MotA HP0815 111 COG1291 MotA, Flagellar motor component Cell motility and secretion 15645327 Pathogen - hypothetical protein HP0704 1 None None None 15644980 Common fliG flagellar motor switch protein G HP0352 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 15645201 Common - signal peptidase I (lepB) HP0576 153 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 15645270 Common - UDP-glucose pyrophosphorylase (galU) HP0646 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 15644793 Common - signal-transducing protein, histidine kinase HP0164 153 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 15645743 Common - biopolymer transport protein (exbD) HP1129 131 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 15645365 Common - hypothetical protein HP0746 15 COG3401 COG3401, Fibronectin type 3 domain-containing protein General function prediction only 15645761 Common rplS 50S ribosomal protein L19 HP1147 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 15645091 Common - type I restriction enzyme M protein (hsdM) HP0463 155 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 15645003 Common - hypothetical protein HP0375 2 None None None 15645553 Common - hypothetical protein HP0937 8 None None None 15645414 Common tig trigger factor HP0795 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 15645243 Common adk adenylate kinase HP0618 230 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 15645747 Common - F0F1 ATP synthase subunit gamma HP1133 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 15645509 Common - hypothetical protein HP0891 126 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 15645171 Pathogen - cag pathogenicity island protein (cag24) HP0545 1 None None None 15645342 Pathogen - hypothetical protein HP0720 1 None None None 15645963 Common - protease HP1350 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 15644740 Common - co-chaperone and heat shock protein (grpE) HP0110 228 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 15644885 Common - conserved hypothetical secreted protein HP0257 7 COG3334 COG3334, Uncharacterized conserved protein Function unknown 15646014 Common - type I restriction enzyme S protein (hsdS) HP1404 44 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 15645851 Common - carbamoyl phosphate synthase small subunit HP1237 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 15645770 Pathogen - outer membrane protein (omp25) HP1156 1 None None None 15644849 Common - nifU-like protein HP0221 114 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 15646024 Common - hypothetical protein HP1414 109 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 15645149 Pathogen - cag pathogenicity island protein (cag4) HP0523 1 None None None 15644859 Common - hypothetical protein HP0231 3 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 15645521 Pathogen - phosphotransacetylase (pta) HP0905 1 COG0857 Pta, BioD-like N-terminal domain of phosphotransacetylase General function prediction only 15645384 Pathogen - hypothetical protein HP0765 1 None None None 15645778 Common - thioredoxin reductase (trxB) HP1164 121 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 15645312 Common - hypothetical protein HP0689 9 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 15644758 Pathogen - hypothetical protein HP0128 1 None None None 15645498 Common - hypothetical protein HP0879 8 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15645898 Common - conserved hypothetical secreted protein HP1285 27 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 15644841 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA HP0213 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 15645257 Common - quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit (hydC) HP0633 55 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 15645156 Common - cag pathogenicity island protein (cag10) HP0530 7 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 15645024 Common - hypothetical protein HP0396 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 15644973 Pathogen - hypothetical protein HP0345 1 COG4499 COG4499, Predicted membrane protein Function unknown 15645181 Pathogen - hypothetical protein HP0556 1 None None None 15645666 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase HP1052 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 15645952 Common - biopolymer transport protein (exbB) HP1339 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 15646142 Common - IS605 transposase (tnpB) HP1534 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15645935 Pathogen - hypothetical protein HP1322 1 None None None 15644695 Pathogen - hypothetical protein HP0065 1 None None None 15646149 Common - hypothetical protein HP1542 63 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 15646001 Pathogen - hypothetical protein HP1391 1 None None None 15645452 Pathogen - hypothetical protein HP0833 1 None None None 15644796 Common - hypothetical protein HP0167 4 None None None 15645550 Common - hypothetical protein HP0934 66 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 15645677 Common gidB glucose-inhibited division protein B HP1063 192 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 15646176 Common - hypothetical protein HP1569 4 None None None 15644726 Common - 2-hydroxyacid dehydrogenase HP0096 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 15644921 Common - para-aminobenzoate synthetase (pabB) HP0293 220 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 15645475 Common - hypothetical protein HP0856 4 None None None 15644833 Pathogen - hypothetical protein HP0204 1 None None None 15646121 Common - iron-regulated outer membrane protein (frpB) HP1512 37 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 15644990 Common - hypothetical protein HP0362 30 COG0795 COG0795, Predicted permeases General function prediction only 15645250 Common - tetrahydrodipicolinate N-succinyltransferase (dapD) HP0626 35 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 15645144 Common era GTP-binding protein Era HP0517 212 COG1159 Era, GTPase General function prediction only 15645401 Pathogen - hypothetical protein HP0782 1 None None None 15645625 Common - dihydroorotate dehydrogenase 2 HP1011 183 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 15645131 Pathogen - hypothetical protein HP0504 1 None None None 15645279 Common - protective surface antigen D15 HP0655 150 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 15645248 Common - hypothetical protein HP0624 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15644813 Common - hypothetical protein HP0184 5 None None None 15645119 Pathogen - hypothetical protein HP0492 1 None None None 15645802 Pathogen - hypothetical protein HP1188 1 None None None 15644954 Common - CMP-N-acetylneuraminic acid synthetase (neuA) HP0326 63 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 15644669 Common - hypothetical protein HP0036 4 None None None 15645033 Common - nifS-like protein HP0405 196 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 15645866 Common - oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (oppA) HP1252 161 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 161353439 Common rplO 50S ribosomal protein L15 HP1301 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 15645825 Pathogen - hypothetical protein HP1211 1 None None None 15644903 Common - ATP-dependent nuclease (addB) HP0275 17 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 15645002 Common - hypothetical protein HP0374 50 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 15645399 Pathogen - hypothetical protein HP0780 1 None None None 15645528 Pathogen - outer membrane protein (omp20) HP0912 1 None None None 15645122 Common - hypothetical protein HP0495 7 None None None 15645351 Common - hypothetical protein HP0731 4 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 15645424 Common - lipooligosaccharide 5G8 epitope biosynthesis-associated protein (lex2B) HP0805 14 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 15645847 Common - hypothetical protein HP1233 2 None None None 15645075 Common - hypothetical protein HP0447 55 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 15644784 Pathogen - hypothetical protein HP0155 1 None None None 15645137 Common - dihydrodipicolinate reductase HP0510 210 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 15645191 Common dapF diaminopimelate epimerase HP0566 180 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 15645619 Common - hypothetical protein HP1004 4 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 15646155 Common - hypothetical protein HP1548 10 None None None 15646108 Common - hypothetical protein HP1499 19 COG3886 COG3886, Predicted HKD family nuclease DNA replication, recombination, and repair 15645578 Common - acyl carrier protein (acpP) HP0962 199 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15644809 Common - apolipoprotein N-acyltransferase HP0180 64 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 15646094 Common - hypothetical protein HP1485 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 15644799 Common - hypothetical protein HP0170 5 None None None 15644982 Common - 1-deoxy-D-xylulose-5-phosphate synthase HP0354 208 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 15644638 Common - carbonic anhydrase (icfA) HP0004 143 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 15644879 Common - oligopeptide ABC transporter, permease protein (oppC) HP0251 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 15645083 Pathogen - hypothetical protein HP0455 1 None None None 15644803 Common - hypothetical protein HP0174 8 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 15645900 Common - transcriptional regulator (tenA) HP1287 76 COG0819 TenA, Putative transcription activator Transcription 15644653 Common - carboxynorspermidine decarboxylase (nspC) HP0020 57 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 15645923 Common rpsQ 30S ribosomal protein S17 HP1310 190 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 15645612 Common - IS605 transposase (tnpB) HP0997 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15644870 Pathogen - hypothetical protein HP0242 1 None None None 15645655 Common flhA flagellar biosynthesis protein A HP1041 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 15645916 Common rplR 50S ribosomal protein L18 HP1303 210 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 15646006 Common - hypothetical protein HP1396 13 None None None 15645882 Common - NADH dehydrogenase subunit I HP1268 188 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 15646099 Common - hypothetical protein HP1490 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 15644866 Common - prolyl-tRNA synthetase HP0238 239 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15645011 Pathogen - hypothetical protein HP0383 1 None None None 15644865 Common hemC porphobilinogen deaminase HP0237 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 15645971 Pathogen - hypothetical protein HP1359 1 None None None 15646047 Pathogen - conserved hypothetical lipoprotein HP1438 3 None None None 15645638 Common - co-chaperone-curved DNA binding protein A (CbpA) HP1024 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15645110 Pathogen - hypothetical protein HP0482 1 None None None 15645431 Common - hypothetical protein HP0812 29 COG1565 COG1565, Uncharacterized conserved protein Function unknown 15645681 Common - chemotaxis protein (cheY) HP1067 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 15645798 Common - hypothetical protein HP1184 136 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 15645049 Common - type 1 capsular polysaccharide biosynthesis protein J (capJ) HP0421 106 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 15645988 Common - competence lipoprotein (comL) HP1378 10 COG4105 ComL, DNA uptake lipoprotein General function prediction only 15645587 Common glyS glycyl-tRNA synthetase subunit beta HP0972 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 15645228 Pathogen - hypothetical protein HP0603 1 None None None 15645358 Common ddl D-alanyl-alanine synthetase A HP0738 177 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 15645390 Pathogen - hypothetical protein HP0771 1 None None None 15645169 Pathogen - cag pathogenicity island protein (cag22) HP0543 1 None None None 15645600 Pathogen - hypothetical protein HP0985 1 None None None 15645446 Common - ss-DNA binding protein 12RNP2 precursor HP0827 64 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 15645100 Pathogen - outer membrane protein (omp11) HP0472 1 None None None 15645379 Common - hypothetical protein HP0760 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 15645428 Common fliL flagellar basal body-associated protein FliL HP0809 23 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 15644908 Common - lipid A biosynthesis lauroyl acyltransferase HP0280 53 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 15645649 Common flhF flagellar biosynthesis regulator FlhF HP1035 241 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 15645367 Common - cell division protein (ftsE) HP0748 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 15645072 Common - hypothetical protein HP0444 4 None None None 15645109 Common - adenine specific DNA methyltransferase (MFOKI) HP0481 3 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 15645382 Common - cell division protein (ftsY) HP0763 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 15645874 Common - NADH dehydrogenase subunit A HP1260 161 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 15645547 Pathogen - hypothetical protein HP0931 1 None None None 15645017 Common - superoxide dismutase (sodB) HP0389 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 15644910 Common - hypothetical protein HP0282 9 COG3400 COG3400, Uncharacterized protein conserved in bacteria Function unknown 15646032 Common - hypothetical protein HP1423 27 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 15645296 Common - aspartate aminotransferase HP0672 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 15646066 Common - hypothetical protein HP1457 15 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 15646057 Common - ribonuclease P, protein component (rnpA) HP1448 6 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 15645715 Common - glucose-6-phosphate 1-dehydrogenase HP1101 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 15644828 Common - hypothetical protein HP0199 6 None None None 15645153 Common - cag pathogenicity island protein (cag7) HP0527 51 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 15645283 Common - hypothetical protein HP0659 14 None None None 15645491 Common - alkylphosphonate uptake protein (phnA) HP0872 79 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 15645164 Pathogen - cag pathogenicity island protein (cag17) HP0538 1 None None None 15644985 Common - short chain alcohol dehydrogenase HP0357 232 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 15645186 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase HP0561 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 15644762 Common - L-serine deaminase (sdaA) HP0132 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 15645543 Common - heat shock protein HtpX HP0927 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 15644700 Common ureE urease accessory protein UreE HP0070 11 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 15645610 Common - integrase/recombinase (xerD) HP0995 181 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15645675 Common - hypothetical protein HP1061 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 15645835 Common - hypothetical protein HP1221 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 15644947 Common argS arginyl-tRNA synthetase HP0319 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 15644915 Common - hypothetical protein HP0287 6 None None None 15645992 Pathogen - hypothetical protein HP1382 1 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 15644928 Common - dipeptide ABC transporter, permease protein (dppC) HP0300 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 15646025 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase HP1415 209 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 15646080 Common - type IIS restriction enzyme R protein (BCGIB) HP1471 4 None None None 15644868 Common - octaprenyl-diphosphate synthase (ispB) HP0240 237 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 15644936 Pathogen - hypothetical protein HP0308 1 None None None 15645640 Common - recombination factor protein RarA HP1026 238 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 15645709 Common - IS605 transposase (tnpB) HP1095 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15644743 Pathogen - hypothetical protein HP0113 1 None None None 15646209 Common - hypothetical protein HP1417m 59 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 15644681 Common - adenine specific DNA methyltransferase (dpnA) HP0050 126 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15646200 Pathogen omp16 outer membrane protein HP0722 1 None None None 15645481 Common - pantothenate kinase HP0862 28 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 15644942 Pathogen - hypothetical protein HP0314 1 None None None 15644856 Common - hypothetical protein HP0228 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 15645745 Common atpC F0F1 ATP synthase subunit epsilon HP1131 170 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 15645950 Common - hypothetical protein HP1337 145 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 15645432 Common - hypothetical protein HP0813 170 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 15646076 Pathogen - hypothetical protein HP1467 1 None None None 15645456 Common - hypothetical protein HP0837 12 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 15645800 Common - carbonic anhydrase HP1186 49 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 15645319 Common - N-methylhydantoinase HP0696 81 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 15646178 Common - rare lipoprotein A (rlpA) HP1571 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 15644772 Common - A/G-specific adenine glycosylase (mutY) HP0142 233 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 15646188 Common - methicillin resistance protein (llm) HP1581 175 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 15645193 Common - hypothetical protein HP0568 14 None None None 15645325 Pathogen - hypothetical protein HP0702 1 None None None 15645340 Common - hypothetical protein HP0718 73 COG1279 COG1279, Lysine efflux permease General function prediction only 15645330 Common mraW S-adenosyl-methyltransferase MraW HP0707 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 15644716 Common - hypothetical protein HP0086 83 COG0579 COG0579, Predicted dehydrogenase General function prediction only 15645887 Common - NADH dehydrogenase subunit N HP1273 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 15645734 Common - hypothetical protein HP1120 4 None None None 15645245 Common - recombination and DNA strand exchange inhibitor protein HP0621 103 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 15645947 Common - hypothetical protein HP1334 14 COG1432 COG1432, Uncharacterized conserved protein Function unknown 15646016 Common - biotin synthase HP1406 174 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 15644660 Common - isocitrate dehydrogenase (icd) HP0027 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 15645749 Pathogen - ATP synthase F1, subunit delta (atpH) HP1135 1 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 15644850 Pathogen - hypothetical protein HP0222 1 None None None 15645417 Common moaC molybdenum cofactor biosynthesis protein C HP0798 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 15645348 Common - hypothetical protein HP0728 95 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 15645813 Common rplL 50S ribosomal protein L7/L12 HP1199 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 15644996 Pathogen - hypothetical protein HP0368 1 None None None 15645723 Common porD pyruvate flavodoxin oxidoreductase subunit delta HP1109 32 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 15646134 Common - exodeoxyribonuclease (lexA) HP1526 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 15645981 Common - type III restriction enzyme R protein HP1371 11 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 15645507 Common - iron(III) dicitrate ABC transporter, permease protein (fecD) HP0889 157 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 15645780 Common - glucose-6-phosphate isomerase (pgi) HP1166 194 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 15644674 Common - mannose-6-phosphate isomerase (pmi) or (algA) HP0043 166 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 15645768 Common - flagellar assembly protein FliW HP1154 8 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 15645807 Common - aldo-keto reductase, putative HP1193 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 15646085 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HP1476 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 15645306 Pathogen - hypothetical protein HP0682 1 None None None 15644897 Common - conserved hypothetical ATP-binding protein HP0269 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 15645937 Pathogen - hypothetical protein HP1324 1 None None None 15645617 Pathogen - hypothetical protein HP1002 1 None None None 15646078 Pathogen - outer membrane protein (omp31) HP1469 1 None None None 15644952 Pathogen - outer membrane protein (omp10) HP0324 1 None None None 15644831 Common - 3-oxoacyl-(acyl carrier protein) synthase III HP0202 230 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 15645927 Common rplV 50S ribosomal protein L22 HP1314 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 15644959 Common - cell division inhibitor (minD) HP0331 158 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 15645530 Pathogen - hypothetical protein HP0914 1 None None None 15646008 Common - alanine dehydrogenase (ald) HP1398 161 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 15645623 Common - site-specific recombinase HP1009 5 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 15646064 Pathogen - hypothetical protein HP1455 1 None None None 15645047 Common - hypothetical protein HP0419 62 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 15645304 Common - ribonucleotide-diphosphate reductase subunit alpha HP0680 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 15644992 Common nrdF ribonucleotide-diphosphate reductase subunit beta HP0364 150 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 15645272 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase HP0648 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 15645477 Common - ADP-heptose synthase (rfaE) HP0858 155 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 15645440 Common uvrC excinuclease ABC subunit C HP0821 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 15644766 Common - bacterioferritin comigratory protein (bcp) HP0136 217 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 15645040 Pathogen - hypothetical protein HP0412 1 None None None 15644777 Pathogen - hypothetical protein HP0148 1 None None None 15645567 Common - hypothetical protein HP0951 7 None None None 15645468 Pathogen - hypothetical protein HP0849 1 None None None 15645079 Common - hypothetical protein HP0451 2 None None None 15645983 Common - rod shape-determining protein (mreB) HP1373 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 15646045 Pathogen - hypothetical protein HP1436 1 None None None 15645722 Common - pyruvate flavodoxin oxidoreductase subunit gamma HP1108 57 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 15645449 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A HP0830 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 15645692 Common - hypothetical protein HP1078 2 None None None 161353437 Common - flagellar assembly protein FliW HP1377 11 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 15644644 Common groES co-chaperonin GroES HP0011 179 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 15645060 Common - protein kinase C-like protein HP0432 6 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 15645912 Common - methionine aminopeptidase HP1299 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 15646002 Common - fibronectin/fibrinogen-binding protein HP1392 40 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 15644811 Common lysS lysyl-tRNA synthetase HP0182 245 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 15645496 Common ruvC Holliday junction resolvase HP0877 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 15644923 Common flgL flagellar hook-associated protein FlgL HP0295 48 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15645216 Common oorC 2-oxoglutarate-acceptor oxidoreductase subunit OorC HP0591 57 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 15645039 Pathogen - hypothetical protein HP0411 1 None None None 15646194 Common - hypothetical protein HP1587 8 COG4735 COG4735, Uncharacterized protein conserved in bacteria Function unknown 15645310 Common - iron(II) transport protein (feoB) HP0687 190 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 15645896 Common - hypothetical protein HP1283 2 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 15644901 Pathogen - hypothetical protein HP0273 1 None None None 15645000 Common dcd deoxycytidine triphosphate deaminase HP0372 145 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 15644724 Common - hypothetical protein HP0094 9 None None None 15644847 Pathogen - hypothetical protein HP0219 1 None None None 15646202 Common trpD anthranilate synthase component II HP1280 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 15645032 Common - protein kinase C inhibitor (SP:P16436) HP0404 226 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 15644756 Common rplT 50S ribosomal protein L20 HP0126 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 15645664 Common - homoserine kinase HP1050 123 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 15645735 Common - cytosine specific DNA methyltransferase (BSP6IM) HP1121 129 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 15645945 Common - co-chaperone and heat shock protein (dnaJ) HP1332 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 15646127 Pathogen - hypothetical protein HP1518 1 None None None 15644971 Common - hypothetical protein HP0343 2 None None None 15646144 Pathogen - hypothetical protein HP1536 1 None None None 15644839 Common - conserved hypothetical secreted protein HP0211 92 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 15645880 Common - NADH dehydrogenase subunit G HP1266 182 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 15645921 Common rplX 50S ribosomal protein L24 HP1308 197 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 15645265 Pathogen - hypothetical protein HP0641 1 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 15644745 Common - flagellin HP0115 112 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 15644826 Common - S-adenosylmethionine synthetase HP0197 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 15645113 Pathogen - hypothetical protein HP0486 1 None None None 15645407 Pathogen - hypothetical protein HP0788 1 None None None 15644836 Common - ATP-binding protein (mpr) HP0207 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 15644702 Common ureC urease subunit alpha HP0072 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 15644730 Common - hypothetical protein HP0100 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 15645438 Common - osmoprotection protein (proV) HP0819 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 15645273 Common aspA aspartate ammonia-lyase HP0649 238 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 15645911 Common infA translation initiation factor IF-1 HP1298 213 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 15645583 Common - virulence associated protein D (vapD) HP0967 6 COG3309 VapD, Uncharacterized virulence-associated protein D Function unknown 15644721 Common - type II restriction enzyme R protein (hsdR) HP0091 10 None None None 15645585 Common - nickel-cobalt-cadmium resistance protein (nccB) HP0970 38 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 15645515 Pathogen - hypothetical protein HP0897 1 None None None 15645210 Common - endonuclease III (nth) HP0585 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 15645717 Common glk glucokinase HP1103 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 15644898 Common - hypothetical protein HP0270 43 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 15645790 Pathogen - hypothetical protein HP1176 1 None None None 15645505 Pathogen - vacuolating cytotoxin HP0887 2 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 15644786 Common aroK shikimate kinase HP0157 198 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 15645526 Common - adenine specific DNA methyltransferase (HINDIIM) HP0910 47 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 15645792 Common - purine-nucleoside phosphorylase (deoD) HP1178 94 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 15645397 Common - hypothetical protein HP0778 10 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 15644719 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase HP0089 96 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 15645021 Common - chemotaxis protein (cheV) HP0393 162 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 15646187 Common - hypothetical protein HP1580 14 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15644818 Common - hypothetical protein HP0189 55 COG2862 COG2862, Predicted membrane protein Function unknown 15644714 Common rplM 50S ribosomal protein L13 HP0084 217 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 15645421 Common ribA GTP cyclohydrolase II HP0802 177 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 15645067 Common - hypothetical protein HP0439 4 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 15645070 Common - hypothetical protein HP0442 3 None None None 15645853 Pathogen - hypothetical protein HP1239 1 None None None 15645124 Common - sodium- and chloride-dependent transporter HP0497 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 15645630 Common - phosphatidylglycerophosphate synthase (pgsA) HP1016 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 15644891 Common - adenine specific DNA methyltransferase (hpaim) HP0263 74 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 15646092 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase HP1483 202 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 15645005 Common - thiol:disulfide interchange protein (dsbC), putative HP0377 7 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 15644807 Common - spore coat polysaccharide biosynthesis protein E HP0178 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 15645282 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B HP0658 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 15644800 Common prfB peptide chain release factor 2 HP0171 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 15645845 Common - DNA polymerase III subunit delta' HP1231 13 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 15645081 Common - hypothetical protein HP0453 4 None None None 15645470 Common - hypothetical protein HP0851 132 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 15645604 Common - IS605 transposase (tnpB) HP0989 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 15645889 Common algC phosphomannomutase HP1275 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 15645536 Common - hypothetical protein HP0920 139 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 15646069 Common dnaE DNA polymerase III subunit alpha HP1460 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 15645294 Pathogen - hypothetical protein HP0670 1 None None None 15645535 Common carB carbamoyl phosphate synthase large subunit HP0919 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 15644737 Common - cysteine synthetase (cysK) HP0107 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 15646163 Common - cell division protein (ftsI) HP1556 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane