Mycoplasma pneumoniae M129, complete genome NC_000912 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 13507763 Common rpoE DNA-directed RNA polymerase subunit delta MPN024 4 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 13507855 Common rpmI 50S ribosomal protein L35 MPN116 98 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 13507865 Common - hypothetical protein MPN126 39 COG0622 COG0622, Predicted phosphoesterase General function prediction only 13508092 Common dnaE DNA primase MPN353 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 13507997 Common yjcW sugar (ribose/galactose) ABC transporter ATP-binding subunit MPN258 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 13507829 Pathogen - adhesin P1 (group2) homolog MPN090 1 None None None 13508012 Common hit1 nucleotidyl hydrolase/transferase MPN273 215 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 13508016 Common lysS lysyl-tRNA synthetase MPN277 237 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 13507966 Common fus elongation factor G MPN227 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 13507744 Common serS seryl-tRNA synthetase MPN005 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 13507942 Pathogen - hypothetical protein MPN203 1 None None None 13507804 Common cdd cytidine deaminase MPN065 107 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 13508009 Pathogen - hypothetical protein MPN270 1 None None None 13508232 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase MPN493 47 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 13507949 Common secA preprotein translocase subunit SecA MPN210 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 13507897 Common yaaC riboflavin kinase (flavokinase)/FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase); bifunctional MPN158 209 COG0196 RibF, FAD synthase Coenzyme metabolism 13508024 Common prrB type I restriction enzyme ecokI specificity protein MPN285 30 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13508191 Pathogen hmw3 cytadherence accessory protein HMW3 MPN452 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 13507982 Common vacB 3'-5' exoribonuclease, RNase R MPN243 192 COG0557 VacB, Exoribonuclease R Transcription 13507810 Common yabC hypothetical protein (yabC) homolog; similar to Swiss-Prot Accession Number P37544, from B. subtilis MPN071 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 13507876 Common - hypothetical protein MPN137 29 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13508186 Common hmw1 cytadherence accessory protein HMW1 MPN447 8 COG5373 COG5373, Predicted membrane protein Function unknown 13507784 Common hisS histidyl-tRNA synthetase MPN045 244 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13507765 Common yyaF translation-associated GTPase MPN026 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 13508073 Common bcrA ABC transporter ATP-binding protein MPN334 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 13508096 Common lig DNA ligase MPN357 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 13508423 Pathogen - conserved hypothetical protein, suggestion: membrane transporter component MPN684 2 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 13508298 Pathogen - hypothetical protein MPN559 1 None None None 13508118 Common polA 5'-3' exonuclease (complete) MPN379 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 13507901 Pathogen - hypothetical protein MPN162 1 None None None 13508349 Common pstA Psta /Pstc-like ABC transporter; phosphate specific MPN610 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 13508156 Common P69 transport system permease protein P69 MPN417 2 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 13508131 Common pdhB pyruvate dehydrogenase E1-beta subunit MPN392 159 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 13508407 Common osmC hypothetical protein MPN668 84 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 13508288 Common - phosphodiesterase MPN549 78 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 161723289 Common thyA thymidylate synthase MPN320 144 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 13508263 Pathogen - hypothetical protein MPN524 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13508245 Pathogen - hypothetical protein MPN506 1 None None None 13507806 Common nusG transcription antitermination factor MPN067 31 COG0250 NusG, Transcription antiterminator Transcription 13508428 Common - Penicillin-binding protein-related factor A, putative recombinase MPN528a 16 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 13508188 Pathogen orf8 hypothetical protein MPN449 1 None None None 13508312 Common groEL chaperonin GroEL MPN573 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 13508393 Pathogen - hypothetical protein MPN654 1 None None None 13508173 Common dnaK molecular chaperone DnaK MPN434 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 13508082 Common - hypothetical protein MPN343 23 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13507890 Common - hypothetical protein MPN151 2 None None None 13508386 Pathogen - hypothetical protein MPN647 1 None None None 13507794 Common potA spermidine/putrescine transport ATP-binding prot MPN055 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 13508243 Pathogen - hypothetical protein MPN504 1 None None None 13508222 Common yibD bifunctional threonine dehydrogenase; galactosyltransferase MPN483 58 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 13508257 Pathogen - hypothetical protein MPN518 1 None None None 13508090 Common - methyltransferase MPN351 27 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 13508144 Pathogen - hypothetical protein MPN405 1 None None None 13507774 Pathogen - hypothetical protein MPN035 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 13508305 Common glpQ Glpq or Uplq glycerophosphoryl diester phosphodiesterase MPN566 23 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 13508221 Common - hypothetical protein MPN482 17 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 13508002 Common trx thioredoxin MPN263 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 13508089 Common ygiH hypothetical protein MPN350 170 COG0344 COG0344, Predicted membrane protein Function unknown 13508165 Common - SMC family, chromosome/DNA binding/protecting functions MPN426 196 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13508319 Pathogen - hypothetical protein MPN580 1 None None None 13507817 Common fruA fructose-permease IIBC component MPN078 82 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 13508121 Common - hypothetical protein MPN382 15 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 13507824 Pathogen - adhesin P1 (group2) homolog MPN085 1 None None None 13507971 Common dnaB replicative DNA helicase DnaB MPN232 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 13507846 Common - hypothetical protein MPN107 4 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 13507758 Common msbA transport ATP-binding protein MPN019 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 13507957 Common oppF but only N- and C-term; inbetween (500AA) seg and coil MPN218 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 13507924 Common adk adenylate kinase MPN185 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 13508296 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA MPN557 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 13508124 Pathogen - hypothetical protein MPN385 1 None None None 13508038 Common plsB 1-acyl-sn-glycerol-3-phosphate acyltransferase MPN299 135 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 13507843 Common - hypothetical protein MPN104 3 None None None 13508215 Common cmk cytidylate kinase MPN476 207 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 13507835 Pathogen - aa_permeases MPN096 1 None None None 13508053 Common yabB hypothetical protein MPN314 129 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 13508207 Pathogen - hypothetical protein MPN468 1 None None None 13508235 Common ulaA ascorbate-specific PTS system enzyme IIC MPN496 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 13507815 Pathogen uhpT hypothetical protein MPN076 2 None None None 13508411 Common hpt hypoxanthine-guanine phosphoribosyltransferase MPN672 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 13508346 Common pmsR methionine sulfoxide reductase A MPN607 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 13508321 Pathogen - hypothetical protein MPN582 1 None None None 13507915 Common rplX 50S ribosomal protein L24 MPN176 195 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 13507802 Common deoC deoxyribose-phosphate aldolase MPN063 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 13507968 Common ssb single-stranded DNA binding protein MPN229 7 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 13508377 Common - specificity determining subunit for restriction enzyme belonging to the K family of S proteins MPN638 19 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13508065 Common ysxB hypothetical protein MPN326 3 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 13508168 Common pgk phosphoglycerate kinase MPN429 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 13508209 Common pepX X-Pro dipeptidase MPN470 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 13507755 Common rimK similar to ribosomal S6 modification protein MPN016 52 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 13508193 Pathogen - hypothetical protein MPN454 1 None None None 13508334 Common lacA ribose-5-phosphate isomerase B MPN595 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 13508240 Common - hypothetical protein MPN501 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13507984 Common def peptide deformylase MPN245 199 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 13508020 Pathogen - hypothetical protein MPN281 1 None None None 13508087 Common - 5-formyl tetrahydrofolate cyclo-ligase MPN348 106 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 13507812 Common prs ribose-phosphate pyrophosphokinase MPN073 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 13508022 Pathogen - hypothetical protein MPN283 1 None None None 13508071 Common lon ATP-dependent protease Lon MPN332 209 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 13507857 Common - Similarity with Ribonuclease HII MPN118 20 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 13508151 Pathogen - hypothetical protein MPN412 1 None None None 13508102 Pathogen - hypothetical protein MPN363 1 None None None 13507882 Pathogen - hypothetical protein MPN143 1 None None None 13508230 Pathogen - membrane nuclease MPN491 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 13507863 Common hrcA heat-inducible transcription repressor MPN124 146 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 13508184 Common lip3 triacylglycerol lipase (lip) 3 MPN445 22 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 13508161 Common - TRNA (5-METHYLAMINOMETHYL-2-THIOURIDYLATE)-METHYLTRANSFERASE. MPN422 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 13507903 Common rpsJ 30S ribosomal protein S10 MPN164 241 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 13508080 Common mutB1 DNA helicase II (with Mycoplasma specific C-terminal domain) MPN341 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 13508371 Common pyrH uridylate kinase MPN632 234 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 13507889 Pathogen - hypothetical protein MPN150 1 None None None 13507950 Common uvrB excinuclease ABC subunit B MPN211 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 13508010 Pathogen - hypothetical protein MPN271 1 None None None 13507809 Pathogen - hypothetical protein MPN070 1 None None None 13507995 Pathogen - hypothetical protein MPN256 1 None None None 13508133 Common nox NADH oxidase MPN394 237 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 13508027 Pathogen - hypothetical protein MPN288 1 None None None 13508351 Pathogen - hypothetical protein MPN612 1 None None None 13507868 Pathogen - adhesin P1 (group 2) homolog MPN129 1 None None None 13508274 Common ruvA Holliday junction DNA helicase motor protein MPN535 24 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 13508261 Common - similar to methyltransferase MPN522 173 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 13508040 Common scpB segregation and condensation protein B MPN301 149 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 13508286 Common - dihydroacetone kinase MPN547 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 13508007 Pathogen - similar to PTS system: EIIB and N-term part of EIIC; bidomainal MPN268 2 COG1264 PtsG, Phosphotransferase system IIB components Carbohydrate transport and metabolism 13508198 Pathogen - hypothetical protein MPN459 1 None None None 13507848 Pathogen - C09_orf165 Protein MPN109 1 None None None 13507874 Common ugpA sn-glycerol-3-phosphate transport system permease protein MPN135 124 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 13507925 Common map methionine amino peptidase MPN186 241 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 13508202 Pathogen - hypothetical protein MPN463 1 None None None 13508271 Common licA similar to choline kinase MPN532 7 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 13508094 Common yacO tRNA/rRNA methyltransferase MPN355 212 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 13508357 Common dnaX gamma-like MPN618 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 13508119 Common fpg formamidopyrimidine-DNA glycosylase MPN380 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 13508400 Common K05_orf499 hypothetical protein MPN661 20 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 13508331 Pathogen - hypothetical protein MPN592 2 None None None 13508098 Pathogen - hypothetical protein MPN359 1 None None None 13508398 Common trmD tRNA (guanine-N1)-methyltransferase MPN659 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 13508014 Common yaaK hypothetical protein MPN275 19 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 13508171 Common artP abc transport ATP-binding protein MPN432 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 13508224 Pathogen - species specific lipoprotein MPN485 1 None None None 13508204 Pathogen - hypothetical protein MPN465 1 None None None 13508136 Common spoT p)ppGpp 3'-pyrophosphohydrolase MPN397 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 13507776 Pathogen - hypothetical protein MPN037 1 None None None 13508251 Pathogen - membrane export protein family MPN512 1 None None None 13508163 Common ylxM hypothetical protein MPN424 6 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 13508402 Common - hypothetical protein MPN663 186 COG0073 ARC1, EMAP domain General function prediction only 13508421 Common rpmH 50S ribosomal protein L34 MPN682 10 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 13507781 Pathogen - hypothetical protein MPN042 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 13508388 Pathogen - hypothetical protein MPN649 1 None None None 13507899 Common - hypothetical protein MPN160 2 None None None 13508310 Common lcnDR3 similar to hemolysin ABC-type exporter MPN571 103 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 13508391 Common mtlD mannitol-1-phosphate 5-dehydrogenase MPN652 33 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 13507879 Common orf4 DHH family phosphoesterase MPN140 72 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 13507796 Common potI spermidine/putrescine transport system permease MPN057 161 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 13507892 Common - hypothetical protein MPN153 79 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 13507741 Common xdj1 similar to j-domain of DnaJ MPN002 209 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 13508212 Common lip2 triacylglycerol lipase (lip) 2 MPN473 64 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 13508381 Pathogen - hypothetical protein MPN642 1 None None None 13508323 Pathogen - hypothetical protein MPN584 1 None None None 13507917 Common rpsN 30S ribosomal protein S14 MPN178 114 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 13508317 Pathogen - hypothetical protein MPN578 1 None None None 13508353 Pathogen - hypothetical protein MPN614 1 None None None 13507819 Common - Probably ABC transporter membrane protein subunit MPN080 12 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 13507822 Pathogen - hypothetical protein MPN083 1 None None None 13508418 Common ksgA dimethyladenosine transferase MPN679 237 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 13508063 Common nrdE ribonucleotide-diphosphate reductase subunit alpha MPN324 219 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 13507973 Pathogen - membrane export protein family MPN234 1 None None None 13507748 Common yabD hydrolase MPN009 235 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 13507951 Pathogen - hypothetical protein MPN212 1 None None None 13508307 Common spg small GTPase ERA involved in regulating metabolism and cell division MPN568 198 COG1159 Era, GTPase General function prediction only 13508348 Common pstB phosphate specific MPN609 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 13508126 Common - hypothetical protein MPN387 47 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13507910 Common rpsC 30S ribosomal protein S3 MPN171 245 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 13508178 Pathogen - hypothetical protein MPN439 2 None None None 13508135 Pathogen F11_orf887 protein export, secD like MPN396 1 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 13507954 Common oppB oligopeptide transport system permease protein OppB MPN215 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 13508368 Common tim triosephosphate isomerase MPN629 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 13508034 Pathogen - hypothetical protein MPN295 1 None None None 13507929 Common rpsK 30S ribosomal protein S11 MPN190 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 13508249 Pathogen - membrane export protein family MPN510 1 None None None 13508176 Pathogen - hypothetical protein MPN437 1 None None None 13508314 Pathogen - hypothetical protein MPN575 1 None None None 13507779 Pathogen - hypothetical protein MPN040 1 None None None 13508424 Common cysA sulfate transport ATP-binding protein MPN685 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 13507751 Pathogen - hypothetical protein MPN012 1 None None None 13508336 Common atpC F0F1 ATP synthase subunit epsilon MPN597 3 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 13508069 Pathogen - hypothetical protein MPN330 1 None None None 13508062 Common nrdI ribonucleotide reductase stimulatory protein MPN323 38 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 13508196 Pathogen - hypothetical protein MPN457 1 None None None 13508106 Pathogen - involved in cytadherence MPN367 1 None None None 13508200 Common ktrA KtrA, K+ Na+ uptake MPN461 113 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 13508356 Common rplM 50S ribosomal protein L13 MPN617 215 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 13507859 Common grpE heat shock protein GrpE MPN120 139 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 13507831 Pathogen - involved in cytadherence MPN092 1 None None None 13508218 Common - ACYL CARRIER PROTEIN PHOSPHODIESTERASE MPN479 64 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 13507853 Common cpt2 Acyltransferase MPN114 8 None None None 13507993 Common - hypothetical protein MPN254 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 13508042 Common pyk pyruvate kinase MPN303 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 13508025 Pathogen - hypothetical protein MPN286 1 None None None 13507913 Common rpsQ 30S ribosomal protein S17 MPN174 221 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 13508005 Common ygl1 similar to (oxido/arsenate) reductase MPN266 16 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 13507986 Common ptc1 protein phoshatase 2C homolog; similar to Swiss-Prot Accession Number P35182, from S. cerevisiae MPN247 116 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 13508364 Pathogen - osmotical inducible protein C like family; inducable by osmotic stress and by organic hydroperoxides MPN625 1 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 13507962 Common - HPr kinase/phosphorylase MPN223 58 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 13507769 Pathogen - hypothetical protein MPN030 1 COG0781 NusB, Transcription termination factor Transcription 13507906 Common rplW 50S ribosomal protein L23 MPN167 68 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 13508077 Pathogen - hypothetical protein MPN338 1 None None None 13508052 Pathogen - hypothetical protein MPN313 1 None None None 13508373 Pathogen - hypothetical protein MPN634 1 None None None 13508159 Common glpQ glycerophosphoryl diester phosphodiesterase MPN420 133 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 13507998 Common - sugar (ribose/galactose) ABC transporter permease subunit, but probably C-terminal MPN259 97 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 13508070 Common tig trigger factor MPN331 205 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 13508104 Common - hypothetical protein MPN365 23 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13507888 Pathogen - hypothetical protein MPN149 1 None None None 13507836 Pathogen - hypothetical protein MPN097 1 None None None 13507762 Common metS methionyl-tRNA synthetase MPN023 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13507820 Common glnQ glutamine transport ATP-binding protein MPN081 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 13508415 Pathogen K05_orf106 hypothetical protein MPN676 1 None None None 13507881 Pathogen orf6 involved in cytadherence MPN142 1 None None None 13508417 Common gltX glutamyl-tRNA synthetase MPN678 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 13507928 Common rpsM 30S ribosomal protein S13 MPN189 243 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 13508120 Common yidA HAD superfamily hydrolase/phosphatase MPN381 75 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 13507934 Common - similar to cobalt transport membrane protein MPN195 58 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 13508162 Pathogen - hypothetical protein MPN423 1 None None None 13507936 Common pepF oligoendopeptidase F MPN197 85 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 13508302 Common obgE GTPase ObgE MPN563 249 COG0536 Obg, Predicted GTPase General function prediction only 13508375 Common frr ribosome releasing factor MPN636 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 13507976 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A MPN237 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 13507872 Pathogen - putative lipoprotein MPN133 1 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 13508148 Pathogen - hypothetical protein MPN409 1 None None None 13508404 Common tuf elongation factor Tu MPN665 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 13508127 Pathogen - hypothetical protein MPN388 1 None None None 13508266 Pathogen - putative membrane integrated oxidoreductase MPN527 2 None None None 13508045 Common argI less (fragment) MPN306 231 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 13508276 Common mucB UV protection protein MucB MPN537 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 13507911 Common rplP 50S ribosomal protein L16 MPN172 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 13508325 Pathogen - hypothetical protein MPN586 1 None None None 13508055 Pathogen - hypothetical protein MPN316 1 None None None 13508342 Pathogen atpE F0F1 ATP synthase subunit C MPN603 2 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 13507798 Common gcp O-sialoglycoprotein endopeptidase MPN059 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 13507825 Pathogen - adhesin P1 (group2) homolog MPN086 1 None None None 13507945 Pathogen - hypothetical protein MPN206 1 None None None 13508227 Common - NifU-like protein MPN488 4 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 13508250 Pathogen - membrane export protein family MPN511 1 None None None 13508000 Common topA DNA topoisomerase I MPN261 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 13508379 Pathogen - hypothetical protein MPN640 1 None None None 13507777 Pathogen - hypothetical protein MPN038 1 None None None 13508284 Common rnc ribonuclease III MPN545 211 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 13508239 Pathogen - hypothetical protein MPN500 1 None None None 13508085 Common - Type I Restriction Enzyme hsdR (fragment) MPN346 7 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 13507754 Common - hypothetical protein MPN015 6 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 13507770 Pathogen - hypothetical protein MPN031 1 None None None 13508111 Pathogen - similarity to pertussis toxin subunit s1 MPN372 2 None None None 13508316 Pathogen - hypothetical protein MPN577 1 None None None 13507790 Common glpD glycerol-3-phospate dehydrogenase MPN051 131 COG0579 COG0579, Predicted dehydrogenase General function prediction only 13508383 Pathogen - hypothetical protein MPN644 1 None None None 13508236 Common - similar to PHOSPHOTRIESTERASE HOMOLOGY PROTEIN MPN497 9 COG1735 Php, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 13508108 Pathogen - hypothetical protein MPN369 1 None None None 13507955 Common amiD oligopeptide transport system permease protein AmiD MPN216 215 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 13508130 Common pdhC branched-chain alpha-keto acid dehydrogenase subunit E2 MPN391 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 13508311 Common - leucyl aminopeptidase MPN572 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 13507922 Common rplO 50S ribosomal protein L15 MPN183 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 13508282 Common fmt methionyl-tRNA formyltransferase MPN543 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 13508217 Common - hypothetical protein MPN478 209 COG0217 COG0217, Uncharacterized conserved protein Function unknown 13507808 Common rpmG 50S ribosomal protein L33 MPN069 6 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 13508137 Pathogen - hypothetical protein MPN398 1 None None None 13508113 Pathogen - hypothetical protein MPN374 1 None None None 13508044 Common arcA (C-terminal, fragment) MPN305 51 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 13508293 Pathogen - hypothetical protein MPN554 1 None None None 13507969 Common rpsR 30S ribosomal protein S18 MPN230 27 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 13508337 Common atpD F0F1 ATP synthase subunit beta MPN598 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 13508247 Pathogen - membrane export protein family MPN508 1 None None None 13508116 Pathogen - hypothetical protein MPN377 1 None None None 13508190 Common come3 competence locus operon protein 3 homolog; similar to Swiss-Prot Accession Number P39695, from B. subtilis MPN451 35 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 13508366 Common ptsI PEP-dependent HPr protein kinase phosphoryltransferase (Enzyme I) MPN627 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 13508154 Pathogen P37 high affinity transport system protein P37 MPN415 1 None None None 13508362 Common deaD similar to ATP-dependent RNA helicase deaD MPN623 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 13508396 Common - hypothetical protein MPN657 16 COG1284 COG1284, Uncharacterized conserved protein Function unknown 13508023 Pathogen - hypothetical protein MPN284 1 None None None 13507988 Common yjeQ conserved hypothetical protein, 154-190 similar to GTP/ATP binding proteins MPN249 157 COG1162 COG1162, Predicted GTPases General function prediction only 13507989 Common pgi glucose-6-phosphate isomerase MPN250 174 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 13508003 Common - 150-end, similar to phosphate hydrolising MPN264 31 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 13508018 Common lepA GTP-binding protein LepA MPN279 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 13507867 Pathogen - hypothetical protein MPN128 1 None None None 13508145 Common - acyl carrier protein MPN406 2 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 13507908 Common rpsS 30S ribosomal protein S19 MPN169 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 13507838 Pathogen - hypothetical protein MPN099 1 None None None 13507816 Common - hypothetical protein MPN077 3 None None None 13507767 Common trsB sugar transferase MPN028 136 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 13507996 Common galE UDP-glucose 4-epimerase MPN257 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 13507991 Common asnC asparaginyl-tRNA synthetase MPN252 247 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 13508289 Common - Thiamin biosynthesis protein MPN550 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 13507884 Common - hypothetical protein MPN145 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13508327 Pathogen - hypothetical protein MPN588 1 None None None 13507847 Common - hypothetical protein MPN108 14 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 13507964 Common rpsL 30S ribosomal protein S12 MPN225 222 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 13507932 Common CbiO cobalt transport ATP-binding protein MPN193 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 13508181 Pathogen - species specific lipoprotein MPN442 1 None None None 161723287 Common rpsP 30S ribosomal protein S16 MPN660 203 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 13507851 Pathogen - permease MPN112 4 None None None 13508129 Common pdhD dihydrolipoamide dehydrogenase MPN390 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 13507814 Common ywdF Glycosyl Transferase MPN075 107 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 13508268 Pathogen - bacterial histone like protein MPN529 4 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 13508255 Common rpoB DNA-directed RNA polymerase subunit beta MPN516 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 13507870 Pathogen - hypothetical protein MPN131 1 None None None 13507877 Common - hypothetical protein MPN138 3 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 13508050 Pathogen - hypothetical protein MPN311 1 None None None 13507845 Common pheT phenylalanyl-tRNA synthetase subunit beta MPN106 224 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 13508157 Common - hypothetical protein MPN419 46 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 13508300 Common udk uridine kinase MPN561 91 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 13507938 Pathogen - hypothetical protein MPN199 1 None None None 13508413 Common ldh L-lactate dehydrogenase MPN674 173 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 13507788 Pathogen - membrane export protein family MPN049 1 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 13507792 Common ptsH phosphocarrier protein HPr MPN053 95 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 13507886 Pathogen - hypothetical protein MPN147 1 None None None 13507760 Common dnaJ heat shock protein DnaJ MPN021 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 13507959 Common rplA 50S ribosomal protein L1 MPN220 223 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 13508304 Pathogen - hypothetical protein MPN565 1 None None None 13508122 Common yidA HAD superfamily hydrolase/phosphatase MPN383 102 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 13508370 Common tsf elongation factor Ts MPN631 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 13508036 Pathogen - hypothetical protein MPN297 1 None None None 13508369 Common yfiB hypothetical protein MPN630 13 COG1284 COG1284, Uncharacterized conserved protein Function unknown 13508291 Pathogen - hypothetical protein MPN552 1 None None None 13507894 Common infB translation initiation factor IF-2 MPN155 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 13508244 Pathogen - hypothetical protein MPN505 1 None None None 13508047 Common - aa_permeases MPN308 21 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 13507833 Pathogen - hypothetical protein MPN094 1 None None None 13508229 Common recA recombinase A MPN490 243 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 13507944 Pathogen - hypothetical protein MPN205 1 None None None 13508252 Common - hypothetical protein MPN513 2 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 13508406 Common gtaB UDP-glucose pyrophosphorylase MPN667 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 13508067 Common nfo endonuclease IV MPN328 111 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 13507902 Pathogen - hypothetical protein MPN163 1 None None None 13508344 Pathogen - hypothetical protein MPN605 1 None None None 13508141 Common proS prolyl-tRNA synthetase MPN402 85 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13507772 Common upp uracil phosphoribosyltransferase MPN033 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 13508380 Pathogen - hypothetical protein MPN641 1 None None None 13508160 Common - permease MPN421 16 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 13508060 Common dhfr dihydrofolate reductase MPN321 135 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 13507785 Common aspS aspartyl-tRNA synthetase MPN046 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13508039 Common scpA segregation and condensation protein A/unknown domain fusion protein MPN300 105 COG1354 COG1354, Uncharacterized conserved protein Function unknown 13507773 Common polC DNA polymerase III (dnaE) alpha chain MPN034 208 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 13507793 Pathogen - hypothetical protein MPN054 1 None None None 13507898 Common hlyC tlyC homolog, hemolysin activity doubtful MPN159 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 13508394 Pathogen - hypothetical protein MPN655 1 None None None 13508277 Common rplJ 50S ribosomal protein L10 MPN538 179 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 13508385 Pathogen - hypothetical protein MPN646 1 None None None 13508083 Pathogen - hypothetical protein MPN344 1 None None None 13508166 Common yidA hydrolase/phosphatase MPN427 76 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 13508101 Common - hemk family, similar to methyltransferase (S-adenosyl-methionine dependent) MPN362 154 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 13508035 Pathogen rpsU 30S ribosomal protein S21 MPN296 2 None None None 13508220 Common yihA GTPase EngB MPN481 199 COG0218 COG0218, Predicted GTPase General function prediction only 13507979 Common trxB thioredoxin reductase MPN240 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 13508409 Pathogen - hypothetical protein MPN670 1 None None None 13507939 Pathogen - hypothetical protein MPN200 1 None None None 13508143 Pathogen - hypothetical protein MPN404 1 None None None 13507923 Common secY preprotein translocase subunit SecY MPN184 235 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 13508412 Common - hypothetical protein MPN673 3 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 13507842 Pathogen - hypothetical protein MPN103 1 None None None 13508295 Common argS arginyl-tRNA synthetase MPN556 219 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13507818 Common fruK 1-phosphofructokinase MPN079 59 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 13507745 Common - thymidylate kinase MPN006 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 13507958 Common rplK 50S ribosomal protein L11 MPN219 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 13507803 Common deoA thymidine phosphorylase MPN064 122 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 13508233 Common yjfU similar to phosphotransferase protein II, component A, for pentitol, SGAT homolog MPN494 39 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 13508254 Common rpoC DNA-directed RNA polymerase subunit beta' MPN515 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 13508199 Common ktrB Trk-type K+ transport systems, membrane components MPN460 96 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 13508213 Common - coiled coil protein, putative structural protein involved in cytosceleton MPN474 53 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13507972 Pathogen - excreted conserved protein MPN233 1 None None None 13508308 Common - predicted metalloenzyme interacting with hemolysin MPN569 13 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 13508068 Pathogen - Ferric uptake regulator (Koonin for MG homologue) MPN329 1 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 13508234 Common - similar to PTS system: EIIB MPN495 27 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 13508345 Common eno phosphopyruvate hydratase MPN606 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 13508322 Pathogen - hypothetical protein MPN583 1 None None None 13507916 Common rplE 50S ribosomal protein L5 MPN177 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 13508329 Pathogen - hypothetical protein MPN590 1 None None None 13508269 Pathogen - hypothetical protein MPN530 1 None None None 13507823 Pathogen - hypothetical protein MPN084 1 None None None 13507832 Pathogen - involved in cytadherence MPN093 1 None None None 13507854 Common infC translation initiation factor IF-3 MPN115 211 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 13507904 Common rplC 50S ribosomal protein L3 MPN165 235 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 13508079 Common pcrA DNA helicase II MPN340 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 13508013 Pathogen A65_orf266 ABC transporter (sulfate/molybdenum) permease subunit MPN274 1 None None None 13508150 Pathogen - hypothetical protein MPN411 1 None None None 13507840 Pathogen - hypothetical protein MPN101 1 None None None 13507965 Common rpsG 30S ribosomal protein S7 MPN226 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 13507764 Common tsr fructose-bisphosphate aldolase MPN025 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 13507862 Common parC topoisomerase IV subunit A MPN123 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 13507821 Common tklB transketolase MPN082 220 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 13507783 Common tdk thymidine kinase MPN044 101 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 13508192 Pathogen - 30K adhesin-related protein MPN453 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 13507909 Common rplV 50S ribosomal protein L22 MPN170 215 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 13508206 Pathogen - hypothetical protein MPN467 1 None None None 13507875 Common ugpE sn-glycerol-3-phosphate transport system permease protein MPN136 128 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 13508017 Common yefE udp-galactopyranose mutase MPN278 55 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 13508185 Common rpsD 30S ribosomal protein S4 MPN446 233 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 13507956 Common oppD oligopeptide transport ATP-binding protein OppD MPN217 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 13508155 Common P29 ATP-binding protein P29 MPN416 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 13508088 Common - hypothetical protein MPN349 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 13507757 Common pmd1 transport ATP-binding protein MPN018 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 13507896 Pathogen - hypothetical protein MPN157 1 None None None 13508091 Common sigA RNA polymerase sigma factor RpoD MPN352 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 13508216 Pathogen - hypothetical protein MPN477 1 None None None 13508115 Pathogen - hypothetical protein MPN376 1 None None None 13508372 Common - hypothetical protein MPN633 2 None None None 13508280 Common rpsT 30S ribosomal protein S20 MPN541 40 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 13508330 Pathogen - hypothetical protein MPN591 1 None None None 13508134 Common apt adenine phosphoribosyltransferase MPN395 174 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 13508352 Pathogen - hypothetical protein MPN613 1 None None None 13508169 Common gap glyceraldehyde-3-phosphate dehydrogenase MPN430 220 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 13508074 Pathogen - hypothetical protein MPN335 1 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 13507766 Pathogen - hypothetical protein MPN027 1 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 13508422 Common devA ABC transporter subunit MPN683 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 13508095 Common cysS cysteinyl-tRNA synthetase MPN356 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13508264 Common - hypothetical protein MPN525 3 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 13508049 Common - Cytadherence High Molecular Weight Protein 2 (SwissProt HMW2_MYCPN) MPN310 192 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 13507805 Common cpsG two functions are possible, as both enzyme are homologous to each other: phosphomannomutase or phosphoglucomutase MPN066 234 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 13508242 Pathogen - protein family involved in cytadherence MPN503 1 None None None 161723288 Common nadD putative nicotinate-nucleotide adenylyltransferase MPN336 178 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 13508187 Common - hypothetical protein MPN448 5 None None None 13508205 Pathogen - hypothetical protein MPN466 1 None None None 13507869 Pathogen - hypothetical protein MPN130 1 None None None 13508287 Common - pseudouridine synthase MPN548 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 13508290 Pathogen - hypothetical protein MPN551 2 None None None 13508347 Common phoU phosphate transport system regulatory protein MPN608 31 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 13508211 Common degV hypothetical protein MPN472 48 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 13508401 Common pilB methionine sulfoxide reductase B MPN662 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 13507834 Common - aa_permeases MPN095 3 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 13508223 Pathogen - hypothetical protein MPN484 1 None None None 13507919 Common rplF 50S ribosomal protein L6 MPN180 235 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 13508340 Common atpH F0F1 ATP synthase subunit delta MPN601 49 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 13508174 Common - permease MPN435 6 COG0392 COG0392, Predicted integral membrane protein Function unknown 13507893 Common nusA transcription elongation factor NusA MPN154 216 COG0195 NusA, Transcription elongation factor Transcription 13508426 Pathogen - hypothetical protein MPN687 1 None None None 13507795 Common potB spermidine/putrescine transport system permease MPN056 112 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 13508030 Common - hypothetical protein MPN291 4 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 13508318 Pathogen - hypothetical protein MPN579 1 None None None 13508081 Common hsdM type I restriction enzyme HsdM MPN342 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 13508387 Pathogen - hypothetical protein MPN648 1 None None None 13508392 Common mtlF PTS system mannitol-specific component IIA (EIIA-MTL) MPN653 17 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 13507749 Pathogen - hypothetical protein MPN010 1 None None None 13508324 Pathogen - hypothetical protein MPN585 1 None None None 13507952 Pathogen - hypothetical protein MPN213 1 None None None 13507918 Common rpsH 30S ribosomal protein S8 MPN179 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 13508037 Common acpS 4'-phosphopantetheinyl transferase MPN298 13 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 13508320 Pathogen - hypothetical protein MPN581 2 None None None 13508389 Pathogen - hypothetical protein MPN650 1 None None None 13507742 Common gyrB DNA gyrase subunit B MPN003 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 13508064 Common rplU 50S ribosomal protein L21 MPN325 187 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 13508057 Common - amino acid permease MPN318 50 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 13508256 Common - suggest reductase homologue MPN517 47 COG0431 COG0431, Predicted flavoprotein General function prediction only 13507940 Common - hypothetical protein MPN201 24 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13508046 Common arcC carbamate kinase MPN307 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 13507775 Pathogen - hypothetical protein MPN036 1 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 13508123 Common leuS leucyl-tRNA synthetase MPN384 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13508177 Pathogen - hypothetical protein MPN438 1 None None None 13508309 Pathogen - hypothetical protein MPN570 1 None None None 13508410 Common ftsH cell division protein FtsH MPN671 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 13508279 Pathogen rpmF 50S ribosomal protein L32 MPN540 1 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 13508419 Common - putative inner membrane protein translocase component YidC MPN680 42 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 13508315 Common glyA serine hydroxymethyltransferase MPN576 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 13507778 Pathogen - hypothetical protein MPN039 1 None None None 13508140 Common greA transcription elongation factor GreA MPN401 204 COG0782 GreA, Transcription elongation factor Transcription 13507743 Common gyrA DNA gyrase subunit A MPN004 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 13508054 Common yabC SAM-Dependent Methytransferase (Koonin for MG ortholog) MPN315 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 13507978 Pathogen - hypothetical protein MPN239 1 COG2188 PhnF, Transcriptional regulators Transcription 13508194 Pathogen ctaD hypothetical protein MPN455 1 None None None 13508354 Common hsdS hypothetical protein MPN615 24 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13508164 Common ftsY cell division protein FtsY MPN425 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 13507974 Common ung uracil-DNA glycosylase MPN235 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 13508103 Pathogen - hypothetical protein MPN364 1 None None None 13507994 Pathogen - hypothetical protein MPN255 1 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 13508001 Pathogen A65_orf475 conserved hypothetical protein, similar to reticulocyte binding protein MPN262 1 None None None 13508015 Pathogen - hypothetical protein MPN276 2 None None None 13508231 Common yjfW L-xylulose 5-phosphate 3-epimerase MPN492 21 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 13507756 Common mtd1 5,10-methylene-tetrahydrofolate dehydrogenase MPN017 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 13508183 Pathogen - hypothetical protein MPN444 2 None None None 13508214 Common engA GTP-binding protein EngA MPN475 225 COG1160 COG1160, Predicted GTPases General function prediction only 13507947 Common rpsB 30S ribosomal protein S2 MPN208 238 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 13508378 Pathogen - hypothetical protein MPN639 1 None None None 13508086 Common hsdR Type I Restriction Enzyme (fragment) MPN347 109 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 13508093 Common grs1 glycyl-tRNA synthetase MPN354 90 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 13508021 Pathogen - hypothetical protein MPN282 1 None None None 13508011 Pathogen - hypothetical protein MPN272 1 None None None 13507983 Common - hypothetical protein MPN244 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 13508072 Pathogen F10_orf750 hypothetical protein MPN333 1 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 13507801 Common deoD purine nucleoside phosphorylase MPN062 97 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 13508152 Pathogen - hypothetical protein MPN413 1 None None None 13507967 Common rpsF 30S ribosomal protein S6 MPN228 5 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 13507856 Common rplT 50S ribosomal protein L20 MPN117 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 13508248 Pathogen - membrane export protein family MPN509 1 None None None 13507860 Pathogen - hypothetical protein MPN121 1 None None None 13507852 Pathogen - Similarity to G3P transporters MPN113 2 None None None 13507827 Pathogen - hypothetical protein MPN088 1 None None None 13508208 Pathogen - hypothetical protein MPN469 1 None None None 13508008 Common ysr1 hypothetical protein MPN269 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 13508241 Pathogen - hypothetical protein MPN502 1 None None None 13508117 Common dnaE DNA polymerase III alpha subunit MPN378 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 13508259 Common ileS isoleucyl-tRNA synthetase MPN520 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13508197 Pathogen - hypothetical protein MPN458 1 None None None 13507849 Common - hypothetical protein MPN110 15 COG4889 COG4889, Predicted helicase General function prediction only 13508203 Pathogen - involved in cytadherence MPN464 1 None None None 13508374 Common - hypothetical protein MPN635 2 None None None 13507873 Common ugpC sn-glycerol-3-phosphate transport system permease protein MPN134 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 13508397 Common rplS 50S ribosomal protein L19 MPN658 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 13508273 Pathogen - conserved hypothetical, RNA-expressed MPN534 1 None None None 13508032 Common lspA signal peptidase II MPN293 5 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 13508285 Common plsX fatty acid/phospholipid synthesis protein MPN546 176 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 13508262 Pathogen - probably membrane component, similar to STARP antigen MPN523 2 None None None 13508360 Common - similar to metallo hydrolase MPN621 133 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 13508420 Common rnpA RNaseP C5 chain MPN681 6 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 13508332 Pathogen - hypothetical protein MPN593 1 None None None 13508167 Common eutD phosphotransacetylase MPN428 157 COG0280 Pta, Phosphotransacetylase Energy production and conversion 13507883 Pathogen - hypothetical protein MPN144 1 None None None 13508097 Pathogen - hypothetical protein MPN358 1 None None None 13508270 Common clpB ATP-dependent protease binding subunit ClpB MPN531 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 13508390 Common mtlA similar to mannitol-specific PRS EIIBC MPN651 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 13507926 Common infA initiation factor 1 MPN187 211 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 13508339 Common atpA F0F1 ATP synthase subunit alpha MPN600 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 13507891 Pathogen - hypothetical protein MPN152 1 None None None 13508110 Pathogen - hypothetical protein MPN371 1 None None None 13508179 Pathogen - hypothetical protein MPN440 1 None None None 13508297 Common gidB methyltransferase GidB MPN558 154 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 13508358 Common uvrA excinuclease ABC subunit A MPN619 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 13507878 Common - hypothetical protein MPN139 2 None None None 13507927 Common rpmJ 50S ribosomal protein L36 MPN188 129 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 13508125 Common yaaF DEOXYGUANOSINE KINASE/ DEOXYADENOSINE KINASE MPN386 12 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 13508078 Pathogen - hypothetical protein MPN339 1 None None None 13508238 Pathogen - hypothetical protein MPN499 1 None None None 13508147 Common - hypothetical protein MPN408 3 None None None 13508172 Common cbiO abc transport ATP-binding protein MPN433 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 13508359 Pathogen - hypothetical protein MPN620 1 None None None 13507828 Common hsdS hypothetical protein MPN089 22 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13507935 Common truA tRNA pseudouridine synthase A MPN196 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 13508292 Common thrSv threonyl-tRNA synthetase MPN553 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13508051 Pathogen - hypothetical protein MPN312 1 None None None 13508376 Common cdsA CDP-diglyceride synthetase MPN637 73 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 13507740 Common dnaN DNA polymerase III beta subunit MPN001 86 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 13507753 Common dnaE hypothetical protein MPN014 10 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 13508299 Common arcA arginine deiminase MPN560 48 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 13507761 Common pip proline iminopeptidase MPN022 97 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 13508237 Common araD L-ribulose-5-phosphate 4-epimerase MPN498 71 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 13507905 Common rplD 50S ribosomal protein L4 MPN166 215 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 13507912 Pathogen rpmC 50S ribosomal protein L29 MPN173 2 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 13508403 Common degV hypothetical protein MPN664 13 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 13507933 Common hisP cobalt transport ATP-binding protein MPN194 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 13508326 Pathogen - hypothetical protein MPN587 1 None None None 13508058 Pathogen gap1 general amino acid permease GAP1 homolog; similar to Swiss-Prot Accession Number P19145, from S. cerevisiae MPN319 2 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 13507948 Common mgtA cation-transporting P-type ATPase MPN209 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 13507837 Pathogen - hypothetical protein MPN098 1 None None None 13508265 Pathogen - hypothetical protein MPN526 1 None None None 13507880 Pathogen P1 ADP1_MYCPN adhesin P1 MPN141 1 None None None 13508365 Pathogen - hypothetical protein MPN626 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 13508142 Pathogen - hypothetical protein MPN403 1 None None None 13508341 Common atpF F0F1 ATP synthase subunit B MPN602 18 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 13507747 Common trmE tRNA modification GTPase TrmE MPN008 220 COG0486 ThdF, Predicted GTPase General function prediction only 13508138 Pathogen - hypothetical protein MPN399 1 None None None 13507960 Common pth peptidyl-tRNA hydrolase MPN221 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 13508382 Pathogen - hypothetical protein MPN643 1 None None None 13508048 Common P65 hypothetical protein MPN309 3 None None None 13508226 Common nifS putative cysteine desulfurase MPN487 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 13508258 Common lip3 triacylglycerol lipase (lip) 3 MPN519 14 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 13508006 Common ppnK inorganic polyphosphate/ATP-NAD kinase MPN267 192 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 13508099 Common rpmE 50S ribosomal protein L31 MPN360 73 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 13508031 Common yceC similar to RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE D MPN292 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 13508225 Pathogen - hypothetical protein MPN486 1 None None None 13508272 Common ackA acetate kinase MPN533 162 COG0282 ackA, Acetate kinase Energy production and conversion 13508033 Common - similar to intracellular protease MPN294 4 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 13508355 Common rpsI 30S ribosomal protein S9 MPN616 241 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 13508313 Common groES co-chaperonin GroES MPN574 47 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 13508112 Pathogen - hypothetical protein MPN373 1 None None None 13507953 Pathogen - hypothetical protein MPN214 1 None None None 13508182 Common deaD RNA helicase, eIF4-A translation initiation factor MPN443 221 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 13507752 Common - hypothetical protein MPN013 4 None None None 13508367 Common pgm phosphoglyceromutase MPN628 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 13508283 Common - hypothetical protein MPN544 11 None None None 13508219 Common valS valyl-tRNA synthetase MPN480 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13508195 Pathogen - hypothetical protein MPN456 1 None None None 13507811 Common yabF similar to nucelotidyl transferase/polynicleotide cleavage MPN072 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 13507921 Common rpsE 30S ribosomal protein S5 MPN182 221 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 13508201 Pathogen - hypothetical protein MPN462 1 None None None 13507992 Common pgsA phosphatidylglycerophosphate synthase MPN253 172 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 13508427 Common soj ParA family of ATPase involved in chromosome partition MPN688 209 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 13507797 Common - hypothetical protein MPN058 7 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 13508210 Pathogen rpmG 50S ribosomal protein L33 MPN471 3 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 13507943 Pathogen - hypothetical protein MPN204 1 None None None 13508260 Common ygl3 putative rRNA methylase MPN521 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 13508061 Common nrdF ribonucleotide-diphosphate reductase subunit beta MPN322 56 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 13507861 Common parB topoisomerase IV subunit B MPN122 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 13507830 Pathogen - hypothetical protein MPN091 1 None None None 13507850 Common - hypothetical protein MPN111 16 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 13507858 Common - contains j-domain of DnaJ; and a domain common to cytadherence proteins MPN119 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 13507782 Common glpF glycerol uptake facilitator MPN043 78 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 13508028 Common hsdS1B this protein specifications means only that it is a type I restriction with enzyme ecokI specificity protein MPN289 11 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13507937 Common mte1 adenine-specific methyltransferase EcoRI MPN198 4 None None None 13508363 Common rpmB 50S ribosomal protein L28 MPN624 17 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 13508246 Common - type I restriction enzyme ecokI specificity protein (hsdS) homolog MPN507 27 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13508128 Common lplA lipoate protein ligase MPN389 81 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 13507887 Pathogen - hypothetical protein MPN148 1 None None None 13507789 Common glpK glycerol kinase MPN050 180 COG0554 GlpK, Glycerol kinase Energy production and conversion 13508333 Pathogen - hypothetical protein MPN594 1 None None None 13507977 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B MPN238 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 13508301 Common outB probable NH(3)-dependent NAD(+) synthetase MPN562 203 COG0171 NadE, NAD synthase Coenzyme metabolism 13508105 Pathogen - involved in cytadherence MPN366 1 None None None 13507866 Pathogen - hypothetical protein MPN127 1 None None None 13507900 Common - hypothetical protein MPN161 12 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 13507961 Common yacA similar to PP-loop superfamily ATPase/cell cycle protein MESJ homologues MPN222 117 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 13507985 Common gmk membrane-associated guanylate kinase homologue MPN246 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 13507931 Common rplQ 50S ribosomal protein L17 MPN192 215 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 13507930 Common rpoA DNA-directed RNA polymerase subunit alpha MPN191 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 13508056 Common ftsZ cell division protein FtsZ MPN317 231 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 13508343 Common atpB F0F1 ATP synthase subunit A MPN604 11 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 13507839 Pathogen - hypothetical protein MPN100 1 None None None 13507813 Common smpB SsrA-binding protein MPN074 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 13508267 Common ppa inorganic pyrophosphatase MPN528 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 13507914 Common rplN 50S ribosomal protein L14 MPN175 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 13508328 Pathogen - hypothetical protein MPN589 1 None None None 13508180 Pathogen - hypothetical protein MPN441 1 None None None 13507826 Pathogen - adhesin P1 (group2) homolog MPN087 1 None None None 13508149 Pathogen - hypothetical protein MPN410 1 None None None 13507970 Common rplI 50S ribosomal protein L9 MPN231 149 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 13508275 Common ruvB Holliday junction DNA helicase B MPN536 222 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 13508350 Common - similar to phosphate binding protein Psts MPN611 27 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 13507871 Pathogen - hypothetical protein MPN132 1 None None None 13508019 Common - similar to single stranded RNA(DNA) processing enzyme MPN280 150 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 13507841 Pathogen - involved in cytadherence MPN102 1 None None None 13508405 Pathogen - hypothetical protein MPN666 2 None None None 13508416 Common - similar to ATPase MPN677 88 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 13507920 Common rplR 50S ribosomal protein L18 MPN181 10 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 13508414 Pathogen - hypothetical protein MPN675 1 None None None 13508303 Common adh similar to NADP-dependent alcohol dehydrogenase MPN564 194 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 13508158 Common alaS alanyl-tRNA synthetase MPN418 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13507981 Pathogen secG preprotein translocase subunit SecG MPN242 2 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 13508043 Common arcA (N-terminal, fragment) MPN304 50 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 13508361 Common rpsO 30S ribosomal protein S15 MPN622 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 13507791 Pathogen - putative lipoprotein MPN052 5 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 13507799 Common metX S-adenosylmethionine synthetase MPN060 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 13508306 Pathogen P200 similar to cyto adherence proteins MPN567 1 None None None 13508107 Common - hypothetical protein MPN368 2 None None None 13507786 Common - hypothetical protein MPN047 23 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 13507895 Common rbfA ribosome binding factor A MPN156 12 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 13508384 Pathogen - hypothetical protein MPN645 1 None None None 13507946 Common ptsG PTS system, glucose-specific IIABC component MPN207 58 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 13508253 Pathogen - hypothetical protein MPN514 1 None None None 13508408 Common tyrS tyrosyl tRNA synthetase MPN669 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13508026 Pathogen - hypothetical protein MPN287 1 None None None 13507807 Pathogen secE preprotein translocase subunit SecE MPN068 1 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 13508100 Common prfA peptide chain release factor 1 MPN361 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 13508066 Common rpmA 50S ribosomal protein L27 MPN327 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 13508189 Pathogen orf7 hypothetical protein MPN450 2 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 13508278 Common rplL 50S ribosomal protein L7/L12 MPN539 209 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 13507941 Pathogen - hypothetical protein MPN202 1 None None None 13507771 Common - hydrolase MPN032 13 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 13507759 Common yb95 similar to helicases MPN020 135 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 13508109 Pathogen - hypothetical protein MPN370 1 None None None 13507864 Common uvrC excinuclease ABC subunit C MPN125 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 13508170 Common - permease MPN431 48 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 13508114 Pathogen - hypothetical protein MPN375 1 None None None 13508338 Common atpG F0F1 ATP synthase subunit gamma MPN599 206 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 13507750 Pathogen - hypothetical protein MPN011 1 None None None 13508228 Pathogen - species specific lipoprotein MPN489 2 None None None 13508294 Pathogen - hypothetical protein MPN555 2 None None None 13508281 Pathogen - hypothetical protein MPN542 2 None None None 13508335 Pathogen - hypothetical protein MPN596 1 None None None 13508175 Pathogen - hypothetical protein MPN436 2 None None None 13508153 Pathogen - hypothetical protein, involved in cytadherence MPN414 1 None None None 13507907 Common rplB 50S ribosomal protein L2 MPN168 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 13507999 Common rbsC sugar (ribose/galactose) ABC transporter permease subunit MPN260 95 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 13508146 Common - lipase MPN407 3 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 13507787 Pathogen - membrane export protein family MPN048 1 None None None 13508425 Common dnaA chromosomal replication initiation protein MPN686 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 13508139 Pathogen - hypothetical protein MPN400 1 None None None 13507980 Common - hypothetical protein MPN241 31 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 13508395 Common rbgA ribosomal biogenesis GTPase MPN656 84 COG1161 COG1161, Predicted GTPases General function prediction only 13507987 Common - Ser/Thr/Tyr protein kinase MPN248 140 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 13508029 Common - hypothetical protein MPN290 19 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 13508004 Common trpS tryptophanyl-tRNA synthetase MPN265 239 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 13507963 Common lgt prolipoprotein diacylglyceryl transferase MPN224 39 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 13508132 Common pdhA Pyruvate dehydrogenase MPN393 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 13507800 Common ffh signal recognition particle protein MPN061 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 13507975 Common - aspartyl/glutamyl-tRNA amidotransferase subunit C-like protein MPN236 5 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 13507844 Common pheS phenylalanyl-tRNA synthetase subunit alpha MPN105 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 13508084 Common hsdR Type I Restriction Enzyme (fragment) MPN345 98 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 13508076 Pathogen - hypothetical protein MPN337 1 None None None 13507768 Common efp elongation factor P MPN029 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 13508041 Common pfkA 6-phosphofructokinase MPN302 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 13507780 Pathogen - hypothetical protein MPN041 1 None None None 13507990 Common cfxE ribulose-phosphate 3-epimerase MPN251 214 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 13507885 Pathogen - hypothetical protein MPN146 1 None None None 13507746 Common holB DNA polymerase III subunit delta' MPN007 118 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair