IslandPathversion 1.0

IslandPath Analysis: Shigella flexneri 2a



Each circle in the graphic corresponds to a predicted protein-coding ORF in the genome. Circle colours indicate if an ORF has a higher or lower %G+C than cutoffs you set below --(default is +/- 3.48 of the mean %G+C). Strike lines across the circles represent regions with dinucleotide bias above a pre-determined cutoff. Click on a circle to view a different portion of the table presented below the graph (default is the first 100 ORFs).
A yellow circle indicates its %G+C value is bigger than the high value. A green circle indicates its %G+C value is bigger than the low value and smaller than the high value. A pink circle indicates its %G+C value is smaller than the low value. A strike line across the circles indicates the region has dinucleotide bais above 1 STD DEV. A black verticle bar indicates a transfer RNA gene lies between the two ORFs. A purple verticle bar indicates a ribosomal RNA gene lies between the two ORFs. A deep blue verticle bar indicates both a tRNA and rRNA gene lie between the two ORFs. A black square indicates the dot is annotated as a transposase. A black triangle indicates the dot is annotated as an integrase. Low: High: Mean: 51.28 STD DEV: 4.24
Shigella flexneri 2a str. 301, complete genome - 0..4607203
4180 proteins

Pos	 %G+C  SD      Location		Strand	Length	PID	Gene	Synonym	Code	Product

1	 51.52         190..255      	 +	21	24111451	thrL	SF0001	-	thr operon leader peptide	
2	 53.21         294..2798     	 +	834	24111452	thrA	SF0002	-	aspartokinase I, homoserine dehydrogenase I	
3	 56.27 +1     2800..3732     	 +	310	24111453	thrB	SF0003	-	homoserine kinase	
4	 52.99        3733..5019     	 +	428	24111454	thrC	SF0004	-	threonine synthase	
5	 54.21        5233..5529     	 +	98	24111455	-	SF0005	-	orf, conserved hypothetical protein	
6	 49.55        5682..6458     	 -	258	24111456	yaaA	SF0006	-	orf, conserved hypothetical protein	
7	 50.18        8074..8358     	 +	94	24111457	-	SF0008	-	orf, hypothetical protein	
8	 51.49        8387..9190     	 +	267	24111458	talB	SF0009	-	Chain A, Crystal Structure Of Escherichia Coli Transaldolase B Mutant D17a	
9	 53.98        9302..9892     	 +	196	24111459	mog	SF0010	-	Mog, required for the efficient incorporation of molybdate into molybdoproteins	
10	 53.26        9927..10493    	 -	188	24111460	yaaH	SF0011	-	orf, conserved hypothetical protein	
11	 50.56       10642..11355    	 -	237	24111461	-	SF0012	-	putative oxidoreductase	
12	 48.40       11381..11785    	 -	134	24111462	yaaI	SF0013	-	orf, conserved hypothetical protein	
13	 51.17       12162..14078    	 +	638	24111463	dnaK	SF0014	-	chaperone Hsp70; DNA biosynthesis; autoregulated heat shock proteins	
14	 54.61       14137..15297    	 +	386	24111464	dnaJ	SF0015	-	chaperone with DnaK; heat shock protein	
15	 51.24       16140..17306    	 +	388	24111465	nhaA	SF0016	-	Na+ H antiporter, pH dependent	
16	 47.29       17348..18271    	 +	307	24111466	nhaR	SF0017	-	transcriptional activator of nhaA	
17	 52.02       18684..19079    	 -	131	24111467	insB	SF0018	-	orf, conserved hypothetical protein	
18	 52.90       19106..19381    	 -	91	24111468	insA	SF0019	-	orf, conserved hypothetical protein	
19	 46.97 -1    19770..20033    	 -	87	24111469	rpsT	SF0020	-	30S ribosomal subunit protein S20	
20	 52.97       20362..21303    	 +	313	24111470	ribF	SF0021	-	putative regulator	
21	 55.70 +1    21346..24162    	 +	938	24111471	ileS	SF0022	-	isoleucine tRNA synthetase	
22	 53.74       24162..24656    	 +	164	24111472	lspA	SF0023	-	prolipoprotein signal peptidase (SPase II)	
23	 54.89       24749..25198    	 -	149	24111473	slpA	SF0024	-	probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase (a rotamase)	
24	 54.89       25256..25705    	 +	149	24111474	slpA	SF0025	-	probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase (a rotamase)	
25	 55.17       25719..26657    	 +	312	24111475	lytB	SF0026	-	control of stringent response; involved in penicillin tolerance	
26	 55.74 +1    26723..27637    	 +	304	24111476	yaaF	SF0027	-	orf, conserved hypothetical protein	
27	 53.04       27804..28625    	 +	273	24111477	dapB	SF0028	-	dihydrodipicolinate reductase	
28	 53.32       29054..30229    	 +	391	24111478	carA	SF0029	-	carbamoyl-phosphate synthetase, glutamine (small) subunit	
29	 55.71 +1    30247..33468    	 +	1073	24111479	carB	SF0030	-	carbamoyl-phosphate synthase large subunit	
30	 43.31 -1    33625..34125    	 +	166	24111480	caiF	SF0031	-	transcriptional regulator of cai operon	
31	 54.41       34211..34822    	 -	203	24111481	caiE	SF0032	-	caiE protein	
32	 52.46       34807..35700    	 -	297	24111482	caiD	SF0033	-	carnitine racemase	
33	 50.73       35701..37269    	 -	522	24111483	caiC	SF0034	-	probable crotonobetaine-carnitine-CoA ligase	
34	 52.46       37328..38545    	 -	405	24111484	caiB	SF0035	-	l-carnitine dehydratase	
35	 53.89       38674..39816    	 -	380	24111485	caiA	SF0036	-	probable carnitine operon oxidoreductase	
36	 52.21       39847..41361    	 -	504	24111486	caiT	SF0037	-	caiT protein	
37	 51.68       41654..42487    	 +	277	24111487	fixA	SF0038	-	probable flavoprotein subunit, carnitine metabolism	
38	 57.07 +1    42502..43293    	 +	263	24111488	fixB	SF0039	-	probable flavoprotein subunit, carnitine metabolism	
39	 55.17       43494..44780    	 +	428	24111489	fixC	SF0040	-	flavoprotein; electron transport	
40	 56.60 +1    44777..45064    	 +	95	24111490	fixX	SF0041	-	putative ferredoxin	
41	 52.26       45123..46517    	 +	464	24111491	yaaU	SF0042	-	putative transport protein	
42	 55.37       46565..47095    	 +	176	24111492	yabF	SF0043	-	putative NAD(P)H oxidoreductase	
43	 55.29       47088..48950    	 +	620	24111493	kefC	SF0044	-	glutathione-regulated K+ efflux antiporter	
44	 52.96       49198..49620    	 +	140	24111494	folA	SF0045	-	dihydrofolate reductase type I; trimethoprim resistance	
45	 55.99 +1    49698..50540    	 -	280	24111495	apaH	SF0046	-	diadenosine tetraphosphatase	
46	 51.85       50547..50924    	 -	125	24111496	apaG	SF0047	-	orf, conserved hypothetical protein	
47	 53.41       50927..51748    	 -	273	24111497	ksgA	SF0048	-	S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase	
48	 56.26 +1    51745..52734    	 -	329	24111498	pdxA	SF0049	-	pyridoxine biosynthesis	
49	 53.85       52734..54020    	 -	428	24111499	surA	SF0050	-	survival protein	
50	 51.38       54073..56427    	 -	784	24111500	imp	SF0051	-	organic solvent tolerance	
51	 52.61       56637..57497    	 +	286	24111501	djlA	SF0052	-	putative DNA binding protein	
52	 54.88       57645..58331    	 -	228	24111502	rluA	SF0053	-	orf, conserved hypothetical protein	
53	 54.90       58286..61192    	 -	968	24111503	hepA	SF0054	-	orf, conserved hypothetical protein	
54	 55.19       61357..63708    	 -	783	24111504	polB	SF0055	-	DNA polymerase II	
55	 55.17       63783..64478    	 -	231	24111505	araD	SF0056	-	L-ribulose-5-phosphate 4-epimerase	
56	 58.08 +1    66190..67890    	 -	566	24111506	araB	SF0058	-	L-ribulokinase	
57	 51.94       68178..69107    	 +	309	24111507	araC	SF0059	-	AraC	
58	 54.51       69193..69957    	 +	254	24111508	yabI	SF0060	-	orf, conserved hypothetical protein	
59	 56.94 +1    70071..70790    	 -	239	24111509	thiQ	SF0061	-	putative ATP-binding component of a transport system	
60	 58.54 +1    70753..72363    	 -	536	24111510	thiP	SF0062	-	putative transport system permease protein	
61	 53.08       72339..73295    	 -	318	24111511	tbpA	SF0063	-	thiamin-binding periplasmic protein	
62	 55.16       73486..75162    	 -	558	24111512	yabN	SF0064	-	putative transport protein	
63	 48.09       75463..76641    	 +	392	24111513	setA	SF0065	-	putative transport protein	
64	 52.15       76690..77295    	 -	201	24111514	leuD	SF0066	-	isopropylmalate isomerase subunit	
65	 55.32       77306..78706    	 -	466	24111515	leuC	SF0067	-	3-isopropylmalate isomerase (dehydratase) subunit	
66	 55.25       78709..79803    	 -	364	24111516	leuB	SF0068	-	3-isopropylmalate dehydrogenase	
67	 52.74       79800..81371    	 -	523	24111517	leuA	SF0069	-	2-isopropylmalate synthase	
68	 47.13       81464..81550    	 -	28	24111518	leuL	SF0070	-	leu operon leader peptide	
69	 43.76 -1    82032..83153    	 +	373	24111519	leuO	SF0071	-	probable transcriptional activator for leuABCD operon	
70	 52.79       83495..85195    	 +	566	24111520	ilvI	SF0072	-	acetolactate synthase III large chain	
71	 49.81       85168..85689    	 +	173	24111521	ilvH	SF0073	-	acetolactate synthase III, valine sensitive, small subunit	
72	 47.13       85701..85787    	 +	28	24111522	fruL	SF0074	-	fruR leader peptide	
73	 54.93       85869..86873    	 +	334	24111523	fruR	SF0075	-	transcriptional repressor of fru operon and others	
74	 52.90       86996..87271    	 +	91	24111524	insA	SF0076	-	orf, conserved hypothetical protein	
75	 52.27       87298..87693    	 +	131	24111525	insB	SF0077	-	orf, conserved hypothetical protein	
76	 52.53       88216..88710    	 +	164	24111526	yabB	SF0078	-	orf, conserved hypothetical protein	
77	 55.20       88712..89653    	 +	313	24111527	yabC	SF0079	-	yabC protein	
78	 50.55       89650..90015    	 +	121	24111528	ftsL	SF0080	-	cell division protein; ingrowth of wall at septum	
79	 53.82       90031..91797    	 +	588	24111529	ftsI	SF0081	-	septum formation; penicillin-binding protein 3; peptidoglycan synthetase	
80	 56.79 +1    91784..93271    	 +	495	24111530	murE	SF0082	-	UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase	
81	 54.82       93268..94626    	 +	452	24111531	murF	SF0083	-	D-alanine:D-alanine-adding enzyme	
82	 52.82       94620..95702    	 +	360	24111532	mraY	SF0084	-	phospho-N-acetylmuramoyl-pentapeptide transferase?	
83	 55.28       95705..97021    	 +	438	24111533	murD	SF0085	-	UDP-N-acetylmuramoylalanine-D-glutamate ligase	
84	 52.48       97018..98265    	 +	415	24111534	ftsW	SF0086	-	cell division, membrane protein involved in shape determination	
85	 55.71 +1    98262..99329    	 +	355	24111535	murG	SF0087	-	UDP-N-acetylglucosamine:N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	
86	 54.40       99383..100858   	 +	491	24111536	murC	SF0088	-	UDP-N-acetyl-muramate:alanine ligase, L-alanine adding enzyme	
87	 51.47      100851..101771   	 +	306	24111537	ddlB	SF0089	-	D-alanine-D-alanine ligase B, affects cell division	
88	 53.31      101773..102603   	 +	276	24111538	ftsQ	SF0090	-	cell division protein; ingrowth of wall at septum	
89	 52.02      102600..103862   	 +	420	24111539	ftsA	SF0091	-	ATP-binding cell division protein, septation process, complexes with FtsZ, associated with junctions of inner and outer membranes	
90	 54.31      104007..105074   	 +	355	24111540	ftsZ	SF0092	-	tubulin-like GTP-binding protein and GTPase; cell division; forms circumferential ring	
91	 51.20      105175..106092   	 +	305	24111541	lpxC	SF0093	-	UDP-3-O-acyl N-acetylglucosamine deacetylase; lipid A biosynthesis	
92	 50.15      106170..106835   	 +	221	24111542	yacA	SF0094	-	orf, conserved hypothetical protein	
93	 52.25      106897..109602   	 +	901	24111543	secA	SF0095	-	preprotein translocase; secretion protein	
94	 49.23      109662..110051   	 +	129	24111544	mutT	SF0096	-	7,8-dihydro-8-oxoguanine-triphosphatase; prefers dGTP, causes AT-GC transversions	
95	 54.81      110066..110200   	 -	44	24111545	-	SF0097	-	orf, conserved hypothetical protein	
96	 52.02      110151..110348   	 -	65	24111546	yacG	SF0098	-	orf, conserved hypothetical protein	
97	 51.21      110358..111101   	 -	247	24111547	yacF	SF0099	-	orf, conserved hypothetical protein	
98	 52.33      111101..111721   	 -	206	24111548	yacE	SF0100	-	putative DNA repair protein	
99	 51.72      111946..112989   	 +	347	24111549	guaC	SF0101	-	GMP reductase	
100	 51.85      112909..113016   	 -	35	24111550	-	SF0102	-	orf, conserved hypothetical protein	

 
 51.28 MEAN 
 
 4.24  STD DEV 



Last Updated: Sept 17 2004 (Note: update adds new organisms but does not affect the existing records)

Funding for this work was provided by the Peter Wall Institute for Advanced Studies. This service is hosted by the Brinkman Laboratory of the Department of Molecular Biology and Biochemistry at Simon Fraser University.