IslandPathversion 1.0

IslandPath Analysis: Neisseria meningitidis serogroup B strain MC58



Each circle in the graphic corresponds to a predicted protein-coding ORF in the genome. Circle colours indicate if an ORF has a higher or lower %G+C than cutoffs you set below --(default is +/- 3.48 of the mean %G+C). Strike lines across the circles represent regions with dinucleotide bias above a pre-determined cutoff. Click on a circle to view a different portion of the table presented below the graph (default is the first 100 ORFs).
A yellow circle indicates its %G+C value is bigger than the high value. A green circle indicates its %G+C value is bigger than the low value and smaller than the high value. A pink circle indicates its %G+C value is smaller than the low value. A strike line across the circles indicates the region has dinucleotide bais above 1 STD DEV. A black verticle bar indicates a transfer RNA gene lies between the two ORFs. A purple verticle bar indicates a ribosomal RNA gene lies between the two ORFs. A deep blue verticle bar indicates both a tRNA and rRNA gene lie between the two ORFs. A black square indicates the dot is annotated as a transposase. A black triangle indicates the dot is annotated as an integrase. Low: High: Mean: 51.34 STD DEV: 7.57
Neisseria meningitidis serogroup B strain MC58 complete genome - 0..2272351
2079 proteins

Pos	 %G+C  SD      Location		Strand	Length	PID	Gene	Synonym	Code	Product

1	 48.58           7..498      	 -	163	15675949	NMB0001	NMB0001	K	acetyltransferase, putative	
2	 49.24         502..897      	 -	131	15675950	NMB0002	NMB0002	-	hypothetical protein	
3	 53.91         918..2312     	 -	464	15675951	NMB0003	NMB0003	J	glutamyl-tRNA synthetase	
4	 54.88        2517..3161     	 -	214	15675952	NMB0004	NMB0004	S	EpiH/GdmH-related protein	
5	 51.69        3158..3511     	 -	117	15675953	NMB0005	NMB0005	P	arsenate reductase	
6	 53.83        3635..4117     	 +	160	15675954	NMB0006	NMB0006	O	thioredoxin-related protein	
7	 55.45        4311..4961     	 +	216	15675955	NMB0007	NMB0007	D	cell division ATP-binding protein FtsE	
8	 56.21        4958..5875     	 +	305	15675956	NMB0008	NMB0008	D	cell division protein FtsX, putative	
9	 51.41        5966..6214     	 +	82	15675957	NMB0009	NMB0009	T	BolA/YrbA family protein	
10	 58.17        6281..7492     	 -	403	15675958	NMB0010	NMB0010	G	phosphoglycerate kinase	
11	 58.77        7573..8826     	 -	417	15675959	NMB0011	NMB0011	M	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	
12	 50.10        9346..10317    	 -	323	15675960	NMB0012	NMB0012	P	conserved hypothetical protein	
13	 53.56       10350..10799    	 -	149	15675961	NMB0013	NMB0013	S	conserved hypothetical protein	
14	 59.67 +1    10840..12111    	 -	423	15675962	NMB0014	NMB0014	M	3-deoxy-D-manno-octulosonic-acid transferase	
15	 53.83       12174..13622    	 -	482	15675963	NMB0015	NMB0015	G	6-phosphogluconate dehydrogenase, decarboxylating	
16	 42.62 -1    13918..14154    	 +	78	15675964	NMB0016	NMB0016	-	hypothetical protein	
17	 53.90       15221..16144    	 -	307	15675965	NMB0017	NMB0017	M	UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase	
18	 52.24       17229..17741    	 -	170	15675966	NMB0018	NMB0018	N	pilin PilE	
19	 52.25       18517..18939    	 -	140	15677974	-	NMB0019	N	pilS cassette	
20	 52.97       19267..19653    	 -	128	15677975	-	NMB0020	N	pilS cassette	
21	 52.20       19918..20304    	 -	128	15677976	-	NMB0021	N	pilS cassette	
22	 51.65       20832..21164    	 -	110	15677977	-	NMB0022	N	pilS cassette	
23	 52.14       21470..21889    	 -	139	15677978	-	NMB0023	N	pilS cassette	
24	 50.08       21891..22481    	 -	196	15677979	-	NMB0024	N	pilS cassette	
25	 53.27       22825..23496    	 -	223	15677980	-	NMB0025	N	large pilS cassette	
26	 57.18       23528..23875    	 -	115	15677981	-	NMB0026	N	pilS cassette	
27	 55.45       23904..24233    	 -	109	15675967	NMB0027	NMB0027	O	FKBP-type peptidyl-prolyl cis-trans isomerase	
28	 46.58       24311..24529    	 -	72	15675968	NMB0028	NMB0028	S	hypothetical protein	
29	 53.04       24651..25604    	 +	317	15675969	NMB0029	NMB0029	C	glycerate dehydrogenase	
30	 54.28       25679..27736    	 -	685	15675970	NMB0030	NMB0030	R	methionyl-tRNA synthetase	
31	 57.37       27852..29690    	 -	612	15675971	NMB0031	NMB0031	M	glucosamine--fructose-6-phosphate aminotransferase (isomerizing)	
32	 49.62       29966..30493    	 +	175	15675972	NMB0032	NMB0032	-	hypothetical protein	
33	 59.05 +1    30911..32236    	 -	441	15675973	NMB0033	NMB0033	M	membrane-bound lytic murein transglycosylase A, putative	
34	 55.60       32447..33286    	 +	279	15675974	NMB0034	NMB0034	P	conserved hypothetical protein	
35	 53.73       33283..34449    	 +	388	15675975	NMB0035	NMB0035	P	conserved hypothetical protein	
36	 58.69       34713..35978    	 +	421	15675976	NMB0036	NMB0036	P	conserved hypothetical protein	
37	 52.42       36050..36379    	 -	109	15675977	NMB0037	NMB0037	P	phnA protein	
38	 57.33       36454..37824    	 -	456	15675978	NMB0038	NMB0038	M	UDP-N-acetylglucosamine pyrophosphorylase	
39	 53.11       37879..38151    	 -	90	15675979	NMB0039	NMB0039	-	hypothetical protein	
40	 55.60       38144..38857    	 -	237	15675980	NMB0040	NMB0040	R	hydrolase, putative	
41	 59.58 +1    38916..39917    	 +	333	15675981	NMB0041	NMB0041	H	ABC transporter, periplasmic solute-binding protein	
42	 53.36       40011..40859    	 +	282	15675982	NMB0042	NMB0042	M	conserved hypothetical protein	
43	 61.11 +1    40885..41370    	 +	161	15675983	NMB0043	NMB0043	R	conserved hypothetical protein	
44	 54.75       41472..43040    	 -	522	15675984	NMB0044	NMB0044	O	peptide methionine sulfoxide reductase	
45	 55.85       43186..44451    	 +	421	15675985	NMB0045	NMB0045	N	signal recognition particle protein	
46	 51.56       44458..44682    	 +	74	15675986	NMB0046	NMB0046	-	hypothetical protein	
47	 39.30 -1    45079..45363    	 +	94	15675987	NMB0047	NMB0047	L	conserved hypothetical protein	
48	 57.64       47976..48119    	 +	47	15677982	-	NMB0048	-	conserved hypothetical protein	
49	 60.44 +1    53030..55180    	 -	716	15675988	NMB0050	NMB0050	S	conserved hypothetical protein	
50	 55.91       55466..56692    	 -	408	15675989	NMB0051	NMB0051	N	twitching motility protein	
51	 56.80       56855..57898    	 -	347	15675990	NMB0052	NMB0052	N	twitching motility protein PilT	
52	 56.91       58018..58704    	 +	228	15675991	NMB0053	NMB0053	R	conserved hypothetical protein	
53	 53.19       58704..59111    	 +	135	15675992	NMB0054	NMB0054	-	hypothetical protein	
54	 53.54       59160..59951    	 +	263	15675993	NMB0055	NMB0055	E	pyrroline-5-carboxylate reductase	
55	 49.88       60098..60514    	 +	138	15675994	NMB0056	NMB0056	T	DnaK suppressor protein	
56	 54.06       66354..66710    	 +	118	15675995	NMB0057	NMB0057	L	hypothetical protein	
57	 42.14 -1    66739..66897    	 +	52	15675996	NMB0058	NMB0058	-	hypothetical protein	
58	 53.21       66979..68100    	 +	373	15675997	NMB0059	NMB0059	O	dnaJ protein	
59	 54.53       68296..70314    	 +	672	15675998	NMB0060	NMB0060	S	conserved hypothetical protein	
60	 53.06       70969..71835    	 -	288	15675999	NMB0062	NMB0062	M	glucose-1-phosphate thymidylyltransferase	
61	 53.46       71898..72965    	 -	355	15676000	NMB0063	NMB0063	M	dTDP-D-glucose 4,6-dehydratase	
62	 50.88       73081..74100    	 -	339	15676001	NMB0064	NMB0064	M	UDP-glucose 4-epimerase	
63	 34.63 -2    74483..75409    	 +	308	15676002	NMB0065	NMB0065	-	hypothetical protein	
64	 25.71 -2    75694..76428    	 +	244	15676003	NMB0066	NMB0066	J	rRNA adenine N-6-methyltransferase; foreign cassette inserted to disrupt SiaD (NMB0067) to reduce virulence	
65	 29.06 -2    76613..77290    	 -	225	15677983	-	NMB0067	-	polysialic acid capsule biosynthesis protein SiaD; disrupted by foreign ermC (NMB0066) cassette	
66	 40.76 -1    77374..78423    	 -	349	15676004	NMB0068	NMB0068	M	polysialic acid capsule biosynthesis protein SiaC	
67	 40.17 -1    78424..79110    	 -	228	15676005	NMB0069	NMB0069	M	polysialic acid capsule biosynthesis protein SiaB	
68	 38.01 -1    79114..80247    	 -	377	15676006	NMB0070	NMB0070	M	polysialic acid capsule biosynthesis protein SynX	
69	 46.68       80382..81557    	 +	391	15676007	NMB0071	NMB0071	M	capsule polysaccharide export outer membrane protein CtrA	
70	 46.99       81572..82735    	 +	387	15676008	NMB0072	NMB0072	M	capsule polysaccharide export inner-membrane protein CtrB	
71	 42.98 -1    82735..83532    	 +	265	15676009	NMB0073	NMB0073	M	capsule polysaccharide export inner-membrane protein CtrC	
72	 47.16       83529..84179    	 +	216	15676010	NMB0074	NMB0074	G	capsule polysaccharide export ATP-binding protein CtrD	
73	 59.45 +1    84243..86516    	 +	757	15676011	NMB0075	NMB0075	R	transcriptional accessory protein Tex, putative	
74	 36.75 -1    87536..87886    	 +	116	15677984	-	NMB0077	-	site-specific DNA methylase	
75	 51.75       87929..88585    	 +	218	15677985	-	NMB0078	M	UDP-glucose 4-epimerase	
76	 53.46       88701..89768    	 +	355	15676012	NMB0079	NMB0079	M	dTDP-D-glucose 4,6-dehydratase	
77	 53.06       89831..90697    	 +	288	15676013	NMB0080	NMB0080	M	glucose-1-phosphate thymidylyltransferase	
78	 50.81       90736..91290    	 +	184	15676014	NMB0081	NMB0081	M	dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase	
79	 51.82       91315..93429    	 +	704	15676015	NMB0082	NMB0082	M	capsule polysaccharide modification protein LipA	
80	 48.97       93566..94825    	 +	419	15676016	NMB0083	NMB0083	M	capsule polysaccharide modification protein LipB	
81	 53.33       96815..98029    	 +	404	15676017	NMB0085	NMB0085	E	sodium/glutamate symporter	
82	 58.01       98128..99144    	 +	338	15676018	NMB0086	NMB0086	-	hypothetical protein	
83	 51.52       99155..99352    	 +	65	15676019	NMB0087	NMB0087	-	hypothetical protein	
84	 56.67       99777..101177   	 -	466	15676020	NMB0088	NMB0088	I	outer membrane protein P1, putative	
85	 60.01 +1   101492..102964   	 -	490	15676021	NMB0089	NMB0089	G	pyruvate kinase II	
86	 38.40 -1   104406..104642   	 +	78	15676022	NMB0091	NMB0091	-	hypothetical protein	
87	 33.77 -2   104636..104863   	 +	75	15676023	NMB0092	NMB0092	-	hypothetical protein	
88	 26.44 -2   104863..104949   	 +	28	15676024	NMB0093	NMB0093	-	hypothetical protein	
89	 22.75 -2   105235..105423   	 +	62	15676025	NMB0094	NMB0094	-	hypothetical protein	
90	 46.41      105430..105582   	 +	50	15676026	NMB0095	NMB0095	-	hypothetical protein	
91	 24.56 -2   105683..105853   	 +	56	15676027	NMB0096	NMB0096	-	hypothetical protein	
92	 38.19 -1   109488..109631   	 -	47	15676028	NMB0099	NMB0099	-	hypothetical protein	
93	 34.69 -2   109631..109777   	 -	48	15676029	NMB0100	NMB0100	-	hypothetical protein	
94	 60.31 +1   110615..111133   	 +	172	15676030	NMB0102	NMB0102	-	hypothetical protein	
95	 38.59 -1   111409..111903   	 -	164	15676031	NMB0103	NMB0103	R	bacteriocin resistance protein, putative	
96	 39.70 -1   112406..113080   	 -	224	15676032	NMB0104	NMB0104	-	hypothetical protein	
97	 57.53      113362..114204   	 -	280	15676033	NMB0105	NMB0105	K	PhnO-related protein	
98	 56.57      114443..115363   	 +	306	15676034	NMB0106	NMB0106	F	aspartate carbamoyltransferase, catalytic subunit	
99	 56.21      115373..115831   	 +	152	15676035	NMB0107	NMB0107	F	aspartate carbamoyltransferase, regulatory subunit	
100	 53.30      115896..116561   	 +	221	15676036	NMB0108	NMB0108	-	hypothetical protein	

 
 51.34 MEAN 
 
 7.57  STD DEV 



Last Updated: Sept 17 2004 (Note: update adds new organisms but does not affect the existing records)

Funding for this work was provided by the Peter Wall Institute for Advanced Studies. This service is hosted by the Brinkman Laboratory of the Department of Molecular Biology and Biochemistry at Simon Fraser University.