IslandPath Analysis: Mycobacterium leprae



Each circle in the graphic corresponds to a predicted protein-coding ORF in the genome.
Circle colours indicate if an ORF has a higher or lower %G+C than cutoffs you set below
--(default is +/- 3.48 of the mean %G+C).
Strike lines across the circles represent regions with dinucleotide bias above a pre-determined cutoff.
Click on a circle to view a different portion of the table presented below the graph (default is the first 100 ORFs).




A yellow circle indicates its %G+C value is bigger than the high value.
A green circle indicates its %G+C value is bigger than the low value and smaller than the high value.
A pink circle indicates its %G+C value is smaller than the low value.

A strike line across the circles indicates the region has dinucleotide bais above 1 STD DEV.
A black verticle bar indicates a transfer RNA gene lies between the two ORFs.
A purple verticle bar indicates a ribosomal RNA gene lies between the two ORFs.
A deep blue verticle bar indicates both a tRNA and rRNA gene lie between the two ORFs.
A black square indicates the dot is annotated as a transposase.
A black triangle indicates the dot is annotated as an integrase.


Low:  High:    Mean: 59.70   STD DEV: 3.21
Mycobacterium leprae strain TN complete genome - 0..3268203
1605 proteins

Pos	 %G+C  SD      Location		Strand	Length	PID	Gene	Synonym	Code	Product

1	 53.64 -1        1..1566     	 +	521	15826866	dnaA	ML0001	L	putative chromosomal replication initiator protein	
2	 54.08 -1     2081..3280     	 +	399	15826867	dnaN	ML0002	L	putative DNA polymerase III, [beta] subunit	
3	 53.80 -1     3281..4438     	 +	385	15826868	recF	ML0003	L	putative DNA replication and SOS induction protein	
4	 57.19        4435..5004     	 +	189	15826869	-	ML0004	-	conserved hypothetical protein	
5	 50.47 -2     5229..7265     	 +	678	15826870	gyrB	ML0005	L	putative DNA gyrase subunit B	
6	 52.19 -2     7318..11067    	 +	1249	15826871	gyrA	ML0006	L	putative DNA gyrase subunit A	
7	 56.47 -1    11195..12106    	 +	303	15826872	-	ML0007	-	putative membrane protein	
8	 46.93 -2    12856..13230    	 -	124	15826873	-	ML0008	-	hypothetical protein	
9	 43.23 -2    13775..13966    	 +	63	15826874	-	ML0009	-	hypothetical protein	
10	 56.10 -1    15993..16541    	 +	182	15826875	ppiA	ML0011	O	putative peptidyl-prolyl cis-trans isomerase	
11	 56.52       16566..16979    	 -	137	15826876	-	ML0012	-	putative membrane protein	
12	 57.45       17134..17415    	 -	93	15826877	-	ML0013	-	conserved hypothetical protein	
13	 57.80       18325..19023    	 +	232	15826878	pabA	ML0015	E	putative p-aminobenzoate synthase glutamine amidotransferase	
14	 58.75       19001..20869    	 -	622	15826879	pknB	ML0016	S	putative serine/threonine protein kinase	
15	 60.58       20879..22192    	 -	437	15826880	pknA	ML0017	T	putative serine/threonine protein kinase	
16	 61.33       22189..23667    	 -	492	15826881	pbpA	ML0018	M	putative penicillin-binding protein	
17	 56.58       23664..25061    	 -	465	15826882	rodA	ML0019	D	putative cell-division protein	
18	 60.92       25058..26587    	 -	509	15826883	-	ML0020	T	conserved hypothetical protein	
19	 57.48       26584..27051    	 -	155	15826884	-	ML0021	T	conserved hypothetical protein	
20	 61.28       27173..28639    	 -	488	15826885	-	ML0022	T	conserved hypothetical protein	
21	 56.09 -1    28954..29265    	 -	103	15826886	-	ML0023	-	hypothetical protein	
22	 51.98 -2    29775..30026    	 +	83	15826887	-	ML0024	-	hypothetical protein	
23	 60.14       30293..30583    	 -	96	15826888	-	ML0025	-	hypothetical protein	
24	 59.08       33100..33705    	 +	201	15826889	-	ML0028	K	conserved hypothetical protein	
25	 56.44 -1    34033..34638    	 -	201	15826890	-	ML0029	R	possible membrane protein	
26	 64.62 +1    34750..35091    	 -	113	15826891	-	ML0030	-	putative membrane protein	
27	 60.81       35287..36123    	 -	278	15826892	-	ML0031	-	Similar to M. tuberculosis MTC28, Rv0040c, proline rich 28 KDa antigen precursoR, SW:PR28_MYCTU (P71697) (311 aa); Fasta score E(): 0, 65.1% identity in 258 aa overlap. Previously sequenced as TR:O33075 (EMBL:Y14967) (278 aa); Fasta score E(): 0, 100.0% identity in 278 aa overlap. Contains a probable N-terminal signal sequence.~C-terminal half is similar to a region of ML0246	
28	 58.82       36321..39239    	 +	972	15826893	leuS	ML0032	J	leucyl-tRNA synthase	
29	 60.85       50656..51996    	 +	446	15826894	-	ML0041	O	probable secreted protease	
30	 59.26       51993..53396    	 +	467	15826895	-	ML0042	-	putative membrane protein	
31	 55.85 -1    54698..55039    	 +	113	15826896	-	ML0044	-	Similar to M. tuberculosis Rv3880c, hypothetical protein, TR:O69744 (EMBL:AL123456) (115 aa); Fasta score E(): 2.6e-21, 56.4% identity in 110 aa overlap. Previously sequenced as TR:O33080 (EMBL:Y14967) (113 aa); Fasta score E(): 0, 100.0% identity in 113 aa overlap.	
32	 60.43       58020..59558    	 -	512	15826897	-	ML0047	-	putative membrane protein	
33	 59.68       59555..61315    	 -	586	15826898	-	ML0048	D	conserved hypothetical protein	
34	 54.17 -1    61406..61693    	 -	95	15826899	-	ML0049	-	possible secreted protein	
35	 56.44 -1    61720..62022    	 -	100	15826900	-	ML0050	-	possible secreted protein	
36	 58.97       62201..63109    	 -	302	15826901	-	ML0051	-	PPE-family protein	
37	 59.48       63319..65112    	 -	597	15826902	-	ML0052	D	conserved hypothetical protein	
38	 59.46       65186..67420    	 -	744	15826903	-	ML0053	D	putative membrane protein	
39	 58.78       67417..68862    	 -	481	15826904	-	ML0054	-	putative membrane protein	
40	 59.41       68866..70587    	 -	573	15826905	-	ML0055	O	conserved hypothetical protein	
41	 55.10 -1    70584..71093    	 -	169	15826906	-	ML0056	-	conserved hypothetical protein	
42	 58.49       77709..82292    	 +	1527	15826907	gltB	ML0061	E	putative ferredoxin-dependent glutamate synthase	
43	 60.05       82285..83751    	 +	488	15826908	gltD	ML0062	E	NADH-dependent glutamate synthase small subunit	
44	 55.81 -1    85968..86612    	 -	214	15826909	-	ML0064	K	putative transcriptional regulator	
45	 54.48 -1    86681..88165    	 +	494	15826910	-	ML0065	P	putative monooxygenase	
46	 60.97       88246..88719    	 -	157	15826911	menG	ML0066	H	putative S-adenosylmethionine:2-demethylmenaquinone methyltransferase	
47	 56.83       88741..89106    	 -	121	15826912	hns	ML0067	-	histone-like protein	
48	 60.81       89620..90336    	 -	238	15826913	-	ML0068	-	conserved hypothetical protein	
49	 59.40       90521..90919    	 -	132	15826914	-	ML0069	-	conserved hypothetical protein	
50	 60.98       91296..91559    	 -	87	15826915	-	ML0070	-	hypothetical protein	
51	 58.24       91913..92446    	 -	177	15826916	-	ML0071	-	conserved hypothetical protein	
52	 53.85 -1    92647..93270    	 -	207	15826917	sodA	ML0072	P	superoxide dismutase	
53	 60.68       94092..95126    	 +	344	15826918	-	ML0073	-	putative membrane protein	
54	 61.76       95132..95947    	 +	271	15826919	glpQ	ML0074	C	putative glycerophosphoryl diester phosphodiesterase	
55	 65.22 +1    98425..99393    	 +	322	15826920	pheA	ML0078	E	putative prephenate dehydratase	
56	 60.06       99390..100085   	 +	231	15826921	-	ML0079	G	putative phosphoglycerate mutase	
57	 61.79      100648..102000   	 -	450	15826922	-	ML0081	-	putative membrane protein	
58	 61.96      102122..103375   	 +	417	15826923	serS	ML0082	J	putative seryl-tRNA synthase	
59	 59.69      109049..109822   	 +	257	15826924	-	ML0087	I	putative acyltransferase	
60	 64.42 +1   110329..111174   	 +	281	15826925	-	ML0089	R	conserved hypothetical protein	
61	 59.63      113153..113863   	 -	236	15826926	-	ML0091	-	28 KDa antigen precursor	
62	 57.97      114130..115371   	 +	413	15826927	glf	ML0092	M	putative UDP-galactopyranose mutase	
63	 59.32      115371..117302   	 +	643	15826928	-	ML0093	-	conserved hypothetical protein	
64	 62.18      117295..117873   	 +	192	15826929	-	ML0094	I	putative membrane protein	
65	 59.19      117870..118778   	 +	302	15826930	-	ML0095	H	putative integral membrane protein	
66	 60.56      118819..120768   	 +	649	15826931	-	ML0096	-	putative membrane protein	
67	 60.52      121157..122149   	 +	330	15826932	fbpA	ML0097	R	antigen 85A, mycolytransferase	
68	 63.69 +1   122310..123215   	 +	301	15826933	fbpC	ML0098	R	antigen 85C, mycolyltransferase	
69	 59.94      123370..124380   	 +	336	15826934	-	ML0099	-	conserved hypothetical protein	
70	 61.37      124599..126506   	 +	635	15826935	fadD32	ML0100	I	putative acyl-CoA synthetase	
71	 60.80      126518..131872   	 +	1784	15826936	pks13	ML0101	Q	polyketide synthase	
72	 59.20      131869..133422   	 +	517	15826937	accD4	ML0102	I	putative acyl CoA carboxylase [beta] subunit	
73	 60.85      136573..139824   	 -	1083	15826938	embB	ML0104	-	putative arabinosyl transferase	
74	 62.77      139821..143156   	 -	1111	15826939	embA	ML0105	-	putative arabinosyl transferase	
75	 61.81      144115..147327   	 -	1070	15826940	embC	ML0106	-	putative arabinosyl transferase	
76	 62.66      147460..149358   	 -	632	15826941	-	ML0107	-	putative membrane protein	
77	 58.56      149361..150125   	 -	254	15826942	-	ML0108	Q	putative oxidoreductase	
78	 59.07      150128..151510   	 -	460	15826943	-	ML0109	C	putative FAD-linked oxidoreductase	
79	 56.45 -1   151578..151949   	 -	123	15826944	-	ML0110	S	possible membrane protein	
80	 56.56      152783..153613   	 -	276	15826945	-	ML0112	M	putative ABC transporter component	
81	 59.62      153663..154514   	 -	283	15826946	rfbE	ML0113	R	putative glycosyl transferase	
82	 59.34      154576..155394   	 -	272	15826947	-	ML0114	G	putative ABC transporter ATP-binding component	
83	 62.10      155413..155937   	 -	174	15826948	-	ML0115	-	conserved hypothetical protein	
84	 60.41      155965..157929   	 -	654	15826949	-	ML0116	-	putative membrane protein	
85	 61.82      158056..159252   	 +	398	15826950	-	ML0117	E	conserved hypothetical protein	
86	 61.82      159249..160259   	 -	336	15826951	-	ML0118	C	putative oxidireductase	
87	 61.08      160495..161730   	 -	411	15826952	lipE	ML0119	M	probable hydrolase	
88	 61.17      161741..162577   	 -	278	15826953	echA1	ML0120	I	putative enoyl-CoA hydratase	
89	 54.81 -1   163770..164039   	 -	89	15826954	-	ML0121	-	hypothetical protein	
90	 54.42 -1   166949..167389   	 -	146	15826955	-	ML0124	-	conserved hypothetical protein	
91	 60.14      167598..168914   	 +	438	15826956	-	ML0125	G	putative glycosyl transferase	
92	 57.30      169585..170406   	 +	273	15826957	-	ML0126	-	hypothetical protein	
93	 48.99 -2   170662..171351   	 +	229	15826958	-	ML0127	Q	hypothetical protein	
94	 59.40      171616..172923   	 +	435	15826959	-	ML0128	G	putative glycosyl transferase	
95	 59.67      173170..174426   	 -	418	15826960	-	ML0129	S	conserved hypothetical protein	
96	 55.97 -1   174466..175278   	 -	270	15826961	-	ML0130	Q	conserved hypothetical protein	
97	 57.18      175441..176589   	 +	382	15826962	-	ML0131	C	putative oxidoreductase	
98	 56.09 -1   177170..179212   	 +	680	15826963	fadD29	ML0132	I	putative acyl-CoA synthetase	
99	 46.13 -2   179256..179888   	 +	210	15826964	-	ML0133	H	conserved hypothetical protein	
100	 57.16      180027..182150   	 +	707	15826965	fadD22	ML0134	I	putative acyl-CoA synthetase	

 
 59.70 MEAN 
 
 3.21  STD DEV 




Last Updated: Sept 17 2004 (Note: update adds new organisms but does not affect the existing records)
      
Funding for this work was provided by the Peter Wall Institute for Advanced Studies. This service is hosted by the Brinkman Laboratory of the Department of Molecular Biology and Biochemistry at Simon Fraser University.