IslandPathversion 1.0

IslandPath Analysis: Escherichia coli O157_EDL933



Each circle in the graphic corresponds to a predicted protein-coding ORF in the genome. Circle colours indicate if an ORF has a higher or lower %G+C than cutoffs you set below --(default is +/- 3.48 of the mean %G+C). Strike lines across the circles represent regions with dinucleotide bias above a pre-determined cutoff. Click on a circle to view a different portion of the table presented below the graph (default is the first 100 ORFs).
A yellow circle indicates its %G+C value is bigger than the high value. A green circle indicates its %G+C value is bigger than the low value and smaller than the high value. A pink circle indicates its %G+C value is smaller than the low value. A strike line across the circles indicates the region has dinucleotide bais above 1 STD DEV. A black verticle bar indicates a transfer RNA gene lies between the two ORFs. A purple verticle bar indicates a ribosomal RNA gene lies between the two ORFs. A deep blue verticle bar indicates both a tRNA and rRNA gene lie between the two ORFs. A black square indicates the dot is annotated as a transposase. A black triangle indicates the dot is annotated as an integrase. Low: High: Mean: 50.36 STD DEV: 5.88
Escherichia coli O157:H7 EDL933, complete genome - 0..5528445
5324 proteins

Pos	 %G+C  SD      Location		Strand	Length	PID	Gene	Synonym	Code	Product

1	 51.19         190..273      	 +	27	15799681	thrL	Z0001	-	thr operon leader peptide	
2	 52.82         354..2816     	 +	820	15799682	thrA	Z0002	E	aspartokinase I, homoserine dehydrogenase I	
3	 56.27 +1     2818..3750     	 +	310	15799683	thrB	Z0003	E	homoserine kinase	
4	 53.15        3751..5037     	 +	428	15799684	thrC	Z0004	E	threonine synthase	
5	 53.87        5251..5547     	 +	98	15799685	-	Z0005	-	orf, hypothetical protein	
6	 48.91        5700..6476     	 -	258	15799686	yaaA	Z0006	S	orf, hypothetical protein	
7	 52.97        6546..7976     	 -	476	15799687	yaaJ	Z0007	E	inner membrane transport protein	
8	 51.68        8255..9208     	 +	317	15799688	talB	Z0008	G	transaldolase B	
9	 53.91        9323..9910     	 +	195	15799689	mog	Z0009	H	required for the efficient incorporation of molybdate into molybdoproteins	
10	 52.73        9945..10511    	 -	188	15799690	yaaH	Z0010	R	orf, hypothetical protein	
11	 50.98       10660..11373    	 -	237	15799691	-	Z0011	-	putative oxidoreductase	
12	 50.08       10742..11362    	 +	206	15799692	htgA	Z0012	-	positive regulator for sigma 32 heat shock promoters	
13	 48.89       11399..11803    	 -	134	15799693	yaaI	Z0013	-	orf, hypothetical protein	
14	 51.38       12180..14096    	 +	638	15799694	dnaK	Z0014	O	chaperone Hsp70; DNA biosynthesis; autoregulated heat shock proteins	
15	 55.08       14185..15315    	 +	376	15799695	dnaJ	Z0015	O	chaperone with DnaK; heat shock protein	
16	 50.48       15419..15628    	 -	69	15799696	gef	Z0016	-	Gef protein interferes with membrane function when in excess	
17	 51.33       16157..17323    	 +	388	15799697	nhaA	Z0018	P	Na+/H antiporter, pH dependent	
18	 47.57       17383..18288    	 +	301	15799698	nhaR	Z0019	K	transcriptional activator of nhaA	
19	 37.34 -2    18326..18949    	 -	207	15799699	-	Z0020	-	-	
20	 37.00 -2    18960..19286    	 -	108	15799700	-	Z0021	-	-	
21	 41.00 -1    19299..21749    	 -	816	15799701	-	Z0022	N	putative usher protein	
22	 36.55 -2    21762..22445    	 -	227	15799702	-	Z0023	N	putative chaperone protein	
23	 39.14 -1    22495..23028    	 -	177	15799703	-	Z0024	-	putative type-1 fimbrial protein	
24	 32.28 -2    23330..24751    	 -	473	15799704	-	Z0025	-	-	
25	 46.59       25221..25484    	 -	87	15799705	rpsT	Z0027	J	30S ribosomal subunit protein S20	
26	 48.00       25587..25811    	 +	74	15799706	-	Z0028	-	orf, hypothetical protein	
27	 53.50       25819..26760    	 +	313	15799707	ribF	Z0029	H	putative regulator	
28	 55.70       26803..29619    	 +	938	15799708	ileS	Z0030	J	isoleucine tRNA synthetase	
29	 53.33       29619..30113    	 +	164	15799709	lspA	Z0031	N	prolipoprotein signal peptidase (SPase II)	
30	 55.33       30201..30650    	 +	149	15799710	slpA	Z0033	O	probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase (a rotamase)	
31	 55.21       30652..31602    	 +	316	15799711	lytB	Z0034	I	control of stringent response; involved in penicillin tolerance	
32	 55.63       31668..32582    	 +	304	15799712	yaaF	Z0035	F	orf, hypothetical protein	
33	 52.92       32749..33570    	 +	273	15799713	dapB	Z0036	E	dihydrodipicolinate reductase	
34	 53.44       34026..35174    	 +	382	15799714	carA	Z0037	E	carbamoyl-phosphate synthetase, glutamine (small) subunit	
35	 55.87       35192..38413    	 +	1073	15799715	carB	Z0038	E	carbamoyl-phosphate synthase large subunit	
36	 35.62 -2    38421..38639    	 -	72	15799716	-	Z0039	-	-	
37	 43.51 -1    38569..39069    	 +	166	15799717	-	Z0040	-	transcriptional regulator of cai operon	
38	 54.90       39188..39799    	 -	203	15799718	caiE	Z0041	R	possible synthesis of cofactor for carnitine racemase and dehydratase	
39	 52.46       39784..40677    	 -	297	15799719	caiD	Z0042	I	carnitine racemase	
40	 50.61       40678..42246    	 -	522	15799720	caiC	Z0043	I	probable crotonobetaine/carnitine-CoA ligase	
41	 52.46       42305..43522    	 -	405	15799721	caiB	Z0044	C	l-carnitine dehydratase	
42	 53.81       43651..44793    	 -	380	15799722	caiA	Z0045	I	probable carnitine operon oxidoreductase	
43	 51.68       44824..46338    	 -	504	15799723	caiT	Z0046	M	probable carnitine transporter	
44	 51.67       46781..47587    	 +	268	15799724	fixA	Z0047	C	probable flavoprotein subunit, carnitine metabolism	
45	 55.94       47602..48543    	 +	313	15799725	fixB	Z0048	C	probable flavoprotein subunit, carnitine metabolism	
46	 54.78       48594..49880    	 +	428	15799726	fixC	Z0049	C	flavoprotein; electron transport	
47	 56.94 +1    49877..50164    	 +	95	15799727	fixX	Z0050	C	putative ferredoxin	
48	 53.38       50222..51553    	 +	443	15799728	yaaU	Z0051	G	putative transport protein	
49	 54.80       51661..52191    	 +	176	15799729	yabF	Z0052	R	putative NAD(P)H oxidoreductase	
50	 55.82       52184..54046    	 +	620	15799730	kefC	Z0053	P	K+ efflux antiporter, glutathione-regulated	
51	 53.33       54238..54717    	 +	159	15799731	-	Z0055	H	dihydrofolate reductase type I; trimethoprim resistance	
52	 48.72       54803..55036    	 +	77	15799732	-	Z0056	-	putative antitoxin of gyrase inhibiting toxin-antitoxin system	
53	 45.71       55039..55353    	 +	104	15799733	-	Z0057	-	putative toxin of gyrase inhibiting toxin-antitoxin system	
54	 55.95       55350..56198    	 -	282	15799734	apaH	Z0058	T	diadenosine tetraphosphatase	
55	 51.85       56205..56582    	 -	125	15799735	apaG	Z0059	P	orf, hypothetical protein	
56	 53.16       56585..57406    	 -	273	15799736	ksgA	Z0060	J	S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase	
57	 56.16       57403..58392    	 -	329	15799737	pdxA	Z0061	H	pyridoxine biosynthesis	
58	 53.77       58392..59678    	 -	428	15799738	surA	Z0062	O	survival protein	
59	 51.34       59731..62085    	 -	784	15799739	imp	Z0063	M	organic solvent tolerance	
60	 52.82       62340..63155    	 +	271	15799740	yabH	Z0064	O	putative DNA binding protein	
61	 41.83 -1    63450..64202    	 +	250	15799741	-	Z0065	-	-	
62	 54.09       64620..65279    	 -	219	15799742	yabO	Z0066	J	orf, hypothetical protein	
63	 55.01       65291..68197    	 -	968	15799743	-	Z0067	K	-	
64	 55.57       68361..70712    	 -	783	15799744	polB	Z0068	L	DNA polymerase II	
65	 54.89       70787..71482    	 -	231	15799745	araD	Z0069	G	L-ribulose-5-phosphate 4-epimerase	
66	 55.62       71682..73184    	 -	500	15799746	araA	Z0070	G	L-arabinose isomerase	
67	 57.97 +1    73195..74895    	 -	566	15799747	araB	Z0072	C	L-ribulokinase	
68	 52.90       75234..76112    	 +	292	15799748	araC	Z0073	K	transcriptional regulator for ara operon	
69	 54.38       76198..76962    	 +	254	15799749	yabI	Z0074	S	orf, hypothetical protein	
70	 56.94 +1    77049..77747    	 -	232	15799750	yabJ	Z0075	H	putative ATP-binding component of a transport system	
71	 58.97 +1    77731..79341    	 -	536	15799751	yabK	Z0076	H	putative transport system permease protein	
72	 52.95       79317..80300    	 -	327	15799752	tbpA	Z0077	H	thiamin-binding periplasmic protein	
73	 43.16 -1    80672..81241    	 +	189	15799753	-	Z0078	-	-	
74	 55.21       81470..83128    	 -	552	15799754	yabN	Z0079	E	putative transport protein	
75	 52.31       83456..84061    	 -	201	15799755	leuD	Z0080	E	isopropylmalate isomerase subunit	
76	 55.67       84072..85472    	 -	466	15799756	leuC	Z0081	E	3-isopropylmalate isomerase (dehydratase) subunit	
77	 54.89       85475..86569    	 -	364	15799757	leuB	Z0082	E	3-isopropylmalate dehydrogenase	
78	 53.12       86566..88137    	 -	523	15799758	leuA	Z0083	E	2-isopropylmalate synthase	
79	 47.13       88230..88316    	 -	28	15799759	leuL	Z0084	-	leu operon leader peptide	
80	 45.79       88956..89918    	 +	320	15799760	leuO	Z0086	K	probable transcriptional activator for leuABCD operon	
81	 52.40       90152..91960    	 +	602	15799761	ilvI	Z0087	E	acetolactate synthase III, valine sensitive, large subunit	
82	 49.39       91963..92454    	 +	163	15799762	ilvH	Z0088	E	acetolactate synthase III, valine sensitive, small subunit	
83	 44.83       92466..92552    	 +	28	15799763	fruL	Z0089	-	fruR leader peptide	
84	 54.83       92634..93638    	 +	334	15799764	fruR	Z0090	K	transcriptional repressor of fru operon and others	
85	 52.29       94240..94698    	 +	152	15799765	yabB	Z0091	S	orf, hypothetical protein	
86	 54.88       94700..95641    	 +	313	15799766	yabC	Z0092	M	putative apolipoprotein	
87	 50.55       95638..96003    	 +	121	15799767	ftsL	Z0093	D	cell division protein; ingrowth of wall at septum	
88	 53.65       96019..97785    	 +	588	15799768	ftsI	Z0094	M	septum formation; penicillin-binding protein 3; peptidoglycan synthetase	
89	 56.18       97772..99259    	 +	495	15799769	murE	Z0095	M	meso-diaminopimelate-adding enzyme	
90	 54.75       99256..100614   	 +	452	15799770	murF	Z0096	M	D-alanine:D-alanine-adding enzyme	
91	 53.09      100608..101690   	 +	360	15799771	mraY	Z0097	M	phospho-N-acetylmuramoyl-pentapeptide transferase?	
92	 55.20      101693..103009   	 +	438	15799772	murD	Z0098	M	UDP-N-acetylmuramoylalanine-D-glutamate ligase	
93	 52.85      103009..104253   	 +	414	15799773	ftsW	Z0099	D	cell division; membrane protein involved in shape determination	
94	 55.99      104250..105317   	 +	355	15799774	murG	Z0100	M	UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	
95	 54.54      105371..106846   	 +	491	15799775	murC	Z0101	M	L-alanine adding enzyme, UDP-N-acetyl-muramate:alanine ligase	
96	 51.68      106839..107759   	 +	306	15799776	ddlB	Z0102	M	D-alanine-D-alanine ligase B, affects cell division	
97	 53.55      107761..108591   	 +	276	15799777	ftsQ	Z0103	M	cell division protein; ingrowth of wall at septum	
98	 52.26      108588..109850   	 +	420	15799778	ftsA	Z0104	D	ATP-binding cell division protein, septation process, complexes with FtsZ, associated with junctions of inner and outer membranes	
99	 54.25      109911..111062   	 +	383	15799779	ftsZ	Z0105	D	cell division; forms circumferential ring; tubulin-like GTP-binding protein and GTPase	
100	 51.20      111163..112080   	 +	305	15799780	lpxC	Z0106	M	UDP-3-O-acyl N-acetylglucosamine deacetylase; lipid A biosynthesis	

 
 50.36 MEAN 
 
 5.88  STD DEV 



Last Updated: Sept 17 2004 (Note: update adds new organisms but does not affect the existing records)

Funding for this work was provided by the Peter Wall Institute for Advanced Studies. This service is hosted by the Brinkman Laboratory of the Department of Molecular Biology and Biochemistry at Simon Fraser University.