IslandPathversion 1.0 




IslandPath Analysis: Escherichia coli K12



Each circle in the graphic corresponds to a predicted protein-coding ORF in the genome.
Circle colours indicate if an ORF has a higher or lower %G+C than cutoffs you set below
--(default is +/- 3.48 of the mean %G+C).
Strike lines across the circles represent regions with dinucleotide bias above a pre-determined cutoff.
Click on a circle to view a different portion of the table presented below the graph (default is the first 100 ORFs).




A yellow circle indicates its %G+C value is bigger than the high value.
A green circle indicates its %G+C value is bigger than the low value and smaller than the high value.
A pink circle indicates its %G+C value is smaller than the low value.

A strike line across the circles indicates the region has dinucleotide bais above 1 STD DEV.
A black verticle bar indicates a transfer RNA gene lies between the two ORFs.
A purple verticle bar indicates a ribosomal RNA gene lies between the two ORFs.
A deep blue verticle bar indicates both a tRNA and rRNA gene lie between the two ORFs.
A black square indicates the dot is annotated as a transposase.
A black triangle indicates the dot is annotated as an integrase.


Low:  High:    Mean: 50.99   STD DEV: 4.90

Escherichia coli K12, complete genome - 0..4639221
4279 proteins

Pos	 %G+C  SD      Location		Strand	Length	PID	Gene	Synonym	Code	Product

1	 51.52         190..255      	 +	21	16127995	thrL	b0001	-	thr operon leader peptide	
2	 53.07         337..2799     	 +	820	16127996	thrA	b0002	E	aspartokinase I, homoserine dehydrogenase I	
3	 56.27 +1     2801..3733     	 +	310	16127997	thrB	b0003	E	homoserine kinase	
4	 52.84        3734..5020     	 +	428	16127998	thrC	b0004	E	threonine synthase	
5	 53.87        5234..5530     	 +	98	16127999	-	b0005	-	orf, hypothetical protein	
6	 49.68        5683..6459     	 -	258	16128000	yaaA	b0006	S	orf, hypothetical protein	
7	 53.32        6529..7959     	 -	476	16128001	yaaJ	b0007	E	inner membrane transport protein	
8	 51.99        8238..9191     	 +	317	16128002	talB	b0008	G	transaldolase B	
9	 54.42        9306..9893     	 +	195	16128003	mog	b0009	H	required for the efficient incorporation of molybdate into molybdoproteins	
10	 53.09        9928..10494    	 -	188	16128004	yaaH	b0010	R	orf, hypothetical protein	
11	 50.84       10643..11356    	 -	237	16128005	b0011	b0011	-	putative oxidoreductase	
12	 50.59       10725..11315    	 +	196	16128006	htgA	b0012	-	positive regulator for sigma 32 heat shock promoters	
13	 48.89       11382..11786    	 -	134	16128007	yaaI	b0013	-	orf, hypothetical protein	
14	 51.12       12163..14079    	 +	638	16128008	dnaK	b0014	O	chaperone Hsp70; DNA biosynthesis; autoregulated heat shock proteins	
15	 55.17       14168..15298    	 +	376	16128009	dnaJ	b0015	O	chaperone with DnaK; heat shock protein	
16	 51.93       15445..16557    	 +	370	16128010	yi81_1	b0016	L	IS186 hypothetical protein	
17	 52.10       15869..16177    	 -	102	16128011	yi82_1	b0017	-	IS186 and IS421 hypothetical protein	
18	 51.43       16751..16960    	 -	69	16128012	gef	b0018	-	Gef protein interferes with membrane function when in excess	
19	 51.41       17489..18655    	 +	388	16128013	nhaA	b0019	P	Na+/H antiporter, pH dependent	
20	 47.46       18715..19620    	 +	301	16128014	nhaR	b0020	K	transcriptional activator of nhaA	
21	 54.56       19811..20314    	 -	167	16128015	insB_1	b0021	L	IS1 protein InsB	
22	 52.90       20233..20508    	 -	91	16128016	insA_1	b0022	L	IS1 protein InsA	
23	 46.59       20815..21078    	 -	87	16128017	rpsT	b0023	J	30S ribosomal subunit protein S20	
24	 48.86       21181..21399    	 +	72	16128018	b0024	b0024	-	orf, hypothetical protein	
25	 53.61       21407..22348    	 +	313	16128019	ribF	b0025	H	putative regulator	
26	 55.77       22391..25207    	 +	938	16128020	ileS	b0026	J	isoleucine tRNA synthetase	
27	 53.54       25207..25701    	 +	164	16128021	lspA	b0027	N	prolipoprotein signal peptidase (SPase II)	
28	 54.44       25826..26275    	 +	149	16128022	slpA	b0028	O	probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase (a rotamase)	
29	 55.10       26277..27227    	 +	316	16128023	lytB	b0029	I	control of stringent response; involved in penicillin tolerance	
30	 56.28 +1    27293..28207    	 +	304	16128024	yaaF	b0030	F	orf, hypothetical protein	
31	 53.41       28374..29195    	 +	273	16128025	dapB	b0031	E	dihydrodipicolinate reductase	
32	 53.35       29651..30799    	 +	382	16128026	carA	b0032	E	carbamoyl-phosphate synthetase, glutamine (small) subunit	
33	 56.27 +1    30817..34038    	 +	1073	16128027	carB	b0033	E	carbamoyl-phosphate synthase large subunit	
34	 35.56 -2    34086..34265    	 -	59	16132238	yaaV	b0033a	-	Uncharacterized conserved protein	
35	 43.51 -1    34195..34695    	 +	166	16128028	caiF	b0034	-	transcriptional regulator of cai operon	
36	 54.74       34781..35392    	 -	203	16128029	caiE	b0035	R	possible synthesis of cofactor for carnitine racemase and dehydratase	
37	 52.35       35377..36270    	 -	297	16128030	caiD	b0036	I	carnitine racemase	
38	 50.99       36271..37839    	 -	522	16128031	caiC	b0037	I	probable crotonobetaine/carnitine-CoA ligase	
39	 52.63       37898..39115    	 -	405	16128032	caiB	b0038	C	l-carnitine dehydratase	
40	 53.89       39244..40386    	 -	380	16128033	caiA	b0039	I	probable carnitine operon oxidoreductase	
41	 51.82       40417..41931    	 -	504	16128034	caiT	b0040	M	probable carnitine transporter	
42	 52.04       42367..43173    	 +	268	16128035	fixA	b0041	C	probable flavoprotein subunit, carnitine metabolism	
43	 56.69 +1    43188..44129    	 +	313	16128036	fixB	b0042	C	probable flavoprotein subunit, carnitine metabolism	
44	 54.93       44180..45466    	 +	428	16128037	fixC	b0043	C	flavoprotein; electron transport	
45	 56.94 +1    45463..45750    	 +	95	16128038	fixX	b0044	C	putative ferredoxin	
46	 53.30       45807..47138    	 +	443	16128039	yaaU	b0045	G	putative transport protein	
47	 54.61       47246..47776    	 +	176	16128040	yabF	b0046	R	putative NAD(P)H oxidoreductase	
48	 55.50       47769..49631    	 +	620	16128041	kefC	b0047	P	K+ efflux antiporter, glutathione-regulated	
49	 52.71       49823..50302    	 +	159	16128042	folA	b0048	H	dihydrofolate reductase type I; trimethoprim resistance	
50	 55.75       50380..51222    	 -	280	16128043	apaH	b0049	T	diadenosine tetraphosphatase	
51	 51.85       51229..51606    	 -	125	16128044	apaG	b0050	P	orf, hypothetical protein	
52	 53.04       51609..52430    	 -	273	16128045	ksgA	b0051	J	S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase	
53	 56.36 +1    52427..53416    	 -	329	16128046	pdxA	b0052	H	pyridoxine biosynthesis	
54	 53.85       53416..54702    	 -	428	16128047	surA	b0053	O	survival protein	
55	 51.38       54755..57109    	 -	784	16128048	imp	b0054	M	organic solvent tolerance	
56	 52.70       57364..58179    	 +	271	16128049	yabH	b0055	O	putative DNA binding protein	
57	 45.16 -1    58474..59124    	 +	216	16128050	yabP	b0056	-	orf, hypothetical protein	
58	 33.96 -2    59121..59279    	 +	52	16128051	yabQ	b0057	-	orf, hypothetical protein	
59	 53.94       59687..60346    	 -	219	16128052	yabO	b0058	J	pseudouridylate synthase	
60	 54.90       60358..63264    	 -	968	16128053	hepA	b0059	K	probable ATP-dependent RNA helicase	
61	 55.36       63429..65780    	 -	783	16128054	polB	b0060	L	DNA polymerase II	
62	 55.32       65855..66550    	 -	231	16128055	araD	b0061	G	L-ribulose-5-phosphate 4-epimerase	
63	 55.49       66835..68337    	 -	500	16128056	araA	b0062	G	L-arabinose isomerase	
64	 58.02 +1    68348..70048    	 -	566	16128057	araB	b0063	C	L-ribulokinase	
65	 52.56       70387..71265    	 +	292	16128058	araC	b0064	K	transcriptional regulator for ara operon	
66	 53.86       71351..72115    	 +	254	16128059	yabI	b0065	S	orf, hypothetical protein	
67	 57.08 +1    72229..72927    	 -	232	16128060	yabJ	b0066	H	putative ATP-binding component of a transport system	
68	 58.41 +1    72911..74521    	 -	536	16128061	yabK	b0067	H	putative transport system permease protein	
69	 53.25       74497..75480    	 -	327	16128062	tbpA	b0068	H	thiamin-binding periplasmic protein	
70	 54.89       75644..77299    	 -	551	16128063	yabN	b0069	E	putative transport protein	
71	 48.43       77621..78799    	 +	392	16128064	yabM	b0070	G	putative transport protein	
72	 51.49       78848..79453    	 -	201	16128065	leuD	b0071	E	isopropylmalate isomerase subunit	
73	 55.75       79464..80864    	 -	466	16128066	leuC	b0072	E	3-isopropylmalate isomerase (dehydratase) subunit	
74	 55.53       80867..81961    	 -	364	16128067	leuB	b0073	E	3-isopropylmalate dehydrogenase	
75	 52.99       81958..83529    	 -	523	16128068	leuA	b0074	E	2-isopropylmalate synthase	
76	 47.13       83622..83708    	 -	28	16128069	leuL	b0075	-	leu operon leader peptide	
77	 43.76 -1    84191..85312    	 +	373	16128070	leuO	b0076	K	probable transcriptional activator for leuABCD operon	
78	 52.93       85630..87354    	 +	574	16132273	ilvI	b0077m	E	acetolactate synthase isozyme III large subunit	
79	 50.20       87357..87848    	 +	163	16128071	ilvH	b0078	E	acetolactate synthase III, valine sensitive, small subunit	
80	 44.83 -1    87860..87946    	 +	28	16128072	fruL	b0079	-	fruR leader peptide	
81	 54.93       88028..89032    	 +	334	16128073	fruR	b0080	K	transcriptional repressor of fru operon and others	
82	 52.07       89634..90092    	 +	152	16128074	yabB	b0081	S	orf, hypothetical protein	
83	 55.20       90094..91035    	 +	313	16128075	yabC	b0082	M	putative apolipoprotein	
84	 50.27       91032..91397    	 +	121	16128076	ftsL	b0083	D	cell division protein; ingrowth of wall at septum	
85	 53.99       91413..93179    	 +	588	16128077	ftsI	b0084	M	septum formation; penicillin-binding protein 3; peptidoglycan synthetase	
86	 56.59 +1    93166..94653    	 +	495	16128078	murE	b0085	M	meso-diaminopimelate-adding enzyme	
87	 55.11       94650..96008    	 +	452	16128079	murF	b0086	M	D-alanine:D-alanine-adding enzyme	
88	 53.37       96002..97084    	 +	360	16128080	mraY	b0087	M	phospho-N-acetylmuramoyl-pentapeptide transferase?	
89	 54.90       97087..98403    	 +	438	16128081	murD	b0088	M	UDP-N-acetylmuramoylalanine-D-glutamate ligase	
90	 53.01       98403..99647    	 +	414	16128082	ftsW	b0089	D	cell division; membrane protein involved in shape determination	
91	 56.09 +1    99644..100711   	 +	355	16128083	murG	b0090	M	UDP-N-acetylglucosamine:N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	
92	 54.74      100765..102240   	 +	491	16128084	murC	b0091	M	L-alanine adding enzyme, UDP-N-acetyl-muramate:alanine ligase	
93	 51.57      102233..103153   	 +	306	16128085	ddlB	b0092	M	D-alanine-D-alanine ligase B, affects cell division	
94	 53.31      103155..103985   	 +	276	16128086	ftsQ	b0093	M	cell division protein; ingrowth of wall at septum	
95	 52.10      103982..105244   	 +	420	16128087	ftsA	b0094	D	ATP-binding cell division protein, septation process, complexes with FtsZ, associated with junctions of inner and outer membranes	
96	 54.17      105305..106456   	 +	383	16128088	ftsZ	b0095	D	cell division; forms circumferential ring; tubulin-like GTP-binding protein and GTPase	
97	 51.09      106557..107474   	 +	305	16128089	lpxC	b0096	M	UDP-3-O-acyl N-acetylglucosamine deacetylase; lipid A biosynthesis	
98	 52.38      107630..108217   	 +	195	16128090	yacA	b0097	-	orf, hypothetical protein	
99	 52.40      108279..110984   	 +	901	16128091	secA	b0098	N	preprotein translocase; secretion protein	
100	 49.23      111044..111433   	 +	129	16128092	mutT	b0099	L	7,8-dihydro-8-oxoguanine-triphosphatase, prefers dGTP, causes AT-GC transversions	

 
 50.99 MEAN 
 
 4.90  STD DEV 






Last Updated: Sept 17 2004 (Note: update adds new organisms but does not affect the existing records)

      
Funding for this work was provided by the Peter Wall Institute for Advanced Studies. This service is hosted by the Brinkman Laboratory of the Department of Molecular Biology and Biochemistry at Simon Fraser University.