IslandPathversion 1.0

IslandPath Analysis: Shigella flexneri 2a 2457T



Each circle in the graphic corresponds to a predicted protein-coding ORF in the genome. Circle colours indicate if an ORF has a higher or lower %G+C than cutoffs you set below --(default is +/- 3.48 of the mean %G+C). Strike lines across the circles represent regions with dinucleotide bias above a pre-determined cutoff. Click on a circle to view a different portion of the table presented below the graph (default is the first 100 ORFs).
No rRNA data available A yellow circle indicates its %G+C value is bigger than the high value. A green circle indicates its %G+C value is bigger than the low value and smaller than the high value. A pink circle indicates its %G+C value is smaller than the low value. A strike line across the circles indicates the region has dinucleotide bais above 1 STD DEV. A black verticle bar indicates a transfer RNA gene lies between the two ORFs. A purple verticle bar indicates a ribosomal RNA gene lies between the two ORFs. A deep blue verticle bar indicates both a tRNA and rRNA gene lie between the two ORFs. A black square indicates the dot is annotated as a transposase. A black triangle indicates the dot is annotated as an integrase. Low: High: Mean: 51.57 STD DEV: 4.04
Shigella flexneri 2a str. 2457T, complete genome - 0..4599354
4068 proteins

Pos	 %G+C  SD      Location		Strand	Length	PID	Gene	Synonym	Code	Product

1	 51.52      190..255      	 +	21	30061572	thrL	S0001	-	thr operon leader peptide	
2	 53.31         336..2798     	 +	820	30061573	thrA	S0002	-	aspartokinase I, homoserine dehydrogenase I	
3	 56.27 +1     2800..3732     	 +	310	30061574	thrB	S0003	-	homoserine kinase	
4	 53.07        3733..5019     	 +	428	30061575	thrC	S0004	-	threonine synthase	
5	 54.86        5242..5529     	 +	95	30061576	-	S0005	-	hypothetical protein	
6	 49.55        5682..6458     	 -	258	30061577	yaaA	S0006	S	hypothetical protein	
7	 51.78        8237..9190     	 +	317	30061578	talB	S0008	G	transaldolase B	
8	 54.08        9305..9892     	 +	195	30061579	mog	S0009	H	molybdopterin biosynthesis protein	
9	 53.26        9927..10493    	 -	188	30061580	yaaH	S0010	S	hypothetical protein	
10	 50.56       10642..11355    	 -	237	30061581	-	S0012	-	putative oxidoreductase	
11	 50.83       10715..11314    	 +	199	30061582	htgA	S0011	-	positive regulator for sigma 32 heat shock promoters	
12	 48.40       11381..11785    	 -	134	30061583	yaaI	S0013	-	hypothetical protein	
13	 51.17       12162..14078    	 +	638	30061584	dnaK	S0014	-	chaperone Hsp70; autoregulated heat shock protein	
14	 55.08       14167..15297    	 +	376	30061585	dnaJ	S0015	-	chaperone with DnaK; heat shock protein	
15	 51.43       15401..15610    	 -	69	30061586	gef	S0017	-	membrane toxin	
16	 51.24       16139..17305    	 +	388	30061587	nhaA	S0018	-	Na+/H+ antiporter	
17	 47.44 -1    17371..18270    	 +	299	30061588	nhaR	S0019	-	transcriptional activator of nhaA	
18	 52.98       18683..19186    	 -	167	30061589	-	S0020	-	IS1 orfB	
19	 52.54       19105..19380    	 -	91	30061590	-	S0021	-	IS1 orfA	
20	 45.70 -1    19769..19954    	 -	61	30061591	rpsT	S0022	-	30S ribosomal subunit protein S20	
21	 48.40       20135..20353    	 +	72	30061592	-	S0023	-	hypothetical protein	
22	 52.97       20361..21302    	 +	313	30061593	ribF	S0024	H	putative regulator	
23	 55.66 +1    21345..24161    	 +	938	30061594	ileS	S0025	-	isoleucine tRNA synthetase	
24	 53.74       24161..24655    	 +	164	30061595	lspA	S0026	-	prolipoprotein signal peptidase (SPase II)	
25	 54.89       24742..25191    	 +	149	30061596	slpA	S0027	O	probable FKBX-type 16kD peptidyl-prolyl cis-trans isomerase (a rotamase)	
26	 55.10       25193..26143    	 +	316	30061597	lytB	S0028	-	LytB protein	
27	 55.74 +1    26209..27123    	 +	304	30061598	yaaF	S0029	-	hypothetical protein	
28	 53.04       27290..28111    	 +	273	30061599	dapB	S0030	-	dihydrodipicolinate reductase	
29	 53.44       28567..29715    	 +	382	30061600	carA	S0031	-	carbamoyl-phosphate synthetase, glutamine (small) subunit	
30	 55.71 +1    29733..32954    	 +	1073	30061601	carB	S0032	E	carbamoyl-phosphate synthase large subunit	
31	 43.31 -2    33111..33611    	 +	166	30061602	caiF	S0033	-	transcriptional regulator of cai operon	
32	 54.41       33697..34308    	 -	203	30061603	caiE	S0034	-	carnitine operon protein CaiE	
33	 52.35       34293..35186    	 -	297	30061604	caiD	S0035	-	carnitine racemase	
34	 50.73       35187..36755    	 -	522	30061605	caiC	S0036	-	probable crotonobetaine/carnitine-CoA ligase	
35	 52.46       36814..38031    	 -	405	30061606	caiB	S0037	-	l-carnitine dehydratase	
36	 53.89       38160..39302    	 -	380	30061607	caiA	S0038	I	probable carnitine operon oxidoreductase	
37	 52.21       39333..40847    	 -	504	30061608	caiT	S0039	-	probable carnitine transporter	
38	 52.17       41167..41973    	 +	268	30061609	fixA	S0040	-	probable flavoprotein subunit	
39	 55.17       42980..44266    	 +	428	30061610	fixC	S0042	-	flavoprotein	
40	 56.60 +1    44263..44550    	 +	95	30061611	fixX	S0043	-	putative ferredoxin	
41	 52.26       44609..46003    	 +	464	30061612	yaaU	S0044	-	putative transport protein	
42	 55.37       46051..46581    	 +	176	30061613	yabF	S0045	-	putative NAD(P)H oxidoreductase	
43	 55.29       46574..48436    	 +	620	30061614	kefC	S0046	-	K+ efflux antiporter	
44	 52.92       48627..49106    	 +	159	30061615	folA	S0047	H	dihydrofolate reductase type I	
45	 55.99 +1    49184..50026    	 -	280	30061616	apaH	S0048	-	diadenosine tetraphosphatase	
46	 51.85       50033..50410    	 -	125	30061617	apaG	S0049	P	hypothetical protein	
47	 53.41       50413..51234    	 -	273	30061618	ksgA	S0050	-	S-adenosylmethionine-6-N,N-adenosyl (rRNA) dimethyltransferase	
48	 56.26 +1    51231..52220    	 -	329	30061619	pdxA	S0051	-	pyridoxal phosphate biosynthetic protein PdxA	
49	 53.85       52220..53506    	 -	428	30061620	surA	S0052	O	survival protein	
50	 51.38       53559..55913    	 -	784	30061621	imp	S0053	-	organic solvent tolerance protein	
51	 52.94       56168..56983    	 +	271	30061622	yabH	S0054	O	putative DNA-binding protein	
52	 54.24       57100..57759    	 -	219	30061623	yabO	S0055	J	hypothetical protein	
53	 54.87       57771..60677    	 -	968	30061624	hepA	S0056	-	probable ATP-dependent RNA helicase	
54	 55.19       60842..63193    	 -	783	30061625	polB	S0057	-	DNA polymerase II	
55	 55.17       63268..63963    	 -	231	30061626	araD	S0058	-	L-ribulose-5-phosphate 4-epimerase	
56	 55.29       64163..65665    	 -	500	30061627	araA	S0059	-	L-arabinose isomerase	
57	 58.08 +1    65676..67376    	 -	566	30061628	araB	S0060	-	L-ribulokinase	
58	 52.67       67715..68593    	 +	292	30061629	araC	S0061	-	transcriptional regulator for ara operon	
59	 54.51       68679..69443    	 +	254	30061630	yabI	S0062	-	hypothetical protein	
60	 56.94 +1    69557..70255    	 -	232	30061631	yabJ	S0063	-	putative ATP-binding component of a transport system	
61	 58.54 +1    70239..71849    	 -	536	30061632	yabK	S0064	-	putative transport system permease protein	
62	 52.74       71825..72808    	 -	327	30061633	tbpA	S0065	-	thiamin-binding periplasmic protein	
63	 55.19       72972..74627    	 -	551	30061634	yabN	S0066	-	putative transport protein	
64	 48.09       74949..76127    	 +	392	30061635	yabM	S0067	-	putative transport protein	
65	 52.15       76176..76781    	 -	201	30061636	leuD	S0068	-	isopropylmalate isomerase subunit	
66	 55.32       76792..78192    	 -	466	30061637	leuC	S0069	-	3-isopropylmalate isomerase (dehydratase) subunit	
67	 55.25       78195..79289    	 -	364	30061638	leuB	S0070	-	3-isopropylmalate dehydrogenase	
68	 52.74       79286..80857    	 -	523	30061639	leuA	S0071	-	2-isopropylmalate synthase	
69	 47.13 -1    80950..81036    	 -	28	30061640	leuL	S0072	-	leu operon leader peptide	
70	 43.76 -1    81518..82639    	 +	373	30061641	leuO	S0073	-	probable transcriptional activator for leuABCD operon	
71	 52.46       82873..84681    	 +	602	30061642	ilvI	S0074	-	acetolactate synthase III, large subunit	
72	 50.20       84684..85175    	 +	163	30061643	ilvH	S0075	-	acetolactate synthase III, small subunit	
73	 47.13 -1    85188..85274    	 +	28	30061644	fruL	S0076	-	fruR leader peptide	
74	 54.93       85356..86360    	 +	334	30061645	fruR	S0077	K	transcriptional repressor of fru operon and others	
75	 52.54       86483..86758    	 +	91	30061646	-	S0078	-	IS1 orfA	
76	 52.58       86677..87180    	 +	167	30061647	-	S0079	-	IS1 orfB	
77	 52.07       87739..88197    	 +	152	30061648	yabB	S0080	-	hypothetical protein	
78	 55.20       88199..89140    	 +	313	30061649	yabC	S0081	-	putative apolipoprotein	
79	 50.55       89137..89502    	 +	121	30061650	ftsL	S0082	D	cell division protein; in growth of wall at septum	
80	 53.88       89518..91284    	 +	588	30061651	ftsI	S0083	-	penicillin-binding protein 3; peptidoglycan synthetase	
81	 56.79 +1    91271..92758    	 +	495	30061652	murE	S0084	-	meso-diaminopimelate-adding enzyme	
82	 54.82       92755..94113    	 +	452	30061653	murF	S0085	-	D-alanine:D-alanine-adding enzyme	
83	 52.82       94107..95189    	 +	360	30061654	mraY	S0086	M	phospho-N-acetylmuramoyl-pentapeptide transferase	
84	 55.35       95192..96508    	 +	438	30061655	murD	S0087	-	UDP-N-acetylmuramoylalanine-D-glutamate ligase	
85	 52.53       96508..97752    	 +	414	30061656	ftsW	S0088	-	membrane protein	
86	 55.71 +1    97749..98816    	 +	355	30061657	murG	S0089	-	UDP-N-acetylglucosamine:N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	
87	 54.40       98870..100345   	 +	491	30061658	murC	S0090	-	L-alanine adding enzyme, UDP-N-acetyl-muramate:alanine ligase	
88	 51.36      100338..101258   	 +	306	30061659	ddlB	S0091	-	D-alanine-D-alanine ligase B	
89	 53.31      101260..102090   	 +	276	30061660	ftsQ	S0092	-	cell division protein	
90	 52.02      102087..103349   	 +	420	30061661	ftsA	S0093	D	ATP-binding cell division protein	
91	 53.91      103410..104561   	 +	383	30061662	ftsZ	S0094	D	tubulin-like GTP-binding protein and GTPase	
92	 51.20      104662..105579   	 +	305	30061663	lpxC	S0095	M	UDP-3-O-acyl N-acetylglucosamine deacetylase	
93	 52.38      105735..106322   	 +	195	30061664	yacA	S0096	-	hypothetical protein	
94	 52.22      106384..109089   	 +	901	30061665	secA	S0097	-	preprotein translocase; secretion protein	
95	 49.23      109149..109538   	 +	129	30061666	mutT	S0098	-	7,8-dihydro-8-oxoguanine-triphosphatase	
96	 54.81      109553..109687   	 -	44	30061667	-	S0099	-	hypothetical protein	
97	 52.02      109638..109835   	 -	65	30061668	yacG	S0100	S	hypothetical protein	
98	 51.21      109845..110588   	 -	247	30061669	yacF	S0101	-	hypothetical protein	
99	 52.33      110588..111208   	 -	206	30061670	yacE	S0102	-	putative DNA repair protein	
100	 51.72      111433..112476   	 +	347	30061671	guaC	S0103	-	GMP reductase	

 
 51.57 MEAN 
 
 4.04  STD DEV 



Last Updated: Sept 17 2004 (Note: update adds new organisms but does not affect the existing records)

Funding for this work was provided by the Peter Wall Institute for Advanced Studies. This service is hosted by the Brinkman Laboratory of the Department of Molecular Biology and Biochemistry at Simon Fraser University.